WO2000079285A3 - Devices and methods for the performance of miniaturized homogeneous assays - Google Patents
Devices and methods for the performance of miniaturized homogeneous assays Download PDFInfo
- Publication number
- WO2000079285A3 WO2000079285A3 PCT/US2000/016653 US0016653W WO0079285A3 WO 2000079285 A3 WO2000079285 A3 WO 2000079285A3 US 0016653 W US0016653 W US 0016653W WO 0079285 A3 WO0079285 A3 WO 0079285A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- platform
- miniaturized
- performance
- devices
- Prior art date
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
- B01F25/23—Mixing by intersecting jets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00421—Means for dispensing and evacuation of reagents using centrifugation
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- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00488—Means for mixing reactants or products in the reaction vessels by rotation of the reaction vessels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00536—Sheets in the shape of disks
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2200/02—Adapting objects or devices to another
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
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- G—PHYSICS
- G01—MEASURING; TESTING
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10T436/00—Chemistry: analytical and immunological testing
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
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- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT00939944T ATE272213T1 (en) | 1999-06-18 | 2000-06-16 | DEVICES AND METHODS FOR PERFORMING MINIATURIZED HOMOGENEOUS TESTS |
JP2001505200A JP2004529312A (en) | 1999-06-18 | 2000-06-16 | Devices and methods for miniaturized homogeneous assays |
AU54949/00A AU5494900A (en) | 1999-06-18 | 2000-06-16 | Devices and methods for the performance of miniaturized homogeneous assays |
EP00939944A EP1230544B1 (en) | 1999-06-18 | 2000-06-16 | Devices and methods for the performance of miniaturized homogeneous assays |
DE60012562T DE60012562D1 (en) | 1999-06-18 | 2000-06-16 | DEVICES AND METHOD FOR CARRYING OUT MINIATURIZED HOMOGENEOUS TESTS |
JP2001583935A JP2004501360A (en) | 2000-05-15 | 2001-05-15 | Microfluidic devices and methods for high-throughput screening |
AU2001263162A AU2001263162A1 (en) | 2000-05-15 | 2001-05-15 | Microfluidics devices and methods for high throughput screening |
EP01937420A EP1284819A2 (en) | 2000-05-15 | 2001-05-15 | Microfluidics devices and methods for high throughput screening |
PCT/US2001/015743 WO2001087485A2 (en) | 2000-05-15 | 2001-05-15 | Microfluidics devices and methods for high throughput screening |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14010599P | 1999-06-18 | 1999-06-18 | |
US60/140,105 | 1999-06-18 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000079285A2 WO2000079285A2 (en) | 2000-12-28 |
WO2000079285A3 true WO2000079285A3 (en) | 2002-06-20 |
WO2000079285A9 WO2000079285A9 (en) | 2002-10-03 |
Family
ID=22489780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/016653 WO2000079285A2 (en) | 1999-06-18 | 2000-06-16 | Devices and methods for the performance of miniaturized homogeneous assays |
Country Status (7)
Country | Link |
---|---|
US (2) | US6582662B1 (en) |
EP (1) | EP1230544B1 (en) |
JP (1) | JP2004529312A (en) |
AT (1) | ATE272213T1 (en) |
AU (1) | AU5494900A (en) |
DE (1) | DE60012562D1 (en) |
WO (1) | WO2000079285A2 (en) |
Cited By (2)
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US7939018B2 (en) | 2000-06-28 | 2011-05-10 | 3M Innovative Properties Company | Multi-format sample processing devices and systems |
