WO2000049951A1 - An adapter for vascular anastomoses - Google Patents

An adapter for vascular anastomoses Download PDF

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Publication number
WO2000049951A1
WO2000049951A1 PCT/IT2000/000058 IT0000058W WO0049951A1 WO 2000049951 A1 WO2000049951 A1 WO 2000049951A1 IT 0000058 W IT0000058 W IT 0000058W WO 0049951 A1 WO0049951 A1 WO 0049951A1
Authority
WO
WIPO (PCT)
Prior art keywords
adapter
branch conduit
adapter according
conduit
conduits
Prior art date
Application number
PCT/IT2000/000058
Other languages
French (fr)
Inventor
Mariano Gargiulo
Gennaro Quarto
Original Assignee
Mariano Gargiulo
Gennaro Quarto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mariano Gargiulo, Gennaro Quarto filed Critical Mariano Gargiulo
Priority to AU31906/00A priority Critical patent/AU3190600A/en
Publication of WO2000049951A1 publication Critical patent/WO2000049951A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/064Blood vessels with special features to facilitate anastomotic coupling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B2017/1135End-to-side connections, e.g. T- or Y-connections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B2017/1139Side-to-side connections, e.g. shunt or X-connections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/065Y-shaped blood vessels

Definitions

  • This invention relates to an adapter for vascular anastomoses. More particularly, this invention relates to an adapter of the above mentioned kind that enables in reliable and economically feasible way to simplify and speed-up the installation of vascular anastomoses in order to improve the results that can be obtained.
  • vascular by-pass represents the surgical treatment of occlusive diseases of arterial, venous or lymphatic vessels as well as in aneurysms.
  • a vascular by-pass in which an artifact conjunction between interested hollow structures is realized by means of a prosthetic structure, becomes necessary in all those subjects in which particular disease conditions or traumatic events resulted into stenosis, occlusion or dilatation of the vessels.
  • a vascular by-pass provides for installation of a connection bridge made of bio-compatible or biologic (autologous, homologous or eterologous) synthetic material designed to span the deteriorated segment, in order to restore the normal arterial, venous or lymphatic circulation.
  • the vessels interested in this intervent can be two or more than two.
  • the intervent includes the insertion of the vascular prosthesis, suitably dimensioned by the surgeon during the inten/ent itself, upon suitably shaping its ends according to the needs (for instance with a so-called clarinet beak cut), onto the one or more interested vessels upstream and downstream the deteriorated segment.
  • the recently performed by-pass intervents in the frame of video-aided surgery contemplate the realization of the anastomoses as the moment of maximum technical difficulty.
  • an adapter for vascular anastomoses having perimetral edges, characterized in that it comprises at least one main conduit and at least one branch conduit, the prosthesis being realized in bio-compatible material, preferably Dacron® and/or GoreTex® and/or PTFE and/or polyurethane and/or Nitinol® and/or ePTFE.
  • the adapter can comprise a single main conduit and the axes of the main conduit and of said at least one branch conduit can include an acute angle in the range of 15° to 75°, preferably in the range of 25° to 45°. Still according to this invention, the adapter can comprise two main conduits and a single branch conduit.
  • At least one branch conduit can comprise a second order branch conduit, the axes of said at least one branch conduit and of said at least one second order branch conduit including an acute angle in the range of 15° to 75°, preferably in the range of 25° to 45°.
  • At least one of the conduits of the adapter is of cylindrical or frusto-conical shape and/or it has a circular cross-section.
  • at least one of the conduits of the adapter can have one or more apertures in its external wall.
  • at least one of the conduits of the adapter can be provided with suitably shaped weakness lines in its external wall adapted to be cut so as to remove at least a portion of said external wall.
  • said perimetral edges are tapered and/or realized with partially bio-degradable and/or shape recovering materials.
  • At least one of the conduits of the adapter can be provided with an internal metal bio-compatible core, preferably of steel and/or titanium and/or a shape recovering material.
  • Figure 1 is a perspective view of a first embodiment of the adapter for vascular anastomoses according to this invention
  • Figure 2 is a perspective view of a second embodiment of the adapter for vascular anastomoses according to this invention
  • Figure 3 is a perspective view of a third embodiment of the adapter for vascular anastomoses according to this invention.
  • Figure 4 is a perspective view of a fourth embodiment of the adapter for vascular anastomoses according to this invention.
