USRE39335E1 - Surgical graft/stent system - Google Patents

Surgical graft/stent system Download PDF

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Publication number
USRE39335E1
USRE39335E1 US10/142,338 US14233802A USRE39335E US RE39335 E1 USRE39335 E1 US RE39335E1 US 14233802 A US14233802 A US 14233802A US RE39335 E USRE39335 E US RE39335E
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sheath
graft
tubular
branch tube
members
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US10/142,338
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Anthony Walter Anson
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Anson Medical Ltd
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Anson Medical Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/92Stents in the form of a rolled-up sheet expanding after insertion into the vessel, e.g. with a spiral shape in cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/065Y-shaped blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • A61F2002/072Encapsulated stents, e.g. wire or whole stent embedded in lining
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • A61F2002/075Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0019Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0023Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
    • A61F2210/0042Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply using a fluid, e.g. circulating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0041Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/005Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body

Definitions

  • This invention relates to a graft/stent system for use in human or animal surgery.
  • a graft/stent is disclosed in EP 0326426A, which describes an artificial blood vessel in the form of a tubular sheath having a ring-like member located at each of its ends.
  • EP 0461791A is an aortic graft with one of its tubular ends divided into two branches.
  • tubular graft/stent as specified in claim 1 .
  • tubular graft/stent as specified in claim 9 .
  • the invention proposes a medical tubular graft stent which comprises a tubular sheath having at intervals along its length a plurality of ring-like members, wherein said members are attached to the sheath around their respective circumferences and are made of a shape memory material, so that when said members change shape, the sheath adopts a new cross-section in conformity with them along its whole length.
  • this provides a compliant tubular sheath, into which a series of open rings are integrated.
  • the rings act as rigidising members and are capable of being radially compressed by mechanical forces in the martensitic phase so as to reduce the diameter, and of then returning in the austenitic phase to a memorised, larger diameter by a thermal effect.
  • the invention proposes a tubular graft comprising a tubular sheath having a branch tube which is sufficiently flexible to be inverted so as to be housed within the sheath during an insertion operation in a human or animal body, and to be redeployed as a branch after said operation.
  • the sheath and/or the branch tube may employ annular rigid members of a shape memory material, as explained above.
  • the members are preferably discontinuous, e.g. a ring with a break so as to facilitate compression and re-expansion.
  • FIG. 1 shows a perspective view of a first form of graft
  • FIG. 2 shows its compressed form in the martensitic phase in transverse cross-section
  • FIG. 3 shows its expanded form in the austentitic phase
  • FIG. 4 shows an embodiment having a branch tube in its inverted position
  • FIG. 5 shows the FIG. 4 version with the branch tube deployed
  • FIG. 6 shows a further embodiment of the present invention.
  • FIGS. 7 and 8 show enlarged and developed views of two versions of an overlap region.
  • a compliant tube 10 can be constructed of any flexible material such as cloth, polymers, elastomers or gels. Secured within the compliant tube are a plurality of expandable or contractible open rings 11 composed of shape memory alloy material.
  • the shape memory alloy rings give structural support to the compliant tubular sheath and are oriented transverse to the axis of the tube.
  • the cube is circumferentially closed by the overlap 20 , but has free edges 21 , 22 .
  • the edges 21 , 22 might but one another, but this does not provide as much certainty that the tube wall is closed.
  • the compliant tube 10 can be generated by fabrication methods, or an “open” tube could be made by using flat sheets whose shape is established by the shape memory alloy rings.
  • the tubular form might also use sheets of dissimilar materials.
  • the cube may be produced in continuous lengths and cut off as needed.
  • the shape memory alloy rings can be retained by casting a suitable compliant material around the ring, by adhesive bonding, sewing or by generating a series of pockets within which the rings may be held by welding, sewing, mechanical fixation or adhesive bonding.
  • the rings 11 are in a single piece, but could be in two or more accurate sections.
  • FIGS. 2 and 3 show the compressed (e.g. spiral or rolled-up) and expanded forms of the tube.
  • the tubular graft/stent is radially compressed down to 5.5 mm outside diameter before the device is fitted into the human body via a delivery catheter.
  • the outside diameter might be up to 4 cm.
  • the device described is suitable for a number of minimally invasive surgical techniques or may substantially reduce trauma associated with the introduction of implanted medical devices within a living organism.
  • a single, plain tube (known as a tubular graft) with integrated expandable contractible rings (known as stents) as described is inserted into a occluded fluid carrying vessel or a vessel that has a structure.
  • heat from the human body or a heated fluid introduced
  • the rings will expand to a pre-determined position as seen in FIG. 3 , the outside dimensions of which will be slightly larger than the inner dimensions of the fluid carrying vessel. Frictional effects will normally retain the graft/stent in position.
  • the shape memory alloy may be arranged so that when a thermal transition point (memory re-call) is reached selected sections of the alloy will protrude from the metals surface presenting a substantial fixation force.
