US3910261A - End-tidal gas analysis apparatus for respirators - Google Patents
End-tidal gas analysis apparatus for respirators Download PDFInfo
- Publication number
- US3910261A US3910261A US478429A US47842974A US3910261A US 3910261 A US3910261 A US 3910261A US 478429 A US478429 A US 478429A US 47842974 A US47842974 A US 47842974A US 3910261 A US3910261 A US 3910261A
- Authority
- US
- United States
- Prior art keywords
- gas
- patient
- beginning
- conduit system
- inspiratory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
- A61B5/0836—Measuring rate of CO2 production
Definitions
- References Cited analysis sample is obtained, following a predetermined UNITED STATES PATENTS time delay, when a patient expires air into a respirator.
- One popular gas analysis system employs a sensor in the expiratory path of a respirator to measure the air flow issuing from a patient and control the operation of the analysis mechanism in response thereto.
- the sensor detects the beginning of expiration, which is character ized by a large outflow of air, and produces a signal to begin sampling the expired gas.
- a timer is provided to delay the sampling long enough for the end-tidal region to be reached, after which sampling takes place for as long as the expiratory air flow remains strong enough to sustain a signal from the sensor. Sampling is terminated when the air flow falls below this level, and the sampling system is reset for the next breath cycle.
- gas samples are obtained at a location comparatively remote from the patient, downstream from the valve which shuts off the expiratory conduit during inspiration, and sampling is not begun until the expiratory phase has terminated and inspiration has been detected. While this system endeavors to eliminate the problems associated with sampling before the end-tidal region has been reached, the advantages of obtaining gas samples directly as they are expired from the patient are lost.
- Another object is the provision of a novel and improved system and method by which gas samples are obtained only during the end-tidal portion of expiration, and which permit samples to be taken over a substantial amount of that portion.
- Still another object is the provision of novel and improved apparatus and a method for analyzing the endtidal portion of expiration in which the acquisition of gas samples is controlled in response to large gas flows.
- an end-tidal gas analysis apparatus and method for use with a respirator of the type having an air source actuated in response to patient demand, and a conduit system including inspiratory and expiratory conduits for respectively delivering air to and receiving air from the patient.
- the apparatus includes a gas analyzing device capable of testing gas within a respirator conduit system, an actuator adapted to initiate operation of the analyzing device a predetermined period of time following the beginning of expiration, and a deactuator which senses the beginning of patient inspiration and rapidly terminates operation of the analyzing device in response thereto.
- the analysis period may be set to occur substantially entirely within the end-tidal period, and to extend over a large portion thereof.
- gas flow rate sensors are disposed in both the inspiratory and expiratory conduits and deliver input signals to a signal processing circuit when gas flows are detected.
- the processing circuit includes an amplifier, a threshold device adapted when its threshold is exceeded to terminate operation of the analyzing device, A.C. coupling between the amplifier and threshold device, and a DC. restoration circuit between the A.C. coupling and the threshold device.
- DC. bias is substantially removed by the restoration circuit from the signal applied to the threshold device, thereby enabling the threshold level to be rapidly exceeded and analysis terminated when inspiration begins.
- a means such as a pump is provided to extract gas samples from the respirator conduit system for delivery to the analysis device.
- expired gas may be obtained directly from the patient while expiration is still going on.
- FIG. 1 is a somewhat idealized graph of a respirator patients breathing cycle, with the CO concentration in the respirator conduit system indicated in dashed lines;
- FIG. 2 is a functional diagram of the analysis apparatus shown in conjunction with a respirator system
- FIG. 3 is a block diagram of electrical circuitry employed in the invention.
- FIG. 4 is a schematic diagram of a processing circuit for controlling the operation of the gas analysis apparatus in response to patient inspiration and expiration.
- FIG. 1 a typical air-flow pattern to and from a patient assisted by a respirator is shown, with inspiration indicated by a negative flow level and expiration by a positive flow level. At the end of inspiration (coinciding with the beginning of expiration),
- time T a large flow of air is expelled by the patient into the respirator.
- the outward air flow gradually tapers off to a very low level, indicated by reference numeral 2, followed by a pause with essentially no air flow until the patient again draws breath at time T Thereafter the breathing sequence continues in a repetitive sequence of inspirations and expirations.
- An indication of the patients arterial CO concentration may be obtained by analyzing his expired breath; this in turn can be accomplished by measuring the CO level in the respirator conduit or air tube network. This latter quantity is indicated by a dashed line in FIG. 1.
