WO2001064095A3 - Multidimensional bioelectrical tissue analyzer - Google Patents

Multidimensional bioelectrical tissue analyzer Download PDF

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Publication number
WO2001064095A3
WO2001064095A3 PCT/US2001/006657 US0106657W WO0164095A3 WO 2001064095 A3 WO2001064095 A3 WO 2001064095A3 US 0106657 W US0106657 W US 0106657W WO 0164095 A3 WO0164095 A3 WO 0164095A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
impedance measurements
multidimensional
pathologies
tissue
Prior art date
Application number
PCT/US2001/006657
Other languages
French (fr)
Other versions
WO2001064095A2 (en
Inventor
Peter Littrup
Robert Duncan
Original Assignee
Karmanos B A Cancer Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karmanos B A Cancer Inst filed Critical Karmanos B A Cancer Inst
Priority to AU2001250790A priority Critical patent/AU2001250790A1/en
Publication of WO2001064095A2 publication Critical patent/WO2001064095A2/en
Publication of WO2001064095A3 publication Critical patent/WO2001064095A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6804—Garments; Clothes
    • A61B5/6806—Gloves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp

Abstract

A method and apparatus that use complex impedance measurements of tissue in human or animal bodies for the detection and characterization of medical pathologies is disclosed. An analysis of the complex impedance measurements is performed by a trained evaluation system that uses a nonlinear continuum model to analyze the resistive, capacitive, and inductive measurements collected from a plurality of sensing electrodes. The analysis of the impedance measurements results in the construction of a multidimensional space that defines the tissue characteristics, which the trained evaluation system uses to detect and characterize pathologies. The method and apparatus are sufficiently general to be applied to various types of human and animal tissues for the analysis of various types of medical pathologies.
PCT/US2001/006657 2000-02-28 2001-02-28 Multidimensional bioelectrical tissue analyzer WO2001064095A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001250790A AU2001250790A1 (en) 2000-02-28 2001-02-28 Multidimensional bioelectrical tissue analyzer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18541300P 2000-02-28 2000-02-28
US60/185,413 2000-02-28
US09/794,612 2001-02-27
US09/794,612 US7499745B2 (en) 2000-02-28 2001-02-27 Multidimensional bioelectrical tissue analyzer

Publications (2)

Publication Number Publication Date
WO2001064095A2 WO2001064095A2 (en) 2001-09-07
WO2001064095A3 true WO2001064095A3 (en) 2002-03-07

Family

ID=26881117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/006657 WO2001064095A2 (en) 2000-02-28 2001-02-28 Multidimensional bioelectrical tissue analyzer

Country Status (3)

Country Link
US (1) US7499745B2 (en)
AU (1) AU2001250790A1 (en)
WO (1) WO2001064095A2 (en)

