WO1998053311A3 - Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system - Google Patents
Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system Download PDFInfo
- Publication number
- WO1998053311A3 WO1998053311A3 PCT/US1998/010520 US9810520W WO9853311A3 WO 1998053311 A3 WO1998053311 A3 WO 1998053311A3 US 9810520 W US9810520 W US 9810520W WO 9853311 A3 WO9853311 A3 WO 9853311A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- platform
- microsystem
- fluid movement
- platforms
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01R—ELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
- H01R39/00—Rotary current collectors, distributors or interrupters
- H01R39/64—Devices for uninterrupted current collection
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/7172—Feed mechanisms characterised by the means for feeding the components to the mixer using capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K31/00—Actuating devices; Operating means; Releasing devices
- F16K31/002—Actuating devices; Operating means; Releasing devices actuated by temperature variation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/07—Centrifugal type cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01C—RESISTORS
- H01C17/00—Apparatus or processes specially adapted for manufacturing resistors
- H01C17/06—Apparatus or processes specially adapted for manufacturing resistors adapted for coating resistive material on a base
- H01C17/065—Apparatus or processes specially adapted for manufacturing resistors adapted for coating resistive material on a base by thick film techniques, e.g. serigraphy
- H01C17/06506—Precursor compositions therefor, e.g. pastes, inks, glass frits
- H01C17/06573—Precursor compositions therefor, e.g. pastes, inks, glass frits characterised by the permanent binder
- H01C17/06586—Precursor compositions therefor, e.g. pastes, inks, glass frits characterised by the permanent binder composed of organic material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/023—Sending and receiving of information, e.g. using bluetooth
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S366/00—Agitating
- Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S464/00—Rotary shafts, gudgeons, housings, and flexible couplings for rotary shafts
- Y10S464/90—Electrically insulative member
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/1624—Destructible or deformable element controlled
- Y10T137/1797—Heat destructible or fusible
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/1624—Destructible or deformable element controlled
- Y10T137/1797—Heat destructible or fusible
- Y10T137/1812—In fluid flow path
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/4456—With liquid valves or liquid trap seals
- Y10T137/4643—Liquid valves
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55068998A JP3469585B2 (en) | 1997-05-23 | 1998-05-22 | Apparatus and method for using centripetal acceleration to drive flow motion in microfluidics systems |
EP98923688A EP0983504A2 (en) | 1997-05-23 | 1998-05-22 | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
AU75919/98A AU7591998A (en) | 1997-05-23 | 1998-05-22 | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4748897P | 1997-05-23 | 1997-05-23 | |
US60/047,488 | 1997-05-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO1998053311A2 WO1998053311A2 (en) | 1998-11-26 |
WO1998053311A3 true WO1998053311A3 (en) | 1999-02-18 |
WO1998053311A9 WO1998053311A9 (en) | 1999-04-22 |
Family
ID=21949268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/010520 WO1998053311A2 (en) | 1997-05-23 | 1998-05-22 | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
Country Status (5)
Country | Link |
---|---|
US (6) | US6063589A (en) |
EP (1) | EP0983504A2 (en) |
JP (4) | JP3469585B2 (en) |
AU (1) | AU7591998A (en) |
WO (1) | WO1998053311A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9396752B2 (en) | 2005-08-05 | 2016-07-19 | Searete Llc | Memory device activation and deactivation |
Families Citing this family (465)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5960344A (en) * | 1993-12-20 | 1999-09-28 | Norand Corporation | Local area network having multiple channel wireless access |
US6048734A (en) * | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US6429007B1 (en) * | 1997-05-02 | 2002-08-06 | BIOMéRIEUX, INC. | Nucleic acid amplification reaction station for disposable test devices |
US6632399B1 (en) * | 1998-05-22 | 2003-10-14 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays |
JP3469585B2 (en) * | 1997-05-23 | 2003-11-25 | ガメラ バイオサイエンス コーポレイション | Apparatus and method for using centripetal acceleration to drive flow motion in microfluidics systems |
US7396508B1 (en) * | 2000-07-12 | 2008-07-08 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
US6572830B1 (en) | 1998-10-09 | 2003-06-03 | Motorola, Inc. | Integrated multilayered microfludic devices and methods for making the same |
SE0001779D0 (en) * | 2000-05-12 | 2000-05-12 | Gyros Ab | Microanalysis device |
US6503359B2 (en) | 1999-03-05 | 2003-01-07 | Burstein Technologies, Inc. | Monomolecular adhesion methods for manufacturing microfabricated multilaminate devices |
ATE357656T1 (en) * | 1999-04-06 | 2007-04-15 | Univ Alabama Res Found | DEVICE FOR SCREENING CRYSTALIZATION CONDITIONS IN CRYSTAL GROWING SOLUTIONS |
WO2000069560A1 (en) * | 1999-05-14 | 2000-11-23 | Gamera Bioscience Corporation | A centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids |
US7332326B1 (en) | 1999-05-14 | 2008-02-19 | Tecan Trading Ag | Centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids |
SE516321C2 (en) * | 1999-05-31 | 2001-12-17 | Gambro Inc | Centrifuge for the treatment of blood and blood components |
JP2004529312A (en) * | 1999-06-18 | 2004-09-24 | ガメラ バイオサイエンス コーポレイション | Devices and methods for miniaturized homogeneous assays |
US6706519B1 (en) | 1999-06-22 | 2004-03-16 | Tecan Trading Ag | Devices and methods for the performance of miniaturized in vitro amplification assays |
ATE395136T1 (en) * | 1999-06-22 | 2008-05-15 | Tecan Trading Ag | DEVICES FOR PERFORMING MINIATURIZED IN VITRO AMPLIFICATION ASSAY |
JP3990910B2 (en) * | 1999-07-16 | 2007-10-17 | アプレラ コーポレイション | High density electrophoresis device and method |
US7088650B1 (en) | 1999-08-23 | 2006-08-08 | Worthington Mark O | Methods and apparatus for optical disc data acquisition using physical synchronization markers |
US6888951B1 (en) | 1999-08-23 | 2005-05-03 | Nagaoka & Co., Ltd. | Methods and apparatus for analyzing operational and analyte data acquired from optical disc |
US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
US6875619B2 (en) * | 1999-11-12 | 2005-04-05 | Motorola, Inc. | Microfluidic devices comprising biochannels |
US7169298B2 (en) * | 2000-01-26 | 2007-01-30 | Transgenomic, Inc. | Method and apparatus for separating polynucleotides using monolithic capillary columns |
JP2003533681A (en) | 2000-05-15 | 2003-11-11 | テカン・トレーディング・アクチェンゲゼルシャフト | Microfluidic device and method for performing cell-based analysis |
AU2001261657A1 (en) * | 2000-05-15 | 2001-11-26 | Tecan Trading Ag | Use of vapor-deposited conformal coatings in microfluidic structures |
US20020151078A1 (en) * | 2000-05-15 | 2002-10-17 | Kellogg Gregory J. | Microfluidics devices and methods for high throughput screening |
WO2002000347A2 (en) * | 2000-06-28 | 2002-01-03 | 3M Innovative Properties Company | Sample processing devices, systems and methods |
US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
US6720187B2 (en) | 2000-06-28 | 2004-04-13 | 3M Innovative Properties Company | Multi-format sample processing devices |
AU2001273156A1 (en) * | 2000-07-03 | 2002-01-14 | Xeotron Corporation | Devices and methods for carrying out chemical reactions using photogenerated reagents |
ES2323124T3 (en) * | 2000-07-21 | 2009-07-07 | Senzime Ab (Publ.) | A MICRO-CALORIMETER DEVICE. |
FR2812306B1 (en) * | 2000-07-28 | 2005-01-14 | Gabriel Festoc | POLYMERSIS CHAIN AMPLIFICATION SYSTEM OF TARGET NUCLEIC SEQUENCES |
US6561479B1 (en) * | 2000-08-23 | 2003-05-13 | Micron Technology, Inc. | Small scale actuators and methods for their formation and use |
US6939451B2 (en) * | 2000-09-19 | 2005-09-06 | Aclara Biosciences, Inc. | Microfluidic chip having integrated electrodes |
US6855553B1 (en) | 2000-10-02 | 2005-02-15 | 3M Innovative Properties Company | Sample processing apparatus, methods and systems |
US6854386B2 (en) * | 2000-10-31 | 2005-02-15 | International Imaging Materials Inc. | Ceramic decal assembly |
US6796733B2 (en) | 2000-10-31 | 2004-09-28 | International Imaging Materials Inc. | Thermal transfer ribbon with frosting ink layer |
US6990904B2 (en) * | 2000-10-31 | 2006-01-31 | International Imaging Materials, Inc | Thermal transfer assembly for ceramic imaging |
US8097471B2 (en) * | 2000-11-10 | 2012-01-17 | 3M Innovative Properties Company | Sample processing devices |
WO2002041004A2 (en) | 2000-11-16 | 2002-05-23 | Burstein Technologies, Inc. | Optical biodiscs with reflective layers |
WO2002044695A1 (en) * | 2000-11-16 | 2002-06-06 | Burstein Technologies, Inc. | Methods and apparatus for detecting and quantifying lymphocytes with optical biodiscs |
US7026131B2 (en) * | 2000-11-17 | 2006-04-11 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-discs |
US7087203B2 (en) * | 2000-11-17 | 2006-08-08 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-disc |
AU2002239289A1 (en) * | 2000-11-22 | 2002-06-03 | Burstein Technologies, Inc. | Apparatus and methods for separating agglutinants and disperse particles |
