WO2001056633A3 - Single-use therapeutic substance delivery device with infusion rate control - Google Patents

Single-use therapeutic substance delivery device with infusion rate control Download PDF

Info

Publication number
WO2001056633A3
WO2001056633A3 PCT/US2001/003467 US0103467W WO0156633A3 WO 2001056633 A3 WO2001056633 A3 WO 2001056633A3 US 0103467 W US0103467 W US 0103467W WO 0156633 A3 WO0156633 A3 WO 0156633A3
Authority
WO
WIPO (PCT)
Prior art keywords
reservoir
therapeutic substance
delivery device
infusion rate
rate
Prior art date
Application number
PCT/US2001/003467
Other languages
French (fr)
Other versions
WO2001056633A2 (en
Inventor
David L Thompson
Michael F Mattes
Lary R Larson
Kenneth T Heruth
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Publication of WO2001056633A2 publication Critical patent/WO2001056633A2/en
Publication of WO2001056633A3 publication Critical patent/WO2001056633A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3507—Communication with implanted devices, e.g. external control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
    • A61M5/16881—Regulating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The single-use device has a Micro Electro Mechanical system (MEMS) flow restriction (34) with a variable infusion rate. The MEMS flow restriction is fluidly coupled to a reservoir outlet (36) to receive therapeutic substance (26) dispensed from the single-use reservoir (32) at the reservoir rate and restrict the therapeutic substance flow to a desired infusion rate. The single-use reservoir is configured for controlled collapse to dispense therapeutic substance from the reservoir at a reservoir rate through a reservoir outlet. The therapeutic substance delivery device can also be configured as a shrink polymer delivery device. A flow restriction is fluidly coupled to the shrink polymer reservoir outlet to receive therapeutic substance dispensed from the reservoir at the reservoir rate and restrict the therapeutic substance flow to an infusion rate.
PCT/US2001/003467 2000-02-03 2001-02-02 Single-use therapeutic substance delivery device with infusion rate control WO2001056633A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17992400P 2000-02-03 2000-02-03
US60/179,924 2000-02-03

Publications (2)

Publication Number Publication Date
WO2001056633A2 WO2001056633A2 (en) 2001-08-09
WO2001056633A3 true WO2001056633A3 (en) 2002-02-14

Family

ID=22658539

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2001/003536 WO2001056634A1 (en) 2000-02-03 2001-02-02 Variable infusion rate catheter
PCT/US2001/003467 WO2001056633A2 (en) 2000-02-03 2001-02-02 Single-use therapeutic substance delivery device with infusion rate control

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2001/003536 WO2001056634A1 (en) 2000-02-03 2001-02-02 Variable infusion rate catheter

Country Status (2)

