WO2001028472A1 - Drug delivery device - Google Patents
Drug delivery device Download PDFInfo
- Publication number
- WO2001028472A1 WO2001028472A1 PCT/US2000/024983 US0024983W WO0128472A1 WO 2001028472 A1 WO2001028472 A1 WO 2001028472A1 US 0024983 W US0024983 W US 0024983W WO 0128472 A1 WO0128472 A1 WO 0128472A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug delivery
- pharmaceutically active
- active agent
- delivery device
- inner core
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00891—Glaucoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
Abstract
Description
Claims
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA02002338A MXPA02002338A (en) | 1999-10-21 | 2000-09-12 | Drug delivery device. |
AT00961836T ATE283013T1 (en) | 1999-10-21 | 2000-09-12 | MEDICATION DELIVERY DEVICE |
DE60016271T DE60016271T2 (en) | 1999-10-21 | 2000-09-12 | drug delivery |
PL355263A PL196988B1 (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
EP00961836A EP1221917B1 (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
CA002383499A CA2383499C (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
BRPI0014929-2A BR0014929B1 (en) | 1999-10-21 | 2000-09-12 | device for dispensing ophthalmic medicament. |
AU73733/00A AU768400B2 (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
DK04018677T DK1473003T3 (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
DK00961836T DK1221917T3 (en) | 2000-09-12 | 2000-09-12 | Drug delivery device |
JP2001531069A JP4837861B2 (en) | 1999-10-21 | 2000-09-12 | Drug delivery formulation |
HK02108313.1A HK1048427B (en) | 1999-10-21 | 2002-11-15 | Drug delivery device |
AU2004200908A AU2004200908B2 (en) | 1999-10-21 | 2004-03-02 | Drug delivery device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16067399P | 1999-10-21 | 1999-10-21 | |
US60/160,673 | 1999-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001028472A1 true WO2001028472A1 (en) | 2001-04-26 |
Family
ID=22577913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/024983 WO2001028472A1 (en) | 1999-10-21 | 2000-09-12 | Drug delivery device |
Country Status (22)
Country | Link |
---|---|
US (3) | US6413540B1 (en) |
EP (2) | EP1473003B1 (en) |
JP (1) | JP4837861B2 (en) |
KR (1) | KR100732262B1 (en) |
CN (1) | CN1292721C (en) |
AR (3) | AR026165A1 (en) |
AT (2) | ATE283013T1 (en) |
AU (2) | AU768400B2 (en) |
BR (1) | BR0014929B1 (en) |
CA (1) | CA2383499C (en) |
CY (1) | CY1109489T1 (en) |
DE (2) | DE60016271T2 (en) |
DK (1) | DK1473003T3 (en) |
ES (2) | ES2315598T3 (en) |
HK (2) | HK1048427B (en) |
MX (1) | MXPA02002338A (en) |
PL (1) | PL196988B1 (en) |
PT (2) | PT1473003E (en) |
TR (1) | TR200201047T2 (en) |
TW (1) | TW555575B (en) |
WO (1) | WO2001028472A1 (en) |
ZA (2) | ZA200201188B (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002089767A1 (en) * | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
EP1420716A1 (en) * | 2001-08-29 | 2004-05-26 | Ricardo A. P. De Carvalho | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
CN100349562C (en) * | 2001-07-23 | 2007-11-21 | 爱尔康公司 | Ophthalmic drug delivery device |
US7749528B2 (en) | 2001-08-29 | 2010-07-06 | Ricardo Azevedo Pontes De Carvalho | Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues |
US10449145B2 (en) | 2013-05-02 | 2019-10-22 | Retina Foundation Of The Southwest | Two-layer ocular implant |
Families Citing this family (177)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ509797A (en) * | 1998-07-10 | 2003-11-28 | Univ Sydney | Prophylactic treatments of neovascularisation in macular degeneration using a steroid |
AU767526B2 (en) | 1999-04-26 | 2003-11-13 | Gmp Vision Solutions, Inc. | Trabeculotomy device and method for treating glaucoma |
ATE283013T1 (en) * | 1999-10-21 | 2004-12-15 | Alcon Inc | MEDICATION DELIVERY DEVICE |
US7943162B2 (en) | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
US6416777B1 (en) * | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
US20020143284A1 (en) * | 2001-04-03 | 2002-10-03 | Hosheng Tu | Drug-releasing trabecular implant for glaucoma treatment |
US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
