WO1997025997A1 - Tea, kit and method for treating hemorrhoids - Google Patents
Tea, kit and method for treating hemorrhoids Download PDFInfo
- Publication number
- WO1997025997A1 WO1997025997A1 PCT/US1997/000428 US9700428W WO9725997A1 WO 1997025997 A1 WO1997025997 A1 WO 1997025997A1 US 9700428 W US9700428 W US 9700428W WO 9725997 A1 WO9725997 A1 WO 9725997A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- equisetum
- forma
- composition
- equisemm
- herb
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Definitions
- This invention relates to a treatment for hemorrhoids and symptoms thereof; and, more particularly, it relates to a composition of matter, tea, kit and treatment for the condition of hemorrhoids.
- the anorectal region is generally comprised of the anus, rectum, and lower colon.
- hemorrhoids or piles are a common ailment of the anorectal region, and may be internally or externally located in the anorectal area. Notwithstanding their location, veins in the anorectal area become inflamed and frequently result in itching.
- the causes of hemorrhoids include predisposing causes such as erect posture, heredity, occupation and diet, constipation, diarrhea, pregnancy, anal infection, pelvic tumors, rectal carcinoma, cardiac failure, portal hypertension, vomiting and physical exertion.
- 1,890,596 to Zographos discloses an ointment comprising extracts of powdered calomel and green tansy weed
- U.S. Patent No. 3,935,310 to Homan discloses a composition comprising extracts of Celastrus scandens
- U.S. Patent No. 4,761,285 to Vasiliou et al. discloses a composition comprising extracts of Leptandra root, chick peas and grape seeds
- U.S. Patent No. 3,464,972 to Roche r discloses a composition comprising extracts of Ficaria ranunculus
- U.S. Patent No. 5,002,767 to Masse discloses a composition comprising extracts of the Resedaceae family. Yet none of these compositions involve the use of the combination of the herbs described in the present invention.
- hemorrhoids is complicated by the fact that during defecation, the fecal mass stretches, tears and irritates the already inflamed and swollen hemorrhoidal tissue. Further, as a result of additional muscle strain during defecation resulting from the physical movement of the fecal mass through the already swollen and inflamed tissue, he ⁇ iiation of the anal walls frequently results. Moreover, the excretory tract is the site of numerous organisms that are infectious and that enjoy infiltrating the anal cavity herniations. This infiltration further damages already damaged tissue and aggravates the healing process. If left untreated hemorrhoids often worsen and require surgery to remove the diseased hemorrhoidal tissue.
- Treatments of hemorrhoids have tended to focus on topical applications of creams and lotions and suppositories having medicaments therein that have sought to relieve itching (Pruritis ani) and/or inflammation.
- the efficacy of the prior art treatments in relieving or curing a variety of symptoms is uncertain.
- Exemplary such creams or lotions are described in: U.S. Patent No. 4,169,143 to Haimowitz which discloses a treatment of hemorrhoids with compositions comprising Vitamin E; U.S. Patent No. 3,062.716 to Montandraud which discloses a treatment of hemorrhoids with compositions comprising heparin; U.S. Patent No.
- 4,945,084 to Packman discloses a treatment of hemorrhoids with disaccharide polysulfate-aluminum compounds
- U.S. Patent No. 4,118,480 to Williams discloses a treatment of hemorrhoids with a mixture of compounds
- U.S. Patent No. 4,202,825 to Taya discloses a treatment of hemorrhoids with a derivative of quercetin
- U.S. Patent No. 4,265,887 to Breskman discloses a treatment of hemorrhoids with a mixture of vitamins
- 4,626,433 to Gold discloses a treatment of hemorrhoids with a salve comprising aluminum potassium sulfate, linseed oil, methanol, camphor and pure petroleum jelly;
- U.S. Patent No. 4,985,257 to Verde discloses a treatment of hemorrhoids with a composition comprising cream of tartar;
- U.S. Patent No. 5,196,405 to Oakman discloses a treatment of hemorrhoids with a composition comprising disaccharide poly ⁇ sulfate-aluminum compounds;
- U.S. Patent No. 5.234,914 to Gallina discloses a treatment of hemorrhoids with a composition comprising hyaluronic acid; and.
- An anti-hemorrhoidal composition, tea, and kit containing tea bags including, in combination, a first herb of the genus Equisetaceae and a second herb of the family Julianiaceae, genus amphipterygium adstringens is provided herein.
