WO2002045622A2 - Balloon catheter with radiopaque distal tip - Google Patents
Balloon catheter with radiopaque distal tip Download PDFInfo
- Publication number
- WO2002045622A2 WO2002045622A2 PCT/US2001/051106 US0151106W WO0245622A2 WO 2002045622 A2 WO2002045622 A2 WO 2002045622A2 US 0151106 W US0151106 W US 0151106W WO 0245622 A2 WO0245622 A2 WO 0245622A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- radiopaque
- distal
- tip portion
- means comprises
- balloon
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/008—Strength or flexibility characteristics of the catheter tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/008—Strength or flexibility characteristics of the catheter tip
- A61M2025/0081—Soft tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1079—Balloon catheters with special features or adapted for special applications having radio-opaque markers in the region of the balloon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/0069—Tip not integral with tube
Definitions
- This invention relates to the field of intravascular medical devices and more particularly to balloon dilatation and stent delivery catheters which are readily trackable within vasculature in which they are used.
- Intravascular diseases are commonly treated by relatively non-invasive techniques such as percutaneous transluminal angioplasty (PTA) and percutaneous transluminal coronary angioplasty (PTC A).
- PTA percutaneous transluminal angioplasty
- PTC A percutaneous transluminal coronary angioplasty
- a typical balloon catheter has an elongate shaft with a balloon attached proximate the distal end and a manifold attached to the proximal end.
- the balloon catheter is advanced over the guidewire such that the balloon is positioned adjacent a restriction in a diseased vessel.
- the balloon is then inflated and the restriction in the vessel is opened.
- intravascular catheters for use in such procedures, including fixed-wire (F ) catheters, over-the-wire (OTW) catheters and single- operator-exchange (SOE) catheters.
- F fixed-wire
- OGW over-the-wire
- SOE single- operator-exchange
- An example of an OTW catheter may be found in commonly assigned U.S. Patent No. 5,047,045 to Arney et al.
- An example of an SOE balloon catheter is disclosed in commonly assigned U.S. Patent No. 5,156,594 to Keith.
- Pushability refers to the ability to transmit force from the proximal end of the catheter to the distal end of the catheter.
- Trackability refers to the ability to navigate tortuous vasculature.
- Crossability refers to the ability to navigate the balloon catheter across narrow restrictions in the vasculature, such as stenosed vessels or fully and partially deployed stents.
- a stainless steel outer tube also referred to as a hypotube
- hypotubing is often prone to kinking.
- some prior art catheters use a relatively stiff polymer (e.g., composite) or reinforced polymer in the proximal shaft section.
- the catheter should have a relatively stiff proximal section.
- the catheter should have a relatively flexible distal section.
- the catheter should have a distal tip, the location of which within the vessel can be readily determined so that the progress of the catheter through the vessel can be followed.
- kinking can occur at the joint between the relatively stiff proximal shaft section and the relatively flexible distal shaft section.
- some prior art catheters use one or more tubular sections of intermediate flexibility between the relatively stiff proximal section and the relatively flexible distal section to provide a more gradual transition in flexibility theretween. While this approach provides some benefit, the resulting transition in flexibility is often step-wise, and can still be susceptible to kinking at the junctions of the various intermediate sections.
- an intravascular catheter that has a more gradual transition in flexibility along its length has been needed. A catheter satisfying this need is described in commonly assigned U.S. Patent No. 5,891,110 to Larson et al., which is incorporated herein by reference.
- the guidewire it is also possible for the guidewire to be misdirected by threading it between the stent and the wall of the vessel instead of through the stent lumen. The end result would be that the balloon catheter would get stuck in the vessel and could not be easily removed.
- Previous attempts to provide catheters that are more readily visualized within the vessel have involved the utilization of radiopaque markers in catheters. For example, it has been proposed to track the balloon of a balloon catheter by placing radiopaque bands inside the balloon. Such bands, however, are of little assistance in positioning the distal-most end of the catheter tip, which may be separated from the balloon by a distance of several centimeters.
- the present invention overcomes many of the disadvantages of the prior art by providing a balloon catheter having a distal tip which can be readily located and its position closely followed within vasculature in which it is deployed.
- the balloon catheter of the present invention is rendered radiopaque proximate the distal-most tip thereof, enabling the physician to observe the position of the tip of the catheter within the body of the patient. Precise placement of the catheter tip by the physician is thereby facilitated.
- Radiopacity can be imparted proximate the distal-most tip of the catheter in any of various ways. These include, among others, (1) embedding the catheter tip with radiopaque powder or particles, (2) applying a radiopaque pigment, such as a paint or ink, to the surface of the tip of the catheter, (3) using a radiopaque contrast media to coat the interior surface of a balloon immediately adjacent the distal-most end of the catheter tip, (4) providing bands of radiopaque material proximate the distal-most end of the catheter tip, (5) providing a coil of radiopaque material encircling the distal-most end of the catheter tip, (6) covering at least part of the catheter tip adjacent the distal-most end thereof with a radiopaque mesh or braid, (7) incorporating radiopaque wires in the wall of at least part of the catheter tip adjacent the distal-most end thereof, (8) capping the distal-most end of the catheter tip with a radiopaque cap, and (9) using an arc of a
- Rendering the catheter tip radiopaque proximate its distal-most end is especially important in balloon catheters, because guiding the catheter tip within stenosed vasculature and particularly through stents deployed therein requires knowledge of the precise position of the catheter tip.
- a radiopaque catheter tip of the present invention can be viewed within body vasculature from outside the body to enable precise maneuvering and placement of the catheter with respect to the stenosed area or to facilitate passage through deployed stents and the like.
- Figure 1 is a cross-sectional view of a representative prior art catheter of the type used with the present invention
- Figure 2 is a partial cross-sectional view of a prior art distal tip area of a catheter as in Figure 1;
- Figure 3 is a partial cross-sectional view of another prior art design of the distal tip area of the catheter of Figure 1;
- Figure 4 is a plan view of the distal end of a balloon catheter showing one preferred embodiment of the present invention
- Figure 5 is a plan view of another preferred embodiment of the present invention.
- Figure 6A is a plan view of another preferred embodiment of the present invention.
- Figure 6B is a cross-section of the embodiment of Figure 6A along the line 6B-6B;
- Figure 7 is a plan view of another preferred embodiment of the present invention.
- Figure 8A is a plan view of another preferred embodiment of the present invention.
- Figure 8B is a cross-section of the embodiment of Figure 8A along the line
- Figure 9 is a plan view of another preferred embodiment of the present invention.
- Figure 10 is a plan view of another preferred embodiment of the present invention.
- Figure 11 is a plan view of another preferred embodiment of the present invention.
- Figure 12 is a partial cross-sectional view of another preferred embodiment of the present invention. Detailed Description of the Invention
- FIG. 1 is a cross-sectional view of an over- the-wire (OTW) balloon catheter, which is representative of one type of catheter that can incorporate the present invention.
- OGW over-the-wire
- intravascular catheters suitable for incorporating the present invention include fixed-wire (FW) catheters and single-operator-exchange (SOE) catheters.
- the balloon catheter 20 includes a shaft assembly 22 and a balloon assembly 24 connected proximate the distal end of shaft assembly 22.
- a conventional OTW- type manifold assembly 26 is connected to the proximal end of the shaft assembly 22.
- the shaft assembly 22 includes an inner tube 28 having a proximal end 30 and a distal end 32. The proximal end of the shaft assembly 21 extends into a manifold assembly 26 adhesively bonded to the shaft assembly 22.
- a polyurethane strain relief 23 is snap-fit to the manifold assembly 26, and the shaft assembly 22 extends into the manifold assembly 26 through the polyurethane strain relief 23.
- An outer tube 34 is co-axially disposed about the inner tube 28 to define an annular inflation lumen 37 therebetween.
- the balloon assembly 24 includes a balloon body portion 36 with a proximal balloon waist 38 and a distal balloon waist 40.
- the proximal balloon waist 38 is connected to the outer tube 34 near its distal end 42 by means of an adhesive 44, or alternatively, is thermally bonded.
- the distal balloon waist 40 is connected to the inner tube 28 near its distal end 32 by means of an adhesive bond 48 or a thermal bond such that the interior of the balloon 46 is in fluid communication with the annular inflation lumen 37.
- a radiopaque marker band 50 may be adhesively secured with cyanoacrylate to the inner tube 28 at a point underneath the balloon body 36.
- the marker band may be swaged onto the outer surface of the inner tube 28 within the balloon.
