WO2001080825A3 - Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof - Google Patents

Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof Download PDF

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Publication number
WO2001080825A3
WO2001080825A3 PCT/US2001/012700 US0112700W WO0180825A3 WO 2001080825 A3 WO2001080825 A3 WO 2001080825A3 US 0112700 W US0112700 W US 0112700W WO 0180825 A3 WO0180825 A3 WO 0180825A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
drug delivery
sustained release
release drug
manufacturing
Prior art date
Application number
PCT/US2001/012700
Other languages
French (fr)
Other versions
WO2001080825A2 (en
Inventor
Hong Guo
Paul Ashton
Original Assignee
Control Delivery Sys Inc
Hong Guo
Paul Ashton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2001253675A priority Critical patent/AU2001253675B2/en
Priority to CA2406277A priority patent/CA2406277C/en
Application filed by Control Delivery Sys Inc, Hong Guo, Paul Ashton filed Critical Control Delivery Sys Inc
Priority to IL15229401A priority patent/IL152294A0/en
Priority to EA200201140A priority patent/EA004980B1/en
Priority to NZ522002A priority patent/NZ522002A/en
Priority to EP01927200A priority patent/EP1276462B1/en
Priority to AU5367501A priority patent/AU5367501A/en
Priority to DK01927200T priority patent/DK1276462T3/en
Priority to BR0110243-5A priority patent/BR0110243A/en
Priority to MXPA02010442A priority patent/MXPA02010442A/en
Priority to JP2001577925A priority patent/JP4705304B2/en
Priority to DE60135907T priority patent/DE60135907D1/en
Priority to KR1020027014204A priority patent/KR100854541B1/en
Priority to SI200130887T priority patent/SI1276462T1/en
Publication of WO2001080825A2 publication Critical patent/WO2001080825A2/en
Publication of WO2001080825A3 publication Critical patent/WO2001080825A3/en
Priority to IL152294A priority patent/IL152294A/en
Priority to HK03105207.5A priority patent/HK1053263B/en
Priority to AU2006202338A priority patent/AU2006202338B2/en
Priority to AU2008261114A priority patent/AU2008261114B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y10T29/49888—Subsequently coating

Abstract

A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube.
PCT/US2001/012700 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof WO2001080825A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
JP2001577925A JP4705304B2 (en) 2000-04-26 2001-04-19 Sustained release drug delivery system, method of use, and method of manufacture
MXPA02010442A MXPA02010442A (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
DE60135907T DE60135907D1 (en) 2000-04-26 2001-04-19 AGGRAVATED ADMINISTRATION SYSTEMS WITH DELAYED RELEASE, USE AND METHOD OF MANUFACTURING THE SAME
CA2406277A CA2406277C (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
NZ522002A NZ522002A (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices
EP01927200A EP1276462B1 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU5367501A AU5367501A (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
DK01927200T DK1276462T3 (en) 2000-04-26 2001-04-19 Delivery Device Release Devices, Methods of Use and Methods of Preparing
BR0110243-5A BR0110243A (en) 2000-04-26 2001-04-19 A sustained release drug delivery system, and methods for treating a mammalian organism, to provide sustained and controlled administration of an effective agent to achieve a desired local or systemic physiological or pharmacological effect, and to manufacture a system prolonged drug application
AU2001253675A AU2001253675B2 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
EA200201140A EA004980B1 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use and methods of manufacturing thereof
IL15229401A IL152294A0 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
KR1020027014204A KR100854541B1 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
SI200130887T SI1276462T1 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
IL152294A IL152294A (en) 2000-04-26 2002-10-15 Sustained release drug delivery system and method of manufacturing it
HK03105207.5A HK1053263B (en) 2000-04-26 2003-07-18 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU2006202338A AU2006202338B2 (en) 2000-04-26 2006-06-01 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU2008261114A AU2008261114B2 (en) 2000-04-26 2008-12-18 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/558,207 2000-04-26
US09/558,207 US6375972B1 (en) 2000-04-26 2000-04-26 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof

Publications (2)

Publication Number Publication Date
WO2001080825A2 WO2001080825A2 (en) 2001-11-01
WO2001080825A3 true WO2001080825A3 (en) 2002-06-20

Family

ID=24228594

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012700 WO2001080825A2 (en) 2000-04-26 2001-04-19 Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof

Country Status (24)

Country Link
US (7) US6375972B1 (en)
EP (2) EP1982701A3 (en)
JP (1) JP4705304B2 (en)
KR (1) KR100854541B1 (en)
CN (4) CN1438873A (en)
AR (1) AR028372A1 (en)
AT (1) ATE409023T1 (en)
AU (4) AU2001253675B2 (en)
BR (1) BR0110243A (en)
CA (1) CA2406277C (en)
CY (1) CY1108665T1 (en)
DE (1) DE60135907D1 (en)
DK (1) DK1276462T3 (en)
EA (1) EA004980B1 (en)
ES (1) ES2315282T3 (en)
HK (1) HK1053263B (en)
IL (2) IL152294A0 (en)
MX (1) MXPA02010442A (en)
NZ (2) NZ531721A (en)
PT (1) PT1276462E (en)
SI (1) SI1276462T1 (en)
TW (1) TWI290054B (en)
WO (1) WO2001080825A2 (en)
ZA (1) ZA200208415B (en)

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US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices

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