  • a thermal transition point memory re-call
  • One or more of the alloy rings could be configured with this additional retention feature.
  • This device may find applications in surgical repair or maintenance procedure for the human body or other animal species. Gastro-intestinal system connections, oesophageal cancer, aneurysms, coronary by-pass connections and other vascular by-pass or shunt procedures could employ the stent/graft device.
  • the dynamic properties of the rings expand the graft/stent within the body to effect an opening of constricted or occluded vessel.
  • the outer graft stent would assist in preventing occlusive material from once again entering the vessel.
  • the complaint sheath will also exclude tumorous growth, maintaining luminal patency.
  • the tubular graft with in integrated shape memory alloy rings may be a simple tube-like form as described or could be a manifold system having a main tube 13 from which one or substantial numbers of connections 14 may be made, as seen in FIGS. 4 and 5 .
  • the single a tube or manifold will allow fluids to pass in or out of the said connections, to or from the main tube structure.
  • the branches extending from the main body can be of uniform cross-section or of tapering construction.
  • a graft of the type described might be simply bifurcated or may have numerous smaller or larger tubes of similar construction, attached to the main tube body.
  • the branches attached to the body of the device may have a similar shape memory alloy ring configuration.
  • Each branch 14 can be inverted so as to fit within the main tube. Under these conditions, the whole assembly can be radially compressed, the manifold system now appearing as a single tube for initial insertion via a catheter.
  • a suitable cord to 15 is connected to the inverted branch enabling it/them to be re-inverted by pulling the cord, as shown in FIG. 5 .
  • the rings nearer to the main tube are largest and are progressively smaller towards the end, to allow the inversion to occur.
  • the shape memory alloy rings When warmed, the shape memory alloy rings will expand to a pre-determined position. If employed in a surgical repair, forces exerted by the shape memory alloy rings will be of sufficient magnitude to open an occluded vessel thus enabling appropriate fluid flows to continue.
  • the compliant outer sheath would enable radial or axial movement of the vessel to occur. This might be the case if the stent/graft were positioned in an osophagus that had radially disposed tumours. Peristalsis effects used to assist transportation of food and liquids in the human body would need to be maintained in oesophageal dysfunctional problems.
  • the covered or sheathed stent system would exclude tumorous in-growth and still enable peristalsis to occur.
  • the compliant could be 0.050 mm polyurethane, polyester or polythene.
  • the shape memory material may be a metal alloy with this property, or alternatively certain mouldable plastics materials such as homopolymers of lactide or glycolide, or copolymers of lactide and glycolide.
  • the invention is also considered to include a graft with a side tube which does not employ stents of shape memory material.
  • the ring-like rigid members 11 can also be fabricated from elastic materials such as stainless steel or the super-elastic forms of nickel-titanium alloys. In this case the implant is constrained within in outer sheath after whose removal the graft will expand to adopt its final shape.
  • the flexible tubular sheath can contain slits or openings 23 which are approximately parallel to the ring-like members and which allow greater flexion of the implant without kinking the sheath.
  • the arrangement of the slits or openings can be varied with the application and can be positioned to be all on one side of the cube 23 , on alternating sites 24 or spirally arranged along the sheath ( 25 ). Other arrangements are possible.
  • the overlap 20 can be designed to have one of three properties:
  • the overlap can be left to slide freely over itself, permitting the graft assembly to be contracted by muscles in the vessel or to allow pressure pulses in arterial blood, arising from the heartbeat, to be transmitted to the artery wall.
  • the action of pressure pulses is involved in maintaining the vasomotor tone in blood vessels.
  • the mating surfaces of the overlapping part of the sheath can be coated to reduce friction and wear with materials such as PTFE or diamond-like coatings.
  • the overlap can incorporate a ratchet-like mechanism which will allow the diameter of the ring-like rigid member to expand but not to contract. This will guarantee that the lumen of the vessel will be maintained to a minimum diameter and will allow the ring to be locked against the inside of the vessel wall to prevent migration of the device.
  • the overlap can incorporate a ratchet-like mechanism which will allow the diameter of the ring-like rigid member not to exceed a specified diameter. This is of use where the vessel is fragile and can be exposed to high intraluminal pressures.
  • the ratchet-like mechanism can be incorporated onto the walls of the sheath by moulding, machining, or attaching ratchet components.
  • the ratchet mechanism can be formed in the ends of the ring-like member and can be either permanently present or deployed by the action of thermal memory.
  • An implant can be assembled which incorporates a combination of all three types of overlap mechanism so that for instance, the distal ends of the graft can use ratchet expanding rings to lock the device in place, while the main body of the graft uses alternating sliding and diameter-limiting rings to allow limited transmission of pulsatility while restricting the maximum diameter of the graft.
