USRE32056E - Method of forming a connection between two sealed conduits using radiant energy - Google Patents

Method of forming a connection between two sealed conduits using radiant energy Download PDF

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Publication number
USRE32056E
USRE32056E US06/271,907 US27190781A USRE32056E US RE32056 E USRE32056 E US RE32056E US 27190781 A US27190781 A US 27190781A US RE32056 E USRE32056 E US RE32056E
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United States
Prior art keywords
iadd
iaddend
wall
opaque
meltable
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US06/271,907
Inventor
Daniel B. Granzow
Garry L. Carter
David W. Ammann
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Baxter International Inc
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Baxter Travenol Laboratories Inc
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Priority claimed from US05/843,608 external-priority patent/US4157723A/en
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Priority to US06/271,907 priority Critical patent/USRE32056E/en
Application granted granted Critical
Publication of USRE32056E publication Critical patent/USRE32056E/en
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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L37/00—Couplings of the quick-acting type
    • F16L37/26—Couplings of the quick-acting type in which the connection is made by transversely moving the parts together, with or without their subsequent rotation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/14—Tube connectors; Tube couplings for connecting tubes having sealed ends
    • A61M39/143—Tube connectors; Tube couplings for connecting tubes having sealed ends both tube ends being sealed by meltable membranes pierced after connection by use of heat, e.g. using radiant energy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1429—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface
    • B29C65/1445—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface heating both sides of the joint
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1429—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface
    • B29C65/1464—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface making use of several radiators
    • B29C65/1467—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface making use of several radiators at the same time, i.e. simultaneous welding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1477—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation making use of an absorber or impact modifier
    • B29C65/148—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation making use of an absorber or impact modifier placed at the interface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/56—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using mechanical means or mechanical connections, e.g. form-fits
    • B29C65/58—Snap connection
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/72—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by combined operations or combined techniques, e.g. welding and stitching
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/74—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area
    • B29C65/747—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using other than mechanical means
    • B29C65/7473—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using other than mechanical means using radiation, e.g. laser, for simultaneously welding and severing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112—Single lapped joints
    • B29C66/1122—Single lap to lap joints, i.e. overlap joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/52—Joining tubular articles, bars or profiled elements
    • B29C66/522—Joining tubular articles
    • B29C66/5223—Joining tubular articles for forming corner connections or elbows, e.g. for making V-shaped pieces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/73—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/739—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/7392—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic
    • B29C66/73921—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic characterised by the materials of both parts being thermoplastics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/80—General aspects of machine operations or constructions and parts thereof
    • B29C66/84—Specific machine types or machines suitable for specific applications
    • B29C66/857—Medical tube welding machines
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L29/00—Joints with fluid cut-off means
    • F16L29/005—Joints with fluid cut-off means joints with cut-off devices which can be perforated
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L37/00—Couplings of the quick-acting type
    • F16L37/08—Couplings of the quick-acting type in which the connection between abutting or axially overlapping ends is maintained by locking members
    • F16L37/084—Couplings of the quick-acting type in which the connection between abutting or axially overlapping ends is maintained by locking members combined with automatic locking
    • F16L37/098—Couplings of the quick-acting type in which the connection between abutting or axially overlapping ends is maintained by locking members combined with automatic locking by means of flexible hooks
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L37/00—Couplings of the quick-acting type
    • F16L37/28—Couplings of the quick-acting type with fluid cut-off means
    • F16L37/30—Couplings of the quick-acting type with fluid cut-off means with fluid cut-off means in each of two pipe-end fittings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1027—Quick-acting type connectors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/0822—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using IR radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1403—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the type of electromagnetic or particle radiation
    • B29C65/1412—Infrared [IR] radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2027/00—Use of polyvinylhalogenides or derivatives thereof as moulding material
    • B29K2027/06—PVC, i.e. polyvinylchloride
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2069/00—Use of PC, i.e. polycarbonates or derivatives thereof, as moulding material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2071/00—Use of polyethers, e.g. PEEK, i.e. polyether-etherketone or PEK, i.e. polyetherketone or derivatives thereof, as moulding material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/06—Condition, form or state of moulded material or of the material to be shaped containing reinforcements, fillers or inserts
    • B29K2105/16—Fillers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7148—Blood bags, medical bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7542—Catheters
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L2201/00—Special arrangements for pipe couplings
    • F16L2201/40—Special arrangements for pipe couplings for special environments
    • F16L2201/44—Special arrangements for pipe couplings for special environments sterile

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A connection may be formed between sealed conduits in which each conduit carries an opaque, thermoplastic wall portion preferably having a melting range above essentially 200° C., preferably with the opaque thermoplastic wall portions being carried on the conduit about their periphery by transparent wall portions of the conduit. The opaque wall portions of the conduits are brought together into facing contact, and then exposed to sufficient .Iadd.electromagnetic .Iaddend.radiant energy to cause the opaque wall portions to fuse together, and to open an aperture through the fused wall portions. This provides sealed communication between the interiors of the conduits.

Description

BACKGROUND OF THE INVENTION
The need to form a sterile, sealed connection between a pair of conduits arises particularly in the field of blood and blood component handling, as well as in other areas where a sterile connection between containers is desired.
In the blood handling field, it may be desired to make use of only one half of a unit of blood in a bag or the like. When this happens, it is customary to discard the nonused portion of the blood unit within a day after the access to the bag was made, even when efforts are made to maintain sterility by using conventionally accepted aseptic methods of access to the blood bag. This is so because only one or two air-borne bacteria could multiply in the stored blood to create the danger of septicemia, if the bacteria were allowed to multiply over a period of more than a very few hours, and the blood was then administered to a patient.
Accordingly, to eliminate the need for disposing of the remainder of a unit of blood when only a partial unit is needed, or for the many other reasons why sealed, sterile access between various containers would be desired, a considerable amount of research has taken place in developing aseptic fluid transfer systems. For example, Berkman, et al. U.S. Pat. No. 4,022,256, discloses a sterile connection means in which a heat-fusable tube carries an inner layer of plastic material which is nonmeltable at the temperature used. An allegedly-sterile connection is made by the use of a heating die pressing the nonmeltable layer through the melting outer layers of the tube, to provide a sterile connection between the two tubes, with the melted layers of the tube forming a single, perforated layer.
The invention of the Berkman patent requires a special heating die to press the nonmelting layer of material through the meltable layers of the conduits. Also, in the embodiment shown in the Berkman patent, the meltable material presses against the heating die. Any adhesion of the meltable material to the heating die when the die is pulled apart after the pressing step could cause the connection to rip open, or at least be seriously weakened.