- the CO concentration during inspiration indicated by reference numeral 4, is generally that of the ambient atmosphere, or about 0.03%.
- the plateau 6 which extends through approximately the final third of expiration, is referred to as the end-tidal level and is the true indicator of arterial CO concentration. It will be noted from the drawing, however, that the end-tidal region may be reached near or even after the time the expiration flow has fallen to a low level 2. If this flow rate is used to indicate the end of expiration, at which time sampling is terminated, the samples obtained may represent a period prior to the end-tidal region and an artificially low CO reading will result.
- the present invention achieves an accurate end-tidal sample by sensing the beginning of pa tient expiration at T initiating sampling during the end-tidal region at a time T after expiration begins, and rapidly terminating sampling when the next inspiration is sensed at time T Sampling may be conducted during a large portion of the end-tidal region, and con trol functions need be operated only in response to large air flows.
- FIG. 2 A respirator system employing gas analysis apparatus that achieves this result is shown in block diagram form in FIG. 2.
- the respirator includes an air supply device 8, which provides a desired air mix and pumps the air through a check valve 10 into an inspiratory conduit such as plastic tube 12 in response to patient demand.
- Expired air is routed through an expiratory tube 14 to a chamber 16, and thence out of the respirator system through a continuation expiratory tube 18.
- Air is channeled to and from the patient through a tap 20, while an inflatable bladder valve 22 is alternately expanded to close off the exit from expiratory tube 14 during inspiration, and relaxed during expiration to permit the discharge of expired air.
- the novel gas analysis apparatus includes an air pump 24 that is tapped by a tube 26 into the conduit system at a location between valves 10 and 22 where expired air can be extracted, a gas analysis device 28 such as a thermal conductivity cell adapted to receive air from pump 24, and an electronic processing circuit 30 controlling the operation of pump 24.
- a first air flow sensor such as termistor 32 is inserted into continuation expiratory tube 18 to produce a signal for delivery to processing circuit 30 when an expiratory air flow is detected.
- a second sensor such as thermistor 34 is inserted into the inspiratory tube 12 to sense the beginning of patient inspiration and in response deliver a second signal to the processing circuit 30.
- the triggering flow rate for each of the thermistors 32 and 34 is generally from one to two liters per minute, although the trigger levels may be varied as desired.
- this sensor may also be used in the analysis apparatus instead of thermistor 34.
- a bias circuit 36 supplies a voltage sufficient to establish a heating current through the thermistors comprising expiratory sensor 32 and inspiratory sensor 34.
- the expiratory sensor 32 is connected via an A.C. coupling circuit 38 to a threshold comparator 40, where the signal is compared with a reference threshold signal and an output produced for delivery to the set input of a flip-flop 42 when the threshold is ex ceeded.
- the output of the flip-flop is in turn connected to the drive mechanism for pump 24.
- Inspiratory sensor 34 also heated by bias circuit 36, is connected to a D.C. amplifier 44, having a gain factor of 8.5, and thence to an A.C. coupling and D.C. restoration circuit 46, where the A.C. component of the amplified sensor signal undergoes a D.C. shift.
- the output of circuit 46 is applied to a threshold device such as comparator 48, which is turn has an output con nected to reset the flip-flop 42.
- the aforesaid D.C. shift is such that threshold device 48 is rapidly triggered at the beginning of inspiration to produce an output which resets the flip-flop 42.
- a delay circuit 49 receives the set output of flip-flop 42 and, after a predetermined delay period, emits a pulse to energize the drive mechanism for pump 24.
- the delay is set at about two-thirds of the expiratory period, or generally in the area of 7.5 seconds.
- the pump drive energizing signal is rapidly terminated, without appreciable delay, when flip-flop 42 is reset.
- FIG. 4 Circuit details are shown in FIG. 4 of the processing circuit block diagram functions illustrated in FIG. 3.
- a bias voltage of -IS volts is applied to an input terminal 50, which is connected to a resistor 52.
- the expiratory an inspiratory thermistors 32 and 34 are connected between ground and circuit nodes 53 and 54, respectively, and thereafter through resistors 55 and 56 to the other side of resistor 52 from terminal 50.
- the thermistors and their associated resistors are paralleled by a zenor diode 57 and normally carry a current of about 5.3 ma for still air.
- the expiratory thermistor 32 is also A.C.