US6521188B1 (en) * | 2000-11-22 | 2003-02-18 | Industrial Technology Research Institute | Microfluidic actuator |
SE0004296D0 (en) * | 2000-11-23 | 2000-11-23 | Gyros Ab | Device and method for the controlled heating in micro channel systems |
SE0004297D0 (en) * | 2000-11-23 | 2000-11-23 | Gyros Ab | Device for thermal cycling |
SE0004351D0 (en) * | 2000-11-27 | 2000-11-27 | Helen Andersson | System and method for time-controlled liquid handling for reactions and processes in a microfluidic flow cell system |
US20020076354A1 (en) * | 2000-12-01 | 2002-06-20 | Cohen David Samuel | Apparatus and methods for separating components of particulate suspension |
US7079468B2 (en) | 2000-12-08 | 2006-07-18 | Burstein Technologies, Inc. | Optical discs for measuring analytes |
US7054258B2 (en) | 2000-12-08 | 2006-05-30 | Nagaoka & Co., Ltd. | Optical disc assemblies for performing assays |
US7091034B2 (en) | 2000-12-15 | 2006-08-15 | Burstein Technologies, Inc. | Detection system for disk-based laboratory and improved optical bio-disc including same |
WO2002051537A2 (en) * | 2000-12-22 | 2002-07-04 | Burstein Technologies, Inc. | Optical bio-discs and methods relating thereto |
US6770434B2 (en) * | 2000-12-29 | 2004-08-03 | The Provost, Fellows And Scholars Of The College Of The Holy & Undivided Trinity Of Queen Elizabeth Near Dublin | Biological assay method |
WO2002059596A2 (en) * | 2001-01-02 | 2002-08-01 | President And Fellows Of Harvard College | Method and apparatus for measurement of the sulfate concentration in air samples |
US20040099310A1 (en) * | 2001-01-05 | 2004-05-27 | Per Andersson | Microfluidic device |
US6653625B2 (en) * | 2001-03-19 | 2003-11-25 | Gyros Ab | Microfluidic system (MS) |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US6717136B2 (en) | 2001-03-19 | 2004-04-06 | Gyros Ab | Microfludic system (EDI) |
EP1386343B1 (en) * | 2001-03-19 | 2012-10-24 | Gyros Patent Ab | A microfluidic system for energy desorption / ionisation mass spectrometry |
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
EP1384076B1 (en) * | 2001-03-19 | 2012-07-25 | Gyros Patent Ab | Characterization of reaction variables |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US6852287B2 (en) * | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US6806088B2 (en) * | 2001-04-09 | 2004-10-19 | Matsushita Electric Industrial Co., Ltd. | Method and apparatus for improving the performance of microanalytic and microsynthetic procedures |
EP1493014A2 (en) | 2001-04-11 | 2005-01-05 | Burstein Technologies, Inc. | Multi-parameter assays including analysis discs and methods relating thereto |
WO2004058405A1 (en) * | 2001-05-02 | 2004-07-15 | 3M Innovative Properties Company | Sample processing device with resealable process chamber |
US6805841B2 (en) | 2001-05-09 | 2004-10-19 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Liquid pumping system |
DE10123259A1 (en) * | 2001-05-12 | 2002-11-21 | Eppendorf Ag | Microfluidic storage and / or dosing component |
EP1409998A4 (en) * | 2001-06-09 | 2007-07-11 | Glsynthesis Inc | Lipid structures and uses thereof |
US7141416B2 (en) * | 2001-07-12 | 2006-11-28 | Burstein Technologies, Inc. | Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith |
WO2003009107A2 (en) * | 2001-07-20 | 2003-01-30 | Burstein Technologies, Inc. | Optical analysis disc and related drive assembly for performing interactive centrifugation |
WO2003027723A2 (en) * | 2001-07-24 | 2003-04-03 | Burstein Technologies, Inc. | Method and apparatus for bonded fluidic circuit for optical bio-disc |
US6825127B2 (en) | 2001-07-24 | 2004-11-30 | Zarlink Semiconductor Inc. | Micro-fluidic devices |
EP1483052B1 (en) | 2001-08-28 | 2010-12-22 | Gyros Patent Ab | Retaining microfluidic microcavity and other microfluidic structures |
SE0104077D0 (en) * | 2001-10-21 | 2001-12-05 | Gyros Ab | A method and instrumentation for micro dispensation of droplets |
US6919058B2 (en) * | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
US20030129665A1 (en) * | 2001-08-30 | 2003-07-10 | Selvan Gowri Pyapali | Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems |
US20030143637A1 (en) * | 2001-08-31 | 2003-07-31 | Selvan Gowri Pyapali | Capture layer assemblies for cellular assays including related optical analysis discs and methods |
AU2002335715A1 (en) * | 2001-09-07 | 2003-03-24 | Burstein Technologies, Inc. | Optical bio-disc systems for nuclear morphology based identification |
DE60237289D1 (en) | 2001-09-17 | 2010-09-23 | Gyros Patent Ab | A CONTROLLED POWER IN A MICROFLUID DEVICE ENABLING FUNCTION UNIT |
US7338760B2 (en) * | 2001-10-26 | 2008-03-04 | Ntu Ventures Private Limited | Sample preparation integrated chip |
EP2287330A1 (en) * | 2001-11-01 | 2011-02-23 | Rensselaer Polytechnic Institute | Biocatalytic Solgel Microarrays |
US20030175947A1 (en) * | 2001-11-05 | 2003-09-18 | Liu Robin Hui | Enhanced mixing in microfluidic devices |
US7157049B2 (en) * | 2001-11-20 | 2007-01-02 | Nagaoka & Co., Ltd. | Optical bio-discs and fluidic circuits for analysis of cells and methods relating thereto |
GB0128350D0 (en) | 2001-11-27 | 2002-01-16 | Lab901 Ltd | Non-rigid apparatus for microfluidic applications |
WO2003052427A1 (en) * | 2001-12-14 | 2003-06-26 | Arkray, Inc. | Sample measuring device |
US6716395B2 (en) * | 2001-12-18 | 2004-04-06 | Serenex, Inc. | Integrated protein affinity capture centrifugation device |
US7244393B2 (en) | 2001-12-21 | 2007-07-17 | Kimberly-Clark Worldwide, Inc. | Diagnostic device and system |
US6889468B2 (en) * | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
AU2002219551A1 (en) * | 2001-12-28 | 2003-07-30 | Hitachi High-Technologies Corporation | Extractor, chemical analyzer, and chemical analyzing method |
US6532997B1 (en) | 2001-12-28 | 2003-03-18 | 3M Innovative Properties Company | Sample processing device with integral electrophoresis channels |
EP1461414B1 (en) * | 2001-12-31 | 2009-04-22 | The Provost Fellows and Scholars of the College of the Holy Undivided Trinity of Queen Elizabeth Near Dublin | Assembly for cell-based assays |
WO2003065354A2 (en) * | 2002-01-31 | 2003-08-07 | Burstein Technologies, Inc. | Manufacturing processes for making optical analysis discs including successive patterning operations and optical discs thereby manufactured |
US20040241381A1 (en) * | 2002-01-31 | 2004-12-02 | Chen Yihfar | Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs |
WO2003065355A2 (en) * | 2002-01-31 | 2003-08-07 | Burstein Technologies, Inc. | Bio-safety features for optical analysis disc and disc system including same |
US20050170490A1 (en) * | 2002-01-31 | 2005-08-04 | Chen Yihfar | Processes for manufacturing optical analysis discs with molded microfluidic structures and discs made according thereto |
US20050176059A1 (en) * | 2002-01-31 | 2005-08-11 | Pal Andrew A. | Bio-safe dispenser and optical analysis disc assembly |
WO2003068857A1 (en) * | 2002-02-15 | 2003-08-21 | Bridgestone Corporation | Rubber composition and pneumatic tire made therefrom |
JP3933058B2 (en) * | 2002-02-25 | 2007-06-20 | 日立化成工業株式会社 | Support unit for microfluidic system and method for manufacturing the same |
US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
US7419821B2 (en) * | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
ITVE20020012A1 (en) * | 2002-03-13 | 2003-09-15 | Alper Srl | ELECTRIC DEANANT OR INSECTICIDE EMANATOR. |
US20030180965A1 (en) * | 2002-03-25 | 2003-09-25 | Levent Yobas | Micro-fluidic device and method of manufacturing and using the same |
JP2005532043A (en) * | 2002-04-11 | 2005-10-27 | シークエノム, インコーポレイテッド | Method and apparatus for performing chemical reactions on a solid support |
AU2003235970A1 (en) * | 2002-04-30 | 2003-11-17 | Arkray, Inc. | Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument |
US7384602B2 (en) | 2002-05-08 | 2008-06-10 | Hitachi High-Technologies Corporation | Chemical analysis apparatus and genetic diagnostic apparatus |
WO2003096008A1 (en) * | 2002-05-08 | 2003-11-20 | Hitachi High-Technologies Corporation | Chemical analyzer and gene diagnosing apparatus |
JP4095886B2 (en) * | 2002-05-08 | 2008-06-04 | 株式会社日立ハイテクノロジーズ | Chemical analysis device and genetic diagnosis device |
US20050106714A1 (en) * | 2002-06-05 | 2005-05-19 | Zarur Andrey J. | Rotatable reactor systems and methods |
US7005265B1 (en) | 2002-06-20 | 2006-02-28 | Wenhong Fan | Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays |
JP4106977B2 (en) | 2002-06-21 | 2008-06-25 | 株式会社日立製作所 | Analysis chip and analyzer |
US7018545B2 (en) * | 2002-07-22 | 2006-03-28 | Matsushita Electric Industrial Co., Ltd. | Component separating device, method of manufacturing the device, and method of separating fine solid component by using the device |
US20040011650A1 (en) * | 2002-07-22 | 2004-01-22 | Frederic Zenhausern | Method and apparatus for manipulating polarizable analytes via dielectrophoresis |
US7198759B2 (en) * | 2002-07-26 | 2007-04-03 | Applera Corporation | Microfluidic devices, methods, and systems |
US7135147B2 (en) * | 2002-07-26 | 2006-11-14 | Applera Corporation | Closing blade for deformable valve in a microfluidic device and method |
US7201881B2 (en) * | 2002-07-26 | 2007-04-10 | Applera Corporation | Actuator for deformable valves in a microfluidic device, and method |
US7442515B2 (en) * | 2002-07-30 | 2008-10-28 | University Of Washington | Apparatus and methods for binding molecules and cells |
EP1391237B1 (en) * | 2002-08-01 | 2011-09-21 | Tosoh Corporation | Fine channel device, desksize chemical plant and fine particle producing apparatus employing them |