- the herb from the genus is provided herein.
- Equisetaceae is selected from the group consisting of Horsetail. Equisetum arvense,
- Equisetum palustre Equisetum pratense , Equisetum scirpoides, Equisetum sylvaticum, Equisetum Telemateia, Equisetum variegatum, Equisetum debile, Equisetum elongatum, Equisetum giganteum, and Equisetum maximum.
- the herb from the genus Equisetum arvense is selected from the group consisting of Equisetum arvense var. boreale, Equisetum arvense forma alpestre, Equisetum arvense forma campestre,
- the herb, Equisetum hyemale is selected from the group consisting of Equisetum hyemale var. affine, Equisetum hyemale var. intermedium, Equisetum hyemale var. rubustum, Equisetum hyemale io ⁇ mzpolystachyum, Equisetum hyemale forma proliferum, and Equisetum hyemale forma pumilum
- the herb, Equisetum palustre is selected from the group consisting ot Equisetum palustre forma arcuatum
- Equisetum Telemateia is selected from the group consisting of Equisetum Telemateia var. pauciramosum, and Equisetum Telemateia forma mul ⁇ rammosum.
- the second herb of the family Julianiaceae, genus amphipterygium adstringens is selected from the group consisting of cuachalalate .
- the method of manufacturing an anti-hemorrhoidal composition includes the steps of admixing an effective amount of a first herb of the genus Equisetaceae and an effective amount of a second herb of the family Julianiaceae, genus amphipterygium
- adstringens with a solvent to obtain a herbal mixture.
- the herbal mixture is heated for
- the solvent is
- the method includes the step of steeping the prepared herbal mixture to obtain a steeped herbal mixture and sifting the steeped herbal mixture to obtain a substantially purified herbal tea.
- the antihemorrhoidal composition is
- Packaging includes a tea bag, a capsule, a tablet, a concentrated liquid. and a powdered mixture.
- the first herb and the second herb are separately pulverized in a blender and then mixed in a volume ratio of 1 to 1. Similarly, such a pulverization will generally result in a weight ratio of first herb to second herb of one
- the first herb is half as heavy as the second herb.
- the method of treating hemorrhoids provided herein includes the step of periodically ingesting a therapeutically effective amount of the composition described above. It is a further object of the present invention to solve the problems articulated in
- FIG. 1 is a perspective view of the kit of the present invention. DETAILED DESCRIPTION OF THE INVENTION
- the invention is based upon the discovery that ingestion of a processed composition of matter of a first herb of the genus Equisetaceae and a second herb of the Generie Juliania, family Julianiaceae, genus amphipterygium adstringens (also known as "Cuachalalate") as active ingredients relieves hemorrhoidal symptoms and reduces the swelling of hemorrhoids. Periodic ingestion of a therapeutically effective amount of this composition relieves hemorrhoidal symptoms within a short period of time.
- the herb of the genus Equisetaceae is selected from the group consisting of Horsetail (also known as “Canutillo"), Equisetum arvense (also known as “Corn Horsetail” and “Field Horsetail”), Equisetum hyemale (also known as “Common Scouring Rush”), Equisetum fluvia ⁇ le, Equisetum kansanum, Equisetum litorale, Equisetum palustre, Equisetum pratense, Equisetum scirpoides (also known as “Dwarf Scouring Rush”), Equisetum sylva ⁇ cum (also known as “Wood Horsetail”), Equisetum Telemateia, Equisetum variegatum (also known as "Variegated Rush”), Equisenim debile, Equisetum elongatum, Equisetum giganteum, and Equisetum maximum.
- Horsetail also known as “Canutillo”
- Equisetum arvense also known as “Corn Horsetail” and “Field
- Equisetum arvense (also known as "Great River Horsetail” in one variant) is selected from the group consisting of Equisetum arvense var. boreale, Equisetum arvense forma alpestre, Equisetum arvense forma campestre, Equisetum arvense forma diffusum , Equisetum arvense io ⁇ m&pseudo-alpestre, Equisetum arvense iorxmpseudo- ⁇ lvaticum, Equisetum arvense forma pseudo-varium , Equisetum arvense forma ramulosum, and Equisetum arvense forma varium.
- Equisetum hyemale is selected from the group consisting of Equisetum hyemale var. affine (also known as "Equisetum Prealrum"), Equisetum hyemale var. in t ermedium, Equisetum hyemale var. rubustum, Equisetum hyemale forma polystachyum, Equisetum hyemale forma proliferum , and Equisetum hyemale forma pumilum .
