WO2001043721A3 - Dosage forms having a barrier layer to laser ablation - Google Patents

Dosage forms having a barrier layer to laser ablation Download PDF

Info

Publication number
WO2001043721A3
WO2001043721A3 PCT/US2000/033494 US0033494W WO0143721A3 WO 2001043721 A3 WO2001043721 A3 WO 2001043721A3 US 0033494 W US0033494 W US 0033494W WO 0143721 A3 WO0143721 A3 WO 0143721A3
Authority
WO
WIPO (PCT)
Prior art keywords
barrier layer
wall
laser ablation
dosage form
exit orifice
Prior art date
Application number
PCT/US2000/033494
Other languages
French (fr)
Other versions
WO2001043721A2 (en
Inventor
Johan H Geerke
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT00990203T priority Critical patent/ATE290365T1/en
Priority to HU0203860A priority patent/HUP0203860A3/en
Priority to AU27263/01A priority patent/AU780045B2/en
Priority to IL15023900A priority patent/IL150239A0/en
Application filed by Alza Corp filed Critical Alza Corp
Priority to DK00990203T priority patent/DK1239830T3/en
Priority to EP00990203A priority patent/EP1239830B1/en
Priority to DE60018606T priority patent/DE60018606T2/en
Priority to JP2001544660A priority patent/JP2003516809A/en
Priority to NZ519632A priority patent/NZ519632A/en
Priority to CA002394968A priority patent/CA2394968A1/en
Priority to MXPA02006031A priority patent/MXPA02006031A/en
Publication of WO2001043721A2 publication Critical patent/WO2001043721A2/en
Publication of WO2001043721A3 publication Critical patent/WO2001043721A3/en
Priority to NO20022840A priority patent/NO20022840L/en
Priority to HK03108652A priority patent/HK1056320A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Abstract

A dosage form for delivery of a therapeutic agent to a subject is described. The dosage form contains: (a) an outer wall defining an interior compartment; (b) within the interior compartment, a therapeutic agent; (c) at least one exit orifice formed by laser ablation of the outer wall for release of the agent therethrough, and (d) a barrier layer disposed between the outer wall and the interior compartment in at least a region corresponding to the exit orifice. The barrier layer comprises a material that allows the barrier layer to remain intact during laser-formation of the at least one exit orifice in the outer wall. Also disclosed is a method for controlling the depth of laser ablation of a dosage form during laser formation of an exit orifice in an outer wall of the dosage form.
PCT/US2000/033494 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation WO2001043721A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
EP00990203A EP1239830B1 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation
AU27263/01A AU780045B2 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation
IL15023900A IL150239A0 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation
JP2001544660A JP2003516809A (en) 1999-12-16 2000-12-11 Dosage form with barrier layer for laser ablation
DK00990203T DK1239830T3 (en) 1999-12-16 2000-12-11 Dosage forms with barrier layer for laser removal
HU0203860A HUP0203860A3 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation
DE60018606T DE60018606T2 (en) 1999-12-16 2000-12-11 Dosage forms with a barrier layer against laser ablation
AT00990203T ATE290365T1 (en) 1999-12-16 2000-12-11 DOSAGE FORMS WITH A BARRIER LAYER AGAINST LASER ABLATION
NZ519632A NZ519632A (en) 1999-12-16 2000-12-11 Dosage forms that include a barrier layer containing a material that allows the layer to remain intact during laser formation of the orifice(s)
CA002394968A CA2394968A1 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation
MXPA02006031A MXPA02006031A (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation.
NO20022840A NO20022840L (en) 1999-12-16 2002-06-14 Dosage form with a barrier layer for laser removal
HK03108652A HK1056320A1 (en) 1999-12-16 2003-11-27 Dosage forms having a barrier layer to laser ablation.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17237199P 1999-12-16 1999-12-16
US60/172,371 1999-12-16

Publications (2)

Publication Number Publication Date
WO2001043721A2 WO2001043721A2 (en) 2001-06-21
WO2001043721A3 true WO2001043721A3 (en) 2002-01-03

Family

ID=22627445

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/033494 WO2001043721A2 (en) 1999-12-16 2000-12-11 Dosage forms having a barrier layer to laser ablation

Country Status (21)

Country Link
US (2) US7011850B2 (en)
EP (1) EP1239830B1 (en)
JP (1) JP2003516809A (en)
KR (1) KR100810956B1 (en)
CN (1) CN1198584C (en)
AR (1) AR027905A1 (en)
AT (1) ATE290365T1 (en)
AU (1) AU780045B2 (en)
CA (1) CA2394968A1 (en)
DE (1) DE60018606T2 (en)
ES (1) ES2239065T3 (en)
HK (1) HK1056320A1 (en)
HU (1) HUP0203860A3 (en)
IL (1) IL150239A0 (en)
MX (1) MXPA02006031A (en)
NO (1) NO20022840L (en)
NZ (1) NZ519632A (en)
PT (1) PT1239830E (en)
TW (1) TWI270378B (en)
WO (1) WO2001043721A2 (en)
ZA (1) ZA200204766B (en)