  • the benefit of the graft can be increased by incorporating coatings onto its inner or outer surfaces.
  • These coatings can be biomimetics such as phosphorylcholines and proteins, organic biocompatibles such as hydrophilic plastics and inorganic coatings, such as diamond-like carbon.
  • the coatings can be used to be thrombus-resistant, encrustation resistant or to promote cellular ingrowth.
  • the coatings can be used to release locally acting pharmacological agents and they can be multiply layered.
  • Deployment of the inverted segment 14 can be achieved by adding a short handle, tab or strip to the distal end of the side branch which can be engaged by a snare, forceps or similar engagement means.

Abstract

A tubular graft/stent includes a tubular sheath (10) having at intervals along its length a plurality of ring-like rigid members (11), which are attached to the sheath around their respective circumferences and are made of a shape memory material, so that when the members (11) change shape the sheath (10) adopts a new cross section in conformity with them along its whole length. The members may be discontinuous to allow the adoption of a contracted shape in the martensitic phase and an expanded shape in the austenitic phase. A graft may also have a side tube (14) which can be inverted so as to be housed within the sheath.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation of International (PCT) Patent Application Patent Application PCT/GB96/02212 filed 6 Sep. 1996.
BACKGROUND Field of the Invention
This invention relates to a graft/stent system for use in human or animal surgery. One example of this type of graft/stent is disclosed in EP 0326426A, which describes an artificial blood vessel in the form of a tubular sheath having a ring-like member located at each of its ends. Another example, disclosed in EP 0461791A, is an aortic graft with one of its tubular ends divided into two branches.
SUMMARY
According to an aspect of the present invention, there is provided a tubular graft/stent as specified in claim 1.
According to another aspect of the present invention, there is provided a tubular graft/stent as specified in claim 9.
The invention proposes a medical tubular graft stent which comprises a tubular sheath having at intervals along its length a plurality of ring-like members, wherein said members are attached to the sheath around their respective circumferences and are made of a shape memory material, so that when said members change shape, the sheath adopts a new cross-section in conformity with them along its whole length.
Preferably, this provides a compliant tubular sheath, into which a series of open rings are integrated. The rings act as rigidising members and are capable of being radially compressed by mechanical forces in the martensitic phase so as to reduce the diameter, and of then returning in the austenitic phase to a memorised, larger diameter by a thermal effect.
In a further aspect, the invention proposes a tubular graft comprising a tubular sheath having a branch tube which is sufficiently flexible to be inverted so as to be housed within the sheath during an insertion operation in a human or animal body, and to be redeployed as a branch after said operation. The sheath and/or the branch tube may employ annular rigid members of a shape memory material, as explained above. In all cases, the members are preferably discontinuous, e.g. a ring with a break so as to facilitate compression and re-expansion.
In order that the invention shall be clearly understood, several exemplary embodiments thereof will now be described with references to the accompanying drawings, in which:
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 shows a perspective view of a first form of graft,
FIG. 2 shows its compressed form in the martensitic phase in transverse cross-section;
FIG. 3 shows its expanded form in the austentitic phase;
FIG. 4 shows an embodiment having a branch tube in its inverted position;
FIG. 5 shows the FIG. 4 version with the branch tube deployed;
FIG. 6 shows a further embodiment of the present invention; and
FIGS. 7 and 8 show enlarged and developed views of two versions of an overlap region.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
An exemplary general arrangement is shown in FIG. 1. A compliant tube 10 can be constructed of any flexible material such as cloth, polymers, elastomers or gels. Secured within the compliant tube are a plurality of expandable or contractible open rings 11 composed of shape memory alloy material. The shape memory alloy rings give structural support to the compliant tubular sheath and are oriented transverse to the axis of the tube. The cube is circumferentially closed by the overlap 20, but has free edges 21, 22. Alternatively, the edges 21, 22 might but one another, but this does not provide as much certainty that the tube wall is closed.
The compliant tube 10 can be generated by fabrication methods, or an “open” tube could be made by using flat sheets whose shape is established by the shape memory alloy rings. The tubular form might also use sheets of dissimilar materials. The cube may be produced in continuous lengths and cut off as needed.
The shape memory alloy rings can be retained by casting a suitable compliant material around the ring, by adhesive bonding, sewing or by generating a series of pockets within which the rings may be held by welding, sewing, mechanical fixation or adhesive bonding. In the embodiment shown, the rings 11 are in a single piece, but could be in two or more accurate sections.
FIGS. 2 and 3 show the compressed (e.g. spiral or rolled-up) and expanded forms of the tube. The tubular graft/stent is radially compressed down to 5.5 mm outside diameter before the device is fitted into the human body via a delivery catheter. In its expanded form, the outside diameter might be up to 4 cm.