In accordance with this invention, the use of a heating and pressing die for obtaining a sterile connection between two conduits is eliminated. Instead, .Iadd.electromagnetic .Iaddend.radiant energy is used to selectively melt a portion of the conduit wall without providing any physical contact of a die or the like to the melting portion. Also, in this invention, mechanical connection means may be provided between the two conduits to protect the fused, sterile connection area from being mechanically ripped apart.
DESCRIPTION OF THE INVENTION
In accordance with this invention, a connection, and particularly a sterile connection, may be formed between sealed conduits. Each conduit carries a thermoplastic wall portion preferably having a melting temperature of at least essentially 200° C., and which is opaque to the particular radiant energy intended for use herein. Such melting temperature, which may be a range of temperatures, may be determined, for example, by differential thermal analysis.
To make the sterile connection, the opaque wall portions of the conduits are brought together into facing contact. The opaque wall portions are exposed to sufficient .Iadd.electromagnetic .Iaddend.radiant energy to cause them to fuse together, and to open an aperture through the fused wall portions. This provides sealed communication between the interiors of the conduits.
Preferably, the opaque thermoplastic wall portions are carried about their peripheries by a transparent, rigid housing which typically defines the end of a conduit. The remainder of the conduit may be flexible, if desired. The rigid housing is transparent, and is made of a material which is not materially softened under the specific .Iadd.electromagnetic .Iaddend.radiant energy conditions used in the process. Instead, the .Iadd.electromagnetic .Iaddend.radiant energy can pass through the transparent housing, which preferably surrounds and protects the opaque wall portions as they are placed together in facing contact, so that primarily it is the opaque facing wall portions that are heated to their melting point rather than the transparent housing, which supports and protects the opaque wall portions.
As the opaque wall portions melt, they preferably fuse together into a single sealed mass, and, due to the melting, a central aperture is formed in the melted, opaque, thermoplastic wall portion. Any bacteria residing upon the exterior surfaces of the opaque wall portions are entrapped in the melted mass and preferably killed by exposure to the melting temperature of the opaque wall portions, which melting temperature is preferably on the order of 220° to 250° C.
The .Iadd.electromagnetic .Iaddend.radiant energy can be provided to the system by means of visible, infrared, ultraviolet, or radio frequency energy as may be desired. The term "opaque" implies that the opaque wall portions are adapted to absorb a high percentage of the particular .Iadd.electromagnetic .Iaddend.radiant energy to which it is exposed. The term "transparent" implies that a lower percentage of the .Iadd.electromagnetic .Iaddend.radiant energy applied is absorbed. Focused, infrared radiant energy is particularly desirable for use.
Lasers may also be used as desired to provide the .Iadd.electromagnetic .Iaddend.radiant energy.
The opaque wall portions may be prestressed by uniaxial or biaxial orientation, or with radial stress patterns, to facilitate the formation of the central aperture as the opaque wall portions seal together. Also, unstressed wall portions may be used, with the central aperture formation taking place by cohesion.
Referring to the drawings, FIG. 1 is an elevational view of a pair of conduit ends, the other ends of which may be connected to a pair of blood bags or the like, each terminating in a pair of housings which carry an opaque, thermoplastic wall portion in accordance with this invention.
FIG. 2 is an enlarged view, taken partly in longitudinal section, of one of the conduit ends as shown in FIG. 1.
FIG. 3 is an elevational view showing the two conduit ends of FIG. 1 after they have been joined together to bring the opaque wall portions into facing contact, further showing schematically the step of exposing the opaque wall portions to sufficient .Iadd.electromagnetic .Iaddend.radiant energy to cause them to fuse together and open an aperture.
FIG. 4 is an enlarged view, taken in longitudinal section, of the structure of FIG. 3 prior to the step of exposure to .Iadd.electromagnetic .Iaddend.radiant energy as described above.
FIG. 5 is an enlarged, longitudinal sectional view of a portion of the structure of FIG. 3, taken after the step of exposure to .Iadd.electromagnetic .Iaddend.radiant energy.
Referring to the drawings, conduits 10,12, are shown to include flexible sections 14, 16, one end of each which may be connected to a conventional blood bag 17, 19 or other container.
Housings 18, 20 are shown being made of a transparent, high melting plastic material such as Lexan, a polycarbonate material sold by General Electric. Each housing defines a hollow interior chamber 21 in communication with the bore of tubes 14 or 16, plus a bayonet member 22 and a slot 24. Both bayonet 22 and slot 24 are positioned asymmetrically on the housing so that each bayonet 22 can fit into a corresponding slot 24 of an identical housing in a generally permanent, snap-fit relation. Each bayonet 22 may be retained in slot 24 by the hooking action of barbs 26.
Accordingly, upon connection of a pair of housings 18, 20, they are only disconnected again with a great deal of effort. Preferably, enlarged portions 28 of each bayonet 22 are proportioned to bear against the inner wall of the slot 24 of the mating housing, to make the disconnection of the housings yet more difficult by reducing the capability of bayonets 22 to flex rearwardly.
Each housing 18, 20 carries an opaque wall portion 30, which may be made out of a thermoplastic material having a melting temperature of preferably at least 200° C.
For example, polycarbonate materials such as Lexan may be used, or polysulfone material such as Union Carbide's Udel or Radel. Also, polyethersulfone materials may be used.
The thermoplastic opaque wall portion 30 generally contains a filler such as carbon black to render it opaque, although other desired fillers which are absorbent of the type of .Iadd.electromagnetic .Iaddend.radiant energy to be used may be provided as a substitute for carbon black, for example, iron oxide, manganese dioxide, or the like.
Opaque, thermoplastic wall portion 30 is shown to be a disc which is preferably thinner at its central portion 32 than at its peripheral portions. Disc 30 may be retained by ultrasonic sealing or the like about its periphery to its housing in a recess 34 thereof, and is shown to bulge slightly outwardly, to facilitate good, pressurized contact between facing pairs of opaque wall portions, as shown in FIG. 4. Annular groove 33 provides room for the plastic of wall portion to flow as the opaque disc is assembled into the transparent housing.
FIG. 4 also shows how bayonets 22 fit into the opposed slots 24 of the mating housings, to provide permanent connection between the respective housings, with the opaque wall portions 30 being pressed togehter, and surrounded in protective manner by the respective housings.