- Equisetum palustre is selected from the group consisting oi Equisetum palustre forma arcuatum, Equisetum palustre forma filiforme, Equisetum palustre forma fluitans, Equisetum palustre forma nigridens, Equisetum palustre forma polystachion, Equisetum palustre forma ramulosum, Equisetum palustre forma ver ⁇ cilatum, and Equisetum palustre forma simplex.
- Equisetum Telemateia is selected from the group consisting of Equisetum Telemateia var . pauciramosum , and Equisetum Telemateia forma multirammosum .
- Equisetum Variegatum is selected from the group consisting of Equisenim Variegatum var. jesupi, and Equisetum Variegatum var. nelsoni.
- the form in which the composition is supplied to the consumer is not critical.
- composition can be supplied as a homogeneously blended powder of the desired proportion of the requisite herbs. It is further possible that the homogeneously blended powder could be combined with binding agents and formed into water soluble pills and tablets. These pills and tablets can be compressed and shaped.
- a therapeutically effective amount of the composition is ingested when symptoms of hemorrhoidal suffering are experienced.
- a therapeutically effective quantity is one cup of tea ingested three times a day for a period of one week. One cup daily is then further ingested for approximately another week. Larger quantities of tea are ingested for longer periods of time in cases where the hemorrhoids are severe.
- the dosage may be adjusted by the user to accommodate differences in body weight and severity of the symptoms. Treatment is continued until relief of hemorrhoidal symptoms and reduction of hemorrhoidal swelling has been achieved.
- the present invention further contemplates the addition of unobjectionable adjuvants to the herbal composition such as natural and artificial sweeteners, inert teas, natural flavors, artificial flavors, and coloring agents.
- unobjectionable adjuvants such as natural and artificial sweeteners, inert teas, natural flavors, artificial flavors, and coloring agents.
- Skilled practitioners recognize that addition of the adjuvants affect the weight and volume of the dosage of the herbs at issue. Hence, adjustment of the dosage to account for the presence of the adjuvant is within the skill of the suppliers of the adjuvant products.
- FIG. 1 illustrates a perspective view of a kit of the present invention.
- the kit comprises a container 100 in which a plurality of tea bags 200.
- Tea bags 200 consist of a permeable membrane or filter commonly made of paper as is known in the an.
- a standardized dosage includes twenty eight (28) tea bags. It is understood that any number of tea bags 200 are used in the kit sufficient to provide a therapeutic effect for a subject.
- a basic prescription kit includes sufficient tea bags to make 3 cups (3 bags) per day for 7 days (21 units) and sufficient tea bags to make 1 cup (1 bag) per day for 7 days (7 units) for a minimum total of about 28 units. It is understood that the number of tea bags can be in the range of 1 bag to over 200 bags depending on the needs of the subject.
- An anti-hemorrhoidal tea was made from the mixture of two herbs: a first herb of the genus Equisetaceae and a second herb of the Generie Juliania, family Julianiaceae, genus amphipterygium adstringens.
- a first herb of the genus Equisetaceae and a second herb of the Generie Juliania, family Julianiaceae, genus amphipterygium adstringens.
- about one level tablespoon of crushed cuachalalate herb and " one heaping tablespoon of Horsetail herb were added to three cups of cold water in a tea kettle to create a mixture. The mixture was brought to a boil for one minute and allowed to steep for five minutes to form a tea. The tea was then poured into a cup through a sifter, and ingested by a user while still warm.
- One cup of tea was ingested three times a day for a period of one week.
- One cup daily was then fu ⁇ her ing
- the grounds of the above mixture were also used for a second preparation.
- the remaining grounds from the preparations discussed above were added to three cups of water.
- the mixture was allowed to soak overnight.
- the next morning the mixture was brought to a boil and then ingested as discussed above.
- a base dosage of the tea was a dosage taken over a period of time of about 14 days in one variant, again depending on the severity of the condition.
- Another example of the anti-hemorrhoidal tea was made from the mixture of two herbs: a first herb of the genus Equisetaceae and a second herb of the Generie Juliania, family Julianiaceae , genus amphipterygium adstringens.
- a first herb of the genus Equisetaceae and a second herb of the Generie Juliania, family Julianiaceae , genus amphipterygium adstringens.