Country Link
DE (1) DE10195354T1 (en)
WO (2) WO2001056634A1 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287156T3 (en) * 2000-09-08 2007-12-16 Insulet Corporation DEVICES AND SYSTEMS FOR THE INFUSION OF A PATIENT.
WO2003037305A1 (en) * 2001-09-19 2003-05-08 Durect Corporation Flow regulator
US20030130625A1 (en) * 2002-01-07 2003-07-10 Jacobson James D. Infusion system
EP1398049A1 (en) * 2002-09-09 2004-03-17 Novo Nordisk A/S Flow restrictor
DE60309487T2 (en) * 2002-09-09 2007-09-20 Novo Nordisk A/S FLOW RESTRICTOR WITH SAFETY FEATURES
US7186247B2 (en) 2003-04-04 2007-03-06 Medtronic, Inc. Apparatus and system for delivery of drug therapies
US7367968B2 (en) 2003-09-05 2008-05-06 Codman & Shurtleff, Inc. Implantable pump with adjustable flow rate
US8165695B2 (en) 2004-02-11 2012-04-24 Ethicon, Inc. System and method for selectively stimulating different body parts
US7647112B2 (en) 2004-02-11 2010-01-12 Ethicon, Inc. System and method for selectively stimulating different body parts
US7979137B2 (en) 2004-02-11 2011-07-12 Ethicon, Inc. System and method for nerve stimulation
US8751003B2 (en) 2004-02-11 2014-06-10 Ethicon, Inc. Conductive mesh for neurostimulation
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
US8100889B2 (en) 2004-11-10 2012-01-24 Olympus Corporation Body-insertable apparatus
US20060122565A1 (en) * 2004-11-23 2006-06-08 Kooi Chee C Switch structures or the like based on a thermoresponsive polymer
AT501555B1 (en) * 2005-02-25 2006-12-15 Hoerbiger Automatisierungstech VALVE ASSEMBLY, ARRANGEMENT OF AIR-FILLABLE BUBBLE AND VEHICLE SEAT, PROVIDED WITH SEVERAL BUBBLES
EP1998829B1 (en) * 2006-03-14 2011-02-09 University Of Southern California Mems device for delivery of therapeutic agents
EP2666510B1 (en) 2007-12-20 2017-10-18 University Of Southern California Apparatus for controlled delivery of therapeutic agents
US20090192493A1 (en) 2008-01-03 2009-07-30 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
US8231609B2 (en) 2008-05-08 2012-07-31 Minipumps, Llc Drug-delivery pumps and methods of manufacture
CN103394142B (en) 2008-05-08 2015-08-19 迷你泵有限责任公司 Implantable drug delivery devices with for filling equipment and the method for this device
CN104353150A (en) 2008-05-08 2015-02-18 迷你泵有限责任公司 Implantable pums and cannulas therefor
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
KR101696175B1 (en) 2008-06-11 2017-01-23 브라코 다이어그노스틱스 아이엔씨. Cabinet structure configurations for infusion systems
US8317674B2 (en) 2008-06-11 2012-11-27 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
EP2467797B1 (en) 2009-08-18 2017-07-19 MiniPumps, LLC Electrolytic drug-delivery pump with adaptive control
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
EP3549524B1 (en) 2012-03-30 2023-01-25 Insulet Corporation Fluid delivery device with transcutaneous access tool, insertion mechanism and blood glucose monitoring for use therewith
DE102013212325A1 (en) 2013-06-26 2014-12-31 B. Braun Melsungen Ag Adjustment device for a flow regulator
EP3380061A4 (en) 2015-11-24 2019-07-24 Insulet Corporation Wearable automated medication delivery system
WO2017091584A1 (en) 2015-11-25 2017-06-01 Insulet Corporation Wearable medication delivery device
CN109964285B (en) 2016-09-20 2024-01-09 布拉科诊断公司 Systems and techniques for generating, infusing, and controlling radioisotope delivery
CN106492326B (en) * 2016-11-27 2019-09-06 中国人民解放军第四军医大学 A kind of method of variable cavity sealing multi-cavity medical catheter and opening
US11045603B2 (en) 2017-02-22 2021-06-29 Insulet Corporation Needle insertion mechanisms for drug containers
US10898656B2 (en) 2017-09-26 2021-01-26 Insulet Corporation Needle mechanism module for drug delivery device
US11147931B2 (en) 2017-11-17 2021-10-19 Insulet Corporation Drug delivery device with air and backflow elimination
CN112106148A (en) 2018-03-28 2020-12-18 布拉科诊断公司 Early detection of radioisotope generator lifetime
KR20240014931A (en) * 2022-07-26 2024-02-02 재단법인대구경북과학기술원 Drug delivery apparatus and system

