WO1991015200A3 - Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases - Google Patents
Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases Download PDFInfo
- Publication number
- WO1991015200A3 WO1991015200A3 PCT/GB1991/000517 GB9100517W WO9115200A3 WO 1991015200 A3 WO1991015200 A3 WO 1991015200A3 GB 9100517 W GB9100517 W GB 9100517W WO 9115200 A3 WO9115200 A3 WO 9115200A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carminic acid
- cancer
- compounds
- trinitrobenzenes
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR919106310A BR9106310A (en) | 1990-04-03 | 1991-04-03 | FORMULATION FOR NEOPLASM THERAPY OR PROPHYLAXIS OR VIRAL INFECTION PHARMACEUTICAL OR VETERINARY, RADIAL OR COMPOUND FORMULATION, FORMATION FOR VIRAL INFECTION AND AMPHRAKINONE GLYCOSIDE THERAPY |
JP3506514A JPH06501449A (en) | 1990-04-03 | 1991-04-03 | Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases |
AU75604/91A AU662883B2 (en) | 1990-04-03 | 1991-04-03 | Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases |
MC91GB9100517D MC2246A1 (en) | 1990-04-03 | 1991-04-03 | USE OF TRINITROBENZENES OR CARMINIC ACID IN THE TREATMENT OF CANCER OR VIRAL DISEASES |
NO92923824A NO923824L (en) | 1990-04-03 | 1992-10-01 | USE OF TRINITROBENZENES OR CARCAMIC ACID IN TREATMENT OF CANCER OR VIRUS DISEASES |
FI924475A FI924475A (en) | 1990-04-03 | 1992-10-05 | ANIMAL TRENDS WITH CARMINSHINE VID BEHANDLING AV CANCER VIRUS BETINGADE SJUKDOMAR |
LVP-92-149A LV10574B (en) | 1990-04-03 | 1992-10-05 | The therapeutic use of low concentrations of trinitrobenzene, carminic acid and their derivatives as anti-cancer and anti-viral agents |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9007453.5 | 1990-04-03 | ||
GB909007453A GB9007453D0 (en) | 1990-04-03 | 1990-04-03 | Tumour therapy |
GB909012166A GB9012166D0 (en) | 1990-05-31 | 1990-05-31 | Hydrazine derivatives for cancer therapy |
GB9012166.6 | 1990-05-31 | ||
GB9103075.9 | 1991-02-13 | ||
GB919103075A GB9103075D0 (en) | 1991-02-13 | 1991-02-13 | Trinitrobenzene derivatives and their therapeutic use |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1991015200A2 WO1991015200A2 (en) | 1991-10-17 |
WO1991015200A3 true WO1991015200A3 (en) | 1992-03-05 |
Family
ID=27265028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1991/000517 WO1991015200A2 (en) | 1990-04-03 | 1991-04-03 | Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0524212A1 (en) |
JP (1) | JPH06501449A (en) |
AU (1) | AU662883B2 (en) |
BR (1) | BR9106310A (en) |
CA (1) | CA2079803A1 (en) |
FI (1) | FI924475A (en) |
HU (1) | HUT62785A (en) |
LV (1) | LV10574B (en) |
MC (1) | MC2246A1 (en) |
NO (1) | NO923824L (en) |
WO (1) | WO1991015200A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9103075D0 (en) * | 1991-02-13 | 1991-03-27 | Washington Odur Ayuko | Trinitrobenzene derivatives and their therapeutic use |
US5412123A (en) * | 1993-02-08 | 1995-05-02 | Glycomed Incorporated | Anthraquinone and anthracene derivatives as inhibitors of the cell-adhesion molecules of the immune system |
GB2312375B (en) * | 1993-05-21 | 1998-02-25 | Radopath Ltd | Agents for treatment of cancer |
DZ1781A1 (en) * | 1993-05-21 | 2002-02-17 | Radopah Ltd | Arylating agents. |
GB9310520D0 (en) | 1993-05-21 | 1993-07-07 | Radopath Ltd | Arylating agents |
ATE198273T1 (en) * | 1994-03-17 | 2001-01-15 | Radopath Pharmaceuticals Inter | ACTIVE SUBSTANCE AGAINST VIRUSES AND CANCER |
WO1996029067A1 (en) * | 1995-03-17 | 1996-09-26 | Radopath Limited | Anti-viral and anti-cancer agents |
GB9615619D0 (en) * | 1996-03-18 | 1996-09-04 | Radopath Ltd | Costimulation of TcR/CD3-induced T-Lymphocytes |
WO1999029706A2 (en) * | 1997-12-08 | 1999-06-17 | Glycomed Incorporated | DISALICYLATE ANALOG BASED SIALYL LEWISx MIMETICS |
CN112424291A (en) * | 2018-07-17 | 2021-02-26 | 皮利公司 | Anthraquinone derivatives and their use as colorants |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4032659A (en) * | 1969-03-20 | 1977-06-28 | American Home Products Corporation | Method of viral chemoprophylaxis |
US4724230A (en) * | 1982-09-17 | 1988-02-09 | Therapeutical Systems Corp. | Method for producing oncolysis |
EP0314580A1 (en) * | 1987-10-30 | 1989-05-03 | Institut Pasteur | Use of nitrophenyl groups for stimulating the capability of incorporation of a drug into the sensitive cells of a host |
-
1991
- 1991-04-03 CA CA002079803A patent/CA2079803A1/en not_active Abandoned
- 1991-04-03 BR BR919106310A patent/BR9106310A/en not_active Application Discontinuation
- 1991-04-03 WO PCT/GB1991/000517 patent/WO1991015200A2/en not_active Application Discontinuation
