WO2001036933A8 - Dispensing apparatus having means for loading pipette tips in a dispense head - Google Patents

Dispensing apparatus having means for loading pipette tips in a dispense head

Info

Publication number
WO2001036933A8
WO2001036933A8 PCT/US2000/031116 US0031116W WO0136933A8 WO 2001036933 A8 WO2001036933 A8 WO 2001036933A8 US 0031116 W US0031116 W US 0031116W WO 0136933 A8 WO0136933 A8 WO 0136933A8
Authority
WO
WIPO (PCT)
Prior art keywords
pipette tips
pipette tip
pipette
tray carrier
tip box
Prior art date
Application number
PCT/US2000/031116
Other languages
French (fr)
Other versions
WO2001036933A1 (en
Inventor
Richard A Carl
Original Assignee
Richard A Carl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richard A Carl filed Critical Richard A Carl
Priority to DE60031157T priority Critical patent/DE60031157T2/en
Priority to EP00977186A priority patent/EP1236030B1/en
Priority to JP2001538772A priority patent/JP4001746B2/en
Publication of WO2001036933A1 publication Critical patent/WO2001036933A1/en
Publication of WO2001036933A8 publication Critical patent/WO2001036933A8/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/54Supports specially adapted for pipettes and burettes
    • B01L9/543Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • B01L3/0279Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N35/1074Multiple transfer devices arranged in a two-dimensional array
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/103General features of the devices using disposable tips

Abstract

A self contained dispensing head apparatus (10) wherein a modified pipette tip box tray carrier (22) is utilized to furnish pipette tips (20), carried in a standard pipette tip box (18), by a pipette tip box tray carrier to the head apparatus and wherein means are provided to engage the pipette tip box tray carrier in a manner whereby the pipette tips are loaded into corresponding internal cylinders (13) formed in the dispense block head (26). The dispense block head comprises a solid block of material having a plurality of internal cylinders to engage the pipette tips in a sealing arrangement. The pipettes are modified from the conventional design in that a disk shaped ring portion is interposed adjacent one end of the pipette tip, a tapered end of the tip allowing a seal to be formed with the dispense block head internal cylinders.
PCT/US2000/031116 1999-11-18 2000-11-13 Dispensing apparatus having means for loading pipette tips in a dispense head WO2001036933A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60031157T DE60031157T2 (en) 1999-11-18 2000-11-13 DISPENSING DEVICE FOR LOADING PIPETTES INTO A DISPLACEMENT HEAD
EP00977186A EP1236030B1 (en) 1999-11-18 2000-11-13 Dispensing apparatus having means for loading pipette tips in a dispense head
JP2001538772A JP4001746B2 (en) 1999-11-18 2000-11-13 Dispensing device having means for loading pipette tips into a dispensing head

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/442,500 1999-11-18
US09/442,500 US6415669B1 (en) 1998-04-09 1999-11-18 Dispensing apparatus having means for loading pipette tips in a dispense head

Publications (2)

Publication Number Publication Date
WO2001036933A1 WO2001036933A1 (en) 2001-05-25
WO2001036933A8 true WO2001036933A8 (en) 2001-06-21

Family

ID=23757031

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031116 WO2001036933A1 (en) 1999-11-18 2000-11-13 Dispensing apparatus having means for loading pipette tips in a dispense head

Country Status (6)