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447224A (en) * 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4772263A (en) * 1986-02-03 1988-09-20 Regents Of The University Of Minnesota Spring driven infusion pump
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5702618A (en) * 1993-10-04 1997-12-30 Research International, Inc. Methods for manufacturing a flow switch
WO1998023869A1 (en) * 1996-11-25 1998-06-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Piezo-electrically actuated microvalve
US5820589A (en) * 1996-04-30 1998-10-13 Medtronic, Inc. Implantable non-invasive rate-adjustable pump
EP0892419A2 (en) * 1997-07-18 1999-01-20 TRW Inc. Micro electro-mechanical system (MEMS) switch
US5897530A (en) * 1997-12-24 1999-04-27 Baxter International Inc. Enclosed ambulatory pump
EP0951916A2 (en) * 1998-04-23 1999-10-27 Medtronic, Inc. Implantable drug infusion device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254091A (en) * 1984-09-28 1989-05-16 Vladimir Feingold Implantable medication infusion system
NL8701644A (en) * 1987-07-13 1989-02-01 Cordis Europ DEVICE FOR DOSING IN THE BODY OF A LIQUID MATERIAL.
US4931050A (en) * 1988-04-13 1990-06-05 Shiley Infusaid Inc. Constant pressure variable flow pump
US5252962A (en) 1990-08-03 1993-10-12 Bio Medic Data Systems System monitoring programmable implantable transponder
JPH05220222A (en) * 1992-02-17 1993-08-31 Olympus Optical Co Ltd Flow control device
FR2689403A1 (en) * 1992-04-01 1993-10-08 Celsa Lg Device for injecting a drug via an implantable chamber and tool facilitating its use.
US5833603A (en) 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447224A (en) * 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4772263A (en) * 1986-02-03 1988-09-20 Regents Of The University Of Minnesota Spring driven infusion pump
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5702618A (en) * 1993-10-04 1997-12-30 Research International, Inc. Methods for manufacturing a flow switch
US5820589A (en) * 1996-04-30 1998-10-13 Medtronic, Inc. Implantable non-invasive rate-adjustable pump
WO1998023869A1 (en) * 1996-11-25 1998-06-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Piezo-electrically actuated microvalve
EP0892419A2 (en) * 1997-07-18 1999-01-20 TRW Inc. Micro electro-mechanical system (MEMS) switch
US5897530A (en) * 1997-12-24 1999-04-27 Baxter International Inc. Enclosed ambulatory pump
EP0951916A2 (en) * 1998-04-23 1999-10-27 Medtronic, Inc. Implantable drug infusion device

Also Published As

Publication number Publication date
WO2001056634A1 (en) 2001-08-09
DE10195354T1 (en) 2003-05-08
WO2001056633A2 (en) 2001-08-09

Similar Documents

Publication Publication Date Title
WO2001056633A3 (en) Single-use therapeutic substance delivery device with infusion rate control
EP1512422B1 (en) Implantable pump with adjustable flow rate
WO2003024504A3 (en) Plunger for patient infusion device
WO2007095297A3 (en) Fluid dispensing apparatus with flow rate control
EP3020431B1 (en) Regulator for drug infusion and drug infusion device including same
AU2001261297A1 (en) Micro infusion drug delivery device
KR970706857A (en) INFUSION PUMP WITH TUBE SPIKE HOLDER WITH TUBE SPIKE HOLDER
WO2005118053A3 (en) Fluid delivery device
CA2224244A1 (en) Patient controlled drug delivery device
ATE408430T1 (en) MEDICINAL INFUSION SYSTEM
NZ268414A (en) Liquid dispenser including a vent mechanism to vent gas from a pressure control chamber to drive a reciprocatable pumping member through a stroke to draw liquid
ATE420681T1 (en) MODULAR DEVICE FOR ADMINISTRATION OF MEDICATION
CA2379187A1 (en) Ostomy irrigation system
WO2008030462A3 (en) Disposable infusion device with automatic unlocking mechanism
WO2002020073A3 (en) Devices, systems and methods for patient infusion
WO2005118052A3 (en) Infusion apparatus
TW200510023A (en) Infusion system
MX9801372A (en) Multi-dose syringe driver.
CA2369068A1 (en) Monolithic high performance miniature flow control unit
WO2009125398A3 (en) Modular skin-adherable system for medical fluid delivery
CA2616128A1 (en) Miniature pump for drug delivery
WO2005037350A3 (en) Internal fluid connector for establishing a fluid connection
WO2008030461A3 (en) Disposable infusion device with air trapping collapsible reservoir
ATE216219T1 (en) MICROCHIP DRUG DELIVERY SYSTEMS
WO2002028454A3 (en) Data collection assembly for patient infusion system

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): DE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): DE

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642