AR030345A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS |
WO2002056863A2 (en) * | 2000-12-29 | 2002-07-25 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
US6756058B2 (en) | 2001-01-03 | 2004-06-29 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with multiple agents |
WO2002053129A1 (en) * | 2001-01-03 | 2002-07-11 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
JP2004520900A (en) * | 2001-01-26 | 2004-07-15 | ボシュ・アンド・ロム・インコーポレイテッド | Improved manufacturing method of sustained release drug delivery device |
EP1418868B1 (en) | 2001-04-07 | 2008-03-26 | Glaukos Corporation | Glaucoma stent for glaucoma treatment |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US7488303B1 (en) * | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
AU2002305400A1 (en) | 2001-05-03 | 2002-11-18 | Glaukos Corporation | Medical device and methods of use for glaucoma treatment |
EP1404297B1 (en) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoir device for intraocular drug delivery |
EP1409065B1 (en) | 2001-07-23 | 2007-01-17 | Alcon, Inc. | Ophthalmic drug delivery device |
US7331984B2 (en) | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
US20060034929A1 (en) * | 2001-12-27 | 2006-02-16 | Brubaker Michael J | Sustained release drug delivery devices with prefabricated permeable plugs |
US7186232B1 (en) | 2002-03-07 | 2007-03-06 | Glaukoa Corporation | Fluid infusion methods for glaucoma treatment |
US7951155B2 (en) | 2002-03-15 | 2011-05-31 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
US9301875B2 (en) | 2002-04-08 | 2016-04-05 | Glaukos Corporation | Ocular disorder treatment implants with multiple opening |
AU2003236525A1 (en) * | 2002-06-12 | 2003-12-31 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Injection devices and methods for testing implants and for unimpeded target location testing |
US20070265582A1 (en) * | 2002-06-12 | 2007-11-15 | University Of Southern California | Injection Devices for Unimpeded Target Location Testing |
BR0313546A (en) * | 2002-08-05 | 2005-07-12 | Alcon Inc | Use of anacortave acetate to protect visual acuity in patients with age-related macular degeneration |
DE10238310A1 (en) * | 2002-08-21 | 2004-03-04 | Erich Jaeger Gmbh | electrode assembly |
US20050143363A1 (en) * | 2002-09-29 | 2005-06-30 | Innorx, Inc. | Method for subretinal administration of therapeutics including steroids; method for localizing pharmacodynamic action at the choroid of the retina; and related methods for treatment and/or prevention of retinal diseases |
WO2004073551A2 (en) * | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
JP2006518383A (en) * | 2003-02-20 | 2006-08-10 | アルコン,インコーポレイテッド | Glucocorticoid formulations for treating pathological ocular angiogenesis |
PL378210A1 (en) * | 2003-02-20 | 2006-03-20 | Alcon, Inc. | Use of steroids to treat ocular disorders |
US20050261668A1 (en) * | 2003-03-28 | 2005-11-24 | Bausch & Lomb Incorporated | Drug delivery device |
US20040236343A1 (en) * | 2003-05-23 | 2004-11-25 | Taylor Jon B. | Insertion tool for ocular implant and method for using same |
JP2007500250A (en) * | 2003-06-13 | 2007-01-11 | アルコン,インコーポレイテッド | Nonsteroidal anti-inflammatory drug formulations for treating pathological ocular angiogenesis |
EP1635842A4 (en) * | 2003-06-20 | 2007-04-04 | Alcon Inc | Treatment of amd with combination of ingredients |
US20040265356A1 (en) * | 2003-06-30 | 2004-12-30 | Bausch & Lomb Incorporated | Drug delivery device |
ZA200508654B (en) * | 2003-07-10 | 2007-01-31 | Alcon Inc | Ophthalmic drug delivery device |
JP4869930B2 (en) | 2003-08-26 | 2012-02-08 | ヴィスタ サイエンティフィック エルエルシー | Ophthalmic drug supply device |
ES2388138T3 (en) * | 2003-08-27 | 2012-10-09 | Ophthotech Corporation | Combination therapy for the treatment of ocular neovascular disorders |
AU2004274026A1 (en) * | 2003-09-18 | 2005-03-31 | Macusight, Inc. | Transscleral delivery |
US20050136095A1 (en) * | 2003-12-22 | 2005-06-23 | Brian Levy | Drug delivery device with suture ring |
US20050158365A1 (en) * | 2003-12-22 | 2005-07-21 | David Watson | Drug delivery device with mechanical locking mechanism |
