WO2001035870A1 - Dispositif de remplacement d'une valve cardiaque par voie percutanee - Google Patents

Dispositif de remplacement d'une valve cardiaque par voie percutanee Download PDF

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Publication number
WO2001035870A1
WO2001035870A1 PCT/FR2000/003176 FR0003176W WO0135870A1 WO 2001035870 A1 WO2001035870 A1 WO 2001035870A1 FR 0003176 W FR0003176 W FR 0003176W WO 0135870 A1 WO0135870 A1 WO 0135870A1
Authority
WO
WIPO (PCT)
Prior art keywords
blades
series
valve
elongated element
wall
Prior art date
Application number
PCT/FR2000/003176
Other languages
English (en)
Inventor
Jacques Seguin
Original Assignee
Jacques Seguin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE60017189T priority Critical patent/DE60017189T2/de
Priority to CA002389713A priority patent/CA2389713C/fr
Priority to US10/130,355 priority patent/US6830584B1/en
Priority to AU17132/01A priority patent/AU767710B2/en
Priority to AT00979740T priority patent/ATE285729T1/de
Priority to JP2001537666A priority patent/JP2003513751A/ja
Priority to EP00979740A priority patent/EP1233731B1/fr
Application filed by Jacques Seguin filed Critical Jacques Seguin
Publication of WO2001035870A1 publication Critical patent/WO2001035870A1/fr
Priority to US10/412,634 priority patent/US7018406B2/en
Priority to US11/352,614 priority patent/US7329278B2/en
Priority to US11/434,506 priority patent/US20070043435A1/en
Priority to US12/029,031 priority patent/US10219901B2/en
Priority to US12/348,892 priority patent/US7892281B2/en
Priority to US12/494,060 priority patent/US8016877B2/en
Priority to US12/636,563 priority patent/US8603159B2/en
Priority to US13/010,010 priority patent/US9066799B2/en
Priority to US13/104,828 priority patent/US8801779B2/en
Priority to US14/177,811 priority patent/US9962258B2/en
Priority to US14/177,806 priority patent/US8998979B2/en
Priority to US14/449,551 priority patent/USRE45865E1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/2436—Deployment by retracting a sheath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/0218—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors for minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves

Definitions

  • the present invention relates to a device for replacing a heart valve by percutaneous route.
  • the replacement of a defective heart valve is currently, most frequently, carried out by opening the thorax, putting the patient on extra-corporal circulation, temporary cardiac arrest, and opening the heart, with a view to excision and replacement of the valve.
  • the invention aims to provide a device giving all satisfaction with regard to the excision and replacement of the valve, allowing intervention without opening the chest, cardiac arrest and / or opening of the heart, and to prevent any diffusion into the circulatory system of fragments of the valve removed.
  • distal and proximal used below to describe the invention are defined with respect to the direction of flow of the blood.
  • the device according to the invention comprises:
  • a second series of blades arranged consecutively to said first series of blades in the distal direction; the blades of this second series of blades have a structure identical to that of the blades of said first series of blades, except that these blades of this second series are connected to the elongated element by their distal longitudinal ends and each have a cutting edge at the level of their proximal longitudinal end; - Means for bringing the blades of said first and second series of blades from their folding position to their unfolding position;
  • the device according to the invention can be introduced percutaneously into said body duct and be slid into this duct until each of the series of aforementioned blades is placed on one side of the valve. This position is marked using said locating means.
  • a peripheral perfusion or extracorporeal circulation system can be set up to facilitate the flow of blood, in order to prevent stagnation of blood in the heart.
  • the blades of the two series of blades are deployed, then these two series are brought closer to each other until the valve is cut off.
  • the conformation of these blades makes it possible to carry out this section in a single operation, therefore without generating fragments capable of being diffused in the circulatory system, or at least by generating very few such fragments; this conformation also allows precise control of the diameter according to which the native valve is sectioned, for the subsequent calibration of the prosthetic valve.
  • the blades are then returned to the folded position.
  • the prosthetic valve is then put in place.
  • the device according to the invention comprises a proximal prosthetic valve, with a radially deployable structure, this prosthetic valve being able to occupy a folding position, in which it is located near the wall of said elongated element and does not obstruct the introduction and sliding of the device in said body duct, and an unfolding position, in which it bears against the wall of this duct and is able to replace the native heart valve.
  • the device thus makes it possible to introduce and position the prosthetic valve at the appropriate place in the body conduit, by the same gesture as that making it possible to cut the native valve. After cutting the latter, the device is slid axially in the distal direction in order to bring the prosthetic valve to the appropriate level in this conduit, after which this prosthetic valve is deployed. The device is then removed and the severed native valve is recovered.
  • said elongate support member is a tubular catheter. This catheter thus allows the flow of blood through it the time of the excision of the native valve.
  • the section of the conduit of this catheter may be sufficient to allow the flow of blood through this conduit, which limits or avoids the need to put the patient into extracorporeal circulation.
  • the catheter can also have a reduced diameter, which facilitates the introduction and the sliding of the device in the body conduit, but it is then necessary to ensure the peripheral circulation by an external assistance system, such as a delivery system. extra-corporeal circulation.
  • the catheter has a lateral distal opening to allow blood to reach the body conduit, for example the ascending aorta, this opening being arranged so that the length of catheter through which the blood passes is as short as possible.
  • the device comprises a distal inflatable balloon, placed at the level of the external face of said elongated element; this balloon is shaped so as to be able to occupy a folding position, in which it has a section such that it does not prevent the device from sliding into said body duct, and an unfolding position, in which it occupies the 'the whole of the space existing between the outer face of said elongated element and the wall of said body duct and comes, by a peripheral edge which it comprises, to bear against this wall.
  • the balloon is inflated after positioning the series of blades on either side of the native valve, to prevent backflow of blood during the ablation of the native valve.
  • said elongated element is a catheter, this balloon also makes it possible to cause this blood to flow only through the catheter.
  • the device comprises a distal filter made of flexible material, placed at the level of the external face of said elongated element; this filter is shaped to be able to occupy a folding position, in which it has a section such that it does not prevent the introduction and sliding of the device in said body duct, and an unfolding position, in which it occupies the 'all of the space existing between the outer face of said elongated element and the wall of this conduit and comes, by a peripheral edge which it comprises, abuts against this wall.
  • This filter makes it possible to capture any fragments generated by the excision of the valve, and to retain them so that they are removed from the blood circulation.
  • the device may include means making it possible to move said series of blades in the axial direction independently of said balloon and / or said filter. Once deployed, this or these need not be moved axially in the body duct during the above-mentioned axial displacement of the series of blades.
  • Said balloon and / or said filter can also be separated from the device, by being mounted on an elongate support element which is specific to them.
  • this balloon and / or this filter are introduced into the aorta by peripheral arterial route, and the device is meanwhile introduced into the heart by the peripheral venous system, up to the right atrium then in the left atrium through the interatrial septum, up to the level of the mitral valve.
  • the prosthetic valve can advantageously comprise an armature made of shape memory material, in particular of nickel-titanium alloy known under the name "NITINOL".
  • valves made of biological material preserved animal or human valves
  • valves made of synthetic material such as polymer
  • Figure 1 is a longitudinal sectional view, according to a first embodiment for the treatment of an aortic valve;
  • Figure 2 is a cross-sectional view along the line II-II of Figure 1;
  • Figure 3 is a view similar to Figure 2, in another position of a sub-assembly which it comprises;
  • Figure 4 is a perspective view of a prosthetic valve which it allows the establishment;
  • Figures 5 to 9 are views while it is positioned in a heart, at the valve to be treated, during different successive operations by which this valve is cut and the prosthetic valve shown in Figure 4 is put in place ;
  • Figure 10 is a view of the prosthetic valve shown in Figure 4, after installation, and
  • Figure 1 1 is a view of the device according to another embodiment, for the treatment of a mitral valve.
  • Figures 1 to 3 show a device 1 for replacing a heart valve percutaneously.
  • This device comprises a tubular catheter 2 formed by three tubes 5, 6, 7 engaged one inside the other on which are placed, from the proximal side to the distal side (considered with respect to the flow of blood, i.e. say from right to left of FIG. 1), a prosthetic valve 10, two sets of blades 11, 12, a balloon 13 and a filter 14.
  • the three tubes 5, 6, 7 are slidably mounted one inside the other.
  • the inner tube 5 defines a conduit 15 whose cross section is sufficient to allow the flow of blood through it.
  • the intermediate tube 6 forms a tulip 6a delimiting, with the inner tube 5, an annular cavity 17 in which the prosthetic valve 10 is contained in the folded state.
  • FIG. 4 shows that this valve 10 comprises a frame 20 and valves 21 mounted in a functionally mobile manner on this frame 20.
  • the frame is formed by assembling wires 22, 23, 24 of shape memory material, in particular of nickel-titanium alloy known under the name "NITINOL", namely: - a wire 22 of proximal end, presenting 'deployed state of the valve 10 a substantially circular shape; a wire 23 at the distal end forming three corrugations in the axial direction, these corrugations being regularly distributed over the circumference of the valve 10, and
  • NITINOL nickel-titanium alloy known under the name
  • the valves 21, for their part, are made of biological material (preserved animal or human valves), or of synthetic material, such as a polymer.
  • the armature 20 can, when its material is cooled, be contracted radially so that the valve 10 can enter the cavity 1 7. When this material is warmed to body temperature, this armature 20 regains its shape d 'origin, shown in Figure 4, in which it has a diameter adapted to that of the body conduit, in particular the aorta, in which is the native valve to be treated. This diameter of the frame 20 is such that the valve 10 bears against the wall of the body duct and is immobilized in the axial direction relative to the latter.
  • Each series of blades 1 1, 1 2 comprises elongated metal blades 30 and an inflatable balloon 31 situated between the catheter 2 and these blades 30.
  • the blades 30 have a curved profile and are arranged around the circumference of the catheter 2.
  • the blades 30 of the proximal series 1 1 are pivotally connected to the tube 6 by their proximal ends and include a sharp distal edge 30a, while the blades 30 of the distal series 1 2 are pivotally connected to the outer tube 7 by their distal ends and include a sharp proximal edge 30b.
  • connection of the blades 30 to the tubes 6 and 7 respectively is carried out by welding the ends of the blades 30 together so as to form a ring, this ring being fixed axially to the tube 6, 7 corresponding by crimping this ring on this tube 6 , 7, the pivoting of the blades 30 being achieved by simple elastic deformation of these blades 30.
  • This pivoting is possible between a folding position of the blades 30, radially internal relative to the catheter 2, shown in Figures 1 and 2, and an unfolding position of these blades 30, radially external with respect to this catheter 2, shown in Figure 3.
  • the blades 30 are located near the wall of the tube 6 and are partially overlap each other so that they do not prevent the introduction and sliding of the device 1 in the body conduit in which the native valve to be treated is located; in said unfolding position, the blades 30 are deployed in a corolla such that their sharp edges 30a, 30b are placed in the extension of each other and thus constitute a sharp circular edge, visible in FIG. 3.
  • Each balloon 31, placed between the tube 6 and the blades 30, can be inflated from the end of the catheter 2 which leaves the patient, by a conduit 32 arranged in the tube 6. It thus makes it possible, when inflated, to 'bring the blades 30 from their folding position to their unfolding position, and vice versa when it is deflated.
  • the axial sliding of the tube 6 relative to the tube 7 makes it possible to move the series of blades 1 1, 1 2 axially in the direction of one another, between positions of mutual separation, shown in FIG. 1, and mutual ruzement.
  • a series of blades 1 1 can be placed axially on one side of the native valve while the other series of blades 1 2 is placed axially on the other side of this valve, while in the second of these positions, the sharp circular edges of these two series of blades 1 1, 1 2 are brought into mutual contact and thus cut the native valve so as to separate it from said body conduit.
  • the tubes 5 to 7 also include marks (not visible in the figures) with barium sulphate, allowing the percutaneous identification of the axial position of the device 1 relative to the native valve, so that each of the two series of blades 1 1, 1 2 can be placed on an axial side of this valve.
  • These tubes 5 to 7 also include lateral distal openings (not shown) to allow blood to reach the body duct, these openings being arranged so that the length of catheter 2 through which the blood passes is as short as possible, c that is to say immediately afterwards, in the distal direction, the filter 14.
  • the balloon 1 3 is placed on the outer face of the tube 7, distally with respect to the series 1 2.
  • This balloon 1 3 has an annular shape and is shaped to be able to occupy a folding position in which it has a section such that it does not prevent the introduction and sliding of the device 1 in said body duct, and an unfolding position, in which it occupies all of the space existing between the outer face of the tube 7 and the wall of said duct body and comes, by a peripheral edge 1 3a which it comprises, to bear against this wall.
  • the filter 14 is placed distally of the balloon 1 3, on the tube 7, to which it is fixed axially.
  • This filter 14 is made of flexible material, for example polyester mesh, and is shaped to be able to occupy a folding position in which it has a section such that it does not prevent the introduction and sliding of the device 1 in said body duct, and an unfolding position in which it occupies all of the space existing between the outer face of the catheter 2 and the wall of this duct and comes, by a peripheral edge 14a which it comprises, abuts against this wall.
  • An inflatable balloon 35 is placed between the tube 7 and the filter 14 in order, depending on whether it is inflated or deflated, to bring the filter 14 into its respective unfolding and folding positions.
  • aorta 2 is located in the heart, preferably in the left ventricle, while the aforementioned distal lateral openings are placed in a peripheral arterial vessel, preferably in the ascending aorta.
  • the balloons 1 3 and 35 are inflated so as to cause the blood to flow only through the conduit 1 5 and to prevent the back flow of blood during the ablation of the valve 55.
  • a peripheral perfusion system is put in place. place to facilitate this flow.
  • the blades 30 of the two series 1 1, 1 2 are then deployed
  • the blades 30 are then brought back to the folding position by deflating the balloons 31 while remaining in their approximation position, which keeps the valve 55 cut between them.
  • the device 1 is then slid axially in the distal direction in order to bring the tulip 6a to the appropriate level in the conduit 50 (FIG. 8), after which the valve 10 is deployed by sliding the tube 6 relative to the tube 5 (FIG. 9) ).
  • the balloons 1 3 and 35 are deflated, then the device 1 is removed and the severed valve 55 is recovered (FIG. 10).
  • Figure 1 1 shows a second embodiment of the device 1, allowing intervention on a mitral valve 56.
  • the same reference numbers are used to designate the same elements or parts as above, since these elements or parts are identical or similar between the two embodiments.
  • the tubular catheter is replaced by a support wire 2, on which one of the series of blades is mounted and by a tube engaged and able to slide on this wire, on which the other of the series of blades is mounted.
  • the inflation conduits of the balloons 31 run along these support wires and tubes
  • the balloon 1 3 and the filter 14 are separated from the device 1 and are introduced into the aorta by peripheral arterial route, by means of a support wire 40, along which the inflation ducts of the balloons 1 3 and 35 pass.
  • the device 1, devoid of balloon 13 and filter 14 is meanwhile introduced into the heart by the peripheral venous system, up to the right atrium and then into the left atrium through the interatrial septum, up to at valve 56.
  • the device 1 For the rest, the device 1 operates in the same manner as above.
  • the invention thus provides a device for replacing a heart valve by percutaneous route, making it possible to remedy the drawbacks of the prior techniques.
  • the device 1 gives all satisfaction with regard to the excision of the valve 55, 56, by making it possible to intervene without cardiac arrest and to prevent, thanks to the filter 14, any diffusion into the circulatory system of fragments of the valve 55, 56.
  • the device can comprise a fourth tube, engaged and able to slide on the tube 7, this fourth tube comprising the balloon and the filter mounted on it and making it possible to move said series of blades in the axial direction independently of said balloon and / or said filter;
  • the blades can be rectilinear as shown in the drawing or be curved towards the axis of the device at their end including the cutting edge, so as to eliminate any risk of injury to the wall of the body duct, as shown in Figure 1 2 ;
  • the filter 14 can be of the self-expanding type and can normally be held in the retracted position by a sliding tube, which covers it, which makes the balloon 35 unnecessary.

Abstract

Ce dispositif (1) comprend : un élément allongé (2) de support; deux séries (11, 12) de lames allongées (30), disposées autour de la circonférence de l'élément allongé (2); ces lames (30) présentent des bords tranchants (30a, 30b) en regard et peuvent être déployées en corolle de telle sorte que leurs bords tranchants soient placés dans le prolongement les uns des autres et constituent ainsi des bords circulaires tranchants; ces lames (30) peuvent être rapprochées de telle sorte que leurs bords circulaires tranchants viennent sectionner la valve native (55, 56) de manière à la séparer dudit conduit corporel (50).