The device described is suitable for a number of minimally invasive surgical techniques or may substantially reduce trauma associated with the introduction of implanted medical devices within a living organism. A single, plain tube (known as a tubular graft) with integrated expandable contractible rings (known as stents) as described is inserted into a occluded fluid carrying vessel or a vessel that has a structure. When appropriately positioned via the catheter, heat from the human body (or a heated fluid introduced) will cause the latent geometry of the shape memory alloy to be re-called. Under these circumstances the rings will expand to a pre-determined position as seen in FIG. 3, the outside dimensions of which will be slightly larger than the inner dimensions of the fluid carrying vessel. Frictional effects will normally retain the graft/stent in position. However, the shape memory alloy may be arranged so that when a thermal transition point (memory re-call) is reached selected sections of the alloy will protrude from the metals surface presenting a substantial fixation force. One or more of the alloy rings could be configured with this additional retention feature.
This device may find applications in surgical repair or maintenance procedure for the human body or other animal species. Gastro-intestinal system connections, oesophageal cancer, aneurysms, coronary by-pass connections and other vascular by-pass or shunt procedures could employ the stent/graft device.
The dynamic properties of the rings expand the graft/stent within the body to effect an opening of constricted or occluded vessel. The outer graft stent would assist in preventing occlusive material from once again entering the vessel. The complaint sheath will also exclude tumorous growth, maintaining luminal patency.
The tubular graft with in integrated shape memory alloy rings may be a simple tube-like form as described or could be a manifold system having a main tube 13 from which one or substantial numbers of connections 14 may be made, as seen in FIGS. 4 and 5. The single a tube or manifold will allow fluids to pass in or out of the said connections, to or from the main tube structure. The branches extending from the main body can be of uniform cross-section or of tapering construction.
A graft of the type described might be simply bifurcated or may have numerous smaller or larger tubes of similar construction, attached to the main tube body. The branches attached to the body of the device may have a similar shape memory alloy ring configuration. Each branch 14 can be inverted so as to fit within the main tube. Under these conditions, the whole assembly can be radially compressed, the manifold system now appearing as a single tube for initial insertion via a catheter. A suitable cord to 15 is connected to the inverted branch enabling it/them to be re-inverted by pulling the cord, as shown in FIG. 5. Preferably, the rings nearer to the main tube are largest and are progressively smaller towards the end, to allow the inversion to occur.
When warmed, the shape memory alloy rings will expand to a pre-determined position. If employed in a surgical repair, forces exerted by the shape memory alloy rings will be of sufficient magnitude to open an occluded vessel thus enabling appropriate fluid flows to continue.
The compliant outer sheath would enable radial or axial movement of the vessel to occur. This might be the case if the stent/graft were positioned in an osophagus that had radially disposed tumours. Peristalsis effects used to assist transportation of food and liquids in the human body would need to be maintained in oesophageal dysfunctional problems. The covered or sheathed stent system would exclude tumorous in-growth and still enable peristalsis to occur.
The compliant could be 0.050 mm polyurethane, polyester or polythene. The shape memory material may be a metal alloy with this property, or alternatively certain mouldable plastics materials such as homopolymers of lactide or glycolide, or copolymers of lactide and glycolide.
The invention is also considered to include a graft with a side tube which does not employ stents of shape memory material. Thus in addition to shape memory materials, the ring-like rigid members 11 can also be fabricated from elastic materials such as stainless steel or the super-elastic forms of nickel-titanium alloys. In this case the implant is constrained within in outer sheath after whose removal the graft will expand to adopt its final shape.
In the embodiment of FIG. 6, which is of particular benefit in stenting tortuous vessels such as the male urethra, the flexible tubular sheath can contain slits or openings 23 which are approximately parallel to the ring-like members and which allow greater flexion of the implant without kinking the sheath. The arrangement of the slits or openings can be varied with the application and can be positioned to be all on one side of the cube 23, on alternating sites 24 or spirally arranged along the sheath (25). Other arrangements are possible.
The overlap 20 can be designed to have one of three properties:
1) The overlap can be left to slide freely over itself, permitting the graft assembly to be contracted by muscles in the vessel or to allow pressure pulses in arterial blood, arising from the heartbeat, to be transmitted to the artery wall. The action of pressure pulses is involved in maintaining the vasomotor tone in blood vessels.
The mating surfaces of the overlapping part of the sheath can be coated to reduce friction and wear with materials such as PTFE or diamond-like coatings.
2) As shown in FIG. 7, the overlap can incorporate a ratchet-like mechanism which will allow the diameter of the ring-like rigid member to expand but not to contract. This will guarantee that the lumen of the vessel will be maintained to a minimum diameter and will allow the ring to be locked against the inside of the vessel wall to prevent migration of the device.
3) As shown in FIG. 8, the overlap can incorporate a ratchet-like mechanism which will allow the diameter of the ring-like rigid member not to exceed a specified diameter. This is of use where the vessel is fragile and can be exposed to high intraluminal pressures.