Country Link
US (5) US6415669B1 (en)
EP (1) EP1236030B1 (en)
JP (3) JP4001746B2 (en)
AT (1) ATE341755T1 (en)
DE (1) DE60031157T2 (en)
WO (1) WO2001036933A1 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6415669B1 (en) * 1998-04-09 2002-07-09 Ccs Packard, Inc. Dispensing apparatus having means for loading pipette tips in a dispense head
US7267801B2 (en) * 1999-06-03 2007-09-11 Beckman Coulter, Inc. Pipette tip box shucking method and apparatus
JP2001033463A (en) * 1999-07-23 2001-02-09 Cosmo Tec:Kk Liquid-dispenser
US6905657B2 (en) * 2000-04-05 2005-06-14 Bioprocessors Corp. Methods and devices for storing and dispensing liquids
JP4271835B2 (en) * 2000-08-18 2009-06-03 アークレイ株式会社 Pipette device
DE10135963B4 (en) * 2001-07-24 2005-09-29 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Device for pipetting a liquid
US6793891B2 (en) * 2002-04-08 2004-09-21 Felxi Yiu Pipettor and externally sealed pipette tip
US6780381B2 (en) 2002-04-08 2004-08-24 Felix H. Yiu Pipettor and externally sealed pipette tip
AU2002351499A1 (en) * 2002-04-08 2003-10-27 Felix H. Yiu Improved pipettor and externally sealed pipette tips
US6997066B2 (en) 2002-08-07 2006-02-14 Perkinelmer Las, Inc. Dispensing apparatus
JP3733942B2 (en) * 2002-10-03 2006-01-11 松下電器産業株式会社 Dispensing device and dispensing tip removal method in dispensing device
US20040071602A1 (en) * 2002-10-15 2004-04-15 Yiu Felix H. Pipettor head adapter
FI120861B (en) * 2002-11-08 2010-04-15 Biohit Oyj multichannel pipette
US7968056B2 (en) * 2004-05-10 2011-06-28 Joe Stockwell Method and apparatus for transferring pipette tips
US20050265900A1 (en) * 2004-05-27 2005-12-01 Gard Douglas J Pipetting system with selective pipette tip loading
CA2512353A1 (en) * 2004-07-16 2006-01-16 Stemcell Technologies Inc. Automated pipette machine
US7219567B2 (en) * 2005-01-05 2007-05-22 Bio-Magnetics Ltd. Combinatorial pipettor device
US8697012B2 (en) * 2005-05-17 2014-04-15 Musashi Engineering, Inc. High-speed automatic dispensing device with replaceable dispensing head and dispensing station
US7985375B2 (en) * 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
US8703492B2 (en) 2007-04-06 2014-04-22 Qiagen Gaithersburg, Inc. Open platform hybrid manual-automated sample processing system
US8117925B2 (en) * 2007-07-06 2012-02-21 Yiu Felix H Apparatus and method for using a tip collar on pipette tips providing structural rigidity
US20090071267A1 (en) * 2007-09-17 2009-03-19 Greg Mathus Pipette tip ejection mechanism
US8726745B2 (en) * 2007-11-26 2014-05-20 Perkinelmer Health Sciences, Inc. Fluid handling device with ultrasound sensor and methods and systems using same
US8029742B2 (en) 2008-05-05 2011-10-04 Integra Biosciences Corp. Multi-channel pipettor with repositionable tips
US9339810B2 (en) 2008-05-05 2016-05-17 Integra Biosciences Ag Multi-channel pipettor with repositionable tips
US9953141B2 (en) 2009-11-18 2018-04-24 Becton, Dickinson And Company Laboratory central control unit method and system
KR101307978B1 (en) 2010-01-08 2013-09-13 (주)바이오니아 automatic purification apparatus for biological sample preparation
US9486803B2 (en) 2010-01-22 2016-11-08 Biotix, Inc. Pipette tips
US10119112B2 (en) * 2010-03-02 2018-11-06 Universite Technologie de Compiegne—UTC Multi-reactor unit for dynamic cell culture
WO2011110141A1 (en) * 2010-03-11 2011-09-15 Cybio Ag Pipetting unit and pipettor comprising such a pipetting unit, and pipette tip for use with such a pipettor
DE202010003532U1 (en) 2010-03-11 2010-07-01 Cybio Ag Pipetting unit and pipettor, comprising such a pipette unit, and pipette tip for use with such a pipettor
KR101198007B1 (en) * 2010-12-20 2012-11-05 삼성전기주식회사 Micro-ejector
US8795606B2 (en) 2012-05-30 2014-08-05 Biotix, Inc. Integrated pipette tip devices
US9086394B2 (en) * 2012-10-24 2015-07-21 Accel Biotech, Inc. Multi-function dispense head
CH708139A2 (en) * 2013-06-06 2014-12-15 Tecan Trading Ag Pipetting.
JP5910946B2 (en) 2013-08-29 2016-04-27 株式会社安川電機 Robot system and method for manufacturing processed specimen
US9868555B2 (en) * 2014-04-28 2018-01-16 Robert F. LiVolsi Systems and methods for filling inoculations
CN104020306B (en) * 2014-06-10 2016-02-24 南京裕隆生物医学发展有限公司 A kind of sample loading gun head stowage and device
DE102016111910A1 (en) * 2016-06-29 2018-01-04 Eppendorf Ag Dosing head, dosing device comprising a dosing head and method for dosing by means of a dosing head
WO2018132376A1 (en) * 2017-01-13 2018-07-19 Beckman Coulter, Inc. Motion systems for loading tips
US20200122136A1 (en) 2017-05-17 2020-04-23 Biotix, Inc. Ergonomic pipette tips
US10758909B2 (en) * 2017-07-25 2020-09-01 Thomas A. HEDGLIN Device to assist in manual transfer of pipette tips

