WO2001030448A1 - Method and compositions for administering taxanes orally to human patients - Google Patents
Method and compositions for administering taxanes orally to human patients Download PDFInfo
- Publication number
- WO2001030448A1 WO2001030448A1 PCT/US2000/029633 US0029633W WO0130448A1 WO 2001030448 A1 WO2001030448 A1 WO 2001030448A1 US 0029633 W US0029633 W US 0029633W WO 0130448 A1 WO0130448 A1 WO 0130448A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- taxane
- paclitaxel
- oral
- administered
- formulation
- Prior art date
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
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JP2001532859A JP2003512443A (en) | 1999-10-27 | 2000-10-27 | Methods and compositions for oral administration of taxanes to human patients |
SK582-2002A SK5822002A3 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
HU0203303A HUP0203303A3 (en) | 1999-10-27 | 2000-10-27 | Compositions for administering taxanes orally to human patients |
CA002389583A CA2389583A1 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
BR0015149-1A BR0015149A (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
IL14936000A IL149360A0 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
AU11042/01A AU1104201A (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
MXPA02004164A MXPA02004164A (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients. |
EP00972373A EP1225956A1 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
NO20022008A NO20022008L (en) | 1999-10-27 | 2002-04-26 | Methods and Preparations for Oral Administration of Taxanes to Human Patients |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US16231099P | 1999-10-27 | 1999-10-27 | |
US60/162,310 | 1999-10-27 |
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WO2001030448A1 true WO2001030448A1 (en) | 2001-05-03 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/US2000/029633 WO2001030448A1 (en) | 1999-10-27 | 2000-10-27 | Method and compositions for administering taxanes orally to human patients |
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Country | Link |
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EP (1) | EP1225956A1 (en) |
JP (1) | JP2003512443A (en) |
KR (1) | KR20030019296A (en) |
CN (1) | CN1450923A (en) |
AU (1) | AU1104201A (en) |
BR (1) | BR0015149A (en) |
CA (1) | CA2389583A1 (en) |
CO (1) | CO5251425A1 (en) |
CZ (1) | CZ20021484A3 (en) |
HU (1) | HUP0203303A3 (en) |
IL (1) | IL149360A0 (en) |
MX (1) | MXPA02004164A (en) |
NO (1) | NO20022008L (en) |
PL (1) | PL354777A1 (en) |
RU (1) | RU2002113659A (en) |
SK (1) | SK5822002A3 (en) |
WO (1) | WO2001030448A1 (en) |
ZA (1) | ZA200203358B (en) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
US6750246B1 (en) | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
US6919370B2 (en) | 2000-11-28 | 2005-07-19 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
EP1569620A1 (en) * | 2002-10-30 | 2005-09-07 | Spherics, Inc. | Nanoparticulate bioactive agents |
US7345093B2 (en) | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
US7659310B2 (en) | 2004-04-27 | 2010-02-09 | Formatech, Inc. | Methods of enhancing solubility of agents |
US8591942B2 (en) | 2009-09-23 | 2013-11-26 | Indu JAVERI | Methods for the preparation of liposomes comprising docetaxel |
US8940786B2 (en) | 2012-10-01 | 2015-01-27 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane nanodispersion formulations and methods of using the same |
US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
US10842770B2 (en) | 2010-05-03 | 2020-11-24 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
EP4059497A1 (en) * | 2021-03-17 | 2022-09-21 | Dompé farmaceutici S.p.a. | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
WO2022195017A1 (en) * | 2021-03-17 | 2022-09-22 | Dompe' Farmaceutici Spa | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR050043A1 (en) * | 2004-08-03 | 2006-09-20 | Novartis Ag | METHODS TO IMPROVE BIODISPONIBILITY AND PHARMACEUTICAL COMPOSITION FOR CARDIOVASCULAR DISORDERS |
CN101513395B (en) * | 2008-02-20 | 2011-01-12 | 单宝华 | Taxol double-layer soft capsule oral preparation medicament |
JO3737B1 (en) * | 2015-07-21 | 2021-01-31 | Athenex Therapeutics Ltd | THERAPEUTIC COMBINATIONS OF ORALLY ADMINISTERED PACLITAXEL AND A P-gp INHIBITOR FOR THE TREATMENT OF CANCER |
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WO1997015269A2 (en) * | 1995-10-26 | 1997-05-01 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
WO1997027855A1 (en) * | 1996-01-31 | 1997-08-07 | Bristol-Myers Squibb Company | A method of making pharmaceutically active taxanes orally bioavailable |
WO1997048689A1 (en) * | 1996-06-17 | 1997-12-24 | Eli Lilly And Company | Drug resistance and multidrug resistance modulators |
WO1998053811A1 (en) * | 1997-05-27 | 1998-12-03 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for administering taxanes orally to human patients |
WO1999012570A2 (en) * | 1997-09-05 | 1999-03-18 | Glaxo Group Limited | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
WO1999049848A1 (en) * | 1998-04-01 | 1999-10-07 | Rtp Pharma Inc. | Anticancer compositions |
