WO1999023963A1 - Implant pour vertebre - Google Patents

Implant pour vertebre Download PDF

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Publication number
WO1999023963A1
WO1999023963A1 PCT/FR1998/002378 FR9802378W WO9923963A1 WO 1999023963 A1 WO1999023963 A1 WO 1999023963A1 FR 9802378 W FR9802378 W FR 9802378W WO 9923963 A1 WO9923963 A1 WO 9923963A1
Authority
WO
WIPO (PCT)
Prior art keywords
branches
implant according
branch
curvature
implant
Prior art date
Application number
PCT/FR1998/002378
Other languages
English (en)
Inventor
Jacques Senegas
Original Assignee
Dimso (Distribution Medicale Du Sud-Ouest)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dimso (Distribution Medicale Du Sud-Ouest) filed Critical Dimso (Distribution Medicale Du Sud-Ouest)
Priority to EP98955641A priority Critical patent/EP1030614B1/fr
Priority to JP2000520065A priority patent/JP2001522633A/ja
Priority to AU12411/99A priority patent/AU736014B2/en
Priority to DE1030614T priority patent/DE1030614T1/de
Priority to CA002310127A priority patent/CA2310127A1/fr
Priority to AT98955641T priority patent/ATE233520T1/de
Priority to DE69811933T priority patent/DE69811933T2/de
Priority to US09/554,015 priority patent/US6572617B1/en
Priority to KR1020007005103A priority patent/KR20010031993A/ko
Publication of WO1999023963A1 publication Critical patent/WO1999023963A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7071—Implants for expanding or repairing the vertebral arch or wedged between laminae or pedicles; Tools therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/82—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for bone cerclage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/842—Flexible wires, bands or straps

Definitions

  • the invention relates to cases of canal compression in the cervical spine.
  • Canal compression in the cervical vertebrae can occur due to trauma or malformation.
  • An object of the invention is to provide a device making it possible to respond to cases of canal compression.
  • an implant for the cervical vertebra comprising two branches adapted respectively to extend substantially along two cervical blades of the same cervical vertebra spaced from one another after osteotomy of the blades, and a rigid body connecting the two branches.
  • the branches of the implant can be fixed to the respective blades to keep them apart, which puts an end to the compression of the canal.
  • the implant comprises a deformable connection between the body and at least one of the branches.
  • the implant adapts appropriately to the morphology of the vertebra.
  • connection is elastically flexible.
  • the body comprises an area having a thickness less than a thickness of the rest of the body and defining the connection.
  • the body has a generally curved shape having a center of curvature located on the side of the branches.
  • the size of the implant is adapted to the shape of the canal.
  • the body has a curved internal face located opposite the branches and an external face opposite the branches, the internal face having a curvature having a center of curvature located on the side of the branches and a radius of curvature less than a radius of curvature of the outer face.
  • the shape of the implant saves the volume necessary for the canal.
  • At least one of the branches has reliefs.
  • the reliefs form a stop against movement along the branch, of connecting elements extending substantially perpendicular to a longitudinal direction of the branch.
  • the reliefs include notches.
  • the branches are able to be engaged in holes formed in the cervical blades, and the reliefs include teeth forming harpoons.
  • the branch has a width measured from the top of the teeth, decreasing towards a free end of the branch.
  • the reliefs extend over two longitudinal faces of the branch opposite one another.
  • FIG. 1 and Figure 2 are two elevational and side views of an implant according to a first embodiment of the invention
  • FIG. 3 is a view of the implant of Figure 1 installed on a vertebra
  • Figures 4 and 5 are two views similar to Figures 1 and 2 of an implant according to a second embodiment of the invention.
  • the implant 2 has the general shape of an elongated flat bar having two flat faces 4, 6 opposite one another and folded back to give it a configuration in "U” by delimiting two branches 8 and a body 10 connecting the two branches.
  • the bar is folded around two axes, corresponding to the folds, and parallel to the flat faces 4, 6 which can thus be called respectively internal and external faces.
  • the implant has an axis of symmetry 12 passing through the middle of the body 8.
  • the two branches 10 are inclined outward each in the direction opposite to this axis 12.
  • the body 8 and the two branches 10 have approximately the same length.
  • the body 8 has a generally curved shape having a center of curvature located on the axis 12 on the side of the branches 10.
  • An internal face 14 of the body has a radius of curvature less than a radius of curvature of an external face 16 of the body opposed to it.
  • the body 8 has two connecting zones 18 at the respective ends of the body, contiguous to the branches 10.
  • the two zones 18 are thinned by having a thickness less than a thickness of the rest of the body. They each constitute a flexible deformable connection flexible elastically between the body 8 and each branch 10. These thinned areas 18 are defined by a notch in the internal face 4 which makes it possible to provide a space for receiving the end of the blades of the vertebra.
  • Each branch 10 has two longitudinal edge faces 20, in which are formed pairs of notches 22, the notches of each pair extending on the respective faces 20 at the same level along the branch.
  • the pairs of notches 22 are for example three in number on each branch.
  • the notches 22 define between them teeth 23 with a flat top.
  • an osteotomy of the two cervical blades 24 of a cervical vertebra 26 is performed in order to open the cervical canal 28 delimited by the blades. Then the blades 24 are spread apart from one another towards the rear of the patient's body, for example until they are only given a slight inclination towards one another, which eliminates the compression of the channel 28.
  • each branch 10 is applied along a respective blade 24, on an external face of the blade opposite to the other blade.
  • Each branch 10 is attached to the associated blade 24 by strapping means 30 which may be cables or wires of implantable material. These means are received in the respective pairs of notches 22, which prohibits their sliding along the associated branch 10.
  • strapping means 30 which may be cables or wires of implantable material.
  • the body 8 has a length approximately equal to three times that of the branches 10.
  • the body 8 has a constant thickness over its entire length, identical to that of the branches 10. It is delimited by the two faces 4, 6 which are curved, concentric and of same radius of curvature.
  • Each branch 10 has notches 122 on its edge faces 20, defining pairs of teeth 123 with a pointed top.
  • Each tooth 123 has on the side of the free end of the branch 10 a face 124 inclined at an angle a with respect to the direction perpendicular to the longitudinal direction of the branch. The angle a is for example 60 °.
  • Each tooth 123 has on the side of the body 8 a face 126 perpendicular to the longitudinal direction of the branch.
  • the junction 125 between two faces 124, 126 of adjacent teeth 123 is curved.
  • the width 1 of the branch 10 corresponding to the distance between the tops of the teeth 123 of each pair is narrowed linearly from the end of the branch connected to the body to the free end of the branch.
  • the aligned vertices of the three teeth 123 of each face 20 define a line forming an angle b relative to the longitudinal direction of the branch 10. This angle b is for example 3 °.
  • the embodiment of FIGS. 4 and 5 advantageously applies to the case where the two branches 10 are engaged in holes made at an angle in the cervical blades, the teeth 123 forming harpoons making it possible to prevent said branches from separating from the blades leaving the aforementioned holes.