US8003051B2 (en) | 2001-12-28 | 2011-08-23 | 3M Innovative Properties Company | Thermal structure for sample processing systems |
Families Citing this family (108)
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FR2790684B1 (en) * | 1999-03-09 | 2001-05-11 | Biomerieux Sa | APPARATUS FOR CAPILLARITY TRANSFER OF LIQUIDS |
EP1230544B1 (en) * | 1999-06-18 | 2004-07-28 | Gamera Bioscience Corporation | Devices and methods for the performance of miniaturized homogeneous assays |
US20020151078A1 (en) * | 2000-05-15 | 2002-10-17 | Kellogg Gregory J. | Microfluidics devices and methods for high throughput screening |
US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
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US7026131B2 (en) * | 2000-11-17 | 2006-04-11 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-discs |
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
WO2004058405A1 (en) * | 2001-05-02 | 2004-07-15 | 3M Innovative Properties Company | Sample processing device with resealable process chamber |
US20020168292A1 (en) * | 2001-05-14 | 2002-11-14 | Whisenhunt Donald Wayne | Systems and methods for the high throughput preparation and analysis of chemical reactions |
WO2003001391A1 (en) * | 2001-06-21 | 2003-01-03 | Bell Robert A | Method and apparatus for spatially coordinating, storing and manipulating computer aided design drawings |
US6919058B2 (en) | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
SE0104077D0 (en) * | 2001-10-21 | 2001-12-05 | Gyros Ab | A method and instrumentation for micro dispensation of droplets |
AT500669B1 (en) * | 2001-09-24 | 2007-02-15 | Oesterr Forsch Seibersdorf | SOLID CARRIER FOR THE IMMOBILIZATION OF BIOMOLECULES |
US7244393B2 (en) | 2001-12-21 | 2007-07-17 | Kimberly-Clark Worldwide, Inc. | Diagnostic device and system |
CA2471018A1 (en) * | 2002-01-28 | 2003-08-07 | Burstein Technologies, Inc. | Methods and apparatus for logical triggering of an optical bio-disc |
AU2003209372B2 (en) | 2002-01-31 | 2009-02-19 | Burstein Technologies, Inc. | Method for triggering through disc grooves and related optical analysis discs and system |
US20040241381A1 (en) * | 2002-01-31 | 2004-12-02 | Chen Yihfar | Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs |
US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
JP4194787B2 (en) * | 2002-03-14 | 2008-12-10 | パナソニック株式会社 | Analysis device and analysis disk used for it |
WO2003087779A1 (en) | 2002-04-08 | 2003-10-23 | Gyros Ab | Homing process |
US7005265B1 (en) | 2002-06-20 | 2006-02-28 | Wenhong Fan | Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays |
US7083974B2 (en) | 2002-07-12 | 2006-08-01 | Applera Corporation | Rotatable sample disk and method of loading a sample disk |
EP1391237B1 (en) * | 2002-08-01 | 2011-09-21 | Tosoh Corporation | Fine channel device, desksize chemical plant and fine particle producing apparatus employing them |
US7094354B2 (en) * | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
WO2004058406A2 (en) * | 2002-12-24 | 2004-07-15 | Tecan Trading Ag | Microfluidics devices and methods for diluting samples and reagents |
US7332129B2 (en) | 2003-01-09 | 2008-02-19 | 3M Innovative Properties Company | Sample processing device having process chambers with bypass slots |
EP1594798B1 (en) | 2003-01-30 | 2018-12-19 | Gyros Patent Ab | Inner walls of microfluidic devices |
SE0300822D0 (en) | 2003-03-23 | 2003-03-23 | Gyros Ab | A collection of Micro Scale Devices |
SE0300823D0 (en) | 2003-03-23 | 2003-03-23 | Gyros Ab | Preloaded Microscale Devices |
JP2004309145A (en) * | 2003-04-02 | 2004-11-04 | Hitachi High-Technologies Corp | Chemical analysis device and structure for chemical analysis |
