WO2002040998A3 - Kit und verfahren zur multianalytbestimmung - Google Patents

Kit und verfahren zur multianalytbestimmung Download PDF

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Publication number
WO2002040998A3
WO2002040998A3 PCT/EP2001/012790 EP0112790W WO0240998A3 WO 2002040998 A3 WO2002040998 A3 WO 2002040998A3 EP 0112790 W EP0112790 W EP 0112790W WO 0240998 A3 WO0240998 A3 WO 0240998A3
Authority
WO
WIPO (PCT)
Prior art keywords
kit
analytes
determining multiple
multiple analytes
detection elements
Prior art date
Application number
PCT/EP2001/012790
Other languages
English (en)
French (fr)
Other versions
WO2002040998A2 (de
Inventor
Andreas P Abel
Gerhard M Kresbach
Gert L Duveneck
Nania G Schaerer-Hernandez
Original Assignee
Zeptosens Ag
Andreas P Abel
Gerhard M Kresbach
Gert L Duveneck
Nania G Schaerer-Hernandez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeptosens Ag, Andreas P Abel, Gerhard M Kresbach, Gert L Duveneck, Nania G Schaerer-Hernandez filed Critical Zeptosens Ag
Priority to US10/416,757 priority Critical patent/US20040058385A1/en
Priority to EP01994637A priority patent/EP1334361A2/de
Priority to AU2002224831A priority patent/AU2002224831A1/en
Publication of WO2002040998A2 publication Critical patent/WO2002040998A2/de
Publication of WO2002040998A3 publication Critical patent/WO2002040998A3/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

Die Erfindung betrifft verschiedene Ausführungsformen eines Kits zum gleichzeitigen qualitativen und/oder quantitativen Nachweis einer Vielzahl von Analyten, welcher es insbesondere ermöglicht, die Dichte der zum Nachweis besagter Analyten immobilisierten biologischen oder biochemischen oder synthetischen Erkennungselemente, d.h. die Belegungsdichte der für diese Erkennungselemente ausgewiesenen Messbereiche, zu referenzieren. Die Erfindung betrifft auch auf dem erfindungsgemässen Kit basierende analytische Systeme sowie damit durchgeführte Verfahren zum Nachweis eines oder mehrerer Analyten und deren Verwendung.
PCT/EP2001/012790 2000-11-17 2001-11-05 Kit und verfahren zur multianalytbestimmung WO2002040998A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/416,757 US20040058385A1 (en) 2000-11-17 2001-11-05 Kit and method for determining multiple analytes, with provisions for refrencing the density of immobilised recognition elements
EP01994637A EP1334361A2 (de) 2000-11-17 2001-11-05 Kit und verfahren zur multianalytbestimmung, mit vorkehrungen zur referenzierung der dichte immobilisierter erkennungselemente
AU2002224831A AU2002224831A1 (en) 2000-11-17 2001-11-05 Kit and method for determining multiple analytes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH22442000 2000-11-17
CH2244/00 2000-11-17

Publications (2)

Publication Number Publication Date
WO2002040998A2 WO2002040998A2 (de) 2002-05-23
WO2002040998A3 true WO2002040998A3 (de) 2003-05-22

Family

ID=4568186

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012790 WO2002040998A2 (de) 2000-11-17 2001-11-05 Kit und verfahren zur multianalytbestimmung

Country Status (4)