After housings 18, 20 have been connected, they are irradiated with .Iadd.electromagnetic .Iaddend.radiant energy of a type which is absorbed by the particular opaque wall portions used. Specifically, infrared radiations is one preferred form of .Iadd.electromagnetic .Iaddend.radiant energy. It may be provided, for example, by the use of two 150 Watt Sylvania lamps .Iadd.35 .Iaddend.with elliptical reflector type (model DJL). This provides focused, infrared light which can be focused at the centers of abutting wall portions 30 to rapidly heat them over a period of preferably ten to twenty seconds to essentially the melting point, resulting in the fusing of the respective wall portions 30 together, and the formation of aperture 36, by relief of stress or by simple cohesive forces, through wall portions 30.
Bacteria trapped on the wall portion are killed by heating of wall portion 30 to its melting temperature, and are further entrapped upon rehardening of the melted material of wall portions 30. This results in the formation of a connection between the sterile flow channels 21, while the continued maintenance of sterility in the channels is assured.
The fused wall portions 30 fuse together to form a hermetic seal about aperture 36, to prevent a break in the sterility of the flow path. At the same time, the seal line 38 between the respective membrane wall portions 30 is protected from mechanical rupture by the generally permanent connection between respective housings 18, 20.
Alternatively, if it is desired to utilize radio frequency eneregy or the like as the .Iadd.electromagnetic .Iaddend.radiant energy, opaque wall portions 30 may be made out of a plasticized polyvinylchloride, while the remainder of housings 18, 20 may be made of a plastic material which is relatively inert to R.F. energy, for example polypropylene, polyethylene, or a similar material which does not heat significantly when it is exposed to radio frequency or other high energy, high frequency radiant electrical fields.
Accordingly, by this invention a sterile connection can be made, for example, between a full and an empty blood bag by simply connecting a conduit from each of the bags which carries a respective housing 18, 20 in accordance with this invention. The connected housings can be briefly exposed, for example for about fifteen seconds to focused infrared radiation, to melt the opaque wall sections, fusing them together and forming an aperture through the sections. The sterile connection is thus achieved, through which a portion of the blood of the full blood bag can be passed to the empty bag for use. Thereafter, the bags may be disconnected in conventional manner by heat sealing one or both of the flexible conduits 14, 16 leading from the blood bag to the housings 18, .[.29.]. .Iadd.20 .Iaddend.in a HEMATRON® heat sealer, sold by the Fenwal Division of Baxter Travenol Laboratories, Inc. Then the blood bags may be conveyed to their desired site of use, or back to long-term storage.
The above has been offered for illustrative purposes only, and is not intended to limit the scope of the invention of this application, which is as defined in the claims below.

Claims (36)

That which is claimed is:
1. The method of forming a connection between sealed conduits, each conduit carrying an opaque, thermoplastic wall portion, which method comprises:
bringing said opaque wall portions of said conduits together into facing contact, and .[.exposing said opaque wall portions to sufficient.]. .Iadd.applying sufficient electromagnetic .Iaddend.radiant energy to cause said opaque wall portions to fuse together and to open an aperture through said fused wall portions, providing sealed communication between the interiors of said conduits.
2. The method of claim 1 in which said opaque, thermoplastic wall portions are carried about their peripheries on said conduits by transparent, rigid housing portions of said conduits.
3. The method of claim 2 in which the interiors of said conduits are sterile.
4. The method of claim 3 in which the melting temperature of said thermoplastic wall portion is at least 200 degrees C.
5. The method of claim 4 in which said housing portion defines means for generally permanent connection with an identical housing portion in a position to bring the respective opaque wall portions of said housing portions together into facing contact, to protect the fused, opaque wall portions from mechanical stress.
6. The method of claim 5 in which said .Iadd.electromagnetic .Iaddend.radiant energy is infrared radiation.
7. The method of claim 6 in which .[.the opaque, thermoplastic wall portions are exposed to.]. said infrared radiation .Iadd.is applied .Iaddend.for ten to twenty seconds.
8. A connector member for providing sealed sterile connection between containers, which connector member comprises a hollow, transparent housing adapted for connection to a first container, the hollow interior of said housing member being sealed from the exterior by housing walls, some of said housing wall comprising an opaque wall portion separating the hollow housing interior from the exterior, said opaque wall portion being sealed to the remainder of the transparent housing, said opaque wall portion being made of a thermoplastic material, and means for connecting said housing to a corresponding second, hollow, transparent, sealed housing which carries, as a part of .[.a.]. .Iadd.the .Iaddend.second housing.[.,.]. walls separating the second housing interior from the exterior, .Iadd.a .Iaddend.second opaque wall portion, said connection between the respective housings being adapted to bring the respective opaque wall portions together into facing contact, said opaque wall portions being adapted to facilitate the opening of an aperture upon heating said wall portions to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy.
9. The sterile connection member of claim 8 in which said transparent housing defines an asymmetrically positioned bayonet member and an asymmetrically positioned slot member, said bayonet member being adapted to pass into a corresponding slot member of said second housing and said slot member being proportioned to receive a corresponding bayonet member from said second housing, to provide generally permanent connection between said housings.
10. The connector member of claim 9 in which said bayonet member carries a barb on one side thereof, and a reinforcement member is provided to restrict the movement of said bayonet member in the direction away from said one side.
11. The connector member of claim 10 in which said opaque, thermoplastic wall portion is made of material having a melting temperature of at least 200 degress C.
12. The connector member of claim 11 in which said transparent housing is in sealing communication with the end of flexible tubing for connection to a medical liquid container.
13. A blood bag which carries the connector member of claim 12.
14. A connector member which comprises first and second hollow, transparent, generally rigid housings connected in sealed, communicating relation with the ends of hollow, flexible tubing, the walls of said housings sealing the hollow interiors thereof from the exterior except through said flexible tube, a portion of each of the housing member walls comprising .Iadd.an .Iaddend.opaque wall .[.portions.]. .Iadd.portion .Iaddend.sealed to the remainder of said transparent .[.housings.]. and in abutting contact with each other, said opaque wall .[.portions.]. .Iadd.portionof said first housing .Iaddend.being adapted to be brought into abutting relation with .[.an.]. .Iadd.said .Iaddend.opaque wall portion of .[.a similar connector member.]. .Iadd.said second housing .Iaddend.and adapted to facilitate the opening of an aperture through said abutting opaque wall portions upon heating said wall portions to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy.
15. The connector member of claim 14 in which said opaque thermoplastic wall portions are made of a material having a melting temperature of at least 200 degrees C.