WO2004089546A2 (en) * | 2003-04-04 | 2004-10-21 | Tecan Trading Ag | Elastomeric tools for fabricating of polymeric devices and uses thereof |
US7435381B2 (en) * | 2003-05-29 | 2008-10-14 | Siemens Healthcare Diagnostics Inc. | Packaging of microfluidic devices |
US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
US20050130177A1 (en) | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7322254B2 (en) * | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7837947B2 (en) * | 2003-12-12 | 2010-11-23 | 3M Innovative Properties Company | Sample mixing on a microfluidic device |
US20050142571A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using solid phase material |
US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
US20050142570A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent |
EP1712916A4 (en) * | 2003-12-26 | 2008-07-23 | Matsushita Electric Ind Co Ltd | Biological sample discrimination apparatus, biological sample discrimination method, and biological sample discrimination plate |
US8592219B2 (en) * | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
SE0400181D0 (en) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
JP2005257337A (en) * | 2004-03-09 | 2005-09-22 | Brother Ind Ltd | Inspection object receiver, inspection device, and inspection method |
US20050227350A1 (en) * | 2004-04-13 | 2005-10-13 | Agency For Science, Technology And Research | Device and method for studying cell migration and deformation |
US7758814B2 (en) * | 2004-06-05 | 2010-07-20 | Freeslate, Inc. | Microfluidic fluid distribution manifold for use with multi-channel reactor systems |
EP1838723A4 (en) * | 2004-06-29 | 2008-10-08 | Univ Cincinnati | Polymorphisms and haplotypes of the alpha 2c adrenergic receptor gene |
WO2006009506A1 (en) * | 2004-07-16 | 2006-01-26 | Gyros Patent Ab | Sequential method |
US8097225B2 (en) * | 2004-07-28 | 2012-01-17 | Honeywell International Inc. | Microfluidic cartridge with reservoirs for increased shelf life of installed reagents |
DE102004046396A1 (en) | 2004-09-24 | 2006-04-13 | Land Baden-Württemberg, vertreten durch das Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg, vertreten durch den Minister | A particle sedimentation apparatus and method for performing a particle sedimentation |
US7608160B2 (en) * | 2004-10-13 | 2009-10-27 | Rheonix, Inc. | Laminated microfluidic structures and method for making |
US7832429B2 (en) * | 2004-10-13 | 2010-11-16 | Rheonix, Inc. | Microfluidic pump and valve structures and fabrication methods |
EP1849005A1 (en) | 2005-01-17 | 2007-10-31 | Gyros Patent Ab | A method for detecting an at least bivalent analyte using two affinity reactants |
JP4693657B2 (en) * | 2005-03-29 | 2011-06-01 | シチズンホールディングス株式会社 | Biosensor |
US7754151B2 (en) | 2005-04-04 | 2010-07-13 | Panasonic Corporation | Liquid homogenizer and analyzer employing the same |
JP4837725B2 (en) * | 2005-04-09 | 2011-12-14 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | Sample liquid inspection apparatus and method |
EP1874677B1 (en) * | 2005-04-14 | 2013-03-20 | Gyros Patent Ab | Microfluidic device with meander |
EP1874469A4 (en) | 2005-04-14 | 2014-02-26 | Gyros Patent Ab | A microfluidic device with finger valves |
EP1874470A1 (en) * | 2005-04-14 | 2008-01-09 | Gyros Patent Ab | Microfluidic device with serial valve |
JP5139263B2 (en) | 2005-04-14 | 2013-02-06 | ギロス・パテント・エービー | Liquid plug |
US7763210B2 (en) | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
US7323660B2 (en) * | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