Abstract

L'implant (2) pour vertèbre cervicale (26) comporte deux branches (10) adaptées à respectivement s'étendre sensiblement le long de deux lames cervicales (24) d'une même vertèbre cervicale (26) écartées l'une de l'autre après ostéotomie des lames, et un corps rigide (8) reliant les deux branches (10).

Description

"IMPLANT POUR VERTEBRE". L'invention concerne les cas de compression canalaire au niveau du rachis cervical.
Une compression canalaire au niveau des vertèbres cervicales peut survenir du fait d'un traumatisme ou d'une malformation.
Un but de l'invention est de fournir un dispositif permettant de répondre aux cas de compression canalaire.
En vue de la réalisation de ce but, on prévoit selon l'invention un implant pour vertèbre cervicale comportant deux branches adaptées à respectivement s'étendre sensiblement le long de deux lames cervicales d'une même vertèbre cervicale écartées l'une de l'autre après ostéotomie des lames, et un corps rigide reliant les deux branches.
Ainsi, après ostéotomie des lames cervicales et écartement de celles-ci vers l'arrière, on peut fixer les branches de l'implant aux lames respectives pour les maintenir écartées, ce qui met fin à la compression du canal.
Avantageusement, l'implant comporte une liaison déformable entre le corps et au moins l'une des branches .
Ainsi, l'implant s'adapte convenablement à la morphologie de la vertèbre.
Avantageusement, la liaison est flexible élastiquement .
Avantageusement, le corps comporte une zone ayant une épaisseur inférieure à une épaisseur du reste du corps et définissant la liaison.
Avantageusement, le corps a une forme générale courbe ayant un centre de courbure situé du côté des branches . Ainsi, l'encombrement de l'implant est adapté à la forme du canal .
Avantageusement, le corps présente une face interne courbe située en regard des branches et une face externe opposée aux branches, la face interne présentant une courbure ayant un centre de courbure situé du côté des branches et un rayon de courbure inférieur à un rayon de courbure de la face externe.
Ici encore, la forme de l'implant ménage le volume nécessaire au canal.
Avantageusement, au moins l'une des branches présente des reliefs.
Avantageusement, les reliefs forment butée à l' encontre d'un déplacement le long de la branche, d'éléments de liaison s' étendant sensiblement perpendiculairement à une direction longitudinale de la branche .
Ainsi, on facilite la fixation des branches aux lames et on accroît la longévité de ces fixations. Avantageusement, les reliefs comprennent des encoches .
Avantageusement, les branches sont aptes à être engagées dans des trous formés dans les lames cervicales, et les reliefs comprennent des dents formant harpons.
Avantageusement, la branche présente une largeur mesurée à partir d'un sommet des dents, décroissante en direction d'une extrémité libre de la branche.
Avantageusement, les reliefs s'étendent sur deux faces longitudinales de la branche opposées l'une à l' autre .
D'autres caractéristiques et avantages de l'invention apparaîtront encore dans la description suivante de deux modes préférés de réalisation donnés à titre d'exemples non limitatifs. Aux dessins annexés :
- la figure 1 et la figure 2 sont deux vues en élévation et de côté d'un implant selon un premier mode de réalisation de l'invention ;
- la figure 3 est une vue de l'implant de la figure 1 installé sur une vertèbre ;
- les figures 4 et 5 sont deux vues analogues aux figures 1 et 2 d'un implant selon un deuxième mode de réalisation de l'invention.