Description

DISPOSITIF DE REMPLACEMENT D'UNE VALVE CARDIAQUE PAR VOIE PERCUTANEE
La présente invention concerne un dispositif de remplacement d'une valve cardiaque par voie percutanée. Le remplacement d'une valve cardiaque défectueuse est actuellement, le plus fréquemment, réalisé par ouverture du thorax, mise du patient sous circulation extra-corporelle, arrêt cardiaque temporaire, et ouverture du cœur, en vue de l'exérèse et du remplacement de la valve.
Ces étapes successives de l'opération ont pour inconvénient d'impliquer une hospitalisation relativement longue du patient, et d'être complexe et coûteuse.
Pour remédier à cet inconvénient, il a été envisagé de remplacer une valve cardiaque par voie peu invasive. Les demandes internationales (PCT) n ° WO 93/01768 et WO 97/28807, ainsi que les brevets américains n ° 5 814 097, 5 370 685 ou 5 545 214 illustrent des techniques peu invasives connues ainsi que des instruments de mise en oeuvre de ces techniques.
Les techniques existantes sont toutefois considérées comme n'étant pas parfaitement satisfaisantes et comme susceptibles d'être améliorées. En particulier, ces techniques ont pour inconvénient d'imposer en tout état de cause la mise du patient sous circulation extra-corporelle et l'arrêt temporaire du cœur ; elles sont difficiles à mettre en pratique ; elles ne permettent pas un contrôle précis du diamètre selon lequel la valve native est coupée, en vue du calibrage ultérieur de la valve prothétique ; elles entraînent des risques de diffusion de fragments de valve native, souvent calcifiée, dans l'organisme, qui peuvent conduire à une embolie, ainsi que des risques de perforation de la paroi aortique ou cardiaque ; elles induisent en outre des risques de reflux aigus du sang lors de l'ablation de la valve native. Le dispositif selon la présente invention a été conçu dans le but de pallier les insuffisances de ces techniques.
En particulier, l'invention a pour objectif de fournir un dispositif donnant toute satisfaction en ce qui concerne l'exérèse et le remplacement de la valve, en permettant d'intervenir sans ouverture du thorax, arrêt cardiaque et/ou ouverture du cœur, et de prévenir toute diffusion dans le système circulatoire de fragments de la valve retirée. Les termes "distal" et "proximal" utilisés ci-après pour exposer l'invention sont définis par rapport au sens d'écoulement du sang. Le dispositif selon l'invention comprend :
- un élément allongé de support ; - une première série de lames allongées, disposées autour de la circonférence dudit élément allongé ; ces lames sont reliées de manière pivotante à l'élément allongé au niveau de leurs extrémités longitudinales proximales et présentent chacune un bord tranchant au niveau de leur extrémité longitudinale distale ; ces lames peuvent pivoter par rapport à l'élément allongé entre une position de repliage, dans laquelle elles se trouvent près de la paroi de l'élément allongé de telle sorte qu'elles ne font pas obstacle à l'introduction et au coulissement du dispositif dans le conduit corporel dans lequel se trouve la valve, en particulier dans l'aorte, et une position de dépliage, dans laquelle ces lames sont déployées en corolle de telle sorte que leurs bords tranchants sont placés dans le prolongement les uns des autres et constituent ainsi un bord circulaire tranchant ;
- une deuxième série de lames, disposée consécutivement à ladite première série de lames dans la direction distale ; les lames de cette deuxième série de lames ont une structure identique à celle des lames de ladite première série de lames, sinon que ces lames de cette deuxième série sont reliées à l'élément allongé par leurs extrémités longitudinales distales et présentent chacune un bord tranchant au niveau de leur extrémité longitudinale proximale ; - des moyens permettant d'amener les lames desdites première et deuxième séries de lames de leur position de repliage à leur position de dépliage ;
- des moyens permettant de déplacer axialement lesdites séries de lames en direction l'une de l'autre, entre une position d'éloignement mutuel de ces séries de lames, dans laquelle une série de lames peut être placée axialement d'un côté de la valve native tandis que l'autre série de lames est placée axialement de l'autre côté de cette valve, et une position de rapprochement, dans laquelle les bords circulaires tranchants de ces deux séries de lames sont amenés en contact mutuel et viennent ainsi sectionner la valve native de manière à la séparer dudit conduit corporel ; et - des moyens de repérage par voie percutanée de la position axiale du dispositif par rapport à la valve native, permettant de positionner chacune des deux séries de lames précitées d'un côté de cette valve.
Le dispositif selon l'invention peut être introduit par voie percutanée dans ledit conduit corporel et être coulissé dans ce conduit jusqu'à ce que chacune des séries de lames précitées soit placée d'un côté de la valve. Cette position est repérée à l'aide desdits moyens de repérage. Un système de perfusion périphérique ou de circulation extracorporelle peut être mis en place pour faciliter l'écoulement du sang, en vue d'empêcher la stagnation du sang dans le cœur.
Après le positionnement précité du dispositif, les lames des deux séries de lames sont déployées, puis ces deux séries sont rapprochées l'une de l'autre jusqu'à sectionner la valve. La conformation de ces lames permet de réaliser cette section en une seule opération, donc sans générer de fragments susceptibles d'être diffusés dans le système circulatoire, ou tout au moins en ne générant que très peu de tels fragments ; cette conformation permet en outre un contrôle précis du diamètre selon lequel la valve native est sectionnée, en vue du calibrage ultérieur de la valve prothétique. Les lames sont ensuite ramenées en position de repliage.
La valve prothétique est alors mise en place.
Cette valve peut être séparée du dispositif, auquel cas ce dernier est retiré puis la valve prothétique est introduite et positionnée dans ledit conduit corporel au moyen d'un dispositif distinct. De préférence toutefois, le dispositif selon l'invention comprend une valve prothétique proximale, à structure radialement déployable, cette valve prothétique pouvant occuper une position de repliage, dans laquelle elle se trouve près de la paroi dudit élément allongé et ne fait pas obstacle à l'introduction et coulissement du dispositif dans ledit conduit corporel, et une position de dépliage, dans laquelle elle prend appui contre la paroi de ce conduit et est à même de remplacer la valve cardiaque native.
Le dispositif permet ainsi d'introduire et de positionner la valve prothétique à l'endroit adéquat dans le conduit corporel, par le même geste que celui permettant de sectionner la valve native. Après sectionnement de cette dernière, le dispositif est coulissé axialement dans la direction distale afin d'amener la valve prothétique au niveau adéquat dans ce conduit, après quoi cette valve prothétique est déployée. Le dispositif est ensuite retiré et la valve native sectionnée est récupérée.
De préférence, ledit élément allongé de support est un cathéter tubulaire. Ce cathéter permet ainsi l'écoulement du sang au travers de lui le temps de l'exérèse de la valve native.
La section du conduit de ce cathéter peut être suffisante pour permettre l'écoulement du sang au travers de ce conduit, ce qui limite ou évite le recours à une mise du patient en circulation extra-corporelle. Le cathéter peut aussi avoir un diamètre réduit, ce qui facilite l'introduction et le coulissement du dispositif dans le conduit corporel, mais il est alors nécessaire d'assurer la circulation périphérique par un système externe d'assistance, telle qu'un système de circulation extra-corporelle.
Le cathéter comprend une ouverture distale latérale pour permettre au sang de rejoindre le conduit corporel, par exemple l'aorte ascendante, cette ouverture étant aménagée de manière à ce que la longueur de cathéter traversée par le sang soit la plus courte possible.
De préférence, le dispositif comprend un ballonnet gonflable distal, placé au niveau de la face extérieure dudit élément allongé ; ce ballonnet est conformé pour pouvoir occuper une position de repliage, dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction au coulissement du dispositif dans ledit conduit corporel, et une position de dépliage, dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure dudit élément allongé et la paroi dudit conduit corporel et vient, par un bord périphérique qu'il comprend, en appui contre cette paroi.
Le ballonnet est gonflé après le positionnement des séries de lames de part et d'autre de la valve native, pour empêcher le reflux du sang lors de l'ablation de la valve native. Lorsque ledit élément allongé est un cathéter, ce ballonnet permet en outre d'amener ce sang à s'écouler uniquement au travers du cathéter.
Une fois la valve prothétique mise en place, le ballonnet est ramené en position de repiiage de manière à rétablir le flux sanguin au travers du conduit corporel. De préférence, le dispositif comprend un filtre distal en matériau souple, placé au niveau de la face extérieure dudit élément allongé ; ce filtre est conformé pour pouvoir occuper une position de repliage, dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction et au coulissement du dispositif dans ledit conduit corporel, et une position de dépliage, dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure dudit élément allongé et la paroi de ce conduit et vient, par un bord périphérique qu'il comprend, en appui contre cette paroi.
Ce filtre permet de capter les éventuels fragments générés par l'exérèse de la valve, et de les retenir afin qu'ils soient retirés de la circulation sanguine.
Le dispositif peut comprendre des moyens permettant de déplacer lesdites séries de lames dans le sens axial indépendamment dudit ballonnet et/ou dudit filtre. Une fois déployés, ce ou ces derniers n'ont pas à être déplacés axialement dans le conduit corporel lors du déplacement axial précité des séries de lames.
Ledit ballonnet et/ou ledit filtre peuvent également être séparés du dispositif, en étant montés sur un élément allongé de support qui leur est propre.
En cas d'intervention sur une valve mitrale, ce ballonnet et/ou ce filtre sont introduits dans l'aorte par voie artérielle périphérique, et le dispositif est quant à lui introduit dans le cœur par le système veineux périphérique, jusqu'à l'oreillette droite puis dans l'oreillette gauche à travers le septum inter-auriculaire, jusqu'au niveau de la valve mitrale.
La valve prothétique peut avantageusement comprendre une armature en matériau à mémoire de forme, notamment en alliage Nickel- titane connu sous la dénomination "NITINOL".
Cette même valve peut comprendre des valvules en matériau biologique (valvules animales ou humaines conservées), ou des valvules en matériau synthétique, tel qu'en polymère. Pour sa bonne compréhension, l'invention est à nouveau décrite ci-dessous en référence au dessin schématique annexé représentant, à titre d'exemple non limitatif, une forme de réalisation préférée du dispositif qu'elle concerne.
La figure 1 en est une vue coupe longitudinale, selon une première forme de réalisation destinée au traitement d'une valve aortique ; la figure 2 en est une vue en coupe transversale, selon la ligne ll-ll de la figure 1 ; la figure 3 est une vue similaire à la figure 2, dans une autre position d'un sous-ensemble qu'il comprend ; la figure 4 est une vue en perspective d'une valve prothétique dont il permet la mise en place ; les figures 5 à 9 en sont des vues alors qu'il est positionné dans un coeur, au niveau de la valve à traiter, au cours de différentes opérations successives par lesquelles cette valve est sectionnée et la valve prothétique montrée à la figure 4 est mise en place ; la figure 10 est une vue de la valve prothétique montrée à la figure 4, après mise en place, et la figure 1 1 est une vue du dispositif selon une autre forme de réalisation, destinée au traitement d'une valve mitrale. Les figures 1 à 3 représentent un dispositif 1 de remplacement d'une valve cardiaque par voie percutanée.
Ce dispositif comprend un cathéter tubulaire 2 formé de trois tubes 5, 6, 7 engagés les uns dans les autres sur lesquels sont placés, du côté proximal vers le côté distal (considérés par rapport à l'écoulement du sang, c'est-à-dire de la droite vers la gauche de la figure 1 ), une valve prothétique 10, deux séries de lames 1 1 , 12, un ballonnet 13 et un filtre 14.
Les trois tubes 5, 6, 7 sont montés coulissants les uns dans les autres. Le tube intérieur 5 délimite un conduit 15 dont la section est suffisante pour permettre l'écoulement du sang à travers lui.
Du côté proximal, le tube intermédiaire 6 forme une tulipe 6a délimitant, avec le tube intérieur 5, une cavité annulaire 17 dans laquelle est contenue la valve prothétique 10 à l'état replié.
La figure 4 montre que cette valve 10 comprend une armature 20 et des valvules 21 montées de manière fonctionnellement mobiles sur cette armature 20.
L'armature est constituée par assemblage de fils 22, 23, 24 en matériau à mémoire de forme, notamment en alliage Nickel-titane connu sous la dénomination "NITINOL", à savoir : - un fil 22 d'extrémité proximale, présentant à l'état déployé de la valve 10 une forme sensiblement circulaire ; - un fil 23 d'extrémité distale formant trois ondulations dans le sens axial, ces ondulations étant régulièrement réparties sur la circonférence de la valve 10, et
- un fil intermédiaire 24 formant des ondulations longitudinales entre les fils 22 et 23, ce fil 24 étant relié à ces derniers par les extrémités de chacune de ces ondulations.
Les valvules 21 , quant à elles, sont en matériau biologique (valvules animales ou humaines conservées), ou en matériau synthétique, tel qu'un polymère. L'armature 20 peut, lorsque son matériau est refroidi, être contractée radialement de telle sorte que la valve 10 peut entrer dans la cavité 1 7. Lorsque ce matériau est réchauffé à la température de l'organisme, cette armature 20 retrouve sa forme d'origine, représentée à la figure 4, dans laquelle elle a un diamètre adapté à celui du conduit corporel, en particulier l'aorte, dans lequel se trouve la valve native à traiter. Ce diamètre de l'armature 20 est tel que la valve 10 prend appui contre la paroi du conduit corporel et est immobilisée dans le sens axial par rapport à celui-ci.
Chaque série de lame 1 1 , 1 2 comprend des lames allongées métalliques 30 et un ballonnet gonflable 31 situé entre le cathéter 2 et ces lames 30.
Les lames 30 ont un profil incurvé et sont disposées sur la circonférence du cathéter 2.
Les lames 30 de la série proximale 1 1 sont reliées de manière pivotante au tube 6 par leurs extrémités proximales et comprennent un bord distal tranchant 30a, tandis que les lames 30 de la série distale 1 2 sont reliées de manière pivotante au tube extérieur 7 par leurs extrémités distales et comprennent un bord proximal tranchant 30b.
La liaison des lames 30 aux tubes 6 et 7 respectivement, est réalisée par soudage des extrémités des lames 30 entre elles de manière à former un anneau, cet anneau étant fixé axialement au tube 6, 7 correspondant par sertissage de cet anneau sur ce tube 6, 7, le pivotement des lames 30 étant réalisé par simple déformation élastique de ces lames 30. Ce pivotement est possible entre une position de repliage des lames 30, radialement interne par rapport au cathéter 2, montrée aux figures 1 et 2, et une position de dépliage de ces lames 30, radialement externe par rapport à ce cathéter 2, montrée à la figure 3. Dans la position de repliage, les lames 30 se trouvent près de la paroi du tube 6 et se recouvrent partiellement les unes les autres de telle sorte qu'elles ne font pas obstacle à l'introduction et au coulissement du dispositif 1 dans le conduit corporel dans lequel se trouve la valve native à traiter ; dans ladite position de dépliage, les lames 30 sont déployées en corolle de telle sorte que leurs bords tranchants 30a, 30b sont placés dans le prolongement les uns des autres et constituent ainsi un bord circulaire tranchant, visible sur la figure 3.
Chaque ballonnet 31 , placé entre le tube 6 et les lames 30, peut être gonflé depuis l'extrémité du cathéter 2 qui sort du patient, par un conduit 32 aménagé dans le tube 6. Il permet ainsi, lorsqu'il est gonflé, d'amener les lames 30 de leur position de repliage à leur position de dépliage, et inversement lorsqu'il est dégonflé.
Le coulissement axial du tube 6 par rapport au tube 7 permet de déplacer axialement les séries de lames 1 1 , 1 2 en direction l'une de l'autre, entre des positions d'éloignement mutuel, montrée à la figure 1 , et de rapprochement mutuel. Dans la première de ces positions, une série de lames 1 1 peut être placée axialement d'un côté de la valve native tandis que l'autre série de lames 1 2 est placée axialement de l'autre côté de cette valve, tandis que dans la deuxième de ces positions, les bords circulaires tranchants de ces deux séries de lames 1 1 , 1 2 sont amenés en contact mutuel et viennent ainsi sectionner la valve native de manière à la séparer dudit conduit corporel.
Les tubes 5 à 7 comprennent en outre des repères (non visibles sur les figures) au sulfate de baryum, permettant le repérage par voie percutanée de la position axiale du dispositif 1 par rapport à la valve native, afin que chacune des deux séries de lames 1 1 , 1 2 puisse être placée d'un côté axial de cette valve.
Ces tubes 5 à 7 comprennent également des ouvertures distales latérales (non représentées) pour permettre au sang de rejoindre le conduit corporel, ces ouvertures étant aménagée de manière à ce que la longueur de cathéter 2 traversée par le sang soit la plus courte possible, c'est-à-dire immédiatement après, dans le sens distal le filtre 14. Le ballonnet 1 3 est placé sur la face extérieure du tube 7, distalement par rapport à la série 1 2. Ce ballonnet 1 3 présente une forme annulaire et est conformé pour pouvoir occuper une position de repliage dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction et au coulissement du dispositif 1 dans ledit conduit corporel, et une position de dépliage, dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure du tube 7 et la paroi dudit conduit corporel et vient, par un bord périphérique 1 3a qu'il comprend, en appui contre cette paroi. Le filtre 14 est placé distalement par rapport au ballonnet 1 3, sur le tube 7, auquel il est fixé axialement. Ce filtre 14 est en matériau souple, par exemple en résille de polyester, et est conformé pour pouvoir occuper une position de repliage dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction et au coulissement du dispositif 1 dans ledit conduit corporel, et une position de dépliage dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure du cathéter 2 et la paroi de ce conduit et vient, par un bord périphérique 14a qu'il comprend, en appui contre cette paroi.
Un ballonnet gonflable 35 est placé entre le tube 7 et le filtre 14 pour, selon qu'il est gonflé ou dégonflé, amener le filtre 14 dans ses positions respectives de dépliage et de repliage.
En pratique, ainsi que le montrent les figures 5 à 9, le dispositif
1 est introduit par voie percutanée dans ledit conduit corporel 50 et est coulissé dans ce conduit 50 jusqu'à ce que chacune des séries 1 1 , 1 2 de lames soit placée d'un côté de la valve native 55 à traiter (figure 5). Cette position est repérée à l'aide des repères précités.
Dans cette position du dispositif, la partie proximale du cathéter
2 est située dans le cœur, préférentiellement dans le ventricule gauche, tandis que les ouvertures latérales distales précitées sont placées dans un vaisseau artériel périphérique, préférentiellement dans l'aorte ascendante.
Les ballonnets 1 3 et 35 sont gonflés de manière à amener le sang à s'écouler uniquement au travers du conduit 1 5 et à empêcher le reflux du sang lors de l'ablation de la valve 55. Un système de perfusion périphérique est mis en place pour faciliter cet écoulement. Les lames 30 des deux séries 1 1 , 1 2 sont alors déployées
(figure 6) par gonflage des ballonnets 31 , puis ces deux séries 1 1 , 12 sont rapprochées l' une de l'autre par coulissement du tube 6 par rapport au tube 7, jusqu'à sectionner la valve 55 (figure 7).
Les lames 30 sont ensuite ramenées en position de repliage par dégonflage des ballonnets 31 tout en restant dans leur position de rapprochement, ce qui permet de maintenir la valve 55 sectionnée entre elles.
Le dispositif 1 est alors coulissé axialement dans la direction distale afin d'amener la tulipe 6a au niveau adéquat dans le conduit 50 (figure 8), après quoi la valve 10 est déployée par coulissement du tube 6 par rapport au tube 5 (figure 9).
Les ballonnets 1 3 et 35 sont dégonflés puis le dispositif 1 est retiré et la valve 55 sectionnée est récupérée (figure 10) .
La figure 1 1 montre une deuxième forme de réalisation du dispositif 1 , permettant une intervention sur une valve mitrale 56. Les mêmes numéros de références sont utilisés pour désigner les mêmes éléments ou parties que précités, dès lors que ces éléments ou parties sont identiques ou similaires entre les deux formes de réalisation.
Dans ce cas, le cathéter tubulaire est remplacé par un fil de support 2, sur lequel l'une des séries de lames est montée et par un tube engagé et pouvant coulisser sur ce fil, sur lequel l'autre des séries de lames est montée ; les conduits de gonflage des ballonnets 31 cheminent le long de ces fil de support et tube ; le ballonnet 1 3 et le filtre 14 sont séparés du dispositif 1 et sont introduits dans l'aorte par voie artérielle périphérique, au moyen d'un fil de support 40, le long duquel cheminent les conduits de gonflage des ballonnets 1 3 et 35. Le dispositif 1 , dépourvu de ballonnet 13 et de filtre 14, est quant à lui introduit dans le cœur par le système veineux périphérique, jusqu'à l'oreillette droite puis dans l'oreillette gauche à travers le septum inter-auriculaire, jusqu'au niveau de la valve 56.
Pour le reste, le dispositif 1 fonctionne de la même manière que précité.
L'invention fournit ainsi un dispositif de remplacement d'une valve cardiaque par voie percutanée, permettant de remédier aux inconvénients des techniques antérieures. En effet, le dispositif 1 donne toute satisfaction en ce qui concerne l'exérèse de la valve 55, 56, en permettant d'intervenir sans arrêt cardiaque et de prévenir, grâce au filtre 14, toute diffusion dans le système circulatoire de fragments de la valve 55, 56.
Il va de soi que l'invention n'est pas limitée à la forme de réalisation décrite ci-dessus à titre d'exemple mais qu'elle en embrasse, au contraire, toutes les variantes de réalisation. Ainsi, le dispositif peut comprendre un quatrième tube, engagé et pouvant coulisser sur le tube 7, ce quatrième tube comprenant le ballonnet et le filtre montés sur lui et permettant de déplacer lesdites séries de lames dans le sens axial indépendamment dudit ballonnet et/ou dudit filtre ; les lames peuvent être rectilignes comme représentées au dessin ou être courbées vers l'axe du dispositif au niveau de leur extrémité comprenant le bord tranchant, de manière à éliminer tout risque de lésion à la paroi du conduit corporel, comme montré à la figure 1 2 ; le filtre 14 peut être du type auto- expandable et être normalement maintenu en position rétracté par un tube coulissant, qui le recouvre, ce qui rend le ballonnet 35 inutile.