DE102005031920B4 (en) * | 2005-07-07 | 2007-12-20 | Isotopen Technologien München AG | Apparatus and method for producing a small amount of a radioactive compound |
US7731910B2 (en) * | 2005-08-05 | 2010-06-08 | Hewlett-Packard Development Company, L.P. | Microfluidic mixing assembly |
WO2007069940A1 (en) | 2005-12-12 | 2007-06-21 | Gyros Patent Ab | Microfluidic assays and microfluidic devices |
TWI272464B (en) * | 2006-03-01 | 2007-02-01 | Instr Technology Res Ct Nat Ap | Fluid order controlling apparatus and method |
US7651869B2 (en) * | 2006-03-14 | 2010-01-26 | Research International, Inc. | Optical assay apparatus and methods |
TW200840641A (en) * | 2007-04-03 | 2008-10-16 | Univ Nat Taiwan | Disk-shaped concentration regulation flow channel structure |
JPWO2007116909A1 (en) * | 2006-04-04 | 2009-08-20 | パナソニック株式会社 | Sample solution analysis panel |
US20080243309A2 (en) * | 2006-05-08 | 2008-10-02 | Auburn University | Systems for and methods of characterizing reactions |
US7384798B2 (en) * | 2006-10-31 | 2008-06-10 | Hewlett-Packard Development Company, L.P. | Method of detecting analytes in a microfluidic sample and a system for performing the same |
KR101228112B1 (en) * | 2006-12-06 | 2013-01-31 | 삼성전자주식회사 | Microfluidic device using centrifugal force and pump to control fluid movement and microfluidic system comprising the same |
ES2753136T3 (en) | 2006-12-22 | 2020-04-07 | Diasorin S P A | Thermal transfer methods for microfluidic systems |
KR20090105934A (en) * | 2006-12-22 | 2009-10-07 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | Enhanced sample processing devices, systems and methods |
KR101305976B1 (en) * | 2007-02-12 | 2013-09-12 | 삼성전자주식회사 | Centrifugal force based microfluidic device for serial dilution and microfluidic system comprising the same |
KR101278154B1 (en) * | 2007-04-16 | 2013-06-27 | 삼성전자주식회사 | Centrifugal force based microfluidic device, microfluidic system with the same, and method for determining a home position of the microfluidic device |
KR20080107212A (en) | 2007-06-05 | 2008-12-10 | 삼성전자주식회사 | Microfluidic apparatus with fluid container |
EP2017006A1 (en) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Microfluidic methods and systems for use in detecting analytes |
CN101918829A (en) * | 2007-11-20 | 2010-12-15 | 3M创新有限公司 | Pick-up unit and method |
US20090247902A1 (en) * | 2008-03-27 | 2009-10-01 | Reichert Julie A | Method and apparatus for transporting a patient sample between a sterile and non-sterile area |
KR20110020850A (en) * | 2008-05-23 | 2011-03-03 | 후지필름 가부시키가이샤 | Method and apparatus for substrate bonding |
FI120818B (en) * | 2008-05-28 | 2010-03-31 | Thermo Fisher Scientific Oy | Reaction vessel and method for treating it |
US8221299B2 (en) * | 2008-06-17 | 2012-07-17 | Bio-Rad Laboratories, Inc. | Centrifugal force-based system for detection/treatment of membrane-encased structures |
JP5238028B2 (en) * | 2008-07-22 | 2013-07-17 | アークレイ株式会社 | Microchip and analyzer |
KR101099495B1 (en) * | 2008-10-14 | 2011-12-28 | 삼성전자주식회사 | Centrifugal force-based microfluidic device, method of manufacturing the same and sample analysis method using the same |
USD638951S1 (en) | 2009-11-13 | 2011-05-31 | 3M Innovative Properties Company | Sample processing disk cover |
USD638550S1 (en) | 2009-11-13 | 2011-05-24 | 3M Innovative Properties Company | Sample processing disk cover |
USD667561S1 (en) | 2009-11-13 | 2012-09-18 | 3M Innovative Properties Company | Sample processing disk cover |
US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
WO2012158988A1 (en) | 2011-05-18 | 2012-11-22 | 3M Innovative Properties Company | Systems and methods for valving on a sample processing device |