En références aux figures 1 et 2, dans un premier mode de réalisation, l'implant 2 a une forme générale de barre allongée plate présentant deux faces planes 4, 6 opposées l'une à l'autre et repliée pour lui donner une configuration en « U » en délimitant deux branches 8 et un corps 10 reliant les deux branches. La barre est repliée autour de deux axes, correspondant aux plis, et parallèles aux faces planes 4, 6 qui peuvent ainsi être appelées respectivement faces interne et externe. L'implant présente un axe de symétrie 12 passant par le milieu du corps 8. Les deux branches 10 sont inclinées vers l'extérieur chacune en direction opposée à cet axe 12. Le corps 8 et les deux branches 10 ont environ la même longueur . Le corps 8 a une forme générale courbe ayant un centre de courbure situé sur l'axe 12 du côté des branches 10. Une face interne 14 du corps a un rayon de courbure inférieur à un rayon de courbure d'une face externe 16 du corps opposée à celle-ci. Le corps 8 présente deux zones de liaison 18 aux extrémités respectives du corps, contiguës aux branches 10. Les deux zones 18 sont amincies en présentant une épaisseur inférieure à une épaisseur du reste du corps. Elles constituent chacune une liaison souple déformable flexible élastiquement entre le corps 8 et chaque branche 10. Ces zones amincies 18 sont définies par une échancrure de la face interne 4 qui permet de ménager un espace pour la réception de l'extrémité des lames de la vertèbre.
Chaque branche 10 présente deux faces longitudinales de bord 20, dans lesquelles sont ménagées des paires d'encoches 22, les encoches de chaque paire s' étendant sur les faces 20 respectives à un même niveau le long de la branche. Les paires d'encoches 22 sont par exemple au nombre de trois sur chaque branche. Les encoches 22 définissent entre elles des dents 23 à sommet plat.
Pour utiliser l'implant, on pratique une ostéotomie des deux lames cervicales 24 d'une vertèbre cervicale 26 afin d'ouvrir le canal cervical 28 délimité par les lames. Puis on écarte les lames 24 l'une de l'autre vers l'arrière du corps du patient, par exemple jusqu'à leur donner seulement une légère inclinaison en direction l'une de l'autre, ce qui supprime la compression du canal 28.
On met en place l'implant 2. Pour cela, on applique chaque branche 10 le long d'une lame 24 respective, sur une face externe de la lame opposée à l'autre lame. On attache chaque branche 10 à la lame 24 associée par des moyens de cerclage 30 pouvant être des câbles ou des fils en matériau implantable. Ces moyens sont reçus dans les paires d'encoches respectives 22, ce qui interdit leur glissement le long de la branche 10 associée. Ainsi, on immobilise l'implant 2 sur son site d'implantation. L'implant permet de maintenir les lames 24 écartées l'une de l'autre.
En référence aux figures 4 et 5, dans un deuxième mode de réalisation de l'implant, le corps 8 a une longueur environ égale à trois fois celles des branches 10. De plus, le corps 8 a une épaisseur constante sur toute sa longueur, identique à celle des branches 10. Il est délimité par les deux faces 4, 6 qui sont courbes, concentriques et de même rayon de courbure.
Chaque branche 10 présente des encoches 122 sur ses faces de bord 20, définissant des paires de dents 123 à sommet pointu. Chaque dent 123 présente du côté de l'extrémité libre de la branche 10 une face 124 inclinée d'un angle a par rapport à la direction perpendiculaire à la direction longitudinale de la branche. L'angle a vaut par exemple 60°. Chaque dent 123 présente du côté du corps 8 une face 126 perpendiculaire à la direction longitudinale de la branche. Au fond de l'encoche 122, la jonction 125 entre deux faces 124, 126 de dents 123 adjacentes est courbe. De plus, la largeur 1 de la branche 10 correspondant à la distance entre les sommets des dents 123 de chaque paire va en se rétrécissant linéairement depuis l'extrémité de la branche reliée au corps jusqu'à l'extrémité libre de la branche. Les sommets alignés des trois dents 123 de chaque face 20 définissent une ligne formant un angle b par rapport à la direction longitudinale de la branche 10. Cet angle b vaut par exemple 3°. La forme de réalisation des figures 4 et 5 s'applique avantageusement au cas où les deux branches 10 sont engagées dans des trous pratiqués en biais dans les lames cervicales, les dents 123 formant des harpons permettant d'éviter que lesdites branches se séparent des lames en sortant des trous précités.