Claims

REVENDICATIONS
1 - Dispositif (1 ) de remplacement par voie percutanée d'une valve cardiaque (55, 56) se trouvant dans un conduit corporel (50), caractérisé en ce qu'il comprend :
- un élément allongé (2) de support ;
- une première série ( 1 1 ) de lames allongées (30), disposées autour de la circonférence dudit élément allongé (2) ; ces lames (30) sont reliées de manière pivotante audit élément allongé (2) au niveau de leurs extrémités longitudinales proximales et présentent chacune un bord tranchant (30a) au niveau de leur extrémité longitudinale distale ; ces lames (30) peuvent pivoter par rapport audit élément allongé (2) entre une position de repliage, dans laquelle elles se trouvent près de la paroi de l'élément allongé (2) de telle sorte qu'elles ne font pas obstacle à l'introduction et au coulissement du dispositif ( 1 ) dans le conduit corporel (50) dans lequel se trouve la valve (55, 56), en particulier dans l'aorte, et une position de dépliage, dans laquelle ces lames (30) sont déployées en corolle de telle sorte que leurs bords tranchants (30a) sont placés dans le prolongement les uns des autres et constituent ainsi un bord circulaire tranchant ;
- une deuxième série ( 1 2) de lames (30), disposée consécutivement à ladite première série (1 1 ) de lames dans la direction distale ; les lames (30) de cette deuxième série ( 1 2) de lames ont une structure identique à celle des lames (30) de ladite première série (1 1 ) de lames, sinon que ces lames (30) de cette deuxième série (1 2) sont reliées audit élément allongé par leurs extrémités longitudinales distales et présentent chacune un bord tranchant (30b) au niveau de leur extrémité longitudinale proximale ;
- des moyens (31 ) permettant d'amener les lames (30) desdites première et deuxième séries ( 1 1 , 1 2) de lames de leur position de repliage à leur position de dépliage ;
- des moyens (6, 7) permettant de déplacer axialement lesdites séries ( 1 1 , 1 2) de lames en direction l'une de l'autre, entre une position d'éloignement mutuel de ces séries ( 1 1 , 1 2) de lames, dans laquelle une série (1 1 ) de lames peut être placée axialement d'un côté de la valve native (55, 56) tandis que l'autre série ( 1 2) de lames est placée axialement de l'autre côté de cette valve (55, 56), et une position de rapprochement, dans laquelle les bords circulaires tranchants de ces deux séries (1 1 , 12) de lames sont amenés en contact mutuel et viennent ainsi sectionner la valve native (55, 56) de manière à la séparer dudit conduit corporel (50) ; et - des moyens de repérage par voie percutanée de la position axiale du dispositif ( 1 ) par rapport à la valve native (55, 56), permettant de positionner chacune des deux séries (1 1 , 12) de lames précitées d'un côté de cette valve.
2 - Dispositif (1 ) selon la revendication 1 , caractérisé en ce qu'il comprend une valve prothétique proximale ( 10), à structure radialement déployable, cette valve prothétique ( 10) pouvant occuper une position de repliage, dans laquelle elle se trouve près de la paroi dudit élément allongé (2) et ne fait pas obstacle à l'introduction et coulissement du dispositif (1 ) dans ledit conduit corporel (50), et une position de dépliage, dans laquelle elle prend appui contre la paroi de ce conduit (50) et est à même de remplacer la valve cardiaque native (55, 56).
3 - Dispositif ( 1 ) selon la revendication 1 ou la revendication 2, caractérisé en ce que ledit élément allongé de support est un cathéter tubulaire (2). 4 - Dispositif ( 1 ) selon l'une des revendications 1 à 3, caractérisé en ce qu'il comprend un ballonnet gonflable distal (1 3), placé au niveau de la face extérieure dudit élément allongé (2) ; ce ballonnet ( 1 3) est conformé pour pouvoir occuper une position de repliage, dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction au coulissement du dispositif ( 1 ) dans ledit conduit corporel (50), et une position de dépliage, dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure dudit élément allongé (2) et la paroi dudit conduit corporel (50) et vient, par un bord périphérique (1 3a) qu'il comprend, en appui contre cette paroi. 5 - Dispositif ( 1 ) selon l'une des revendications 1 à 4, caractérisé en ce qu'il comprend un filtre distal ( 14) en matériau souple, placé au niveau de la face extérieure dudit élément allongé (2) ; ce filtre (14) est conformé pour pouvoir occuper une position de repliage, dans laquelle il présente une section telle qu'il ne fait pas obstacle à l'introduction et au coulissement du dispositif (1 ) dans ledit conduit corporel (50), et une position de dépliage, dans laquelle il occupe l'ensemble de l'espace existant entre la face extérieure dudit élément allongé (2) et la paroi de ce conduit (50) et vient, par un bord périphérique ( 14a) qu'il comprend, en appui contre cette paroi.
6 - Dispositif ( 1 ) selon la revendication 4 ou la revendication 5, caractérisé en ce qu'il comprend des moyens permettant de déplacer lesdites séries de lames dans le sens axial indépendamment dudit ballonnet et/ou dudit filtre.
7 - Dispositif (1 ) selon la revendication 4 ou la revendication 5, caractérisé en ce que ledit ballonnet (1 3) et/ou ledit filtre (14) sont montés sur un élément allongé de support qui leur est propre, et sont séparés du dispositif (1 ).
8 - Dispositif ( 1 ) selon l'une des revendications 2 à 7, caractérisé en ce que la valve prothétique ( 10) comprend une armature (20) en matériau à mémoire de forme, notamment en alliage Nickel-titane connu sous la dénomination "NITINOL".
9 - Dispositif (1 ) selon l'une des revendications 2 à 8, caractérisé en ce que la valve prothétique ( 10) comprend des valvules (21 ) en matériau biologique (valvules animales ou humaines conservées), ou des valvules en matériau synthétique, tel qu'en polymère. 10 - Dispositif ( 1 ) selon l'une des revendications 1 à 9, caractérisé en ce que les lames sont courbées vers l'axe du dispositif au niveau de leur extrémité comprenant le bord tranchant.
1 1 - Dispositif ( 1 ) selon l'une des revendications 3 à 10, caractérisé en ce que le cathéter comprend une ouverture distale latérale pour permettre au sang de rejoindre le conduit corporel, par exemple l'aorte ascendante, cette ouverture étant aménagée de manière à ce que la longueur de cathéter traversée par le sang soit la plus courte possible, et permette d'assurer une circulation sanguine entre le cœur et un vaisseau périphérique.
PCT/FR2000/003176 1999-11-17 2000-11-15 Dispositif de remplacement d'une valve cardiaque par voie percutanee WO2001035870A1 (fr)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DE60017189T DE60017189T2 (de) 1999-11-17 2000-11-15 Perkutane vorrichtung zum ersetzen einer herzklappe
CA002389713A CA2389713C (fr) 1999-11-17 2000-11-15 Dispositif de remplacement d'une valve cardiaque par voie percutanee
US10/130,355 US6830584B1 (en) 1999-11-17 2000-11-15 Device for replacing a cardiac valve by percutaneous route
AU17132/01A AU767710B2 (en) 1999-11-17 2000-11-15 Device for replacing a cardiac valve by percutaneous route
AT00979740T ATE285729T1 (de) 1999-11-17 2000-11-15 Perkutane vorrichtung zum ersetzen einer herzklappe
JP2001537666A JP2003513751A (ja) 1999-11-17 2000-11-15 経皮ルートによって心臓弁を交換するためのデバイス
EP00979740A EP1233731B1 (fr) 1999-11-17 2000-11-15 Dispositif de remplacement d'une valve cardiaque par voie percutanee
US10/412,634 US7018406B2 (en) 1999-11-17 2003-04-10 Prosthetic valve for transluminal delivery
US11/352,614 US7329278B2 (en) 1999-11-17 2006-02-13 Prosthetic valve for transluminal delivery
US11/434,506 US20070043435A1 (en) 1999-11-17 2006-05-15 Non-cylindrical prosthetic valve system for transluminal delivery
US12/029,031 US10219901B2 (en) 1999-11-17 2008-02-11 Prosthetic valve for transluminal delivery
US12/348,892 US7892281B2 (en) 1999-11-17 2009-01-05 Prosthetic valve for transluminal delivery
US12/494,060 US8016877B2 (en) 1999-11-17 2009-06-29 Prosthetic valve for transluminal delivery
US12/636,563 US8603159B2 (en) 1999-11-17 2009-12-11 Prosthetic valve for transluminal delivery
US13/010,010 US9066799B2 (en) 1999-11-17 2011-01-20 Prosthetic valve for transluminal delivery
US13/104,828 US8801779B2 (en) 1999-11-17 2011-05-10 Prosthetic valve for transluminal delivery
US14/177,811 US9962258B2 (en) 1999-11-17 2014-02-11 Transcatheter heart valves
US14/177,806 US8998979B2 (en) 1999-11-17 2014-02-11 Transcatheter heart valves
US14/449,551 USRE45865E1 (en) 1999-11-17 2014-08-01 Prosthetic valve for transluminal delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9914462A FR2800984B1 (fr) 1999-11-17 1999-11-17 Dispositif de remplacement d'une valve cardiaque par voie percutanee
FR99/14462 1999-11-17

Related Parent Applications (4)

Application Number Title Priority Date Filing Date
PCT/FR2000/003176 Continuation-In-Part WO2001035870A1 (fr) 1999-11-17 2000-11-15 Dispositif de remplacement d'une valve cardiaque par voie percutanee
PCT/FR2001/003258 Continuation-In-Part WO2002036048A1 (fr) 1999-11-17 2001-10-19 Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement
US10/772,101 Continuation-In-Part US8579966B2 (en) 1999-11-17 2004-02-04 Prosthetic valve for transluminal delivery
US12/348,892 Continuation-In-Part US7892281B2 (en) 1999-11-17 2009-01-05 Prosthetic valve for transluminal delivery

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US10130355 A-371-Of-International 2000-11-15
US10/130,355 Continuation-In-Part US6830584B1 (en) 1999-11-17 2000-11-15 Device for replacing a cardiac valve by percutaneous route
US10/130,355 A-371-Of-International US6830584B1 (en) 1999-11-17 2000-11-15 Device for replacing a cardiac valve by percutaneous route
PCT/FR2000/003176 Continuation-In-Part WO2001035870A1 (fr) 1999-11-17 2000-11-15 Dispositif de remplacement d'une valve cardiaque par voie percutanee
PCT/FR2001/003258 A-371-Of-International WO2002036048A1 (fr) 1999-11-17 2001-10-19 Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement
PCT/FR2001/003258 Continuation-In-Part WO2002036048A1 (fr) 1999-11-17 2001-10-19 Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement
US10/412,634 Continuation-In-Part US7018406B2 (en) 1999-11-17 2003-04-10 Prosthetic valve for transluminal delivery
US12/029,031 Continuation-In-Part US10219901B2 (en) 1999-11-17 2008-02-11 Prosthetic valve for transluminal delivery
US12/636,563 Continuation-In-Part US8603159B2 (en) 1999-11-17 2009-12-11 Prosthetic valve for transluminal delivery

