WO2000019883A3 - Compositions and methods of disease diagnosis and therapy - Google Patents
Compositions and methods of disease diagnosis and therapy Download PDFInfo
- Publication number
- WO2000019883A3 WO2000019883A3 PCT/US1999/023418 US9923418W WO0019883A3 WO 2000019883 A3 WO2000019883 A3 WO 2000019883A3 US 9923418 W US9923418 W US 9923418W WO 0019883 A3 WO0019883 A3 WO 0019883A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- mutation
- gene
- detecting
- blood
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99954782A EP1129217A4 (en) | 1998-10-07 | 1999-10-07 | Compositions and methods of disease diagnosis and therapy |
AU11047/00A AU776917B2 (en) | 1998-10-07 | 1999-10-07 | Compositions and methods of disease diagnosis and therapy |
JP2000573246A JP2003529315A (en) | 1998-10-07 | 1999-10-07 | Components and methods for disease diagnosis and treatment |
CA002346765A CA2346765A1 (en) | 1998-10-07 | 1999-10-07 | Compositions and methods of disease diagnosis and therapy |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16775098A | 1998-10-07 | 1998-10-07 | |
US22122298A | 1998-12-28 | 1998-12-28 | |
US09/270,542 | 1999-03-17 | ||
US09/167,750 | 1999-03-17 | ||
US09/221,222 | 1999-03-17 | ||
US09/270,542 US6322976B1 (en) | 1998-05-28 | 1999-03-17 | Compositions and methods of disease diagnosis and therapy |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000019883A2 WO2000019883A2 (en) | 2000-04-13 |
WO2000019883A3 true WO2000019883A3 (en) | 2000-09-08 |
WO2000019883A9 WO2000019883A9 (en) | 2000-10-19 |
Family
ID=27389441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/023418 WO2000019883A2 (en) | 1998-10-07 | 1999-10-07 | Compositions and methods of disease diagnosis and therapy |
Country Status (6)
Country | Link |
---|---|
US (1) | US6322976B1 (en) |
EP (1) | EP1129217A4 (en) |
JP (1) | JP2003529315A (en) |
AU (1) | AU776917B2 (en) |
CA (1) | CA2346765A1 (en) |
WO (1) | WO2000019883A2 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6486299B1 (en) * | 1998-09-28 | 2002-11-26 | Curagen Corporation | Genes and proteins predictive and therapeutic for stroke, hypertension, diabetes and obesity |
GB9927502D0 (en) * | 1999-11-19 | 2000-01-19 | Isis Innovation | CD36 Polymorphisms |
EP1162458A1 (en) * | 2000-06-05 | 2001-12-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods and compositions for modulating oxidized LDL transport |
WO2002016947A2 (en) * | 2000-08-21 | 2002-02-28 | Queen's University At Kingston | Methods and kits for separation and detection of proteins in biological samples |
WO2002090979A1 (en) * | 2001-05-08 | 2002-11-14 | Histatek, Inc. | Biochips and method of screening using drug induced gene and protein expression profiling |
US20080200453A1 (en) | 2002-07-29 | 2008-08-21 | Cincotta Anthony H | Methods of treating metabolic syndrome using dopamine receptor agonists |
US9655865B2 (en) | 2002-07-29 | 2017-05-23 | Veroscience, Llc | Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes |
US20040220190A1 (en) * | 2002-07-29 | 2004-11-04 | Cincotta Anthony H. | Methods of treating metabolic syndrome using dopamine receptor agonists |
US20040081678A1 (en) * | 2002-08-09 | 2004-04-29 | Anthony Cincotta | Therapeutic process for the treatment of obesity and associated metabolic disorders |
US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
US20040077567A1 (en) * | 2002-10-16 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of CD36 expression |
US20040076621A1 (en) * | 2002-10-16 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of CD36 expression |
CN1833034B (en) * | 2003-06-20 | 2014-04-16 | 埃克斯魁恩公司 | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
US8137993B2 (en) * | 2004-03-25 | 2012-03-20 | Veroscience Llc | Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof |
US20050215558A1 (en) * | 2004-03-25 | 2005-09-29 | Cincotta Anthony H | Methods of identifying responders to dopamine agonist therapy |
US8137994B2 (en) * | 2004-03-25 | 2012-03-20 | Veroscience Llc | Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof |
US8080374B2 (en) * | 2004-05-11 | 2011-12-20 | Joslin Diabetes Center, Inc. | Methods of diagnosing cardiovascular disease |
ES2571929T3 (en) * | 2004-05-26 | 2016-05-27 | Region Nordjylland | Procedure to determine the amount of circulating CD36 |
EP1754058B1 (en) * | 2004-05-26 | 2016-04-13 | Region Nordjylland | Method for determining the amount of circulating CD36 |
US20070020657A1 (en) * | 2005-05-20 | 2007-01-25 | Grebe Stefan K | Methods for detecting circulating tumor cells |
JP5175501B2 (en) * | 2006-11-15 | 2013-04-03 | ニプロ株式会社 | Test strip for detecting drug sensitivity in Mycobacterium tuberculosis |