- the inner tube 28 defines a guidewire lumen 54, which provides a passage for a guidewire (not shown).
- the outer tube 34 defines an annular inflation lumen 37, which is in fluid communication with the interior of the balloon 46.
- the catheter of the present invention includes an outer tube 34 which may have multiple segments including a relatively stiff proximal outer section, a mid-shaft section of lesser stiffness, and a tapering distal outer section of the least stiffness.
- the progressive arrangement of more flexible materials as the catheter proceeds distally provides an optimal level of pushability and trackability to navigate tortuous vasculature.
- the flexibility of the sections of the outer tubular member were tested utilizing a Gurley bending resistance tester, Part No. 4171-DT, as manufactured by Precision Instruments, Troy, New York.
- the apparatus consists of a balanced pendulum or pointer which is center-pivoted and can be weighted at three points below its center. The pointer moves freely in both the left and right directions.
- a sample of specific size is attached to a clamp, which in turn is located in one of several positions on a motorized arm which also moves left and right.
- the sample is moved against the top edge of the vane, moving the pendulum until a sample bends and releases it.
- the test is run in two steps, first to the left and then to the right.
- the scale reading is measured in each direction and the results are averaged.
- the instrument provides a relative flexibility measurement between the components of the outer tubular member as detailed below to achieve improved trackability and pushability.
- the outer tube 34 has a relatively stiff, proximal outer section 56 with a proximal end 60 and a distal end 62.
- the proximal outer tube may be made of nylon, a polyamide, such as DURETHAN available from Bayer, GRILAMID available from EMS-American Grilon, Inc., a DURETHAN, GRILAMID, CRISTAMID or CRISTAMID/VESTAMID blend braid or polyetheretherketone (PEEK) braid.
- PEEK braid is a variable PIC tube, wherein said PIC varies from about 30 to 100 PIC to give varying flexibility over the length of the proximal outer tube.
- the PIC preferably varies from about 50 to about 80.
- the braiding material in the PEEK or DURETHAN (polymer) braid may be made from stainless steel, or Nitinol (nickel titanium alloy).
- This proximal outer section 56 will have an outside diameter ranging from .040 inches to .065 inches with a wall thickness ranging from .0026 inches to .0056 inches.
- the proximal outer section has a preferred Gurley value of about 700 to about 1300 over its length. A preferred range is about 800 to about 1200.
- a midshaft section 58 with a proximal end 64 and a distal end 66 extends distally from the distal end 62 of the proximal outer section 56.
- the midshaft section 58 has a stiffness less than that of the proximal outer section 56.
- the midshaft section 58 is preferably made from a polyamide, such as CRISTAMID available from Elf Atochem, having a durometer of about 8 ID.
- a preferred Gurley value for the midsection is about 350 to about 500, with a range of 400 to 450 preferred.
- This midshaft section 58 will have an outside diameter ranging from .040 inches to .045 inches with a wall thickness ranging from .0028 inches to .0044 inches.
- the distal end of the proximal outer section 62 is joined to the proximal end of the midshaft section 64 with a urethane adhesive bond or a thermal weld.
- a distal outer section 68 having a proximal end 70 and a distal end 72 extends distally from the distal end of the midshaft section 66 to the distal end of the outer tube 44.
- This distal outer section 68 is more flexible or has less stiffness than both the proximal outer section 56 and the midshaft section 58.
- the outer diameter of the distal outer section 68 will taper from about .045 inches at the proximal end 70 to .030 inches at the distal end 72.
- This distal outer section 68 is made of polyether block amide (PEBAX) with a durometer of 70D.
- PEBAX polyether block amide
- the tapered distal outer section preferably has a Gurley value of about 70 to about 90 at its proximal end and about 15 to about 40 at its distal end.
- the distal end of the distal outer section 72 will exhibit less stiffness than the proximal end of the distal outer section 70.
- the distal end of the midshaft section 66 is joined to the proximal end of the distal outer section 70 with a urethane adhesive bond or a thermal weld.
- a Nitinol braid insert 74 with a length of about 1.0 inches is placed within the proximal end of the distal outer section 70 to provide strain relief and reduce kinkability at the midshaft/distal outer section junction.
- This Nitinol braid 74 has a .001 inches x .005 inches ribbon.
- the inner tube 28 is made of polyethylene such as Marlex HDPE or a multilayer co-extrusion with Marlex interior layer and PEBAX outer layer.
- the inner tube 28 has an outside diameter ranging from 0.022 inches to 0.028 inches and preferably about 0.025 inches, with the inner tube 28 having an inside diameter ranging from 0.016 inches to 0.021 inches for a 0.014 inch guidewire with which this lumen is designed to be compatible.
- the inner tube 28 has a wall thickness ranging from .0024 inches to .005 inches and preferably about .0032 inches.
- the outside diameter-to-wall thickness ratio must be sufficiently small to minimize the propensity of kinking.
- both the inner and outer diameters of the inner tube 28 will taper from wider diameters to narrower diameters.
- both the inner and outer diameters of the inner tube 28 will once again taper from wider diameters to narrower diameters as the tube extends distally.
- a distal tip 76 having a distal-most end 78 is formed on the distal end of the inner tube 32, where the inner tube 28 distally tapers from a larger outer diameter to a smaller outer diameter.
- the distal balloon waist 40 is attached to the distal tip 76 through a urethane adhesive bond or thermal bond at a bonding area.
- the area just distal of the distal waist bond is backfilled with adhesive 43 to provide a smooth transition.
- the adhesive coating provides for improved adhesion between dissimilar substrates.
- the proximal catheter shaft portion is preferably about 35 to 45 inches in length with a preferred length of 42 inches.
- the midshaft section if included, can be about 1 to about 3 inches in length with a preferred length of 2 inches.
- the distal outer section having the most flexibility is preferably about 8 to about 12 inches in length with a preferred length of about 10 inches.
- a polyethylene, polyamide, or block copolymer such as PEBAX distal tip 80 having a durometer between about 50D and 70D, preferably about 63D is heat welded or bonded to the distal end of the inner tube 32 with a durometer of about 63-65D, and the distal balloon waist 40 of the balloon is adhesively or thermally bonded to both the inner tube and the tip extending therefrom.
- the joint 41 between the inner tube and the tip is located under the distal waist of the balloon.
- the outer diameter of the polyethylene distal tip 80 distally tapers from a larger outer diameter to a smaller outer diameter.
- the last 1/2 to 1 mm of the tip at its distal end is made of a different material from the tip material to form a tip extension.
- the last 1/2 to 1 mm is made from a material which is more durable relative to the softer tip material.
- the more durable material will resist deforming or tearing when in use, such as in tracking tortuous anatomy or in moving through a deployed stent.
- this last 1/2 mm to 1 mm may be manufactured from Marlex high-density polyethylene having a 63D durometer which improves the integrity of the tip portion at its distal-most end 81.
- Figure 4 shows a preferred embodiment of a tip assembly which can be included in catheters such as that in Figures 1 and 3.
- radiopacity is provided to the tip assembly proximate its distal-most end by a radiopaque coil.
- Distal tip 76 is positioned distally from the distal balloon waist 40 of balloon 36.
- the distal tip is illustrated as having a coil 90 encircling the distal-most end 78.
- Coil 90 may be comprised of any radiopaque material.
- Preferable materials forming coil 90 include any metals or plastics being radiopaque, or capable of being impregnated with radiopaque materials.
- tungsten, tantalum, platinum, gold, and the like are examples of preferred materials forming coil 90.
- Coil 90 is preferably wire-shaped. Various shaped wires, however, may be used to form coil 90.
- coil 90 may be manufactured as a round wire, a wire ribbon, a cable wire, or a machined hypotube.
- the wire is wound about the distal tip 76, imparting a helical configuration to coil 90.
- Coil 90 may additionally encircle distal tip 76 through a series of connected spirals or concentric rings. In preferred embodiments, the windings of coil 90 terminate prior to reaching the distal-most end 78 of distal tip 76.
- the longitudinal spacing and tensile strength of the windings may vary from catheter to catheter.
- the physical characteristics of the distal tip 76 may be altered. For example, close spacing and elevated tensile strength often result in an increase in the stiffness of the distal tip 76, and more particularly, causing the distal-most end 78 to become less supple. Larger spacing and lower tensile strength, on the other hand, while still decreasing the flexibility of the distal tip 76 alone, retain a sufficiently supple distal-most end 78.
- FIG. 5 shows another preferred embodiment of a tip assembly in which radiopacity is contributed by a radiopaque mesh material.