US7276050B2 (en) * | 2004-03-02 | 2007-10-02 | Alan Franklin | Trans-scleral drug delivery method and apparatus |
US9549895B2 (en) * | 2004-04-23 | 2017-01-24 | Massachusetts Eye And Ear Infirmary | Methods and compositions for preserving the viability of photoreceptor cells |
US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
US8673341B2 (en) * | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
US20060182781A1 (en) * | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Methods for treating ocular conditions with cyclic lipid contraining microparticles |
US7589057B2 (en) | 2004-04-30 | 2009-09-15 | Allergan, Inc. | Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems |
US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
US20060024350A1 (en) * | 2004-06-24 | 2006-02-02 | Varner Signe E | Biodegradable ocular devices, methods and systems |
US20060110428A1 (en) * | 2004-07-02 | 2006-05-25 | Eugene Dejuan | Methods and devices for the treatment of ocular conditions |
WO2006039459A1 (en) * | 2004-09-30 | 2006-04-13 | Bausch & Lomb Incorporated | Capsule for encasing tablets for surgical insertion into the human body |
US20060134162A1 (en) * | 2004-12-16 | 2006-06-22 | Larson Christopher W | Methods for fabricating a drug delivery device |
US20060134176A1 (en) * | 2004-12-22 | 2006-06-22 | Bausch & Lomb Incorporated | Pharmaceutical delivery system and method of use |
KR101387456B1 (en) | 2005-02-09 | 2014-04-21 | 산텐 세이야꾸 가부시키가이샤 | Liquid formulations for treatment of diseases or conditions |
US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
WO2006110487A1 (en) * | 2005-04-08 | 2006-10-19 | Surmodics, Inc. | Sustained release implants for subretinal delivery |
PL1919290T3 (en) * | 2005-07-12 | 2014-06-30 | Ampio Pharmaceuticals Inc | Methods and products for treatment of diseases |
US20100003297A1 (en) * | 2005-08-11 | 2010-01-07 | Massachusetts Institute Of Technology | Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues |
US20070100199A1 (en) * | 2005-11-03 | 2007-05-03 | Lilip Lau | Apparatus and method of delivering biomaterial to the heart |
US20070212397A1 (en) * | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
WO2007047626A1 (en) * | 2005-10-14 | 2007-04-26 | Alcon, Inc. | Combination treatment with anecortave acetate and bevacizumab or ranibizumab for pathologic ocular angiogenesis |
EP2001438A2 (en) | 2006-02-09 | 2008-12-17 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
DK2001466T3 (en) | 2006-03-23 | 2016-02-29 | Santen Pharmaceutical Co Ltd | LOW-DOSAGE RAPAMYCINE FOR TREATMENT OF VASCULAR PERMEABILITY-RELATED DISEASES |
KR20110038144A (en) * | 2006-03-31 | 2011-04-13 | 큐엘티 플러그 딜리버리, 인코포레이티드 | Drug delivery methods, structures, and compositions for nasolacrimal system |
US20070293807A1 (en) * | 2006-05-01 | 2007-12-20 | Lynch Mary G | Dual drainage pathway shunt device and method for treating glaucoma |
JP4829345B2 (en) * | 2006-05-04 | 2011-12-07 | カフマン、ハーバート | Methods, devices, and systems for administering therapeutic agents to the eye |
US7981096B2 (en) * | 2006-05-12 | 2011-07-19 | David Castillejos | Optic nerve head implant and medication delivery system |
SG138567A1 (en) * | 2006-06-21 | 2008-01-28 | Johnson & Johnson Vision Care | Punctal plugs for the delivery of active agents |
US8852256B2 (en) | 2010-11-15 | 2014-10-07 | Aquesys, Inc. | Methods for intraocular shunt placement |
US8663303B2 (en) | 2010-11-15 | 2014-03-04 | Aquesys, Inc. | Methods for deploying an intraocular shunt from a deployment device and into an eye |
US10085884B2 (en) | 2006-06-30 | 2018-10-02 | Aquesys, Inc. | Intraocular devices |
US8308701B2 (en) | 2010-11-15 | 2012-11-13 | Aquesys, Inc. | Methods for deploying intraocular shunts |
US8721702B2 (en) | 2010-11-15 | 2014-05-13 | Aquesys, Inc. | Intraocular shunt deployment devices |
US20120123316A1 (en) | 2010-11-15 | 2012-05-17 | Aquesys, Inc. | Intraocular shunts for placement in the intra-tenon's space |
EP2043572B1 (en) | 2006-06-30 | 2014-12-31 | Aquesys Inc. | Apparatus for relieving pressure in an organ |
US8506515B2 (en) | 2006-11-10 | 2013-08-13 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