16. The connector member of claim 15 in which each transparent housing defines an asymmetrically positioned bayonet member and an asymmetrically positioned slot member, each bayonet member passing through the corresponding slot member of the other housing in retaining relationship thereto, to provide generally permanent connection between said housings.
17. The connector member of claim 16 in which each bayonet carries a barb on one side thereof, and a reinforcement member is provided to restrict the movement of said bayonet member in the direction away from said one side.
18. The connector member of claim 17 in which said opaque wall portions are stressed to facilitate the opening of an aperture through said wall portions upon heating said opaque wall portions to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy.
19. The connector member of claim 8 in which said opaque wall portions are stressed to facilitate the opening of an aperture through said wall portions upon heating said opaque wall portions to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy.
20. The method of opening a connection between sealed conduits within a transparent housing, said conduits being separated by opaque wall means positioned within said housing, comprising .[.exposing said opaque wall means to a source of.]. .Iadd.applying electromagnetic .Iaddend.radiant energy .Iadd.from a source .Iaddend.positioned outside of said transparent housing of an intensity and duration sufficient to cause said opaque wall means to fuse and to open an aperture therethrough, providing communication between the interiors of said sealed conduits.
21. The method of forming a connection between sealed conduits in which each conduit is positioned within a separate, generally transparent housing which carries an opaque wall portion separing the interior of said housing from the exterior, which method comprises:
bringing the opaque wall portions of the housing into facing contact, in which the facing opaque wall portions are surrounded by the respective housings, and .[.exposing said opaque wall portions to sufficient.]. .Iadd.applying sufficient electromagnetic .Iaddend.radiant energy to cause said opaque wall portions to fuse together and to open an aperture through said fused wall portions, providing sealed communication between said conduits.
22. The method of claim 21 in which said opaque wall portions are made of a thermoplastic material, and are attached about their peripheries to said transparent housings, the .Iadd.electromagnetic .Iaddend.radiant energy being adapted to pass through said transparent housings to said opaque wall portions.
23. The method of claim 22 in which the melting range of said thermoplastic wall portions includes a temperature of at least 200° C.
24. The method of claim 23 in which each generally transparent housing defines means for generally permanent connection with an identical housing in a position to bring the respective opaque wall portions of said housings together into said facing contact, to protect the fused opaque wall portions from a mechanical stress.
25. The method of claim 24 in which said .Iadd.electromagnetic .Iaddend.radiant energy is infrared radiation.
26. A connector member for providing sealed connection between a pair of conduits which comprises transparent housing means enclosing a portion of said pair of conduits, and opaque wall means positioned within said housing means in communication with and to separate the respective conduits, said opaque wall means being adapted to facilitate the opening of an aperture upon heating said opaque wall means to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy.
27. A connector member for providing sealed, sterile connection, said connector member comprising a pair of hollow, transparent housings, the hollow interiors of each of said housings being sealable from the exterior, some of the walls of each housing comprising an opaque wall portion separating the hollow housing interior from the exterior, said opaque wall portions being sealed to the remainder of said transparent housing, and means for connecting said housings together, said connection between the respective housings being adapted to bring the respective opaque wall portions together into facing contact, the opaque wall portions being adapted to facilitate the opening of an aperture upon heating said opaque wall portions to the melting temperature by .[.means.]. .Iadd.the application .Iaddend.of .Iadd.electromagnetic .Iaddend.radiant energy to fuse said opaque wall portions together to provide a connection between the interiors of the respective housings.
28. The connector member of claim 8 in which said thermoplastic material from which the opaque wall portions is made is a filled organic plastic formulation. .Iadd.
29. A member comprising body means attachable to the end portion of a conduit, said body means being made of a material which is generally transparent to the passage of electromagnetic radiant energy, and means defining a meltable wall sealingly disposed on said body means and being made of a material which is generally opaque to the passage of electromagnetic radiant energy for normally sealing the conduit from communication with the atmosphere and for forming, in response to the application of electromagnetic radiant energy to melt said wall, an opening in said wall. .Iaddend. .Iadd.30. A member according to claim 29
and further including means for bringing said meltable wall into facing contact with a corresponding meltable wall of a second member as defined by claim 29, and
wherein said opening in each of said meltable walls which is formed in response to said application of eletromagnetic radiant energy is disposed generally along the point of facing contact between said meltable walls. .Iaddend. .Iadd.31. A member comprising body means attachable to the end portion of a conduit and being made of a material which is generally transparent to the passage of infrared radiation, and means defining a meltable wall sealingly disposed on said body means and being made of a material which is generally opaque to the passage of infrared radiation for normally sealing the conduit from communication with the atmosphere and for forming, in response to the application of infrared radiation to
melt said wall, an opening in said wall. .Iaddend. .Iadd.32. A member according to claim 31
wherein the opaque material of said meltable wall is black in color. .Iaddend. .Iadd.33. A member according to claim 31
and further including means for bringing said meltable wall into facing contact with a corresponding meltable wall of a second member as defined in claim 32, and
wherein said opening in each of said meltable walls which is formed in response to said application of infrared radiation is disposed generally along the point of facing contact between said meltable walls. .Iaddend. .Iadd.34. A member according to claim 30 or 33
wherein said meltable wall includes at said point of facing contact a generally outwardly bowed portion to facilitate said facing contact. .Iaddend. .Iadd.35. A member according to claim 29 or 31
wherein said body means includes body wall means defining a hollow interior adapted for communication with the conduit end portion, and
wherein said meltable wall extends in said hollow interior and is operative for normally sealing said hollow interior, and thus said conduit end
portion, from communication with the atmosphere. .Iaddend. .Iadd.36. A member according to claim 35
wherein said body means includes passage means communicating with said hollow interior and adapted for attachment to the end portion of the conduit. .Iaddend. .Iadd.37. A member according to claim 35
wherein said meltable wall includes a disc-shaped member having a center portion which is thinner than its peripheral portions. .Iaddend. .Iadd.38. A member according to claim 37
wherein said meltable wall is sealed about said peripheral portions to said body wall means. .Iaddend. .Iadd.39. A member according to claim 29 or 31 wherein said meltable wall is made of material having a melting temperature of at least 200°C. .Iaddend. .Iadd.40. A member according to claim 39 wherein said meltable wall is made of thermoplastic
material. .Iaddend. .Iadd.41. A member comprising body means being made of a material which is generally transparent to the passage of electromagnetic radiant energy and which defines a fluid passage attachable to a conduit for normally sealing the conduit from communication with the atmosphere and including means for forming on said body means a meltable surface made of a material which is generally opaque to the passage of electromagnetic radiant energy, said means being further operative for creating in response to the application of electromagnetic radiant energy to melt said surface, an opening in said body means through said surface. .Iaddend. .Iadd.42. A member comprising body means being made of a material which is generally transparent to the passage of infrared radiation and defining a fluid passage attachable to a conduit for normally sealing the conduit from communication with the atmosphere and including means for forming on said body means a meltable surface being made of a material which is generally opaque to the passage of infrared radiation, said means being further operative for creating in response to the application of infrared radiation to melt said surface, an opening in said body means through said surface. .Iaddend. .Iadd.43. A member according to claim 42
wherein the material of said meltable surface is black in color. .Iaddend.