Families Citing this family (216)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6385474B1 (en) * 1999-03-19 2002-05-07 Barbara Ann Karmanos Cancer Institute Method and apparatus for high-resolution detection and characterization of medical pathologies
AUPQ113799A0 (en) * 1999-06-22 1999-07-15 University Of Queensland, The A method and device for measuring lymphoedema
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US6460413B1 (en) * 2001-03-15 2002-10-08 Gerald J. Diebold Imaging based on the electroacoustic effect
US7409243B2 (en) * 2001-04-04 2008-08-05 Mirabel Medical Ltd. Breast cancer detection
US20060161073A1 (en) * 2001-05-03 2006-07-20 Singer Michael G In vitro and in vivo assessment of organs and tissue and use, transplant, freshness and tissue conditions
US7003346B2 (en) * 2001-05-03 2006-02-21 Singer Michaeal G Method for illness and disease determination and management
IL143374A0 (en) * 2001-05-24 2002-04-21 Transscan Medical Ltd Anomaly detection based on signal variations
US7044911B2 (en) * 2001-06-29 2006-05-16 Philometron, Inc. Gateway platform for biological monitoring and delivery of therapeutic compounds
US7505811B2 (en) 2001-11-19 2009-03-17 Dune Medical Devices Ltd. Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus
US7809425B2 (en) 2003-07-24 2010-10-05 Dune Medical Devices Ltd. Method and apparatus for examining a substance, particularly tissue, to characterize its type
US8019411B2 (en) 2002-01-04 2011-09-13 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US8721565B2 (en) 2005-08-04 2014-05-13 Dune Medical Devices Ltd. Device for forming an effective sensor-to-tissue contact
US8032211B2 (en) 2002-01-04 2011-10-04 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US8116845B2 (en) 2005-08-04 2012-02-14 Dune Medical Devices Ltd. Tissue-characterization probe with effective sensor-to-tissue contact
US7720532B2 (en) 2004-03-23 2010-05-18 Dune Medical Ltd. Clean margin assessment tool
US20080154090A1 (en) * 2005-01-04 2008-06-26 Dune Medical Devices Ltd. Endoscopic System for In-Vivo Procedures
US6980852B2 (en) * 2002-01-25 2005-12-27 Subqiview Inc. Film barrier dressing for intravascular tissue monitoring system
AU2003219491A1 (en) 2002-04-04 2003-10-20 Transscan Medical Ltd. Impedance measurements on breast nipples
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US8262575B2 (en) 2002-05-20 2012-09-11 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue
US20040152997A1 (en) * 2002-05-20 2004-08-05 Davies Richard J. Electrophysiological approaches to assess resection and tumor ablation margins and responses to drug therapy
US6922586B2 (en) * 2002-05-20 2005-07-26 Richard J. Davies Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue
US7630759B2 (en) 2002-05-20 2009-12-08 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium
DE10238824A1 (en) * 2002-08-23 2004-03-11 Forschungszentrum Jülich GmbH Method and device for the rapid tomographic measurement of the electrical conductivity distribution in a sample
AU2002951925A0 (en) * 2002-10-09 2002-10-24 Queensland University Of Technology An Impedence Cardiography Device
US8594764B2 (en) * 2003-03-07 2013-11-26 Jon Rice Device and method for assessing the electrical potential of cells and method for manufacture of same
CN100473336C (en) * 2003-07-24 2009-04-01 沙丘医疗设备有限公司 Method and apparatus for examining a substance, particularly tissue, to characterize type
EP2382920A1 (en) * 2003-08-20 2011-11-02 Philometron, Inc. Hydration monitoring
AU2004285412A1 (en) 2003-09-12 2005-05-12 Minnow Medical, Llc Selectable eccentric remodeling and/or ablation of atherosclerotic material
PL1725168T3 (en) 2004-03-06 2016-10-31 Body fluid sampling device
US7819822B2 (en) * 2004-03-06 2010-10-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
US9750425B2 (en) 2004-03-23 2017-09-05 Dune Medical Devices Ltd. Graphical user interfaces (GUI), methods and apparatus for data presentation
US7904145B2 (en) 2004-03-23 2011-03-08 Dune Medical Devices Ltd. Clean margin assessment tool
US7474918B2 (en) * 2004-03-24 2009-01-06 Noninvasive Medical Technologies, Inc. Thoracic impedance monitor and electrode array and method of use