- a radiopaque mesh 92 extends generally from distal balloon waist 40 of balloon 36 proximate distal-most end 78 of distal tip 76. Depending upon the flexibility desired for the catheter tip, the mesh can either encircle distal tip 76 entirely, or only a portion thereof. Alternatively, distal tip 76 can itself be fabricated of the radiopaque mesh material 92. When radiopaque mesh 92 is attached to the distal tip 76, the attachment generally occurs through the use of a urethane adhesive or thermal bond at the desired bonding location.
- a thermal bond permits embedding the radiopaque mesh 92 into the surrounding polymeric material forming distal tip 76. Embedding the mesh affords a manufacturer the option of eliminating the need to backfill the area just distal of the distal balloon waist 40.
- the embedding procedure itself provides a smooth transition along the distal tip 76.
- Backfilling when desired, is generally accomplished using an adhesive or other suitable polymeric material. Backfilling may additionally occur toward the distal-most end 78, or over the radiopaque mesh 92, to insure a smooth transition throughout the distal tip 76.
- a radiopaque braid can be used in place of the radiopaque mesh material.
- a polymeric material may be extruded over the radiopaque mesh or braid 92 forming a distal tip 76 having a lumen 54 extending longitudinally therein.
- FIGS 6A and 6B show another preferred embodiment of a tip assembly in which the radiopacity is provided by a radiopaque member or wire incorporated into the wall of the catheter tip.
- a radiopaque wire 94 shown in phantom in Figure 6A, is embedded in distal tip 76.
- Various shaped wires may be used to form wire 94.
- radiopaque wire 94 may be manufactured as a round wire, a wire ribbon, a cable wire, or a machined hypotube.
- Radiopaque wire 94 may be comprised of any radiopaque material.
- Materials forming radiopaque wire 94 include any metals or plastics being radiopaque or capable of being impregnated with radiopaque materials. In particular, tungsten, tantalum, platinum, gold, and the like, are examples of preferred materials forming radiopaque wire 94.
- Radiopaque wire 94 may originate anywhere within balloon distal waist 40 and extend longitudinally until terminating at or proximate the distal-most end 78 of distal tip 76.
- radiopaque wire 94 generally extends longitudinally from the proximal-most end of distal tip 76 and terminates prior to the distal-most end 78 thereof.
- the radiopaque wire 94 is preferably straight, however, the wire may additionally assume alternative configurations that follow a general longitudinal progression (e.g., a sinusoidal curve).
- Figure 6B shows a cross-section of the distal tip of Figure 6A having radiopaque wire 94 embedded therein.
- Lumen 50 is defined by an inner diameter and an outer diameter at the distal tip 76.
- the inner diameter defines a pathway for the passage of a guidewire.
- the outer diameter defines the surface of distal tip 76.
- Radiopaque wire 94 is positioned between the inner and outer diameters.
- radiopaque wire 94 is entirely encapsulated between the inner and outer diameter.
- FIG. 7 shows a radiopaque cap over the distal tip of the catheter.
- a radiopaque cap 96 surrounds distal tip 76, shown in phantom.
- Radiopaque cap 96 may be comprised of any radiopaque material. Materials forming radiopaque cap 96 include any metals or plastics being radiopaque or capable of being impregnated with radiopaque materials.
- radiopaque cap 96 is made of a high durometer polymeric material. Radiopaque caps of high durometer allow the distal tip region to remain supple, minimizing trauma associated with the catheter's advancement through the surrounding vessel walls.
- radiopaque cap 96 is formed independent from distal tip 76, the cap may be molded to redefine the original shape of the distal tip 76 of a catheter.
- radiopaque cap 96 may form a gradually decreasing taper from where cap 96 seats against balloon waist 40 to the cap's distal-most end. This cap configuration allows for a smooth transition between the distal tip region to the balloon region of a catheter.
- cap 96 may mimic the shape of a typical distal tip 76 having a straight tubular shape, as illustrated in Figure 7. Once the cap design is chosen and slid over the distal tip 76, the radiopaque cap 96 is preferably attached to distal tip 76 through a urethane adhesive or by thermal bonding.
- Figure 8A shows a half arc hypotube providing radiopacity to the distal-most end of the distal tip.
- Half arc hypotube 98 is securely attached to distal tip 76.
- the hypotube 98 may be attached anywhere along the length of distal tip 76. To aid a physician in pinpointing the distal-most end of the catheter, however, it is believed that the hypotube should be placed close to the distal-most end 78 of distal tip 76.
- hypotube 98 is attached to the outer diameter of the distal tip 76 through a urethane adhesive or by thermal bonding.
- Thermal bonding hypotube 98 to distal tip 76 permits the embedding of hypotube 98 into the polymeric material forming distal tip 76.
- the depth of the subsequent embedding may be varied.
- hypotube 98 is embedded into distal tip 76 until the outer diameter of hypotube 98 is flush with the outer diameter of distal tip 76.
- hypotube 98 may be partially embedded into the polymeric material forming distal tip 76. If desired, backfill of polymeric material may be added to smooth the transition around the exposed portions of hypotube 98.
- Figure 8B shows a cross-section of the distal tip 76 of Figure 8A having half arc hypotube 98 attached thereto.
- Lumen 54 is defined by an inner diameter and an outer diameter.
- the inner diameter defines a pathway for the passage of a guidewire.
- the outer diameter defines the outer surface of distal tip 76.
- hypotube 98 is attached directly upon the outer surface of distal tip 76. With this configuration, the edges of half arc hypotube 98 are exposed. Exposed edges may cause trauma to the surrounding vessel walls as the catheter is advanced. To alleviate this possibility for trauma, polymeric material may be added along these exposed edges to smooth the profile of distal tip 76.
- FIG 9 shows the distal tip embedded with radiopaque particles.
- Distal tip 76 is fabricated using a polymeric material impregnated with radiopaque particles 100.
- Radiopaque particles 100 may be in powder or particulate form. Any radiopaque material may be used that may be readily blended and extruded.
- Radiopaque particles 100 are preferably blended with a polymeric material capable of forming a soft distal tip 76. The blended material is then extruded to form an elongate distal tip 76 having a lumen 54 extending longitudinally therein.
- the resultant distal tip 76 may be either extruded simultaneously with the portions of the lumen forming the guidewire lumen, or the extruded distal tip 76 may be attached to the body of the catheter at a later time. If distal tip 76 is extruded independent of the main body of the catheter, the later attachment is preferably accomplished through a urethane adhesive or by thermal bonding. The distal tip may be assembled as described with reference to Figure 3.
- FIG 10 shows the use of a radiopaque pigment which is painted upon the distal tip.
- Radiopaque pigment 102 painted upon the distal tip allows identification of relevant portions on the catheter's body while within a vasculature.
- radiopaque pigment may be applied anywhere between the distal-most end 78 and balloon waist 40 of distal tip 76.
- Physicians may easily navigate and align a catheter across a stenosis or a stent when the physician accurately knows the location of the catheter's distal-most end 78. Additionally, when radiopaque pigment is applied to balloon waist 40, a physician may easily align the balloon within a stent. When a balloon is accurately positioned within a stent, on expansion, the stent opens with uniformity and with reduced trauma to the surrounding vasculature.
- radiopaque pigment 102 may be incorporated into a polymeric backfill.
- Backfill having radiopaque pigment 102 may be added to portions of distal tip 76.
- backfill may be added upon distal-most end 78 to readily identify the terminal point of the catheter.
- Figure 11 shows alternating bands of radiopaque material 104 incorporated within distal tip 76. Alternating hard radiopaque material with softer non-radiopaque material is possible. Bands 104 of radiopaque material may also alternate with bands 106 of non-radiopaque material throughout the length of distal tip 76. In an alternative embodiment, the radiopaque material is soft and the non-radiopaque material is hard. The alternating band configuration may additionally be applied to only a portion of distal tip 76, preferably, to the distal-most end.
- distal tip 76 Alternating bands of different durometers affects the flexibility of distal tip 76.
- This embodiment provides a more flexible and supple distal tip 76. During catheter advancement, this distal tip design permits aggressive navigation without traumatizing the surrounding vasculature.
- distal tip 76 is comprised wholly of a soft non- radiopaque material. Bands of material are then removed from the distal tip through an abrasion process. Specifically, the band of material is removed by bringing distal tip 76 into contact with a grinding wheel. The distal tip 76 is then rotated 360 degrees to remove the material circumferentially around the tip. The grinding wheel is slowly advanced to increase the depth of the cut. Although abrasion is the preferred method of processing, the band can be created using many different processes, some of which include alternate extrusion methods, cutting, and thermal processing. Material differing in durometer and radiopacity than the one removed from distal tip 76 is then backfilled into the exposed bands.