.Iadd.44. A member according to claim 41 or 42
wherein said wall means includes means for forming in said fluid passage a closed end portion, and
wherein said meltable surface is disposed generally adjacent to said closed end portion of said fluid passage. .Iaddend. .Iadd.45. An assembly for sealing and connecting the end portions of a pair of conduits, said assembly comprising
housing means having walls enclosing a hollow interior, said walls being made of a material having a first rate of absorption of electromagnetic radiant energy, said housing means further including spaced first and second passage means each communicating with said hollow interior and each adapted for communicating with a respective conduit end portion; and
meltable wall means extending across said hollow interior in the interval between said spaced first and second passage means, said meltable walls being made of a material having a second rate of absorption of electromagnetic radiant energy greater than said first rate and being operative for normally blocking flow communication between said first and second passage means through said hollow interior and for forming, in response to the application of electromagnetic radiant energy through said housing means walls to melt said meltable wall means, an opening establishing flow communication between said first and second passage
means through said hollow interior. .Iaddend. .Iadd.46. A container comprising
wall means defining an interior,
means defining a port communicating with said interior, and
conduit means communicating with said port and including body means being made of a material which is generally transparent to the passage of electromagnetic radiant energy and means defining a meltable wall sealingly disposed on said body means and being made of a material which is generally opaque to the passage of electromagnetic radiant energy for normally sealing said port, and thus said container interior, and for forming, in response to the application for electromagnetic radiant energy melt said wall, an opening in said wall. .Iaddend. .Iadd.47. A container according to claim 46
and further including means for bringing said meltable wall into facing contact with a corresponding meltable wall associated with a second container having conduit means as defined by claim 46, and
wherein said opening in each of said meltable walls which is formed in response to said application of electromagnetic radiant energy is disposed generally along the point of facing contact between said meltable walls. .Iaddend. .Iadd.48. A container comprising
wall means defining an interior,
means defining a port communicating with said interior, and
conduit means communicating with said port and including body means being made of a material which is generally transparent to the passage of infrared radiation and means defining a meltable wall sealingly disposed on said body means and being made of a material which is generally opaque to the passage of infrared radiation for normally sealing said ort, and thus said container interior, and for forming in response to the application of infrared radiation to melt said wall, an opening in said
wall. .Iaddend. .Iadd.49. A container according to claim 48
and further including means for bringing said meltable wall into facing contact with a corresponding meltable wall associated with a second container having conduit means as defined by claim 62, and
wherein said opening in each of said meltable walls which is formed in response to said application of infrared radiation is disposed generally along the point of facing contact between said meltable walls. .Iaddend. .Iadd.50. A container according to claim 47 or 49
wherein said meltable wall includes at said point of facing contact a generally outwardly bowed portion to facilitate said facing contact. .Iaddend. .Iadd.51. A container according to claim 46 or 48 wherein said meltable wall is made of material having a melting temperature of at least
200° C. .Iadd.52. A blood collection system comprising
a blood collection subassembly for collecting blood from a donor,
a blood transfer subassembly for receiving a portion of the contents of said blood collection subassembly,
connector means communicating with each of said blood collection and said blood transfer subassemblies, each of said connector means including
means defining a meltable wall made of an electromagnetic radiant energy absorbing material for normally sealing said associated subassembly from communication with the atmosphere and for forming, in response to the application of electromagnetic radiant energy to melt said wall, an opening in said wall,
means for coupling said connector means associated with said blood collection subassembly with said connector means associated with said blood transfer subsassembly with said respective meltable walls in facing contact,
said meltable walls being further operative, in response to the application of electromagnetic radiant energy when said connector means are coupled together, for jointly melting to form a common opening defining a fluid path between said blood collection and transfer subassemblies. .Iaddend. .Iadd.53. A blood collection system according to claim 52
wherein the electromagnetic radiant energy applied includes infrared radiation, and
wherein the material of said meltable wall of each said connector means is generally opaque to the passage of infrared radiation. .Iaddend. .Iadd.54. A blood collection system according to claim 52 or 53
wherein said meltable wall of each of said connector means is made of material having a melting temperature of at least 200° C. .Iaddend.
US06/271,907 1977-10-19 1981-06-09 Method of forming a connection between two sealed conduits using radiant energy Expired - Lifetime USRE32056E (en)

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641622A (en) * 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5858016A (en) * 1992-07-14 1999-01-12 Baxter International Inc. Sterile/aseptic connector
WO2000062820A2 (en) 1999-04-20 2000-10-26 Baxter International Inc. Method and apparatus for manipulating pre-sterilized components in an active sterile field
US6174404B1 (en) * 1994-10-27 2001-01-16 Supercom Ltd Laminated plastic cards and process and apparatus for making them
US20060289112A1 (en) * 2005-06-23 2006-12-28 Holman Thomas J Methods of making medical devices
US20080217915A1 (en) * 2005-03-04 2008-09-11 Nils Arthun Method and Device for Interconnecting, Sealed Against Contamination, the Ends of Elongate Elements Such as Tubes or Pipes
US20080277878A1 (en) * 2005-03-04 2008-11-13 Nils Arthun Device and Method for Contamination-Free and/or Sterile Sealing Between At Least Two Interconnectable Connecting Means
US20100133807A1 (en) * 2007-04-24 2010-06-03 Hyclone Laboratories, Inc. Sterile connector systems
US7938454B2 (en) 2007-04-24 2011-05-10 Hyclone Laboratories, Inc. Sterile connector systems
US20120204990A1 (en) * 2011-02-16 2012-08-16 Fenwal, Inc. Sterile Docking Device, Medical Fluid Flow System With Sterile Docking Device and Method Of Using Same
US9199070B2 (en) 2011-12-21 2015-12-01 Fenwal, Inc. Fluid flow conduits and apparatus and methods for making and joining fluid conduits
US20160053296A1 (en) * 2014-08-19 2016-02-25 General Electric Company Systems and methods for aseptic sampling
US9289522B2 (en) 2012-02-28 2016-03-22 Life Technologies Corporation Systems and containers for sterilizing a fluid
US9308709B2 (en) 2013-06-06 2016-04-12 Fenwal, Inc. Bonding apparatus and method
US9440396B2 (en) 2014-06-19 2016-09-13 Fenwal, Inc. Sterile connection device for making multiple connections
US9839582B2 (en) 2014-12-02 2017-12-12 Fenwal, Inc. Sterile connection syringe assemblies
CN114007850A (en) * 2019-07-01 2022-02-01 美国圣戈班性能塑料公司 Section bar connecting piece
US20220381384A1 (en) * 2021-05-27 2022-12-01 Entegris, Inc. Aseptic coupling assembly and method of aseptic coupling
US11878476B2 (en) 2020-06-19 2024-01-23 Saint-Gobain Performance Plastics Corporation Composite article and method of forming a composite article

Citations (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US998507A (en) * 1909-07-22 1911-07-18 Hasty Mfg Company Automatically-operable valve.
