WO1999061653A3 - Light-mediated regional analysis of biologic material - Google Patents

Light-mediated regional analysis of biologic material Download PDF

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Publication number
WO1999061653A3
WO1999061653A3 PCT/US1999/011910 US9911910W WO9961653A3 WO 1999061653 A3 WO1999061653 A3 WO 1999061653A3 US 9911910 W US9911910 W US 9911910W WO 9961653 A3 WO9961653 A3 WO 9961653A3
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WO
WIPO (PCT)
Prior art keywords
biologic material
mediated
light
regional analysis
biologic
Prior art date
Application number
PCT/US1999/011910
Other languages
French (fr)
Other versions
WO1999061653A2 (en
Inventor
John A Zebala
Original Assignee
Syntrix Biochip
John A Zebala
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntrix Biochip, John A Zebala filed Critical Syntrix Biochip
Priority to AU42184/99A priority Critical patent/AU4218499A/en
Publication of WO1999061653A2 publication Critical patent/WO1999061653A2/en
Publication of WO1999061653A3 publication Critical patent/WO1999061653A3/en

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    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
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    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/30Phosphoric diester hydrolysing, i.e. nuclease
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    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486Metalloendopeptidases (3.4.24)
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03FPHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/26Processing photosensitive materials; Apparatus therefor
    • G03F7/40Treatment after imagewise removal, e.g. baking

Abstract

Compositions and methods are provided for performing regional analysis of biologic materials. The methods provided herein employ a photoresist layer that is established over a biologic material (which may be immobilized on a substrate). Regions of interest are selected and irradiated to expose specific regions of biologic material. Exposed biologic material may then be selectively analyzed using any of a variety of analytic methods.
PCT/US1999/011910 1998-05-27 1999-05-27 Light-mediated regional analysis of biologic material WO1999061653A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU42184/99A AU4218499A (en) 1998-05-27 1999-05-27 Light-mediated method and apparatus for the regional analysis of biologic material

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US8530298A 1998-05-27 1998-05-27
US09/085,302 1998-05-27
US11052798P 1998-12-01 1998-12-01
US11052898P 1998-12-01 1998-12-01
US11052998P 1998-12-01 1998-12-01
US60/110,528 1998-12-01
US60/110,527 1999-06-04
US60/110,529 1999-06-14

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WO1999061653A3 true WO1999061653A3 (en) 2000-04-20

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KR20010001577A (en) * 1999-06-07 2001-01-05 윤종용 Process for Preparing Oligopeptidenucleotide Probe Using Polymeric Photoacid Generator
ATE323113T1 (en) 1999-07-02 2006-04-15 Symyx Technologies Inc POLYMER BRANCHES FOR IMMOBILIZING MOLECULES ON SURFACES OR SUBSTRATES, WHICH THE POLYMERS HAVE WATER-SOLUBLE OR WATER-DISPERSIBLE SEGMENTS AND PROBE
AU2002246978A1 (en) 2001-01-10 2002-07-24 Symyx Technologies, Inc. Polymer brushes for immobilizing molecules to a surface
EP1243327A1 (en) * 2001-03-19 2002-09-25 BioChip Technologies GmbH Suface with a pattern of cells and method for its production
DE60315691D1 (en) * 2003-12-22 2007-09-27 Sgs Thomson Microelectronics Method of producing sensors with barriers of photoresist material
ES2949821T3 (en) 2004-01-07 2023-10-03 Illumina Cambridge Ltd Molecular arrays
EP1655069A1 (en) * 2004-08-05 2006-05-10 Solexa Limited Modified molecular arrays
IT1400874B1 (en) * 2010-07-05 2013-07-02 Univ Degli Studi Genova SUPPORT FLOOR WITH A ULTRA-FLAT SURFACE AND DEVICE FOR THE DETECTION OF ANTIGEN INCLUDING THE PLANAR SUPPORT.
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings

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EP0402718A1 (en) * 1989-06-03 1990-12-19 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Control of cell arrangement
JPH0440890A (en) * 1990-06-08 1992-02-12 Bio Material Kenkyusho:Kk Substrate to be used for culture of neurocyte
US5510270A (en) * 1989-06-07 1996-04-23 Affymax Technologies N.V. Synthesis and screening of immobilized oligonucleotide arrays

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US4415405A (en) * 1981-08-19 1983-11-15 Yale University Method for engraving a grid pattern on microscope slides and slips
EP0402718A1 (en) * 1989-06-03 1990-12-19 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Control of cell arrangement
US5510270A (en) * 1989-06-07 1996-04-23 Affymax Technologies N.V. Synthesis and screening of immobilized oligonucleotide arrays
JPH0440890A (en) * 1990-06-08 1992-02-12 Bio Material Kenkyusho:Kk Substrate to be used for culture of neurocyte

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