The ratchet-like mechanism can be incorporated onto the walls of the sheath by moulding, machining, or attaching ratchet components. Alternatively, the ratchet mechanism can be formed in the ends of the ring-like member and can be either permanently present or deployed by the action of thermal memory.
An implant can be assembled which incorporates a combination of all three types of overlap mechanism so that for instance, the distal ends of the graft can use ratchet expanding rings to lock the device in place, while the main body of the graft uses alternating sliding and diameter-limiting rings to allow limited transmission of pulsatility while restricting the maximum diameter of the graft.
The benefit of the graft can be increased by incorporating coatings onto its inner or outer surfaces. These coatings can be biomimetics such as phosphorylcholines and proteins, organic biocompatibles such as hydrophilic plastics and inorganic coatings, such as diamond-like carbon. The coatings can be used to be thrombus-resistant, encrustation resistant or to promote cellular ingrowth. In addition, the coatings can be used to release locally acting pharmacological agents and they can be multiply layered.
Deployment of the inverted segment 14 can be achieved by adding a short handle, tab or strip to the distal end of the side branch which can be engaged by a snare, forceps or similar engagement means.

Claims (16)

1. A tubular graft/stent comprising:
a tubular sheath that is graft/stent; and
an integral branch tube having an end fixed to the tubular sheath at an opening in a side wall of the tubular sheath, wherein the branch tube is a graft/stent along its entire length, the branch tube comprising a plurality of rigid ring-like members being of progressively smaller size in the direction progressively away from the tubular sheath, and the branch tube being sufficiently flexible to be fully inverted along its entire length so as to be fully housed within the tubular sheath during an insertion operation in a human or animal body, and to be redeployed as a branch after insertion operation.
2. A tubular graft/stent according to claim 1, wherein the rigid ring-like members are made of a shape memory material, so that when said members change shape the sheath adopts a new cross-section in conformity with them along its whole length.
3. A tubular graft/stent according to claim 1, wherein the rigid members are attached to the sheath around their respective peripheries.
4. A tubular graft/stent according to claim 1, wherein said members are discontinuous to allow them to adopt a contracted shape in the martensitic phase, and an expanded shape of larger circumference in the austenitic phase.
5. A tubular graft/stent according to claim 1, wherein said members can be caused to adopt a spiral form as the contracted shape and a generally circular form as the expanded shape.
6. A tubular graft/stent according to claim 1, wherein the rigid ring-like members are embedded in a compliant material that is cast around said members to form the sheath.
7. A tubular graft/stent according to claim 1, wherein the rigid ring-like members are held in pockets formed in the material of the sheath.
8. A tubular graft/stent according to claim 1, wherein the members are trapped between two layers of material which together form the sheath.
9. A tubular graft/stent according to claim 1, wherein the members include portions which project from the outer surface of the graft in its new cross-section, such projecting portions forming anchors for locating the graft in position in a body.
10. A tubular graft/stent according to claim 1, wherein the branch tube has a draw string attached at its free end such that when inverted into the sheath the draw string may be pulled to redeploy the branch tube outside the sheath.
11. A method of inserting a graft/stent having a tubular sheath which is a graft/stent and an attached integral branch tube that is also a graft/stent along its entire length, the method comprising:
fully inverting said branch tube along its entire length to place said branch tube fully within said tubular sheath for insertion in a body;
inserting said graft/stent into said body; and
pulling said branch tube out of said tubular sheath in said body, wherein pulling said tubular branch tube re-inverts said branch tube and leaves said branch tube attached to said tubular sheath.
12. The method of claim 11, wherein pulling said branch tube comprises:
engaging a cord on a distal end of said branch tube; and
pulling said cord to deploy said branch tube within said body.
13. The method of claim 12, wherein said cord is selected from the group consisting of a draw string, short handle, tab, and strip.
14. The method of claim 11 wherein the sheath includes at least one ring-like member along its length which is made of a shape memory material, and wherein the method further comprises the step of cooling the member.
15. The method of claim 11 wherein the sheath includes at least one ring-like member along its length, the member having a variable shape wherein it may be at least partially coiled, wherein the method further comprises the step of uncoiling the member.
16. The method of claim 11 wherein the sheath is defined by material which is at least partially coiled, wherein the method further comprises the step of uncoiling the sheath from a small-diameter state to a large-diameter state.