US1010626A (en) * 1909-07-22 1911-12-05 Hasty Mfg Company Automatically-operable valve.
US1151300A (en) * 1915-01-22 1915-08-24 Angelo L Soresi Instrument for the transfusion of blood.
US1292603A (en) * 1916-06-05 1919-01-28 Westinghouse Electric & Mfg Co Valve-sealing means.
US1313225A (en) * 1919-08-12 Coupling eoe
US1921809A (en) * 1931-11-06 1933-08-08 Crain Earl Gas pipe stop
US2507379A (en) * 1946-02-09 1950-05-09 Willard L Morrison Demountable cold box
US2553259A (en) * 1946-09-02 1951-05-15 Nordisk Insulinlab Process of joining plastic substances
US2622053A (en) * 1945-12-04 1952-12-16 Henry W Clowe Method of joining surfaces of heat-fusible materials
US2729221A (en) * 1950-09-12 1956-01-03 Gorham George Safety device for gas burning appliances
US2744432A (en) * 1954-07-27 1956-05-08 Sherman Klove Company Reversible ratchet wrench
US2782496A (en) * 1954-04-08 1957-02-26 Gen Electric Method for assembling refrigeration systems
US2839788A (en) * 1953-04-24 1958-06-24 Dembiak Matthew Method of making hollow plastic or rubber articles
GB801162A (en) * 1955-11-01 1958-09-10 Carrier Engineering Co Ltd Improvements in or relating to coupling elements and devices for fluid-flow conduits
US2903004A (en) * 1955-11-01 1959-09-08 Carrier Corp Coupling devices
US2910083A (en) * 1958-01-10 1959-10-27 C W Fuelling Inc Method and apparatus for terminating and extending fluid transmission mains
US2933333A (en) * 1955-09-26 1960-04-19 Crane Co Pipe coupling
US2958545A (en) * 1958-09-15 1960-11-01 Weatherhead Co Rupturable union device
US2998018A (en) * 1959-07-06 1961-08-29 Lockheed Aircraft Corp Electro thermal valve
US3023762A (en) * 1960-08-30 1962-03-06 Charles W Fuelling Inc Gas main terminal fixture
US3052253A (en) * 1960-05-11 1962-09-04 Pirelli Valve for liquid metal
US3084705A (en) * 1961-03-13 1963-04-09 Canrad Prec Ind Device for rupturing glass seals
US3214502A (en) * 1960-08-08 1965-10-26 Kendall & Co Method and apparatus for making adhesive tapes
US3244412A (en) * 1962-10-18 1966-04-05 Northwestern Steel & Wire Comp Apparatus for melting meltable materials
GB1027528A (en) * 1964-01-28 1966-04-27 Kugler Emanuel Improvements in the heat sealing and severing of materials
US3285627A (en) * 1964-02-10 1966-11-15 Weatherhead Co Pipe coupling
US3384526A (en) * 1965-09-02 1968-05-21 Research Inc Method and machine for joining plastics
US3391951A (en) * 1966-12-07 1968-07-09 Weatherhead Co Diaphragm sealed coupling
US3404051A (en) * 1965-03-09 1968-10-01 Morey Paper Mill Supply Co Method of splicing thermoplastic rope ends by flame treatment
US3410979A (en) * 1964-05-28 1968-11-12 Burroughs Corp Method and apparatus for drilling holes by means of a focused laser beam
US3466065A (en) * 1968-04-04 1969-09-09 Weatherhead Co Rupturable diaphragm coupling
US3493002A (en) * 1967-12-11 1970-02-03 Chrysler Corp Coupling apparatus
US3549451A (en) * 1968-03-06 1970-12-22 Emanuel Kugler Method of manufacturing satchel bottom bags
US3588440A (en) * 1969-06-26 1971-06-28 Hughes Aircraft Co Laser combination energy system
US3616024A (en) * 1969-07-14 1971-10-26 Phillips Petroleum Co Method and apparatus for welding heat sealable pipes
US3640790A (en) * 1969-05-21 1972-02-08 Canadian Ind Sealing plastic film
DE2331687A1 (en) * 1972-06-23 1974-01-10 Avon Medicals COUPLING FOR EQUIPMENT IN THE FIELD OF MEDICINE OR RESEARCH
US3812659A (en) * 1972-08-02 1974-05-28 Whirlpool Co Canister vacuum cleaner latching means
US3865411A (en) * 1973-03-29 1975-02-11 Union Carbide Corp Sterile connector for conduits
DE2452858A1 (en) * 1973-11-05 1975-05-07 Francis Tenczar STERILE CLUTCH
US3909910A (en) * 1973-03-29 1975-10-07 Union Carbide Corp Method of joining the ends of two conduits together in a sterile manner
US3913348A (en) * 1974-07-22 1975-10-21 Gen Electric Refrigerant system connecting apparatus
US3941641A (en) * 1974-02-26 1976-03-02 William C. Heller, Jr. Bonding method and apparatus
US3968195A (en) * 1974-06-17 1976-07-06 Marilyn Bishop Method for making sterile connections
US3977385A (en) * 1973-06-21 1976-08-31 National Research Development Corporation Internal combustion engines with straight line reinforcing members between cylinder heads and main bearings
US3986508A (en) * 1973-08-22 1976-10-19 Abcor, Inc. Sterilizable, medical connector for blood processing
US4004586A (en) * 1975-03-12 1977-01-25 Baxter Travenol Laboratories, Inc. Method and apparatus for sealed, sterile connection
DE2639584A1 (en) * 1975-09-25 1977-03-31 California Inst Of Techn METHOD AND DEVICE FOR GIVEN-FREE TRANSFER OF LIQUIDS BETWEEN CONTAINERS
US4019512A (en) * 1975-12-04 1977-04-26 Tenczar Francis J Adhesively activated sterile connector
US4030494A (en) * 1973-11-05 1977-06-21 Francis Tenczar Fluid connectors
US4139005A (en) * 1977-09-01 1979-02-13 Dickey Gilbert C Safety release pipe cap
US4177372A (en) * 1976-05-26 1979-12-04 Hitachi, Ltd. Method and apparatus for laser zone melting

Patent Citations (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1313225A (en) * 1919-08-12 Coupling eoe
US998507A (en) * 1909-07-22 1911-07-18 Hasty Mfg Company Automatically-operable valve.