- solvent e.g. hot water
- about 1/2 level teaspoon of pulverized horsetail and cuachalalate mixture or about 1/4 teaspoon horsetail and about 1/4 teaspoon of cuachalalate
- various weight and volume ratios of the respective herbs were used herewith to obtain an effective amount of the combination of the two herbs.
- Exemplary ratios of the first herb to the second herb by weight include ratios of about one to about ten first herb to about one to about ten second herb.
- Exemplary ratios of the first herb by volume to the second herb include ratios of about one to about ten first herb to about one to about twenty second herb. Larger quantities of tea were ingested for longer periods of time in cases where the hemorrhoids were severe.
- EXAMPLE 4 Male subject suffering from hemmorhoids for the last twenty-five years.
- EXAMPLE 6 Forty-four year old male subject suffering from hemmorhoids for approximately one month injested two cups per day of the tea described above for a period of three days in conjunction with topical application of Anusol* cream. The hemmorhoidal symptoms disappeared.
- the present invention also includes a liquified, ready-to-serve composition for the alleviation of hemorrhoidal symptoms such as a iced tea (one made from a powdered constituent(s)) and the like.
- a variety of additions are added to the first herb of the genus Equisetaceae and the second herb of the Generie
- acidulents are selected from the group consisting of fumaric acid, citric acid, malic acid, and ascorbic acid.
- Ascorbic acid is a desired constituent of the composition both for its vitamin activity and also since it acts as an oxygen scavenger.
- Alginates are also added thereto.
- Alginates can include propylene glycol (0.1 to 0.2%) to suspend fruit pulp in a fluid of the herbs for added taste.
- Further carrageenan is also used in the present invention to improve the mouth feel of the herbal preparation.
- Furcellaran is also used at about (0.05%) to stabilize fruit pulp in the beverage where needed.
- Gum arabic is also used to optionally stabilize the preparation.
- the composition comprises a constituent selected from the group consisting of vitamins and minerals.
- vitamins contained therein include vitamin A, vitamin B complex (and the constituents thereof), vitamin C,. vitamin D, riboflavin, lactoflavin, flavin, nicotine acid, Betulin compound, ascorbic acid, thiamin, thiamine hydrochloride, thiamine chloride, betataxin, betulin, niacinamide, niacin, calcium, pantothenate, pantothenic acid, nicotinamide, pyridoxine, and tocopherol.
- Exemplary minerals include calcium, phosphorus, and magnesium, iron, iodine, zinc, and copper.
- Fiber including cellulose and other non-digestable cell-wall polymers of plant origin can also be added as needed.
- the ready to serve variant of the composition further includes an optional color additive.
- Color additives are natural color additives or artificial color additives. Color additives are selected from the group consisting of Yellow No. 5, Yellow No. 6, Red Nos.2-4, Blue Nos. 1-2, Violet No.l, Green No. 3, and Orange B.
- the color additives described herein are simply examples of the various color additives used in the present invention.
- the FD & C dyes are also used herein.
- Exemplary uses of color additives herein include adding effective amounts of color additives to the herbal preparation to obtain the following concentrations of color additive in the preparation in parts per million (ppm):
- flavor-strawberry FD&C red #40 ⁇ in the range of 50-60 ppm.
- flavor-lemon FD&C yellow #5 -- in the range of 10-20 ppm.
- ⁇ flavor-cola or root beer caramel color in the range of 200-600 ppm.
- the resultant color additive should impa ⁇ maximum color to the herbal preparation, and dissolve without showing the individual component colors. To obtain maximum color, dissolved color is added in solution followed by a moisture removing operation. The showing of individual component colors is minimized with the use or wet-dry blends.
- the herbal preparation optionally comprises a natural flavor.
- Natural flavors include essential oils, protein hydrolysate, distillates, or any products of roasting, heating, or enzymolysis which retains flavoring constituents derived from a spice, vegetable, edible yeast, herb, bark, bud, root, leaf, fruit or fruit juice concentration, or similar plant material.
- the herbal preparation is optionally substantially tableted, capsulated, liquified, and or powdered. Tableting includes exerting a high pressure on the herbal preparation to obtain a suitable size and particle distribution.
- the herbal preparation is first granulated. Granulation is accomplished by a number of suitable methods by slugging and adding a granulating liquid while mixing the herbal preparation. With slugging, the herbal preparation is run through a tablet press producing a compressed tablet. This tablet is then ground and screened to produce a granulation. An aqueous binder is then added thereto in a mixer. After agglomeration, the resulting material is then dried, ground and appropriately screened.
