WO1999020394A3 - Spillproof microplate assembly - Google Patents

Spillproof microplate assembly Download PDF

Info

Publication number
WO1999020394A3
WO1999020394A3 PCT/US1998/019812 US9819812W WO9920394A3 WO 1999020394 A3 WO1999020394 A3 WO 1999020394A3 US 9819812 W US9819812 W US 9819812W WO 9920394 A3 WO9920394 A3 WO 9920394A3
Authority
WO
WIPO (PCT)
Prior art keywords
vent
well
microplate
wells
caps
Prior art date
Application number
PCT/US1998/019812
Other languages
French (fr)
Other versions
WO1999020394A2 (en
Inventor
David A Boulton
Carolyn I Solewski
Original Assignee
Texperts Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texperts Inc filed Critical Texperts Inc
Priority to AU95753/98A priority Critical patent/AU9575398A/en
Priority to EP98949427A priority patent/EP1023122A2/en
Priority to CA002306395A priority patent/CA2306395A1/en
Publication of WO1999020394A2 publication Critical patent/WO1999020394A2/en
Publication of WO1999020394A3 publication Critical patent/WO1999020394A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B01J2219/00335—Septa
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00423—Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B01J2219/00587—High throughput processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates

Abstract

A microplate assembly comprising a multi-well microplate, a plurality of vent caps and a porous vent film. Vent caps mount on the microplate to seal and vent the wells. When the vent caps are coupled to the wells, an interior volume is formed in each well. The wells function as a vessel for liquid samples, which remain within their predetermined spaces for all orientations of the microplate assembly. The vent cap comprises an array of well inserts. The well inserts are interconnected by a perforated web. The vents permit the pressure within the interior volume to be equalized with the ambient pressure. Material may be added to or removed from each well without removing the vent cap. The porous vent film, adheres to the vent caps while covering the passages, thereby inhibiting evaporation of the liquid samples.
PCT/US1998/019812 1997-10-17 1998-09-23 Spillproof microplate assembly WO1999020394A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU95753/98A AU9575398A (en) 1997-10-17 1998-09-23 Spillproof microplate assembly
EP98949427A EP1023122A2 (en) 1997-10-17 1998-09-23 Spillproof microplate assembly
CA002306395A CA2306395A1 (en) 1997-10-17 1998-09-23 Spillproof microplate assembly

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/953,441 US6027694A (en) 1996-10-17 1997-10-17 Spillproof microplate assembly
US08/953,441 1997-10-17

Publications (2)

Publication Number Publication Date
WO1999020394A2 WO1999020394A2 (en) 1999-04-29
WO1999020394A3 true WO1999020394A3 (en) 1999-07-29

Family

ID=25493998

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/019812 WO1999020394A2 (en) 1997-10-17 1998-09-23 Spillproof microplate assembly

Country Status (5)