US7970461B2 (en) * 2004-06-18 2011-06-28 Andres Kink Method and apparatus for determining conditions of a biological tissue
WO2005122888A1 (en) 2004-06-18 2005-12-29 The University Of Queensland Oedema detection
US8068906B2 (en) 2004-06-21 2011-11-29 Aorora Technologies Pty Ltd Cardiac monitoring system
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US7742795B2 (en) * 2005-03-28 2010-06-22 Minnow Medical, Inc. Tuned RF energy for selective treatment of atheroma and other target tissues and/or structures
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
EP1824539A1 (en) * 2004-12-08 2007-08-29 Novo Nordisk A/S Apparatus and method for assisting in choosing a site for a skin invasive action
EP1890596B1 (en) 2005-03-29 2013-10-02 Dune Medical Devices Ltd. Electromagnetic sensors for tissue characterization
JP2008536650A (en) * 2005-04-21 2008-09-11 エピ‐サイ，リミテッド・ライアビリティ・カンパニー Methods and systems for detecting electrophysiological changes in pre-cancerous and cancerous tissues and epithelial tissues
US20080009764A1 (en) * 2005-04-21 2008-01-10 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium
JP5607300B2 (en) 2005-07-01 2014-10-15 インぺディメッド リミテッド Apparatus and method for performing impedance measurements on an object
EP2250963A3 (en) 2005-07-01 2012-02-29 Intersection Medical, Inc. Pulmonary monitoring system
AU2006265763B2 (en) 2005-07-01 2012-08-09 Impedimed Limited Monitoring system
CA2615845A1 (en) * 2005-07-20 2007-01-25 Impedance Cardiology Systems, Inc. Index determination
GB0516158D0 (en) * 2005-08-05 2005-09-14 Univ Montfort An apparatus and method for `non-contact' electrical impedance imaging
CA2625631C (en) 2005-10-11 2016-11-29 Impedance Cardiology Systems, Inc. Hydration status monitoring
US9492226B2 (en) 2005-12-06 2016-11-15 St. Jude Medical, Atrial Fibrillation Division, Inc. Graphical user interface for real-time RF lesion depth display
US9254163B2 (en) 2005-12-06 2016-02-09 St. Jude Medical, Atrial Fibrillation Division, Inc. Assessment of electrode coupling for tissue ablation
US8406866B2 (en) 2005-12-06 2013-03-26 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for assessing coupling between an electrode and tissue
AU2006321918B2 (en) 2005-12-06 2011-08-25 St. Jude Medical, Atrial Fibrillation Division Inc. Assessment of electrode coupling for tissue ablation
EP1956972A2 (en) * 2005-12-06 2008-08-20 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium
US8403925B2 (en) 2006-12-06 2013-03-26 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for assessing lesions in tissue
US10362959B2 (en) 2005-12-06 2019-07-30 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for assessing the proximity of an electrode to tissue in a body
US8998890B2 (en) 2005-12-06 2015-04-07 St. Jude Medical, Atrial Fibrillation Division, Inc. Assessment of electrode coupling for tissue ablation
US8603084B2 (en) 2005-12-06 2013-12-10 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for assessing the formation of a lesion in tissue
US7794404B1 (en) 2006-03-31 2010-09-14 Pacesetter, Inc System and method for estimating cardiac pressure using parameters derived from impedance signals detected by an implantable medical device
US8712519B1 (en) 2006-03-31 2014-04-29 Pacesetter, Inc. Closed-loop adaptive adjustment of pacing therapy based on cardiogenic impedance signals detected by an implantable medical device
US8600497B1 (en) 2006-03-31 2013-12-03 Pacesetter, Inc. Systems and methods to monitor and treat heart failure conditions
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US20080039746A1 (en) 2006-05-25 2008-02-14 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
ES2545730T3 (en) 2006-05-30 2015-09-15 Impedimed Limited Impedance measurements
US8929979B2 (en) 2006-06-19 2015-01-06 Highland Instruments, Inc. Apparatus and method for stimulation of biological tissue
US9623241B2 (en) 2006-06-19 2017-04-18 Highland Instruments Treatment methods
US9913976B2 (en) 2006-06-19 2018-03-13 Highland Instruments, Inc. Systems and methods for stimulating and monitoring biological tissue
JP5479901B2 (en) 2006-10-18 2014-04-23 べシックス・バスキュラー・インコーポレイテッド Induction of desired temperature effects on body tissue