WO2009128734A1 (en) * | 2008-04-18 | 2009-10-22 | Vialactia Biosciences (Nz) Limited | Marker assisted identification of mammals for desired phenotypic trait |
US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
CN103037901B (en) * | 2010-06-01 | 2018-04-27 | 康奈尔大学 | Suppress CD36 with obesity controlling and insulin sensitivity |
WO2012149465A2 (en) * | 2011-04-27 | 2012-11-01 | Isis Pharmaceuticals, Inc. | Modulation of cd36 expression |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993006849A1 (en) * | 1991-10-03 | 1993-04-15 | The Center For Blood Research | Binding of plasmodium falciparum-infected erythrocytes to cd36 |
US5338839A (en) * | 1988-04-12 | 1994-08-16 | Massachusetts Institute Of Technology | DNA encoding nestin protein |
US5506126A (en) * | 1988-02-25 | 1996-04-09 | The General Hospital Corporation | Rapid immunoselection cloning method |
US5629158A (en) * | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
US5871931A (en) * | 1995-06-30 | 1999-02-16 | Millennium Pharmaceuticals, Inc. | Methods for detecting mammalian tub protein and RNA |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2422956A1 (en) | 1978-04-13 | 1979-11-09 | Pasteur Institut | METHOD OF DETECTION AND CHARACTERIZATION OF A NUCLEIC ACID OR OF A SEQUENCE OF THE SAME, AND ENZYMATIC REAGENT FOR THE IMPLEMENTATION OF THIS PROCESS |
NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
NO169351C (en) | 1987-10-02 | 1992-06-10 | Boerresen Anne Lise | MASS TEST METHOD FOR THE DETECTION OF SINGLE BASE MUTIONS IN MULTIPLE LOCI IN GENOMIC DNA BY USING DENATURING GRADIENT GELELECTROPHORESIS EFFECTIVE OF EFFECTIVE TRANSFER AND HYBRIDIZATION FOR HYBRIDIZATION |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
CA2093427C (en) * | 1990-10-17 | 2008-01-15 | Marvin S. Reitz, Jr. | Molecular clones of hiv-1 and uses thereof |
US5976789A (en) * | 1991-07-17 | 1999-11-02 | Bio Merieux | System of probes enabling HLA-DR typing to be performed, and typing method using said probes |
US5837832A (en) * | 1993-06-25 | 1998-11-17 | Affymetrix, Inc. | Arrays of nucleic acid probes on biological chips |
US5834183A (en) * | 1993-06-29 | 1998-11-10 | Regents Of The University Of Minnesota | Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis |
AU8126694A (en) * | 1993-10-26 | 1995-05-22 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
US5550020A (en) * | 1994-07-08 | 1996-08-27 | Visible Genetics Inc. | Method, reagents and kit for diagnosis and targeted screening for retinoblastoma |
US5992926A (en) * | 1997-07-30 | 1999-11-30 | Dana Corporation | Vehicular skid plate and cross member assembly |
-
1999
- 1999-03-17 US US09/270,542 patent/US6322976B1/en not_active Expired - Fee Related
- 1999-10-07 EP EP99954782A patent/EP1129217A4/en not_active Withdrawn
- 1999-10-07 AU AU11047/00A patent/AU776917B2/en not_active Expired
- 1999-10-07 CA CA002346765A patent/CA2346765A1/en not_active Abandoned
- 1999-10-07 WO PCT/US1999/023418 patent/WO2000019883A2/en not_active Application Discontinuation
- 1999-10-07 JP JP2000573246A patent/JP2003529315A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5506126A (en) * | 1988-02-25 | 1996-04-09 | The General Hospital Corporation | Rapid immunoselection cloning method |
US5338839A (en) * | 1988-04-12 | 1994-08-16 | Massachusetts Institute Of Technology | DNA encoding nestin protein |
US5629158A (en) * | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
WO1993006849A1 (en) * | 1991-10-03 | 1993-04-15 | The Center For Blood Research | Binding of plasmodium falciparum-infected erythrocytes to cd36 |
US5871931A (en) * | 1995-06-30 | 1999-02-16 | Millennium Pharmaceuticals, Inc. | Methods for detecting mammalian tub protein and RNA |
Non-Patent Citations (3)
Title |
---|
OHSHIMA ET AL.: "nucleotide sequence of the PR-1 gene of Nicotiana tabacum", FEBS LETTERS,, vol. 225, no. 1,2, 1987, pages 243 - 246, XP002928347 * |
See also references of EP1129217A4 * |
SILVERSTEIN ET AL.: "Sense and antisense cDNA transfection of CD36 (Glycoprotein IV) in melanoma cells", J. BIOL. CHEM.,, vol. 267, no. 23, 15 August 1992 (1992-08-15), pages 16607 - 16612, XP002928346 * |
Also Published As
Publication number | Publication date |
---|---|
AU776917B2 (en) | 2004-09-23 |
WO2000019883A9 (en) | 2000-10-19 |
AU1104700A (en) | 2000-04-26 |
CA2346765A1 (en) | 2000-04-13 |
US6322976B1 (en) | 2001-11-27 |
WO2000019883A2 (en) | 2000-04-13 |
EP1129217A2 (en) | 2001-09-05 |
EP1129217A4 (en) | 2005-04-20 |
JP2003529315A (en) | 2003-10-07 |
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