WO2001062962A3 - Component for interaction analysis comprising probe molecule species which create co-operation effects - Google Patents

Component for interaction analysis comprising probe molecule species which create co-operation effects Download PDF

Info

Publication number
WO2001062962A3
WO2001062962A3 PCT/DE2001/000807 DE0100807W WO0162962A3 WO 2001062962 A3 WO2001062962 A3 WO 2001062962A3 DE 0100807 W DE0100807 W DE 0100807W WO 0162962 A3 WO0162962 A3 WO 0162962A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe molecule
component
probe
species
create
Prior art date
Application number
PCT/DE2001/000807
Other languages
German (de)
French (fr)
Other versions
WO2001062962A2 (en
Inventor
Derya Oezkan
Original Assignee
Variom Biotechnology Ag
Derya Oezkan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10053473A external-priority patent/DE10053473A1/en
Application filed by Variom Biotechnology Ag, Derya Oezkan filed Critical Variom Biotechnology Ag
Priority to EP01929220A priority Critical patent/EP1305605A2/en
Priority to AU2001256101A priority patent/AU2001256101A1/en
Publication of WO2001062962A2 publication Critical patent/WO2001062962A2/en
Publication of WO2001062962A3 publication Critical patent/WO2001062962A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02—Optical fibres with cladding with or without a coating
    • G02B6/02033—Core or cladding made from organic material, e.g. polymeric material
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/04—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres
    • G02B6/06—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres the relative position of the fibres being the same at both ends, e.g. for transporting images

Abstract

The invention relates to a component comprising a support and probe molecule fields that are arranged thereon in a defined configuration. Each probe molecule field carries probe molecules of at least one probe molecule species and an association exists between the geometric positions of the probe molecule fields within the component and the species of the probe molecule fields. The invention is characterized in that each probe molecule field carries probe molecules of a respectively different, selected species group, whereby group elements of each species group bind mutually to a defined target molecule by creating co-operative effects.
PCT/DE2001/000807 2000-02-28 2001-02-27 Component for interaction analysis comprising probe molecule species which create co-operation effects WO2001062962A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01929220A EP1305605A2 (en) 2000-02-28 2001-02-27 Component for interaction analysis comprising probe molecule species which create co-operation effects
AU2001256101A AU2001256101A1 (en) 2000-02-28 2001-02-27 Component for interaction analysis comprising probe molecule species which create co-operation effects

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10010376 2000-02-28
DE10010376.6 2000-02-28
DE10053473A DE10053473A1 (en) 2000-02-28 2000-10-20 Component for interaction analysis with sample molecule species that form cooperation effects
DE10053473.2 2000-10-20

Publications (2)

Publication Number Publication Date
WO2001062962A2 WO2001062962A2 (en) 2001-08-30
WO2001062962A3 true WO2001062962A3 (en) 2002-08-29

Family

ID=26004663

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/000807 WO2001062962A2 (en) 2000-02-28 2001-02-27 Component for interaction analysis comprising probe molecule species which create co-operation effects

Country Status (3)

Country Link
EP (1) EP1305605A2 (en)
AU (1) AU2001256101A1 (en)
WO (1) WO2001062962A2 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
DE4128846A1 (en) * 1991-08-30 1993-03-04 Rainer Klein Integrated optical material sensor - comprises light waveguide, coated with immobilised layer, light sources and coupling unit
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
WO1995026416A1 (en) * 1994-03-25 1995-10-05 Research Corporation Technologies, Inc. Nucleic acid biosensor diagnostics
US5525466A (en) * 1991-06-07 1996-06-11 Ciba Corning Diagnostics Corp. Multiple output referencing system for evanescent wave sensor
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
EP0867506A1 (en) * 1996-09-13 1998-09-30 Laboratory of Molecular Biophotonics Solid phase for target nucleic acid detection, process for production thereof, and method of target nucleic acid detection
US5837196A (en) * 1996-01-26 1998-11-17 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5525466A (en) * 1991-06-07 1996-06-11 Ciba Corning Diagnostics Corp. Multiple output referencing system for evanescent wave sensor
DE4128846A1 (en) * 1991-08-30 1993-03-04 Rainer Klein Integrated optical material sensor - comprises light waveguide, coated with immobilised layer, light sources and coupling unit
WO1995026416A1 (en) * 1994-03-25 1995-10-05 Research Corporation Technologies, Inc. Nucleic acid biosensor diagnostics
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5837196A (en) * 1996-01-26 1998-11-17 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
EP0867506A1 (en) * 1996-09-13 1998-09-30 Laboratory of Molecular Biophotonics Solid phase for target nucleic acid detection, process for production thereof, and method of target nucleic acid detection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FERGUSON J A ET AL: "A FIBER-OPTIC DNA BIOSENSOR MICROARRAY FOR THE ANALYSIS OF GENE EXPRESSION", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 14, December 1996 (1996-12-01), pages 1681 - 1684, XP002928887, ISSN: 0733-222X *

Also Published As

Publication number Publication date
EP1305605A2 (en) 2003-05-02
AU2001256101A1 (en) 2001-09-03
WO2001062962A2 (en) 2001-08-30

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