- the distal region of the catheter includes a balloon with a distal balloon waist 110 connected to the inner tube near its distal-most end.
- the distal-most end of the distal balloon waist 112 is connected to the inner tube by means of an adhesive bond or thermal bond. Adhesive or thermal bonding permits the interior of the balloon 36 to be in fluid communication with an annular inflation lumen.
- the distal balloon waist 110 extends proximally from the distal-most end along and slightly above the inner tube forming a narrow channel 114.
- the proximal end of the narrow channel 114 extends outwardly forming the distal end of balloon 36. As a result, the narrow channel 114 remains in fluid communication with balloon 36.
- the portion of distal balloon waist 110 forming the narrow channel 114 comprises a non-compliant balloon material.
- a reservoir of contrast media 108 is fluidly connected to balloon 36. The reservoir may dispense contrasting media 108 to balloon 36 when balloon 36 is either in an inflated or deflated state. When balloon 36 is supplied with contrasting media 108, the contrasting media 108 fills both the balloon 36 and the narrow channel 114 under the distal balloon waist 110.
- Visualization of the distal-most end of the narrow channel 114 is generally a close approximation of the distal-most end 78 of distal tip 76.
- a physician may accurately identify the catheter's positioning within the vasculature by adjusting for the known discrepancy between the distal-most end of the narrow channel 114 and the distal-most end 78 of distal tip 76.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01991631.1A EP1339355B1 (en) | 2000-12-08 | 2001-10-23 | Balloon catheter with radiopaque distal tip |
CA002431062A CA2431062C (en) | 2000-12-08 | 2001-10-23 | Balloon catheter with radiopaque distal tip |
JP2002547409A JP4709472B2 (en) | 2000-12-08 | 2001-10-23 | Balloon catheter with radiopaque tip |
AU2002231363A AU2002231363A1 (en) | 2000-12-08 | 2001-10-23 | Balloon catheter with radiopaque distal tip |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/733,355 | 2000-12-08 | ||
US09/733,355 US6623504B2 (en) | 2000-12-08 | 2000-12-08 | Balloon catheter with radiopaque distal tip |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002045622A2 true WO2002045622A2 (en) | 2002-06-13 |
WO2002045622A3 WO2002045622A3 (en) | 2002-12-05 |
Family
ID=24947269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/051106 WO2002045622A2 (en) | 2000-12-08 | 2001-10-23 | Balloon catheter with radiopaque distal tip |
Country Status (6)
Country | Link |
---|---|
US (1) | US6623504B2 (en) |
EP (1) | EP1339355B1 (en) |
JP (1) | JP4709472B2 (en) |
AU (1) | AU2002231363A1 (en) |
CA (1) | CA2431062C (en) |
WO (1) | WO2002045622A2 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005096797A1 (en) * | 2004-03-26 | 2005-10-20 | Boston Scientific Limited | Balloon catheter with radiopaque portion |
WO2006133958A1 (en) * | 2005-06-16 | 2006-12-21 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
JP2011212493A (en) * | 2005-03-03 | 2011-10-27 | Goodman Co Ltd | Balloon catheter |
US8323326B2 (en) | 2005-06-16 | 2012-12-04 | Angiomed GmbH & Co. Medizintechnik KG. | Catheter device |
US8535292B2 (en) | 2008-12-03 | 2013-09-17 | C. R. Bard, Inc. | Retractable catheter |
JP2016214820A (en) * | 2015-05-19 | 2016-12-22 | アボット カーディオバスキュラー システムズ インコーポレイテッド | Balloon catheter |
US9872785B2 (en) | 2005-06-16 | 2018-01-23 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
Families Citing this family (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5030358B2 (en) * | 2000-03-23 | 2012-09-19 | クック メディカル テクノロジーズ エルエルシー | Introducing sheath |
US7862541B2 (en) * | 2000-05-22 | 2011-01-04 | Abbott Laboratories Vascular Enterprises Limited | Catheter having a soft distal tip |
US7169161B2 (en) * | 2001-11-06 | 2007-01-30 | Possis Medical, Inc. | Guidewire having occlusive device and repeatably crimpable proximal end |
US20040236275A1 (en) * | 2003-05-20 | 2004-11-25 | Pruitt Sean R. | Catheter having a light emitting component |
US7208008B2 (en) * | 2003-10-02 | 2007-04-24 | Medtronic Vascular, Inc. | Balloonless direct stenting device |
US7341571B1 (en) | 2004-09-02 | 2008-03-11 | Advanced Cardiovascular Systems, Inc. | Balloon catheter having a multilayered distal tip |
US7744574B2 (en) | 2004-12-16 | 2010-06-29 | Boston Scientific Scimed, Inc. | Catheter tip to reduce wire lock |
ES2315947T3 (en) * | 2005-01-21 | 2009-04-01 | Abbott Laboratories Vascular Enterprises Limited | CATETER BALLOON THAT HAS A WHITE DISTAL POINT. |
US20060178696A1 (en) * | 2005-02-04 | 2006-08-10 | Porter Stephen C | Macroporous materials for use in aneurysms |
WO2006138741A1 (en) * | 2005-06-17 | 2006-12-28 | Abbott Laboratories | Method of reducing rigidity of angioplasty balloon sections |
US8551042B2 (en) * | 2005-09-12 | 2013-10-08 | Boston Scientific Scimed, Inc. | Tip with cavity for radiopaque filed adhesive |
US20070131317A1 (en) * | 2005-12-12 | 2007-06-14 | Accellent | Nickel-titanium alloy with a non-alloyed dispersion and methods of making same |
US7785317B2 (en) * | 2006-03-29 | 2010-08-31 | Codman & Shurtleff, Inc. | Joined metal tubing and method of manufacture |
US20080108974A1 (en) * | 2006-10-20 | 2008-05-08 | Vital Signs, Inc. | Reinforced catheter with radiopaque distal tip and process of manufacture |
US20100241178A1 (en) | 2008-06-02 | 2010-09-23 | Loma Vista Medical, Inc. | Inflatable medical devices |
WO2008095046A2 (en) | 2007-01-30 | 2008-08-07 | Loma Vista Medical, Inc., | Biological navigation device |
US8048471B2 (en) | 2007-12-21 | 2011-11-01 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
US7811623B2 (en) | 2007-12-21 | 2010-10-12 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
US8231926B2 (en) | 2007-12-21 | 2012-07-31 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
US7714217B2 (en) | 2007-12-21 | 2010-05-11 | Innovatech, Llc | Marked precoated strings and method of manufacturing same |
US8231927B2 (en) | 2007-12-21 | 2012-07-31 | Innovatech, Llc | Marked precoated medical device and method of manufacturing same |
US8951545B2 (en) | 2008-03-28 | 2015-02-10 | Surmodics, Inc. | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery |
US9364349B2 (en) | 2008-04-24 | 2016-06-14 | Surmodics, Inc. | Coating application system with shaped mandrel |
US9295820B2 (en) | 2008-08-14 | 2016-03-29 | Surmodics, Inc. | Method and apparatus for coating balloon catheters |
EP2424581B1 (en) | 2009-04-28 | 2017-03-01 | SurModics, Inc. | Devices and methods for delivery of bioactive agents |
ES2869953T3 (en) | 2010-02-09 | 2021-10-26 | Medinol Ltd | Spring Assembled Catheter Tip |
US10342570B2 (en) | 2014-02-03 | 2019-07-09 | Medinol Ltd. | Device for traversing vessel occlusions and method of use |
US8927000B2 (en) | 2010-06-30 | 2015-01-06 | Surmodics, Inc. | Lipid coating for medical devices delivering bioactive agent |
EP3552655B1 (en) | 2010-07-13 | 2020-12-23 | Loma Vista Medical, Inc. | Inflatable medical devices |
US10188436B2 (en) | 2010-11-09 | 2019-01-29 | Loma Vista Medical, Inc. | Inflatable medical devices |
WO2012096787A1 (en) | 2010-12-30 | 2012-07-19 | Surmodics, Inc. | Double wall catheter for delivering therapeutic agent |