US10/142,338 1995-09-08 2002-05-09 Surgical graft/stent system Expired - Lifetime USRE39335E1 (en)

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US09/036,588 US6334867B1 (en) 1995-09-08 1998-03-06 Surgical graft/stent system
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050027349A1 (en) * 2003-07-29 2005-02-03 Nancy Usiak Device and method for loading a luminal graft for endoluminal delivery

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9518400D0 (en) 1995-09-08 1995-11-08 Anson Medical Ltd A surgical graft/stent system
US6814747B2 (en) 1995-09-08 2004-11-09 Anthony Walter Anson Surgical graft/stent system
US5824054A (en) * 1997-03-18 1998-10-20 Endotex Interventional Systems, Inc. Coiled sheet graft stent and methods of making and use
US5824052A (en) * 1997-03-18 1998-10-20 Endotex Interventional Systems, Inc. Coiled sheet stent having helical articulation and methods of use
US6048360A (en) * 1997-03-18 2000-04-11 Endotex Interventional Systems, Inc. Methods of making and using coiled sheet graft for single and bifurcated lumens
US7520890B2 (en) * 1998-01-26 2009-04-21 Phillips Peter W Reinforced graft and method of deployment
US20050154446A1 (en) * 1998-01-26 2005-07-14 Peter Phillips Reinforced graft
CA2318890C (en) * 1998-01-26 2007-05-22 Anson Medical Limited Reinforced graft
DE69927035T2 (en) 1998-08-03 2006-06-08 Anson Medical Ltd, Abingdon DEVICES FOR REPAIRING ARTERIES
FR2788216B1 (en) * 1999-01-08 2001-03-30 Balt Extrusion DEVICE FOR SEALING AN ANEVRISM OR THE LIKE IN A BLOOD VESSEL LIKE AN ARTERY
GB2359024A (en) * 2000-02-09 2001-08-15 Anson Medical Ltd Fixator for arteries
US6953560B1 (en) * 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
AU4327002A (en) 2000-10-25 2002-06-24 Sdgi Holdings Inc Vertically expanding intervertebral body fusion device
US6613089B1 (en) * 2000-10-25 2003-09-02 Sdgi Holdings, Inc. Laterally expanding intervertebral fusion device
US6428566B1 (en) * 2000-10-31 2002-08-06 Advanced Cardiovascular Systems, Inc. Flexible hoop and link sheath for a stent delivery system
US8870946B1 (en) * 2000-12-11 2014-10-28 W.L. Gore & Associates, Inc. Method of deploying a bifurcated side-access intravascular stent graft
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US9937066B2 (en) * 2001-04-11 2018-04-10 Andre Kerr Stent/graft assembly
US20170224469A1 (en) 2001-04-11 2017-08-10 Andrew Kerr Stent/graft assembly
GB0110670D0 (en) * 2001-05-01 2001-06-20 Anson Medical Ltd Machine for manufacturing graft-stents
US6753071B1 (en) * 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
US6949121B1 (en) 2002-02-07 2005-09-27 Sentient Engineering & Technology, Llc Apparatus and methods for conduits and materials
US9539121B2 (en) * 2002-02-07 2017-01-10 Dsm Ip Assets B.V. Apparatus and methods for conduits and materials
US7101393B2 (en) * 2002-07-22 2006-09-05 Sarac Timur P Percutaneous endovascular apparatus for repair of aneurysms and arterial blockages
US11890181B2 (en) * 2002-07-22 2024-02-06 Tmt Systems, Inc. Percutaneous endovascular apparatus for repair of aneurysms and arterial blockages
GB0220340D0 (en) * 2002-09-02 2002-10-09 Anson Medical Ltd Flexible stent-graft
GB0229274D0 (en) * 2002-12-16 2003-01-22 Anson Medical Ltd Instrument for testing pulsatile endurance of vascular implants
CA2518890C (en) 2003-04-03 2012-06-05 William A. Cook Australia Pty. Ltd. Branch stent graft deployment and method
US7413573B2 (en) 2003-10-10 2008-08-19 William A. Cook Australia Pty. Ltd. Fenestrated stent grafts
GB0402796D0 (en) * 2004-02-09 2004-03-10 Anson Medical Ltd An endoluminal surgical delivery system
US7799041B2 (en) * 2004-03-23 2010-09-21 Correx, Inc. Apparatus and method for forming a hole in a hollow organ
WO2005094525A2 (en) * 2004-03-23 2005-10-13 Correx, Inc. Apparatus and method for connecting a conduit to a hollow organ
EP1791498B1 (en) * 2004-09-22 2018-02-28 Cook Medical Technologies, LLC Stent graft with integral side arm
US20060149366A1 (en) * 2004-12-31 2006-07-06 Jamie Henderson Sintered structures for vascular graft
US7806922B2 (en) * 2004-12-31 2010-10-05 Boston Scientific Scimed, Inc. Sintered ring supported vascular graft
US7857843B2 (en) * 2004-12-31 2010-12-28 Boston Scientific Scimed, Inc. Differentially expanded vascular graft
