WO1999021507A3 - Synthetic fibres for medical use and method of making the same - Google Patents

Synthetic fibres for medical use and method of making the same Download PDF

Info

Publication number
WO1999021507A3
WO1999021507A3 PCT/US1998/022810 US9822810W WO9921507A3 WO 1999021507 A3 WO1999021507 A3 WO 1999021507A3 US 9822810 W US9822810 W US 9822810W WO 9921507 A3 WO9921507 A3 WO 9921507A3
Authority
WO
WIPO (PCT)
Prior art keywords
fiber
cavities
medicament
component
extending
Prior art date
Application number
PCT/US1998/022810
Other languages
French (fr)
Other versions
WO1999021507A2 (en
Inventor
William R Baker
William H Hills
Arnold E Wilkie
Original Assignee
Hills Inc
William R Baker
William H Hills
Arnold E Wilkie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hills Inc, William R Baker, William H Hills, Arnold E Wilkie filed Critical Hills Inc
Priority to US09/530,183 priority Critical patent/US6551353B1/en
Priority to AU12824/99A priority patent/AU1282499A/en
Publication of WO1999021507A2 publication Critical patent/WO1999021507A2/en
Publication of WO1999021507A3 publication Critical patent/WO1999021507A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/24—Formation of filaments, threads, or the like with a hollow structure; Spinnerette packs therefor
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/28—Formation of filaments, threads, or the like while mixing different spinning solutions or melts during the spinning operation; Spinnerette packs therefor
    • D01D5/30—Conjugate filaments; Spinnerette packs therefor
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/28—Formation of filaments, threads, or the like while mixing different spinning solutions or melts during the spinning operation; Spinnerette packs therefor
    • D01D5/30—Conjugate filaments; Spinnerette packs therefor
    • D01D5/36—Matrix structure; Spinnerette packs therefor
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
    • D01F8/04—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
    • D01F8/04—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers
    • D01F8/12—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers with at least one polyamide as constituent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Abstract

A synthetic fiber is formed with a plurality of longitudinally-extending cavities (16, 54 and 64) which hold a medicament that is intended to be absorbed into tissue brought into contact with the fiber. The fiber can be formed by dissolving a soluble polymer component (14) of an extruded plural-component fiber (10), leaving cavities (16), that extend inward from the outer surface of the fiber in the locations of the dissolved polymer. After the fiber has been exposed to a solvent, the cavities left by the dissolved component are filled with a medicament (18). Specifically, the cavities are filled with a medicament that is mixed with a viscous carrier which solidifies within the cavities. The fibers can be used to make sutures, textile prostheses for insertion into the body, and epidermal pads and bandages. Fibers having internal cavities (64), i.e., cavities not extending to the external surface of the fiber, can be formed by extruding a single-component fiber (60) from a spinneret orifice (72) having a number of T-shaped slots extending from a central hub. A medicament is introduced into the internal cavities by soaking the fiber in a liquid containing the medicament. The internal-cavity fiber is therefore formed of polymer having some capability for liquid transport, e.g., nylon.
PCT/US1998/022810 1997-10-28 1998-10-28 Synthetic fibres for medical use and method of making the same WO1999021507A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US09/530,183 US6551353B1 (en) 1997-10-28 1998-10-28 Synthetic fibers for medical use and method of making the same
AU12824/99A AU1282499A (en) 1997-10-28 1998-10-28 Synthetic fibres for medical use and method of making the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6334597P 1997-10-28 1997-10-28
US60/063,345 1997-10-28

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09/530,183 A-371-Of-International US6551353B1 (en) 1997-10-28 1998-10-28 Synthetic fibers for medical use and method of making the same
US10/373,057 Division US20030138480A1 (en) 1997-10-28 2003-02-26 Synthetic fibers for medical use and method of making the same

Publications (2)

Publication Number Publication Date
WO1999021507A2 WO1999021507A2 (en) 1999-05-06
WO1999021507A3 true WO1999021507A3 (en) 1999-07-22