US1010626A (en) * 1909-07-22 1911-12-05 Hasty Mfg Company Automatically-operable valve.
US1151300A (en) * 1915-01-22 1915-08-24 Angelo L Soresi Instrument for the transfusion of blood.
US1292603A (en) * 1916-06-05 1919-01-28 Westinghouse Electric & Mfg Co Valve-sealing means.
US1921809A (en) * 1931-11-06 1933-08-08 Crain Earl Gas pipe stop
US2622053A (en) * 1945-12-04 1952-12-16 Henry W Clowe Method of joining surfaces of heat-fusible materials
US2507379A (en) * 1946-02-09 1950-05-09 Willard L Morrison Demountable cold box
US2553259A (en) * 1946-09-02 1951-05-15 Nordisk Insulinlab Process of joining plastic substances
US2729221A (en) * 1950-09-12 1956-01-03 Gorham George Safety device for gas burning appliances
US2839788A (en) * 1953-04-24 1958-06-24 Dembiak Matthew Method of making hollow plastic or rubber articles
US2782496A (en) * 1954-04-08 1957-02-26 Gen Electric Method for assembling refrigeration systems
US2744432A (en) * 1954-07-27 1956-05-08 Sherman Klove Company Reversible ratchet wrench
US2933333A (en) * 1955-09-26 1960-04-19 Crane Co Pipe coupling
GB801162A (en) * 1955-11-01 1958-09-10 Carrier Engineering Co Ltd Improvements in or relating to coupling elements and devices for fluid-flow conduits
US2903004A (en) * 1955-11-01 1959-09-08 Carrier Corp Coupling devices
US2910083A (en) * 1958-01-10 1959-10-27 C W Fuelling Inc Method and apparatus for terminating and extending fluid transmission mains
US2958545A (en) * 1958-09-15 1960-11-01 Weatherhead Co Rupturable union device
US2998018A (en) * 1959-07-06 1961-08-29 Lockheed Aircraft Corp Electro thermal valve
US3052253A (en) * 1960-05-11 1962-09-04 Pirelli Valve for liquid metal
US3214502A (en) * 1960-08-08 1965-10-26 Kendall & Co Method and apparatus for making adhesive tapes
US3023762A (en) * 1960-08-30 1962-03-06 Charles W Fuelling Inc Gas main terminal fixture
US3084705A (en) * 1961-03-13 1963-04-09 Canrad Prec Ind Device for rupturing glass seals
US3244412A (en) * 1962-10-18 1966-04-05 Northwestern Steel & Wire Comp Apparatus for melting meltable materials
GB1027528A (en) * 1964-01-28 1966-04-27 Kugler Emanuel Improvements in the heat sealing and severing of materials
US3285627A (en) * 1964-02-10 1966-11-15 Weatherhead Co Pipe coupling
US3410979A (en) * 1964-05-28 1968-11-12 Burroughs Corp Method and apparatus for drilling holes by means of a focused laser beam
US3404051A (en) * 1965-03-09 1968-10-01 Morey Paper Mill Supply Co Method of splicing thermoplastic rope ends by flame treatment
US3384526A (en) * 1965-09-02 1968-05-21 Research Inc Method and machine for joining plastics
US3391951A (en) * 1966-12-07 1968-07-09 Weatherhead Co Diaphragm sealed coupling
US3493002A (en) * 1967-12-11 1970-02-03 Chrysler Corp Coupling apparatus
US3549451A (en) * 1968-03-06 1970-12-22 Emanuel Kugler Method of manufacturing satchel bottom bags
US3466065A (en) * 1968-04-04 1969-09-09 Weatherhead Co Rupturable diaphragm coupling
US3640790A (en) * 1969-05-21 1972-02-08 Canadian Ind Sealing plastic film
US3588440A (en) * 1969-06-26 1971-06-28 Hughes Aircraft Co Laser combination energy system
US3616024A (en) * 1969-07-14 1971-10-26 Phillips Petroleum Co Method and apparatus for welding heat sealable pipes
US3902489A (en) * 1972-06-23 1975-09-02 Avon Medicals Couplings
DE2331687A1 (en) * 1972-06-23 1974-01-10 Avon Medicals COUPLING FOR EQUIPMENT IN THE FIELD OF MEDICINE OR RESEARCH
GB1428391A (en) * 1972-06-23 1976-03-17 Avon Medicals Couplings
US3812659A (en) * 1972-08-02 1974-05-28 Whirlpool Co Canister vacuum cleaner latching means
US3865411A (en) * 1973-03-29 1975-02-11 Union Carbide Corp Sterile connector for conduits
US3909910A (en) * 1973-03-29 1975-10-07 Union Carbide Corp Method of joining the ends of two conduits together in a sterile manner
US3977385A (en) * 1973-06-21 1976-08-31 National Research Development Corporation Internal combustion engines with straight line reinforcing members between cylinder heads and main bearings
US3986508A (en) * 1973-08-22 1976-10-19 Abcor, Inc. Sterilizable, medical connector for blood processing
DE2452858A1 (en) * 1973-11-05 1975-05-07 Francis Tenczar STERILE CLUTCH
US4022205A (en) * 1973-11-05 1977-05-10 Tenczar Francis J Fluid connectors
US4030494A (en) * 1973-11-05 1977-06-21 Francis Tenczar Fluid connectors
US3941641A (en) * 1974-02-26 1976-03-02 William C. Heller, Jr. Bonding method and apparatus
US3968195A (en) * 1974-06-17 1976-07-06 Marilyn Bishop Method for making sterile connections
US3913348A (en) * 1974-07-22 1975-10-21 Gen Electric Refrigerant system connecting apparatus
US4004586A (en) * 1975-03-12 1977-01-25 Baxter Travenol Laboratories, Inc. Method and apparatus for sealed, sterile connection
US4022256A (en) * 1975-08-06 1977-05-10 California Institute Of Technology Aseptic fluid transfer system
DE2639584A1 (en) * 1975-09-25 1977-03-31 California Inst Of Techn METHOD AND DEVICE FOR GIVEN-FREE TRANSFER OF LIQUIDS BETWEEN CONTAINERS
US4019512A (en) * 1975-12-04 1977-04-26 Tenczar Francis J Adhesively activated sterile connector
US4177372A (en) * 1976-05-26 1979-12-04 Hitachi, Ltd. Method and apparatus for laser zone melting
US4139005A (en) * 1977-09-01 1979-02-13 Dickey Gilbert C Safety release pipe cap

Non-Patent Citations (16)

* Cited by examiner, † Cited by third party
Title
B. A. Myhre et al., "An Aseptic Fluid Transfer System for Blood and Blood Components", Transfusion, Sep.-Oct., 1978, pp. 546-553.