- EDTA is added as a preservative.
- constituents are referred to as comprising the herbal preparation it is possible that the powdered mixture consists essentially of, or only consists of these constituents. While both volume and weight ratios may be used in the practice of the invention, and both provide adequate results, volumes ratios are prefered.
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97904749A EP0874636A4 (en) | 1996-01-16 | 1997-01-15 | Tea, kit and method for treating hemorrhoids |
JP52608497A JP2001515463A (en) | 1996-01-16 | 1997-01-15 | Medicinal tea, medicinal tea kit for treating hemorrhoids, and method for treating hemorrhoidal symptoms |
AU17462/97A AU1746297A (en) | 1996-01-16 | 1997-01-15 | Tea, kit and method for treating hemorrhoids |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/585,833 US5869059A (en) | 1996-01-16 | 1996-01-16 | Herbal composition for hemorrhoid treatment |
US08/585,833 | 1996-01-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997025997A1 true WO1997025997A1 (en) | 1997-07-24 |
Family
ID=24343147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/000428 WO1997025997A1 (en) | 1996-01-16 | 1997-01-15 | Tea, kit and method for treating hemorrhoids |
Country Status (7)
Country | Link |
---|---|
US (1) | US5869059A (en) |
EP (1) | EP0874636A4 (en) |
JP (1) | JP2001515463A (en) |
CN (1) | CN1208352A (en) |
AU (1) | AU1746297A (en) |
CA (1) | CA2241935A1 (en) |
WO (1) | WO1997025997A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6228387B1 (en) * | 2000-01-27 | 2001-05-08 | Murray Borod | Integrated comprehensive hemorrhoid treatment compositions and regimen |
US8642051B2 (en) * | 2000-03-21 | 2014-02-04 | Suzanne Jaffe Stillman | Method of hydration; infusion packet system(s), support member(s), delivery system(s), and method(s); with business model(s) and Method(s) |
US6365198B1 (en) * | 2001-01-28 | 2002-04-02 | Gulf Pharmaceutical Industries | Pharmaceutical preparation for the treatment of gastrointestinal ulcers and hemorrhoids |
US7090858B2 (en) * | 2001-08-09 | 2006-08-15 | Swaminathan Jayaraman | Coated filter bag material for oral administration of medicament in liquid and methods of making same |
US20060008536A1 (en) * | 2004-07-08 | 2006-01-12 | Jdc Pharmaceutical | Pharmaceutical compositions and methods of use |
US7250445B1 (en) * | 2005-01-14 | 2007-07-31 | Ehrenpreis Eli D | Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders |
US9392814B2 (en) | 2014-06-06 | 2016-07-19 | Nicholas J. Singer | Delivery system for drinks |
USD773313S1 (en) | 2015-06-23 | 2016-12-06 | Nicholas J. Singer | Package |
Family Cites Families (25)
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US272138A (en) * | 1883-02-13 | Maey g | ||
US481815A (en) * | 1892-08-30 | Medical compound | ||
US1383896A (en) * | 1920-09-01 | 1921-07-05 | R H Chitwood | Ointment |
US1890596A (en) * | 1930-05-07 | 1932-12-13 | Zographos George | Remedy for hemorrholds |
US3062716A (en) * | 1960-02-08 | 1962-11-06 | Applic Chimiques D Etudes Et D | Method of treating hemorrhoids |
GB1056388A (en) * | 1964-04-23 | 1967-01-25 | Yves Rocher | Therapeutically useful ranunculus extracts |
US3534102A (en) * | 1967-09-06 | 1970-10-13 | David A Waldstein | Reaction products of elemental iodine and alkoxylated alkylamine oxides |
US3594473A (en) * | 1968-07-19 | 1971-07-20 | Ciba Geigy Corp | Anti-haemorrhoidally active preparations and the use of a d-glucofuranoside in such preparations |
US3781424A (en) * | 1970-07-21 | 1973-12-25 | E Ponvert | Hemorrhoid treatment preparation produced from hot cherry peppers |