US20100034808A1 (en) * | 2006-11-21 | 2010-02-11 | Toru Nakazawa | Compositions and methods for preserving cells of the eye |
US20080140024A1 (en) * | 2006-12-08 | 2008-06-12 | Yoseph Yaacobi | Drug delivery device |
WO2008076544A2 (en) * | 2006-12-18 | 2008-06-26 | Alcon Research, Ltd. | Devices and methods for ophthalmic drug delivery |
US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
US20100104654A1 (en) * | 2008-10-27 | 2010-04-29 | Allergan, Inc. | Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
PL2391419T3 (en) | 2009-01-29 | 2019-12-31 | Forsight Vision4, Inc. | Posterior segment drug delivery |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
ES2921527T3 (en) | 2009-06-03 | 2022-08-29 | Forsight Vision5 Inc | Anterior segment drug delivery |
DE202010017530U1 (en) | 2009-06-22 | 2012-03-28 | Dmi Acquisition Corp. | Danazol compound for the treatment of diseases |
CA2765883A1 (en) * | 2009-06-22 | 2010-12-29 | Dmi Acquisition Corp. | Methods and products for treatment of diseases |
US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
JP2013523821A (en) * | 2010-04-06 | 2013-06-17 | アラーガン、インコーポレイテッド | Sustained release reservoir implant for intra-anterior drug delivery |
WO2011133964A2 (en) | 2010-04-23 | 2011-10-27 | Massachusetts Eye And Ear Infirmary | Methods and compositions for preserving photoreceptor and retinal pigment epithelial cells |
WO2011146483A1 (en) | 2010-05-17 | 2011-11-24 | Aerie Pharmaceuticals, Inc. | Drug delivery devices for delivery of ocular therapeutic agents |
EP3861969A1 (en) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injector apparatus for drug delivery |
SI2600812T1 (en) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Apparatus to treat an eye |
WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
US20120109054A1 (en) * | 2010-10-29 | 2012-05-03 | Vista Scientific Llc | Devices with an erodible surface for delivering at least one active agent to tissue over a prolonged period of time |
WO2012061045A2 (en) | 2010-11-01 | 2012-05-10 | Massachusetts Eye And Ear Infirmary | Methods and compositions for preserving retinal ganglion cells |
US10842671B2 (en) | 2010-11-15 | 2020-11-24 | Aquesys, Inc. | Intraocular shunt placement in the suprachoroidal space |
CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
US9107816B2 (en) * | 2011-02-04 | 2015-08-18 | Taris Biomedical Llc | Implantable device for controlled dissolution and diffusion of low solubility drug |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
US20150005254A1 (en) | 2011-06-27 | 2015-01-01 | Massachusetts Eye And Ear Infirmary | Methods for treating ocular inflammatory disorders |
EP4249059A3 (en) | 2011-06-28 | 2023-11-29 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
US9724357B2 (en) | 2011-08-15 | 2017-08-08 | Massachusetts Eye & Ear Infirmary | Methods for preserving photoreceptor cell viability following retinal detachment |
EP3659495B1 (en) | 2011-09-13 | 2022-12-14 | Dose Medical Corporation | Intraocular physiological sensor |
WO2013040238A2 (en) | 2011-09-13 | 2013-03-21 | Vista Scientific Llc | Sustained release ocular drug delivery devices and methods of manufacture |
RU2740680C2 (en) | 2011-09-14 | 2021-01-19 | Форсайт Вижн5, Инк. | Eye inserter device and methods |
SI2755600T1 (en) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Fluid exchange apparatus |
CA2888805C (en) | 2011-10-21 | 2020-07-14 | Massachusetts Eye And Ear Infirmary | Methods and compositions for promoting axon regeneration and nerve function |
US9610195B2 (en) | 2013-02-27 | 2017-04-04 | Aquesys, Inc. | Intraocular shunt implantation methods and devices |
US9808373B2 (en) | 2013-06-28 | 2017-11-07 | Aquesys, Inc. | Intraocular shunt implantation |
US8765210B2 (en) | 2011-12-08 | 2014-07-01 | Aquesys, Inc. | Systems and methods for making gelatin shunts |
US8852136B2 (en) * | 2011-12-08 | 2014-10-07 | Aquesys, Inc. | Methods for placing a shunt into the intra-scleral space |
US10080682B2 (en) | 2011-12-08 | 2018-09-25 | Aquesys, Inc. | Intrascleral shunt placement |
US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