ES2755078T3 (en) | 2011-05-18 | 2020-04-21 | Diasorin S P A | Systems and methods for volumetric measurement in a sample processing device |
USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
ES2870874T3 (en) | 2011-05-18 | 2021-10-27 | Diasorin S P A | Systems and methods for detecting the presence of a selected volume of material in a sample processing device |
KR101329649B1 (en) | 2011-10-26 | 2013-11-14 | 한국기초과학지원연구원 | Apparatus for high-throughput screening of protein crystalization using spiral microchannel and method using the same |
KR20130086743A (en) * | 2012-01-26 | 2013-08-05 | 삼성전자주식회사 | Microfluidic device and control method thereof |
JP6087272B2 (en) * | 2013-12-20 | 2017-03-01 | 信越ポリマー株式会社 | Analysis board |
US9757728B2 (en) * | 2016-01-26 | 2017-09-12 | Lidong Qin | Microfluidic aliquoting for single-cell isolation |
US11161107B2 (en) * | 2016-05-25 | 2021-11-02 | Integrated Micro-Chromatography Systems, Inc. | Dispersive pipette extraction system for purification of large biomolecules |
US11439970B2 (en) * | 2018-05-22 | 2022-09-13 | Microsoft Technology Licensing, Llc | DNA manufacturing, storage, and access system |
KR102401909B1 (en) * | 2018-08-30 | 2022-05-24 | 주식회사 엘지화학 | A high-speed screening analysis system for reaction optimization |
CN111778137B (en) * | 2020-06-29 | 2023-01-31 | 上海思路迪生物医学科技有限公司 | Three-degree-of-freedom library preparation card box and method |
US20220080416A1 (en) * | 2020-09-17 | 2022-03-17 | Citrogene Inc. | Microfluidic device and method for rapid high throughput identification of microorganisms |
CN113234571B (en) * | 2021-04-29 | 2023-08-25 | 杭州霆科生物科技有限公司 | High-flux enzyme screening chip |
WO2023059894A1 (en) * | 2021-10-08 | 2023-04-13 | Baebies, Inc. | Digital microfluidics multi-dynamic range parallel biochemical assays |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021090A1 (en) * | 1995-12-05 | 1997-06-12 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
WO1998053311A2 (en) * | 1997-05-23 | 1998-11-26 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3528449A (en) * | 1968-02-27 | 1970-09-15 | Trw Inc | Fluid flow control apparatus |
US3679367A (en) * | 1970-09-14 | 1972-07-25 | Technicon Instr | Apparatus for determining the pack volume of particulates in liquid mixtures |
US3713062A (en) * | 1970-12-29 | 1973-01-23 | Texas Instruments Inc | Snap disc thermal sequencer |
US3952116A (en) * | 1974-09-17 | 1976-04-20 | Texas Instruments Incorporated | Process for forming electrical resistance heaters |
US4030834A (en) * | 1976-04-08 | 1977-06-21 | The United States Of America As Represented By The United States Energy Research And Development Administration | Dynamic multistation photometer |
US4258740A (en) * | 1977-05-16 | 1981-03-31 | Packard Instrument Company, Inc. | Fluid flow control device |
FR2400700A1 (en) * | 1977-08-18 | 1979-03-16 | Guigan Jean | CONDITIONING DEVICE FOR A LIQUID SAMPLE FOR ANALYSIS |
FR2409514A1 (en) * | 1977-11-17 | 1979-06-15 | Bretaudiere Jean Pierre | DEVELOPMENT OF CENTRIFUGATION ANALYSIS EQUIPMENT |
US4381291A (en) * | 1979-02-23 | 1983-04-26 | Ab Fortia | Measurement of free ligands |
DE3044385A1 (en) * | 1980-11-25 | 1982-06-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR CARRYING OUT ANALYTICAL PROVISIONS AND ROTOR INSERT ELEMENT SUITABLE FOR THIS |
US4729862A (en) * | 1981-04-24 | 1988-03-08 | Allied-Signal Inc. | Nylon composition for use in rotational molding |
US5496520A (en) * | 1982-01-08 | 1996-03-05 | Kelton; Arden A. | Rotary fluid manipulator |
DE3314961A1 (en) * | 1983-04-25 | 1984-10-25 | Boehringer Mannheim Gmbh, 6800 Mannheim | ANALYZER FOR PHOTOMETRICALLY DETERMINING A PARAMETER OF A LIQUID |