US20120172796A1 (en) | 2010-12-30 | 2012-07-05 | Chappa Ralph A | Composition for intravascular delivery of therapeutic composition |
US8900652B1 (en) | 2011-03-14 | 2014-12-02 | Innovatech, Llc | Marked fluoropolymer surfaces and method of manufacturing same |
US10213529B2 (en) | 2011-05-20 | 2019-02-26 | Surmodics, Inc. | Delivery of coated hydrophobic active agent particles |
US9861727B2 (en) | 2011-05-20 | 2018-01-09 | Surmodics, Inc. | Delivery of hydrophobic active agent particles |
EP2714180B1 (en) | 2011-05-26 | 2018-11-07 | Abbott Cardiovascular Systems Inc. | Catheter with stepped skived hypotube |
JP2014521462A (en) | 2011-08-05 | 2014-08-28 | シルク・ロード・メディカル・インコーポレイテッド | Method and system for treating acute ischemic stroke |
CN104185491B (en) * | 2011-12-14 | 2016-08-10 | 东莞市迪凯精密管材有限公司 | The sacculus dilating catheter that soft cladding is most advanced and sophisticated is set |
BR112014017675B1 (en) | 2012-01-18 | 2021-06-22 | Surmodics, Inc | COATING FOR A LUBRICATING MEDICAL DEVICE WITH LOW PARTICULATE CONTENT, MEDICAL DEVICE AND METHOD OF PRODUCTION |
MX351261B (en) | 2012-06-01 | 2017-10-06 | Surmodics Inc | Apparatus and method for coating balloon catheters. |
US9827401B2 (en) | 2012-06-01 | 2017-11-28 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US9233015B2 (en) | 2012-06-15 | 2016-01-12 | Trivascular, Inc. | Endovascular delivery system with an improved radiopaque marker scheme |
US11090468B2 (en) | 2012-10-25 | 2021-08-17 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
WO2014066760A1 (en) | 2012-10-25 | 2014-05-01 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US11246963B2 (en) | 2012-11-05 | 2022-02-15 | Surmodics, Inc. | Compositions and methods for delivery of hydrophobic active agents |
JP6438406B2 (en) | 2012-11-05 | 2018-12-12 | サーモディクス,インコーポレイテッド | Compositions and methods for delivering hydrophobic bioactive agents |
US9283350B2 (en) | 2012-12-07 | 2016-03-15 | Surmodics, Inc. | Coating apparatus and methods |
JP6383732B2 (en) | 2013-01-04 | 2018-08-29 | サーモディクス,インコーポレイティド | Low particle lubricity coating with a layer containing vinylpyrrolidone polymer and acidic polymer |
US9545501B2 (en) * | 2013-03-06 | 2017-01-17 | Cook Medical Technologies Llc | System for a wire-lumen free balloon catheter |
US9358042B2 (en) | 2013-03-13 | 2016-06-07 | The Spectranetics Corporation | Expandable member for perforation occlusion |
US9427378B2 (en) * | 2013-04-30 | 2016-08-30 | Avent, Inc. | Gastric jejunal tube with an enlarged jejunal lumen |
CA2911482C (en) | 2013-05-07 | 2023-03-07 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
EP2994188A4 (en) | 2013-05-08 | 2017-03-29 | Embolx, Inc. | Device and methods for transvascular tumor embolization with integrated flow regulation |
WO2015075558A2 (en) * | 2013-11-25 | 2015-05-28 | Body Vision Medical Ltd. | Surgical devices and methods of use thereof |
US9789283B2 (en) | 2014-02-03 | 2017-10-17 | Medinol Ltd. | Catheter tip assembled with a spring |
US9918718B2 (en) | 2014-08-08 | 2018-03-20 | DePuy Synthes Products, Inc. | Embolic coil delivery system with retractable mechanical release mechanism |
CR20150461A (en) * | 2014-09-04 | 2015-12-14 | BALL CATHETER | |
US10426934B2 (en) * | 2014-09-04 | 2019-10-01 | Abbott Cardiovascular Systems Inc. | Balloon catheter |
US10124088B2 (en) | 2014-09-29 | 2018-11-13 | Surmodics, Inc. | Lubricious medical device elements |
CA2973625A1 (en) | 2015-01-14 | 2016-07-21 | Surmodics, Inc. | Insertion tools for medical device |
AU2016215229B2 (en) | 2015-02-04 | 2020-05-07 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system and method |
US11065019B1 (en) | 2015-02-04 | 2021-07-20 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
US10524809B2 (en) | 2015-02-26 | 2020-01-07 | Surmodics, Inc. | Insertable medical device system with plaque treatment portion and methods of using |
JP2016214821A (en) | 2015-05-19 | 2016-12-22 | アボット カーディオバスキュラー システムズ インコーポレイテッド | Catheter having monolithic multilayer distal outer member |
US10449336B2 (en) | 2015-08-11 | 2019-10-22 | The Spectranetics Corporation | Temporary occlusions balloon devices and methods for preventing blood flow through a vascular perforation |
US10499892B2 (en) | 2015-08-11 | 2019-12-10 | The Spectranetics Corporation | Temporary occlusion balloon devices and methods for preventing blood flow through a vascular perforation |
US10478546B2 (en) | 2015-09-15 | 2019-11-19 | Surmodics, Inc. | Hemodialysis catheter sleeve |
US11174447B2 (en) | 2015-12-29 | 2021-11-16 | Surmodics, Inc. | Lubricious coatings with surface salt groups |
US10342898B2 (en) | 2015-12-29 | 2019-07-09 | Surmodics, Inc. | Lubricious coatings with surface salt groups |
US9550046B1 (en) | 2016-02-16 | 2017-01-24 | Embolx, Inc. | Balloon catheter and methods of fabrication and use |
US11464948B2 (en) | 2016-02-16 | 2022-10-11 | Embolx, Inc. | Balloon catheters and methods of manufacture and use |
US10918835B2 (en) | 2016-03-31 | 2021-02-16 | Surmodics, Inc. | Delivery system for active agent coated balloon |
WO2017173121A1 (en) | 2016-03-31 | 2017-10-05 | Surmodics, Inc. | Drug-containing particulate composition with cationic agent, associated medical devices, and methods for treatment |
JP6947747B2 (en) | 2016-03-31 | 2021-10-13 | サーモディクス,インコーポレイティド | Lubricating coating for medical devices |
CN110198756B (en) | 2016-09-16 | 2022-07-12 | 舒尔默迪克斯公司 | Lubricious insertion tool for medical devices and methods of using same |
JP6754270B2 (en) * | 2016-10-21 | 2020-09-09 | テルモ株式会社 | Catheter assembly |
JP6754271B2 (en) * | 2016-10-21 | 2020-09-09 | テルモ株式会社 | Catheter assembly |
WO2018112196A1 (en) | 2016-12-16 | 2018-06-21 | Surmodics, Inc. | Hydrophobic active agent particle coatings and methods for treatment |
US10898446B2 (en) | 2016-12-20 | 2021-01-26 | Surmodics, Inc. | Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces |
CN114984407A (en) | 2017-01-10 | 2022-09-02 | 92号医疗公司 | System, catheter and catheter advancement device for performing medical procedures in intracranial vessels |
US10806462B2 (en) | 2017-12-21 | 2020-10-20 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with split tube and cylindrical coupling |
EP3793660A2 (en) | 2018-05-17 | 2021-03-24 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
WO2020112816A1 (en) | 2018-11-29 | 2020-06-04 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US11147562B2 (en) | 2018-12-12 | 2021-10-19 | DePuy Synthes Products, Inc. | Systems and methods for embolic implant detachment |
US11819590B2 (en) | 2019-05-13 | 2023-11-21 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US11253265B2 (en) | 2019-06-18 | 2022-02-22 | DePuy Synthes Products, Inc. | Pull wire detachment for intravascular devices |
US11207494B2 (en) * | 2019-07-03 | 2021-12-28 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant distal portion |
US11426174B2 (en) | 2019-10-03 | 2022-08-30 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant mechanical release |
US11439403B2 (en) | 2019-09-17 | 2022-09-13 | DePuy Synthes Products, Inc. | Embolic coil proximal connecting element and stretch resistant fiber |