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Publication number Priority date Publication date Assignee Title
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
KR200249057Y1 (en) * 2001-03-22 2001-10-19 김진환 Sewage backflow integrated into the lid and base. Odor Prevention Device
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
US8637080B2 (en) * 2007-06-28 2014-01-28 Osmotica Kereskedelmi és Szolgáltató, KFT Rupturing controlled release device comprising a subcoat
EP3785683B1 (en) * 2009-05-18 2023-11-01 Dose Medical Corporation Drug eluting ocular implant
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
WO2011118454A1 (en) 2010-03-23 2011-09-29 リンテック株式会社 Solid preparation
DE102011078651A1 (en) * 2011-07-05 2013-01-10 Robert Bosch Gmbh Method for producing at least one through-hole and apparatus for carrying out such a method
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
CN109937025B (en) 2016-04-20 2022-07-29 多斯医学公司 Delivery device for bioabsorbable ocular drugs
KR20200013170A (en) * 2018-07-20 2020-02-06 주식회사 코아팜바이오 A tablet with controlled drug release structure and a method of manufacturing the same using 3D printing technology

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
GB2174299A (en) * 1985-04-22 1986-11-05 Alza Corp Osmotic dispenser
US5049722A (en) * 1989-09-16 1991-09-17 Rolls-Royce Plc Laser barrier material and method of laser drilling
US5140127A (en) * 1989-09-20 1992-08-18 Rolls-Royce Plc Laser barrier material
US5767482A (en) * 1995-07-14 1998-06-16 Rolls Royce Plc Laser barrier material and method

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
US2799241A (en) 1949-01-21 1957-07-16 Wisconsin Alumni Res Found Means for applying coatings to tablets or the like
US3854770A (en) 1972-11-20 1974-12-17 Pioneer Coveralls Inc Truck cover
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4519801A (en) 1982-07-12 1985-05-28 Alza Corporation Osmotic device with wall comprising cellulose ether and permeability enhancer
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US5082668A (en) 1983-05-11 1992-01-21 Alza Corporation Controlled-release system with constant pushing source
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
FI89313C (en) * 1985-09-13 1995-12-04 Planmeca Oy Styrsystem Foer panoramatomografiroentgenanordning
US4892778A (en) 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
US4915954A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering a drug at two different rates
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5783793A (en) 1996-02-29 1998-07-21 Merck & Co., Inc. Process for producing a plurality of holes in dosage forms using a laser beam deflected by an acousto-optic deflector
EP1126827A2 (en) 1998-11-02 2001-08-29 Alza Corporation Controlled delivery of active agents
JP2003501375A (en) 1999-06-04 2003-01-14 アルザ・コーポレーション Implantable gel composition and method of manufacture

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
GB2174299A (en) * 1985-04-22 1986-11-05 Alza Corp Osmotic dispenser
US5049722A (en) * 1989-09-16 1991-09-17 Rolls-Royce Plc Laser barrier material and method of laser drilling
US5140127A (en) * 1989-09-20 1992-08-18 Rolls-Royce Plc Laser barrier material
US5767482A (en) * 1995-07-14 1998-06-16 Rolls Royce Plc Laser barrier material and method

Also Published As

Publication number Publication date
IL150239A0 (en) 2002-12-01
CA2394968A1 (en) 2001-06-21
ZA200204766B (en) 2003-06-13
ATE290365T1 (en) 2005-03-15
EP1239830A2 (en) 2002-09-18
AU2726301A (en) 2001-06-25
MXPA02006031A (en) 2003-01-28
KR20020067551A (en) 2002-08-22
HK1056320A1 (en) 2004-02-13
HUP0203860A2 (en) 2003-05-28
US20020071866A1 (en) 2002-06-13
PT1239830E (en) 2005-05-31
JP2003516809A (en) 2003-05-20
DE60018606D1 (en) 2005-04-14
US7011850B2 (en) 2006-03-14
DE60018606T2 (en) 2005-07-28
WO2001043721A2 (en) 2001-06-21
ES2239065T3 (en) 2005-09-16
CN1198584C (en) 2005-04-27
AR027905A1 (en) 2003-04-16
TWI270378B (en) 2007-01-11
CN1424906A (en) 2003-06-18
US20050220879A1 (en) 2005-10-06
EP1239830B1 (en) 2005-03-09
KR100810956B1 (en) 2008-03-10
NO20022840L (en) 2002-08-13
NZ519632A (en) 2004-03-26
AU780045B2 (en) 2005-02-24
NO20022840D0 (en) 2002-06-14
HUP0203860A3 (en) 2004-06-28

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