Family

ID=22048573

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/022810 WO1999021507A2 (en) 1997-10-28 1998-10-28 Synthetic fibres for medical use and method of making the same

Country Status (3)

Country Link
US (2) US6551353B1 (en)
AU (1) AU1282499A (en)
WO (1) WO1999021507A2 (en)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1289815B1 (en) * 1996-12-30 1998-10-16 Sorin Biomedica Cardio Spa ANGIOPLASTIC STENT AND RELATED PRODUCTION PROCESS
US6540780B1 (en) * 1998-11-23 2003-04-01 Medtronic, Inc. Porous synthetic vascular grafts with oriented ingrowth channels
US6207274B1 (en) 1999-12-21 2001-03-27 International Flavors & Fragrances Inc. Fragrance containing fiber
US6500444B1 (en) 1999-12-21 2002-12-31 International Flavors & Fragrances Inc. Continuously fragrance-emitting dry or wet wipe fabric article and method for preparing same
GB2357435A (en) * 1999-12-23 2001-06-27 Johnson & Johnson Medical Ltd Absorbent medicinal articles
EP1132058A1 (en) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravascular prothesis
US6979347B1 (en) * 2000-10-23 2005-12-27 Advanced Cardiovascular Systems, Inc. Implantable drug delivery prosthesis
US6758859B1 (en) * 2000-10-30 2004-07-06 Kenny L. Dang Increased drug-loading and reduced stress drug delivery device
DE60120955T3 (en) * 2001-07-20 2015-06-25 Cid S.P.A. stent
DE10150995A1 (en) * 2001-10-08 2003-04-10 Biotronik Mess & Therapieg Implant e.g. a stent, comprises a decomposable substance which allows contact between the cell proliferation inhibitor and the stent surroundings only after a specified time
US6861142B1 (en) * 2002-06-06 2005-03-01 Hills, Inc. Controlling the dissolution of dissolvable polymer components in plural component fibers
US20030236219A1 (en) * 2002-06-21 2003-12-25 Nightingale Stephen D. Edible product markers and methods for making and using edible product markers
NZ537729A (en) * 2002-06-21 2006-07-28 Stephen D Nightingale Multi-functional product markers and methods for making and using the same
US7135038B1 (en) * 2002-09-30 2006-11-14 Advanced Cardiovascular Systems, Inc. Drug eluting stent
US6991637B2 (en) * 2003-06-18 2006-01-31 Gore Enterprise Holdings, Inc. Soft tissue defect repair device
US7776101B2 (en) * 2003-06-18 2010-08-17 Gore Enterprise Holdings, Inc. Soft tissue defect repair device
US7687143B2 (en) * 2003-06-19 2010-03-30 Eastman Chemical Company Water-dispersible and multicomponent fibers from sulfopolyesters
US20040260034A1 (en) 2003-06-19 2004-12-23 Haile William Alston Water-dispersible fibers and fibrous articles
US7892993B2 (en) 2003-06-19 2011-02-22 Eastman Chemical Company Water-dispersible and multicomponent fibers from sulfopolyesters
US8513147B2 (en) 2003-06-19 2013-08-20 Eastman Chemical Company Nonwovens produced from multicomponent fibers
US20050133948A1 (en) * 2003-12-22 2005-06-23 Cook Michael C. Apparatus and method for multicomponent fibers
WO2006026397A2 (en) * 2004-08-26 2006-03-09 Stout Medical Group, L.P. Sutures and methods of making the same
CA2583867C (en) * 2004-10-18 2014-12-23 Frank J. Viola Adhesive suture structure and methods of using the same
EP1812920A1 (en) * 2004-10-29 2007-08-01 Adhesives Research, Inc. Microscopic tagging system for security identification
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US8361113B2 (en) 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US20060189993A1 (en) * 2004-11-09 2006-08-24 Arthrotek, Inc. Soft tissue conduit device
US7601165B2 (en) 2006-09-29 2009-10-13 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable suture loop
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US9468433B2 (en) 2006-02-03 2016-10-18 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US8562647B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US7737060B2 (en) * 2006-03-31 2010-06-15 Boston Scientific Scimed, Inc. Medical devices containing multi-component fibers