TW590982B (en) * | 2002-09-27 | 2004-06-11 | Agnitio Science & Technology I | Micro-fluid driving device |
KR100444751B1 (en) * | 2002-11-11 | 2004-08-16 | 한국전자통신연구원 | Device of Controlling Fluid using Surface Tension |
US7152616B2 (en) * | 2002-12-04 | 2006-12-26 | Spinx, Inc. | Devices and methods for programmable microscale manipulation of fluids |
US7285255B2 (en) * | 2002-12-10 | 2007-10-23 | Ecolab Inc. | Deodorizing and sanitizing employing a wicking device |
US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
US7094354B2 (en) * | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
US7507376B2 (en) * | 2002-12-19 | 2009-03-24 | 3M Innovative Properties Company | Integrated sample processing devices |
US7476361B2 (en) * | 2002-12-24 | 2009-01-13 | Tecan Trading Ag | Microfluidics devices and methods of diluting samples and reagents |
US7332129B2 (en) * | 2003-01-09 | 2008-02-19 | 3M Innovative Properties Company | Sample processing device having process chambers with bypass slots |
DE10302721A1 (en) * | 2003-01-23 | 2004-08-05 | Steag Microparts Gmbh | Microfluidic arrangement for dosing liquids |
WO2004067444A1 (en) | 2003-01-30 | 2004-08-12 | Gyros Ab | Inner walls of microfluidic devices |
KR100959101B1 (en) * | 2003-02-20 | 2010-05-25 | 삼성전자주식회사 | Polymerase chain reaction device and method for regulating opening or shutting of inlet and outlet of PCR device |
CN101044404A (en) * | 2003-03-03 | 2007-09-26 | 长冈实业株式会社 | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
US7060225B2 (en) * | 2003-03-20 | 2006-06-13 | Northeastern Ohio Universities College Of Medicine | Self-contained assay device for rapid detection of biohazardous agents |
SE0300822D0 (en) | 2003-03-23 | 2003-03-23 | Gyros Ab | A collection of Micro Scale Devices |
SE0300823D0 (en) | 2003-03-23 | 2003-03-23 | Gyros Ab | Preloaded Microscale Devices |
JP3888632B2 (en) * | 2003-03-26 | 2007-03-07 | 靖浩 堀池 | Micromixer, sample analysis kit and manufacturing method thereof |
WO2004095034A1 (en) * | 2003-04-23 | 2004-11-04 | Nagaoka & Co., Ltd. | Optical bio-discs including spiral fluidic circuits for performing assays |
US8309039B2 (en) * | 2003-05-14 | 2012-11-13 | James Russell Webster | Valve structure for consistent valve operation of a miniaturized fluid delivery and analysis system |
US7435381B2 (en) * | 2003-05-29 | 2008-10-14 | Siemens Healthcare Diagnostics Inc. | Packaging of microfluidic devices |
JP4151483B2 (en) * | 2003-06-10 | 2008-09-17 | ソニー株式会社 | Bioassay substrate and bioassay apparatus and method |
US7736889B2 (en) * | 2003-06-10 | 2010-06-15 | The United States Of America As Represented By The Secretary Of The Navy | Fluidic force discrimination |
FR2856046B1 (en) * | 2003-06-16 | 2005-07-29 | Biomerieux Sa | FLUIDIC MICROVANNE WITH OPENING BY ELECTRICAL CONTROL |
EP1656203A2 (en) * | 2003-06-19 | 2006-05-17 | Nagaoka & Co., Ltd. | Fluidic circuits for sample preparation including bio-discs and methods relating thereto |
US7390464B2 (en) | 2003-06-19 | 2008-06-24 | Burstein Technologies, Inc. | Fluidic circuits for sample preparation including bio-discs and methods relating thereto |
US20080257754A1 (en) * | 2003-06-27 | 2008-10-23 | Pugia Michael J | Method and apparatus for entry of specimens into a microfluidic device |
US20040265172A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method and apparatus for entry and storage of specimens into a microfluidic device |
WO2005001429A2 (en) * | 2003-06-27 | 2005-01-06 | Nagaoka & Co., Ltd. | Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays |
US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
US7238269B2 (en) * | 2003-07-01 | 2007-07-03 | 3M Innovative Properties Company | Sample processing device with unvented channel |
WO2005009581A2 (en) * | 2003-07-15 | 2005-02-03 | Nagaoka & Co. Ltd. | Methods and apparatus for blood separation and analysis using membranes on an optical bio-disc |
JP2007500351A (en) * | 2003-07-25 | 2007-01-11 | 長岡実業株式会社 | Fluid circuit for sample preparation with biodisc and related method |
JP4996248B2 (en) | 2003-07-31 | 2012-08-08 | ハンディーラブ インコーポレイテッド | Processing of particle-containing samples |
JPWO2005012916A1 (en) * | 2003-08-05 | 2006-09-21 | 太陽誘電株式会社 | Sample analyzer and disk-shaped sample analysis medium |
US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
EP1508373A3 (en) * | 2003-08-19 | 2005-08-03 | Herbener, Heinz-Gerd | Sample carrier with channel for liquids |
JP3959436B2 (en) * | 2003-08-29 | 2007-08-15 | 独立行政法人物質・材料研究機構 | Flow fluctuation structure and micromixer |
WO2005027593A1 (en) * | 2003-09-12 | 2005-03-24 | Ngk Insulators, Ltd. | Plasma producing electrode and plasma reactor |
EP1673167A2 (en) * | 2003-09-15 | 2006-06-28 | Tecan Trading AG | Microfluidics devices and methods for performing cell based assays |
US7296592B2 (en) * | 2003-09-16 | 2007-11-20 | Eksigent Technologies, Llc | Composite polymer microfluidic control device |
CN1864058B (en) * | 2003-10-03 | 2012-07-18 | 独立行政法人物质·材料研究机构 | Chip using method and test chip |
JP4391790B2 (en) * | 2003-10-03 | 2009-12-24 | 独立行政法人物質・材料研究機構 | Chip usage and inspection chip |
WO2005036182A1 (en) | 2003-10-15 | 2005-04-21 | Matsushita Electric Industrial Co., Ltd. | Method of passing fluid in capillary chip |
GB0327094D0 (en) * | 2003-11-21 | 2003-12-24 | Inverness Medical Switzerland | Laminated device |
US7196295B2 (en) * | 2003-11-21 | 2007-03-27 | Watlow Electric Manufacturing Company | Two-wire layered heater system |
US7329391B2 (en) * | 2003-12-08 | 2008-02-12 | Applera Corporation | Microfluidic device and material manipulating method using same |
US20050130177A1 (en) * | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7837947B2 (en) * | 2003-12-12 | 2010-11-23 | 3M Innovative Properties Company | Sample mixing on a microfluidic device |
US7322254B2 (en) * | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
DE10359160A1 (en) * | 2003-12-16 | 2005-07-21 | Roche Diagnostics Gmbh | Test element for the examination of sample material |
US20050142571A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using solid phase material |
US7939249B2 (en) * | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
US20050142570A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent |
JP4750412B2 (en) * | 2003-12-25 | 2011-08-17 | モレックス インコーポレイテド | Biologically derived molecules, dioxins and endocrine disrupting substance detection apparatus and detection method using the apparatus |
US20090050620A1 (en) * | 2004-01-06 | 2009-02-26 | Gyros Ab | Contact heating arrangement |
US8592219B2 (en) | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
SE0400181D0 (en) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
WO2005084792A1 (en) * | 2004-02-18 | 2005-09-15 | Hitachi Chemical Co., Ltd. | Supporting unit for micro fluid system |
JP4482926B2 (en) * | 2004-02-20 | 2010-06-16 | 富士フイルム株式会社 | Scientific phenomenon evaluation apparatus, diffusion velocity measurement experimental apparatus, and manufacturing method thereof |
US20070095393A1 (en) * | 2004-03-30 | 2007-05-03 | Piero Zucchelli | Devices and methods for programmable microscale manipulation of fluids |
US7056473B2 (en) * | 2004-04-29 | 2006-06-06 | Response Biomedical Corp. | Method and apparatus of quantitative assays |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
AU2005241080B2 (en) | 2004-05-03 | 2011-08-11 | Handylab, Inc. | Processing polynucleotide-containing samples |
US7491363B2 (en) * | 2004-07-15 | 2009-02-17 | Applied Biosystems, Llc. | Fluid processing device |
US7932090B2 (en) * | 2004-08-05 | 2011-04-26 | 3M Innovative Properties Company | Sample processing device positioning apparatus and methods |
US20090087859A1 (en) * | 2004-09-20 | 2009-04-02 | Johnson Brandon T | Microfluidic device for detecting soluble molecules |
DE102004046396A1 (en) * | 2004-09-24 | 2006-04-13 | Land Baden-Württemberg, vertreten durch das Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg, vertreten durch den Minister | A particle sedimentation apparatus and method for performing a particle sedimentation |
EP1795899B1 (en) * | 2004-09-30 | 2012-06-06 | ARKRAY, Inc. | Analytical instrument with film heater |
WO2006044843A2 (en) * | 2004-10-18 | 2006-04-27 | Applera Corporation | A device including a dissolvable structure for flow control |
US7361315B2 (en) * | 2004-10-26 | 2008-04-22 | Konica Minolta Medical & Graphic, Inc. | Micro-reactor for biological substance inspection and biological substance inspection device |
MX2007005364A (en) * | 2004-11-03 | 2008-01-22 | Third Wave Tech Inc | Single step detection assay. |
JP4054798B2 (en) | 2004-11-29 | 2008-03-05 | キヤノン株式会社 | Fluid transfer method |
EP1832861B1 (en) * | 2004-11-30 | 2020-04-29 | Hitachi Chemical Company, Ltd. | Analytical pretreatment device |
WO2006062191A1 (en) * | 2004-12-09 | 2006-06-15 | Hitachi Chemical Co., Ltd. | Support unit for micro fluid system and process for producing the same |
JP2008534914A (en) | 2005-01-17 | 2008-08-28 | ユィロス・パテント・アクチボラグ | Multipurpose channel |
JP4646204B2 (en) * | 2005-01-27 | 2011-03-09 | ブラザー工業株式会社 | Receiving target, sorting device, and sorting method |
WO2006080140A1 (en) | 2005-01-28 | 2006-08-03 | Matsushita Electric Industrial Co., Ltd. | Blood treatment apparatus and blood supply method |
KR100647320B1 (en) * | 2005-02-05 | 2006-11-23 | 삼성전자주식회사 | Microsystem for separating serum from blood |
WO2006093845A2 (en) * | 2005-02-28 | 2006-09-08 | Careside Medical Llc | A micro-fluidic fluid separation device and method |