EP2708209A1 (en) * | 2012-09-13 | 2014-03-19 | AJL Ophthalmic, S.A. | Scleral epimacular implant |
PT2911623T (en) | 2012-10-26 | 2019-11-21 | Forsight Vision5 Inc | Ophthalmic system for sustained release of drug to eye |
EP2914225B1 (en) * | 2012-11-01 | 2021-02-17 | Poway Retinal Technologies LLC | Retinal repair device |
KR20150105355A (en) | 2012-12-19 | 2015-09-16 | 앰피오 파마슈티컬스 인코퍼레이티드 | Method for treatment of diseases |
US9745558B2 (en) | 2013-02-18 | 2017-08-29 | Vegenics Pty Limited | VEGFR-3 ligand binding molecules and uses thereof |
US10159600B2 (en) | 2013-02-19 | 2018-12-25 | Aquesys, Inc. | Adjustable intraocular flow regulation |
TW201507749A (en) | 2013-03-11 | 2015-03-01 | Sanofi Aventis Deutschland | Assembly for a drug delivery device |
US9730638B2 (en) | 2013-03-13 | 2017-08-15 | Glaukos Corporation | Intraocular physiological sensor |
AU2014236455B2 (en) | 2013-03-14 | 2018-07-12 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
EP4302736A3 (en) | 2013-03-28 | 2024-04-03 | ForSight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
CN105431204A (en) | 2013-07-12 | 2016-03-23 | 奥普索特克公司 | Methods for treating or preventing ophthalmological conditions |
DK3066201T3 (en) | 2013-11-07 | 2018-06-06 | Editas Medicine Inc | CRISPR-RELATED PROCEDURES AND COMPOSITIONS WITH LEADING GRADES |
BR122020011777B1 (en) | 2013-11-14 | 2022-01-25 | AqueSys, Inc | Insertion device for the treatment of glaucoma |
EP3089748A4 (en) | 2014-01-02 | 2017-09-27 | Massachusetts Eye & Ear Infirmary | Treating ocular neovascularization |
EP3114227B1 (en) | 2014-03-05 | 2021-07-21 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating usher syndrome and retinitis pigmentosa |
US11141493B2 (en) | 2014-03-10 | 2021-10-12 | Editas Medicine, Inc. | Compositions and methods for treating CEP290-associated disease |
US11339437B2 (en) | 2014-03-10 | 2022-05-24 | Editas Medicine, Inc. | Compositions and methods for treating CEP290-associated disease |
EP3553176A1 (en) | 2014-03-10 | 2019-10-16 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating leber's congenital amaurosis 10 (lca10) |
EP3981876A1 (en) | 2014-03-26 | 2022-04-13 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating sickle cell disease |
AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
US10258503B2 (en) | 2014-07-15 | 2019-04-16 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
MY182793A (en) | 2014-08-08 | 2021-02-05 | Forsight Vision4 Inc | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
US10500091B2 (en) | 2014-11-10 | 2019-12-10 | Forsight Vision4, Inc. | Expandable drug delivery devices and methods of use |
EP3283004A4 (en) | 2015-04-13 | 2018-12-05 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
AU2016253150B2 (en) | 2015-04-24 | 2022-04-21 | Editas Medicine, Inc. | Evaluation of Cas9 molecule/guide RNA molecule complexes |
WO2016187426A1 (en) | 2015-05-19 | 2016-11-24 | Amorphex Therapeutics Llc | A device that delivers a sustained low-dose of a myopia-suppressing drug |
NZ737997A (en) | 2015-06-03 | 2019-03-29 | Aquesys Inc | Ab externo intraocular shunt placement |
US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
CN109312338B (en) | 2015-10-30 | 2022-09-27 | 爱迪塔斯医药公司 | CRISPR/CAS related methods and compositions for treating herpes simplex virus |
CN108430405B (en) | 2015-11-20 | 2021-04-13 | 弗赛特影像4股份有限公司 | Porous structures for sustained release drug delivery devices |
EP3433364A1 (en) | 2016-03-25 | 2019-01-30 | Editas Medicine, Inc. | Systems and methods for treating alpha 1-antitrypsin (a1at) deficiency |
US11617680B2 (en) | 2016-04-05 | 2023-04-04 | Forsight Vision4, Inc. | Implantable ocular drug delivery devices |
AU2017252294B2 (en) | 2016-04-20 | 2021-12-02 | Dose Medical Corporation | Bioresorbable ocular drug delivery device |
BR112018074389A2 (en) | 2016-06-02 | 2019-03-06 | Aquesys, Inc. | intraocular drug shipment |
BR112019001887A2 (en) | 2016-08-02 | 2019-07-09 | Editas Medicine Inc | compositions and methods for treating cep290-associated disease |
CA3032153A1 (en) | 2016-08-19 | 2018-02-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (serms) confer protection against photoreceptor degeneration |
