WO2002027017A3 - Method for quantifying phosphokinase activity on proteins - Google Patents
Method for quantifying phosphokinase activity on proteins Download PDFInfo
- Publication number
- WO2002027017A3 WO2002027017A3 PCT/US2001/030186 US0130186W WO0227017A3 WO 2002027017 A3 WO2002027017 A3 WO 2002027017A3 US 0130186 W US0130186 W US 0130186W WO 0227017 A3 WO0227017 A3 WO 0227017A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- phosphorylation
- protein
- proteins
- quantifying
- tau
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01973567A EP1328812B1 (en) | 2000-09-27 | 2001-09-27 | Method for quantifying phosphokinase activity on proteins |
DE60136840T DE60136840D1 (en) | 2000-09-27 | 2001-09-27 | METHOD FOR QUANTITATING PHOSPHOKINASE ACTIVITY ON PROTEINS |
CA2423979A CA2423979C (en) | 2000-09-27 | 2001-09-27 | Method for quantifying phosphokinase activity on proteins |
JP2002530779A JP2004516823A (en) | 2000-09-27 | 2001-09-27 | Method for quantification of phosphokinase activity on proteins |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23562000P | 2000-09-27 | 2000-09-27 | |
US60/235,620 | 2000-09-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002027017A2 WO2002027017A2 (en) | 2002-04-04 |
WO2002027017A3 true WO2002027017A3 (en) | 2003-01-16 |
Family
ID=22886277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/030186 WO2002027017A2 (en) | 2000-09-27 | 2001-09-27 | Method for quantifying phosphokinase activity on proteins |
Country Status (7)
Country | Link |
---|---|
US (4) | US20030162230A1 (en) |
EP (3) | EP2040078A1 (en) |
JP (2) | JP2004516823A (en) |
AT (1) | ATE416385T1 (en) |
CA (1) | CA2423979C (en) |
DE (1) | DE60136840D1 (en) |
WO (1) | WO2002027017A2 (en) |
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US20040014082A1 (en) * | 2000-08-11 | 2004-01-22 | Invitrogen Corporation | Highly homogeneous molecular markers for electrophoresis |
US20030162230A1 (en) * | 2000-09-27 | 2003-08-28 | Reagan Kevin J. | Method for quantifying phosphokinase activity on proteins |
GB0208104D0 (en) * | 2002-04-09 | 2002-05-22 | Univ Dundee | Method |
JP4563171B2 (en) | 2002-05-24 | 2010-10-13 | シェーリング コーポレイション | Neutralizing human anti-IGFR antibody |
US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
EP1668146B1 (en) * | 2003-09-25 | 2014-11-12 | Life Technologies Corporation | Homogeneous populations of molecules |
CN1938428A (en) | 2003-11-12 | 2007-03-28 | 先灵公司 | Plasmid system for multigene expression |
TW200526684A (en) | 2003-11-21 | 2005-08-16 | Schering Corp | Anti-IGFR1 antibody therapeutic combinations |
DE602005025685D1 (en) | 2004-12-03 | 2011-02-10 | Schering Corp | BIOLOGICAL MARKERS FOR THE PRESELECTION OF PATIENTS FOR ANTI-IGF1R THERAPY |
US7807789B2 (en) * | 2004-12-21 | 2010-10-05 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in EGFR-signaling pathways |
WO2007005605A2 (en) * | 2005-07-01 | 2007-01-11 | Washington University In St. Louis | Phosphospecific chemokine receptor antibodies |
WO2007133688A2 (en) * | 2006-05-12 | 2007-11-22 | Cell Signaling Technology, Inc. | Reagents for the detection of tyrosine phosphorylation in brain ischemia signaling pathways |
WO2008147687A1 (en) * | 2007-05-21 | 2008-12-04 | Mayo Foundation For Medical Education And Research | Treating pancreatitis |
KR101612442B1 (en) * | 2008-05-13 | 2016-04-15 | 삼성전자주식회사 | Method and apparatus for providing and using Content Advisory for Internet contents |
WO2011120082A1 (en) * | 2010-03-29 | 2011-10-06 | Medvet Science Pty. Ltd. | A method of modulating protein 14-3-3 functionality by facilitating or inhibiting phosphorylation |
US20130164274A1 (en) * | 2010-09-07 | 2013-06-27 | Stephen G. Marx | Kit for monitoring, detecting and staging gvhd |
US20170016900A1 (en) | 2010-09-07 | 2017-01-19 | Stephen G. Marx | Kit for monitoring, detecting and staging gvhd |
US9200068B2 (en) | 2012-12-18 | 2015-12-01 | Regents Of The University Of Minnesota | Compositions and methods related to tauopathy |
PT3083680T (en) | 2013-12-20 | 2020-03-17 | Hoffmann La Roche | Humanized anti-tau(ps422) antibodies and methods of use |