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Cited By (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1702247A2 (fr) * 2003-12-23 2006-09-20 Sadra Medical, Inc. Valvule cardiaque repositionnable
EP1701668A1 (fr) * 2003-12-23 2006-09-20 Sadra Medical, Inc. Appareils et procedes de protection contre une embolisation au cours du remplacement endovasculaire de la valvule cardiaque
US7704222B2 (en) 1998-09-10 2010-04-27 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US7815676B2 (en) 2006-07-07 2010-10-19 The Cleveland Clinic Foundation Apparatus and method for assisting in the removal of a cardiac valve
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US8062355B2 (en) 2005-11-04 2011-11-22 Jenavalve Technology, Inc. Self-expandable medical instrument for treating defects in a patient's heart
US8092520B2 (en) 2005-11-10 2012-01-10 CardiAQ Technologies, Inc. Vascular prosthesis connecting stent
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8206437B2 (en) 2001-08-03 2012-06-26 Philipp Bonhoeffer Implant implantation unit and procedure for implanting the unit
US8206438B2 (en) 2001-03-23 2012-06-26 Edwards Lifesciences Corporation Prosthetic heart valve having flared outflow section
EP2481375A2 (fr) * 2004-10-02 2012-08-01 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8337541B2 (en) 2008-10-01 2012-12-25 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8468667B2 (en) 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8679174B2 (en) 2005-01-20 2014-03-25 JenaValve Technology, GmbH Catheter for the transvascular implantation of prosthetic heart valves
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8728155B2 (en) 2011-03-21 2014-05-20 Cephea Valve Technologies, Inc. Disk-based valve apparatus and method for the treatment of valve dysfunction
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US8790395B2 (en) 2008-02-26 2014-07-29 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8894702B2 (en) 2008-09-29 2014-11-25 Cardiaq Valve Technologies, Inc. Replacement heart valve and method
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US8951299B2 (en) 2003-12-23 2015-02-10 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8956402B2 (en) 2001-06-29 2015-02-17 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9023100B2 (en) 2009-09-29 2015-05-05 Cardiaq Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US9333073B2 (en) 2009-04-15 2016-05-10 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery method
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US9339383B2 (en) 2001-10-11 2016-05-17 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US9393094B2 (en) 2005-09-13 2016-07-19 Boston Scientific Scimed, Inc. Two-part package for medical implant
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9439757B2 (en) 2014-12-09 2016-09-13 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US9480560B2 (en) 2009-09-29 2016-11-01 Edwards Lifesciences Cardiaq Llc Method of securing an intralumenal frame assembly
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9713529B2 (en) 2011-04-28 2017-07-25 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9724083B2 (en) 2013-07-26 2017-08-08 Edwards Lifesciences Cardiaq Llc Systems and methods for sealing openings in an anatomical wall
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9744031B2 (en) 2010-05-25 2017-08-29 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US9770329B2 (en) 2010-05-05 2017-09-26 Neovasc Tiara Inc. Transcatheter mitral valve prosthesis
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US20170325938A1 (en) 2016-05-16 2017-11-16 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US9839515B2 (en) 2005-12-22 2017-12-12 Symetis, SA Stent-valves for valve replacement and associated methods and systems for surgery
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9861476B2 (en) 2003-12-23 2018-01-09 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9867699B2 (en) 2008-02-26 2018-01-16 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US9918833B2 (en) 2010-09-01 2018-03-20 Medtronic Vascular Galway Prosthetic valve support structure
US9949831B2 (en) 2000-01-19 2018-04-24 Medtronics, Inc. Image-guided heart valve placement
US10016275B2 (en) 2012-05-30 2018-07-10 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US10022220B2 (en) 2000-04-06 2018-07-17 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10143552B2 (en) 2015-05-14 2018-12-04 Cephea Valve Technologies, Inc. Replacement mitral valves
US10172708B2 (en) 2012-01-25 2019-01-08 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10188516B2 (en) 2007-08-20 2019-01-29 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10201418B2 (en) 2010-09-10 2019-02-12 Symetis, SA Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10245136B2 (en) 2016-05-13 2019-04-02 Boston Scientific Scimed Inc. Containment vessel with implant sheathing guide
US10245142B2 (en) 2008-04-08 2019-04-02 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US10258465B2 (en) 2003-12-23 2019-04-16 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10278805B2 (en) 2000-08-18 2019-05-07 Atritech, Inc. Expandable implant devices for filtering blood flow from atrial appendages
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10314695B2 (en) 2003-12-23 2019-06-11 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
US10368990B2 (en) 2017-01-23 2019-08-06 Cephea Valve Technologies, Inc. Replacement mitral valves
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10449043B2 (en) 2015-01-16 2019-10-22 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US10470881B2 (en) 2015-05-14 2019-11-12 Cephea Valve Technologies, Inc. Replacement mitral valves
US10485976B2 (en) 1998-04-30 2019-11-26 Medtronic, Inc. Intracardiovascular access (ICVA™) system
US10555809B2 (en) 2012-06-19 2020-02-11 Boston Scientific Scimed, Inc. Replacement heart valve
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
US10709555B2 (en) 2015-05-01 2020-07-14 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10779940B2 (en) 2015-09-03 2020-09-22 Boston Scientific Scimed, Inc. Medical device handle
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10849746B2 (en) 2015-05-14 2020-12-01 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US10856970B2 (en) 2007-10-10 2020-12-08 Medtronic Ventor Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US11147668B2 (en) 2018-02-07 2021-10-19 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
US11191641B2 (en) 2018-01-19 2021-12-07 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11241310B2 (en) 2018-06-13 2022-02-08 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11246625B2 (en) 2018-01-19 2022-02-15 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US11285002B2 (en) 2003-12-23 2022-03-29 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US11304802B2 (en) 2006-09-19 2022-04-19 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US11331187B2 (en) 2016-06-17 2022-05-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
US11439732B2 (en) 2018-02-26 2022-09-13 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11504231B2 (en) 2018-05-23 2022-11-22 Corcym S.R.L. Cardiac valve prosthesis
US11771544B2 (en) 2011-05-05 2023-10-03 Symetis Sa Method and apparatus for compressing/loading stent-valves
US11969341B2 (en) 2022-11-18 2024-04-30 Corcym S.R.L. Cardiac valve prosthesis