GB8317124D0 (en) * | 1983-06-23 | 1983-07-27 | Ekins R P | Free ligand assay |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4612959A (en) * | 1985-05-07 | 1986-09-23 | Mobil Oil Corporation | Valveless shut-off and transfer device |
US4722853A (en) * | 1985-08-12 | 1988-02-02 | Raychem Corporation | Method of printing a polymer thick film ink |
US5171695A (en) * | 1986-08-06 | 1992-12-15 | Multilyte Limited | Determination of analyte concentration using two labelling markers |
US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US4872821A (en) * | 1987-03-23 | 1989-10-10 | Gold Medal Products Co. | Cotton candy machine |
US4940527A (en) * | 1987-06-01 | 1990-07-10 | Abbott Laboratories | Two-part test cartridge for centrifuge |
US5242803A (en) * | 1987-07-17 | 1993-09-07 | Martin Marietta Energy Systems, Inc. | Rotor assembly and assay method |
US5173262A (en) * | 1987-07-17 | 1992-12-22 | Martin Marietta Energy Systems, Inc. | Rotor assembly and method for automatically processing liquids |
US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
US5252294A (en) * | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
US5160702A (en) * | 1989-01-17 | 1992-11-03 | Molecular Devices Corporation | Analyzer with improved rotor structure |
US5171533A (en) * | 1989-07-31 | 1992-12-15 | Fine Richard A | Biological assay cassette and method for making same |
US5006749A (en) * | 1989-10-03 | 1991-04-09 | Regents Of The University Of California | Method and apparatus for using ultrasonic energy for moving microminiature elements |
US5173193A (en) * | 1991-04-01 | 1992-12-22 | Schembri Carol T | Centrifugal rotor having flow partition |
US5122284A (en) * | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
US5242606A (en) * | 1990-06-04 | 1993-09-07 | Abaxis, Incorporated | Sample metering port for analytical rotor having overflow chamber |
US5186844A (en) * | 1991-04-01 | 1993-02-16 | Abaxis, Inc. | Apparatus and method for continuous centrifugal blood cell separation |
US5061381A (en) * | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
US5210664A (en) | 1991-05-28 | 1993-05-11 | Iomega Corporation | Low profile tape drive for driving a mini-data cartridge |
US5413732A (en) * | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
DE4140554A1 (en) * | 1991-12-09 | 1993-06-17 | Biedermann Motech Gmbh | KNEE ORTHESIS |
US5304348A (en) * | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
WO1993019827A1 (en) * | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
US5275016A (en) * | 1992-04-24 | 1994-01-04 | Abaxis, Inc. | Cryogenic apparatus |
EP0637996B1 (en) | 1992-05-01 | 1997-07-23 | The Trustees Of The University Of Pennsylvania | Microfabricated detection structures |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
GB2280448B (en) * | 1993-01-29 | 1996-05-22 | Pentel Kk | Aqueous metallic ink for ball-point pen |
US5478750A (en) * | 1993-03-31 | 1995-12-26 | Abaxis, Inc. | Methods for photometric analysis |
KR960703174A (en) | 1993-06-09 | 1996-06-19 | 미안 알렉 | MAGNETIC CYCLE REACTION |
US5432009A (en) * | 1993-06-17 | 1995-07-11 | Sekisui Kagaku Kogyo Kabushiki Kaisha | Film for first-aid sticking plaster |
US5368704A (en) * | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
US5409665A (en) * | 1993-09-01 | 1995-04-25 | Abaxis, Inc. | Simultaneous cuvette filling with means to isolate cuvettes |
US5591643A (en) * | 1993-09-01 | 1997-01-07 | Abaxis, Inc. | Simplified inlet channels |
US5431303A (en) * | 1993-09-30 | 1995-07-11 | Miskell; David L. | Two-part aerosol dispenser employing fusible plug |