US7306623B2 (en) * 2005-01-13 2007-12-11 Medtronic Vascular, Inc. Branch vessel graft design and deployment method
JP4887361B2 (en) * 2005-07-07 2012-02-29 メッド・インスティテュート・インコーポレイテッド Branch vessel stent graft
US7731741B2 (en) * 2005-09-08 2010-06-08 Boston Scientific Scimed, Inc. Inflatable bifurcation stent
US9375215B2 (en) 2006-01-20 2016-06-28 W. L. Gore & Associates, Inc. Device for rapid repair of body conduits
US8025693B2 (en) * 2006-03-01 2011-09-27 Boston Scientific Scimed, Inc. Stent-graft having flexible geometries and methods of producing the same
GB0617219D0 (en) * 2006-08-31 2006-10-11 Barts & London Nhs Trust Blood vessel prosthesis and delivery apparatus
GB0803302D0 (en) * 2008-02-22 2008-04-02 Barts & London Nhs Trust Blood vessel prosthesis and delivery apparatus
WO2009105699A1 (en) 2008-02-22 2009-08-27 Endologix, Inc. Design and method of placement of a graft or graft system
US20100122698A1 (en) * 2008-11-19 2010-05-20 The Nemours Foundation Neonatal airway stent
US20110054586A1 (en) * 2009-04-28 2011-03-03 Endologix, Inc. Apparatus and method of placement of a graft or graft system
US10111767B2 (en) 2010-10-29 2018-10-30 Abbott Cardiovascular Systems Inc. Sheaths used in polymer scaffold delivery systems
EP2635241B1 (en) 2010-11-02 2019-02-20 Endologix, Inc. Apparatus for placement of a graft or graft system
US8414528B2 (en) 2011-05-27 2013-04-09 Abbott Cardiovascular Systems Inc. Polymer scaffold sheaths
US8852257B2 (en) 2011-06-21 2014-10-07 Abbott Cardiovascular Systems Inc. Sheaths used with polymer scaffold
US10213329B2 (en) 2011-08-12 2019-02-26 W. L. Gore & Associates, Inc. Evertable sheath devices, systems, and methods
US8978448B2 (en) * 2011-10-11 2015-03-17 Trivascular, Inc. In vitro testing of endovascular device
US9308107B2 (en) 2012-08-27 2016-04-12 Cook Medical Technologies Llc Endoluminal prosthesis and delivery device
US9072590B2 (en) 2012-12-07 2015-07-07 Abbott Cardiovascular Systems Inc. Sheaths reducing recoil and loss of retention for polymer scaffolds crimped to balloons
US9763819B1 (en) 2013-03-05 2017-09-19 W. L. Gore & Associates, Inc. Tapered sleeve
US9788983B2 (en) 2013-06-21 2017-10-17 Abbott Cardiovascular Systems Inc. Removable sheath assembly for a polymer scaffold
US9675483B2 (en) 2013-06-21 2017-06-13 Abbott Cardiovascular Systems Inc. Protective sheath assembly for a polymer scaffold
US10098771B2 (en) 2013-09-25 2018-10-16 Abbott Cardiovascular Systems Inc. Clip sheath for a polymer scaffold
CN104586537B (en) * 2013-10-31 2017-05-10 微创心脉医疗科技(上海)有限公司 Covered stent
US9907641B2 (en) 2014-01-10 2018-03-06 W. L. Gore & Associates, Inc. Implantable intraluminal device
US9913958B2 (en) 2014-02-28 2018-03-13 Abbott Cardiovascular Systems Inc. Protective sheaths for medical devices
US10966850B2 (en) 2014-03-06 2021-04-06 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
US9364361B2 (en) 2014-03-13 2016-06-14 Abbott Cardiovascular Systems Inc. Striped sheaths for medical devices
US10959826B2 (en) 2014-10-16 2021-03-30 Cook Medical Technology LLC Support structure for scalloped grafts
US11129737B2 (en) 2015-06-30 2021-09-28 Endologix Llc Locking assembly for coupling guidewire to delivery system
US10512533B1 (en) 2016-02-23 2019-12-24 W. L. Gore & Associates, Inc. Branched graft assembly method in vivo
EP3694450B1 (en) 2017-10-11 2023-08-02 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
EP3801310A1 (en) 2018-06-11 2021-04-14 Boston Scientific Scimed Inc. Sphincterotomes and methods for using sphincterotomes

Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0326426A2 (en) * 1988-01-28 1989-08-02 JMS Co., Ltd. Plastic molded articles with shape memory property
EP0461791A1 (en) * 1990-06-11 1991-12-18 Hector D. Barone Aortic graft and apparatus for repairing an abdominal aortic aneurysm
US5167614A (en) * 1991-10-29 1992-12-01 Medical Engineering Corporation Prostatic stent
EP0621017A1 (en) * 1993-04-23 1994-10-26 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5653743A (en) * 1994-09-09 1997-08-05 Martin; Eric C. Hypogastric artery bifurcation graft and method of implantation
US5700285A (en) * 1993-08-18 1997-12-23 W. L. Gore & Associates, Inc. Intraluminal stent graft