Country Link
US (1) US20040058385A1 (de)
EP (1) EP1334361A2 (de)
AU (1) AU2002224831A1 (de)
WO (1) WO2002040998A2 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10208770A1 (de) * 2002-02-28 2003-09-04 Febit Ag Erhöhung der Sensitivität und Spezifität von Hybridisierungsexperimenten mit Nukleinsäure-Chips
US7223368B2 (en) * 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7771922B2 (en) 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7214530B2 (en) * 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
US7485453B2 (en) * 2002-05-03 2009-02-03 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
WO2003096018A2 (de) * 2002-05-13 2003-11-20 Zeptosens Ag Kit zur assay-entwicklung und für serien-analysen
US7091049B2 (en) * 2002-06-26 2006-08-15 Kimberly-Clark Worldwide, Inc. Enhanced diffraction-based biosensor devices
AU2003298412A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and identification method
AU2003258683A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and detection method with analytes which are to be detected in a sample in the form of immobilized specific binding partners
US7545494B2 (en) * 2003-07-23 2009-06-09 Bayer Technology Services Gmbh Analytical system and method for analyzing nonlinear optical signals
JP2006010391A (ja) * 2004-06-23 2006-01-12 Olympus Corp 生体関連物質用試験片の製造方法、及び試験装置
JP2006105803A (ja) * 2004-10-06 2006-04-20 Hitachi High-Technologies Corp 生体試料物質の分析方法、分析装置、マイクロアレイ及びイムノアッセイ
DE102005026839A1 (de) * 2005-06-10 2006-12-21 Universität Tübingen Verfahren und Vorrichtung zur quantitativen Bestimmung von Analyten in flüssigen Proben
US7494776B2 (en) * 2005-07-07 2009-02-24 Beckman Coulter, Inc. Labeled complementary oligonucleotides to detect oligonucleotide-linked ligands
US7927948B2 (en) 2005-07-20 2011-04-19 Micron Technology, Inc. Devices with nanocrystals and methods of formation
US7575978B2 (en) * 2005-08-04 2009-08-18 Micron Technology, Inc. Method for making conductive nanoparticle charge storage element
US7989290B2 (en) * 2005-08-04 2011-08-02 Micron Technology, Inc. Methods for forming rhodium-based charge traps and apparatus including rhodium-based charge traps
EP2269724A1 (de) 2005-10-29 2011-01-05 Bayer Technology Services GmbH Verfahren zur Bestimmung eines oder mehrerer Analyten in komplex zusammengesetzten Proben biologischen Ursprungs und dessen Verwendung
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US8367506B2 (en) 2007-06-04 2013-02-05 Micron Technology, Inc. High-k dielectrics with gold nano-particles
US8728025B2 (en) 2008-03-10 2014-05-20 S.E.A. Medical Systems, Inc. Intravenous fluid monitoring
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
EP2425286B1 (de) 2009-04-29 2020-06-24 Ldip, Llc Auf wellenleitern basierendes detektionssystem mit abtastlichtquelle
US9052276B2 (en) 2009-06-08 2015-06-09 S.E.A. Medical Systems, Inc. Systems and methods for the identification of compounds using admittance spectroscopy
WO2011030318A1 (en) * 2009-09-14 2011-03-17 Koninklijke Philips Electronics N.V. Sensing system for sensing a substance in a fluid
WO2012006995A1 (de) * 2010-07-12 2012-01-19 Nanospot Gmbh Mikrostrukturierter messchip zur optischen messung von eigenschaften künstlicher oder biologischer membranen und verfahren zu dessen herstellung
DE202011106093U1 (de) * 2011-09-24 2011-10-19 Euroimmun Medizinische Labordiagnostika Ag Kalibrationsstreifen für einen Immunoblot
US9110001B2 (en) 2012-07-02 2015-08-18 Thermo Scientific Portable Analytical Instruments Inc. Method for tagging reference materials of interest in spectroscopic searching applications
US9753042B2 (en) * 2013-04-23 2017-09-05 Rosalind Franklin University Of Medicine And Science Kits for determining male fertility by measuring levels of a2V-ATPase, G-CSF, MIP 1 alpha, MCP-1, and methods and kits for improving reproductive outcomes in artificial insemination procedures
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
WO2016138427A1 (en) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US9696259B2 (en) * 2015-08-18 2017-07-04 Lumasense Technologies Holdings, Inc. Optode sensor with integrated reference
CN109932513B (zh) * 2019-03-04 2020-09-29 浙江大学 Rppa和pwg在制备呼吸道病原体检测制品中的应用
WO2023154909A1 (en) * 2022-02-14 2023-08-17 Cz Biohub Sf, Llc A tunable proximity assay that can overcome dilutional non-linearity

