WO2001029537A3 - Method and apparatus for monitoring solid phase chemical reactions - Google Patents
Method and apparatus for monitoring solid phase chemical reactions Download PDFInfo
- Publication number
- WO2001029537A3 WO2001029537A3 PCT/US2000/028218 US0028218W WO0129537A3 WO 2001029537 A3 WO2001029537 A3 WO 2001029537A3 US 0028218 W US0028218 W US 0028218W WO 0129537 A3 WO0129537 A3 WO 0129537A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- monitoring
- reaction
- solid phase
- phase chemical
- chemical reactions
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00691—Automatic using robots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00693—Means for quality control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00695—Synthesis control routines, e.g. using computer programs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00970831A EP1221037A2 (en) | 1999-10-15 | 2000-10-12 | Method and apparatus for monitoring solid phase chemical reactions |
JP2001532079A JP2003512615A (en) | 1999-10-15 | 2000-10-12 | Method and apparatus for monitoring solid phase chemical reactions |
AU80154/00A AU8015400A (en) | 1999-10-15 | 2000-10-12 | Method and apparatus for monitoring solid phase chemical reactions |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15967399P | 1999-10-15 | 1999-10-15 | |
US60/159,673 | 1999-10-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001029537A2 WO2001029537A2 (en) | 2001-04-26 |
WO2001029537A3 true WO2001029537A3 (en) | 2001-11-29 |
Family
ID=22573502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/028218 WO2001029537A2 (en) | 1999-10-15 | 2000-10-12 | Method and apparatus for monitoring solid phase chemical reactions |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1221037A2 (en) |
JP (1) | JP2003512615A (en) |
AU (1) | AU8015400A (en) |
WO (1) | WO2001029537A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7283245B2 (en) * | 2004-01-20 | 2007-10-16 | General Electric Company | Handheld device with a disposable element for chemical analysis of multiple analytes |
JP4765059B2 (en) * | 2005-02-10 | 2011-09-07 | 国立大学法人北海道大学 | Cognitive task response measurement system and cognitive task response measurement method |
DE102005048807B3 (en) * | 2005-10-10 | 2006-11-16 | Johann Wolfgang Goethe-Universität | Apparatus for quantitative or qualitative determination of infrared active contents of liquid based or non-liquid fluids |
TW200944776A (en) | 2008-03-04 | 2009-11-01 | Kurashiki Boseki Kk | Total reflection attenuation type far-ultraviolet spectroscopy and concentration measurement device using the spectroscopy |
JP5982663B2 (en) * | 2011-12-13 | 2016-08-31 | 株式会社Ube科学分析センター | Infrared spectrometer for measuring electrolyte of lithium ion secondary battery and measuring method thereof |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582809A (en) * | 1982-06-14 | 1986-04-15 | Myron J. Block | Apparatus including optical fiber for fluorescence immunoassay |
US5313264A (en) * | 1988-11-10 | 1994-05-17 | Pharmacia Biosensor Ab | Optical biosensor system |
WO1994019694A1 (en) * | 1993-02-19 | 1994-09-01 | Arris Pharmaceutical Corporation | Thin film hpmp matrix systems and methods for constructing and displaying ligands |
US5565324A (en) * | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
US5780603A (en) * | 1996-11-15 | 1998-07-14 | Synsorb Biotech, Inc. | Combinatorial synthesis of carbohydrate libraries |
US5817751A (en) * | 1994-06-23 | 1998-10-06 | Affymax Technologies N.V. | Method for synthesis of diketopiperazine and diketomorpholine derivatives |
WO1999004228A2 (en) * | 1997-07-16 | 1999-01-28 | Ljl Biosystems, Inc. | Light detection device |
US5942387A (en) * | 1996-08-26 | 1999-08-24 | Eli Lilly And Company | Combinatorial process for preparing substituted thiophene libraries |
US5965719A (en) * | 1996-11-15 | 1999-10-12 | Sunsorb Biotech, Inc. | Combinatorial synthesis of carbohydrate libraries |
-
2000
- 2000-10-12 EP EP00970831A patent/EP1221037A2/en not_active Withdrawn
- 2000-10-12 WO PCT/US2000/028218 patent/WO2001029537A2/en active Search and Examination
- 2000-10-12 AU AU80154/00A patent/AU8015400A/en not_active Abandoned
- 2000-10-12 JP JP2001532079A patent/JP2003512615A/en active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582809A (en) * | 1982-06-14 | 1986-04-15 | Myron J. Block | Apparatus including optical fiber for fluorescence immunoassay |
US5313264A (en) * | 1988-11-10 | 1994-05-17 | Pharmacia Biosensor Ab | Optical biosensor system |
US5565324A (en) * | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
WO1994019694A1 (en) * | 1993-02-19 | 1994-09-01 | Arris Pharmaceutical Corporation | Thin film hpmp matrix systems and methods for constructing and displaying ligands |
US5817751A (en) * | 1994-06-23 | 1998-10-06 | Affymax Technologies N.V. | Method for synthesis of diketopiperazine and diketomorpholine derivatives |
US5942387A (en) * | 1996-08-26 | 1999-08-24 | Eli Lilly And Company | Combinatorial process for preparing substituted thiophene libraries |
US5780603A (en) * | 1996-11-15 | 1998-07-14 | Synsorb Biotech, Inc. | Combinatorial synthesis of carbohydrate libraries |
US5965719A (en) * | 1996-11-15 | 1999-10-12 | Sunsorb Biotech, Inc. | Combinatorial synthesis of carbohydrate libraries |
WO1999004228A2 (en) * | 1997-07-16 | 1999-01-28 | Ljl Biosystems, Inc. | Light detection device |
Non-Patent Citations (1)
Title |
---|
BIRNBAUM S ET AL: "PEPTIDE SCREENING", CURRENT OPINION IN BIOTECHNOLOGY,GB,LONDON, vol. 3, 1992, pages 49 - 54, XP000651934, ISSN: 0958-1669 * |
Also Published As
Publication number | Publication date |
---|---|
EP1221037A2 (en) | 2002-07-10 |
AU8015400A (en) | 2001-04-30 |
WO2001029537A2 (en) | 2001-04-26 |
JP2003512615A (en) | 2003-04-02 |
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