Claims

REVENDICATIONS
1. Implant (2) pour vertèbre cervicale (26), caractérisé en ce qu'il comporte deux branches (10) adaptées à respectivement s'étendre sensiblement le long de deux lames cervicales (24) d'une même vertèbre cervicale (26) écartées l'une de l'autre après ostéotomie des lames, et un corps rigide (8) reliant les deux branches (10) .
2. Implant selon la revendication 1, caractérisé en ce qu'il comporte une liaison déformable (18) entre le corps (8) et au moins l'une des branches (10) .
3. Implant selon la revendication 2, caractérisé en ce que la liaison (18) est flexible élastiquement .
4. Implant selon la revendication 2 ou 3, caractérisé en ce que le corps (8) comporte une zone (18) ayant une épaisseur inférieure à une épaisseur du reste du corps et définissant la liaison.
5. Implant selon l'une quelconques des revendications 1 à 4, caractérisé en ce que le corps (8) a une forme générale courbe ayant un centre de courbure situé du côté des branches (10) .
6. Implant selon l'une quelconque des revendications 1 à 5, caractérisé en ce que le corps (8) présente une face interne courbe (14) située en regard des branches (10) et une face externe (16) opposée aux branches, la face interne (14) présentant une courbure ayant un centre de courbure situé du côté des branches
(10) et un rayon de courbure inférieur à un rayon de courbure de la face externe (16) .
7. Implant selon l'une quelconque des revendications 1 à 6, caractérisé en ce qu'au moins l'une des branches (10) présente des reliefs (22, 23 ; 122, 123) .
8. Implant selon la revendication 7, caractérisé en ce que les reliefs (22, 23 ; 122, 123) forment butée à l' encontre d'un déplacement le long de la branche (10), d'éléments de liaison (30) s' étendant sensiblement perpendiculairement à une direction longitudinale de la branche .
9. Implant selon la revendication 8, caractérisé en ce que les reliefs comprennent des encoches (22 ; 122) .
10. Implant selon la revendication 7, caractérisé en ce que les branches (10) sont aptes à être engagées dans des trous pratiqués dans les lames cervicales, et en ce que les reliefs comprennent des dents (123) formant harpons.
11. Implant selon la revendication 10, caractérisé en ce que la branche (10) présente une largeur (1) mesurée à partir d'un sommet des dents (123), décroissante en direction d'une extrémité libre de la branche.
12. Implant selon l'une quelconque des revendications 7 à 11, caractérisé en ce que les reliefs s'étendent sur deux faces longitudinales (20) de la branche (10) opposées l'une à l'autre.
PCT/FR1998/002378 1997-11-10 1998-11-06 Implant pour vertebre WO1999023963A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EP98955641A EP1030614B1 (fr) 1997-11-10 1998-11-06 Implant pour vertebre
JP2000520065A JP2001522633A (ja) 1997-11-10 1998-11-06 椎骨用移植部材
AU12411/99A AU736014B2 (en) 1997-11-10 1998-11-06 Vertebral implant
DE1030614T DE1030614T1 (de) 1997-11-10 1998-11-06 Wirbelsäulenimplantat
CA002310127A CA2310127A1 (fr) 1997-11-10 1998-11-06 Implant pour vertebre
AT98955641T ATE233520T1 (de) 1997-11-10 1998-11-06 Wirbelsäulenimplantat
DE69811933T DE69811933T2 (de) 1997-11-10 1998-11-06 Wirbelsäulenimplantat
US09/554,015 US6572617B1 (en) 1997-11-10 1998-11-06 Vertebra implant
KR1020007005103A KR20010031993A (ko) 1997-11-10 1998-11-06 척추 이식장치