US5403415A (en) * | 1993-11-17 | 1995-04-04 | Abaxis, Inc. | Method and device for ultrasonic welding |
US5413009A (en) * | 1994-03-16 | 1995-05-09 | Fragnito; Frank | Variable speed transmission assembly |
US5590052A (en) * | 1994-04-14 | 1996-12-31 | Abaxis, Inc. | Error checking in blood analyzer |
US5639428A (en) * | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
US5876187A (en) * | 1995-03-09 | 1999-03-02 | University Of Washington | Micropumps with fixed valves |
US5622819A (en) * | 1995-03-28 | 1997-04-22 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
US20010055812A1 (en) | 1995-12-05 | 2001-12-27 | Alec Mian | Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
AU5895898A (en) * | 1996-12-20 | 1998-07-17 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
US6632399B1 (en) * | 1998-05-22 | 2003-10-14 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays |
EP1004015B1 (en) * | 1997-08-15 | 2004-01-02 | Alexion Pharmaceuticals, Inc. | Apparatus for performing assays at reaction sites |
US5842787A (en) * | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
US6459080B1 (en) * | 1998-06-12 | 2002-10-01 | Agilent Technologies, Inc. | Miniaturized device for separating the constituents of a sample and delivering the constituents of the separated sample to a mass spectrometer |
EP1230544B1 (en) * | 1999-06-18 | 2004-07-28 | Gamera Bioscience Corporation | Devices and methods for the performance of miniaturized homogeneous assays |
US6258263B1 (en) * | 1999-09-17 | 2001-07-10 | The University Of Cincinnati | Liquid chromatograph on a chip |
WO2002037096A1 (en) * | 1999-10-01 | 2002-05-10 | University Of California | Microfabricated liquid sample loading system |
US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
EP1284818B1 (en) * | 2000-05-15 | 2006-11-22 | Tecan Trading AG | Bidirectional flow centrifugal microfluidic devices |
US6653122B2 (en) * | 2001-04-24 | 2003-11-25 | Dade Microscan Inc. | Indentification test device in a random access microbiological analyzer |
US6627076B2 (en) * | 2001-10-19 | 2003-09-30 | Sandia National Laboratories | Compact microchannel system |
-
2000
- 2000-06-16 EP EP00939944A patent/EP1230544B1/en not_active Expired - Lifetime
- 2000-06-16 AU AU54949/00A patent/AU5494900A/en not_active Abandoned
- 2000-06-16 JP JP2001505200A patent/JP2004529312A/en active Pending
- 2000-06-16 WO PCT/US2000/016653 patent/WO2000079285A2/en active IP Right Grant
- 2000-06-16 US US09/595,239 patent/US6582662B1/en not_active Expired - Fee Related
- 2000-06-16 AT AT00939944T patent/ATE272213T1/en not_active IP Right Cessation
- 2000-06-16 DE DE60012562T patent/DE60012562D1/en not_active Expired - Lifetime
-
2003
- 2003-06-24 US US10/602,564 patent/US20030232403A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021090A1 (en) * | 1995-12-05 | 1997-06-12 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
WO1998053311A2 (en) * | 1997-05-23 | 1998-11-26 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7939018B2 (en) | 2000-06-28 | 2011-05-10 | 3M Innovative Properties Company | Multi-format sample processing devices and systems |
US8003051B2 (en) | 2001-12-28 | 2011-08-23 | 3M Innovative Properties Company | Thermal structure for sample processing systems |
Also Published As
Publication number | Publication date |
---|---|
EP1230544A2 (en) | 2002-08-14 |
US6582662B1 (en) | 2003-06-24 |
WO2000079285A9 (en) | 2002-10-03 |
AU5494900A (en) | 2001-01-09 |
JP2004529312A (en) | 2004-09-24 |
WO2000079285A2 (en) | 2000-12-28 |
US20030232403A1 (en) | 2003-12-18 |
DE60012562D1 (en) | 2004-09-02 |
ATE272213T1 (en) | 2004-08-15 |
EP1230544B1 (en) | 2004-07-28 |
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