Country Link
US (1) US6027694A (en)
EP (1) EP1023122A2 (en)
AU (1) AU9575398A (en)
CA (1) CA2306395A1 (en)
WO (1) WO1999020394A2 (en)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6193088B1 (en) * 1996-02-26 2001-02-27 Monty E. Vincent Flask vent and method of making same
US6500390B1 (en) * 1996-10-17 2002-12-31 David A. Boulton Method for sealing and venting a microplate assembly
ITPD980166A1 (en) * 1998-07-02 2000-01-02 Kaltek Srl CONTAINER OF LIQUIDS PARTICULARLY FOR ANALYSIS OF BIOLOGICAL LIQUIDS.
US6436351B1 (en) * 1998-07-15 2002-08-20 Deltagen Research Laboratories, L.L.C. Microtitre chemical reaction system
US6722054B2 (en) 1998-11-12 2004-04-20 Atrix Laboratories, Inc. Process and delivery container for lyophilizing active agent
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
CA2261326A1 (en) * 1999-02-09 2000-08-09 Jean-Pascal Viola Laboratory cap and well for hanging-drop crystallization methods
GB9906477D0 (en) * 1999-03-19 1999-05-12 Pyrosequencing Ab Liquid dispensing apparatus
US6241949B1 (en) * 1999-08-17 2001-06-05 Spectrumedix Corporation Spill-resistant microtitre trays and method of making
DE19963032A1 (en) 1999-12-24 2001-06-28 Roche Diagnostics Gmbh System for processing samples in a multi-chamber arrangement
DE20011397U1 (en) * 2000-06-29 2001-11-08 Gpc Biotech Ag Evaporation-reduced sample container and cover therefor
US7018589B1 (en) * 2000-07-19 2006-03-28 Symyx Technologies, Inc. High pressure parallel reactor
DE10041825A1 (en) 2000-08-25 2002-03-07 Invitek Gmbh Multiwell filtration plate and process for its manufacture
US20020106788A1 (en) * 2000-12-04 2002-08-08 Cawse James Norman Permeable reactor plate and method
US6896848B1 (en) 2000-12-19 2005-05-24 Tekcel, Inc. Microplate cover assembly
US20050047976A1 (en) * 2001-01-25 2005-03-03 Klaus Gubernator Method and apparatus for solid or solution phase reaction under ambient or inert conditions
US7118909B2 (en) * 2001-05-30 2006-10-10 Gevaert Matthew R Apparatus and method for biomaterial assay
US6896144B2 (en) * 2001-06-25 2005-05-24 Innovative Microplate Filtration and separation apparatus and method of assembly
US20030119060A1 (en) * 2001-08-10 2003-06-26 Desrosiers Peter J. Apparatuses and methods for creating and testing pre-formulations and systems for same
US20030044320A1 (en) * 2001-08-31 2003-03-06 Shun Luo High throughput screening micro array platform
WO2003061832A1 (en) * 2002-01-16 2003-07-31 Robbins Scientific Corporation Low volume micro-plate and volume-limiting plugs
US7036653B2 (en) 2002-01-29 2006-05-02 Siemens Technology-To-Business Center Llc Load manipulation system
US6910569B2 (en) 2002-01-29 2005-06-28 Siemens Technology-To-Business Center, Llc Load singulation system and method
US7122159B2 (en) * 2002-04-29 2006-10-17 Symyx Technologies, Inc. High pressure parallel reactor with individually sealable vessels
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7872804B2 (en) * 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7619819B2 (en) * 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7901630B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
ES2637439T3 (en) * 2002-08-20 2017-10-13 Becton, Dickinson And Company Method to collect a sample
US7441703B2 (en) * 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
US7959866B2 (en) * 2002-09-04 2011-06-14 Becton, Dickinson And Company Collection assembly
AU2003267192A1 (en) * 2002-09-12 2004-04-30 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
US20100255603A9 (en) * 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) * 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
EP1556297B1 (en) * 2002-10-29 2008-04-23 Siemens Aktiengesellschaft Conveyor system with distributed article manipulation
US7169602B2 (en) * 2002-12-04 2007-01-30 Applera Corporation Sample substrate for use in biological testing and method for filling a sample substrate
US7332348B2 (en) * 2003-02-28 2008-02-19 Applera Corporation Sample substrate having a divided sample chamber and method of loading thereof
US20040258563A1 (en) * 2003-06-23 2004-12-23 Applera Corporation Caps for sample wells and microcards for biological materials
US20050013743A1 (en) * 2003-07-18 2005-01-20 Edward Francis Farina I-shaped slit in a lidstock covering an array of aliquot vessels
US20060057729A1 (en) * 2003-09-12 2006-03-16 Illumina, Inc. Diffraction grating-based encoded element having a substance disposed thereon
US20050107909A1 (en) * 2003-11-14 2005-05-19 Siemens Technology-To-Business Center Llc Systems and methods for programming motion control
US20050065633A1 (en) * 2003-11-14 2005-03-24 Michael Wynblatt Systems and methods for relative control of load motion actuators
US20050107911A1 (en) * 2003-11-14 2005-05-19 Siemens Technology-To-Business Center Llc Systems and methods for controlling load motion actuators
US7433123B2 (en) * 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US20080135484A1 (en) * 2004-10-18 2008-06-12 Hammer Michael R Liquid Chromatography Apparatus
US7604173B2 (en) * 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
WO2006055735A2 (en) * 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
ATE459933T1 (en) * 2004-11-16 2010-03-15 Illumina Inc METHOD AND APPARATUS FOR READING CODED MICROBALLS
KR100612880B1 (en) * 2004-12-06 2006-08-14 삼성전자주식회사 Packing device for the sample loading hole of a chamber
US7854343B2 (en) * 2005-03-10 2010-12-21 Labcyte Inc. Fluid containers with reservoirs in their closures and methods of use
WO2006116616A2 (en) * 2005-04-26 2006-11-02 Applera Corporation Systems and methods for multiple analyte detection
US8066961B2 (en) * 2005-07-20 2011-11-29 Corning Incorporated Kinematic wellplate mounting method
US7623624B2 (en) * 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
US7830575B2 (en) * 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US7851204B2 (en) * 2006-06-09 2010-12-14 Pall Microreactor Technologies, Inc. Closure for milliliter scale bioreactor
US7807109B2 (en) 2007-05-14 2010-10-05 Freeslate, Inc. Parallel batch reactor with pressure monitoring
US20080286170A1 (en) * 2007-05-14 2008-11-20 Symyx Technologies, Inc. Parallel batch reactor
US7655191B2 (en) * 2007-05-14 2010-02-02 Symyx Solutions, Inc. Methods for chemical reactions in a parallel batch reactor
EP2030683B1 (en) 2007-08-17 2013-10-02 Qiagen GmbH Device and method for removing substances from pre-filled containers
US20090263892A1 (en) * 2008-04-18 2009-10-22 Henry Joseph Cattadoris Float valve for cell culture vessel
US8177082B2 (en) * 2008-04-18 2012-05-15 Corning Incorporated Flexible membrane valve for cell culture vessel
GB2472321B (en) 2009-07-31 2014-03-05 Oxley Hughes Ltd Means for improved liquid handling in a microplate
DE102009057223B4 (en) * 2009-12-05 2016-03-24 Chemagen Biopolymer-Technologie Aktiengesellschaft Sample vessel matrix and its production process
KR101499929B1 (en) * 2011-10-21 2015-03-06 셀 메디카 리미티드 Device for the aseptic expansion of cells
GB2504300A (en) * 2012-07-24 2014-01-29 Genevac Ltd Apparatus and method for evaporating a solvent from a sample
USD732187S1 (en) 2013-02-07 2015-06-16 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For An On Behalf Of Arizona State University Aliquot tray
KR102121852B1 (en) 2013-03-15 2020-06-12 벡톤 디킨슨 앤드 컴퍼니 Process tube and carrier tray
US10220392B2 (en) 2013-03-15 2019-03-05 Becton, Dickinson And Company Process tube and carrier tray
US11865544B2 (en) 2013-03-15 2024-01-09 Becton, Dickinson And Company Process tube and carrier tray
USD759835S1 (en) 2013-03-15 2016-06-21 Becton, Dickinson And Company Process tube strip
USD717468S1 (en) * 2013-06-24 2014-11-11 Bioptic, Inc. Microwell strip
US9885012B2 (en) * 2013-11-05 2018-02-06 Axion Biosystems, Inc. Devices, systems, and methods for targeted plating of materials in high-throughput culture plates
EP4220180A3 (en) * 2014-07-29 2023-08-16 Joachim Gerstel Arrangement for preparing a plurality of samples for an analytical method
USD804050S1 (en) * 2015-02-03 2017-11-28 ABgene Limited Combined polymerase chain reaction multi-well plate and plate of caps
CN107548416B (en) 2015-02-27 2021-07-13 康宁股份有限公司 Compliant cover for multi-well plate
WO2017087759A1 (en) * 2015-11-18 2017-05-26 President And Fellows Of Harvard College Cartridge-based system for long term culture of cell clusters
US10794632B2 (en) 2016-02-05 2020-10-06 Tolmar Therapeutics, Inc. Vented cover plate for an array of syringes
USD838004S1 (en) 2017-01-25 2019-01-08 Arizona Board Of Regents On Behalf Of Arizona State University Aliquot tray
USD841832S1 (en) 2017-02-17 2019-02-26 Arizona Board Of Regents On Behalf Of Arizona State University Aliquot tray
US10308568B2 (en) * 2017-05-01 2019-06-04 Chevron Phillips Chemical Company Lp Selective poisoning of aromatization catalysts to increase catalyst activity and selectivity
US10046322B1 (en) 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
USD908916S1 (en) 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
US20230226541A1 (en) * 2022-01-18 2023-07-20 Hollister Incorporated Fluid absorption test tube