EP3532616A1 (en) | 2016-10-28 | 2019-09-04 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating herpes simplex virus |
JP2020514407A (en) | 2017-01-24 | 2020-05-21 | マクリーゲン, インク.Macregen, Inc. | Treatment of age-related macular degeneration and other eye diseases using apolipoprotein mimetics |
WO2018161035A1 (en) | 2017-03-03 | 2018-09-07 | Macregen, Inc. | Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents |
WO2018170184A1 (en) | 2017-03-14 | 2018-09-20 | Editas Medicine, Inc. | Systems and methods for the treatment of hemoglobinopathies |
WO2018204848A1 (en) | 2017-05-05 | 2018-11-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Ocular applications of matrix bound vesicles (mbvs) |
EP3622070A2 (en) | 2017-05-10 | 2020-03-18 | Editas Medicine, Inc. | Crispr/rna-guided nuclease systems and methods |
WO2019018350A1 (en) | 2017-07-17 | 2019-01-24 | Keith Roizman | Topical delivery of therapeutic agents comprising cell-penetrating peptides for use for the treatment of age-related macular degeneration and other eye diseases |
US11246753B2 (en) | 2017-11-08 | 2022-02-15 | Aquesys, Inc. | Manually adjustable intraocular flow regulation |
WO2019103906A1 (en) | 2017-11-21 | 2019-05-31 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
EP3758736B1 (en) | 2018-03-02 | 2024-05-01 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Il-34 for use in a method of treating retinal inflammation and neurodegeneration |
US11135089B2 (en) | 2018-03-09 | 2021-10-05 | Aquesys, Inc. | Intraocular shunt inserter |
US10952898B2 (en) | 2018-03-09 | 2021-03-23 | Aquesys, Inc. | Intraocular shunt inserter |
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AU2021300425A1 (en) | 2020-07-02 | 2023-02-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cyclic compounds for use in treating retinal degeneration |
WO2022221741A1 (en) | 2021-04-16 | 2022-10-20 | Editas Medicine, Inc. | Crispr/rna-guided nuclease-related methods and compositions for treating rho-associated autosomal-dominant retinitis pigmentosa (adrp) |
CN115737892A (en) * | 2022-11-21 | 2023-03-07 | 诺莱生物医学科技有限公司 | Elastic dressing carrying repair matrix and preparation method thereof |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4022553A1 (en) * | 1990-07-16 | 1992-01-23 | Hund Helmut Gmbh | Medical contact lens - with recess contg. therapeutically or diagnostically active substance |
US5403901A (en) | 1990-11-07 | 1995-04-04 | Nestle S.A. | Flexible, high refractive index polymers |
US5476511A (en) | 1992-05-04 | 1995-12-19 | Allergan, Inc. | Subconjunctival implants for ocular drug delivery |
WO1997014415A1 (en) * | 1995-10-19 | 1997-04-24 | F.H. Faulding & Co. Limited | Analgesic immediate and controlled release pharmaceutical composition |
US5679666A (en) | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
WO1998023228A1 (en) * | 1996-11-25 | 1998-06-04 | Alza Corporation | Directional drug delivery stent |
US5770592A (en) | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
WO1998043611A1 (en) * | 1997-03-31 | 1998-10-08 | Alza Corporation | Diffusional implantable delivery system |
US5824073A (en) | 1996-03-18 | 1998-10-20 | Peyman; Gholam A. | Macular indentor for use in the treatment of subretinal neovascular membranes |
US5824072A (en) | 1993-11-15 | 1998-10-20 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3416530A (en) | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
US3828777A (en) | 1971-11-08 | 1974-08-13 | Alza Corp | Microporous ocular device |
US4014725A (en) * | 1975-03-27 | 1977-03-29 | Union Carbide Corporation | Method of making carbon cloth from pitch based fiber |
US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
US4300557A (en) | 1980-01-07 | 1981-11-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating intraocular malignancies |
US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US5322691A (en) | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
US5147647A (en) | 1986-10-02 | 1992-09-15 | Sohrab Darougar | Ocular insert for the fornix |
US4759746A (en) * | 1987-05-14 | 1988-07-26 | Straus Jeffrey G | Retro-bulbar needle |