Families Citing this family (427)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK124690D0 (da) 1990-05-18 1990-05-18 Henning Rud Andersen Klapprotes til implantering i kroppen for erstatning af naturlig klap samt kateter til brug ved implantering af en saadan klapprotese
EP0850607A1 (fr) 1996-12-31 1998-07-01 Cordis Corporation Prothèse de valve pour implantation dans des canaux corporels
FR2815844B1 (fr) 2000-10-31 2003-01-17 Jacques Seguin Support tubulaire de mise en place, par voie percutanee, d'une valve cardiaque de remplacement
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US6692513B2 (en) 2000-06-30 2004-02-17 Viacor, Inc. Intravascular filter with debris entrapment mechanism
US6602286B1 (en) 2000-10-26 2003-08-05 Ernst Peter Strecker Implantable valve system
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
FR2828091B1 (fr) 2001-07-31 2003-11-21 Seguin Jacques Ensemble permettant la mise en place d'une valve prothetique dans un conduit corporel
US8308797B2 (en) 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
US7007698B2 (en) 2002-04-03 2006-03-07 Boston Scientific Corporation Body lumen closure
US6752828B2 (en) 2002-04-03 2004-06-22 Scimed Life Systems, Inc. Artificial valve
AU2003223623A1 (en) 2002-06-19 2004-01-06 Tyco Healthcare Group, Lp Method and apparatus for anastomosis including annular joining member
AU2003285943B2 (en) 2002-10-24 2008-08-21 Boston Scientific Limited Venous valve apparatus and method
WO2004043273A2 (fr) * 2002-11-13 2004-05-27 Rosengart Todd K Appareil et procede permettant de couper une valve cardiaque
US6945957B2 (en) 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
CN2885311Y (zh) 2006-01-18 2007-04-04 郑成福 经尿道光动力疗法前列腺治疗仪
US20050128742A1 (en) * 2003-03-14 2005-06-16 Chen James C. Light generating device that self centers within a lumen to render photodynamic therapy
US20080269846A1 (en) * 2003-03-14 2008-10-30 Light Sciences Oncology, Inc. Device for treatment of blood vessels using light
WO2004082736A2 (fr) * 2003-03-14 2004-09-30 Light Sciences Corporation Dispositif de production de lumiere a usage intravasculaire
US10376711B2 (en) 2003-03-14 2019-08-13 Light Sciences Oncology Inc. Light generating guide wire for intravascular use
US7399315B2 (en) 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US7201772B2 (en) * 2003-07-08 2007-04-10 Ventor Technologies, Ltd. Fluid flow prosthetic device
BRPI0412362A (pt) * 2003-07-08 2006-09-05 Ventor Technologies Ltd dispositivos para implante protéticos particularmente para transporte transarterial no tratamento das estenoses aórticas e métodos para implantação para tais dispositivos
ATE548079T1 (de) * 2003-07-09 2012-03-15 Light Sciences Oncology Inc Vorrichtung zum distalen schutz und behandlung von blutgefässen
US20050075725A1 (en) 2003-10-02 2005-04-07 Rowe Stanton J. Implantable prosthetic valve with non-laminar flow
US20050075729A1 (en) * 2003-10-06 2005-04-07 Nguyen Tuoc Tan Minimally invasive valve replacement system
US7854761B2 (en) 2003-12-19 2010-12-21 Boston Scientific Scimed, Inc. Methods for venous valve replacement with a catheter
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US20060122693A1 (en) * 2004-05-10 2006-06-08 Youssef Biadillah Stent valve and method of manufacturing same
US20060122686A1 (en) * 2004-05-10 2006-06-08 Ran Gilad Stent and method of manufacturing same
US20060122692A1 (en) * 2004-05-10 2006-06-08 Ran Gilad Stent valve and method of using same
US7276078B2 (en) 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US20060052867A1 (en) 2004-09-07 2006-03-09 Medtronic, Inc Replacement prosthetic heart valve, system and method of implant
JP2008526319A (ja) * 2004-12-30 2008-07-24 ライト、サイエンシーズ、オンコロジー、インコーポレイテッド フレキシブルな光構造を使用する医療用器具およびその製造方法
US20060173490A1 (en) * 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7331991B2 (en) 2005-02-25 2008-02-19 California Institute Of Technology Implantable small percutaneous valve and methods of delivery
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US7780723B2 (en) 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
EP1945142B1 (fr) 2005-09-26 2013-12-25 Medtronic, Inc. Valve cardiaque prothétique et valvules veineuses
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US8778017B2 (en) 2005-10-26 2014-07-15 Cardiosolutions, Inc. Safety for mitral valve implant
US8092525B2 (en) 2005-10-26 2012-01-10 Cardiosolutions, Inc. Heart valve implant
US8216302B2 (en) 2005-10-26 2012-07-10 Cardiosolutions, Inc. Implant delivery and deployment system and method
US8852270B2 (en) 2007-11-15 2014-10-07 Cardiosolutions, Inc. Implant delivery system and method
US9259317B2 (en) 2008-06-13 2016-02-16 Cardiosolutions, Inc. System and method for implanting a heart implant
US8449606B2 (en) 2005-10-26 2013-05-28 Cardiosolutions, Inc. Balloon mitral spacer
US7785366B2 (en) 2005-10-26 2010-08-31 Maurer Christopher W Mitral spacer
US8764820B2 (en) 2005-11-16 2014-07-01 Edwards Lifesciences Corporation Transapical heart valve delivery system and method
US7799038B2 (en) 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US7780724B2 (en) * 2006-02-24 2010-08-24 California Institute Of Technology Monolithic in situ forming valve system
US20080275550A1 (en) * 2006-02-24 2008-11-06 Arash Kheradvar Implantable small percutaneous valve and methods of delivery
WO2008016578A2 (fr) 2006-07-31 2008-02-07 Cartledge Richard G Implants endovasculaires scellables et leurs procédés d'utilisation
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
EP2218425B1 (fr) 2006-09-08 2012-05-09 Edwards Lifesciences Corporation Système de mise en place de valvule cardiaque intégrée
US8685005B2 (en) * 2006-10-11 2014-04-01 Purdue Pharmaceutical Products L.P. Light delivery system
WO2008047354A2 (fr) 2006-10-16 2008-04-24 Ventor Technologies Ltd. Système d'administration transapicale avec dérivation de débordement ventriculo-artérielle
US8070799B2 (en) 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
EP1935378B1 (fr) 2006-12-19 2014-09-17 Sorin Group Italia S.r.l. Dispositif pour la mise en place d'une valve cardiaque
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
WO2008091493A1 (fr) 2007-01-08 2008-07-31 California Institute Of Technology Formation in situ d'une valvule
DE102007005900A1 (de) 2007-02-01 2008-08-07 Endosmart Gesellschaft für innovative Medizintechnik mbH Instrument zum operativen Entfernen einer defekten Herzklappe
US7967853B2 (en) 2007-02-05 2011-06-28 Boston Scientific Scimed, Inc. Percutaneous valve, system and method
US8663217B2 (en) * 2007-05-29 2014-03-04 Cvdevices, Llc Devices and systems for valve removal
US9504486B2 (en) 2010-04-19 2016-11-29 Cvdevices, Llc Devices, systems, and methods for valve removal
US20100168778A1 (en) * 2007-06-08 2010-07-01 Braido Peter N Devices for transcatheter prosthetic heart valve implantation and access closure
EP2420205B1 (fr) 2007-06-26 2014-04-09 St. Jude Medical, Inc. Appareil d'implantation des valvules cardiaques prothétiques démontables/extensibles
US8828079B2 (en) 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
EP3492043A3 (fr) 2007-08-21 2019-09-04 Symetis SA Valve de remplacement
AU2008294012B2 (en) 2007-08-24 2013-04-18 St. Jude Medical, Inc. Prosthetic aortic heart valves
US8808367B2 (en) 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US8114154B2 (en) * 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
DE102007043830A1 (de) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Herzklappenstent
EP3443938B1 (fr) 2007-09-26 2024-01-24 St. Jude Medical, LLC Valvules cardiaques prothétiques repliables
WO2009045334A1 (fr) 2007-09-28 2009-04-09 St. Jude Medical, Inc. Valvules cardiaques prothétiques repliables/déployables dotées de caractéristiques de retenue des valves natives calcifiées
US9532868B2 (en) 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
BRPI0819217B8 (pt) 2007-10-25 2021-06-22 Symetis Sa válvula de substituição para uso dentro de um corpo humano, sistema para substituir uma válvula dentro de um corpo humano e sistema de liberação da válvula cardíaca com stent
US8597347B2 (en) 2007-11-15 2013-12-03 Cardiosolutions, Inc. Heart regurgitation method and apparatus
DK2628464T3 (da) 2007-12-14 2020-03-09 Edwards Lifesciences Corp Proteseklap
US8876897B2 (en) * 2007-12-20 2014-11-04 Arash Kheradvar Implantable prosthetic valves and methods relating to same
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
CA3063001A1 (fr) 2008-02-29 2009-09-03 Edwards Lifesciences Corporation Element extensible servant a deployer une prothese
US8696689B2 (en) 2008-03-18 2014-04-15 Medtronic Ventor Technologies Ltd. Medical suturing device and method for use thereof
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US20090276040A1 (en) 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
LT3476367T (lt) 2008-06-06 2020-01-27 Edwards Lifesciences Corporation Mažo profilio transkateterinis širdies vožtuvas
US8591460B2 (en) * 2008-06-13 2013-11-26 Cardiosolutions, Inc. Steerable catheter and dilator and system and method for implanting a heart implant
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
EP2331016B8 (fr) * 2008-07-15 2020-06-03 St. Jude Medical, LLC Ancrage axial pliable et redéployable de valvule cardiaque prothétique pour divers états de maladie
ES2616743T3 (es) 2008-07-15 2017-06-14 St. Jude Medical, Llc Diseños de manguito colapsable y reexpansible de válvula cardiaca protésica y aplicaciones tecnológicas complementarias
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8790387B2 (en) 2008-10-10 2014-07-29 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
US8690936B2 (en) 2008-10-10 2014-04-08 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
WO2010067463A1 (fr) * 2008-12-10 2010-06-17 株式会社カルディオ Instrument pour capturer une pièce de tissu à utiliser dans la chirurgie de remplacement de valve aortique et procédé de capture d’une pièce de tissu dans la chirurgie de remplacement de valve aortique
US20100217382A1 (en) 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
BRPI1008902A2 (pt) 2009-02-27 2016-03-15 St Jude Medical válvula cardíaca protética.
US8353953B2 (en) 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
EP2250970B1 (fr) 2009-05-13 2012-12-26 Sorin Biomedica Cardio S.r.l. Dispositif pour interventions chirurgicales
US8403982B2 (en) 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US8439970B2 (en) 2009-07-14 2013-05-14 Edwards Lifesciences Corporation Transapical delivery system for heart valves
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
JP2011101782A (ja) * 2009-10-15 2011-05-26 Jms Co Ltd 心臓弁手術用補助具
AU2010311811B2 (en) 2009-11-02 2015-09-17 Symetis Sa Aortic bioprosthesis and systems for delivery thereof
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
EP3300695B1 (fr) 2009-12-08 2023-05-24 Avalon Medical Ltd. Dispositif et système de remplacement de valvule mitrale par transcathéter
US8518106B2 (en) 2010-02-17 2013-08-27 Medtronic, Inc. Catheter assembly with valve crimping accessories
US8475523B2 (en) 2010-02-17 2013-07-02 Medtronic, Inc. Distal tip assembly for a heart valve delivery catheter
US9414914B2 (en) 2010-02-24 2016-08-16 Medtronic Ventor Technologies Ltd. Catheter assembly with valve crimping accessories
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
DE102010011773B4 (de) * 2010-03-17 2015-10-01 Christian-Albrechts-Universität Zu Kiel Katheterbasierte Herzklappenablationsvorrichtung
CA2794750C (fr) 2010-03-26 2015-06-16 Thubrikar Aortic Valve, Inc. Composant valvulaire, composant de cadre et dispositif de prothese valvulaire les comprenant destine a etre implante dans une lumiere corporelle
EP3581151B1 (fr) 2010-04-21 2021-03-10 Medtronic, Inc. Valvule prothétique à membres scellables
US9387077B2 (en) 2010-05-27 2016-07-12 Medtronic Vascular Galway Catheter assembly with prosthesis crimping and prosthesis retaining accessories
US9795476B2 (en) 2010-06-17 2017-10-24 St. Jude Medical, Llc Collapsible heart valve with angled frame
CN103153384B (zh) 2010-06-28 2016-03-09 科利柏心脏瓣膜有限责任公司 用于经腔输送血管内器件的装置
DK2590595T3 (en) 2010-07-09 2015-12-07 Highlife Sas Transcatheter atrioventricular heart valve prosthesis
EP4098227A1 (fr) 2010-07-23 2022-12-07 Edwards Lifesciences Corporation Mécanismes de retenue pour valvules prothétiques
US9039759B2 (en) 2010-08-24 2015-05-26 St. Jude Medical, Cardiology Division, Inc. Repositioning of prosthetic heart valve and deployment
BR112013004264A2 (pt) 2010-08-24 2016-08-02 St Jude Medical dispositivo, sistema e método de colocação para uma válvula cardíaca protética colapsável
BR112013006295A2 (pt) 2010-09-17 2016-06-07 St Jude Medical Cardiology Div dispositivo para flexionar uma válvula cardíaca protética autoexpansível, e, método para carregar uma válvula cardíaca protética autoexpansível
EP2616007B1 (fr) 2010-09-17 2020-06-03 St. Jude Medical, Cardiology Division, Inc. Dispositifs de déploiement échelonné pour l'acheminement de valves cardiaques à travers des sondes
USD660967S1 (en) 2010-09-20 2012-05-29 St. Jude Medical, Inc. Surgical stent
USD652926S1 (en) 2010-09-20 2012-01-24 St. Jude Medical, Inc. Forked end
USD653343S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Surgical cuff
USD660432S1 (en) 2010-09-20 2012-05-22 St. Jude Medical, Inc. Commissure point
EP2618781B1 (fr) 2010-09-20 2023-02-01 St. Jude Medical, Cardiology Division, Inc. Fixation de feuillet de valve dans des valves prothétiques rétractables
USD652927S1 (en) 2010-09-20 2012-01-24 St. Jude Medical, Inc. Surgical stent
USD653342S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Stent connections
USD654169S1 (en) 2010-09-20 2012-02-14 St. Jude Medical Inc. Forked ends
USD648854S1 (en) 2010-09-20 2011-11-15 St. Jude Medical, Inc. Commissure points
USD684692S1 (en) 2010-09-20 2013-06-18 St. Jude Medical, Inc. Forked ends
USD660433S1 (en) 2010-09-20 2012-05-22 St. Jude Medical, Inc. Surgical stent assembly
USD654170S1 (en) 2010-09-20 2012-02-14 St. Jude Medical, Inc. Stent connections
USD653341S1 (en) 2010-09-20 2012-01-31 St. Jude Medical, Inc. Surgical stent
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
ES2834106T3 (es) 2010-10-05 2021-06-16 Edwards Lifesciences Corp Válvula cardiaca protésica
US20120116496A1 (en) 2010-11-05 2012-05-10 Chuter Timothy A Stent structures for use with valve replacements
GB201019354D0 (en) 2010-11-16 2010-12-29 Vascutek Ltd Prothesis
CA2820738C (fr) 2010-12-14 2019-01-15 Colibri Heart Valve Llc Valvule cardiaque apte a etre posee par voie percutanee, comprenant des valves a membranes repliees a feuillets integres
US9717593B2 (en) 2011-02-01 2017-08-01 St. Jude Medical, Cardiology Division, Inc. Leaflet suturing to commissure points for prosthetic heart valve
US8932343B2 (en) 2011-02-01 2015-01-13 St. Jude Medical, Cardiology Division, Inc. Blunt ended stent for prosthetic heart valve
EP3501456A1 (fr) 2011-02-02 2019-06-26 St. Jude Medical, LLC Système de chargement d'une valvule cardiaque pliable
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9381082B2 (en) 2011-04-22 2016-07-05 Edwards Lifesciences Corporation Devices, systems and methods for accurate positioning of a prosthetic valve
US20120303048A1 (en) 2011-05-24 2012-11-29 Sorin Biomedica Cardio S.R.I. Transapical valve replacement
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US8893370B2 (en) 2011-07-28 2014-11-25 St. Jude Medical, Cardiology Division, Inc. System for loading a collapsible heart valve
AU2012286789B2 (en) 2011-07-28 2016-10-27 St. Jude Medical, Cardiology Division, Inc. System for loading a collapsible heart valve
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
EP2741711B1 (fr) 2011-08-11 2018-05-30 Tendyne Holdings, Inc. Améliorations apportées à des valves prothétiques et inventions associées
US9060860B2 (en) 2011-08-18 2015-06-23 St. Jude Medical, Cardiology Division, Inc. Devices and methods for transcatheter heart valve delivery
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
CA3097364C (fr) 2011-12-09 2023-08-01 Edwards Lifesciences Corporation Valvule prothetique ayant des supports de commissure ameliores
US8652145B2 (en) 2011-12-14 2014-02-18 Edwards Lifesciences Corporation System and method for crimping a prosthetic valve
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US20130158654A1 (en) * 2011-12-20 2013-06-20 Boston Scientific Scimed, Inc. Heart valve replacement catheter
EP3281608B1 (fr) 2012-02-10 2020-09-16 CVDevices, LLC Mediyinprodukt mit rahmen und viszeralen pleura
CA2865013C (fr) 2012-02-22 2020-12-15 Syntheon Cardiology, Llc Endoprothese a commande active, greffe d'endoprothese, valve cardiaque et methode de commande de celles-ci
EP2825107B1 (fr) * 2012-03-14 2017-07-19 Université Catholique de Louvain Dispositif pour l'excision de valvule cardiaque par voie mini-invasive
US11207176B2 (en) 2012-03-22 2021-12-28 Boston Scientific Scimed, Inc. Transcatheter stent-valves and methods, systems and devices for addressing para-valve leakage
US20130274873A1 (en) 2012-03-22 2013-10-17 Symetis Sa Transcatheter Stent-Valves and Methods, Systems and Devices for Addressing Para-Valve Leakage
ES2675936T3 (es) 2012-03-23 2018-07-13 Sorin Group Italia S.R.L. Prótesis de válvula plegable
US9427315B2 (en) 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
US9532871B2 (en) 2012-05-04 2017-01-03 St. Jude Medical, Cardiology Division, Inc. Delivery system deflection mechanism
US9277990B2 (en) 2012-05-04 2016-03-08 St. Jude Medical, Cardiology Division, Inc. Hypotube shaft with articulation mechanism
US9554902B2 (en) 2012-06-28 2017-01-31 St. Jude Medical, Cardiology Division, Inc. Leaflet in configuration for function in various shapes and sizes
US9289292B2 (en) 2012-06-28 2016-03-22 St. Jude Medical, Cardiology Division, Inc. Valve cuff support
US9615920B2 (en) 2012-06-29 2017-04-11 St. Jude Medical, Cardiology Divisions, Inc. Commissure attachment feature for prosthetic heart valve
US20140005776A1 (en) 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
US9241791B2 (en) 2012-06-29 2016-01-26 St. Jude Medical, Cardiology Division, Inc. Valve assembly for crimp profile
US9808342B2 (en) 2012-07-03 2017-11-07 St. Jude Medical, Cardiology Division, Inc. Balloon sizing device and method of positioning a prosthetic heart valve
US10004597B2 (en) 2012-07-03 2018-06-26 St. Jude Medical, Cardiology Division, Inc. Stent and implantable valve incorporating same
WO2014022124A1 (fr) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Conceptions multi-composantes améliorées pour dispositif de récupération de valve cardiaque, structures d'étanchéité et ensemble stent
WO2014021905A1 (fr) 2012-07-30 2014-02-06 Tendyne Holdings, Inc. Systèmes et procédés d'administration améliorée pour valvules prothétiques transcathéter
EP2695586B1 (fr) 2012-08-10 2019-05-08 Sorin Group Italia S.r.l. Prothèse de valvule et kit
US9707076B2 (en) 2012-08-23 2017-07-18 Minimally Invasive Surgical Access Limited Direct aortic access system for transcatheter aortic valve procedures
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
DE102012109459A1 (de) 2012-10-04 2014-04-10 Aesculap Ag Weiteneinstellbares Schneidinstrument zur transapikalen Aortenklappenresektion
US10524909B2 (en) 2012-10-12 2020-01-07 St. Jude Medical, Cardiology Division, Inc. Retaining cage to permit resheathing of a tavi aortic-first transapical system
US9295549B2 (en) 2012-10-12 2016-03-29 St. Jude Medical, Cardiology Division, Inc. Valve holder and loading integration
US9801721B2 (en) 2012-10-12 2017-10-31 St. Jude Medical, Cardiology Division, Inc. Sizing device and method of positioning a prosthetic heart valve
EP2922592B1 (fr) 2012-11-21 2022-09-21 Edwards Lifesciences Corporation Mécanismes de retenue pour valvules cardiaques prothétiques
US9314163B2 (en) 2013-01-29 2016-04-19 St. Jude Medical, Cardiology Division, Inc. Tissue sensing device for sutureless valve selection
US9387073B2 (en) 2013-01-29 2016-07-12 St. Jude Medical, Cardiology Division, Inc. Delivery device distal sheath connector
US9655719B2 (en) 2013-01-29 2017-05-23 St. Jude Medical, Cardiology Division, Inc. Surgical heart valve flexible stent frame stiffener
US9186238B2 (en) 2013-01-29 2015-11-17 St. Jude Medical, Cardiology Division, Inc. Aortic great vessel protection
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
CA2900862C (fr) 2013-02-11 2017-10-03 Cook Medical Technologies Llc Cadre de support extensible et dispositif medical
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
WO2014130160A1 (fr) 2013-02-21 2014-08-28 St. Jude Medical, Cardiology Division, Inc. Conception de système de mise en place d'articulation passive transapicale
US9901470B2 (en) 2013-03-01 2018-02-27 St. Jude Medical, Cardiology Division, Inc. Methods of repositioning a transcatheter heart valve after full deployment
US9844435B2 (en) 2013-03-01 2017-12-19 St. Jude Medical, Cardiology Division, Inc. Transapical mitral valve replacement
US9119713B2 (en) 2013-03-11 2015-09-01 St. Jude Medical, Cardiology Division, Inc. Transcatheter valve replacement
US10271949B2 (en) 2013-03-12 2019-04-30 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak occlusion device for self-expanding heart valves
US9398951B2 (en) 2013-03-12 2016-07-26 St. Jude Medical, Cardiology Division, Inc. Self-actuating sealing portions for paravalvular leak protection
US9339274B2 (en) 2013-03-12 2016-05-17 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak occlusion device for self-expanding heart valves
US10314698B2 (en) 2013-03-12 2019-06-11 St. Jude Medical, Cardiology Division, Inc. Thermally-activated biocompatible foam occlusion device for self-expanding heart valves
US9636222B2 (en) 2013-03-12 2017-05-02 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak protection
US9867697B2 (en) 2013-03-12 2018-01-16 St. Jude Medical, Cardiology Division, Inc. Self-actuating sealing portions for a paravalvular leak protection
US9131982B2 (en) 2013-03-14 2015-09-15 St. Jude Medical, Cardiology Division, Inc. Mediguide-enabled renal denervation system for ensuring wall contact and mapping lesion locations
US9326856B2 (en) 2013-03-14 2016-05-03 St. Jude Medical, Cardiology Division, Inc. Cuff configurations for prosthetic heart valve
US9744037B2 (en) 2013-03-15 2017-08-29 California Institute Of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US9232998B2 (en) 2013-03-15 2016-01-12 Cardiosolutions Inc. Trans-apical implant systems, implants and methods
US9289297B2 (en) 2013-03-15 2016-03-22 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
US10149757B2 (en) 2013-03-15 2018-12-11 Edwards Lifesciences Corporation System and method for transaortic delivery of a prosthetic heart valve
US11224510B2 (en) 2013-04-02 2022-01-18 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US10463489B2 (en) 2013-04-02 2019-11-05 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US10478293B2 (en) 2013-04-04 2019-11-19 Tendyne Holdings, Inc. Retrieval and repositioning system for prosthetic heart valve
CA3134578C (fr) 2013-05-20 2024-01-02 Edwards Lifesciences Corporation Appareil de pose de valvule cardiaque prothetique
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
AU2014277902A1 (en) 2013-06-14 2016-02-04 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
EP3010431B1 (fr) 2013-06-18 2019-10-30 St. Jude Medical, Cardiology Division, Inc. Introducteur transapical
WO2014204807A1 (fr) 2013-06-19 2014-12-24 Aga Medical Corporation Valvule repliable pourvue d'une protection contre les fuites paravalvulaires
CA2914856C (fr) 2013-06-25 2021-03-09 Chad Perrin Caracteristiques de gestion de thrombus et de conformite structurelle pour valvules cardiaques prothetiques
CA2919379C (fr) 2013-08-01 2021-03-30 Tendyne Holdings, Inc. Dispositifs et procedes d'ancrage epicardique
EP2835112B1 (fr) 2013-08-08 2021-01-27 Sorin Group Italia S.r.l. Prothèse de valvule cardiaque
BR112016002887B1 (pt) 2013-08-12 2021-05-25 Mitral Valve Technologies Sarl sistema para substituição de uma válvula cardíaca nativa
JP6328242B2 (ja) 2013-08-14 2018-05-23 マイトラル・ヴァルヴ・テクノロジーズ・エス・アー・エール・エル 心臓弁置換のためのシステム
USD730521S1 (en) 2013-09-04 2015-05-26 St. Jude Medical, Cardiology Division, Inc. Stent with commissure attachments
USD730520S1 (en) 2013-09-04 2015-05-26 St. Jude Medical, Cardiology Division, Inc. Stent with commissure attachments
US9867611B2 (en) 2013-09-05 2018-01-16 St. Jude Medical, Cardiology Division, Inc. Anchoring studs for transcatheter valve implantation
WO2015038615A1 (fr) 2013-09-12 2015-03-19 St. Jude Medical, Cardiology Division, Inc. Interface atraumatique dans un dispositif d'administration d'implant
US10123870B2 (en) 2013-09-12 2018-11-13 St. Jude Medical, Cardiology Division, Inc. Alignment of an implantable medical device
WO2015038458A1 (fr) 2013-09-12 2015-03-19 St. Jude Medical, Cardiology Division, Inc. Modèles d'endoprothèse vasculaire pour valvules cardiaques prothétiques
WO2015058039A1 (fr) 2013-10-17 2015-04-23 Robert Vidlund Appareil et procedes d'alignement et de deploiement de dispositifs intracardiaques
US9421094B2 (en) 2013-10-23 2016-08-23 Caisson Interventional, LLC Methods and systems for heart valve therapy
CN108403261B (zh) 2013-10-28 2021-02-12 坦迪尼控股股份有限公司 假体心脏瓣膜以及用于输送假体心脏瓣膜的系统和方法
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
EP2870946B1 (fr) 2013-11-06 2018-10-31 St. Jude Medical, Cardiology Division, Inc. Mécanisme d'étanchéité de fuite paravalvulaire
US9700409B2 (en) 2013-11-06 2017-07-11 St. Jude Medical, Cardiology Division, Inc. Reduced profile prosthetic heart valve
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
CN106456320B (zh) 2013-11-11 2020-01-21 爱德华兹生命科学卡迪尔克有限责任公司 用于制造支架框架的系统和方法
EP3068344A1 (fr) 2013-11-12 2016-09-21 St. Jude Medical, Cardiology Division, Inc. Système de pose pneumatique de valvule aortique transcathéter
WO2015077274A1 (fr) 2013-11-19 2015-05-28 St. Jude Medical, Cardiology Division, Inc. Structures d'étanchéité servant de protection contre les fuites paravalvulaires
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
EP3073964A1 (fr) 2013-11-27 2016-10-05 St. Jude Medical, Cardiology Division, Inc. Piqûres de renfort de ballonnet
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9901444B2 (en) 2013-12-17 2018-02-27 Edwards Lifesciences Corporation Inverted valve structure
EP3082655B1 (fr) 2013-12-19 2020-01-15 St. Jude Medical, Cardiology Division, Inc. Fixations feuillet-manchon pour valve cardiaque prothétique
US9943408B2 (en) 2014-01-08 2018-04-17 St. Jude Medical, Cardiology Division, Inc. Basket delivery system
US9820852B2 (en) 2014-01-24 2017-11-21 St. Jude Medical, Cardiology Division, Inc. Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs
US20150209141A1 (en) 2014-01-24 2015-07-30 St. Jude Medical, Cardiology Division, Inc. Stationary intra-annular halo designs for paravalvular leak (pvl) reduction-passive channel filling cuff designs
WO2015120122A2 (fr) 2014-02-05 2015-08-13 Robert Vidlund Appareil et procédés pour la mise en place d'une valve mitrale prothétique par l'artère fémorale
US10292711B2 (en) 2014-02-07 2019-05-21 St. Jude Medical, Cardiology Division, Inc. Mitral valve treatment device having left atrial appendage closure
EP2904967A1 (fr) 2014-02-07 2015-08-12 St. Jude Medical, Cardiology Division, Inc. Système et procédé d'évaluation de dimensions et de l'excentricité d'un anneau de valve pour implantation de valvule trans-cathéter
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
CA3153863C (fr) 2014-02-18 2023-08-29 Edwards Lifesciences Corporation Cadre a commissure flexible
SG11201606836TA (en) 2014-02-20 2016-09-29 Mitral Valve Technologies Sarl Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device
EP3782585B1 (fr) 2014-02-21 2023-06-28 Mitral Valve Technologies Sàrl Valvule mitrale prothétique et dispositif d'ancrage
CN110338911B (zh) 2014-03-10 2022-12-23 坦迪尼控股股份有限公司 用于定位和监测假体二尖瓣的系绳负荷的装置和方法
US9763778B2 (en) 2014-03-18 2017-09-19 St. Jude Medical, Cardiology Division, Inc. Aortic insufficiency valve percutaneous valve anchoring
CR20160398A (es) 2014-03-18 2016-11-10 St Jude Medical Cardiology Div Inc Fijador/sujetador de celda basculante/ alterna para reemplazo de válvula mitral
EP3119352B1 (fr) 2014-03-21 2023-12-20 St. Jude Medical, Cardiology Division, Inc. Atténuation de l'abrasion d'une lame valvulaire
WO2015148241A1 (fr) 2014-03-26 2015-10-01 St. Jude Medical, Cardiology Division, Inc. Cadres transcathéter d'endoprothèse de valvule mitrale
EP3125826B1 (fr) 2014-03-31 2020-10-07 St. Jude Medical, Cardiology Division, Inc. Étanchéité paravalvulaire via des mécanismes de manchon étendu
US10226332B2 (en) 2014-04-14 2019-03-12 St. Jude Medical, Cardiology Division, Inc. Leaflet abrasion mitigation in prosthetic heart valves
US10154904B2 (en) 2014-04-28 2018-12-18 Edwards Lifesciences Corporation Intravascular introducer devices
US10195025B2 (en) 2014-05-12 2019-02-05 Edwards Lifesciences Corporation Prosthetic heart valve
EP3142603B1 (fr) 2014-05-14 2018-03-07 Sorin Group Italia S.r.l. Dispositif d'implant et kit d'implantation
WO2015175524A1 (fr) 2014-05-16 2015-11-19 St. Jude Medical, Cardiology Division, Inc. Étanchéité annulaire secondaire pour protection contre des fuites paravalvulaires
EP3257473A1 (fr) 2014-05-16 2017-12-20 St. Jude Medical, Cardiology Division, Inc. Ensemble de stent destiné à être utilisé dans des valvules cardiaques prothétiques
EP3142604B1 (fr) 2014-05-16 2024-01-10 St. Jude Medical, Cardiology Division, Inc. Valve transcathéter avec anneau d'étanchéité de fuite paravalvulaire
US10500042B2 (en) 2014-05-22 2019-12-10 St. Jude Medical, Cardiology Division, Inc. Stents with anchoring sections
US9687345B2 (en) 2014-05-29 2017-06-27 Edwards Lifesciences Cardiaq Llc Prosthesis, delivery device and methods of use
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
EP2954875B1 (fr) 2014-06-10 2017-11-15 St. Jude Medical, Cardiology Division, Inc. Pont de cellule de stent pour fixation de manchon
US9974647B2 (en) 2014-06-12 2018-05-22 Caisson Interventional, LLC Two stage anchor and mitral valve assembly
US10195026B2 (en) 2014-07-22 2019-02-05 Edwards Lifesciences Corporation Mitral valve anchoring
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
US10016272B2 (en) 2014-09-12 2018-07-10 Mitral Valve Technologies Sarl Mitral repair and replacement devices and methods
EP3009104B1 (fr) 2014-10-14 2019-11-20 St. Jude Medical, Cardiology Division, Inc. Cathéter flexible et procédés de formation associés
US9750605B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750607B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US20160144156A1 (en) 2014-11-20 2016-05-26 Edwards Lifesciences Corporation Inflatable device with etched modifications
CR20170245A (es) 2014-12-05 2017-09-14 Edwards Lifesciences Corp Cateter dirigible con cable de tracción
CA2972966C (fr) 2015-01-07 2023-01-10 Tendyne Holdings, Inc. Protheses de valvules mitrales et appareil et procedes de mise en place associe
EP3253331B1 (fr) 2015-02-05 2021-04-07 Tendyne Holdings, Inc. Valvule cardiac prothétique avec câble d'attache et tampon épicardique expansible
US10231834B2 (en) 2015-02-09 2019-03-19 Edwards Lifesciences Corporation Low profile transseptal catheter and implant system for minimally invasive valve procedure
US10039637B2 (en) 2015-02-11 2018-08-07 Edwards Lifesciences Corporation Heart valve docking devices and implanting methods
US10314699B2 (en) 2015-03-13 2019-06-11 St. Jude Medical, Cardiology Division, Inc. Recapturable valve-graft combination and related methods
WO2016154172A2 (fr) 2015-03-24 2016-09-29 St. Jude Medical, Cardiology Division, Inc. Remplacement de valvule mitrale
EP3273911A1 (fr) 2015-03-24 2018-01-31 St. Jude Medical, Cardiology Division, Inc. Valvule mitrale prothétique
US10716672B2 (en) 2015-04-07 2020-07-21 St. Jude Medical, Cardiology Division, Inc. System and method for intraprocedural assessment of geometry and compliance of valve annulus for trans-catheter valve implantation
US10327896B2 (en) 2015-04-10 2019-06-25 Edwards Lifesciences Corporation Expandable sheath with elastomeric cross sectional portions
US10792471B2 (en) 2015-04-10 2020-10-06 Edwards Lifesciences Corporation Expandable sheath
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
EP3695810B1 (fr) 2015-04-16 2022-05-18 Tendyne Holdings, Inc. Appareils pour la récupération des valves prothétiques transcathéter
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10232564B2 (en) 2015-04-29 2019-03-19 Edwards Lifesciences Corporation Laminated sealing member for prosthetic heart valve
WO2016201024A1 (fr) 2015-06-12 2016-12-15 St. Jude Medical, Cardiology Division, Inc. Réparation et remplacement de valvule cardiaque
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
WO2017011199A1 (fr) 2015-07-16 2017-01-19 St. Jude Medical, Cardiology Division, Inc. Valvule cardiaque prothétique sans suture
US10179046B2 (en) 2015-08-14 2019-01-15 Edwards Lifesciences Corporation Gripping and pushing device for medical instrument
US11026788B2 (en) 2015-08-20 2021-06-08 Edwards Lifesciences Corporation Loader and retriever for transcatheter heart valve, and methods of crimping transcatheter heart valve
WO2017040774A1 (fr) 2015-09-03 2017-03-09 St. Jude Medical, Cardiology Division, Inc. Gaine d'introducteur présentant des parties extensibles
US10588744B2 (en) 2015-09-04 2020-03-17 Edwards Lifesciences Corporation Delivery system for prosthetic heart valve
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US10314703B2 (en) 2015-09-21 2019-06-11 Edwards Lifesciences Corporation Cylindrical implant and balloon
US10350067B2 (en) 2015-10-26 2019-07-16 Edwards Lifesciences Corporation Implant delivery capsule
US11259920B2 (en) 2015-11-03 2022-03-01 Edwards Lifesciences Corporation Adapter for prosthesis delivery device and methods of use
US10376364B2 (en) 2015-11-10 2019-08-13 Edwards Lifesciences Corporation Implant delivery capsule
US10470876B2 (en) 2015-11-10 2019-11-12 Edwards Lifesciences Corporation Transcatheter heart valve for replacing natural mitral valve
US10321996B2 (en) 2015-11-11 2019-06-18 Edwards Lifesciences Corporation Prosthetic valve delivery apparatus having clutch mechanism
US11033387B2 (en) 2015-11-23 2021-06-15 Edwards Lifesciences Corporation Methods for controlled heart valve delivery
US10265169B2 (en) 2015-11-23 2019-04-23 Edwards Lifesciences Corporation Apparatus for controlled heart valve delivery
US10583007B2 (en) 2015-12-02 2020-03-10 Edwards Lifesciences Corporation Suture deployment of prosthetic heart valve
CA3005908A1 (fr) 2015-12-03 2017-06-08 Tendyne Holdings, Inc. Attributs de cadre pour valvules mitrales prothetiques
US10357351B2 (en) 2015-12-04 2019-07-23 Edwards Lifesciences Corporation Storage assembly for prosthetic valve
EP3397206B1 (fr) 2015-12-28 2022-06-08 Tendyne Holdings, Inc. Fermetures de poche auriculaire pour valvules cardiaques prothétiques
US10265166B2 (en) 2015-12-30 2019-04-23 Caisson Interventional, LLC Systems and methods for heart valve therapy
DE202017007326U1 (de) 2016-01-29 2020-10-20 Neovasc Tiara Inc. Klappenprothese zum Verhindern einer Abflussobstruktion
US10179043B2 (en) 2016-02-12 2019-01-15 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
US10779941B2 (en) 2016-03-08 2020-09-22 Edwards Lifesciences Corporation Delivery cylinder for prosthetic implant
US11219746B2 (en) 2016-03-21 2022-01-11 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10799676B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10799677B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
SG10202108804RA (en) 2016-03-24 2021-09-29 Edwards Lifesciences Corp Delivery system for prosthetic heart valve
US10470877B2 (en) 2016-05-03 2019-11-12 Tendyne Holdings, Inc. Apparatus and methods for anterior valve leaflet management
EP3454785B1 (fr) 2016-05-13 2021-11-17 St. Jude Medical, Cardiology Division, Inc. Valvule cardiaque à stent ayant des densités cellulaires variables
WO2017218375A1 (fr) 2016-06-13 2017-12-21 Tendyne Holdings, Inc. Administration séquentielle de valvule mitrale prothétique en deux parties
JP6968113B2 (ja) 2016-06-30 2021-11-17 テンダイン ホールディングス，インコーポレイテッド 人工心臓弁の経心尖送達装置
US10856981B2 (en) 2016-07-08 2020-12-08 Edwards Lifesciences Corporation Expandable sheath and methods of using the same
US11065116B2 (en) 2016-07-12 2021-07-20 Tendyne Holdings, Inc. Apparatus and methods for trans-septal retrieval of prosthetic heart valves
US11096781B2 (en) 2016-08-01 2021-08-24 Edwards Lifesciences Corporation Prosthetic heart valve
WO2018039543A1 (fr) 2016-08-26 2018-03-01 St. Jude Medical, Cardiology Division, Inc. Valve cardiaque prothétique à caractéristiques de limitation des fuites para-valvulaires
US10357361B2 (en) 2016-09-15 2019-07-23 Edwards Lifesciences Corporation Heart valve pinch devices and delivery systems
EP3512466B1 (fr) 2016-09-15 2020-07-29 St. Jude Medical, Cardiology Division, Inc. Valvule cardiaque prothétique dont la caractéristique est la limitation de fuites paravalvulaires
US10575944B2 (en) 2016-09-22 2020-03-03 Edwards Lifesciences Corporation Prosthetic heart valve with reduced stitching
WO2018081490A1 (fr) 2016-10-28 2018-05-03 St. Jude Medical, Cardiology Division, Inc. Valvule mitrale prothétique
US10973631B2 (en) 2016-11-17 2021-04-13 Edwards Lifesciences Corporation Crimping accessory device for a prosthetic valve
US10463484B2 (en) 2016-11-17 2019-11-05 Edwards Lifesciences Corporation Prosthetic heart valve having leaflet inflow below frame
EP3541462A4 (fr) 2016-11-21 2020-06-17 Neovasc Tiara Inc. Procédés et systèmes de rétraction rapide d'un système de pose de valvule cardiaque transcathéter
EP3547965A1 (fr) 2016-12-02 2019-10-09 St. Jude Medical, Cardiology Division, Inc. Système de pose par transcathéter avec deux modes d'actionnement
WO2018102520A1 (fr) 2016-12-02 2018-06-07 St. Jude Medical, Cardiology Division, Inc. Système de pose par transcathéter à actionnement de roue transversale
US10603165B2 (en) 2016-12-06 2020-03-31 Edwards Lifesciences Corporation Mechanically expanding heart valve and delivery apparatus therefor
PL3554424T3 (pl) 2016-12-16 2023-05-08 Edwards Lifesciences Corporation Systemy i narzędzia służące do rozkładania do doprowadzania urządzenia kotwiącego dla zastawki protetycznej
EP3558165B1 (fr) 2016-12-20 2021-04-28 Edwards Lifesciences Corporation Systèmes et mécanismes pour déployer un dispositif d'amarrage pour une valvule cardiaque de remplacement
US11654023B2 (en) 2017-01-23 2023-05-23 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11185406B2 (en) 2017-01-23 2021-11-30 Edwards Lifesciences Corporation Covered prosthetic heart valve
WO2018160790A1 (fr) 2017-03-03 2018-09-07 St. Jude Medical, Cardiology Division, Inc. Conception de valve mitrale transcathéter
US10842624B2 (en) 2017-03-10 2020-11-24 St. Jude Medical, Cardiology Division, Inc. Transseptal mitral valve delivery system
US10660752B2 (en) 2017-03-16 2020-05-26 St. Jude Medical, Cardiology Division, Inc. Retainers for transcatheter heart valve delivery systems
DK3682854T3 (da) 2017-04-18 2022-02-14 Edwards Lifesciences Corp Hjerteklaptætningsindretninger og tilførselsindretninger dertil
US11224511B2 (en) 2017-04-18 2022-01-18 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
US10973634B2 (en) 2017-04-26 2021-04-13 Edwards Lifesciences Corporation Delivery apparatus for a prosthetic heart valve
WO2018204736A1 (fr) 2017-05-05 2018-11-08 St. Jude Medical, Cardiology Division, Inc. Gaine d'introducteur présentant des parties extensibles
US10959846B2 (en) 2017-05-10 2021-03-30 Edwards Lifesciences Corporation Mitral valve spacer device
US10842619B2 (en) 2017-05-12 2020-11-24 Edwards Lifesciences Corporation Prosthetic heart valve docking assembly
USD875250S1 (en) 2017-05-15 2020-02-11 St. Jude Medical, Cardiology Division, Inc. Stent having tapered aortic struts
USD875935S1 (en) 2017-05-15 2020-02-18 St. Jude Medical, Cardiology Division, Inc. Stent having tapered struts
US10898324B2 (en) 2017-05-15 2021-01-26 St. Jude Medical, Cardiology Division, Inc. Transcatheter delivery system with wheel actuation
USD889653S1 (en) 2017-05-15 2020-07-07 St. Jude Medical, Cardiology Division, Inc. Stent having tapered struts
US11135056B2 (en) 2017-05-15 2021-10-05 Edwards Lifesciences Corporation Devices and methods of commissure formation for prosthetic heart valve
EP3630013B1 (fr) 2017-05-22 2024-04-24 Edwards Lifesciences Corporation Dispositif d'ancrage de valvule
US20210401571A9 (en) 2017-05-31 2021-12-30 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10869759B2 (en) 2017-06-05 2020-12-22 Edwards Lifesciences Corporation Mechanically expandable heart valve
US11026785B2 (en) 2017-06-05 2021-06-08 Edwards Lifesciences Corporation Mechanically expandable heart valve
US10639152B2 (en) 2017-06-21 2020-05-05 Edwards Lifesciences Corporation Expandable sheath and methods of using the same
CN110996853B (zh) 2017-06-30 2023-01-10 爱德华兹生命科学公司 经导管瓣膜的对接站
WO2019006332A1 (fr) 2017-06-30 2019-01-03 Edwards Lifesciences Corporation Mécanismes de verrouillage et de déverrouillage pour dispositifs implantables trans-cathéters
US10857334B2 (en) 2017-07-12 2020-12-08 Edwards Lifesciences Corporation Reduced operation force inflator
JP7216066B2 (ja) 2017-07-13 2023-01-31 テンダイン ホールディングス，インコーポレイテッド 人工心臓弁とその送達のための装置および方法
WO2019018319A1 (fr) 2017-07-18 2019-01-24 St. Jude Medical, Cardiology Division, Inc. Base de chargement jetable dans les toilettes
US10918473B2 (en) 2017-07-18 2021-02-16 Edwards Lifesciences Corporation Transcatheter heart valve storage container and crimping mechanism
ES2959773T3 (es) 2017-08-11 2024-02-28 Edwards Lifesciences Corp Elemento de sellado para válvula cardiaca protésica
US11083575B2 (en) 2017-08-14 2021-08-10 Edwards Lifesciences Corporation Heart valve frame design with non-uniform struts
US10932903B2 (en) 2017-08-15 2021-03-02 Edwards Lifesciences Corporation Skirt assembly for implantable prosthetic valve
US10898319B2 (en) 2017-08-17 2021-01-26 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10973628B2 (en) 2017-08-18 2021-04-13 Edwards Lifesciences Corporation Pericardial sealing member for prosthetic heart valve
US10722353B2 (en) 2017-08-21 2020-07-28 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10806573B2 (en) 2017-08-22 2020-10-20 Edwards Lifesciences Corporation Gear drive mechanism for heart valve delivery apparatus
WO2019036810A1 (fr) 2017-08-25 2019-02-28 Neovasc Tiara Inc. Prothèse de valvule mitrale transcathéter à déploiement séquentiel
JP7291124B2 (ja) 2017-08-28 2023-06-14 テンダイン ホールディングス，インコーポレイテッド テザー連結部を有する人工心臓弁
US11051939B2 (en) 2017-08-31 2021-07-06 Edwards Lifesciences Corporation Active introducer sheath system
US10973629B2 (en) 2017-09-06 2021-04-13 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US11147667B2 (en) 2017-09-08 2021-10-19 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
WO2019051476A1 (fr) 2017-09-11 2019-03-14 Incubar, LLC Dispositif d'étanchéité destiné à être utilisé comme implant vasculaire de conduit pour réduire l'endofuite
IL273562B2 (en) 2017-10-18 2024-01-01 Edwards Lifesciences Corp Catheter assembly
US11207499B2 (en) 2017-10-20 2021-12-28 Edwards Lifesciences Corporation Steerable catheter
US11382751B2 (en) 2017-10-24 2022-07-12 St. Jude Medical, Cardiology Division, Inc. Self-expandable filler for mitigating paravalvular leak
US11006939B2 (en) 2017-12-08 2021-05-18 Tendyne Holdings, Inc. Introducer sheath with seal and methods of using the same
US10898326B2 (en) 2018-02-20 2021-01-26 St. Jude Medical, Cardiology Division, Inc. Crimping heart valve with nitinol braid
US11813413B2 (en) 2018-03-27 2023-11-14 St. Jude Medical, Cardiology Division, Inc. Radiopaque outer cuff for transcatheter valve
US11318011B2 (en) 2018-04-27 2022-05-03 Edwards Lifesciences Corporation Mechanically expandable heart valve with leaflet clamps
US11844914B2 (en) 2018-06-05 2023-12-19 Edwards Lifesciences Corporation Removable volume indicator for syringe
US11284996B2 (en) 2018-09-20 2022-03-29 St. Jude Medical, Cardiology Division, Inc. Attachment of leaflets to prosthetic heart valve
US11364117B2 (en) 2018-10-15 2022-06-21 St. Jude Medical, Cardiology Division, Inc. Braid connections for prosthetic heart valves
CN112867468A (zh) 2018-10-19 2021-05-28 爱德华兹生命科学公司 具有非圆柱形框架的假体心脏瓣膜
US11779728B2 (en) 2018-11-01 2023-10-10 Edwards Lifesciences Corporation Introducer sheath with expandable introducer
CA3118599A1 (fr) 2018-11-08 2020-05-14 Neovasc Tiara Inc. Deploiement ventriculaire d'une prothese de valvule mitrale transcatheter
WO2020102320A2 (fr) 2018-11-14 2020-05-22 Medtronic Inc. Dispositifs et méthodes de préparation d'une valvule pour une procédure de remplacement de valvule par transcathéter
US11471277B2 (en) 2018-12-10 2022-10-18 St. Jude Medical, Cardiology Division, Inc. Prosthetic tricuspid valve replacement design
WO2020139542A1 (fr) 2018-12-26 2020-07-02 St. Jude Medical, Cardiology Division, Inc. Manchon externe surélevé pour réduire une fuite paravalvulaire et augmenter la durée de vie d'endoprothèse
EP3902597B1 (fr) 2018-12-28 2023-06-28 St. Jude Medical, Cardiology Division, Inc. Poignée de commande pour la déviation ou la rotation sélective d'un cathéter
US11648109B2 (en) 2019-02-04 2023-05-16 Medtronic, Inc. Balloon expandable frame for transcatheter implantation of a cardiac valve prosthesis
JP2022527076A (ja) 2019-03-26 2022-05-30 エドワーズ ライフサイエンシーズ コーポレイション 人工心臓弁
EP3946163A4 (fr) 2019-04-01 2022-12-21 Neovasc Tiara Inc. Valve prothétique déployable de manière contrôlable
AU2020271896B2 (en) 2019-04-10 2022-10-13 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
US11771554B2 (en) 2019-05-17 2023-10-03 Medtronic, Inc. Supra annular tapered balloon expandable stent for transcatheter implantation of a cardiac valve prosthesis
EP3972673A4 (fr) 2019-05-20 2023-06-07 Neovasc Tiara Inc. Dispositif d'introduction avec mécanisme d'hémostase
AU2020295566B2 (en) 2019-06-20 2023-07-20 Neovasc Tiara Inc. Low profile prosthetic mitral valve
EP4003230A1 (fr) 2019-07-31 2022-06-01 St. Jude Medical, Cardiology Division, Inc. Conception alternée d'endoprothèse caf pour rvac
US11648110B2 (en) 2019-12-05 2023-05-16 Tendyne Holdings, Inc. Braided anchor for mitral valve
US11648114B2 (en) 2019-12-20 2023-05-16 Tendyne Holdings, Inc. Distally loaded sheath and loading funnel
US11951002B2 (en) 2020-03-30 2024-04-09 Tendyne Holdings, Inc. Apparatus and methods for valve and tether fixation
CN116194065A (zh) 2020-06-18 2023-05-30 爱德华兹生命科学公司 折绉方法
US11678980B2 (en) 2020-08-19 2023-06-20 Tendyne Holdings, Inc. Fully-transseptal apical pad with pulley for tensioning
CN216933623U (zh) 2020-08-24 2022-07-12 爱德华兹生命科学公司 用于递送设备的球囊覆盖物和组件
CN216455494U (zh) 2020-08-31 2022-05-10 爱德华兹生命科学公司 用于将假体植入物卷曲到递送装置的系统和卷曲系统