  • the adapter for vascular anastomoses comprises a main conduit 1 communicating with a branch conduit 2.
  • Said main conduit 1 and said branch conduit 2 have a cylindrical or frusto-conical shape, with circular cross-section.
  • the axes of said main conduit 1 and said branch conduit 2 include an acute angle ⁇ in the range of 15° to 75°, preferably in the range of 25° to 45°.
  • the adapter according to this invention is realized with bio- compatible materials, such as, for instance, Dacron®, Gore-Tex®, PTFE, polyurethane, Nitinol®, ePTFE.
  • bio- compatible materials such as, for instance, Dacron®, Gore-Tex®, PTFE, polyurethane, Nitinol®, ePTFE.
  • the main conduit 1 communicates with a single branch conduit 2 and the length of said main conduit 1 is greater than the length of said branch conduit 2. It should be understood, however, that those skilled in the art will be certainly able to modify the adapter according to this invention by providing more than one branch conduit 2 communicating with the main conduit 1 and/or said main conduit 1 can also be no longer than said branch conduit 2, without so departing from the scope of this invention.
  • the free ends of said main conduit 1 can be tapered and/or realized with special partially bio- degradable and/or foamable materials of shape recovering type, that is to say such materials that at temperatures lower than the physiologic temperatures can be stored in slightly deformed condition and at physiologic temperatures they recover their original shape.
  • the free ends of said main conduit 1 could also be maintained in a compressed diameter configuration and, as soon as they are warmed-up by contact with the blood or lymph stream, they dilatate so as to adhere to the internal wall of the vessel into which the adapter is inserted.
  • the installation of a vascular anastomosis is noticeably simplified, which results into dramatically decreasing the necessary times for execution of the related operations as well as into significantly improving the outcome that can be achieved, which, in turn, is substantially independent of the operator's skillness.
  • a second embodiment of the adapter according to this invention further comprises a second order branch conduit 3 departing from said branch conduit 2.
  • Said second order branch conduit 3 also has a cylindrical or frusto-conical shape with a circular cross-section.
  • the axes of said branch conduit 2 and of said second order branch conduit 3 include an acute angle ⁇ in the range of 15° to 75°, preferably in the range of 25° to 45°.
  • the embodiment shown in Figure 2 enables to utilize the adapter according to this invention in realizing a vascular anastomosis in which it is necessary to realize multiple connections corresponding to a particular vessel. For instance, this is the case in which a prosthetic sequential aortal-femoral and femoral-distal bridge is to be realized such that an adapter according to Figure 2 can be inserted in corresponding position to the junction of the femoral vessel.
  • a third embodiment of the adapter according to this invention comprises two main conduits 1 and 1' both communicating with a branch conduit 2.
  • FIG. 3 enables to utilize the adapter in performing arterial-venous vents, for instance in the case of dialyzed patients. It is well known to those skilled in the art that a natural branching can be present in corresponding position to the connection of a vascular prosthesis. In such cases, the adapters illustrated in Figures 1, 2 and 3 could occlude the related connection mouth.
  • a fourth embodiment of the adapter according to this invention as shown in Figure 4, provides for the main conduit 1 to have apertures 4 in its external wall adapted to prevent any connection mouths to further blood vessels from being occluded.
  • the perimetral edges of said apertures 4 can be tapered and /or realized with special partially bio-degradable and/or foamable shape recovering materials so as to minimize the step effect that can be generated in the lumen of the vessel.
  • the adapter of Figure 4 is related to the one of Figure 1; it should be understood that similar embodiments of the adapter could also be realized in respect of the embodiments of Figures 2 and 3, without so departing from the scope of this invention.
  • an adapter having three apertures 4 in its lateral wall is shown in Figure 4. It should be understood, however, that the number of said apertures 4 in the lateral wall can also be different from three, without so departing from the scope of this invention.
  • the external wall of the main conduit (not shown in the Figures) provides for the external wall of the main conduit to have suitably shaped weakness lines that can be cut open by the surgeon during the inte ⁇ ent in order to remove some portions of the external wall, so as to connect the adapter to junction areas where natural branchings are present.
  • a metal core such as a wire network
  • such core is realized with inert bio-compatible materials, such as, for instance, steel and titanium and/or foamable shape recovering materials.