US11376013B2 (en) | 2019-11-18 | 2022-07-05 | DePuy Synthes Products, Inc. | Implant delivery system with braid cup formation |
US11478815B2 (en) | 2020-01-16 | 2022-10-25 | Surmodics, Inc. | Coating systems for medical devices |
US11457922B2 (en) | 2020-01-22 | 2022-10-04 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant distal portion |
US11432822B2 (en) | 2020-02-14 | 2022-09-06 | DePuy Synthes Products, Inc. | Intravascular implant deployment system |
US11951026B2 (en) | 2020-06-30 | 2024-04-09 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with flexible braid section |
US11844490B2 (en) | 2021-12-30 | 2023-12-19 | DePuy Synthes Products, Inc. | Suture linkage for inhibiting premature embolic implant deployment |
US11937824B2 (en) | 2021-12-30 | 2024-03-26 | DePuy Synthes Products, Inc. | Implant detachment systems with a modified pull wire |
US11937825B2 (en) | 2022-03-02 | 2024-03-26 | DePuy Synthes Products, Inc. | Hook wire for preventing premature embolic implant detachment |
US11937826B2 (en) | 2022-03-14 | 2024-03-26 | DePuy Synthes Products, Inc. | Proximal link wire for preventing premature implant detachment |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047045A (en) | 1989-04-13 | 1991-09-10 | Scimed Life Systems, Inc. | Multi-section coaxial angioplasty catheter |
US5156594A (en) | 1990-08-28 | 1992-10-20 | Scimed Life Systems, Inc. | Balloon catheter with distal guide wire lumen |
US5891110A (en) | 1997-10-15 | 1999-04-06 | Scimed Life Systems, Inc. | Over-the-wire catheter with improved trackability |
Family Cites Families (143)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3911927A (en) | 1974-04-17 | 1975-10-14 | Princeton Biomedix | Eversible catheter |
US4085185A (en) | 1975-04-03 | 1978-04-18 | Adair Edwin Lloyd | Method of sealing concentric tube ends to make sealed dual-wall tube |
CH616337A5 (en) | 1977-10-21 | 1980-03-31 | Schneider Medintag Ag | |
US4323071A (en) | 1978-04-24 | 1982-04-06 | Advanced Catheter Systems, Inc. | Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same |
US4251305A (en) | 1978-11-01 | 1981-02-17 | Baxter Travenol Laboratories, Inc. | Method of radiant heat sealing of a balloon onto a catheter employing tinted shrink tubing |
US4249536A (en) | 1979-05-14 | 1981-02-10 | Vega Roger E | Urological catheter |
US4307722A (en) | 1979-08-14 | 1981-12-29 | Evans Joseph M | Dilators for arterial dilation |
US4385635A (en) | 1980-04-25 | 1983-05-31 | Ruiz Oscar F | Angiographic catheter with soft tip end |
US4588399A (en) | 1980-05-14 | 1986-05-13 | Shiley Incorporated | Cannula with radiopaque tip |
US4413989A (en) | 1980-09-08 | 1983-11-08 | Angiomedics Corporation | Expandable occlusion apparatus |
US4531512A (en) | 1981-06-15 | 1985-07-30 | Datascope Corporation | Wrapping system for intra-aortic balloon utilizing a wrapping envelope |
US4425919A (en) | 1981-07-27 | 1984-01-17 | Raychem Corporation | Torque transmitting catheter apparatus |
US4540404A (en) | 1983-01-19 | 1985-09-10 | Datascope Corp. | Balloon catheter with intrinsic introducer for percutaneous insertion into a blood vessel over a guide wire, and method of use |
US4596563A (en) | 1983-06-09 | 1986-06-24 | Cordis Corporation | Thin-walled multi-layered catheter having a fuseless tip |
US4531943A (en) | 1983-08-08 | 1985-07-30 | Angiomedics Corporation | Catheter with soft deformable tip |
US4571240A (en) | 1983-08-12 | 1986-02-18 | Advanced Cardiovascular Systems, Inc. | Catheter having encapsulated tip marker |
USRE33166E (en) | 1983-08-12 | 1990-02-20 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US4764324A (en) | 1983-12-12 | 1988-08-16 | Warren Burnham | Method of making a catheter |
US4636346A (en) | 1984-03-08 | 1987-01-13 | Cordis Corporation | Preparing guiding catheter |
US4753765A (en) | 1984-03-08 | 1988-06-28 | Cordis Corporation | Method of making a catheter having a fuseless tip |
US4551292A (en) | 1984-04-05 | 1985-11-05 | Angiomedics, Inc. | Method for making a catheter with a soft, deformable tip |
US4646719A (en) | 1984-06-11 | 1987-03-03 | Aries Medical Incorporated | Intra-aortic balloon catheter having flexible torque transmitting tube |
GB8415265D0 (en) | 1984-06-15 | 1984-07-18 | Ici Plc | Device |
US4636272A (en) | 1985-02-19 | 1987-01-13 | Cordis Corporation | Process for thermally bonding plastic tubes |
US4706670A (en) | 1985-11-26 | 1987-11-17 | Meadox Surgimed A/S | Dilatation catheter |
JPH0790042B2 (en) | 1985-09-20 | 1995-10-04 | レイケム・コ−ポレイション | Guiding category |
US4921483A (en) | 1985-12-19 | 1990-05-01 | Leocor, Inc. | Angioplasty catheter |
US4676229A (en) | 1986-04-09 | 1987-06-30 | Welch Allyn, Inc. | Biopsy channel for an endoscope |
US4739768B2 (en) | 1986-06-02 | 1995-10-24 | Target Therapeutics Inc | Catheter for guide-wire tracking |
US4759748A (en) | 1986-06-30 | 1988-07-26 | Raychem Corporation | Guiding catheter |
US4886506A (en) | 1986-12-23 | 1989-12-12 | Baxter Travenol Laboratories, Inc. | Soft tip catheter |
US4976720A (en) | 1987-01-06 | 1990-12-11 | Advanced Cardiovascular Systems, Inc. | Vascular catheters |
US4748982A (en) | 1987-01-06 | 1988-06-07 | Advanced Cardiovascular Systems, Inc. | Reinforced balloon dilatation catheter with slitted exchange sleeve and method |
US4782834A (en) | 1987-01-06 | 1988-11-08 | Advanced Cardiovascular Systems, Inc. | Dual lumen dilatation catheter and method of manufacturing the same |
JPS63212374A (en) | 1987-02-27 | 1988-09-05 | テルモ株式会社 | Catheter equipped with expander |
US4817613A (en) | 1987-07-13 | 1989-04-04 | Devices For Vascular Intervention, Inc. | Guiding catheter |
US4863442A (en) | 1987-08-14 | 1989-09-05 | C. R. Bard, Inc. | Soft tip catheter |
US4820349A (en) | 1987-08-21 | 1989-04-11 | C. R. Bard, Inc. | Dilatation catheter with collapsible outer diameter |
US4808164A (en) | 1987-08-24 | 1989-02-28 | Progressive Angioplasty Systems, Inc. | Catheter for balloon angioplasty |
US5159937A (en) | 1987-09-30 | 1992-11-03 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US5050606A (en) | 1987-09-30 | 1991-09-24 | Advanced Cardiovascular Systems, Inc. | Method for measuring pressure within a patient's coronary artery |
US4964409A (en) | 1989-05-11 | 1990-10-23 | Advanced Cardiovascular Systems, Inc. | Flexible hollow guiding member with means for fluid communication therethrough |
US4819751A (en) | 1987-10-16 | 1989-04-11 | Baxter Travenol Laboratories, Inc. | Valvuloplasty catheter and method |
FR2622197B1 (en) | 1987-10-21 | 1990-03-09 | Atochem | TRANSPARENT POLYAMIDES, THEIR MANUFACTURING PROCESS |
JPH01145074A (en) | 1987-12-01 | 1989-06-07 | Terumo Corp | Balloon catheter |
US4943278A (en) | 1988-02-29 | 1990-07-24 | Scimed Life Systems, Inc. | Dilatation balloon catheter |
US4884573A (en) | 1988-03-07 | 1989-12-05 | Leocor, Inc. | Very low profile angioplasty balloon catheter with capacity to use steerable, removable guidewire |
US5078702A (en) | 1988-03-25 | 1992-01-07 | Baxter International Inc. | Soft tip catheters |
US4950239A (en) | 1988-08-09 | 1990-08-21 | Worldwide Medical Plastics Inc. | Angioplasty balloons and balloon catheters |
US4998923A (en) | 1988-08-11 | 1991-03-12 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US4906244A (en) | 1988-10-04 | 1990-03-06 | Cordis Corporation | Balloons for medical devices and fabrication thereof |