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WO2000078247A1 (en) * | 1995-10-26 | 2000-12-28 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
-
2000
- 2000-10-27 EP EP00972373A patent/EP1225956A1/en not_active Withdrawn
- 2000-10-27 WO PCT/US2000/029633 patent/WO2001030448A1/en not_active Application Discontinuation
- 2000-10-27 MX MXPA02004164A patent/MXPA02004164A/en unknown
- 2000-10-27 BR BR0015149-1A patent/BR0015149A/en not_active IP Right Cessation
- 2000-10-27 AU AU11042/01A patent/AU1104201A/en not_active Abandoned
- 2000-10-27 JP JP2001532859A patent/JP2003512443A/en active Pending
- 2000-10-27 CZ CZ20021484A patent/CZ20021484A3/en unknown
- 2000-10-27 CO CO00082131A patent/CO5251425A1/en not_active Application Discontinuation
- 2000-10-27 IL IL14936000A patent/IL149360A0/en unknown
- 2000-10-27 PL PL00354777A patent/PL354777A1/en not_active Application Discontinuation
- 2000-10-27 HU HU0203303A patent/HUP0203303A3/en unknown
- 2000-10-27 RU RU2002113659/15A patent/RU2002113659A/en not_active Application Discontinuation
- 2000-10-27 KR KR1020027005396A patent/KR20030019296A/en not_active Application Discontinuation
- 2000-10-27 SK SK582-2002A patent/SK5822002A3/en unknown
- 2000-10-27 CA CA002389583A patent/CA2389583A1/en not_active Abandoned
- 2000-10-27 CN CN00815924A patent/CN1450923A/en active Pending
-
2002
- 2002-04-26 ZA ZA200203358A patent/ZA200203358B/en unknown
- 2002-04-26 NO NO20022008A patent/NO20022008L/en not_active Application Discontinuation
Patent Citations (8)
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WO1997015269A2 (en) * | 1995-10-26 | 1997-05-01 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
WO2000078247A1 (en) * | 1995-10-26 | 2000-12-28 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
WO1997027855A1 (en) * | 1996-01-31 | 1997-08-07 | Bristol-Myers Squibb Company | A method of making pharmaceutically active taxanes orally bioavailable |
WO1997048689A1 (en) * | 1996-06-17 | 1997-12-24 | Eli Lilly And Company | Drug resistance and multidrug resistance modulators |
WO1998053811A1 (en) * | 1997-05-27 | 1998-12-03 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for administering taxanes orally to human patients |
WO1999012570A2 (en) * | 1997-09-05 | 1999-03-18 | Glaxo Group Limited | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
WO1999049848A1 (en) * | 1998-04-01 | 1999-10-07 | Rtp Pharma Inc. | Anticancer compositions |
WO2000071079A2 (en) * | 1999-05-21 | 2000-11-30 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6750246B1 (en) | 2000-02-03 | 2004-06-15 | Bristol-Myers Squibb Company | C-4 carbonate taxanes |
US6919370B2 (en) | 2000-11-28 | 2005-07-19 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
EP1569620A1 (en) * | 2002-10-30 | 2005-09-07 | Spherics, Inc. | Nanoparticulate bioactive agents |
EP1569620A4 (en) * | 2002-10-30 | 2006-03-22 | Spherics Inc | Nanoparticulate bioactive agents |
US7345093B2 (en) | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
US7659310B2 (en) | 2004-04-27 | 2010-02-09 | Formatech, Inc. | Methods of enhancing solubility of agents |
US7687458B2 (en) | 2004-04-27 | 2010-03-30 | Formatech, Inc. | Pharmaceutical compositions of hydrophobic compounds |
US8591942B2 (en) | 2009-09-23 | 2013-11-26 | Indu JAVERI | Methods for the preparation of liposomes comprising docetaxel |
US9402812B2 (en) | 2009-09-23 | 2016-08-02 | Indu JAVERI | Methods for the preparation of liposomes |
US9655846B2 (en) | 2009-09-23 | 2017-05-23 | Indu JAVERI | Methods for the preparation of liposomes comprising drugs |
US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
US10842770B2 (en) | 2010-05-03 | 2020-11-24 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
US8940786B2 (en) | 2012-10-01 | 2015-01-27 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane nanodispersion formulations and methods of using the same |
US9308195B2 (en) | 2012-10-01 | 2016-04-12 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane formulations and methods of using the same |
US9763880B2 (en) | 2012-10-01 | 2017-09-19 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane formulations and methods of using the same |
EP4059497A1 (en) * | 2021-03-17 | 2022-09-21 | Dompé farmaceutici S.p.a. | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
WO2022195017A1 (en) * | 2021-03-17 | 2022-09-22 | Dompe' Farmaceutici Spa | C5ar1 inhibitors for treating hypersensitivity reactions to taxanes |
Also Published As
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CA2389583A1 (en) | 2001-05-03 |
KR20030019296A (en) | 2003-03-06 |
MXPA02004164A (en) | 2002-10-17 |
BR0015149A (en) | 2002-10-29 |
HUP0203303A2 (en) | 2003-02-28 |
CZ20021484A3 (en) | 2003-12-17 |
IL149360A0 (en) | 2002-11-10 |
PL354777A1 (en) | 2004-02-23 |
ZA200203358B (en) | 2003-04-29 |
SK5822002A3 (en) | 2003-01-09 |
AU1104201A (en) | 2001-05-08 |
CO5251425A1 (en) | 2003-02-28 |
NO20022008D0 (en) | 2002-04-26 |
RU2002113659A (en) | 2004-01-27 |
HUP0203303A3 (en) | 2005-01-28 |
EP1225956A1 (en) | 2002-07-31 |
NO20022008L (en) | 2002-06-19 |
CN1450923A (en) | 2003-10-22 |
JP2003512443A (en) | 2003-04-02 |
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