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4158035A (en) * 1978-03-15 1979-06-12 Byrd William J Multiple sample micropipette
FI57542C (en) * 1978-06-02 1980-09-10 Suovaniemi Finnpipette VOLUMREGLERBAR PIPETT
US4565100A (en) * 1981-10-02 1986-01-21 Culture-Tek Pipette device
JPS59147268A (en) * 1983-01-21 1984-08-23 ザ パーキン―エルマー コーポレイション Method and device for automatically moving liquid sample among plurality of vessel
US4478094A (en) * 1983-01-21 1984-10-23 Cetus Corporation Liquid sample handling system
US4532805A (en) 1984-05-29 1985-08-06 Flesher Robert W Pipette system
US4933291A (en) * 1986-12-22 1990-06-12 Eastman Kodak Company Centrifugable pipette tip and pipette therefor
JPH01141467U (en) * 1988-03-24 1989-09-28
DE3921729A1 (en) * 1989-07-01 1991-01-03 Joerg Spindler Pipette plungers in grid pattern with corresp. bores - in lower plastic cylinder block and with internal spring-loaded seals
US5061449A (en) * 1989-07-25 1991-10-29 Matrix Technologies, Corp. Expandable multi-channel pipetter
US5525302A (en) * 1991-02-01 1996-06-11 Astle; Thomas W. Method and device for simultaneously transferring plural samples
JPH0669535B2 (en) * 1991-05-07 1994-09-07 幸泉 井上 Automatic chip aligner
JPH0587820A (en) 1991-09-27 1993-04-06 Hitachi Electron Eng Co Ltd Tip ejector device
JPH05119040A (en) * 1991-10-28 1993-05-14 Shimadzu Corp Sample measuring apparatus
US5232669A (en) * 1991-11-08 1993-08-03 Abbott Laboratories Pipette tip with self-aligning and self-sealing features
JPH05281237A (en) * 1992-03-31 1993-10-29 Shimadzu Corp Measuring apparatus of blood coagulation
JP2578292B2 (en) * 1992-06-30 1997-02-05 アロカ株式会社 Pipetting tip removal device for pipetting device
US5343909A (en) * 1992-12-17 1994-09-06 Jack Goodman Liquid transfer device
JPH07128343A (en) * 1993-11-04 1995-05-19 Tosoh Corp Pipette
JP2779894B2 (en) * 1994-02-14 1998-07-23 プレシジョン・システム・サイエンス株式会社 Dispensing device
JP3443201B2 (en) 1995-03-15 2003-09-02 三洋電機株式会社 Dispensing device
US5497670A (en) 1995-03-31 1996-03-12 Carl; Richard A. Liquid dispensing apparatus including means for loading pipette tips onto liquid dispensing cylinders and maintaining the loading force during the apparatus operation cycle
US5623106A (en) * 1995-06-06 1997-04-22 Johnson & Johnson Clinical Diagnostics, Inc. Method and apparatus for forming disposable tips in an analyzer
JPH0921730A (en) 1995-07-07 1997-01-21 Olympus Optical Co Ltd Dispensation nozzle cleaner for medical analyzer
US5915284A (en) * 1996-07-22 1999-06-22 Cyberlab, Inc. Multiple channel pipetting device
US6116099A (en) * 1996-11-18 2000-09-12 Carl; Richard A. Liquid dispensing apparatus having means for loading pipette tips onto fluid dispensing cylinders
CA2287962C (en) 1997-05-02 2007-01-02 Gen-Probe Incorporated Reaction receptacle apparatus
JP3316422B2 (en) 1997-06-23 2002-08-19 三洋電機株式会社 Dispensing device
US6415669B1 (en) * 1998-04-09 2002-07-09 Ccs Packard, Inc. Dispensing apparatus having means for loading pipette tips in a dispense head
JPH11295323A (en) * 1998-04-13 1999-10-29 Matsushita Electric Ind Co Ltd Automatic dispenser and its method
US6143252A (en) * 1999-04-12 2000-11-07 The Perkin-Elmer Corporation Pipetting device with pipette tip for solid phase reactions
US7267801B2 (en) * 1999-06-03 2007-09-11 Beckman Coulter, Inc. Pipette tip box shucking method and apparatus
US6368872B1 (en) * 1999-10-22 2002-04-09 Tecan Trading Ag Apparatus and method for chemical processing