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714091A FR2770767B1 (fr) 1997-11-10 1997-11-10 Implant pour vertebre
FR97/14091 1997-11-10

Publications (1)

Publication Number Publication Date
WO1999023963A1 true WO1999023963A1 (fr) 1999-05-20

Family

ID=9513208

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1998/002378 WO1999023963A1 (fr) 1997-11-10 1998-11-06 Implant pour vertebre

Country Status (11)

Country Link
US (1) US6572617B1 (fr)
EP (1) EP1030614B1 (fr)
JP (1) JP2001522633A (fr)
KR (1) KR20010031993A (fr)
AT (1) ATE233520T1 (fr)
AU (1) AU736014B2 (fr)
CA (1) CA2310127A1 (fr)
DE (2) DE69811933T2 (fr)
ES (1) ES2152196T3 (fr)
FR (1) FR2770767B1 (fr)
WO (1) WO1999023963A1 (fr)

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US8066749B2 (en) 2004-12-13 2011-11-29 Warsaw Orthopedic, Inc. Implant for stabilizing a bone graft during spinal fusion
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US8118838B2 (en) 2004-12-13 2012-02-21 Kyphon Sarl Inter-cervical facet implant with multiple direction articulation joint and method for implanting
US8128660B2 (en) 2004-12-13 2012-03-06 Kyphon Sarl Inter-cervical facet joint implant with locking screw system
US8172877B2 (en) 2004-12-13 2012-05-08 Kyphon Sarl Inter-cervical facet implant with surface enhancements
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US8221461B2 (en) 2004-10-25 2012-07-17 Gmedelaware 2 Llc Crossbar spinal prosthesis having a modular design and systems for treating spinal pathologies
US8398681B2 (en) 2004-08-18 2013-03-19 Gmedelaware 2 Llc Adjacent level facet arthroplasty devices, spine stabilization systems, and methods
US8409254B2 (en) 2003-05-14 2013-04-02 Gmedelaware 2 Llc Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces
US8496686B2 (en) 2005-03-22 2013-07-30 Gmedelaware 2 Llc Minimally invasive spine restoration systems, devices, methods and kits
US8523907B2 (en) 2003-07-08 2013-09-03 Gmedelaware 2 Llc Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces
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US11457959B2 (en) 2019-05-22 2022-10-04 Spinal Elements, Inc. Bone tie and bone tie inserter
US11464552B2 (en) 2019-05-22 2022-10-11 Spinal Elements, Inc. Bone tie and bone tie inserter
US11304733B2 (en) 2020-02-14 2022-04-19 Spinal Elements, Inc. Bone tie methods

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Publication number Publication date
ES2152196T1 (es) 2001-02-01
ES2152196T3 (es) 2003-07-01
DE1030614T1 (de) 2001-05-23
US6572617B1 (en) 2003-06-03
FR2770767A1 (fr) 1999-05-14
AU736014B2 (en) 2001-07-26
KR20010031993A (ko) 2001-04-16
DE69811933T2 (de) 2003-11-27
JP2001522633A (ja) 2001-11-20
ATE233520T1 (de) 2003-03-15
EP1030614A1 (fr) 2000-08-30
DE69811933D1 (de) 2003-04-10
EP1030614B1 (fr) 2003-03-05
AU1241199A (en) 1999-05-31
FR2770767B1 (fr) 2000-03-10
CA2310127A1 (fr) 1999-05-20

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