US7754151B2 (en) | 2005-04-04 | 2010-07-13 | Panasonic Corporation | Liquid homogenizer and analyzer employing the same |
WO2006108559A2 (en) * | 2005-04-09 | 2006-10-19 | Boehringer Ingelheim Microparts Gmbh | Device and method for analyzing a sample liquid |
JP5139263B2 (en) * | 2005-04-14 | 2013-02-06 | ギロス・パテント・エービー | Liquid plug |
JP4927817B2 (en) * | 2005-04-14 | 2012-05-09 | ギロス・パテント・エービー | Microfluidic device with multiple valves |
WO2006110097A1 (en) * | 2005-04-14 | 2006-10-19 | Gyros Patent Ab | Separation structure |
WO2006110094A1 (en) * | 2005-04-14 | 2006-10-19 | Gyros Patent Ab | Upward microconduits |
JP5139264B2 (en) * | 2005-04-14 | 2013-02-06 | ギロス・パテント・エービー | Microfluidic device with finger valve |
US7668069B2 (en) * | 2005-05-09 | 2010-02-23 | Searete Llc | Limited use memory device with associated information |
US8462605B2 (en) | 2005-05-09 | 2013-06-11 | The Invention Science Fund I, Llc | Method of manufacturing a limited use data storing device |
US7770028B2 (en) | 2005-09-09 | 2010-08-03 | Invention Science Fund 1, Llc | Limited use data storing device |
US8140745B2 (en) | 2005-09-09 | 2012-03-20 | The Invention Science Fund I, Llc | Data retrieval methods |
US7916592B2 (en) * | 2005-05-09 | 2011-03-29 | The Invention Science Fund I, Llc | Fluid mediated disk activation and deactivation mechanisms |
US7512959B2 (en) * | 2005-05-09 | 2009-03-31 | Searete Llc | Rotation responsive disk activation and deactivation mechanisms |
US7748012B2 (en) | 2005-05-09 | 2010-06-29 | Searete Llc | Method of manufacturing a limited use data storing device |
US8218262B2 (en) | 2005-05-09 | 2012-07-10 | The Invention Science Fund I, Llc | Method of manufacturing a limited use data storing device including structured data and primary and secondary read-support information |
US8220014B2 (en) | 2005-05-09 | 2012-07-10 | The Invention Science Fund I, Llc | Modifiable memory devices having limited expected lifetime |
US7907486B2 (en) | 2006-06-20 | 2011-03-15 | The Invention Science Fund I, Llc | Rotation responsive disk activation and deactivation mechanisms |
US7694316B2 (en) * | 2005-05-09 | 2010-04-06 | The Invention Science Fund I, Llc | Fluid mediated disk activation and deactivation mechanisms |
US8159925B2 (en) | 2005-08-05 | 2012-04-17 | The Invention Science Fund I, Llc | Limited use memory device with associated information |
US7596073B2 (en) * | 2005-05-09 | 2009-09-29 | Searete Llc | Method and system for fluid mediated disk activation and deactivation |
US7916615B2 (en) | 2005-06-09 | 2011-03-29 | The Invention Science Fund I, Llc | Method and system for rotational control of data storage devices |
US7668068B2 (en) | 2005-06-09 | 2010-02-23 | Searete Llc | Rotation responsive disk activation and deactivation mechanisms |
US8121016B2 (en) | 2005-05-09 | 2012-02-21 | The Invention Science Fund I, Llc | Rotation responsive disk activation and deactivation mechanisms |
US8099608B2 (en) | 2005-05-09 | 2012-01-17 | The Invention Science Fund I, Llc | Limited use data storing device |
US7565596B2 (en) | 2005-09-09 | 2009-07-21 | Searete Llc | Data recovery systems |
US20060263265A1 (en) * | 2005-05-23 | 2006-11-23 | Der-Ren Kang | Blood micro-separator |
US8226908B2 (en) * | 2005-06-03 | 2012-07-24 | Spinx, Inc. | Dosimeter for programmable microscale manipulation of fluids |
US20060281192A1 (en) * | 2005-06-13 | 2006-12-14 | Harding Philip H | Method for mixing fluids in microfluidic systems |
US7935318B2 (en) * | 2005-06-13 | 2011-05-03 | Hewlett-Packard Development Company, L.P. | Microfluidic centrifugation systems |
US9279818B2 (en) * | 2005-06-28 | 2016-03-08 | Samsung Electronics Co., Ltd. | Bio drive apparatus, and assay method using the same |
US7437914B2 (en) * | 2005-06-28 | 2008-10-21 | Hewlett-Packard Development Company, L.P. | Microfluidic test systems with gas bubble reduction |
US7323660B2 (en) | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
US7763210B2 (en) * | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
JP4546889B2 (en) * | 2005-07-08 | 2010-09-22 | ローム株式会社 | Chip with weighing unit |
JP4619224B2 (en) * | 2005-07-27 | 2011-01-26 | パナソニック株式会社 | Rotational analysis device |
US20070031282A1 (en) * | 2005-08-04 | 2007-02-08 | Piero Zucchelli | Devices and methods for interfacing microfluidic devices with fluid handling devices |
US20070031293A1 (en) * | 2005-08-04 | 2007-02-08 | Beatty Christopher C | Method and apparatus for collecting and diluting a liquid sample |
US7731910B2 (en) * | 2005-08-05 | 2010-06-08 | Hewlett-Packard Development Company, L.P. | Microfluidic mixing assembly |
US7791728B2 (en) * | 2005-08-11 | 2010-09-07 | Hewlett-Packard Development Company, L.P. | System for optically analyzing a substance with a selected single-wavelength |
JP4802925B2 (en) * | 2005-08-19 | 2011-10-26 | パナソニック株式会社 | Analytical device and analytical apparatus using the same |
JP4973800B2 (en) * | 2005-08-19 | 2012-07-11 | パナソニック株式会社 | Analytical device and analytical apparatus using the same |
JP2007098223A (en) * | 2005-09-30 | 2007-04-19 | Fujifilm Corp | Fluid operation method of chemical device |
US8123834B2 (en) | 2005-10-06 | 2012-02-28 | The Board Of Trustees Of The University Of Illinois | High gain selective metal organic framework preconcentrators |
JP4531677B2 (en) * | 2005-10-24 | 2010-08-25 | パナソニック株式会社 | Assay method, sensor device for implementing the same, and measuring device for sensor device |
US8172455B2 (en) * | 2005-10-28 | 2012-05-08 | Arkray, Inc. | Liquid feeding method and cartridge to be used therein |
US7534618B2 (en) | 2005-10-28 | 2009-05-19 | Hewlett-Packard Development Company, L.P. | Systems and methods for measuring glycated hemoglobin |
WO2007052647A1 (en) * | 2005-11-01 | 2007-05-10 | Matsushita Electric Industrial Co., Ltd. | Disc for analyzing liquid sample and method of analyzing mixed liquid sample |
JPWO2007052648A1 (en) * | 2005-11-02 | 2009-04-30 | パナソニック株式会社 | Sample analysis disc |
EP1946830B1 (en) * | 2005-11-07 | 2019-04-03 | Konica Minolta Medical & Graphic, Inc. | Microreactor |
JP4331158B2 (en) * | 2005-11-15 | 2009-09-16 | シャープ株式会社 | Blade cleaning jig |
US20070113908A1 (en) * | 2005-11-18 | 2007-05-24 | The Ohio State University And Bioloc, Inc. | Valve for microfluidic chips |
EP2032984A1 (en) | 2005-12-12 | 2009-03-11 | Gyros Patent Ab | Microfluidic assays and microfluidic devices |
JP4749867B2 (en) | 2006-01-13 | 2011-08-17 | パナソニック株式会社 | Electrophoresis device |
EP1987362A2 (en) * | 2006-02-10 | 2008-11-05 | Boehringer Ingelheim microParts GmbH | Device and method for treating or cleaning sample material, in particular nucleic acids |
TWI272464B (en) * | 2006-03-01 | 2007-02-01 | Instr Technology Res Ct Nat Ap | Fluid order controlling apparatus and method |
US7651869B2 (en) * | 2006-03-14 | 2010-01-26 | Research International, Inc. | Optical assay apparatus and methods |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
DK2001990T3 (en) | 2006-03-24 | 2016-10-03 | Handylab Inc | Integrated microfluidic sample processing system and method for its use |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US8088616B2 (en) | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
US20070224591A1 (en) * | 2006-03-27 | 2007-09-27 | General Electric Company | Rotation-based microsampler, system and method of using the same |
KR100763922B1 (en) * | 2006-04-04 | 2007-10-05 | 삼성전자주식회사 | Valve unit and apparatus with the same |
US7998433B2 (en) * | 2006-04-04 | 2011-08-16 | Samsung Electronics Co., Ltd. | Valve unit and apparatus having the same |
JP4754394B2 (en) | 2006-04-14 | 2011-08-24 | ローム株式会社 | Microchip |
KR100738113B1 (en) * | 2006-05-10 | 2007-07-12 | 삼성전자주식회사 | Phase transition type valve and the manufacturing method thereof |
US8137626B2 (en) * | 2006-05-19 | 2012-03-20 | California Institute Of Technology | Fluorescence detector, filter device and related methods |
US8432777B2 (en) | 2006-06-19 | 2013-04-30 | The Invention Science Fund I, Llc | Method and system for fluid mediated disk activation and deactivation |
US8264928B2 (en) | 2006-06-19 | 2012-09-11 | The Invention Science Fund I, Llc | Method and system for fluid mediated disk activation and deactivation |
WO2008016271A1 (en) * | 2006-08-02 | 2008-02-07 | Jae Chern Yoo | Thin film chemical analysis apparatus and analysis method using the same |
EP1884284A1 (en) * | 2006-08-04 | 2008-02-06 | Samsung Electronics Co., Ltd. | Closing valve unit and reaction apparatus having closing valve |
US8464760B2 (en) * | 2006-08-16 | 2013-06-18 | Samsung Electronic Co., Ltd. | Valve unit, reaction apparatus with the same, and method of forming valve in channel |
KR100818274B1 (en) | 2006-09-05 | 2008-04-01 | 삼성전자주식회사 | Apparatus and method of controlling the microfluidic system, and the microfluidic system |
US8273310B2 (en) * | 2006-09-05 | 2012-09-25 | Samsung Electronics Co., Ltd. | Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device |
KR101343034B1 (en) | 2006-09-05 | 2013-12-18 | 삼성전자 주식회사 | Centrifugal microfluidic device for target protein detection and microfluidic system comprising the same |
US7951333B2 (en) * | 2006-09-05 | 2011-05-31 | Samsung Electronics Co., Ltd. | Centrifugal force-based microfluidic device for protein detection and microfluidic system including the same |
KR100851980B1 (en) * | 2006-09-05 | 2008-08-12 | 삼성전자주식회사 | Centrifugal force based microfluidic device having heat-activative unit, microfluidic system comprinsing the same and method for driving the system |
