WO2001094666A3 - Spatially addressable electrolysis platform and methods of use - Google Patents

Spatially addressable electrolysis platform and methods of use Download PDF

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Publication number
WO2001094666A3
WO2001094666A3 PCT/CA2001/000832 CA0100832W WO0194666A3 WO 2001094666 A3 WO2001094666 A3 WO 2001094666A3 CA 0100832 W CA0100832 W CA 0100832W WO 0194666 A3 WO0194666 A3 WO 0194666A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
electrode
spatially addressable
platform
electrolysis platform
Prior art date
Application number
PCT/CA2001/000832
Other languages
French (fr)
Other versions
WO2001094666A2 (en
Inventor
Andrei K Yudin
Tung Siu
Wei Li
Original Assignee
Ylektra Inc
Andrei K Yudin
Tung Siu
Wei Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ylektra Inc, Andrei K Yudin, Tung Siu, Wei Li filed Critical Ylektra Inc
Priority to CA002411891A priority Critical patent/CA2411891A1/en
Priority to AU2001267197A priority patent/AU2001267197A1/en
Priority to US10/297,628 priority patent/US20040094407A1/en
Priority to EP01944800A priority patent/EP1292388A2/en
Publication of WO2001094666A2 publication Critical patent/WO2001094666A2/en
Publication of WO2001094666A3 publication Critical patent/WO2001094666A3/en

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00495Means for heating or cooling the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00599Solution-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00709Type of synthesis
    • B01J2219/00713Electrochemical synthesis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00759Purification of compounds synthesised
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Abstract

An electrochemical cell system and method are described. The electrochemical cell system provides a matrix of reaction cells (110) with a first electrode in each cell (110) and a single multiple element counter electrode (120, 130) wherein there is a separate element which is inserted into each cell (110). Methods and applications of the multiple electrode platform are described. Also described are modified electrodes having immobilized redox catalysts at the electrode surfaces and their use in optimizing performance in electrochemical processes.
PCT/CA2001/000832 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use WO2001094666A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002411891A CA2411891A1 (en) 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use
AU2001267197A AU2001267197A1 (en) 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use
US10/297,628 US20040094407A1 (en) 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use
EP01944800A EP1292388A2 (en) 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20999500P 2000-06-08 2000-06-08
US60/209,995 2000-06-08

Publications (2)

Publication Number Publication Date
WO2001094666A2 WO2001094666A2 (en) 2001-12-13
WO2001094666A3 true WO2001094666A3 (en) 2002-07-18

Family

ID=22781186

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/000832 WO2001094666A2 (en) 2000-06-08 2001-06-08 Spatially addressable electrolysis platform and methods of use

Country Status (5)

Country Link
US (1) US20040094407A1 (en)
EP (1) EP1292388A2 (en)
AU (1) AU2001267197A1 (en)
CA (1) CA2411891A1 (en)
WO (1) WO2001094666A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070272294A1 (en) * 2003-09-09 2007-11-29 Yi-Tao Long Photocurrent Generator
CN100404122C (en) * 2003-09-09 2008-07-23 埃德南文斯科技公司 Photocurrent generator
US20060172881A1 (en) * 2004-12-22 2006-08-03 Devaraj Neal K Method of spatially controlling catalysis of a chemical reaction

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR57226E (en) * 1947-07-07 1952-12-23 Process and apparatus for electro-thermochemical operations such as in particular combustions, distillations, synthetic reactions, molecular or atomic dissociations and other similar operations, particularly on organic bodies
WO1997049987A1 (en) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. High-throughput screening method and apparatus
US5929208A (en) * 1993-11-01 1999-07-27 Nanogen, Inc. Methods for electronic synthesis of polymers
WO1999066329A1 (en) * 1998-06-12 1999-12-23 Cenes Limited High throughput screen
WO1999067019A1 (en) * 1998-06-24 1999-12-29 Therasense, Inc. Combinatorial electrochemical syntheses
WO2000007728A2 (en) * 1998-07-31 2000-02-17 Commissariat A L'energie Atomique Micro-system with multiple points for chemical or biological analysis
WO2001043866A1 (en) * 1999-12-13 2001-06-21 Hte Ag Method for producing material libraries by means of electrochemical deposition
WO2001085328A1 (en) * 2000-05-12 2001-11-15 Avantium International B. V. Device and method for electrochemically generating one or more gases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2532476A1 (en) * 1982-09-01 1984-03-02 Commissariat Energie Atomique IMPROVEMENT TO ELECTROCHEMICAL GENERATORS COMPRISING AN ORGANIC POLYMER AS AN ACTIVE ELECTRODE MATERIAL
US5415758A (en) * 1993-11-19 1995-05-16 Theobald Smith Research Institute, Inc. Method and apparatus for electro-elution of biological molecules
US6683446B1 (en) * 1998-12-22 2004-01-27 John Pope Electrode array for development and testing of materials
US6468410B1 (en) * 1999-06-14 2002-10-22 Eveready Battery Company, Inc. Method for synthesis and characterization of electrode materials

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR57226E (en) * 1947-07-07 1952-12-23 Process and apparatus for electro-thermochemical operations such as in particular combustions, distillations, synthetic reactions, molecular or atomic dissociations and other similar operations, particularly on organic bodies
US5929208A (en) * 1993-11-01 1999-07-27 Nanogen, Inc. Methods for electronic synthesis of polymers
WO1997049987A1 (en) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. High-throughput screening method and apparatus
WO1999066329A1 (en) * 1998-06-12 1999-12-23 Cenes Limited High throughput screen
WO1999067019A1 (en) * 1998-06-24 1999-12-29 Therasense, Inc. Combinatorial electrochemical syntheses
WO2000007728A2 (en) * 1998-07-31 2000-02-17 Commissariat A L'energie Atomique Micro-system with multiple points for chemical or biological analysis
WO2001043866A1 (en) * 1999-12-13 2001-06-21 Hte Ag Method for producing material libraries by means of electrochemical deposition
WO2001085328A1 (en) * 2000-05-12 2001-11-15 Avantium International B. V. Device and method for electrochemically generating one or more gases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TUNG SIU ET AL.: "PARALLEL ELECTROSYNTHESIS OF ALPHA-ALKOXYCARBAMATES, ALPHA-ALKOXYAMIDES, AND ALPHA-ALKOXYSULFONAMIDES USING THE SPATIALLY ADDRESSABLE ELECTROLYIS PLATFORM (SAEP)", JOURNAL OF COMBINATORIAL CHEMISTRY, vol. 2, no. 5, 12 September 2000 (2000-09-12), WASHINGTON, DC, US, pages 545 - 549, XP001058994, ISSN: 1520-4766 *

Also Published As

Publication number Publication date
US20040094407A1 (en) 2004-05-20
CA2411891A1 (en) 2001-12-13
EP1292388A2 (en) 2003-03-19
AU2001267197A1 (en) 2001-12-17
WO2001094666A2 (en) 2001-12-13

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