Abstract

An adapter for vascular anastomoses having perimetral edges, characterized in that it comprises at least one main conduit (1, 1') and at least one branch conduit (2), the prosthesis being realized with bio-compatible material.

Description

AN ADAPTER FORVASCULARANASTOMOSES
This invention relates to an adapter for vascular anastomoses. More particularly, this invention relates to an adapter of the above mentioned kind that enables in reliable and economically feasible way to simplify and speed-up the installation of vascular anastomoses in order to improve the results that can be obtained.
It is known that one of the most frequent surgical intervents is the installation off a vascular by-pass, which represents the surgical treatment of occlusive diseases of arterial, venous or lymphatic vessels as well as in aneurysms. In particular, a vascular by-pass in which an artifact conjunction between interested hollow structures is realized by means of a prosthetic structure, becomes necessary in all those subjects in which particular disease conditions or traumatic events resulted into stenosis, occlusion or dilatation of the vessels.
The installation of a vascular by-pass provides for installation of a connection bridge made of bio-compatible or biologic (autologous, homologous or eterologous) synthetic material designed to span the deteriorated segment, in order to restore the normal arterial, venous or lymphatic circulation. When extended vascular pathologies are involved, the vessels interested in this intervent can be two or more than two. The intervent includes the insertion of the vascular prosthesis, suitably dimensioned by the surgeon during the inten/ent itself, upon suitably shaping its ends according to the needs (for instance with a so-called clarinet beak cut), onto the one or more interested vessels upstream and downstream the deteriorated segment.
The difficulties connected with installing a vascular anastomosis (namely the suturation between interested hollow structures) are quite apparent to those skilled in the art. The problems arising in suitably shaping the connection orifices as well as in inserting the vascular prosthesis into the usually weakened walls of the interested vessels can be mentioned by way of exemplification.
This entails intervents of extremely long durations, variable as a function of the difficulties to be solved, that can make it necessary to realize a number of anastomoses during the same intervent. In this respect, it has been shown that, for instance, a prolonged duration of an intervent amounts to a significant infection risk for the vascular prosthesis, as well as to an increased surgical risk in general terms. Furthermore, the outcome of the intervents depends in noticeable amount on the specific skillness of the surgeon, with the risk of technical inaccuracies that can make a reintervention necessary.
Again, the difficulties in vascular anostomoses make the installation of a by-pass on vessels of small diameter very hard.
Additionally, the recently performed by-pass intervents in the frame of video-aided surgery contemplate the realization of the anastomoses as the moment of maximum technical difficulty.
In this contest, it is the object of this invention, therefore, to provide in reliable and economically feasible manner ail suitable means to solve all above mentioned problems and to enable to simplify and to speed-up the realization of vascular anastomoses, thereby improving and making the results of such operations as much as possible independent of the skillness of the surgeon. It is specific subject matter of this invention an adapter for vascular anastomoses, having perimetral edges, characterized in that it comprises at least one main conduit and at least one branch conduit, the prosthesis being realized in bio-compatible material, preferably Dacron® and/or GoreTex® and/or PTFE and/or polyurethane and/or Nitinol® and/or ePTFE.
According to this invention, the adapter can comprise a single main conduit and the axes of the main conduit and of said at least one branch conduit can include an acute angle in the range of 15° to 75°, preferably in the range of 25° to 45°. Still according to this invention, the adapter can comprise two main conduits and a single branch conduit.
Further according to this invention, at least one branch conduit can comprise a second order branch conduit, the axes of said at least one branch conduit and of said at least one second order branch conduit including an acute angle in the range of 15° to 75°, preferably in the range of 25° to 45°.