- 1991-04-03 EP EP91907059A patent/EP0524212A1/en not_active Withdrawn
- 1991-04-03 JP JP3506514A patent/JPH06501449A/en active Pending
- 1991-04-03 HU HU923148A patent/HUT62785A/en unknown
- 1991-04-03 MC MC91GB9100517D patent/MC2246A1/en unknown
- 1991-04-03 AU AU75604/91A patent/AU662883B2/en not_active Ceased
-
1992
- 1992-10-01 NO NO92923824A patent/NO923824L/en unknown
- 1992-10-05 FI FI924475A patent/FI924475A/en not_active Application Discontinuation
- 1992-10-05 LV LVP-92-149A patent/LV10574B/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4032659A (en) * | 1969-03-20 | 1977-06-28 | American Home Products Corporation | Method of viral chemoprophylaxis |
US4724230A (en) * | 1982-09-17 | 1988-02-09 | Therapeutical Systems Corp. | Method for producing oncolysis |
EP0314580A1 (en) * | 1987-10-30 | 1989-05-03 | Institut Pasteur | Use of nitrophenyl groups for stimulating the capability of incorporation of a drug into the sensitive cells of a host |
Non-Patent Citations (13)
Title |
---|
ANTICANCER RESEARCH, vol. 7, no. 4B, July-August 1987, (Athens, GR), T. FUJII et al.: "Effect of PSK on prohibited immunity of splenectomized mice", pages 845-848, see results; discussion * |
BIOORGANIC CHEMISTRY, vol. 8, no. 1, March 1979, (London, GB), J.W. LOWN et al.: "Reactions of the antitumor agent carminic acid and derivatives with DNA", pages 17-24, see abstract * |
COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES, vol. 167, no. 8, 1973, (Paris, FR), C. DEBY et al.: "Influence d'un régime enrichi en acides gras non saturés sur la toxicité du diphénylpicrylhydrazyl", pages 1302-1305, see abstract * |
IMMUNITY TO CANCER. II. PROCEEDINGS OF THE 2ND CONFERENCE ON IMMUNITY TO CANCER, Williamsburg, Virginia, 9-11 November 1987, Alan R. Liss, Inc., (New York, US), A.M. FRIEDMAN et al.: "Prevention of tumor growth and enhancement of cell-mediated immunity by an antigen-specific contrasuppressor factor fram a T cell hybridoma", pages 281-288, see the whole article * |
IMMUNOLOGY, vol. 51, no. 4, April 1984, (Oxford, GB), I. ENANDER et al.: "Mononuclear cells, mast cells and mucous cells as part of the delayed hypersensitivity response to aerosolized antigen in mice", pages 661-668, see abstract * |
IMMUNOLOGY, vol. 54, no. 2, February 1985, (Oxford, GB), P.M. COMOGLIO et al.: "Enhancement of immunity against RSV-induced sarcomas by generation of hapten-reactive helper T lymphocytes", pages 289-295, see the whole article, esp. page 291, figure 1 * |
IMMUNOLOGY, vol. 66, no. 4, April 1989, (Oxford, GB), I. KIMBER et al.: "Regulation of lymphocyte proliferation in contact sensitivity: homeostatic mechanisms and a possible explanation of antigenic competition", pages 577-582, see the whole article * |
LIFE SCIENCES, vol. 42, no. 15, 1988, (Oxford, GB), J.M. JAMISON et al.: "Enhancement of the antiviral and interferon-inducing activities of poly r(A-U) by carminic acid", pages 1477-1483, see page 1474, table 1 * |
PATENT ABSTRACTS OF JAPAN, vol. 5, no. 102 (C-61)[774], 2 July 1981, & JP,A,5643210 (KOUTAKU HAYASHI) 21 April 1981, see abstract * |
REV. CHIR., ONCOL., RADIOL., ORL, OFTALMOL., STOMATOL.: ONCOL., vol. 28, no. 2, 1989, (RO), N. MIHAIL et al.: "Cytostatic action of histological stains for nucleic acids", pages 115-121, see pages 115-116 * |
REVUE EUROPEENNE D'ETUDES CLINIQUES ET BIOLOGIQUES, vol. 15, no. 6, 1970, (Paris, FR), C. DEBY et al.: "Effect of a stable free-radical on the survival of x-irradiated mice", pages 678-682, see results * |
THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 156, no. 1, 1st July 1982, (New York, US), W.R. THOMAS et al.: "Hapten-specific T cell lines mediating delayed hypersensitivity to contact-sensitizing agents", pages 300-305, see results; discussion * |
ZHURNAL OBSCHEI KHIMII, vol. 32, no. 12, December 1962, (SU), M.A. IKRINA et al.: "Investigations in the field of the chemistry of free radicals of the hydrazine series VIII" (applicant's translation), pages 3952-3957, see the whole article (cited in the application) * |
Also Published As
Publication number | Publication date |
---|---|
HU9203148D0 (en) | 1992-12-28 |
NO923824L (en) | 1992-11-26 |
WO1991015200A2 (en) | 1991-10-17 |
NO923824D0 (en) | 1992-10-01 |
HUT62785A (en) | 1993-06-28 |
CA2079803A1 (en) | 1991-10-04 |
AU662883B2 (en) | 1995-09-21 |
LV10574A (en) | 1995-04-20 |
MC2246A1 (en) | 1993-03-25 |
FI924475A0 (en) | 1992-10-05 |
BR9106310A (en) | 1993-04-20 |
JPH06501449A (en) | 1994-02-17 |
FI924475A (en) | 1992-10-05 |
AU7560491A (en) | 1991-10-30 |
LV10574B (en) | 1995-08-20 |
EP0524212A1 (en) | 1993-01-27 |
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