US8187541B2 (en) | 2006-09-18 | 2012-05-29 | California Institute Of Technology | Apparatus for detecting target molecules and related methods |
US8709787B2 (en) | 2006-11-14 | 2014-04-29 | Handylab, Inc. | Microfluidic cartridge and method of using same |
US8307988B2 (en) * | 2006-12-11 | 2012-11-13 | Samsung Electronics Co., Ltd. | Apparatus and method for separating components |
US7857141B2 (en) * | 2006-12-11 | 2010-12-28 | Samsung Electronics Co., Ltd. | Apparatus and method for separating components |
KR100818290B1 (en) * | 2006-12-11 | 2008-03-31 | 삼성전자주식회사 | Component separating apparatus and method |
EP2117713B1 (en) | 2006-12-22 | 2019-08-07 | DiaSorin S.p.A. | Thermal transfer methods for microfluidic systems |
CA2673056A1 (en) | 2006-12-22 | 2008-07-03 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
WO2008096492A1 (en) * | 2007-02-05 | 2008-08-14 | Shimadzu Corporation | Reaction container plate and reaction processing method |
WO2008098094A1 (en) * | 2007-02-06 | 2008-08-14 | Network Biosystems, Inc. | Devices and methods for the performance of miniaturized in vitro assays |
KR101305976B1 (en) * | 2007-02-12 | 2013-09-12 | 삼성전자주식회사 | Centrifugal force based microfluidic device for serial dilution and microfluidic system comprising the same |
US20110284394A1 (en) * | 2007-02-14 | 2011-11-24 | The Board of Trustees of the University Illinois Office Technology | Portable Electrochemical Multiphase Microreactor for Sensing Trace Chemical Vapors |
JP4816791B2 (en) * | 2007-03-02 | 2011-11-16 | 株式会社島津製作所 | Reaction vessel plate and reaction processing apparatus |
US7799656B2 (en) | 2007-03-15 | 2010-09-21 | Dalsa Semiconductor Inc. | Microchannels for BioMEMS devices |
KR100883658B1 (en) | 2007-04-02 | 2009-02-18 | 삼성전자주식회사 | Centrifugal force-based microfluidic device and microfluidic system including the same |
WO2008124104A1 (en) | 2007-04-04 | 2008-10-16 | Network Biosystems Inc. | Integrated nucleic acid analysis |
US8168444B2 (en) * | 2007-04-09 | 2012-05-01 | Panasonic Corporation | Substrate having channel portion including chambers, and method of transferring liquid by using the substrate |
US8580575B2 (en) | 2007-04-13 | 2013-11-12 | Shimadzu Corporation | Reactor plate and reaction processing method |
WO2008132872A1 (en) * | 2007-04-13 | 2008-11-06 | Shimadzu Corporation | Reaction container plate and reaction processing method |
JP4947141B2 (en) * | 2007-04-13 | 2012-06-06 | 株式会社島津製作所 | Reaction vessel plate and reaction processing method |
KR100858091B1 (en) * | 2007-04-24 | 2008-09-10 | 삼성전자주식회사 | Centrifugal force-based microfluidic device having sample distribution structure and microfluidic system including the microfluidic device |
US20100129878A1 (en) * | 2007-04-25 | 2010-05-27 | Parthasarathy Ranjani V | Methods for nucleic acid amplification |
KR101258434B1 (en) | 2007-05-03 | 2013-05-02 | 삼성전자주식회사 | Microfluidic system and fabricating method of the same |
US8124030B2 (en) * | 2007-05-08 | 2012-02-28 | The Regents Of The University Of California | Microfluidic device having regulated fluid transfer between elements located therein |
JP4918589B2 (en) | 2007-05-10 | 2012-04-18 | パナソニック株式会社 | Substrate including flow path part having chamber, and multistage liquid feeding apparatus including the same |
US7980272B2 (en) * | 2007-06-21 | 2011-07-19 | Samsung Electronics Co., Ltd. | Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve |
EP2175889A1 (en) * | 2007-07-02 | 2010-04-21 | CaridianBCT Biotechnologies, LLC | Apparatus for photo reduction of contaminants in blood and blood products with calibration means |
WO2009008128A1 (en) * | 2007-07-06 | 2009-01-15 | Panasonic Corporation | Pumping apparatus and pumping method |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
US8324372B2 (en) | 2007-07-13 | 2012-12-04 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8415140B2 (en) * | 2007-10-04 | 2013-04-09 | Panasonic Corporation | Analysis device, and analysis apparatus and method using the same |
JP5013423B2 (en) * | 2007-10-18 | 2012-08-29 | ローム株式会社 | Microchip |
US8381169B2 (en) * | 2007-10-30 | 2013-02-19 | International Business Machines Corporation | Extending unified process and method content to include dynamic and collaborative content |
TWI362491B (en) * | 2007-11-02 | 2012-04-21 | Ind Tech Res Inst | Fluid analytical device and fluid analytical method thereof |
WO2009060617A1 (en) * | 2007-11-08 | 2009-05-14 | Panasonic Corporation | Analyzing device and analyzing method using same |
SE531873C2 (en) * | 2007-11-12 | 2009-09-01 | Lifeassays Ab | Device for biochemical processing and analysis of sample liquid |
WO2009066897A2 (en) * | 2007-11-22 | 2009-05-28 | Jae Chern Yoo | Thin film valve device and its controlling apparatus |
CN101450336B (en) * | 2007-12-06 | 2012-02-08 | 财团法人工业技术研究院 | Fluid separation method and device |
EP2072131B1 (en) | 2007-12-13 | 2015-04-22 | Roche Diagnostics GmbH | Microfluid element for mixing a fluid into a reagent |
JP4872923B2 (en) * | 2008-01-07 | 2012-02-08 | 株式会社島津製作所 | Reaction vessel |
JP4872922B2 (en) * | 2008-01-07 | 2012-02-08 | 株式会社島津製作所 | Reaction vessel |
JP4872921B2 (en) * | 2008-01-07 | 2012-02-08 | 株式会社島津製作所 | Reaction vessel |
DE102008003979B3 (en) * | 2008-01-11 | 2009-06-10 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Fluidic device, fluidic module and method for handling a fluid |
US8123841B2 (en) | 2008-01-16 | 2012-02-28 | The Board Of Trustees Of The University Of Illinois | Column design for micro gas chromatograph |
US8969070B2 (en) * | 2008-01-21 | 2015-03-03 | Samsung Electronics Co., Ltd. | Thin-film layered centrifuge device and analysis method using the same |
WO2009099512A2 (en) * | 2008-02-04 | 2009-08-13 | Micropoint Biosciences, Inc. | Centrifugal fluid analyzer rotor |
US8632243B2 (en) * | 2008-03-10 | 2014-01-21 | The Hong Kong Polytechnic University | Microfluidic mixing using continuous acceleration/deceleration methodology |
US8735846B1 (en) | 2008-03-14 | 2014-05-27 | Advanced Technology Applications, Llc | Electromagnetic biosensor |
US7812318B1 (en) | 2008-03-14 | 2010-10-12 | Advanced Technology Applications, Llc | Electromagnetic biosensor |
US7854893B2 (en) * | 2008-03-28 | 2010-12-21 | Panasonic Corporation | Analysis device and an analysis apparatus using the analysis device |
KR100919400B1 (en) * | 2008-04-07 | 2009-09-29 | 삼성전자주식회사 | Microfluidic device and method for fabricating the same |
US8269029B2 (en) | 2008-04-08 | 2012-09-18 | The Board Of Trustees Of The University Of Illinois | Water repellent metal-organic frameworks, process for making and uses regarding same |
WO2009136600A1 (en) | 2008-05-09 | 2009-11-12 | コニカミノルタエムジー株式会社 | Microchip, microchip liquid supply system, and microchip liquid supply method |
KR100955481B1 (en) | 2008-05-14 | 2010-04-30 | 삼성전자주식회사 | Valve unit, microfluidic device with the same, and method for fabricating the valve unit |
KR100960066B1 (en) * | 2008-05-14 | 2010-05-31 | 삼성전자주식회사 | Microfluidic device containing lyophilized reagent therein and analysing method using the same |
TWI385383B (en) | 2008-05-28 | 2013-02-11 | Ind Tech Res Inst | Analytical system, and analytical method and flowing structure thereof |
JP5239552B2 (en) * | 2008-06-26 | 2013-07-17 | 株式会社島津製作所 | Reaction vessel plate and reaction processing method |
USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
KR20100007809A (en) * | 2008-07-14 | 2010-01-22 | 삼성전자주식회사 | Microfluidic device, sample analyzing method using the same, and dilution ratio measuring method |
US9080993B2 (en) * | 2008-07-29 | 2015-07-14 | Sharp Kabushiki Kaisha | Microdevice, microchip apparatus and analysis method utilizing the same |
US7947492B2 (en) * | 2008-08-20 | 2011-05-24 | Northeastern Ohio Universities College Of Medicine | Device improving the detection of a ligand |
KR101390717B1 (en) * | 2008-09-02 | 2014-04-30 | 삼성전자주식회사 | Microfluidic device and method of loading sample thereto |
US9289765B2 (en) * | 2008-09-23 | 2016-03-22 | Samsung Electronics Co., Ltd. | Micro-fluidic device and sample testing apparatus using the same |
WO2010042355A1 (en) * | 2008-10-06 | 2010-04-15 | Response Biomedical Corporation | Sample preparation device |
US20100088855A1 (en) * | 2008-10-14 | 2010-04-15 | Magna Mirrors Of America, Inc. | Vehicle door handle assembly |
GB2464721C (en) | 2008-10-23 | 2013-08-14 | Biosurfit Sa | Jet deflection device |
GB2466644B (en) * | 2008-12-30 | 2011-05-11 | Biosurfit Sa | Liquid handling |
US7927904B2 (en) | 2009-01-05 | 2011-04-19 | Dalsa Semiconductor Inc. | Method of making BIOMEMS devices |
KR101578149B1 (en) * | 2009-01-29 | 2015-12-17 | 삼성전자주식회사 | Microfluidic valve unit for controlling fluid flow and method for fabricating the same |
KR20100102781A (en) * | 2009-03-12 | 2010-09-27 | 삼성전자주식회사 | Centrifugal force based microfluidic device, and method for fabricating the same |
US20100282980A1 (en) * | 2009-05-11 | 2010-11-11 | Caridianbct Biotechnologies, Llc | Stable Calibration Means for Apparatus for Photo Reduction of Contaminants in Blood |
US20100297745A1 (en) * | 2009-05-19 | 2010-11-25 | Nanyang Technological University | Flow-through method of functionalizing inner surfaces of a microfluidic device |
JP2012529908A (en) | 2009-06-15 | 2012-11-29 | ネットバイオ・インコーポレーテッド | Improved method for quantification of forensic DNA |
TWI360438B (en) * | 2009-08-25 | 2012-03-21 | Ind Tech Res Inst | Analytical system, analytical method and flow-path |
JP5311406B2 (en) * | 2009-09-10 | 2013-10-09 | 独立行政法人産業技術総合研究所 | Immunosensor |
KR20110043034A (en) * | 2009-10-20 | 2011-04-27 | 삼성전자주식회사 | Microfluidic device and method of testing sample using the same |