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0789242A2 (de) * 1996-02-06 1997-08-13 Roche Diagnostics GmbH Werkstoffe und Verfahren für Bindungsassays
WO1998008077A1 (de) * 1996-08-16 1998-02-26 Novartis Ag Optische detektionsvorrichtung
WO1998009156A1 (en) * 1996-08-29 1998-03-05 Novartis Ag Optical chemical / biochemical sensor
US5738992A (en) * 1991-06-07 1998-04-14 Chiron Corporation Multiple output referencing system for evanescent wave sensor
WO1999058963A1 (en) * 1998-05-14 1999-11-18 Zeptosens Ag Sensing unit provided with separated detection light guiding
WO2000004188A2 (en) * 1998-07-15 2000-01-27 Chiron Corporation Methods and compositions for comparing and normalizing assays
US6078705A (en) * 1995-05-12 2000-06-20 Novartis Ag Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8803000D0 (en) * 1988-02-10 1988-03-09 Ekins Roger Philip Determination of ambient concentrations of several analytes
US5807755A (en) * 1987-08-06 1998-09-15 Multilyte Limited Determination of ambient concentrations of several analytes
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
CA2087413A1 (en) * 1992-01-17 1993-07-18 Joseph R. Lakowicz Fluorescent energy transfer immunoassay
GB9212302D0 (en) * 1992-06-10 1992-07-22 Applied Research Systems Method for improving measurement precision in evanescent wave optical biosensor assays
GB9326450D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
US5577137A (en) * 1995-02-22 1996-11-19 American Research Corporation Of Virginia Optical chemical sensor and method using same employing a multiplicity of fluorophores contained in the free volume of a polymeric optical waveguide or in pores of a ceramic waveguide
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
US5770370A (en) * 1996-06-14 1998-06-23 David Sarnoff Research Center, Inc. Nuclease protection assays
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
US6082185A (en) * 1997-07-25 2000-07-04 Research International, Inc. Disposable fluidic circuit cards
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6780582B1 (en) * 1998-07-14 2004-08-24 Zyomyx, Inc. Arrays of protein-capture agents and methods of use thereof
WO2000050871A1 (en) * 1999-02-26 2000-08-31 Orchid Biosciences, Inc. Microstructures for use in biological assays and reactions
EP1212599A2 (de) * 1999-08-30 2002-06-12 Illumina, Inc. Verfahren zur verbesserung des signals einer sensorarray
US6649416B1 (en) * 2000-02-18 2003-11-18 Trustees Of Tufts College Intelligent electro-optical sensor array and method for analyte detection
AU2001279135A1 (en) * 2000-07-31 2002-02-13 Maxygen, Inc. Biosensors, reagents and diagnostic applications of directed evolution
EP2189783A1 (de) * 2000-08-09 2010-05-26 Artificial Sensing Instruments ASI AG Wellenleitergitterstruktur und optische Messanordnung
US20040043479A1 (en) * 2000-12-11 2004-03-04 Briscoe Cynthia G. Multilayerd microfluidic devices for analyte reactions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5738992A (en) * 1991-06-07 1998-04-14 Chiron Corporation Multiple output referencing system for evanescent wave sensor
US6078705A (en) * 1995-05-12 2000-06-20 Novartis Ag Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence
EP0789242A2 (de) * 1996-02-06 1997-08-13 Roche Diagnostics GmbH Werkstoffe und Verfahren für Bindungsassays
WO1998008077A1 (de) * 1996-08-16 1998-02-26 Novartis Ag Optische detektionsvorrichtung
WO1998009156A1 (en) * 1996-08-29 1998-03-05 Novartis Ag Optical chemical / biochemical sensor
WO1999058963A1 (en) * 1998-05-14 1999-11-18 Zeptosens Ag Sensing unit provided with separated detection light guiding
WO2000004188A2 (en) * 1998-07-15 2000-01-27 Chiron Corporation Methods and compositions for comparing and normalizing assays

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KUNZ R E: "Miniature integrated optical modules for chemical and biochemical sensing", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 38, no. 1-3, 1997, pages 13 - 28, XP004083666, ISSN: 0925-4005 *
SCHENA M ET AL: "PARALLEL HUMAN GENOME ANALYSIS: MICROARRAY-BASED EXPRESSION MONITORING OF 1000 GENES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 20, 1 October 1996 (1996-10-01), pages 10614 - 10619, XP002022507, ISSN: 0027-8424 *
SCHICK E ET AL: "Ultrasensitive multianalyte immunoassays: The synergy between planar waveguide- and microarray technology", EUROPEAN BIOPHYSICS JOURNAL, SPRINGER, TOKYO, JP, vol. 29, no. 4-5, 22 August 2000 (2000-08-22), pages 379, XP002205023, ISSN: 0175-7571 *
SCORILAS ANDREAS ET AL: "Streptavidin-polyvinylamine conjugates labeled with a Europium chelate: Applications in immunoassay, immunohistochemistry, and microarrays.", CLINICAL CHEMISTRY, vol. 46, no. 9, September 2000 (2000-09-01), Meeting on Capture, Binding, and Detection Technologies in Clinical Diagnostics Immunoassays, Nucleic Acids, and more held at the 32nd Annual Oak Ridge Conference;Boston, Massachusetts, USA; May 05-06, pages 1450 - 1455, XP002228591, ISSN: 0009-9147 *
STEEMERS FRANK J ET AL: "Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 18, no. 1, January 2000 (2000-01-01), pages 91 - 94, XP002202592, ISSN: 1087-0156 *

Also Published As

Publication number Publication date
US20040058385A1 (en) 2004-03-25
WO2002040998A2 (de) 2002-05-23
AU2002224831A1 (en) 2002-05-27
EP1334361A2 (de) 2003-08-13

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