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156610A (en) * 1989-08-18 1992-10-20 Evi Corporation Catheter atherotome
WO1993001768A1 (fr) 1991-07-16 1993-02-04 Stevens John H Remplacement endosvasculaire d'une valvule sigmoïde aortique
US5370647A (en) * 1991-01-23 1994-12-06 Surgical Innovations, Inc. Tissue and organ extractor
WO1997028807A1 (fr) 1996-02-08 1997-08-14 Ngk Insulators, Ltd. Substance anticancereuse inhibant le processus metastatique cancereux
US5814097A (en) 1992-12-03 1998-09-29 Heartport, Inc. Devices and methods for intracardiac procedures
WO1999012483A1 (fr) * 1997-09-11 1999-03-18 Genzyme Corporation Dispositif chirurgical endoscopique de rotation d'implant pouvant etre articule et mode d'utilisation de ce dispositif
WO1999015227A1 (fr) * 1997-09-26 1999-04-01 Cardeon Corporation Instrument de catheterisation de phase principale
US5924424A (en) * 1993-02-22 1999-07-20 Heartport, Inc. Method and apparatus for thoracoscopic intracardiac procedures
US5968064A (en) * 1997-02-28 1999-10-19 Lumend, Inc. Catheter system for treating a vascular occlusion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62233168A (ja) * 1986-04-03 1987-10-13 オリンパス光学工業株式会社 カテ−テル
US5558644A (en) * 1991-07-16 1996-09-24 Heartport, Inc. Retrograde delivery catheter and method for inducing cardioplegic arrest
US5972030A (en) * 1993-02-22 1999-10-26 Heartport, Inc. Less-invasive devices and methods for treatment of cardiac valves
US5372601A (en) * 1993-03-30 1994-12-13 Lary; Banning G. Longitudinal reciprocating incisor
US5984959A (en) * 1997-09-19 1999-11-16 United States Surgical Heart valve replacement tools and procedures
US6096074A (en) * 1998-01-27 2000-08-01 United States Surgical Stapling apparatus and method for heart valve replacement
US6602288B1 (en) * 2000-10-05 2003-08-05 Edwards Lifesciences Corporation Minimally-invasive annuloplasty repair segment delivery template, system and method of use
US6425902B1 (en) * 2001-05-04 2002-07-30 Cardiomend Llc Surgical instrument for heart valve reconstruction