US5709713A (en) * 1995-03-31 1998-01-20 Cardiovascular Concepts, Inc. Radially expansible vascular prosthesis having reversible and other locking structures
US5755770A (en) * 1995-01-31 1998-05-26 Boston Scientific Corporatiion Endovascular aortic graft
US5782904A (en) * 1993-09-30 1998-07-21 Endogad Research Pty Limited Intraluminal graft
US5824040A (en) * 1995-12-01 1998-10-20 Medtronic, Inc. Endoluminal prostheses and therapies for highly variable body lumens
US5833707A (en) * 1995-07-05 1998-11-10 Advanced Cardiovascular Systems, Inc. Removable stent and method of deployment
US5948018A (en) * 1993-10-21 1999-09-07 Corvita Corporation Expandable supportive endoluminal grafts
US6071308A (en) * 1997-10-01 2000-06-06 Boston Scientific Corporation Flexible metal wire stent
US6143022A (en) * 1998-08-24 2000-11-07 Medtronic Ave, Inc. Stent-graft assembly with dual configuration graft component and method of manufacture
US6187033B1 (en) * 1997-09-04 2001-02-13 Meadox Medicals, Inc. Aortic arch prosthetic graft
US6334867B1 (en) 1995-09-08 2002-01-01 Anson Medical Ltd Surgical graft/stent system
US6348065B1 (en) * 1995-03-01 2002-02-19 Scimed Life Systems, Inc. Longitudinally flexible expandable stent
US6419693B1 (en) * 1994-07-25 2002-07-16 Advanced Cardiovascular Systems, Inc. High strength member for intracorporeal use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2694688B1 (en) * 1992-08-11 1994-11-10 Novadis Sarl Expandable tubular prosthesis.

Patent Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0326426A2 (en) * 1988-01-28 1989-08-02 JMS Co., Ltd. Plastic molded articles with shape memory property
EP0461791A1 (en) * 1990-06-11 1991-12-18 Hector D. Barone Aortic graft and apparatus for repairing an abdominal aortic aneurysm
US5167614A (en) * 1991-10-29 1992-12-01 Medical Engineering Corporation Prostatic stent
EP0621017A1 (en) * 1993-04-23 1994-10-26 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5700285A (en) * 1993-08-18 1997-12-23 W. L. Gore & Associates, Inc. Intraluminal stent graft
US5782904A (en) * 1993-09-30 1998-07-21 Endogad Research Pty Limited Intraluminal graft
US5948018A (en) * 1993-10-21 1999-09-07 Corvita Corporation Expandable supportive endoluminal grafts
US6419693B1 (en) * 1994-07-25 2002-07-16 Advanced Cardiovascular Systems, Inc. High strength member for intracorporeal use
US5653743A (en) * 1994-09-09 1997-08-05 Martin; Eric C. Hypogastric artery bifurcation graft and method of implantation
US5755770A (en) * 1995-01-31 1998-05-26 Boston Scientific Corporatiion Endovascular aortic graft
US6348065B1 (en) * 1995-03-01 2002-02-19 Scimed Life Systems, Inc. Longitudinally flexible expandable stent
US5709713A (en) * 1995-03-31 1998-01-20 Cardiovascular Concepts, Inc. Radially expansible vascular prosthesis having reversible and other locking structures
US5833707A (en) * 1995-07-05 1998-11-10 Advanced Cardiovascular Systems, Inc. Removable stent and method of deployment
US6334867B1 (en) 1995-09-08 2002-01-01 Anson Medical Ltd Surgical graft/stent system
US5824040A (en) * 1995-12-01 1998-10-20 Medtronic, Inc. Endoluminal prostheses and therapies for highly variable body lumens
US6187033B1 (en) * 1997-09-04 2001-02-13 Meadox Medicals, Inc. Aortic arch prosthetic graft
US6071308A (en) * 1997-10-01 2000-06-06 Boston Scientific Corporation Flexible metal wire stent
US6143022A (en) * 1998-08-24 2000-11-07 Medtronic Ave, Inc. Stent-graft assembly with dual configuration graft component and method of manufacture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050027349A1 (en) * 2003-07-29 2005-02-03 Nancy Usiak Device and method for loading a luminal graft for endoluminal delivery
US8157850B2 (en) * 2003-07-29 2012-04-17 Boston Scientific Scimed, Inc. Device and method for loading a luminal graft for endoluminal delivery

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ES2142086T3 (en) 2000-04-01
EP0859576A1 (en) 1998-08-26
AU714124B2 (en) 1999-12-16
DE69606194T2 (en) 2001-07-19
EP0859576B1 (en) 2000-01-12
DE69606194D1 (en) 2000-02-17
AU6885996A (en) 1997-03-27
GB9518400D0 (en) 1995-11-08
US6334867B1 (en) 2002-01-01
JPH11512013A (en) 1999-10-19

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