EP2455034B1 (en) 2006-10-18 2017-07-19 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
CA2666661C (en) 2006-10-18 2015-01-20 Minnow Medical, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
WO2008064426A1 (en) 2006-11-30 2008-06-05 Impedimed Limited Measurement apparatus
US8147423B2 (en) * 2007-03-01 2012-04-03 Dune Medical Devices, Ltd. Tissue-characterization system and method
US8504152B2 (en) 2007-04-04 2013-08-06 Pacesetter, Inc. System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device
US8208999B2 (en) 2007-04-04 2012-06-26 Pacesetter, Inc. System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device
US10307074B2 (en) * 2007-04-20 2019-06-04 Impedimed Limited Monitoring system and probe
US8496653B2 (en) 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
US10201324B2 (en) 2007-05-04 2019-02-12 Delphinus Medical Technologies, Inc. Patient interface system
WO2009018620A1 (en) 2007-08-09 2009-02-12 Impedimed Limited Impedance measurement process
JP2011505966A (en) * 2007-12-11 2011-03-03 エピ‐サイ，リミテッド・ライアビリティ・カンパニー Electrical bioimpedance analysis as a biomarker of breast density and / or breast cancer risk
US9204927B2 (en) 2009-05-13 2015-12-08 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for presenting information representative of lesion formation in tissue during an ablation procedure
US8290578B2 (en) * 2007-12-28 2012-10-16 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and apparatus for complex impedance compensation
US20110264000A1 (en) * 2007-12-28 2011-10-27 Saurav Paul System and method for determining tissue type and mapping tissue morphology
WO2009083992A1 (en) * 2008-01-03 2009-07-09 Soreq Nuclear Research Center Bone fracture detection
EP2273920B1 (en) 2008-01-22 2017-12-13 Yeda Research and Development Co. Ltd. Method and device for monitoring breastfeeding
AU2008207672B2 (en) 2008-02-15 2013-10-31 Impedimed Limited Impedance Analysis
CA2758827A1 (en) * 2008-04-21 2009-10-29 Philometron, Inc. Metabolic energy monitoring system
US8386010B2 (en) * 2008-10-23 2013-02-26 Covidien Lp Surgical tissue monitoring system
CN102271603A (en) 2008-11-17 2011-12-07 明诺医学股份有限公司 Selective accumulation of energy with or without knowledge of tissue topography
AU2009321478B2 (en) 2008-11-28 2014-01-23 Impedimed Limited Impedance measurement process
US20100191141A1 (en) * 2009-01-27 2010-07-29 Peter Aberg Method and apparatus for diagnosing a diseased condition in tissue of a subject
KR20110108387A (en) 2009-01-27 2011-10-05 싸이베이스 에이비 Switch probe for multiple electrode measurement of impedance
US9050016B2 (en) * 2009-02-10 2015-06-09 Siemens Medical Solutions Usa, Inc. System for heart performance characterization and abnormality detection
WO2010120823A2 (en) * 2009-04-13 2010-10-21 Research Foundation Of The City University Of New York Neurocranial electrostimulation models, systems, devices and methods
US8551096B2 (en) 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
WO2011007569A1 (en) * 2009-07-15 2011-01-20 国立大学法人筑波大学 Classification estimating system and classification estimating program
US8825131B2 (en) 2009-10-14 2014-09-02 Nocimed, Llc MR spectroscopy system and method for diagnosing painful and non-painful intervertebral discs
US8761860B2 (en) 2009-10-14 2014-06-24 Nocimed, Llc MR spectroscopy system and method for diagnosing painful and non-painful intervertebral discs
JP5643829B2 (en) 2009-10-26 2014-12-17 インぺディメッド リミテッドＩｍｐｅｄｉｍｅｄ Ｌｉｍｉｔｅｄ Method and apparatus for use in impedance measurement analysis
TW201116256A (en) * 2009-11-09 2011-05-16 Charder Electronic Co Ltd Device for measuring human body composition by using biolectrical impedance method and artificial neural network
EP2501283B1 (en) 2009-11-18 2016-09-21 Impedimed Limited Signal distribution for patient-electrode measurements
US9075910B2 (en) * 2010-03-11 2015-07-07 Philometron, Inc. Physiological monitor system for determining medication delivery and outcome
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US20140148726A1 (en) * 2010-10-21 2014-05-29 Timothy Andrew WAGNER Methods for detecting a condition