US20120282682A1 (en) * | 2009-11-02 | 2012-11-08 | Ffei Limited | Micro-channel structure method and apparatus |
US20110117607A1 (en) * | 2009-11-13 | 2011-05-19 | 3M Innovative Properties Company | Annular compression systems and methods for sample processing devices |
USD638951S1 (en) | 2009-11-13 | 2011-05-31 | 3M Innovative Properties Company | Sample processing disk cover |
US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
USD667561S1 (en) | 2009-11-13 | 2012-09-18 | 3M Innovative Properties Company | Sample processing disk cover |
USD638550S1 (en) | 2009-11-13 | 2011-05-24 | 3M Innovative Properties Company | Sample processing disk cover |
KR101422573B1 (en) | 2009-11-26 | 2014-07-25 | 삼성전자 주식회사 | Centrifugal Micro-fluidic Device and Method to measure biological makers from liquid specimen |
GB2476474B (en) | 2009-12-22 | 2012-03-28 | Biosurfit Sa | Surface plasmon resonance detection system |
US20110292963A1 (en) * | 2010-01-28 | 2011-12-01 | Conductive Compounds, Inc. | Laser position detection system |
JP2011155921A (en) * | 2010-02-02 | 2011-08-18 | Seiko Epson Corp | Biochip, specimen reactor, and method for specimen reaction |
GB201003614D0 (en) * | 2010-03-04 | 2010-04-21 | Airbus Operations Ltd | Water drain tool |
GB2479139A (en) | 2010-03-29 | 2011-10-05 | Biosurfit Sa | A liquid distribution and metering device |
AU2011305254B2 (en) * | 2010-09-26 | 2014-06-05 | Da Yu Enterprises, L.L.C. | Separation of analytes |
KR20120091631A (en) * | 2011-02-09 | 2012-08-20 | 삼성전자주식회사 | Microfluidic device |
KR20120093636A (en) * | 2011-02-15 | 2012-08-23 | 삼성전자주식회사 | Microfluidic device |
PL3270141T3 (en) * | 2011-03-08 | 2021-04-19 | UNIVERSITé LAVAL | Fluidic centripetal device |
WO2012122628A1 (en) * | 2011-03-15 | 2012-09-20 | National Research Council Of Canada | Microfluidic system having monolithic nanoplasmonic structures |
BR112013024496A2 (en) * | 2011-03-24 | 2016-12-27 | Biosurfit Sa | Liquid flow sequence control in microfluidic device |
EP3682970A1 (en) * | 2011-03-24 | 2020-07-22 | Boehringer Ingelheim Microparts GmbH | Device for removing a supernatant of a liquid sample |
BR112013026451B1 (en) | 2011-04-15 | 2021-02-09 | Becton, Dickinson And Company | system and method to perform molecular diagnostic tests on several samples in parallel and simultaneously amplification in real time in plurality of amplification reaction chambers |
JP5740650B2 (en) * | 2011-05-17 | 2015-06-24 | 国立研究開発法人産業技術総合研究所 | Disk type microfluidic chip and measurement system using the same |
WO2012158988A1 (en) * | 2011-05-18 | 2012-11-22 | 3M Innovative Properties Company | Systems and methods for valving on a sample processing device |
USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
WO2012158990A1 (en) * | 2011-05-18 | 2012-11-22 | 3M Innovative Properties Company | Systems and methods for volumetric metering on a sample processing device |
ES2870874T3 (en) | 2011-05-18 | 2021-10-27 | Diasorin S P A | Systems and methods for detecting the presence of a selected volume of material in a sample processing device |
JP6200419B2 (en) | 2011-06-03 | 2017-09-20 | ラディセンス ダイアグノスティクス リミテッド | Microfluidic disc for use in bead-based immunoassays |
GB2491813A (en) * | 2011-06-03 | 2012-12-19 | Univ Dublin City | A microfluidic device with sacrificial valve |
JP2013033687A (en) | 2011-08-03 | 2013-02-14 | Sharp Corp | Storage battery module |
EP2751021A4 (en) | 2011-08-30 | 2015-09-30 | Univ Mcgill | Method and system for pre-programmed self-power microfluidic circuits |
WO2013037284A1 (en) * | 2011-09-15 | 2013-03-21 | The Chinese University Of Hong Kong | Microfluidic platform and method for controlling the same |
JP5465758B2 (en) * | 2011-09-26 | 2014-04-09 | 富士フイルム株式会社 | Thyroxine immunoassay using fluorescent particles |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
WO2013049706A1 (en) | 2011-09-30 | 2013-04-04 | Becton, Dickinson And Company | Unitized reagent strip |
EP2766735B1 (en) * | 2011-10-14 | 2017-02-01 | Université de Liège | Method for measuring beta-lactam antibiotics |
JP5951219B2 (en) * | 2011-10-24 | 2016-07-13 | ローム株式会社 | Microchip with built-in liquid reagent |
WO2013067202A1 (en) | 2011-11-04 | 2013-05-10 | Handylab, Inc. | Polynucleotide sample preparation device |
JP6104269B2 (en) * | 2011-12-01 | 2017-03-29 | バイオサーフィット、 ソシエダッド アノニマ | Photometric measuring device and photometric measuring method |
JP6257521B2 (en) * | 2011-12-08 | 2018-01-10 | バイオサーフィット、 ソシエダッド アノニマ | Determination of sequential dispensing and sedimentation rate indicators |
US8696098B2 (en) * | 2011-12-09 | 2014-04-15 | Xerox Corporation | Printhead having particle circulation with separation |
CN104204812B (en) | 2012-02-03 | 2018-01-05 | 贝克顿·迪金森公司 | The external file that compatibility determines between distributing and test for molecule diagnostic test |
DE102012202775B4 (en) * | 2012-02-23 | 2016-08-25 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | FLUIDIKMODUL, DEVICE AND METHOD FOR PUMPING A LIQUID |
RU2015107730A (en) | 2012-08-08 | 2016-09-27 | Конинклейке Филипс Н.В. | CENTRIFUGAL MICROFLUIDIC DEVICE AND METHODS OF APPLICATION |
HUE064183T2 (en) | 2012-10-08 | 2024-02-28 | Bl Technologies Inc | Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making |
KR20140055528A (en) * | 2012-10-31 | 2014-05-09 | 삼성전자주식회사 | Microfluidic structure, microfluidic system and control method for microfluidic test device |
US10130947B2 (en) * | 2012-12-05 | 2018-11-20 | Radisens Diagnostics Limited | Valving system for use in centrifugal microfluidic platforms |
US10888862B2 (en) | 2012-12-05 | 2021-01-12 | Radisens Diagnostics Limited | Acceleration-primed valving system for centrifugal microfluidics |
US20150316542A1 (en) | 2012-12-05 | 2015-11-05 | Radisens Diagnostics Limited | Reference and Normalisation Method for Use With Bead-Based Immunoassays in a Microfluidic Disc |
WO2014104830A1 (en) * | 2012-12-27 | 2014-07-03 | 성균관대학교산학협력단 | Nucleic acid amplification disc device using heat-sensitive polymer composite, and analysis method using same |
WO2014148193A1 (en) * | 2013-03-21 | 2014-09-25 | 日本電気株式会社 | Electrophoresis device, and electrophoresis method |
DE102013206622B4 (en) * | 2013-04-13 | 2017-10-19 | Pr Germany Gmbh | Closure element in the form of a window or a door |
JP6244589B2 (en) * | 2013-05-21 | 2017-12-13 | 国立大学法人名古屋大学 | Micro-channel chip for separating fine particles, advection integrated unit, system for separating fine particles, and method for separating fine particles |
US9308508B2 (en) | 2013-07-22 | 2016-04-12 | Kianoosh Peyvan | Sequential delivery device and method |
KR20150027939A (en) * | 2013-09-04 | 2015-03-13 | 삼성전자주식회사 | Microfluidic apparatus |
ITMI20131541A1 (en) * | 2013-09-19 | 2015-03-20 | Eugenio Iannone | DIAGNOSIS DEVICE, PARTICULARLY OF THE LAB-ON-CHIP TYPE. |
US10076751B2 (en) * | 2013-12-30 | 2018-09-18 | General Electric Company | Systems and methods for reagent storage |
GB201401422D0 (en) * | 2014-01-28 | 2014-03-12 | Secr Defence | Method and device for heating a chemical reaction |
AU2015221851B2 (en) * | 2014-02-25 | 2019-05-09 | C.Y. O'connor Erade Village Foundation Inc. | Methods and systems for measuring melting temperatures |
EP3141592B1 (en) * | 2014-05-08 | 2020-03-11 | Osaka University | Heat convection-generating chip and liquid-weighing instrument |
US9347958B2 (en) * | 2014-06-27 | 2016-05-24 | Hemocue Ab | Device and method for determination of an analyte in blood |
WO2016002729A1 (en) | 2014-06-30 | 2016-01-07 | パナソニックヘルスケアホールディングス株式会社 | Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system |
EP3163306A4 (en) | 2014-06-30 | 2018-01-24 | Panasonic Healthcare Holdings Co., Ltd. | Substrate for sample analysis, and sample analysis apparatus |
JP6588909B2 (en) * | 2014-06-30 | 2019-10-09 | Phcホールディングス株式会社 | Sample analysis substrate, sample analysis system, and method for removing liquid from liquid containing magnetic particles |
US10309976B2 (en) | 2014-06-30 | 2019-06-04 | Phc Holdings Corporation | Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system |
CN105717313A (en) * | 2014-12-04 | 2016-06-29 | 广明光电股份有限公司 | Biological disc detection drive device and method |
JP6660305B2 (en) | 2014-12-12 | 2020-03-11 | Phcホールディングス株式会社 | Sample analysis substrate, sample analyzer, sample analysis system, and program for sample analysis system |
US9736888B2 (en) * | 2015-03-12 | 2017-08-15 | The Boeing Company | Composite panel with integrated heater and associated methods for manufacturing |
US10356847B2 (en) | 2015-03-12 | 2019-07-16 | The Boeing Company | Composite panel with integrated heater system and associated methods for manufacturing |
EP3311160B1 (en) * | 2015-06-20 | 2020-12-23 | Capitainer AB | A plasma separating microfluidic device |
DE212016000165U1 (en) * | 2015-08-07 | 2018-04-16 | Poc Medical Systems Inc. | microfluidic devices |
US10501715B1 (en) * | 2015-09-11 | 2019-12-10 | Mark H. Widick | System for the formation of fibrin foam |
USD799715S1 (en) | 2015-10-23 | 2017-10-10 | Gene POC, Inc. | Fluidic centripetal device |
US11331665B2 (en) * | 2016-01-18 | 2022-05-17 | The Board Of Trustees Of The Leland Stanford Junior University | Paperfuge: An integrated paper-based centrifugation and microfluidics platform for low-cost diagnostics |
JP6868639B2 (en) | 2016-03-18 | 2021-05-12 | クイデル カーディオバスキュラー インコーポレイテッド | Microfluidic devices, systems, and methods |
US10368396B2 (en) | 2016-04-01 | 2019-07-30 | The Boeing Company | Heat pipe with printed heater and associated methods for manufacturing |