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156610A (en) * 1989-08-18 1992-10-20 Evi Corporation Catheter atherotome
US5370647A (en) * 1991-01-23 1994-12-06 Surgical Innovations, Inc. Tissue and organ extractor
WO1993001768A1 (fr) 1991-07-16 1993-02-04 Stevens John H Remplacement endosvasculaire d'une valvule sigmoïde aortique
US5370685A (en) 1991-07-16 1994-12-06 Stanford Surgical Technologies, Inc. Endovascular aortic valve replacement
US5545214A (en) 1991-07-16 1996-08-13 Heartport, Inc. Endovascular aortic valve replacement
US5814097A (en) 1992-12-03 1998-09-29 Heartport, Inc. Devices and methods for intracardiac procedures
US5924424A (en) * 1993-02-22 1999-07-20 Heartport, Inc. Method and apparatus for thoracoscopic intracardiac procedures
WO1997028807A1 (fr) 1996-02-08 1997-08-14 Ngk Insulators, Ltd. Substance anticancereuse inhibant le processus metastatique cancereux
US5968064A (en) * 1997-02-28 1999-10-19 Lumend, Inc. Catheter system for treating a vascular occlusion
WO1999012483A1 (fr) * 1997-09-11 1999-03-18 Genzyme Corporation Dispositif chirurgical endoscopique de rotation d'implant pouvant etre articule et mode d'utilisation de ce dispositif
WO1999015227A1 (fr) * 1997-09-26 1999-04-01 Cardeon Corporation Instrument de catheterisation de phase principale