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9280718B2 (en) 2010-11-24 2016-03-08 Nocimed, Llc Systems and methods for automated voxelation of regions of interest for magnetic resonance spectroscopy
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
AU2012283908B2 (en) 2011-07-20 2017-02-16 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
WO2013016203A1 (en) 2011-07-22 2013-01-31 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
AU2012326218B2 (en) 2011-10-17 2017-03-09 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
EP2775948B1 (en) 2011-11-08 2018-04-04 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
EP2779929A1 (en) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
WO2013090798A1 (en) 2011-12-14 2013-06-20 Intersection Medical, Inc. Devices, systems and methods for determining the relative spatial change in subsurface resistivities across frequencies in tissue
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096913A2 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10456060B2 (en) * 2012-02-22 2019-10-29 Ghassan S. Kassab Devices for detecting organ contents using impedance and methods of using the same to provide various therapies
US8965094B2 (en) 2012-04-14 2015-02-24 Nocimed, Llc Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
RU2503409C1 (en) * 2012-07-11 2014-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Северо-Западный государственный медицинский университет им. И.И. Мечникова" Министерства здравоохранения и социального развития Российской Федерации Method of determining progression of cancer of abdominal cavity organs
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US9763641B2 (en) 2012-08-30 2017-09-19 Delphinus Medical Technologies, Inc. Method and system for imaging a volume of tissue with tissue boundary detection
EP2895095A2 (en) 2012-09-17 2015-07-22 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
JP6074051B2 (en) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Intravascular neuromodulation system and medical device
CN102908125B (en) * 2012-10-30 2014-08-13 中国人民解放军第四军医大学 Vivid physical simulation model for electrical impedance scanning imaging of breast
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US10123770B2 (en) 2013-03-13 2018-11-13 Delphinus Medical Technologies, Inc. Patient support system
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
AU2014233354B2 (en) 2013-03-15 2017-01-12 Medtronic Af Luxembourg S.A.R.L. Controlled neuromodulation systems and methods of use
JP6220044B2 (en) 2013-03-15 2017-10-25 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Medical device for renal nerve ablation
CN105228546B (en) 2013-03-15 2017-11-14 波士顿科学国际有限公司 Utilize the impedance-compensated medicine equipment and method that are used to treat hypertension
US9667889B2 (en) 2013-04-03 2017-05-30 Butterfly Network, Inc. Portable electronic devices with integrated imaging capabilities
JP2016523125A (en) 2013-05-30 2016-08-08 グラハム エイチ． クリーシー Local nervous stimulation
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Medical device for renal nerve ablation having a rotatable shaft
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
WO2015002787A1 (en) 2013-07-01 2015-01-08 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
EP3049007B1 (en) 2013-07-19 2019-06-12 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
JP6159888B2 (en) 2013-08-22 2017-07-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Flexible circuit with improved adhesion to renal neuromodulation balloon
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
CN105530885B (en) 2013-09-13 2020-09-22 波士顿科学国际有限公司 Ablation balloon with vapor deposited covering
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
WO2015057521A1 (en) 2013-10-14 2015-04-23 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
EP3057520A1 (en) 2013-10-15 2016-08-24 Boston Scientific Scimed, Inc. Medical device balloon
JP6259099B2 (en) 2013-10-18 2018-01-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Balloon catheter comprising a conductive wire with flexibility, and related uses and manufacturing methods
CN105658163B (en) 2013-10-25 2020-08-18 波士顿科学国际有限公司 Embedded thermocouple in denervation flexible circuit