US5156612A (en) | 1988-10-04 | 1992-10-20 | Cordis Corporation | Balloons for medical devices and fabrication thereof |
US4955377A (en) | 1988-10-28 | 1990-09-11 | Lennox Charles D | Device and method for heating tissue in a patient's body |
US4917666A (en) | 1988-11-14 | 1990-04-17 | Medtronic Versaflex, Inc. | Steerable thru-lumen catheter |
US5147377A (en) | 1988-11-23 | 1992-09-15 | Harvinder Sahota | Balloon catheters |
JP2554733B2 (en) | 1989-01-20 | 1996-11-13 | 積水化学工業株式会社 | Resin tube joining method |
US4960410A (en) | 1989-03-31 | 1990-10-02 | Cordis Corporation | Flexible tubular member for catheter construction |
US5100381A (en) | 1989-11-13 | 1992-03-31 | Scimed Life Systems, Inc. | Angioplasty catheter |
US5120308A (en) | 1989-05-03 | 1992-06-09 | Progressive Angioplasty Systems, Inc. | Catheter with high tactile guide wire |
US4955862A (en) | 1989-05-22 | 1990-09-11 | Target Therapeutics, Inc. | Catheter and catheter/guide wire device |
US4994018A (en) | 1989-05-31 | 1991-02-19 | Datascope Corporation | Intra-aortic balloon assembly |
GB8916158D0 (en) | 1989-07-14 | 1989-08-31 | Smiths Industries Plc | Catheters |
DE69002295T2 (en) | 1989-09-25 | 1993-11-04 | Schneider Usa Inc | MULTILAYER EXTRUSION AS A METHOD FOR PRODUCING BALLOONS FOR VESSEL PLASTICS. |
US5318532A (en) | 1989-10-03 | 1994-06-07 | C. R. Bard, Inc. | Multilumen catheter with variable cross-section lumens |
US5209728B1 (en) | 1989-11-02 | 1998-04-14 | Danforth Biomedical Inc | Low profile high performance interventional catheters |
US5324263A (en) | 1989-11-02 | 1994-06-28 | Danforth Biomedical, Inc. | Low profile high performance interventional catheters |
US5256144A (en) | 1989-11-02 | 1993-10-26 | Danforth Biomedical, Inc. | Low profile, high performance interventional catheters |
US5002559A (en) | 1989-11-30 | 1991-03-26 | Numed | PTCA catheter |
JP2528011B2 (en) | 1989-12-20 | 1996-08-28 | テルモ株式会社 | Catheter |
EP0472716A1 (en) | 1990-03-16 | 1992-03-04 | Medtronic, Inc. | Dilatation catheter |
US5078700A (en) | 1990-03-19 | 1992-01-07 | Becton, Dickinson And Company | Liquid crystalline catheter |
IE67657B1 (en) | 1990-03-26 | 1996-04-17 | Becton Dickinson Co | Catheter tubing of controlled in vivo softening |
US5176637A (en) | 1990-04-19 | 1993-01-05 | Terumo Kabushiki Kaisha | Catheter equipped with a dilation element |
JP2516453B2 (en) | 1990-04-19 | 1996-07-24 | テルモ株式会社 | Caterer with extension body |
US5122125A (en) | 1990-04-25 | 1992-06-16 | Ashridge A.G. | Catheter for angioplasty with soft centering tip |
US5158548A (en) | 1990-04-25 | 1992-10-27 | Advanced Cardiovascular Systems, Inc. | Method and system for stent delivery |
EP0527969A1 (en) | 1990-05-11 | 1993-02-24 | SAAB, Mark, A. | High-strength, thin-walled single piece catheters |
US5217482A (en) | 1990-08-28 | 1993-06-08 | Scimed Life Systems, Inc. | Balloon catheter with distal guide wire lumen |
JPH05506174A (en) | 1990-09-14 | 1993-09-16 | アメリカン・メディカル・システムズ・インコーポレーテッド | Combined hyperthermia and dilatation catheter |
US5423754A (en) | 1990-09-20 | 1995-06-13 | Scimed Life Systems, Inc. | Intravascular catheter |
US5143093A (en) | 1990-10-05 | 1992-09-01 | Harvinder Sahota | Methods of angioplasty treatment of stenotic regions |
US5246420A (en) * | 1990-11-19 | 1993-09-21 | Danforth Biomedical Incorporated | Highly steerable dilatation balloon catheter system |
US5139496A (en) | 1990-12-20 | 1992-08-18 | Hed Aharon Z | Ultrasonic freeze ablation catheters and probes |
US5254091A (en) | 1991-01-08 | 1993-10-19 | Applied Medical Resources Corporation | Low profile balloon catheter and method for making same |
US5234416A (en) | 1991-06-06 | 1993-08-10 | Advanced Cardiovascular Systems, Inc. | Intravascular catheter with a nontraumatic distal tip |
US5154725A (en) | 1991-06-07 | 1992-10-13 | Advanced Cardiovascular Systems, Inc. | Easily exchangeable catheter system |
US5221270A (en) | 1991-06-28 | 1993-06-22 | Cook Incorporated | Soft tip guiding catheter |
US5240537A (en) | 1991-07-01 | 1993-08-31 | Namic U.S.A. Corporation | Method for manufacturing a soft tip catheter |
JPH09507391A (en) | 1991-07-24 | 1997-07-29 | アドヴァンスト・カーディオヴァスキュラー・システムズ・インコーポレイテッド | Low profile perfusion dilatation catheter |
US5180585A (en) | 1991-08-09 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Antimicrobial compositions, process for preparing the same and use |
JP2627988B2 (en) | 1991-08-21 | 1997-07-09 | 三菱電線工業株式会社 | Method and apparatus for manufacturing rigid inclined long body |
US5259839A (en) | 1991-08-23 | 1993-11-09 | Scimed Life Systems, Inc. | Balloon catheter with guidewire valve |
US5213574A (en) | 1991-09-06 | 1993-05-25 | Device Labs, Inc. | Composite implantable biocompatible vascular access port device |
US5389087A (en) | 1991-09-19 | 1995-02-14 | Baxter International Inc. | Fully exchangeable over-the-wire catheter with rip seam and gated side port |
JP3053029B2 (en) | 1991-10-08 | 2000-06-19 | テルモ株式会社 | Vascular dilatation catheter balloon |
US5226888A (en) | 1991-10-25 | 1993-07-13 | Michelle Arney | Coiled, perfusion balloon catheter |
US5171230A (en) | 1991-11-29 | 1992-12-15 | Medex, Inc. | Fast flush catheter valve |
US5324259A (en) | 1991-12-18 | 1994-06-28 | Advanced Cardiovascular Systems, Inc. | Intravascular catheter with means to seal guidewire port |
US5304134A (en) | 1992-01-17 | 1994-04-19 | Danforth Biomedical, Inc. | Lubricious yet bondable catheter channel sleeve for over-the-wire catheters |
CA2060133C (en) | 1992-01-30 | 2002-05-28 | Geoffrey S. Martin | Balloon catheter |
US5318032A (en) | 1992-02-05 | 1994-06-07 | Devices For Vascular Intervention | Guiding catheter having soft tip |
US5944712A (en) | 1992-03-02 | 1999-08-31 | Medtronic Ave, Inc. | Catheter size designation system |
WO1993018816A1 (en) * | 1992-03-17 | 1993-09-30 | Scimed Life Systems, Inc. | Balloon dilatation catheter having a free core wire |
US5344400A (en) | 1992-04-06 | 1994-09-06 | Terumo Kabushiki Kaisha | Balloon catheters containing molded polyarylenesulfide material |
US5399164A (en) | 1992-11-02 | 1995-03-21 | Catheter Imaging Systems | Catheter having a multiple durometer |
US5316706A (en) | 1992-08-05 | 1994-05-31 | Advanced Cardiovascular Systems | Method of manufacturing jointless catheter |
JP3310031B2 (en) | 1992-10-23 | 2002-07-29 | テルモ株式会社 | Catheter tube |
US5342386A (en) | 1992-10-26 | 1994-08-30 | Cordis Corporation | Catheter with multiple flexibilities along the shaft |
US5304198A (en) | 1992-11-13 | 1994-04-19 | Target Therapeutics | Single-lumen balloon catheter having a directional valve |
US5549556A (en) | 1992-11-19 | 1996-08-27 | Medtronic, Inc. | Rapid exchange catheter with external wire lumen |
US5318527A (en) | 1992-12-22 | 1994-06-07 | Advanced Cardiovascular Systems, Inc. | Fixed wire catheter exchange device |
US5370615A (en) | 1992-12-28 | 1994-12-06 | Cordis Corporation | Balloon catheter for angioplasty |
JPH06237986A (en) | 1993-02-15 | 1994-08-30 | Terumo Corp | Tube transporting device |
US5335410A (en) | 1993-03-15 | 1994-08-09 | Burnham Warren R | Method of making ultra small diameter catheters and of reinforced tubular product |