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (en) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド Medical device with selective covering
EP2063808A4 (en) * 2006-09-14 2012-06-13 Spineology Inc Absorbent fabric implant
US9918826B2 (en) 2006-09-29 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US20090169628A1 (en) 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
US8431149B2 (en) * 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US20080221618A1 (en) * 2007-03-09 2008-09-11 Gaoyuan Chen Co-extruded tissue grasping monofilament
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
JP2010535541A (en) * 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド Coating for medical devices with large surface area
US20090118821A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis with porous reservoir and non-polymer diffusion layer
US20090118812A1 (en) * 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9375327B2 (en) 2007-12-12 2016-06-28 Intact Vascular, Inc. Endovascular implant
US8128677B2 (en) 2007-12-12 2012-03-06 Intact Vascular LLC Device and method for tacking plaque to a blood vessel wall
US10166127B2 (en) 2007-12-12 2019-01-01 Intact Vascular, Inc. Endoluminal device and method
US9603730B2 (en) 2007-12-12 2017-03-28 Intact Vascular, Inc. Endoluminal device and method
US7896911B2 (en) 2007-12-12 2011-03-01 Innovasc Llc Device and method for tacking plaque to blood vessel wall
US10022250B2 (en) 2007-12-12 2018-07-17 Intact Vascular, Inc. Deployment device for placement of multiple intraluminal surgical staples
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) * 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US8449603B2 (en) * 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating
US20100078848A1 (en) * 2008-09-29 2010-04-01 Armark Authentication Technologies, Llc Spinneret and method of spinning fiber
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
US8512519B2 (en) 2009-04-24 2013-08-20 Eastman Chemical Company Sulfopolyesters for paper strength and process
WO2010132763A1 (en) * 2009-05-15 2010-11-18 Armark Authentication Technologies, Llc Fiber having non-uniform composition and method for making same
US8501644B2 (en) * 2009-06-02 2013-08-06 Christine W. Cole Activated protective fabric
US8968362B2 (en) 2010-04-08 2015-03-03 Covidien Lp Coated looped suture
US8616040B2 (en) * 2010-09-17 2013-12-31 Medtronic Vascular, Inc. Method of forming a drug-eluting medical device
US20120183861A1 (en) 2010-10-21 2012-07-19 Eastman Chemical Company Sulfopolyester binders
US10271973B2 (en) 2011-06-03 2019-04-30 Intact Vascular, Inc. Endovascular implant
US9096955B2 (en) 2011-09-30 2015-08-04 Ut-Battelle, Llc Method for the preparation of carbon fiber from polyolefin fiber precursor, and carbon fibers made thereby
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9357992B2 (en) 2011-11-10 2016-06-07 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
WO2013112768A1 (en) 2012-01-25 2013-08-01 Intact Vascular, Inc. Endoluminal device and method
US8882963B2 (en) 2012-01-31 2014-11-11 Eastman Chemical Company Processes to produce short cut microfibers
US9096959B2 (en) 2012-02-22 2015-08-04 Ut-Battelle, Llc Method for production of carbon nanofiber mat or carbon paper
US9597426B2 (en) 2013-01-25 2017-03-21 Covidien Lp Hydrogel filled barbed suture
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US9617685B2 (en) 2013-04-19 2017-04-11 Eastman Chemical Company Process for making paper and nonwoven articles comprising synthetic microfiber binders
JP6313450B2 (en) 2013-08-29 2018-04-18 テレフレックス メディカル インコーポレイテッド High strength multi-component suture
US9605126B2 (en) 2013-12-17 2017-03-28 Eastman Chemical Company Ultrafiltration process for the recovery of concentrated sulfopolyester dispersion
US9598802B2 (en) 2013-12-17 2017-03-21 Eastman Chemical Company Ultrafiltration process for producing a sulfopolyester concentrate
US9375336B1 (en) 2015-01-29 2016-06-28 Intact Vascular, Inc. Delivery device and method of delivery