WO2015103617A1 (en) 2014-01-06 2015-07-09 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
KR101987408B1 (en) * 2014-01-21 2019-06-11 삼성전자주식회사 Apparatus and method of measuring bio impedence
EP3102136B1 (en) 2014-02-04 2018-06-27 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US10143443B2 (en) 2014-05-05 2018-12-04 Delphinus Medical Technologies, Inc. Method for representing tissue stiffness
US10743837B2 (en) 2014-08-04 2020-08-18 Delphinus Medical Technologies, Inc. Ultrasound waveform tomography method and system
US10285667B2 (en) 2014-08-05 2019-05-14 Delphinus Medical Technologies, Inc. Method for generating an enhanced image of a volume of tissue
ES2562810B1 (en) * 2014-08-06 2016-12-27 Universidad De Sevilla Bioimpedance measurement system for real-time and wireless monitoring of cell cultures based on an oscillation test using integrated circuits
USD759803S1 (en) 2014-10-28 2016-06-21 Highland Instruments, Inc. Adjustable headpiece with anatomical markers
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US9872628B2 (en) 2015-07-03 2018-01-23 Elwha Llc Electrocardiogram systems and related methods
US10258252B1 (en) * 2015-09-24 2019-04-16 David Cudney Wound measurement and tracking system and method
CN108463174B (en) * 2015-12-18 2021-06-08 皇家飞利浦有限公司 Device and method for characterizing tissue of a subject
WO2017222945A1 (en) 2016-06-19 2017-12-28 Nocimed, Inc. Magnetic resonance spectroscopy system and method for diagnosing pain or infection associated with propionic acid
WO2018091746A1 (en) * 2016-11-21 2018-05-24 Sensome Characterizing and identifying biological structure
WO2018132898A1 (en) 2017-01-17 2018-07-26 Uti Limited Partnership Positioning device for medical devices
CN110381813B (en) * 2017-03-02 2022-10-21 圣犹达医疗用品心脏病学部门有限公司 System and method for distinguishing adipose tissue and scar tissue during electrophysiology mapping
US10952654B2 (en) 2017-03-14 2021-03-23 International Business Machines Corporation PH sensitive surgical tool
US10229092B2 (en) 2017-08-14 2019-03-12 City University Of Hong Kong Systems and methods for robust low-rank matrix approximation
WO2019060298A1 (en) 2017-09-19 2019-03-28 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
JP2021510608A (en) 2017-11-07 2021-04-30 ニューロスティム オーエービー インコーポレイテッド Non-invasive nerve activator with adaptive circuit
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
WO2019133997A1 (en) 2017-12-31 2019-07-04 Neuroenhancement Lab, LLC System and method for neuroenhancement to enhance emotional response
US11253189B2 (en) 2018-01-24 2022-02-22 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and methods for evaluating neuromodulation therapy via detection of magnetic fields
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
WO2019223874A1 (en) * 2018-05-24 2019-11-28 Scibase Ab Impedance measurement device
US11300558B2 (en) * 2018-06-14 2022-04-12 Nokomis, Inc. Apparatus and system for spectroscopy and tomography of fragile biologic materials
EP3849410A4 (en) 2018-09-14 2022-11-02 Neuroenhancement Lab, LLC System and method of improving sleep
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
JP2022538419A (en) 2019-06-26 2022-09-02 ニューロスティム テクノロジーズ エルエルシー Noninvasive neuroactivation device with adaptive circuitry
EP4017580A4 (en) 2019-12-16 2023-09-06 Neurostim Technologies LLC Non-invasive nerve activator with boosted charge delivery
EP4090236A4 (en) * 2020-01-17 2024-02-14 Prolung Inc Dba Ioniq Sciences Noninvasive medical diagnostics using electrical impedance metrics and clinical predictors
US11197634B2 (en) 2020-04-28 2021-12-14 Wayne C. A. Wright Geospatial bioimpedance biosurveillance tool
US11596802B2 (en) 2020-08-12 2023-03-07 Starlight Investments, Llc Biofield apparatus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407300A (en) * 1980-07-14 1983-10-04 Davis Robert E Potentiometric diagnosis of cancer in vivo
US5143079A (en) * 1989-08-02 1992-09-01 Yeda Research And Development Company Limited Apparatus for detection of tumors in tissue
US6201990B1 (en) * 1997-10-02 2001-03-13 Tasc Ltd. Electrical impedance tomography method