CN107398307B (en) | 2016-05-18 | 2023-07-25 | 博奥生物集团有限公司 | Integrated micro-fluidic chip |
CN106513063B (en) * | 2016-06-06 | 2018-09-07 | 苏州汶颢芯片科技有限公司 | The centrifugal chip and its mixed method of consecutive reaction can be achieved |
JP7387430B2 (en) * | 2016-06-27 | 2023-11-28 | ゾエティス サービシズ リミテッド ライアビリティ カンパニー | Devices with modified conduits |
JP6635897B2 (en) * | 2016-08-30 | 2020-01-29 | シスメックス株式会社 | Sample analysis cartridge, method for producing the same, and use thereof |
EP3519005B1 (en) * | 2016-10-03 | 2023-09-13 | Terumo BCT, Inc. | Centrifugal fluid separation device |
US10639635B2 (en) | 2016-10-07 | 2020-05-05 | Biosurfit, SA | Device and method for handling liquid |
US10591078B2 (en) | 2016-12-15 | 2020-03-17 | The Boeing Company | Fluid flow control device |
WO2018165440A1 (en) * | 2017-03-08 | 2018-09-13 | Northwestern University | Devices, systems, and methods for specimen preparation and analysis using capillary and centrifugal forces |
DE102017204002B4 (en) | 2017-03-10 | 2019-05-23 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | CENTRIFUGO-PNEUMATIC SWITCHING OF LIQUID |
US11318466B2 (en) | 2017-07-19 | 2022-05-03 | Hewlett-Packard Development Company, L.P. | Microfluidic fluid flow in a target fluid |
JP6876328B2 (en) * | 2017-08-28 | 2021-05-26 | 国立大学法人大阪大学 | Container and its manufacturing method and detection method of test substance |
KR102137306B1 (en) | 2017-11-20 | 2020-07-23 | 주식회사 엘지화학 | A device and method for qualitative and quantitative analysis of heavy metals using a rotary disc system |
JP6950955B2 (en) * | 2017-12-28 | 2021-10-13 | 国立研究開発法人産業技術総合研究所 | Assay device |
US10935149B2 (en) | 2018-03-15 | 2021-03-02 | University Of Washington | Temperature-actuated valve, fluidic device, and related methods of use |
JP6846388B2 (en) * | 2018-06-26 | 2021-03-24 | シスメックス株式会社 | Measurement cartridge and liquid feeding method |
KR20200009859A (en) * | 2018-07-20 | 2020-01-30 | 재단법인대구경북과학기술원 | An apparatus to control centrifugal valves |
KR102401909B1 (en) * | 2018-08-30 | 2022-05-24 | 주식회사 엘지화학 | A high-speed screening analysis system for reaction optimization |
GB201820617D0 (en) * | 2018-12-18 | 2019-01-30 | Greindx As | System for capturing cells |
WO2020204232A1 (en) * | 2019-04-04 | 2020-10-08 | 바이오뱅크 주식회사 | Multi-system for simultaneously performing biochemical test and blood test, and multi-disc used therefor |
CN110762238B (en) * | 2019-11-19 | 2021-05-04 | 华北水利水电大学 | Automatic fluid flow rate control device |
CA3198897A1 (en) * | 2019-12-13 | 2021-03-19 | Autonomous Medical Devices Inc. | Apparatus and method for point-of-care, rapid, field-deployable diagnostic testing of covid-19, viruses, antibodies and markers |
GB202001399D0 (en) * | 2020-01-31 | 2020-03-18 | Odx Innovations Ltd | Centrifugally motivated fluidic systems, devices and methods |
CN111207242B (en) * | 2020-04-18 | 2020-09-01 | 博奥生物集团有限公司 | Fluid actuated control valve and method of use |
EP3978125A1 (en) * | 2020-09-30 | 2022-04-06 | iCare Diagnostics International Co. Ltd. | Nucleic acid detection kit and nucleic acid detection device |
KR20220135997A (en) * | 2021-03-31 | 2022-10-07 | 주식회사 씨티셀즈 | Apparatus to control cell separation |
DE102021208891B3 (en) | 2021-08-13 | 2022-10-13 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Fluid vacuum switching |
GB202118919D0 (en) * | 2021-12-23 | 2022-02-09 | Osler Diagnostics Ltd | Liquid handling device |
US11964277B2 (en) * | 2022-03-10 | 2024-04-23 | Hewlett-Packard Development Company, L.P. | Metered volume microfluidic devices |
Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1292407A (en) * | 1961-03-24 | 1962-05-04 | Rotary electric distributor | |
US3713062A (en) * | 1970-12-29 | 1973-01-23 | Texas Instruments Inc | Snap disc thermal sequencer |
GB1307628A (en) * | 1970-08-21 | 1973-02-21 | Ver Volkseigener Betriebe Elek | Slip ring assembly for electrical machines |
US3952116A (en) * | 1974-09-17 | 1976-04-20 | Texas Instruments Incorporated | Process for forming electrical resistance heaters |
US4030834A (en) * | 1976-04-08 | 1977-06-21 | The United States Of America As Represented By The United States Energy Research And Development Administration | Dynamic multistation photometer |
US4258740A (en) * | 1977-05-16 | 1981-03-31 | Packard Instrument Company, Inc. | Fluid flow control device |
US4722853A (en) * | 1985-08-12 | 1988-02-02 | Raychem Corporation | Method of printing a polymer thick film ink |
US4872821A (en) * | 1987-03-23 | 1989-10-10 | Gold Medal Products Co. | Cotton candy machine |
EP0408207A2 (en) * | 1989-07-13 | 1991-01-16 | Illinois Tool Works Inc. | Positive temperature coefficient heater |
US5160702A (en) * | 1989-01-17 | 1992-11-03 | Molecular Devices Corporation | Analyzer with improved rotor structure |
US5171533A (en) * | 1989-07-31 | 1992-12-15 | Fine Richard A | Biological assay cassette and method for making same |
WO1994026414A1 (en) * | 1993-05-17 | 1994-11-24 | Syntex (U.S.A.) Inc. | Reaction container for specific binding assays and method for its use |
WO1996007919A1 (en) * | 1994-09-02 | 1996-03-14 | Biometric Imaging, Inc. | A disposable cartridge and method for an assay of a biological sample |
WO1997008556A1 (en) * | 1995-08-31 | 1997-03-06 | First Medical, Inc. | Analytical rotor and method for detecting analytes in liquid samples |
WO1997021090A1 (en) * | 1995-12-05 | 1997-06-12 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
WO1998007019A1 (en) * | 1996-08-12 | 1998-02-19 | Gamera Bioscience Corporation | Capillary microvalve |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3528449A (en) * | 1968-02-27 | 1970-09-15 | Trw Inc | Fluid flow control apparatus |
US3679367A (en) | 1970-09-14 | 1972-07-25 | Technicon Instr | Apparatus for determining the pack volume of particulates in liquid mixtures |
US3916152A (en) * | 1972-05-31 | 1975-10-28 | Union Carbide Corp | Temperature control system for a centrifugal-type chemistry analyzer |
FR2400700A1 (en) | 1977-08-18 | 1979-03-16 | Guigan Jean | CONDITIONING DEVICE FOR A LIQUID SAMPLE FOR ANALYSIS |
FR2409514A1 (en) | 1977-11-17 | 1979-06-15 | Bretaudiere Jean Pierre | DEVELOPMENT OF CENTRIFUGATION ANALYSIS EQUIPMENT |
US4381291A (en) | 1979-02-23 | 1983-04-26 | Ab Fortia | Measurement of free ligands |
DE3044385A1 (en) | 1980-11-25 | 1982-06-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD FOR CARRYING OUT ANALYTICAL PROVISIONS AND ROTOR INSERT ELEMENT SUITABLE FOR THIS |
US4729862A (en) | 1981-04-24 | 1988-03-08 | Allied-Signal Inc. | Nylon composition for use in rotational molding |
US5496520A (en) | 1982-01-08 | 1996-03-05 | Kelton; Arden A. | Rotary fluid manipulator |
DE3314961A1 (en) | 1983-04-25 | 1984-10-25 | Boehringer Mannheim Gmbh, 6800 Mannheim | ANALYZER FOR PHOTOMETRICALLY DETERMINING A PARAMETER OF A LIQUID |
GB8317124D0 (en) | 1983-06-23 | 1983-07-27 | Ekins R P | Free ligand assay |
US4612959A (en) * | 1985-05-07 | 1986-09-23 | Mobil Oil Corporation | Valveless shut-off and transfer device |
WO1988001058A1 (en) | 1986-08-06 | 1988-02-11 | Roger Philip Ekins | Determination of analyte concentration using two labelling markers |
US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US4940527A (en) | 1987-06-01 | 1990-07-10 | Abbott Laboratories | Two-part test cartridge for centrifuge |
US5173262A (en) | 1987-07-17 | 1992-12-22 | Martin Marietta Energy Systems, Inc. | Rotor assembly and method for automatically processing liquids |
US5242803A (en) | 1987-07-17 | 1993-09-07 | Martin Marietta Energy Systems, Inc. | Rotor assembly and assay method |
EP0305210B1 (en) | 1987-08-27 | 1993-12-08 | Biotrack, Inc. | Apparatus and method for dilution and mixing of liquid samples |
US4999304A (en) | 1987-12-28 | 1991-03-12 | Miles Inc. | Dynamic braking centrifuge |
US5252294A (en) | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
KR920700403A (en) | 1989-03-07 | 1992-02-19 | 혼고오 므쯔미 | Analysis device for liquid samples and analysis method for liquid samples using this analysis device |
US5006749A (en) | 1989-10-03 | 1991-04-09 | Regents Of The University Of California | Method and apparatus for using ultrasonic energy for moving microminiature elements |
US5186844A (en) | 1991-04-01 | 1993-02-16 | Abaxis, Inc. | Apparatus and method for continuous centrifugal blood cell separation |
US5122284A (en) | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
US5061381A (en) | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
US5242606A (en) | 1990-06-04 | 1993-09-07 | Abaxis, Incorporated | Sample metering port for analytical rotor having overflow chamber |
US5173193A (en) | 1991-04-01 | 1992-12-22 | Schembri Carol T | Centrifugal rotor having flow partition |
DE69230951T2 (en) * | 1991-06-11 | 2001-03-01 | Univ Cambridge Tech | Centrifuges, in particular for geotechnical test methods |
US5413732A (en) | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
US5304348A (en) | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
US5195967A (en) * | 1992-02-18 | 1993-03-23 | Nakao Naomi L | Anticlotting device and method for use with IV catheters |
WO1993019827A1 (en) | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
US5275016A (en) | 1992-04-24 | 1994-01-04 | Abaxis, Inc. | Cryogenic apparatus |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
WO1993022058A1 (en) | 1992-05-01 | 1993-11-11 | Trustees Of The University Of Pennsylvania | Polynucleotide amplification analysis using a microfabricated device |
US5259829A (en) * | 1993-01-11 | 1993-11-09 | Vanegmond Cornelis F H | Centrifugal separating apparatus |