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1109034A (en) * 1978-11-07 1981-09-15 Strathearn Wilson Apparatus for dispensing liquid into tubes
WO1992011939A1 (en) * 1991-01-11 1992-07-23 Emanuel Calenoff Device for in vitro testing
US5264184A (en) * 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
EP0627358A1 (en) * 1993-05-26 1994-12-07 Becton, Dickinson and Company Multiwell in-vitro fertilization plate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US86670A (en) * 1869-02-09 Improvement in ihkstands
US2627619A (en) * 1947-07-29 1953-02-10 Gagen Joseph Wilfrid Nail lacquer bottle assembly, including brush wiper
US4024857A (en) * 1974-12-23 1977-05-24 Becton, Dickinson And Company Micro blood collection device
US4073693A (en) * 1976-06-08 1978-02-14 American Home Products Corporation Apparatus and method for conducting a plurality of biological tests
US4070249A (en) * 1976-06-08 1978-01-24 American Home Products Corporation Apparatus for compensating for pressure within a biological test device
US4286637A (en) * 1978-11-09 1981-09-01 Connaught Laboratories Limited Apparatus for dispensing liquids into tubes
US4278437A (en) * 1979-04-09 1981-07-14 Jan Haggar Fluid specimen holder for biological fluid testing
US5429803A (en) * 1991-04-18 1995-07-04 Lamina, Inc. Liquid specimen container and attachable testing modules
US4885253A (en) * 1989-03-27 1989-12-05 Steris Corporation Universal biological indicator system
US5244635A (en) * 1992-06-19 1993-09-14 Cirrus Diagnostics, Inc. Centrifuge vessel with coaxial waste chamber having cap to prevent waste fluid transfer from the chamber into the vessel
AU7096496A (en) * 1995-09-28 1997-04-17 Kaken Pharmaceutical Co., Ltd. Process for the preparation of 4-methylenepiperidines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1109034A (en) * 1978-11-07 1981-09-15 Strathearn Wilson Apparatus for dispensing liquid into tubes
WO1992011939A1 (en) * 1991-01-11 1992-07-23 Emanuel Calenoff Device for in vitro testing
US5264184A (en) * 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
EP0627358A1 (en) * 1993-05-26 1994-12-07 Becton, Dickinson and Company Multiwell in-vitro fertilization plate