US9433520B2 (en) 2015-01-29 2016-09-06 Intact Vascular, Inc. Delivery device and method of delivery
US10086116B2 (en) * 2015-08-31 2018-10-02 Ethicon Llc Adjunct material to provide controlled drug release
US10076324B2 (en) * 2015-08-31 2018-09-18 Ethicon Llc Adjunct material to provide controlled drug elution
US10569071B2 (en) 2015-08-31 2020-02-25 Ethicon Llc Medicant eluting adjuncts and methods of using medicant eluting adjuncts
US10993824B2 (en) 2016-01-01 2021-05-04 Intact Vascular, Inc. Delivery device and method of delivery
EP3532659A1 (en) 2016-10-26 2019-09-04 Association for the Advancement of Tissue Engineering and Cell based Technologies & Therapies (A4TEC) - Associação Fibers with segments, their preparation and applications thereof
US20180117819A1 (en) * 2016-10-27 2018-05-03 Clemson University Research Foundation Inherently super-omniphobic filaments, fibers, and fabrics and system for manufacture
US11660218B2 (en) 2017-07-26 2023-05-30 Intact Vascular, Inc. Delivery device and method of delivery
US20220090314A1 (en) * 2019-01-30 2022-03-24 Toray Industries, Inc. Water-repellent woven or knitted article, production method for same, and garment
JP7391524B2 (en) * 2019-03-29 2023-12-05 帝人フロンティア株式会社 Sea-island type composite fiber bundle and surface uneven fiber bundle made from the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5551954A (en) * 1991-10-04 1996-09-03 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US3991766A (en) 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
US3978203A (en) 1974-07-12 1976-08-31 Dynatech Corporation Sustained release of pharmaceuticals from polyester matrices
US4024871A (en) 1975-07-23 1977-05-24 Ethicon, Inc. Antimicrobial sutures
US4307723A (en) * 1978-04-07 1981-12-29 Medical Engineering Corporation Externally grooved ureteral stent
US4841968A (en) 1986-09-26 1989-06-27 Southern Research Institute Antithrombotic/thrombolytic suture and methods of making and using the same
US5162074A (en) * 1987-10-02 1992-11-10 Basf Corporation Method of making plural component fibers
DE68929425T2 (en) 1988-12-29 2003-06-05 Genzyme Corp Absorbable mixture for controlled release
US5010167A (en) 1989-03-31 1991-04-23 Massachusetts Institute Of Technology Poly(amide-and imide-co-anhydride) for biological application
JP2842905B2 (en) * 1989-12-01 1999-01-06 帝人株式会社 Multileaf cross section elastic filament
KR100198380B1 (en) * 1990-02-20 1999-06-15 데이비드 엠 모이어 Open capillary channel structures, improved process for making capillary channel structures, and extrusion die for use therein
US5545208A (en) * 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US6004346A (en) * 1990-02-28 1999-12-21 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5370681A (en) * 1991-09-16 1994-12-06 Atrium Medical Corporation Polyumenal implantable organ
US5411550A (en) * 1991-09-16 1995-05-02 Atrium Medical Corporation Implantable prosthetic device for the delivery of a bioactive material
US5716410A (en) * 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
US5891108A (en) * 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US6240616B1 (en) * 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6117802A (en) * 1997-10-29 2000-09-12 Alliedsignal Inc. Electrically conductive shaped fibers
US6206915B1 (en) * 1998-09-29 2001-03-27 Medtronic Ave, Inc. Drug storing and metering stent
US6465095B1 (en) * 2000-09-25 2002-10-15 Fiber Innovation Technology, Inc. Splittable multicomponent fibers with partially overlapping segments and methods of making and using the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5551954A (en) * 1991-10-04 1996-09-03 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent

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AU1282499A (en) 1999-05-17
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US6551353B1 (en) 2003-04-22

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