US4118480A (en) * | 1973-02-09 | 1978-10-03 | Charles V. Stoelker | Pharmaceutical preparation for treating hemorrhoids and anal fissures |
US3935310A (en) * | 1974-03-07 | 1976-01-27 | Homan John D | Remedy for treatment of hemorrhoids |
ES456574A1 (en) * | 1977-03-07 | 1978-02-16 | Rocador Sa | Quercetin pentamethyl carbamate and a process for its preparation |
US4169143A (en) * | 1978-07-10 | 1979-09-25 | Irving Haimowitz | Method for treating hemorrhoid symptoms and composition for use therein |
US4192866A (en) * | 1978-10-10 | 1980-03-11 | Ralph Anderson | Anorectal medication |
US4265887A (en) * | 1979-12-11 | 1981-05-05 | Breskman Joseph S | Composition and method for treatment of hemorrhoids |
US4383986A (en) * | 1981-08-17 | 1983-05-17 | Ortho Pharmaceutical Corporation | Hemorrhoidal compositions |
FR2581310B1 (en) * | 1985-05-02 | 1988-09-23 | Natura Medica Laboratoires | THERAPEUTIC COMPOSITION COMPRISING A-LINOLENIC ACID AND A COMPOUND CAPABLE OF PROMOTING ACID THROUGH THE CELL MEMBRANE AND PLANT EXTRACT COMPRISING THE ACID AND THE COMPOUND |
US4626433A (en) * | 1985-05-20 | 1986-12-02 | Preparation Gold, Inc. | Remedy for hemorrhoids |
US4761285A (en) * | 1986-10-28 | 1988-08-02 | Athanasios Vasiliou | Composition for relief and treatment of hemorrhoids |
US4945084A (en) * | 1987-07-08 | 1990-07-31 | Norman Oksman | Method and composition for topically treating anorectal or other dermal wounds |
US5196405A (en) * | 1987-07-08 | 1993-03-23 | Norman H. Oskman | Compositions and methods of treating hemorrhoids and wounds |
IT8947616A0 (en) * | 1989-02-06 | 1989-02-06 | Verde Giancarlo Umberto | PREPARATION FOR THE TREATMENT AND CURE OF HEMORRHOIDS |
US5234914A (en) * | 1991-06-11 | 1993-08-10 | Patent Biopharmaceutics, Inc. | Methods of treating hemorrhoids and anorecial disease |
US5266571A (en) * | 1992-01-09 | 1993-11-30 | Amer Moh Samir | Treatment of hemorrhoids with 5-HT2 antagonists |
DE69327432T2 (en) * | 1992-02-07 | 2000-05-18 | Kaken Pharma Co Ltd | MEDICINE FOR Wounds and Hemorrhoid |
-
1996
- 1996-01-16 US US08/585,833 patent/US5869059A/en not_active Expired - Fee Related
-
1997
- 1997-01-15 EP EP97904749A patent/EP0874636A4/en not_active Withdrawn
- 1997-01-15 WO PCT/US1997/000428 patent/WO1997025997A1/en not_active Application Discontinuation
- 1997-01-15 CA CA002241935A patent/CA2241935A1/en not_active Abandoned
- 1997-01-15 AU AU17462/97A patent/AU1746297A/en not_active Abandoned
- 1997-01-15 JP JP52608497A patent/JP2001515463A/en active Pending
- 1997-01-15 CN CN97191714A patent/CN1208352A/en active Pending
Non-Patent Citations (5)
Title |
---|
ACTA CRYST., 1978, SORIANO-GARCIA et al., "Structure and Stereochemistry of the Methyl Ester of (5a, 13a,14beta,17a,20s,24Z)-3-Oxolanosta-7,24-d ien-26-oic Acid (Masticadienonic Acid)", pages 990-992. * |
FOSTER et al., "A Field Guide to Medicinal Plants", BOSTON: HOUGHTON MIFFLIN, 1990, page 304. * |
JOURNAL OF ETHNOPHARMACOLOGY, 1991, Vol. 34, MATA et al., "Long-chain Phenols from the Bark of Amphypterygium Adstringens", pages 147-154. * |
ODY PENELOPE, "The Complete Medicinal Herbal", LONDON: DORLING KINDERSLEY, 1993, page 55. * |
See also references of EP0874636A4 * |
Also Published As
Publication number | Publication date |
---|---|
EP0874636A1 (en) | 1998-11-04 |
AU1746297A (en) | 1997-08-11 |
JP2001515463A (en) | 2001-09-18 |
CA2241935A1 (en) | 1997-07-24 |
CN1208352A (en) | 1999-02-17 |
EP0874636A4 (en) | 2000-03-29 |
US5869059A (en) | 1999-02-09 |
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