ATE168892T1 (en) | 1993-04-09 | 1998-08-15 | Schneider Usa Inc | DILATION CATHETER WITH A SOFT BUFFER TIP |
US5531715A (en) | 1993-05-12 | 1996-07-02 | Target Therapeutics, Inc. | Lubricious catheters |
US5334168A (en) | 1993-06-11 | 1994-08-02 | Catheter Research, Inc. | Variable shape guide apparatus |
WO1995002430A1 (en) | 1993-07-15 | 1995-01-26 | Advanced Cardiovascular Systems, Inc. | Rapid exchange type intraluminal catheter with guiding element |
US5425709A (en) | 1993-07-22 | 1995-06-20 | C. R. Bard, Inc. | Sheath for a balloon catheter |
US5405338A (en) | 1993-08-19 | 1995-04-11 | Cordis Corporation | Helically wound catheters |
JPH07178176A (en) | 1993-12-24 | 1995-07-18 | Terumo Corp | Catheter |
US5387193A (en) | 1994-02-09 | 1995-02-07 | Baxter International Inc. | Balloon dilation catheter with hypotube |
US5569218A (en) | 1994-02-14 | 1996-10-29 | Scimed Life Systems, Inc. | Elastic guide catheter transition element |
AU685575B2 (en) | 1994-03-10 | 1998-01-22 | Schneider (Usa) Inc. | Catheter having shaft of varying stiffness |
US5470322A (en) | 1994-04-15 | 1995-11-28 | Danforth Biomedical Inc. | Reinforced multilumen catheter for axially varying stiffness |
US5509910A (en) | 1994-05-02 | 1996-04-23 | Medtronic, Inc. | Method of soft tip attachment for thin walled catheters |
US5403292A (en) | 1994-05-18 | 1995-04-04 | Schneider (Usa) Inc. | Thin wall catheter having enhanced torqueability characteristics |
US5480383A (en) | 1994-05-27 | 1996-01-02 | Advanced Cardiovascular Systems, Inc. | Dilation catheter with a smooth transition between a stiff proximal portion and a flexible distal portion |
JP3970341B2 (en) | 1994-06-20 | 2007-09-05 | テルモ株式会社 | Vascular catheter |
US5542937A (en) | 1994-06-24 | 1996-08-06 | Target Therapeutics, Inc. | Multilumen extruded catheter |
US5454795A (en) | 1994-06-27 | 1995-10-03 | Target Therapeutics, Inc. | Kink-free spiral-wound catheter |
US5496294A (en) | 1994-07-08 | 1996-03-05 | Target Therapeutics, Inc. | Catheter with kink-resistant distal tip |
US5554121B1 (en) | 1994-07-25 | 1998-07-14 | Advanced Cardiovascular System | Intraluminal catheter with high strength proximal shaft |
US5540236A (en) | 1994-08-05 | 1996-07-30 | Cardiovascular Imaging Systems, Incorporated | Guide wire exit port |
JPH10509616A (en) | 1994-11-23 | 1998-09-22 | マイクロ インターベンショナル システムズ インコーポレーテッド | High torque balloon catheter |
US5549552A (en) | 1995-03-02 | 1996-08-27 | Scimed Life Systems, Inc. | Balloon dilation catheter with improved pushability, trackability and crossability |
US5645528A (en) | 1995-06-06 | 1997-07-08 | Urologix, Inc. | Unitary tip and balloon for transurethral catheter |
JPH09639A (en) | 1995-06-23 | 1997-01-07 | New Ueebu Medical:Kk | Coronary vein expander for ptca surgery |
US5716373A (en) | 1995-07-19 | 1998-02-10 | Datascope Investment Corp. | Support member for reduced diameter balloon catheter, and intra-aortic balloon catheter using the same |
US5843050A (en) | 1995-11-13 | 1998-12-01 | Micro Therapeutics, Inc. | Microcatheter |
US5643209A (en) | 1995-12-15 | 1997-07-01 | Medtronic, Inc. | High pressure balloon tip |
US6048338A (en) | 1997-10-15 | 2000-04-11 | Scimed Life Systems, Inc. | Catheter with spiral cut transition member |
WO1999048548A1 (en) * | 1998-03-23 | 1999-09-30 | Medtronic, Inc. | Catheter having extruded radiopaque stripes embedded in soft tip and method of fabrication |
-
2000
- 2000-12-08 US US09/733,355 patent/US6623504B2/en not_active Expired - Lifetime
-
2001
- 2001-10-23 WO PCT/US2001/051106 patent/WO2002045622A2/en active Application Filing
- 2001-10-23 AU AU2002231363A patent/AU2002231363A1/en not_active Abandoned
- 2001-10-23 CA CA002431062A patent/CA2431062C/en not_active Expired - Fee Related
- 2001-10-23 EP EP01991631.1A patent/EP1339355B1/en not_active Expired - Lifetime
- 2001-10-23 JP JP2002547409A patent/JP4709472B2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047045A (en) | 1989-04-13 | 1991-09-10 | Scimed Life Systems, Inc. | Multi-section coaxial angioplasty catheter |
US5156594A (en) | 1990-08-28 | 1992-10-20 | Scimed Life Systems, Inc. | Balloon catheter with distal guide wire lumen |
US5891110A (en) | 1997-10-15 | 1999-04-06 | Scimed Life Systems, Inc. | Over-the-wire catheter with improved trackability |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005096797A1 (en) * | 2004-03-26 | 2005-10-20 | Boston Scientific Limited | Balloon catheter with radiopaque portion |
JP2011212493A (en) * | 2005-03-03 | 2011-10-27 | Goodman Co Ltd | Balloon catheter |
WO2006133958A1 (en) * | 2005-06-16 | 2006-12-21 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
US8323326B2 (en) | 2005-06-16 | 2012-12-04 | Angiomed GmbH & Co. Medizintechnik KG. | Catheter device |
US8758420B2 (en) | 2005-06-16 | 2014-06-24 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
US9615950B2 (en) | 2005-06-16 | 2017-04-11 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
US9872785B2 (en) | 2005-06-16 | 2018-01-23 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
US10596020B2 (en) | 2005-06-16 | 2020-03-24 | Angiomed Gmbh & Co. Medizintechnik Kg | Catheter device |
US8535292B2 (en) | 2008-12-03 | 2013-09-17 | C. R. Bard, Inc. | Retractable catheter |
JP2016214820A (en) * | 2015-05-19 | 2016-12-22 | アボット カーディオバスキュラー システムズ インコーポレイテッド | Balloon catheter |
Also Published As
Publication number | Publication date |
---|---|
US6623504B2 (en) | 2003-09-23 |
AU2002231363A1 (en) | 2002-06-18 |
JP4709472B2 (en) | 2011-06-22 |
EP1339355B1 (en) | 2017-06-28 |
CA2431062C (en) | 2010-03-09 |
US20020072705A1 (en) | 2002-06-13 |
WO2002045622A3 (en) | 2002-12-05 |
EP1339355A2 (en) | 2003-09-03 |
JP2005511108A (en) | 2005-04-28 |
CA2431062A1 (en) | 2002-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1339355B1 (en) | Balloon catheter with radiopaque distal tip | |
US7115183B2 (en) | Catheter with spiral cut transition member | |
US5891110A (en) | Over-the-wire catheter with improved trackability | |
US6113579A (en) | Catheter tip designs and methods for improved stent crossing | |
EP1284779B1 (en) | Catheter with improved transition | |
US6193686B1 (en) | Catheter with enhanced flexibility | |
US6837870B2 (en) | Catheter having a multilayered shaft section with a reinforcing mandrel | |
US6702802B1 (en) | Catheters with improved transition | |
EP1094861B1 (en) | Catheter tip designs for improved stent crossing | |
US6612998B2 (en) | Guide wire with marker sleeve | |
US20120203172A1 (en) | Catheter having a soft distal tip | |
WO2003024498A1 (en) | Catheter with a multilayered shaft section having a polyimide layer | |
CA2016498A1 (en) | Dilatation catheter suitable for peripheral arteries | |
US20030208221A1 (en) | Catheter with a coiled support member |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2002231363 Country of ref document: AU Ref document number: 2002547409 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2431062 Country of ref document: CA |
|
REEP | Request for entry into the european phase |
Ref document number: 2001991631 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2001991631 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2001991631 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |