WO2001038565A3 - Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche - Google Patents
Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche Download PDFInfo
- Publication number
- WO2001038565A3 WO2001038565A3 PCT/DE2000/004301 DE0004301W WO0138565A3 WO 2001038565 A3 WO2001038565 A3 WO 2001038565A3 DE 0004301 W DE0004301 W DE 0004301W WO 0138565 A3 WO0138565 A3 WO 0138565A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oligomers
- general formula
- pna
- dna oligomers
- oligomer array
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Abstract
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA02005221A MXPA02005221A (es) | 1999-11-25 | 2000-11-24 | Arreglo de oligomeros con oligomeros de adn y/o adn sobre una superficie. |
AU28270/01A AU784238B2 (en) | 1999-11-25 | 2000-11-24 | Oligomer array with PNA and/or DNA oligomers on a surface |
IL14980100A IL149801A0 (en) | 1999-11-25 | 2000-11-24 | Oligomer array with pna and/or dna oligomers on a surface |
NZ51854800A NZ518548A (en) | 1999-11-25 | 2000-11-24 | Oligomer array with PNA and/or DNA oligomers on a surface |
CN008161941A CN1413263B (zh) | 1999-11-25 | 2000-11-24 | 表面上带有pna和/或dna寡聚物的寡聚物阵列 |
DK00993178T DK1232287T3 (da) | 1999-11-25 | 2000-11-24 | Oligomer array med PNA og/eller DNA-oligomerer på en overflade |
CA2390312A CA2390312C (en) | 1999-11-25 | 2000-11-24 | Oligomer array with pna and/or dna oligomers on a surface |
EP00993178A EP1232287B1 (de) | 1999-11-25 | 2000-11-24 | Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche |
US10/148,140 US6936419B1 (en) | 1999-11-25 | 2000-11-24 | Oligomer array with PNA and/or DNA oligomers on a surface |
JP2001539907A JP2003514570A (ja) | 1999-11-25 | 2000-11-24 | 表面上においてpna−および/またはdna−オリゴマーを用いたオリゴマー配列 |
SI200030961T SI1232287T1 (sl) | 1999-11-25 | 2000-11-24 | Oligomerna mreža s PNA- in/ali DNA-oligomeri na površini |
DE50014333T DE50014333D1 (de) | 1999-11-25 | 2000-11-24 | Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche |
IS6364A IS2445B (is) | 1999-11-25 | 2002-04-26 | Fáliðu fylki með PNA og/eða DNA fáliður á yfirborði. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19957827A DE19957827C2 (de) | 1999-11-25 | 1999-11-25 | Verwendung eines Oligomer-Arrays mit PNA- und/oder DNA-Oligomeren auf einer Oberfläche |
DE19957827.3 | 1999-11-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001038565A2 WO2001038565A2 (de) | 2001-05-31 |
WO2001038565A3 true WO2001038565A3 (de) | 2001-11-15 |
Family
ID=7930999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2000/004301 WO2001038565A2 (de) | 1999-11-25 | 2000-11-24 | Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche |
Country Status (16)
Country | Link |
---|---|
US (1) | US6936419B1 (de) |
EP (2) | EP1232287B1 (de) |
JP (2) | JP2003514570A (de) |
CN (1) | CN1413263B (de) |
AT (1) | ATE362548T1 (de) |
AU (1) | AU784238B2 (de) |
CA (1) | CA2390312C (de) |
DE (2) | DE19957827C2 (de) |
DK (1) | DK1232287T3 (de) |
ES (1) | ES2287049T3 (de) |
IL (1) | IL149801A0 (de) |
IS (1) | IS2445B (de) |
MX (1) | MXPA02005221A (de) |
NZ (1) | NZ518548A (de) |
PT (1) | PT1232287E (de) |
WO (1) | WO2001038565A2 (de) |
Families Citing this family (43)
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AU2001247414A1 (en) | 2000-03-14 | 2001-09-24 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
AUPR142500A0 (en) * | 2000-11-13 | 2000-12-07 | Human Genetic Signatures Pty Ltd | A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences |
DE10142643A1 (de) * | 2001-08-31 | 2003-04-24 | Clondiag Chip Tech Gmbh | Detektion von Wechselwirkungen auf Sonden-Arrays |
DE10145226A1 (de) * | 2001-09-13 | 2003-04-10 | Lifebits Ag | Herstellung von trägergebundenen Molekülen |
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US7238518B2 (en) * | 2002-10-04 | 2007-07-03 | Nisshinbo Industries, Inc. | Oligonucleotide-immobilized substrate for detecting methylation |
DE602004028478D1 (de) | 2003-06-17 | 2010-09-16 | Human Genetic Signatures Pty | Verfahren zur genomamplifikation |
EP1668148B1 (de) | 2003-09-04 | 2008-12-31 | Human Genetic Signatures PTY Ltd. | Nukleinsäurenachweistest |
US20050196792A1 (en) * | 2004-02-13 | 2005-09-08 | Affymetrix, Inc. | Analysis of methylation status using nucleic acid arrays |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
DK1794173T3 (da) | 2004-09-10 | 2010-10-25 | Human Genetic Signatures Pty | Amplifikationsblokker indeholdende interkalaterende nukleinsyrer (INA) indeholdende interkalaterende pseudonukleotider (IPN) |
EP1794319B1 (de) | 2004-09-30 | 2014-08-13 | Epigenomics AG | Verfahren zur bereitstellung von dna-fragmenten aus einer archivierten probe |
CN101111606B (zh) | 2004-12-03 | 2012-05-16 | 人类遗传标记控股有限公司 | 通过化学修饰胞嘧啶而简化微生物核酸的方法 |
EP1693468A1 (de) | 2005-02-16 | 2006-08-23 | Epigenomics AG | Verfahren zur Bestimmung des Methylierungsmusters einer Polynukleinsäure |
EP1871912B1 (de) | 2005-04-15 | 2012-02-29 | Epigenomics AG | Verfahren zur Bestimmung der DNA-Methylierung in Blut- oder Urinproben |
CN101203618B (zh) | 2005-05-26 | 2013-03-13 | 人类遗传标记控股有限公司 | 使用含有非常规碱基的引物的等温链置换扩增 |
US8343738B2 (en) | 2005-09-14 | 2013-01-01 | Human Genetic Signatures Pty. Ltd. | Assay for screening for potential cervical cancer |
KR101211747B1 (ko) | 2005-09-22 | 2012-12-12 | 이데미쓰 고산 가부시키가이샤 | 산화물 재료 및 스퍼터링 타겟 |
EP1969139A1 (de) | 2005-11-17 | 2008-09-17 | Epigenomics AG | Verfahren zur bestimmung des dna-methylierungsniveaus einer cpg-position in identischen zellen in einer gewebeprobe |
US7901882B2 (en) | 2006-03-31 | 2011-03-08 | Affymetrix, Inc. | Analysis of methylation using nucleic acid arrays |
JP5244103B2 (ja) | 2006-08-09 | 2013-07-24 | ホームステッド クリニカル コーポレイション | 器官特異的蛋白質およびその使用方法 |
EP2479289B1 (de) | 2007-06-08 | 2016-04-06 | Epigenomics AG | Verfahren zur Methylierungsanalyse |
US8685675B2 (en) | 2007-11-27 | 2014-04-01 | Human Genetic Signatures Pty. Ltd. | Enzymes for amplification and copying bisulphite modified nucleic acids |
ES2742251T3 (es) | 2009-03-16 | 2020-02-13 | Pangu Biopharma Ltd | Composiciones y procedimientos que comprenden variantes de splicing de histidil-tarn sintetasa que tienen actividades biológicas no canónicas |
CA2757289A1 (en) | 2009-03-31 | 2010-10-21 | Atyr Pharma, Inc. | Compositions and methods comprising aspartyl-trna synthetases having non-canonical biological activities |
WO2011139714A2 (en) | 2010-04-26 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
CN103096911B (zh) | 2010-04-27 | 2018-05-29 | Atyr 医药公司 | 与异亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
WO2011139853A2 (en) | 2010-04-28 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases |
WO2011150279A2 (en) | 2010-05-27 | 2011-12-01 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases |
CN103097523B (zh) | 2010-04-29 | 2016-09-28 | Atyr医药公司 | 与天冬酰胺酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
AU2011248457B2 (en) | 2010-04-29 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases |
US8981045B2 (en) | 2010-05-03 | 2015-03-17 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-tRNA synthetases |
US8961961B2 (en) | 2010-05-03 | 2015-02-24 | a Tyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases |
CN105820252B (zh) | 2010-05-03 | 2020-07-21 | Atyr 医药公司 | 与苯丙氨酰-α-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
CA2798139C (en) | 2010-05-04 | 2019-09-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex |
CN103200953B (zh) | 2010-05-14 | 2017-02-15 | Atyr 医药公司 | 与苯丙氨酰‑β‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
AU2011256366C1 (en) | 2010-05-17 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
EP2575857B1 (de) | 2010-06-01 | 2018-01-24 | aTyr Pharma, Inc. | Innovative erkennung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen in zusammenhang mit proteinfragmenten von lysyl-trna-synthetasen |
AU2011289831C1 (en) | 2010-07-12 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
CN103108650A (zh) | 2010-08-25 | 2013-05-15 | Atyr医药公司 | 与酪氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
MY167564A (en) | 2011-09-07 | 2018-09-14 | Human Genetic Signatures Pty Ltd | Molecular detection assay |
EP3311847A1 (de) | 2012-02-16 | 2018-04-25 | Atyr Pharma, Inc. | Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen |
MX367366B (es) | 2012-11-27 | 2019-08-16 | Univ Pontificia Catolica Chile | Composiciones y metodos para diagnosticar tumores de tiroides. |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1993025563A1 (en) * | 1992-06-17 | 1993-12-23 | City Of Hope | A method of detecting and discriminating between nucleic acid sequences |
WO1997046705A1 (en) * | 1996-06-03 | 1997-12-11 | The Johns Hopkins University School Of Medicine | Methylation specific detection |
WO1999028498A2 (de) * | 1997-11-27 | 1999-06-10 | Epigenomics Gmbh | Verfahren zur herstellung komplexer dna-methylierungs-fingerabdrücke |
WO2001027317A2 (de) * | 1999-10-15 | 2001-04-19 | Epigenomics Ag | Verfahren zur unterscheidung von 5-position methylierungsänderungen |
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-
1999
- 1999-11-25 DE DE19957827A patent/DE19957827C2/de not_active Expired - Fee Related
-
2000
- 2000-11-24 DK DK00993178T patent/DK1232287T3/da active
- 2000-11-24 CN CN008161941A patent/CN1413263B/zh not_active Expired - Fee Related
- 2000-11-24 NZ NZ51854800A patent/NZ518548A/xx not_active IP Right Cessation
- 2000-11-24 JP JP2001539907A patent/JP2003514570A/ja active Pending
- 2000-11-24 DE DE50014333T patent/DE50014333D1/de not_active Expired - Lifetime
- 2000-11-24 MX MXPA02005221A patent/MXPA02005221A/es unknown
- 2000-11-24 AU AU28270/01A patent/AU784238B2/en not_active Ceased
- 2000-11-24 EP EP00993178A patent/EP1232287B1/de not_active Expired - Lifetime
- 2000-11-24 IL IL14980100A patent/IL149801A0/xx unknown
- 2000-11-24 CA CA2390312A patent/CA2390312C/en not_active Expired - Fee Related
- 2000-11-24 AT AT00993178T patent/ATE362548T1/de active
- 2000-11-24 WO PCT/DE2000/004301 patent/WO2001038565A2/de active IP Right Grant
- 2000-11-24 PT PT00993178T patent/PT1232287E/pt unknown
- 2000-11-24 EP EP07090045A patent/EP1816216A3/de not_active Withdrawn
- 2000-11-24 ES ES00993178T patent/ES2287049T3/es not_active Expired - Lifetime
- 2000-11-24 US US10/148,140 patent/US6936419B1/en not_active Expired - Fee Related
-
2002
- 2002-04-26 IS IS6364A patent/IS2445B/is unknown
-
2006
- 2006-12-26 JP JP2006350139A patent/JP2007175051A/ja active Pending
Patent Citations (4)
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WO1993025563A1 (en) * | 1992-06-17 | 1993-12-23 | City Of Hope | A method of detecting and discriminating between nucleic acid sequences |
WO1997046705A1 (en) * | 1996-06-03 | 1997-12-11 | The Johns Hopkins University School Of Medicine | Methylation specific detection |
WO1999028498A2 (de) * | 1997-11-27 | 1999-06-10 | Epigenomics Gmbh | Verfahren zur herstellung komplexer dna-methylierungs-fingerabdrücke |
WO2001027317A2 (de) * | 1999-10-15 | 2001-04-19 | Epigenomics Ag | Verfahren zur unterscheidung von 5-position methylierungsänderungen |
Also Published As
Publication number | Publication date |
---|---|
CN1413263B (zh) | 2012-07-04 |
CA2390312A1 (en) | 2001-05-31 |
AU2827001A (en) | 2001-06-04 |
IL149801A0 (en) | 2002-11-10 |
DE19957827A1 (de) | 2001-06-21 |
ES2287049T3 (es) | 2007-12-16 |
IS2445B (is) | 2008-11-15 |
EP1816216A2 (de) | 2007-08-08 |
ATE362548T1 (de) | 2007-06-15 |
PT1232287E (pt) | 2007-08-21 |
DK1232287T3 (da) | 2007-09-24 |
EP1232287B1 (de) | 2007-05-16 |
NZ518548A (en) | 2004-12-24 |
WO2001038565A2 (de) | 2001-05-31 |
DE50014333D1 (de) | 2007-06-28 |
JP2003514570A (ja) | 2003-04-22 |
EP1232287A2 (de) | 2002-08-21 |
DE19957827C2 (de) | 2003-06-12 |
IS6364A (is) | 2002-04-26 |
AU784238B2 (en) | 2006-02-23 |
EP1816216A3 (de) | 2009-06-03 |
CN1413263A (zh) | 2003-04-23 |
JP2007175051A (ja) | 2007-07-12 |
CA2390312C (en) | 2011-05-31 |
US6936419B1 (en) | 2005-08-30 |
MXPA02005221A (es) | 2004-08-23 |
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