Cited By (379)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10485976B2 (en) 1998-04-30 2019-11-26 Medtronic, Inc. Intracardiovascular access (ICVA™) system
US8597226B2 (en) 1998-09-10 2013-12-03 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US8216174B2 (en) 1998-09-10 2012-07-10 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US7704222B2 (en) 1998-09-10 2010-04-27 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US7736327B2 (en) 1998-09-10 2010-06-15 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US9060856B2 (en) 1999-11-17 2015-06-23 Medtronic Corevalve Llc Transcatheter heart valves
US8998979B2 (en) 1999-11-17 2015-04-07 Medtronic Corevalve Llc Transcatheter heart valves
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8986329B2 (en) 1999-11-17 2015-03-24 Medtronic Corevalve Llc Methods for transluminal delivery of prosthetic valves
US9962258B2 (en) 1999-11-17 2018-05-08 Medtronic CV Luxembourg S.a.r.l. Transcatheter heart valves
US10219901B2 (en) 1999-11-17 2019-03-05 Medtronic CV Luxembourg S.a.r.l. Prosthetic valve for transluminal delivery
US9949831B2 (en) 2000-01-19 2018-04-24 Medtronics, Inc. Image-guided heart valve placement
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US10022220B2 (en) 2000-04-06 2018-07-17 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US10278805B2 (en) 2000-08-18 2019-05-07 Atritech, Inc. Expandable implant devices for filtering blood flow from atrial appendages
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8206438B2 (en) 2001-03-23 2012-06-26 Edwards Lifesciences Corporation Prosthetic heart valve having flared outflow section
US8956402B2 (en) 2001-06-29 2015-02-17 Medtronic, Inc. Apparatus for replacing a cardiac valve
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US11007052B2 (en) 2001-08-03 2021-05-18 Jenavalve Technology, Inc. Devices useful for implantation at a heart valve
US8579965B2 (en) 2001-08-03 2013-11-12 Jenavalve Technology, Inc. Methods of implanting an implantation device
US8303653B2 (en) 2001-08-03 2012-11-06 Philipp Bonhoeffer Implant implantation unit and procedure for implanting the unit
US9949824B2 (en) 2001-08-03 2018-04-24 Jenavalve Technology, Inc. Devices useful for implantation at a heart valve
US9889002B2 (en) 2001-08-03 2018-02-13 Jenavalve Technology, Inc. Devices useful for implantation at a heart valve
US8216301B2 (en) 2001-08-03 2012-07-10 Philipp Bonhoeffer Implant implantation unit
US8206437B2 (en) 2001-08-03 2012-06-26 Philipp Bonhoeffer Implant implantation unit and procedure for implanting the unit
EP2266504B1 (fr) * 2001-08-03 2017-03-29 JenaValve Technology Inc. Dispositif et méthode d'implantation d'une endoprothèse
US8585756B2 (en) 2001-08-03 2013-11-19 Jenavalve Technology, Inc. Methods of treating valves
US10342657B2 (en) 2001-09-07 2019-07-09 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9629717B2 (en) 2001-10-11 2017-04-25 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US11123182B2 (en) 2001-10-11 2021-09-21 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US11166810B2 (en) 2001-10-11 2021-11-09 Edwards Lifesciences Pvt, Inc. Implantable prosthetic valve
US10052203B2 (en) 2001-10-11 2018-08-21 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9339383B2 (en) 2001-10-11 2016-05-17 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9937039B2 (en) 2001-10-11 2018-04-10 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9393113B2 (en) 2003-12-23 2016-07-19 Boston Scientific Scimed Inc. Retrievable heart valve anchor and method
US9872768B2 (en) 2003-12-23 2018-01-23 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
EP1702247A2 (fr) * 2003-12-23 2006-09-20 Sadra Medical, Inc. Valvule cardiaque repositionnable
US9861476B2 (en) 2003-12-23 2018-01-09 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
EP1701668A1 (fr) * 2003-12-23 2006-09-20 Sadra Medical, Inc. Appareils et procedes de protection contre une embolisation au cours du remplacement endovasculaire de la valvule cardiaque
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US10772724B2 (en) 2003-12-23 2020-09-15 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US9956075B2 (en) 2003-12-23 2018-05-01 Boston Scientific Scimed Inc. Methods and apparatus for endovascularly replacing a heart valve
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
EP1701668A4 (fr) * 2003-12-23 2011-09-21 Sadra Medical Inc Appareils et procedes de protection contre une embolisation au cours du remplacement endovasculaire de la valvule cardiaque
EP1702247A4 (fr) * 2003-12-23 2011-09-21 Sadra Medical Inc Valvule cardiaque repositionnable
US10206774B2 (en) 2003-12-23 2019-02-19 Boston Scientific Scimed Inc. Low profile heart valve and delivery system
US9585750B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US11285002B2 (en) 2003-12-23 2022-03-29 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US10258465B2 (en) 2003-12-23 2019-04-16 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US9308085B2 (en) 2003-12-23 2016-04-12 Boston Scientific Scimed, Inc. Repositionable heart valve and method
US11185408B2 (en) 2003-12-23 2021-11-30 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8951299B2 (en) 2003-12-23 2015-02-10 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US10314695B2 (en) 2003-12-23 2019-06-11 Boston Scientific Scimed Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US9320599B2 (en) 2003-12-23 2016-04-26 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US11696825B2 (en) 2003-12-23 2023-07-11 Boston Scientific Scimed, Inc. Replacement valve and anchor
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US9532872B2 (en) 2003-12-23 2017-01-03 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US10335273B2 (en) 2003-12-23 2019-07-02 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
US9358110B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US10357359B2 (en) 2003-12-23 2019-07-23 Boston Scientific Scimed Inc Methods and apparatus for endovascularly replacing a patient's heart valve
US10925724B2 (en) 2003-12-23 2021-02-23 Boston Scientific Scimed, Inc. Replacement valve and anchor
US10413409B2 (en) 2003-12-23 2019-09-17 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US10413412B2 (en) 2003-12-23 2019-09-17 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US10478289B2 (en) 2003-12-23 2019-11-19 Boston Scientific Scimed, Inc. Replacement valve and anchor
US10426608B2 (en) 2003-12-23 2019-10-01 Boston Scientific Scimed, Inc. Repositionable heart valve
US10716663B2 (en) 2003-12-23 2020-07-21 Boston Scientific Scimed, Inc. Methods and apparatus for performing valvuloplasty
US9387076B2 (en) 2003-12-23 2016-07-12 Boston Scientific Scimed Inc. Medical devices and delivery systems for delivering medical devices
US8535373B2 (en) 2004-03-03 2013-09-17 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US9867695B2 (en) 2004-03-03 2018-01-16 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US11484405B2 (en) 2004-06-16 2022-11-01 Boston Scientific Scimed, Inc. Everting heart valve
US9744035B2 (en) 2004-06-16 2017-08-29 Boston Scientific Scimed, Inc. Everting heart valve
EP2481375A2 (fr) * 2004-10-02 2012-08-01 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
EP2481375A3 (fr) * 2004-10-02 2013-12-04 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
US10531952B2 (en) 2004-11-05 2020-01-14 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US10492906B2 (en) 2005-01-20 2019-12-03 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
US11517431B2 (en) 2005-01-20 2022-12-06 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
US9788945B2 (en) 2005-01-20 2017-10-17 Jenavalve Technology, Inc. Systems for implanting an endoprosthesis
US9775705B2 (en) 2005-01-20 2017-10-03 Jenavalve Technology, Inc. Methods of implanting an endoprosthesis
US8679174B2 (en) 2005-01-20 2014-03-25 JenaValve Technology, GmbH Catheter for the transvascular implantation of prosthetic heart valves
US9895223B2 (en) 2005-02-10 2018-02-20 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8920492B2 (en) 2005-02-10 2014-12-30 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8540768B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US9486313B2 (en) 2005-02-10 2016-11-08 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US9649495B2 (en) 2005-04-25 2017-05-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US10549101B2 (en) 2005-04-25 2020-02-04 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US11284997B2 (en) 2005-05-13 2022-03-29 Medtronic CV Luxembourg S.a.r.l Heart valve prosthesis and methods of manufacture and use
USD812226S1 (en) 2005-05-13 2018-03-06 Medtronic Corevalve Llc Heart valve prosthesis
USD732666S1 (en) 2005-05-13 2015-06-23 Medtronic Corevalve, Inc. Heart valve prosthesis
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US10478291B2 (en) 2005-05-13 2019-11-19 Medtronic CV Luxembourg S.a.r.l Heart valve prosthesis and methods of manufacture and use
US9504564B2 (en) 2005-05-13 2016-11-29 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9393094B2 (en) 2005-09-13 2016-07-19 Boston Scientific Scimed, Inc. Two-part package for medical implant
US10370150B2 (en) 2005-09-13 2019-08-06 Boston Scientific Scimed Inc. Two-part package for medical implant
US9855142B2 (en) 2005-10-28 2018-01-02 JenaValve Technologies, Inc. Device for the implantation and fixation of prosthetic valves
US8834561B2 (en) 2005-10-28 2014-09-16 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
USRE45790E1 (en) 2005-10-28 2015-11-03 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US11116628B2 (en) 2005-10-28 2021-09-14 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
US9044320B2 (en) 2005-10-28 2015-06-02 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
USRE45962E1 (en) 2005-10-28 2016-04-05 Jenavalve Technology Gmbh Device for the implantation and fixation of prosthetic valves
US10363134B2 (en) 2005-10-28 2019-07-30 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
US9402717B2 (en) 2005-10-28 2016-08-02 Jenavalve Technology, Inc. Device for the implantation and fixation of prosthetic valves
US8062355B2 (en) 2005-11-04 2011-11-22 Jenavalve Technology, Inc. Self-expandable medical instrument for treating defects in a patient's heart
US9486336B2 (en) 2005-11-10 2016-11-08 Edwards Lifesciences Cardiaq Llc Prosthesis having a plurality of distal and proximal prongs
US9433514B2 (en) 2005-11-10 2016-09-06 Edwards Lifesciences Cardiaq Llc Method of securing a prosthesis
US8092520B2 (en) 2005-11-10 2012-01-10 CardiAQ Technologies, Inc. Vascular prosthesis connecting stent
US10299922B2 (en) 2005-12-22 2019-05-28 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US10314701B2 (en) 2005-12-22 2019-06-11 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US10265167B2 (en) 2005-12-22 2019-04-23 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US9839515B2 (en) 2005-12-22 2017-12-12 Symetis, SA Stent-valves for valve replacement and associated methods and systems for surgery
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US10058421B2 (en) 2006-03-28 2018-08-28 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US7815676B2 (en) 2006-07-07 2010-10-19 The Cleveland Clinic Foundation Apparatus and method for assisting in the removal of a cardiac valve
US11304801B2 (en) 2006-09-19 2022-04-19 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US10195033B2 (en) 2006-09-19 2019-02-05 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US8771346B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthetic fixation techniques using sandwiching
US11304802B2 (en) 2006-09-19 2022-04-19 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US10543077B2 (en) 2006-09-19 2020-01-28 Medtronic, Inc. Sinus-engaging valve fixation member
US9301834B2 (en) 2006-09-19 2016-04-05 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US9913714B2 (en) 2006-09-19 2018-03-13 Medtronic, Inc. Sinus-engaging valve fixation member
US11304800B2 (en) 2006-09-19 2022-04-19 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8876894B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Leaflet-sensitive valve fixation member
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US10004601B2 (en) 2006-09-19 2018-06-26 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US9387071B2 (en) 2006-09-19 2016-07-12 Medtronic, Inc. Sinus-engaging valve fixation member
US9827097B2 (en) 2006-09-19 2017-11-28 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US9642704B2 (en) 2006-09-19 2017-05-09 Medtronic Ventor Technologies Ltd. Catheter for implanting a valve prosthesis
US9138312B2 (en) 2006-09-19 2015-09-22 Medtronic Ventor Technologies Ltd. Valve prostheses
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US8771345B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9295551B2 (en) 2007-04-13 2016-03-29 Jenavalve Technology Gmbh Methods of implanting an endoprosthesis
US9339386B2 (en) 2007-04-13 2016-05-17 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US10543084B2 (en) 2007-04-13 2020-01-28 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US11357624B2 (en) 2007-04-13 2022-06-14 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9918835B2 (en) 2007-04-13 2018-03-20 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficency
US9445896B2 (en) 2007-04-13 2016-09-20 Jenavalve Technology, Inc. Methods for treating a heart valve insufficiency or stenosis
US7914575B2 (en) 2007-04-13 2011-03-29 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US8685085B2 (en) 2007-04-13 2014-04-01 JenaValve Technologies GmbH Medical device for treating a heart valve insufficiency
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9585754B2 (en) 2007-04-20 2017-03-07 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US10188516B2 (en) 2007-08-20 2019-01-29 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US10856970B2 (en) 2007-10-10 2020-12-08 Medtronic Ventor Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US10966823B2 (en) 2007-10-12 2021-04-06 Sorin Group Italia S.R.L. Expandable valve prosthesis with sealing mechanism
US11259919B2 (en) 2008-01-24 2022-03-01 Medtronic, Inc. Stents for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US10646335B2 (en) 2008-01-24 2020-05-12 Medtronic, Inc. Stents for prosthetic heart valves
US11284999B2 (en) 2008-01-24 2022-03-29 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US9925079B2 (en) 2008-01-24 2018-03-27 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US10016274B2 (en) 2008-01-24 2018-07-10 Medtronic, Inc. Stent for prosthetic heart valves
US10639182B2 (en) 2008-01-24 2020-05-05 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US11786367B2 (en) 2008-01-24 2023-10-17 Medtronic, Inc. Stents for prosthetic heart valves
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US11607311B2 (en) 2008-01-24 2023-03-21 Medtronic, Inc. Stents for prosthetic heart valves
US11083573B2 (en) 2008-01-24 2021-08-10 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US11951007B2 (en) 2008-01-24 2024-04-09 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US10820993B2 (en) 2008-01-24 2020-11-03 Medtronic, Inc. Stents for prosthetic heart valves
US10758343B2 (en) 2008-01-24 2020-09-01 Medtronic, Inc. Stent for prosthetic heart valves
US9265631B2 (en) 2008-02-26 2016-02-23 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US10702382B2 (en) 2008-02-26 2020-07-07 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9439759B2 (en) 2008-02-26 2016-09-13 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9867699B2 (en) 2008-02-26 2018-01-16 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US9877828B2 (en) 2008-02-26 2018-01-30 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US10575947B2 (en) 2008-02-26 2020-03-03 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11564794B2 (en) 2008-02-26 2023-01-31 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9987133B2 (en) 2008-02-26 2018-06-05 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8790395B2 (en) 2008-02-26 2014-07-29 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US10154901B2 (en) 2008-02-26 2018-12-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9707075B2 (en) 2008-02-26 2017-07-18 Jenavalve Technology, Inc. Endoprosthesis for implantation in the heart of a patient
US11154398B2 (en) 2008-02-26 2021-10-26 JenaValve Technology. Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US11602430B2 (en) 2008-03-18 2023-03-14 Medtronic Ventor Technologies Ltd. Valve suturing and implantation procedures
US11278408B2 (en) 2008-03-18 2022-03-22 Medtronic Venter Technologies, Ltd. Valve suturing and implantation procedures
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US10856979B2 (en) 2008-03-18 2020-12-08 Medtronic Ventor Technologies Ltd. Valve suturing and implantation procedures
US10245142B2 (en) 2008-04-08 2019-04-02 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US9943407B2 (en) 2008-09-15 2018-04-17 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US10806570B2 (en) 2008-09-15 2020-10-20 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US11026786B2 (en) 2008-09-15 2021-06-08 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US11166815B2 (en) 2008-09-17 2021-11-09 Medtronic CV Luxembourg S.a.r.l Delivery system for deployment of medical devices
US10321997B2 (en) 2008-09-17 2019-06-18 Medtronic CV Luxembourg S.a.r.l. Delivery system for deployment of medical devices
US9456896B2 (en) 2008-09-29 2016-10-04 Edwards Lifesciences Cardiaq Llc Body cavity prosthesis
US9339377B2 (en) 2008-09-29 2016-05-17 Edwards Lifesciences Cardiaq Llc Body cavity prosthesis
US8894702B2 (en) 2008-09-29 2014-11-25 Cardiaq Valve Technologies, Inc. Replacement heart valve and method
US9597183B2 (en) 2008-10-01 2017-03-21 Edwards Lifesciences Cardiaq Llc Delivery system for vascular implant
US8911455B2 (en) 2008-10-01 2014-12-16 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8337541B2 (en) 2008-10-01 2012-12-25 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US10098733B2 (en) 2008-12-23 2018-10-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US9333074B2 (en) 2009-04-15 2016-05-10 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery system
US9339379B2 (en) 2009-04-15 2016-05-17 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery system
US9339380B2 (en) 2009-04-15 2016-05-17 Edwards Lifesciences Cardiaq Llc Vascular implant
US9333073B2 (en) 2009-04-15 2016-05-10 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery method
US9585747B2 (en) 2009-04-15 2017-03-07 Edwards Lifesciences Cardiaq Llc Vascular implant
US9339378B2 (en) 2009-04-15 2016-05-17 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery system
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US8468667B2 (en) 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
US9480560B2 (en) 2009-09-29 2016-11-01 Edwards Lifesciences Cardiaq Llc Method of securing an intralumenal frame assembly
US10166097B2 (en) 2009-09-29 2019-01-01 Edwards Lifesciences Cardiaq Llc Replacement heart valve and method
US9949827B2 (en) 2009-09-29 2018-04-24 Edwards Lifesciences Cardiaq Llc Replacement heart valves, delivery devices and methods
US9023100B2 (en) 2009-09-29 2015-05-05 Cardiaq Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US10716665B2 (en) 2010-04-01 2020-07-21 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US9925044B2 (en) 2010-04-01 2018-03-27 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US11554010B2 (en) 2010-04-01 2023-01-17 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US11833041B2 (en) 2010-04-01 2023-12-05 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US11419720B2 (en) 2010-05-05 2022-08-23 Neovasc Tiara Inc. Transcatheter mitral valve prosthesis
US11432924B2 (en) 2010-05-05 2022-09-06 Neovasc Tiara Inc. Transcatheter mitral valve prosthesis
US9770329B2 (en) 2010-05-05 2017-09-26 Neovasc Tiara Inc. Transcatheter mitral valve prosthesis
US10449042B2 (en) 2010-05-05 2019-10-22 Neovasc Tiara Inc. Transcatheter mitral valve prosthesis
US11147669B2 (en) 2010-05-20 2021-10-19 Jenavalve Technology, Inc. Catheter system for introducing an expandable stent into the body of a patient
US10307251B2 (en) 2010-05-20 2019-06-04 Jenavalve Technology, Inc. Catheter system for introducing an expandable stent into the body of a patient
US9597182B2 (en) 2010-05-20 2017-03-21 Jenavalve Technology Inc. Catheter system for introducing an expandable stent into the body of a patient
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US10603164B2 (en) 2010-05-25 2020-03-31 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US11589981B2 (en) 2010-05-25 2023-02-28 Jenavalve Technology, Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
US9744031B2 (en) 2010-05-25 2017-08-29 Jenavalve Technology, Inc. Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent
US11786368B2 (en) 2010-09-01 2023-10-17 Medtronic Vascular Galway Prosthetic valve support structure
US9918833B2 (en) 2010-09-01 2018-03-20 Medtronic Vascular Galway Prosthetic valve support structure
US10835376B2 (en) 2010-09-01 2020-11-17 Medtronic Vascular Galway Prosthetic valve support structure
US10869760B2 (en) 2010-09-10 2020-12-22 Symetis Sa Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US10201418B2 (en) 2010-09-10 2019-02-12 Symetis, SA Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US11903825B2 (en) 2011-02-23 2024-02-20 Edwards Lifesciences Cardiaq Llc Replacement heart valve and method
US10779938B2 (en) 2011-02-23 2020-09-22 Edwards Lifesciences Cardiaq Llc Replacement heart valve and method
US8728155B2 (en) 2011-03-21 2014-05-20 Cephea Valve Technologies, Inc. Disk-based valve apparatus and method for the treatment of valve dysfunction
US10456255B2 (en) 2011-03-21 2019-10-29 Cephea Valve Technologies, Inc. Disk-based valve apparatus and method for the treatment of valve dysfunction
US11931252B2 (en) 2011-03-21 2024-03-19 Cephea Valve Technologies, Inc. Disk-based valve apparatus and method for the treatment of valve dysfunction
US9713529B2 (en) 2011-04-28 2017-07-25 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US11771544B2 (en) 2011-05-05 2023-10-03 Symetis Sa Method and apparatus for compressing/loading stent-valves
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9555219B2 (en) 2011-11-10 2017-01-31 Boston Scientific Scimed, Inc. Direct connect flush system
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US9642705B2 (en) 2011-11-15 2017-05-09 Boston Scientific Scimed Inc. Bond between components of a medical device
US10478300B2 (en) 2011-11-15 2019-11-19 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US11413139B2 (en) 2011-11-23 2022-08-16 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US10537422B2 (en) 2011-11-23 2020-01-21 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9138314B2 (en) 2011-12-29 2015-09-22 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US10172708B2 (en) 2012-01-25 2019-01-08 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
US10363133B2 (en) 2012-02-14 2019-07-30 Neovac Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US11497602B2 (en) 2012-02-14 2022-11-15 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US10016275B2 (en) 2012-05-30 2018-07-10 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US11389294B2 (en) 2012-05-30 2022-07-19 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US10314705B2 (en) 2012-05-30 2019-06-11 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US10940001B2 (en) 2012-05-30 2021-03-09 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US11617650B2 (en) 2012-05-30 2023-04-04 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US11382739B2 (en) 2012-06-19 2022-07-12 Boston Scientific Scimed, Inc. Replacement heart valve
US10555809B2 (en) 2012-06-19 2020-02-11 Boston Scientific Scimed, Inc. Replacement heart valve
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US10383728B2 (en) 2013-04-04 2019-08-20 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US11389291B2 (en) 2013-04-04 2022-07-19 Neovase Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10568739B2 (en) 2013-05-03 2020-02-25 Medtronic, Inc. Valve delivery tool
US11793637B2 (en) 2013-05-03 2023-10-24 Medtronic, Inc. Valve delivery tool
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9554899B2 (en) 2013-07-17 2017-01-31 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US11510780B2 (en) 2013-07-17 2022-11-29 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US9561103B2 (en) 2013-07-17 2017-02-07 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US10154906B2 (en) 2013-07-17 2018-12-18 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US10149761B2 (en) 2013-07-17 2018-12-11 Cephea Valve Technlologies, Inc. System and method for cardiac valve repair and replacement
US10624742B2 (en) 2013-07-17 2020-04-21 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US9724083B2 (en) 2013-07-26 2017-08-08 Edwards Lifesciences Cardiaq Llc Systems and methods for sealing openings in an anatomical wall
US10433954B2 (en) 2013-08-30 2019-10-08 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US11185405B2 (en) 2013-08-30 2021-11-30 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US10433953B2 (en) 2014-12-09 2019-10-08 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US11147665B2 (en) 2014-12-09 2021-10-19 Cepha Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US9439757B2 (en) 2014-12-09 2016-09-13 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US10548721B2 (en) 2014-12-09 2020-02-04 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US10869755B2 (en) 2014-12-09 2020-12-22 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US9492273B2 (en) 2014-12-09 2016-11-15 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US10449043B2 (en) 2015-01-16 2019-10-22 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US11337800B2 (en) 2015-05-01 2022-05-24 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10709555B2 (en) 2015-05-01 2020-07-14 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10555808B2 (en) 2015-05-14 2020-02-11 Cephea Valve Technologies, Inc. Replacement mitral valves
US11617646B2 (en) 2015-05-14 2023-04-04 Cephea Valve Technologies, Inc. Replacement mitral valves
US10143552B2 (en) 2015-05-14 2018-12-04 Cephea Valve Technologies, Inc. Replacement mitral valves
US10470881B2 (en) 2015-05-14 2019-11-12 Cephea Valve Technologies, Inc. Replacement mitral valves
US11786373B2 (en) 2015-05-14 2023-10-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US10849746B2 (en) 2015-05-14 2020-12-01 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US11730595B2 (en) 2015-07-02 2023-08-22 Boston Scientific Scimed, Inc. Adjustable nosecone
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10856973B2 (en) 2015-08-12 2020-12-08 Boston Scientific Scimed, Inc. Replacement heart valve implant
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10779940B2 (en) 2015-09-03 2020-09-22 Boston Scientific Scimed, Inc. Medical device handle
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US11382742B2 (en) 2016-05-13 2022-07-12 Boston Scientific Scimed, Inc. Medical device handle
US10245136B2 (en) 2016-05-13 2019-04-02 Boston Scientific Scimed Inc. Containment vessel with implant sheathing guide
US20170325938A1 (en) 2016-05-16 2017-11-16 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US10709552B2 (en) 2016-05-16 2020-07-14 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US11331187B2 (en) 2016-06-17 2022-05-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US11058535B2 (en) 2017-01-23 2021-07-13 Cephea Valve Technologies, Inc. Replacement mitral valves
US10828153B2 (en) 2017-01-23 2020-11-10 Cephea Valve Technologies, Inc. Replacement mitral valves
US11090158B2 (en) 2017-01-23 2021-08-17 Cephea Valve Technologies, Inc. Replacement mitral valves
US10368990B2 (en) 2017-01-23 2019-08-06 Cephea Valve Technologies, Inc. Replacement mitral valves
US11633278B2 (en) 2017-01-23 2023-04-25 Cephea Valve Technologies, Inc. Replacement mitral valves
US10568737B2 (en) 2017-01-23 2020-02-25 Cephea Valve Technologies, Inc. Replacement mitral valves
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11246625B2 (en) 2018-01-19 2022-02-15 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
US11191641B2 (en) 2018-01-19 2021-12-07 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
US11147668B2 (en) 2018-02-07 2021-10-19 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
US11439732B2 (en) 2018-02-26 2022-09-13 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11504231B2 (en) 2018-05-23 2022-11-22 Corcym S.R.L. Cardiac valve prosthesis
US11241310B2 (en) 2018-06-13 2022-02-08 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
US11969341B2 (en) 2022-11-18 2024-04-30 Corcym S.R.L. Cardiac valve prosthesis

Also Published As

Publication number Publication date
AU1713201A (en) 2001-05-30
AU767710B2 (en) 2003-11-20
US6830584B1 (en) 2004-12-14
DE60017189D1 (de) 2005-02-03
EP1233731A1 (fr) 2002-08-28
FR2800984A1 (fr) 2001-05-18
ES2233482T3 (es) 2005-06-16
EP1233731B1 (fr) 2004-12-29
ATE285729T1 (de) 2005-01-15
FR2800984B1 (fr) 2001-12-14
JP2003513751A (ja) 2003-04-15
CA2389713C (fr) 2008-09-02
DE60017189T2 (de) 2005-09-22
CA2389713A1 (fr) 2001-05-25

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