Preferably according to this invention, at least one of the conduits of the adapter is of cylindrical or frusto-conical shape and/or it has a circular cross-section. Again according to this invention, at least one of the conduits of the adapter can have one or more apertures in its external wall. Again according to this invention, at least one of the conduits of the adapter can be provided with suitably shaped weakness lines in its external wall adapted to be cut so as to remove at least a portion of said external wall. Preferably according to this invention, said perimetral edges are tapered and/or realized with partially bio-degradable and/or shape recovering materials.
Further according to this invention, at least one of the conduits of the adapter can be provided with an internal metal bio-compatible core, preferably of steel and/or titanium and/or a shape recovering material.
This invention will be hereinafter described, by way of illustration, not by way of limitation, according to its preferred embodiments, by particularly referring to the Figures of the enclosed drawings, in which: Figure 1 is a perspective view of a first embodiment of the adapter for vascular anastomoses according to this invention,
Figure 2 is a perspective view of a second embodiment of the adapter for vascular anastomoses according to this invention,
Figure 3 is a perspective view of a third embodiment of the adapter for vascular anastomoses according to this invention,
Figure 4 is a perspective view of a fourth embodiment of the adapter for vascular anastomoses according to this invention.
Similar reference numerals will be utilized in the following description to designate similar items in the Figures. By referring now to Figure 1, it can be observed that the adapter for vascular anastomoses according to this invention comprises a main conduit 1 communicating with a branch conduit 2. Said main conduit 1 and said branch conduit 2 have a cylindrical or frusto-conical shape, with circular cross-section. The axes of said main conduit 1 and said branch conduit 2 include an acute angle α in the range of 15° to 75°, preferably in the range of 25° to 45°.
The adapter according to this invention is realized with bio- compatible materials, such as, for instance, Dacron®, Gore-Tex®, PTFE, polyurethane, Nitinol®, ePTFE. As it appears in Figure 1, the main conduit 1 communicates with a single branch conduit 2 and the length of said main conduit 1 is greater than the length of said branch conduit 2. It should be understood, however, that those skilled in the art will be certainly able to modify the adapter according to this invention by providing more than one branch conduit 2 communicating with the main conduit 1 and/or said main conduit 1 can also be no longer than said branch conduit 2, without so departing from the scope of this invention.
Aiming at better illustrating this invention, the employment modes of the preferred embodiment of the adapter for vascular anastomoses will be hereinbelow described, in the assumption that similar modes also apply for the remaining embodiments. During the realization of a vascular anastomosis, for performing the connection between the vascular prosthesis and the interested vessel, it sufficient to cut open the wall of the interested vessel, to insert the main conduit 1 of the adapter thereinto and to fix it in place. The vascular prosthesis is subsequently externally fixed to the free end of the branch conduit 2 of the adapter.
Aiming at minimizing the step effect that is generated in the lumen of the vessel as well as at enabling an optimum match to be realized between prosthesis and vessel, the free ends of said main conduit 1 can be tapered and/or realized with special partially bio- degradable and/or foamable materials of shape recovering type, that is to say such materials that at temperatures lower than the physiologic temperatures can be stored in slightly deformed condition and at physiologic temperatures they recover their original shape. As far as the adapter according to this invention in concerned, the free ends of said main conduit 1 , realized with the above mentioned shape recovering materials, could also be maintained in a compressed diameter configuration and, as soon as they are warmed-up by contact with the blood or lymph stream, they dilatate so as to adhere to the internal wall of the vessel into which the adapter is inserted. It will be apparent to those skilled in the art that, by utilizing the adapter according to this invention, the installation of a vascular anastomosis is noticeably simplified, which results into dramatically decreasing the necessary times for execution of the related operations as well as into significantly improving the outcome that can be achieved, which, in turn, is substantially independent of the operator's skillness.