US4997652A (en) | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
US4853224A (en) | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
DE3905050A1 (en) | 1989-02-18 | 1990-08-30 | Lohmann Therapie Syst Lts | THERAPEUTIC SYSTEM FOR DELAYED AND CONTROLLED TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE SUBSTANCES (II) |
US4946450A (en) | 1989-04-18 | 1990-08-07 | Biosource Genetics Corporation | Glucan/collagen therapeutic eye shields |
US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
FR2690846B1 (en) | 1992-05-05 | 1995-07-07 | Aiache Jean Marc | GALENIC FORM FOR EYE ADMINISTRATION AND METHOD OF PREPARATION. |
WO1994005257A1 (en) | 1992-09-08 | 1994-03-17 | Allergan, Inc. | Sustained release of ophthalmic drugs from a soluble polymer drug delivery vehicle |
WO1995003009A1 (en) | 1993-07-22 | 1995-02-02 | Oculex Pharmaceuticals, Inc. | Method of treatment of macular degeneration |
US5516522A (en) | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
JPH09511507A (en) | 1994-04-04 | 1997-11-18 | フリーマン,ウイリアム・アール | Use of phosphonyl methoxyalkyl nucleosides to treat elevated intraocular pressure |
US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
US5710165A (en) | 1994-07-06 | 1998-01-20 | Synthelabo | Use of polyamine antagonists for the treatment of glaucoma |
CN2219115Y (en) * | 1994-08-31 | 1996-02-07 | 程康 | Pulse medicine therapeutic apparatus for myopia |
AUPM897594A0 (en) | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
AU708529B2 (en) | 1994-11-10 | 1999-08-05 | University Of Kentucky Research Foundation, The | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
CN1283324C (en) | 1995-05-14 | 2006-11-08 | 奥普通诺尔有限公司 | Intraocular implant, delivery device, and method of implantation |
WO1997018812A1 (en) * | 1995-11-17 | 1997-05-29 | Alcon Laboratories, Inc. | Combination therapy for treating glaucoma |
US5743274A (en) | 1996-03-18 | 1998-04-28 | Peyman; Gholam A. | Macular bandage for use in the treatment of subretinal neovascular members |
US5904144A (en) * | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
JP3309175B2 (en) | 1996-03-25 | 2002-07-29 | 参天製薬株式会社 | Scleral plug containing proteinaceous drug |
US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US6120460A (en) * | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
ES2232005T3 (en) | 1997-08-11 | 2005-05-16 | Allergan, Inc. | BIODEGRADABLE STERILE IMPLANT DEVICE CONTAINING RETINOID WITH IMPROVED BIOCOMPATIBILITY AND PREPARATION METHOD. |
US5902598A (en) | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6066671A (en) | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
EP1061913B1 (en) | 1998-03-13 | 2007-06-27 | The Johns Hopkins University School Of Medicine | The use of a protein tyrosine inhibitor such as genistein in the treatment of diabetic retinopathy |
DE19847192A1 (en) | 1998-10-13 | 2000-04-27 | Wella Ag | Colorant for fibers, especially human hair, contains 4-nitrophenyl-N-heterocyclic, -cycloalkane, -alkoxyalkane or -amine compound |
US6146366A (en) | 1998-11-03 | 2000-11-14 | Ras Holding Corp | Device for the treatment of macular degeneration and other eye disorders |
US6399655B1 (en) | 1998-12-22 | 2002-06-04 | Johns Hopkins University, School Of Medicine | Method for the prophylactic treatment of cataracts |
US6217895B1 (en) | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
ATE283013T1 (en) * | 1999-10-21 | 2004-12-15 | Alcon Inc | MEDICATION DELIVERY DEVICE |
-
2000
- 2000-09-12 AT AT00961836T patent/ATE283013T1/en active
- 2000-09-12 CN CNB008131864A patent/CN1292721C/en not_active Expired - Fee Related
- 2000-09-12 PL PL355263A patent/PL196988B1/en not_active IP Right Cessation
- 2000-09-12 DE DE60016271T patent/DE60016271T2/en not_active Expired - Lifetime
- 2000-09-12 MX MXPA02002338A patent/MXPA02002338A/en active IP Right Grant
- 2000-09-12 ES ES04018677T patent/ES2315598T3/en not_active Expired - Lifetime
- 2000-09-12 AU AU73733/00A patent/AU768400B2/en not_active Ceased
- 2000-09-12 TR TR2002/01047T patent/TR200201047T2/en unknown
- 2000-09-12 EP EP04018677A patent/EP1473003B1/en not_active Expired - Lifetime