EP3088898B1 (en) * | 2013-12-27 | 2024-02-07 | National University Corporation Tokyo Medical and Dental University | Method for diagnosis of alzheimer's disease and frontotemporal lobar degeneration, diagnostic agent, therapeutic agent, and screening method for said agents |
CN106062560A (en) * | 2014-03-31 | 2016-10-26 | 默克专利股份公司 | Method for detecting protein modifications using specific antibodies |
AR100978A1 (en) | 2014-06-26 | 2016-11-16 | Hoffmann La Roche | ANTI-Tau HUMANIZED ANTIBODY BRAIN LAUNCHERS (pS422) AND USES OF THE SAME |
US9862763B2 (en) | 2015-06-24 | 2018-01-09 | Hoffmann-La Roche Inc. | Humanized anti-tau(pS422) antibodies and methods of use |
JO3711B1 (en) * | 2015-07-13 | 2021-01-31 | H Lundbeck As | Antibodies specific for hyperphosphorylated tau and methods of use thereof |
MA45655B1 (en) | 2016-07-12 | 2021-04-30 | H Lundbeck As | Hyperphosphorylated tau protein specific antibodies and methods of use thereof |
EP3324187B1 (en) * | 2016-11-21 | 2020-03-11 | Ruhr-Universität Bochum | Combined assay for the differential diagnosis of the alzheimer's disease |
MA47205A (en) | 2017-01-04 | 2019-11-13 | H Lundbeck As | SPECIFIC ANTIBODIES OF HYPERPHOSPHORYLATED TAU PROTEIN TO TREAT EYE DISEASES |
WO2019126141A1 (en) * | 2017-12-18 | 2019-06-27 | Yale University | Compounds and compositions for treating fibrosis |
US10591492B2 (en) | 2018-03-05 | 2020-03-17 | Janssen Pharmaceutica Nv | Assays to detect neurodegeneration |
US11085935B2 (en) | 2018-05-03 | 2021-08-10 | Washington University | Methods of treating based on site-specific tau phosphorylation |
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WO1996004309A1 (en) * | 1994-07-29 | 1996-02-15 | Innogenetics N.V. | Monoclonal antibodies specific for an epitope of a particular subclass or form of phosphorylated tau, hybridomas secreting them, antigen recognition of these antibodies and their applications |
WO1999024473A1 (en) * | 1997-11-07 | 1999-05-20 | Aventis Pharma Deutschland Gmbh | Antibodies against phosphorylated vasp (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use |
WO1999029894A1 (en) * | 1997-12-05 | 1999-06-17 | Pharmacia & Upjohn Company | Fluorescence-based high throughput screening assays for protein kinases and phosphatases |
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US20030162230A1 (en) | 2000-09-27 | 2003-08-28 | Reagan Kevin J. | Method for quantifying phosphokinase activity on proteins |
-
2001
- 2001-09-07 US US09/948,972 patent/US20030162230A1/en not_active Abandoned
- 2001-09-27 AT AT01973567T patent/ATE416385T1/en not_active IP Right Cessation
- 2001-09-27 EP EP08169121A patent/EP2040078A1/en not_active Withdrawn
- 2001-09-27 CA CA2423979A patent/CA2423979C/en not_active Expired - Lifetime
- 2001-09-27 DE DE60136840T patent/DE60136840D1/en not_active Expired - Lifetime
- 2001-09-27 EP EP01973567A patent/EP1328812B1/en not_active Expired - Lifetime
- 2001-09-27 EP EP10179876A patent/EP2298814A3/en not_active Withdrawn
- 2001-09-27 WO PCT/US2001/030186 patent/WO2002027017A2/en active Application Filing
- 2001-09-27 JP JP2002530779A patent/JP2004516823A/en not_active Withdrawn
-
2006
- 2006-03-22 JP JP2006079226A patent/JP2006225396A/en active Pending
-
2008
- 2008-07-24 US US12/179,526 patent/US7888050B2/en not_active Expired - Fee Related
-
2010
- 2010-12-16 US US12/970,250 patent/US8114617B2/en not_active Expired - Fee Related
-
2011
- 2011-09-26 US US13/245,045 patent/US20120135426A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
---|---|
US20090104628A1 (en) | 2009-04-23 |
EP2298814A2 (en) | 2011-03-23 |
EP1328812B1 (en) | 2008-12-03 |
DE60136840D1 (en) | 2009-01-15 |
CA2423979C (en) | 2012-03-06 |
US20030162230A1 (en) | 2003-08-28 |
ATE416385T1 (en) | 2008-12-15 |
US7888050B2 (en) | 2011-02-15 |
EP1328812A2 (en) | 2003-07-23 |
WO2002027017A2 (en) | 2002-04-04 |
CA2423979A1 (en) | 2002-04-04 |
JP2004516823A (en) | 2004-06-10 |
JP2006225396A (en) | 2006-08-31 |
EP2040078A1 (en) | 2009-03-25 |
US8114617B2 (en) | 2012-02-14 |
US20120135426A1 (en) | 2012-05-31 |
US20110165588A1 (en) | 2011-07-07 |
EP2298814A3 (en) | 2012-05-30 |
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