WO2002077605A3 - Reentrant cavity bioassay for detecting molecular or cellular events - Google Patents

Reentrant cavity bioassay for detecting molecular or cellular events Download PDF

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Publication number
WO2002077605A3
WO2002077605A3 PCT/US2002/008368 US0208368W WO02077605A3 WO 2002077605 A3 WO2002077605 A3 WO 2002077605A3 US 0208368 W US0208368 W US 0208368W WO 02077605 A3 WO02077605 A3 WO 02077605A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioassay
reentrant cavity
reentrant
cellular events
detecting molecular
Prior art date
Application number
PCT/US2002/008368
Other languages
French (fr)
Other versions
WO2002077605A2 (en
Inventor
Barrett J Bartell
Joseph A Heanue
Mark A Rhodes
Original Assignee
Signature Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signature Bioscience Inc filed Critical Signature Bioscience Inc
Priority to AU2002305063A priority Critical patent/AU2002305063A1/en
Publication of WO2002077605A2 publication Critical patent/WO2002077605A2/en
Publication of WO2002077605A3 publication Critical patent/WO2002077605A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

A reentrant cavity bioassay includes a reentrant cavity and a sample retaining structure. The reentrant cavity includes a reentrant post extending from a first interior surface and terminating proximate to a second interior surface, the gap between the termination of the reentrant post and the second interior surface defining a detection region. The sample retaining structure is configured to retain the sample in the detection region, wherein at least a portion of the sample retaining structure is located within the detection region.
PCT/US2002/008368 2001-03-21 2002-03-18 Reentrant cavity bioassay for detecting molecular or cellular events WO2002077605A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002305063A AU2002305063A1 (en) 2001-03-21 2002-03-18 Reentrant cavity bioassay for detecting molecular or cellular events

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27781001P 2001-03-21 2001-03-21
US60/277,810 2001-03-21
US88031101A 2001-06-12 2001-06-12
US09/880,311 2001-06-12

Publications (2)

Publication Number Publication Date
WO2002077605A2 WO2002077605A2 (en) 2002-10-03
WO2002077605A3 true WO2002077605A3 (en) 2003-11-06

Family

ID=26958728

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/008368 WO2002077605A2 (en) 2001-03-21 2002-03-18 Reentrant cavity bioassay for detecting molecular or cellular events

Country Status (2)

Country Link
AU (1) AU2002305063A1 (en)
WO (1) WO2002077605A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63210757A (en) * 1987-02-27 1988-09-01 Nippon Glass Fiber Co Ltd Device and method for detecting conductive material in nonconductive fiber
WO1999039190A1 (en) * 1998-02-02 1999-08-05 Signature Bioscience Inc. Method and apparatus for detecting molecular binding events
WO2001009606A1 (en) * 1999-08-02 2001-02-08 Signature Bioscience, Inc. Methods for analyzing protein binding events
WO2002101367A2 (en) * 2001-06-12 2002-12-19 Signature Bioscience, Inc. Pipette-loaded bioassay assembly for detecting molecular or cellular events

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63210757A (en) * 1987-02-27 1988-09-01 Nippon Glass Fiber Co Ltd Device and method for detecting conductive material in nonconductive fiber
WO1999039190A1 (en) * 1998-02-02 1999-08-05 Signature Bioscience Inc. Method and apparatus for detecting molecular binding events
WO2001009606A1 (en) * 1999-08-02 2001-02-08 Signature Bioscience, Inc. Methods for analyzing protein binding events
WO2002101367A2 (en) * 2001-06-12 2002-12-19 Signature Bioscience, Inc. Pipette-loaded bioassay assembly for detecting molecular or cellular events

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
EBBE NYFORS ET AL: "INDUSTRIAL MICROWAVE SENSORS", 1989, ARTECH HOUSE, BOSTON, LONDON, ISBN: 0-89006-397-4, XP002247222 *
MCEUEN A ET AL: "Temperature controlled cavity applicator for radio-frequency wave irradiation of mammalian cells in vitro", SYMPOSIUM ON ELECTROMAGNETIC FIELDS IN BIOLOGICAL SYSTEMS, OTTAWA, ONT., CANADA, 27-30 JUNE 1978, 1979, Edmonton, Alta., Canada, Internat. Microwave Power Inst, Canada, pages 113 - 121, XP009013200 *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 001 (P - 808) 6 January 1989 (1989-01-06) *
WEIGUO XI ET AL: "FIELD ANALYSIS OF NEW COAXIAL DIELECTROMETER", IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, IEEE INC. NEW YORK, US, vol. 40, no. 10, 1 October 1992 (1992-10-01), pages 1927 - 1934, XP000307040, ISSN: 0018-9480 *

Also Published As

Publication number Publication date
AU2002305063A1 (en) 2002-10-08
WO2002077605A2 (en) 2002-10-03

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