WO1999047163A2 - Mesenchymal stem cells for prevention and treatment of immune responses in transplantation - Google Patents
Mesenchymal stem cells for prevention and treatment of immune responses in transplantation Download PDFInfo
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- WO1999047163A2 WO1999047163A2 PCT/US1999/005548 US9905548W WO9947163A2 WO 1999047163 A2 WO1999047163 A2 WO 1999047163A2 US 9905548 W US9905548 W US 9905548W WO 9947163 A2 WO9947163 A2 WO 9947163A2
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- mesenchymal stem
- stem cells
- cells
- recipient
- transplant
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
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DE69929681T DE69929681T2 (en) | 1998-03-18 | 1999-03-12 | MESENCHYMAL STEM CELLS FOR THE PREVENTION AND TREATMENT OF IMMUNE RESPONSES IN TRANSPLANTATIONS |
EP99913876A EP1066052B1 (en) | 1998-03-18 | 1999-03-12 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
AU31856/99A AU755888B2 (en) | 1998-03-18 | 1999-03-12 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
CA002320040A CA2320040C (en) | 1998-03-18 | 1999-03-12 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
JP2000536402A JP4740452B2 (en) | 1998-03-18 | 1999-03-12 | Methods, compositions and methods of using mesenchymal stem cells for the prevention and treatment of immune responses in transplantation |
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US7846398P | 1998-03-18 | 1998-03-18 | |
US60/078,463 | 1998-03-18 | ||
US8996498P | 1998-06-19 | 1998-06-19 | |
US60/089,964 | 1998-06-19 |
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WO1999047163A2 true WO1999047163A2 (en) | 1999-09-23 |
WO1999047163A3 WO1999047163A3 (en) | 1999-11-18 |
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PCT/US1999/005548 WO1999047163A2 (en) | 1998-03-18 | 1999-03-12 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
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US (1) | US6328960B1 (en) |
EP (1) | EP1066052B1 (en) |
JP (1) | JP4740452B2 (en) |
AT (1) | ATE316795T1 (en) |
AU (1) | AU755888B2 (en) |
CA (1) | CA2320040C (en) |
DE (1) | DE69929681T2 (en) |
DK (1) | DK1066052T3 (en) |
ES (1) | ES2258329T3 (en) |
PT (1) | PT1066052E (en) |
WO (1) | WO1999047163A2 (en) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6281012B1 (en) * | 1999-10-12 | 2001-08-28 | Osiris Therapeutics, Inc. | Method of preparing suppressor T cells with allogeneic mesenchymal stem cells |
US6866842B1 (en) | 1998-05-01 | 2005-03-15 | University Of Pittsburgh | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction |
WO2006031539A2 (en) * | 2004-09-10 | 2006-03-23 | Cognate Therapeutics, Inc. | Liver stromal cells for prevention and treatment of immune responses in transplantation |
US7115417B1 (en) | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
EP1727892A1 (en) * | 2004-03-22 | 2006-12-06 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
EP1795588A1 (en) * | 2005-12-07 | 2007-06-13 | Cellerix, S.L. | Use of adipose tissue derived mesenchymal stem cells for the treatment of graft versus host disease |
EP1841322A1 (en) * | 2005-01-11 | 2007-10-10 | Cognate Therapeutics, Inc. | Bone marrow stromal cells for immunoprotection of transplanted neural stem cells |
WO2009031606A1 (en) | 2007-09-07 | 2009-03-12 | Jcr Pharmaceuticals Co., Ltd. | Therapeutic and prophylactic agents for arthritis |
WO2009073594A1 (en) * | 2007-11-30 | 2009-06-11 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
WO2009111030A1 (en) * | 2008-03-05 | 2009-09-11 | Osiris Therapeutics, Inc. | Use of mesenchymal stem cells for treating genetic diseases and disorders |
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DK1066052T3 (en) | 2006-06-12 |
CA2320040C (en) | 2007-05-22 |
ATE316795T1 (en) | 2006-02-15 |
EP1066052B1 (en) | 2006-02-01 |
AU3185699A (en) | 1999-10-11 |
WO1999047163A3 (en) | 1999-11-18 |
US6328960B1 (en) | 2001-12-11 |
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