- 2000-09-12 DE DE60040876T patent/DE60040876D1/en not_active Expired - Lifetime
- 2000-09-12 AT AT04018677T patent/ATE414494T1/en active
- 2000-09-12 CA CA002383499A patent/CA2383499C/en not_active Expired - Fee Related
- 2000-09-12 BR BRPI0014929-2A patent/BR0014929B1/en not_active IP Right Cessation
- 2000-09-12 WO PCT/US2000/024983 patent/WO2001028472A1/en active IP Right Grant
- 2000-09-12 JP JP2001531069A patent/JP4837861B2/en not_active Expired - Fee Related
- 2000-09-12 EP EP00961836A patent/EP1221917B1/en not_active Expired - Lifetime
- 2000-09-12 KR KR1020027005020A patent/KR100732262B1/en not_active IP Right Cessation
- 2000-09-12 ES ES00961836T patent/ES2231257T3/en not_active Expired - Lifetime
- 2000-09-12 US US09/660,000 patent/US6413540B1/en not_active Expired - Lifetime
- 2000-09-12 DK DK04018677T patent/DK1473003T3/en active
- 2000-09-12 PT PT04018677T patent/PT1473003E/en unknown
- 2000-09-12 PT PT00961836T patent/PT1221917E/en unknown
- 2000-10-03 AR ARP000105210A patent/AR026165A1/en active IP Right Grant
- 2000-10-05 TW TW089120788A patent/TW555575B/en not_active IP Right Cessation
-
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- 2002-02-12 ZA ZA200201188A patent/ZA200201188B/en unknown
- 2002-02-12 ZA ZA200201189A patent/ZA200201189B/en unknown
- 2002-07-01 US US10/186,960 patent/US6808719B2/en not_active Expired - Lifetime
- 2002-11-15 HK HK02108313.1A patent/HK1048427B/en not_active IP Right Cessation
-
2003
- 2003-03-25 AR ARP030101035A patent/AR039132A2/en unknown
- 2003-03-25 AR ARP030101034A patent/AR039131A2/en unknown
-
2004
- 2004-03-02 AU AU2004200908A patent/AU2004200908B2/en not_active Ceased
- 2004-10-04 US US10/957,910 patent/US20050112175A1/en not_active Abandoned
-
2005
- 2005-03-08 HK HK05102024.1A patent/HK1072177A1/en not_active IP Right Cessation
-
2009
- 2009-01-22 CY CY20091100083T patent/CY1109489T1/en unknown
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4022553A1 (en) * | 1990-07-16 | 1992-01-23 | Hund Helmut Gmbh | Medical contact lens - with recess contg. therapeutically or diagnostically active substance |
US5403901A (en) | 1990-11-07 | 1995-04-04 | Nestle S.A. | Flexible, high refractive index polymers |
US5679666A (en) | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
US5770592A (en) | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
US5476511A (en) | 1992-05-04 | 1995-12-19 | Allergan, Inc. | Subconjunctival implants for ocular drug delivery |
US5824072A (en) | 1993-11-15 | 1998-10-20 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
WO1997014415A1 (en) * | 1995-10-19 | 1997-04-24 | F.H. Faulding & Co. Limited | Analgesic immediate and controlled release pharmaceutical composition |
US5824073A (en) | 1996-03-18 | 1998-10-20 | Peyman; Gholam A. | Macular indentor for use in the treatment of subretinal neovascular membranes |
WO1998023228A1 (en) * | 1996-11-25 | 1998-06-04 | Alza Corporation | Directional drug delivery stent |
WO1998043611A1 (en) * | 1997-03-31 | 1998-10-08 | Alza Corporation | Diffusional implantable delivery system |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002089767A1 (en) * | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
CN100349562C (en) * | 2001-07-23 | 2007-11-21 | 爱尔康公司 | Ophthalmic drug delivery device |
EP1420716A1 (en) * | 2001-08-29 | 2004-05-26 | Ricardo A. P. De Carvalho | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
US7749528B2 (en) | 2001-08-29 | 2010-07-06 | Ricardo Azevedo Pontes De Carvalho | Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues |
EP1420716A4 (en) * | 2001-08-29 | 2010-10-27 | Carvalho Ricardo A P De | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
EP1420716B1 (en) * | 2001-08-29 | 2012-08-15 | Ricardo A. P. De Carvalho | An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues |
US10449145B2 (en) | 2013-05-02 | 2019-10-22 | Retina Foundation Of The Southwest | Two-layer ocular implant |
US10881609B2 (en) | 2013-05-02 | 2021-01-05 | Retina Foundation Of The Southwest | Methods for treating eye disorders using ocular implants |
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