Also Published As

Publication number Publication date
AU9575398A (en) 1999-05-10
EP1023122A2 (en) 2000-08-02
CA2306395A1 (en) 1999-04-29
WO1999020394A2 (en) 1999-04-29
US6027694A (en) 2000-02-22

Similar Documents

Publication Publication Date Title
WO1999020394A3 (en) Spillproof microplate assembly
US6500390B1 (en) Method for sealing and venting a microplate assembly
CA2269442A1 (en) Storage container for analytical devices
US5516490A (en) Apparatus for preventing cross-contamination of multi-well test plates
WO2003016859A3 (en) Separation column having a photopolymerized sol-gel component and associated methods
WO2004011938A3 (en) Method and device for screening molecules in cells
KR970004111A (en) Waterproof Case Assembly for Storage Battery for Electronic Devices
WO2001064344A3 (en) Microfabricated devices for the storage and selective exposure of chemicals and devices
CA2643398A1 (en) Penetrable cap
CA2178883A1 (en) Ink container, manufacturing method therefor, ink jet cartridge and ink jet apparatus
WO2004020571A3 (en) Cell culture insert
WO2002026384A3 (en) Multi-well assay plate and plate holder and method of assembling the same
CA2357733A1 (en) Insecticide containing foam sheet
CA2242332A1 (en) Membrane module for a membrane separation system, its use and process for producing the same
EP1060024B1 (en) Closure plug array with blind bores
EP0744300A3 (en) Ink jet printer casing
PL349369A1 (en) A water vapour barrier and a method of making the same
WO2004061411A3 (en) Method and apparatus for mixing blood samples for cell analysis
EP1431052A3 (en) Voided polyester sheet for ink-jet recording materials
US5339865A (en) Apparatus for compensating for variations in pressure exerted by a fluid within a container against the container
GB2334954A (en) Array of connected closures
WO2007094314A1 (en) Container for transpiration
EP1066881A3 (en) Specimen collection assembly with cap
WO2004041709B1 (en) Drum vent
EP0974711A3 (en) Building element

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

ENP Entry into the national phase

Ref document number: 2306395

Country of ref document: CA

Ref country code: CA

Ref document number: 2306395

Kind code of ref document: A

Format of ref document f/p: F

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 1998949427

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1998949427

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1998949427

Country of ref document: EP