B. A. Myhre et al., An Aseptic Fluid Transfer System for Blood and Blood Components , Transfusion, Sep. Oct., 1978, pp. 546 553. *
DHEW Publication No. (NIH) 76 1004, Frozen Red Cell Outdating , Mar. 14, 1975, Bethesda, Maryland, pp. 43 51. *
DHEW Publication No. (NIH) 76-1004, "Frozen Red Cell Outdating", Mar. 14, 1975, Bethesda, Maryland, pp. 43-51.
F. J. Tenczar, Transfusion, Sep. Oct. 1976, pp. 477 482, entitled Sterile Connector . *
F. J. Tenczar, Transfusion, Sep.-Oct. 1976, pp. 477-482, entitled "Sterile Connector".
R. E. Trotman, "Sterilization by Radio Frequency Induction Heating: A Method for the In Situ Sterilization of Vessels in Automatic Bacteriological Apparatus", Journal of Applied Bacteriology 32, pp. 2, 9, 7-300, (1960).
R. E. Trotman, Sterilization by Radio Frequency Induction Heating: A Method for the In Situ Sterilization of Vessels in Automatic Bacteriological Apparatus , Journal of Applied Bacteriology 32, pp. 2, 9, 7 300, (1960). *
The International Dictionary of Physics, 1961, pp. 239 241. *
The International Dictionary of Physics, 1961, pp. 239-241.
Van Nostrand s Scientific Encyclopedia, 1968, pp. 582, 583, 1458 and 1459. *
Van Nostrand's Scientific Encyclopedia, 1968, pp. 582, 583, 1458 and 1459.
Webster s New Collegiate Dictionary, 1979, p. 583. *
Webster's New Collegiate Dictionary, 1979, p. 583.
William W. Cooper et al., pp. 31 41 of DHEW Publication No. (NIH 76 1004, Mar. 14, 1975, entitled, A Two Stage Heat Sterilizable Connector For Use In Processing Frozen Blood . *
William W. Cooper et al., pp. 31-41 of DHEW Publication No. (NIH 76-1004, Mar. 14, 1975, entitled, "A Two-Stage Heat Sterilizable Connector For Use In Processing Frozen Blood".

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221315B1 (en) 1990-09-13 2001-04-24 Baxter International Inc. Apparatus for separation of biologic components from heterogeneous cell populations
US6596179B2 (en) 1990-09-13 2003-07-22 Baxter International Inc. Apparatus for the separation of biologic components from heterogeneous cell populations
US5641622A (en) * 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5858016A (en) * 1992-07-14 1999-01-12 Baxter International Inc. Sterile/aseptic connector
US6174404B1 (en) * 1994-10-27 2001-01-16 Supercom Ltd Laminated plastic cards and process and apparatus for making them
US7655198B2 (en) 1999-04-20 2010-02-02 Baxter International Inc. Method and apparatus for manipulating pre-sterilized components in an active sterile field
WO2000062820A2 (en) 1999-04-20 2000-10-26 Baxter International Inc. Method and apparatus for manipulating pre-sterilized components in an active sterile field
US20050161614A1 (en) * 1999-04-20 2005-07-28 Bilstad Arnold C. Apparatus for manipulating pre-sterilized components in an active sterile field
US20060110282A1 (en) * 1999-04-20 2006-05-25 Bilstad Arnold C Method and apparatus for manipulating pre-sterilized components in an active sterile field
US7264771B2 (en) 1999-04-20 2007-09-04 Baxter International Inc. Method and apparatus for manipulating pre-sterilized components in an active sterile field
US20080277878A1 (en) * 2005-03-04 2008-11-13 Nils Arthun Device and Method for Contamination-Free and/or Sterile Sealing Between At Least Two Interconnectable Connecting Means
US20080217915A1 (en) * 2005-03-04 2008-09-11 Nils Arthun Method and Device for Interconnecting, Sealed Against Contamination, the Ends of Elongate Elements Such as Tubes or Pipes
US7922211B2 (en) 2005-03-04 2011-04-12 Millipore Ab Method and device for interconnecting, sealed against contamination, the ends of elongate elements such as tubes or pipes
US8029023B2 (en) 2005-03-04 2011-10-04 Millipore Ab Device and method for contamination-free and/or sterile sealing between at least two interconnectable connecting means
US7419563B2 (en) 2005-06-23 2008-09-02 Boston Scientific Scimed, Inc. Methods of making medical devices
US20060289112A1 (en) * 2005-06-23 2006-12-28 Holman Thomas J Methods of making medical devices
US8702129B2 (en) 2007-04-24 2014-04-22 Hyclone Laboratories, Inc. Sterile connector systems
US20100133807A1 (en) * 2007-04-24 2010-06-03 Hyclone Laboratories, Inc. Sterile connector systems
US7938454B2 (en) 2007-04-24 2011-05-10 Hyclone Laboratories, Inc. Sterile connector systems
US20120204990A1 (en) * 2011-02-16 2012-08-16 Fenwal, Inc. Sterile Docking Device, Medical Fluid Flow System With Sterile Docking Device and Method Of Using Same
US8448992B2 (en) * 2011-02-16 2013-05-28 Fenwal, Inc. Sterile docking device, medical fluid flow system with sterile docking device and method of using same
US9199070B2 (en) 2011-12-21 2015-12-01 Fenwal, Inc. Fluid flow conduits and apparatus and methods for making and joining fluid conduits
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