Also Published As

Publication number Publication date
JP2006177948A (en) 2006-07-06
EP1236030A1 (en) 2002-09-04
US6622578B2 (en) 2003-09-23
US20020053245A1 (en) 2002-05-09
EP1236030B1 (en) 2006-10-04
DE60031157D1 (en) 2006-11-16
JP2006300968A (en) 2006-11-02
JP2003515121A (en) 2003-04-22
US20060185449A1 (en) 2006-08-24
US20030233892A1 (en) 2003-12-25
JP4482521B2 (en) 2010-06-16
US20050178217A1 (en) 2005-08-18
US6810757B2 (en) 2004-11-02
DE60031157T2 (en) 2007-08-16
WO2001036933A1 (en) 2001-05-25
US6415669B1 (en) 2002-07-09
US7536926B2 (en) 2009-05-26
JP4001746B2 (en) 2007-10-31
ATE341755T1 (en) 2006-10-15
US6978689B2 (en) 2005-12-27
EP1236030A4 (en) 2002-10-28

Similar Documents

Publication Publication Date Title
WO2001036933A8 (en) Dispensing apparatus having means for loading pipette tips in a dispense head
CN100496329C (en) Refill container
AR040619A1 (en) PLASTIC CLOSURE WITH ROTATION INHIBITION APPENDICES AND CLOSURE CONTAINER FOR THE PLACEMENT OF SUCH CLOSURE
WO2003064271A3 (en) Pipette tip container
EP1225050A3 (en) Ink container having a substantially T-shaped partitioning wall
CA2350805A1 (en) Discharge cap for releasable tablet
EP1270435A3 (en) Closure member for a bottle
ATE519602T1 (en) LIQUID DISCHARGE PRINT HEAD AND LIQUID DISCHARGE PRINTING DEVICE
GB9714996D0 (en) Containers
BRPI0514525A (en) bottleneck container closure assembly
CA2124155A1 (en) Packing Case and Opening Method Therefor
AU3341597A (en) Reclosable container and method for manufacturing it
KR19980702415A (en) Seal and syringe combination
WO2000071669A8 (en) Device for performing analyses on cell-cultures
DE69327088D1 (en) Dispenser for flowable substances
BR9812064A (en) Mechanism of vacuum packaging, and, process of packaging particulate materials in a container
EP0829774A3 (en) Toner container cap, toner container, and process cartridge
WO1998021052A3 (en) Fluid dispensing utensil
EP1427534A4 (en) A multi-compartment reagent container having means to inhibit re-use thereof
CA2315068A1 (en) Loading plant for loading a means of transport with bulk material
CA2237360A1 (en) Dispensing cap for a liquid container
CA2489015A1 (en) Pressurized dispensing package and method for using the same
DE60029408D1 (en) DEAN ANIMAL CENTRIFUGE
USD421390S (en) Shaped dual compartment bottle and package therefor
AU2001262054A1 (en) Tank system for bulk material which can be loaded with a combustible gas and which consists of fine to minute solids, and a device for discharging the bulk material

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

AK Designated states

Kind code of ref document: C1

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT. BUL. 21/2001 UNDER "PUBLISHED", DELETE "WITH AN INDICATION IN RELATION TO A PRIORITY CLAIM CONSIDERED NOT TO HAVE BEEN MADE."

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref country code: JP

Ref document number: 2001 538772

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 2000977186

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000977186

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2000977186

Country of ref document: EP