By referring to figure 2, it can be observed that a second embodiment of the adapter according to this invention further comprises a second order branch conduit 3 departing from said branch conduit 2. Said second order branch conduit 3 also has a cylindrical or frusto-conical shape with a circular cross-section. The axes of said branch conduit 2 and of said second order branch conduit 3 include an acute angle β in the range of 15° to 75°, preferably in the range of 25° to 45°.
In Figure 2, the axes of the main conduit 1, of the branch conduit 2 and of the second order branch conduit 3 are co-planar. It should be understood, however, that those skilled in the art can easily modify the adapter according to this invention by realizing said three conduits 1 , 2 and 3 with non co-planar axes, without so departing from the scope of this invention.
The embodiment shown in Figure 2 enables to utilize the adapter according to this invention in realizing a vascular anastomosis in which it is necessary to realize multiple connections corresponding to a particular vessel. For instance, this is the case in which a prosthetic sequential aortal-femoral and femoral-distal bridge is to be realized such that an adapter according to Figure 2 can be inserted in corresponding position to the junction of the femoral vessel.
By referring to Figure 3, it can be observed that a third embodiment of the adapter according to this invention comprises two main conduits 1 and 1' both communicating with a branch conduit 2.
The embodiment of Figure 3 enables to utilize the adapter in performing arterial-venous vents, for instance in the case of dialyzed patients. It is well known to those skilled in the art that a natural branching can be present in corresponding position to the connection of a vascular prosthesis. In such cases, the adapters illustrated in Figures 1, 2 and 3 could occlude the related connection mouth. To overcome such a drawback, a fourth embodiment of the adapter according to this invention, as shown in Figure 4, provides for the main conduit 1 to have apertures 4 in its external wall adapted to prevent any connection mouths to further blood vessels from being occluded. Also in this case, the perimetral edges of said apertures 4 can be tapered and /or realized with special partially bio-degradable and/or foamable shape recovering materials so as to minimize the step effect that can be generated in the lumen of the vessel. The adapter of Figure 4 is related to the one of Figure 1; it should be understood that similar embodiments of the adapter could also be realized in respect of the embodiments of Figures 2 and 3, without so departing from the scope of this invention.
Furthermore, an adapter having three apertures 4 in its lateral wall is shown in Figure 4. It should be understood, however, that the number of said apertures 4 in the lateral wall can also be different from three, without so departing from the scope of this invention.
A fifth embodiment of the adapter according to this invention
(not shown in the Figures) provides for the external wall of the main conduit to have suitably shaped weakness lines that can be cut open by the surgeon during the inteπ ent in order to remove some portions of the external wall, so as to connect the adapter to junction areas where natural branchings are present.
Further embodiments of the adapter according to this invention can also be provided with a metal core, such as a wire network, internally incorporated with the material of the adapter itself. In particular, such core is realized with inert bio-compatible materials, such as, for instance, steel and titanium and/or foamable shape recovering materials.
The utilization of the adapter for vascular anastomoses according to this invention makes the application of by-passes to vessels of small diameter possible.
Furthermore, the simplification realized in installing a vascular anastomosis by utilizing the adapter according to this invention makes it easier to apply methods of video-assisted surgery, that are less invasive than the presently utilized conventional surgery techniques. This invention has been hereinbefore explained by way of illustration, but not by way of limitation, according to its preferred embodiment, but it should be understood that those skilled in the art can made variations and/or changes therein without departing from the scope of this invention, as defined in the attached claims.

