WO2002067849A3 - Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents - Google Patents

Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents Download PDF

Info

Publication number
WO2002067849A3
WO2002067849A3 PCT/IL2002/000149 IL0200149W WO02067849A3 WO 2002067849 A3 WO2002067849 A3 WO 2002067849A3 IL 0200149 W IL0200149 W IL 0200149W WO 02067849 A3 WO02067849 A3 WO 02067849A3
Authority
WO
WIPO (PCT)
Prior art keywords
reloading
targeted delivery
methods
therapeutic agents
binding pair
Prior art date
Application number
PCT/IL2002/000149
Other languages
French (fr)
Other versions
WO2002067849A2 (en
WO2002067849A8 (en
Inventor
Sabina Glozman
Zur Pierre Beserman
Yosi Morik
Original Assignee
Sabina Glozman
Zur Pierre Beserman
Yosi Morik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sabina Glozman, Zur Pierre Beserman, Yosi Morik filed Critical Sabina Glozman
Priority to US10/416,542 priority Critical patent/US20040047891A1/en
Priority to AU2002233619A priority patent/AU2002233619A1/en
Priority to EP02700554A priority patent/EP1389071A2/en
Publication of WO2002067849A2 publication Critical patent/WO2002067849A2/en
Publication of WO2002067849A3 publication Critical patent/WO2002067849A3/en
Publication of WO2002067849A8 publication Critical patent/WO2002067849A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices

Abstract

A biomedical system for targeted delivery of a therapeutic agent to a tissue region of a subject is provided. The biomedical system comprises: (a) a biomedical device including: (i) a device body designed and configured for implantation within the tissue region of the subject; and (ii) a first member of a binding pair attached to a surface of said device body; and (b) a delivery vehicle including: (i) a carrier particle designed for carrying the therapeutic agent; (ii) a second member of said binding pair attached to said carrier particle, said second member of said binding pair being capable of specifically interacting with said first member of said binding pair thereby enabling targeting of said delivery vehicle to said biomedical device when implanted within said tissue region.
PCT/IL2002/000149 2001-02-26 2002-02-26 Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents WO2002067849A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/416,542 US20040047891A1 (en) 2001-02-26 2002-02-26 Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents
AU2002233619A AU2002233619A1 (en) 2001-02-26 2002-02-26 Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents
EP02700554A EP1389071A2 (en) 2001-02-26 2002-02-26 Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27089001P 2001-02-26 2001-02-26
US60/270,890 2001-02-26

Publications (3)

Publication Number Publication Date
WO2002067849A2 WO2002067849A2 (en) 2002-09-06
WO2002067849A3 true WO2002067849A3 (en) 2003-12-04
WO2002067849A8 WO2002067849A8 (en) 2004-05-27

Family

ID=23033263

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2002/000149 WO2002067849A2 (en) 2001-02-26 2002-02-26 Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents

Country Status (4)

Country Link
US (1) US20040047891A1 (en)
EP (1) EP1389071A2 (en)
AU (1) AU2002233619A1 (en)
WO (1) WO2002067849A2 (en)

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DE102006006796A1 (en) * 2006-02-14 2007-08-16 Tecpharma Licensing Ag Overlapping display
US7572625B2 (en) 2006-05-18 2009-08-11 Boston Scientific Scimed, Inc. Medical devices coated with drug carrier macromolecules
US8685421B2 (en) * 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
US7758635B2 (en) * 2007-02-13 2010-07-20 Boston Scientific Scimed, Inc. Medical device including cylindrical micelles
US10265407B2 (en) 2007-02-15 2019-04-23 Yale University Modular nanodevices for smart adaptable vaccines
WO2008109347A2 (en) * 2007-03-02 2008-09-12 Yale University Methods for ex vivo administration of drugs to grafts using polymeric nanoparticles
JP5471447B2 (en) * 2007-12-25 2014-04-16 国立大学法人山口大学 Drug delivery system
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
ES2385995B2 (en) * 2011-01-10 2013-05-21 Universidade De Santiago De Compostela NANOCAPPSULES WITH POLYMER COVER
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
US9155671B2 (en) 2012-10-16 2015-10-13 Surmodics, Inc. Wound packing device and methods
EP2737902A1 (en) * 2012-11-28 2014-06-04 Zarzatech, Inc. Compositions comprising cimetidine and n,o-carboxymethyl chitosan for the prevention and therapy of pathologies of the skin and the mucous membranes and in the odontostomatological field
KR102233251B1 (en) 2013-04-03 2021-03-26 엔-폴드 엘엘씨 Novel nanoparticle compositions
SG10201800800YA (en) 2013-05-06 2018-03-28 Scholar Rock Inc Compositions and methods for growth factor modulation
US20170119892A1 (en) * 2014-04-04 2017-05-04 President And Fellows Of Harvard College Refillable drug delivery devices and methods of use thereof
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
US9879087B2 (en) 2014-11-12 2018-01-30 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
CA2967595A1 (en) 2014-11-12 2016-05-19 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
KR20180088381A (en) 2015-11-12 2018-08-03 시아맙 쎄라퓨틱스, 인코포레이티드 Glycan-interacting compounds and methods of use
EP3541847A4 (en) 2016-11-17 2020-07-08 Seattle Genetics, Inc. Glycan-interacting compounds and methods of use
MA47812A (en) 2017-03-03 2021-04-14 Seagen Inc COMPOUNDS INTERACTING WITH GLYCAN AND METHODS OF USE
IT201900011055A1 (en) * 2019-07-05 2021-01-05 Broi Ugo Da PORTABLE DIAGNOSTIC DEVICE AND RELATED DIAGNOSTIC METHOD

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0558697A1 (en) * 1991-06-28 1993-09-08 Massachusetts Institute Of Technology Localized oligonucleotide therapy
US6015897A (en) * 1993-12-07 2000-01-18 Neorx Corporation Biotinamido-n-methylglycyl-seryl-o-succinamido-benzyl dota
US6229002B1 (en) * 1995-06-07 2001-05-08 Nexstar Pharmaceuticlas, Inc. Platelet derived growth factor (PDGF) nucleic acid ligand complexes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing

Also Published As

Publication number Publication date
US20040047891A1 (en) 2004-03-11
AU2002233619A1 (en) 2002-09-12
EP1389071A2 (en) 2004-02-18
WO2002067849A2 (en) 2002-09-06
WO2002067849A8 (en) 2004-05-27

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