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870578A (en) 1987-08-19 1989-09-26 Bomed Medical Manufacturing, Ltd. Diastolic clamp for bioimpedance measuring device
US4920490A (en) 1988-01-28 1990-04-24 Rensselaer Polytechnic Institute Process and apparatus for distinguishing conductivities by electric current computed tomography
US4955383A (en) 1988-12-22 1990-09-11 Biofield Corporation Discriminant function analysis method and apparatus for disease diagnosis and screening
US5427098A (en) 1988-12-22 1995-06-27 Biofield Corp. Noninvasive method for determining treatment based upon lesion cell proliferation measurements
US5697369A (en) 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
US5099844A (en) 1988-12-22 1992-03-31 Biofield Corp. Discriminant function analysis method and apparatus for disease diagnosis and screening
US5678547A (en) 1988-12-22 1997-10-21 Biofield Corp. Method and apparatus for screening or sensing bodily conditions using DC biopotentials
US5588429A (en) 1991-07-09 1996-12-31 Rensselaer Polytechnic Institute Process for producing optimal current patterns for electrical impedance tomography
US5544662A (en) * 1991-07-09 1996-08-13 Rensselaer Polytechnic Institute High-speed electric tomography
US5390110A (en) 1991-07-09 1995-02-14 Rensselaer Polytechnic Institute Layer stripping process for impedance imaging
US5381333A (en) 1991-07-23 1995-01-10 Rensselaer Polytechnic Institute Current patterns for electrical impedance tomography
GB9116215D0 (en) 1991-07-26 1991-09-11 Nat Res Dev Electrical impedance tomography
US5260871A (en) * 1991-07-31 1993-11-09 Mayo Foundation For Medical Education And Research Method and apparatus for diagnosis of breast tumors
US5187096A (en) 1991-08-08 1993-02-16 Rensselaer Polytechnic Institute Cell substrate electrical impedance sensor with multiple electrode array
US5217014A (en) 1991-11-04 1993-06-08 Biofield Corp. Depolarized pre-gelled electrodes
US5415164A (en) 1991-11-04 1995-05-16 Biofield Corp. Apparatus and method for screening and diagnosing trauma or disease in body tissues
US5660177A (en) 1991-11-04 1997-08-26 Biofield Corp. D.C. biopotential sensing electrode assemblies for apparatus for disease, injury and bodily condition screening or sensing
US5351697A (en) 1991-12-16 1994-10-04 Rensseleaer Polytechnic Institute Three-dimensional impedance imaging process
GB9200065D0 (en) 1992-01-03 1992-02-26 Nycomed As Contrast media
GB9222888D0 (en) 1992-10-30 1992-12-16 British Tech Group Tomography
GB9226376D0 (en) 1992-12-18 1993-02-10 British Tech Group Tomography
JP3759606B2 (en) 1994-03-11 2006-03-29 ビーティージー・インターナショナル・リミテッド Electrical impedance tomography
US5823957A (en) 1994-10-17 1998-10-20 Biofield Corp D.C. biopotential sensing electrode and electroconductive medium for use therein
US5810742A (en) * 1994-10-24 1998-09-22 Transcan Research & Development Co., Ltd. Tissue characterization based on impedance images and on impedance measurements
US5919142A (en) 1995-06-22 1999-07-06 Btg International Limited Electrical impedance tomography method and apparatus
US6408443B1 (en) * 2001-04-18 2002-06-25 Dada Corp. Reversible visor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407300A (en) * 1980-07-14 1983-10-04 Davis Robert E Potentiometric diagnosis of cancer in vivo
US5143079A (en) * 1989-08-02 1992-09-01 Yeda Research And Development Company Limited Apparatus for detection of tumors in tissue
US6201990B1 (en) * 1997-10-02 2001-03-13 Tasc Ltd. Electrical impedance tomography method

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