Claims

1.- An adapter for vascular anastomoses having perimetral edges, characterized in that it comprises at least one main conduit (1, 1') and at least one branch conduit (2), the prosthesis being realized with bio- compatible material.
2.- An adapter according to claim 1 , characterized in that it comprises a single main conduit (1) and in that the axes of the main conduit (1) and of said at least one branch conduit (2) can include an acute angle (α) in the range of 15° to 75°.
3.- An adapter according to claim 2, characterized in that the axes of the main conduit (1 ) and of said at least one branch conduit (2) include an acute angle (α) in the range of 25° to 45°.
4.- An adapter according to claim 1 , characterized in that it comprises two main conduits (1 , 1') and a single branch conduit (2).
5.- An adapter according to any one of the preceding claims, characterized in that at least one branch conduit (2) comprises a second order branch conduit (3), the axes of said at least one branch conduit (2) and of said at least one second order branch conduit (3) including an acute angle (β) in the range of 15° to 75°.
6.- An adapter according to claim 5, characterized in that the axes of said at least one branch conduit (2) and of said at least one second order branch conduit (3) include an acute angle (β) in the range of 25° to 45°.
7.- An adapter according to any one of the preceding claims, characterized in that at least one of the conduits (1 , 1', 2, 3) of the adapter has cylindrical or frusto-conical shape.
8.- An adapter according to any one of the preceding claims, characterized in that at least one of the conduits (1 , 1', 2, 3) of the adapter has a circular cross-section.
9.- An adapter according to any one of the preceding claims, characterized in that at least one of the conduits (1 , 1', 2, 3) of the adapter has one or more apertures (4) in its external wall.
10.- An adapter according to any one of the preceding claims, characterized in that at least one of the conduits (1 , 1', 2, 3) of the adapter is provided with suitably shaped weakness lines in its external wall adapted to be cut so as to remove at least a portion of said external wall.
11.- An adapter according to any one of the preceding claims, characterized in that said bio-compatible material is Dacron® and/or GoreTex® and/or PTFE and/or polyurethane and/or Nitinol® and/or ePTFE.
12.- An adapter according to any one of the preceding claims, characterized in that said perimetral edges are tapered and/or realized with partially bio-degradable and/or shape recovering materials.
13.- An adapter according to any one of the preceding claims, characterized in that at least one of the conduits (1 , 1', 2, 3) of the adapter is provided with an internal bio-compatible metal core.
14.- An adapter according to claim 13, characterized in that said internal metal bio-compatible core consists of steel and/or titanium and/or a shape recovering material.
15.- An adapter for vascular anastomosis according to any one of the preceding claims, substantially as illustrated and described.
PCT/IT2000/000058 1999-02-24 2000-02-23 An adapter for vascular anastomoses WO2000049951A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU31906/00A AU3190600A (en) 1999-02-24 2000-02-23 An adapter for vascular anastomoses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM990127 IT1305301B1 (en) 1999-02-24 1999-02-24 FITTING FOR VASCULAR ANASTOMOSIS.
ITRM99A000127 1999-02-24

Publications (1)

Publication Number Publication Date
WO2000049951A1 true WO2000049951A1 (en) 2000-08-31

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AU (1) AU3190600A (en)
IT (1) IT1305301B1 (en)
WO (1) WO2000049951A1 (en)

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FR2869527A1 (en) * 2004-04-28 2005-11-04 Raouf Ayman Abdul A vascular prosthesis for arterial anastomoses comprising two end portions each including an inflatable support (stent) connected to a bypass as a unitary ensemble
WO2011090640A1 (en) * 2010-01-22 2011-07-28 Valentin Kramer Composite arterial-venous shunt system
WO2012037558A1 (en) * 2010-09-17 2012-03-22 Bioconnect Systems Implantable graft connector
EP2477558A1 (en) * 2009-09-14 2012-07-25 CircuLite, Inc. Endovascular anastomotic connector device, delivery system, and methods of delivery and use
US8690816B2 (en) 2007-08-02 2014-04-08 Bioconnect Systems, Inc. Implantable flow connector
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US9094504B2 (en) 2000-09-11 2015-07-28 Transnexus, Inc. Clearinghouse server for internet telephony and multimedia communications
US9282967B2 (en) 2007-08-02 2016-03-15 Bioconnect Systems, Inc. Implantable flow connector
US9427340B2 (en) 2004-12-14 2016-08-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US9492297B2 (en) 2006-09-12 2016-11-15 Boston Scientific Scimed, Inc. Multilayer balloon for bifurcated stent delivery and methods of making and using the same
US10434293B2 (en) 2012-04-15 2019-10-08 Tva Medical, Inc. Implantable flow connector
US10632293B2 (en) 2012-04-15 2020-04-28 Tva Medical, Inc. Delivery system for implantable flow connector
EP3705088A1 (en) * 2019-03-06 2020-09-09 JOTEC GmbH Bifurcated stent graft and method of production thereof

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