JPH06265447A (en) | 1993-03-16 | 1994-09-22 | Hitachi Ltd | Trace quantity reactor and trace element measuring instrument therewith |
US5478750A (en) | 1993-03-31 | 1995-12-26 | Abaxis, Inc. | Methods for photometric analysis |
US5432009A (en) | 1993-06-17 | 1995-07-11 | Sekisui Kagaku Kogyo Kabushiki Kaisha | Film for first-aid sticking plaster |
US5368704A (en) | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
US5591643A (en) | 1993-09-01 | 1997-01-07 | Abaxis, Inc. | Simplified inlet channels |
US5409665A (en) | 1993-09-01 | 1995-04-25 | Abaxis, Inc. | Simultaneous cuvette filling with means to isolate cuvettes |
US5431303A (en) * | 1993-09-30 | 1995-07-11 | Miskell; David L. | Two-part aerosol dispenser employing fusible plug |
US5403415A (en) | 1993-11-17 | 1995-04-04 | Abaxis, Inc. | Method and device for ultrasonic welding |
JP3365067B2 (en) | 1994-02-10 | 2003-01-08 | ソニー株式会社 | Plasma apparatus and plasma processing method using the same |
US5413009A (en) | 1994-03-16 | 1995-05-09 | Fragnito; Frank | Variable speed transmission assembly |
DE4410224C2 (en) | 1994-03-24 | 1996-02-29 | Meinhard Prof Dr Knoll | Miniaturized flow analysis system |
US5590052A (en) | 1994-04-14 | 1996-12-31 | Abaxis, Inc. | Error checking in blood analyzer |
EP0764266A4 (en) | 1994-06-06 | 1998-08-05 | Abay Sa | Modified siphons for improved metering precision |
US5639428A (en) | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
US5593378A (en) * | 1995-03-07 | 1997-01-14 | Dyck; Howard F. | Centrifugal separator for flowable mixtures and having magnets and housing scrapers |
US5622819A (en) * | 1995-03-28 | 1997-04-22 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
JP3469585B2 (en) * | 1997-05-23 | 2003-11-25 | ガメラ バイオサイエンス コーポレイション | Apparatus and method for using centripetal acceleration to drive flow motion in microfluidics systems |
WO2000069560A1 (en) * | 1999-05-14 | 2000-11-23 | Gamera Bioscience Corporation | A centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids |
DE19944617C2 (en) * | 1999-09-17 | 2002-01-10 | Fresenius Ag | Centrifuge with a magnetic gear |
-
1998
- 1998-05-22 JP JP55068998A patent/JP3469585B2/en not_active Expired - Fee Related
- 1998-05-22 WO PCT/US1998/010520 patent/WO1998053311A2/en active Application Filing
- 1998-05-22 EP EP98923688A patent/EP0983504A2/en not_active Withdrawn
- 1998-05-22 AU AU75919/98A patent/AU7591998A/en not_active Abandoned
- 1998-05-22 US US09/083,678 patent/US6063589A/en not_active Expired - Fee Related
-
2000
- 2000-03-15 US US09/526,496 patent/US6302134B1/en not_active Expired - Fee Related
- 2000-12-21 US US09/745,922 patent/US6399361B2/en not_active Expired - Fee Related
-
2001
- 2001-10-16 US US09/981,007 patent/US6548788B2/en not_active Expired - Fee Related
-
2002
- 2002-04-09 JP JP2002107192A patent/JP3725834B2/en not_active Expired - Fee Related
- 2002-12-02 JP JP2002349755A patent/JP3537813B2/en not_active Expired - Fee Related
-
2003
- 2003-04-15 US US10/414,536 patent/US6719682B2/en not_active Expired - Fee Related
-
2004
- 2004-04-13 US US10/823,401 patent/US20040191125A1/en not_active Abandoned
-
2005
- 2005-08-12 JP JP2005235045A patent/JP2005326432A/en active Pending
Patent Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1292407A (en) * | 1961-03-24 | 1962-05-04 | Rotary electric distributor | |
GB1307628A (en) * | 1970-08-21 | 1973-02-21 | Ver Volkseigener Betriebe Elek | Slip ring assembly for electrical machines |
US3713062A (en) * | 1970-12-29 | 1973-01-23 | Texas Instruments Inc | Snap disc thermal sequencer |
US3952116A (en) * | 1974-09-17 | 1976-04-20 | Texas Instruments Incorporated | Process for forming electrical resistance heaters |
US4030834A (en) * | 1976-04-08 | 1977-06-21 | The United States Of America As Represented By The United States Energy Research And Development Administration | Dynamic multistation photometer |
US4258740A (en) * | 1977-05-16 | 1981-03-31 | Packard Instrument Company, Inc. | Fluid flow control device |
US4722853A (en) * | 1985-08-12 | 1988-02-02 | Raychem Corporation | Method of printing a polymer thick film ink |
US4872821A (en) * | 1987-03-23 | 1989-10-10 | Gold Medal Products Co. | Cotton candy machine |
US5160702A (en) * | 1989-01-17 | 1992-11-03 | Molecular Devices Corporation | Analyzer with improved rotor structure |
EP0408207A2 (en) * | 1989-07-13 | 1991-01-16 | Illinois Tool Works Inc. | Positive temperature coefficient heater |
US5171533A (en) * | 1989-07-31 | 1992-12-15 | Fine Richard A | Biological assay cassette and method for making same |
WO1994026414A1 (en) * | 1993-05-17 | 1994-11-24 | Syntex (U.S.A.) Inc. | Reaction container for specific binding assays and method for its use |
WO1996007919A1 (en) * | 1994-09-02 | 1996-03-14 | Biometric Imaging, Inc. | A disposable cartridge and method for an assay of a biological sample |
WO1997008556A1 (en) * | 1995-08-31 | 1997-03-06 | First Medical, Inc. | Analytical rotor and method for detecting analytes in liquid samples |
WO1997021090A1 (en) * | 1995-12-05 | 1997-06-12 | Gamera Bioscience | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
WO1998007019A1 (en) * | 1996-08-12 | 1998-02-19 | Gamera Bioscience Corporation | Capillary microvalve |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9396752B2 (en) | 2005-08-05 | 2016-07-19 | Searete Llc | Memory device activation and deactivation |
Also Published As
Publication number | Publication date |
---|---|
JP2005326432A (en) | 2005-11-24 |
US20030195106A1 (en) | 2003-10-16 |
US20010001060A1 (en) | 2001-05-10 |
JP2003028883A (en) | 2003-01-29 |
WO1998053311A2 (en) | 1998-11-26 |
US6399361B2 (en) | 2002-06-04 |
JP3469585B2 (en) | 2003-11-25 |
US6719682B2 (en) | 2004-04-13 |
AU7591998A (en) | 1998-12-11 |
JP3725834B2 (en) | 2005-12-14 |
US20020027133A1 (en) | 2002-03-07 |
US6063589A (en) | 2000-05-16 |
JP3537813B2 (en) | 2004-06-14 |
US6302134B1 (en) | 2001-10-16 |
WO1998053311A9 (en) | 1999-04-22 |
JP2003270252A (en) | 2003-09-25 |
EP0983504A2 (en) | 2000-03-08 |
JP2000514928A (en) | 2000-11-07 |
US6548788B2 (en) | 2003-04-15 |
US20040191125A1 (en) | 2004-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1998053311A3 (en) | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system | |
WO2000079285A3 (en) | Devices and methods for the performance of miniaturized homogeneous assays | |
WO2004058406A3 (en) | Microfluidics devices and methods for diluting samples and reagents | |
MX9804463A (en) | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics | |
WO2001087485A3 (en) | Microfluidics devices and methods for high throughput screening | |
ATE395136T1 (en) | DEVICES FOR PERFORMING MINIATURIZED IN VITRO AMPLIFICATION ASSAY | |
WO2001087487A3 (en) | Bidirectional flow centrifugal microfluidic devices | |
Geschke et al. | Microsystem Engineering of Lab-on-a-chip Devices | |
US20010055812A1 (en) | Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics | |
Lee et al. | Integrated microfluidic systems for cell lysis, mixing/pumping and DNA amplification | |
Bousse et al. | Electrokinetically controlled microfluidic analysis systems | |
Thio et al. | Theoretical development and critical analysis of burst frequency equations for passive valves on centrifugal microfluidic platforms | |
US7332326B1 (en) | Centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids | |
CN110045102B (en) | Reagent sequential loading device, centrifugal microfluidic device and analysis system | |
Aeinehvand et al. | Reversible thermo-pneumatic valves on centrifugal microfluidic platforms | |
WO2000069560A1 (en) | A centripetally-motivated microfluidics system for performing in vitro hybridization and amplification of nucleic acids | |
WO2001034302A3 (en) | Biochannel assay for hybridization with biomaterial | |
WO2008024319A8 (en) | Microfluidic devices for nucleic acid assembly | |
WO2003048736A3 (en) | Microfluidic device and surface decoration process for solid phase affinity binding assays | |
WO2006124458A3 (en) | Method and device for conducting biochemical or chemical reactions at multiple temperatures | |
WO2005010147A3 (en) | Device and method for contacting pocoliter volumes of fluids | |
CN101613660B (en) | Methods and apparatus for pathogen detection and analysis | |
WO2003054513A3 (en) | Centrifugal array processing device | |
EP1577010A3 (en) | Microsystem platform and its use | |
WO2003083491A3 (en) | Method and apparatus for controlling fluid movement in a microfluidic system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
AK | Designated states |
Kind code of ref document: C2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: C2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
COP | Corrected version of pamphlet |
Free format text: PAGES 1-3, 6-8, 10-15, 17, 18, 21, 22, 24-29, 31-37, 39, 43-46, 48-55, 57, 59-61, 63, 65-73, 75-78 AND 80-85, DESCRIPTION, REPLACED BY NEW PAGES 1-3, 6-8, 10-15, 17, 18, 21, 22, 24-29, 31-37, 39, 43-46, 48-55, 57, 59-61, 63, 65-73, 75-78 AND 80-85; PAGES 113-115, CLAIMS, REPLACED BY NEW PAGES 113-115; PAGES 1/64-64/64, DRAWINGS, REPLACED BY NEW PAGES 1/111-111/111; AFTER RECTIFICATION OF OBVIOUS ERRORS AS AUTHORIZED BY THE INTERNATIONAL SEARCHING AUTHORITY |
|
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 1998 550689 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1998923688 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1998923688 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
NENP | Non-entry into the national phase |
Ref country code: CA |