- comparator 40 coupled to an operational amplifier which serves as comparator 40 through an RC circuit comprising a series connected resistor 58 and capacitor 60 and a further resistor 62 between ground and capacitor 60, the thermistor output being applied at the signal input 64 to comparator 40.
- the reference input 66 of comparator 40 receives a reference signal from a voltage divider circuit which comprises resistors 68 and 70 connected between input terminal 50 and ground.
- the output of comparator 40 is connected via appropriate coupling circuitry to the set input of flip-flop 42, which consists lines, the output 76 of which leads to A.C. coupling and DC. restoration circuit 46, also shown enclosed in dashed lines.
- This latter circuit is formed from a series connected resistor 78 and capacitor 80, together with a diode 82 which provides a conductive path to ground on the far side of the series circuit from amplifier 44.
- the circuit output is connected to the signal input 84 of comparator 48, the reference input 86 of which is supplied with a reference voltage from a voltage divider circuit which comprises resistors 88 and 90 connected between input terminal 50 and ground.
- the output of comparator 48 is connected via appropriate coupling to the other input of flip-flop 42.
- a monostable multivibrator 92 located at the output of flip-flop 42 introduces a delay to the output signal, the duration of the delay being selectively adjustable by means of an'adjustment mechanism 94.
- the output of flip-flop 42 and the multivibrator 92 are fed to an AND gate 96, the output of which is applied to the drive mechanism for air pump 24.
- the respirator functions in the usual manner with inspiratory air flows supplied on patient demand, followed by an expiration period. Immediately before expiration begins, there is little or no air flow past expiratory thermistor 32, and its resistance is relatively low. A steady state voltage of approximately-1.5 volts is thereby established at node 53. The air flow at the beginning of expiration cools thermistor 32, increasing its resistance so that a negative pulse of from about 0.2 to 1.0 volts for the average person is superimposed onto the steady state voltage at node 53. This pulse triggers comparator 40 to set flip-flop 42, delivering an input to multivibrator 92.
- the multivibrator After the predetermined delay period the multivibrator produces an output which, together with the continuing output from flip-flop 42, triggers AND gate 96. This actuates the pump 24, which now begins to extract air from the respirator tube network for delivery to the analyzer 28.
- Diode 82 avoids this problem by becoming conductive during the intervals between inspiration signals, holding the voltage at its anode to about 0.7 volts and charging the capacitor 80. At the appearance of an inspiration pulse, the threshold level of comparator 48 is rapidly exceeded (in a negative direction) so that it produces an output that resets flip-flop 42, thereby removing one of the inputs to AND gate 96 and very rapidly deactuating pump 24.
- End-tidal gas is accumulated in analysis device 28, and an accurate indication of the arterial CO level or other end-tidal char acteristic may be obtained.
- End-tidal gas analysis apparatus suitable for use with a respirator of the type having an air source actuated in response to patient demand and a conduit system which includes inspiratory and expiratory conduits for respectively delivering air to and receiving air from a patient, said apparatus comprising:
- actuator means for supplying gas from said conduit system to said analyzing means, actuator means adapted to sense the beginning of patient expiration and to initiate operation of said gas supplying means after a predetermined delay period following the beginning of said patient expiration, and deactuator means adapted to sense the beginning of patient inspiration-and rapidly terminate operation of said gas supplying means in response thereto,
- said actuator means and deactuator means cooperating to operate said gas supplying means for substantially the full interval between the end of said delay period and the beginning of patient inspiration, and to inhibit operation of said gas supplying means during substantially the full remainder of the time the analysis apparatus is in use.
- said deactuator means includes a flow rate sensor adapted to sense gas flows associated with the beginning of inspiration.
- said gas supplying means includes means for extracting a gas sample from said respirator conduit system for delivery to said analyzing means, the operation of said extracting means being controlled by said actuator means and deactuator means.
- said deactuator means includes a gas flow rate sensor disposable in the inspiratory conduit, said sensor being adapted to produce a signal in response to a gas flow through said inspiratory conduit exceeding a predetermined threshold level, and a processing circuit means for a signal produced by said sensor.
- End-tidal gas analysis apparatus suitable for use with a respirator of the type having an air source actuated in response to patient demand, a conduit system which includes inspiratory and expiratory conduits for respectively delivering air to and receiving air from a patient, and gas flow control valves disposed respectively in said inspiratory and expiratory conduits, said apparatus comprising:
- actuator means adapted to sense the beginning of patient expiration and to initiate operation of said gas suppling means after a predetermined period of time following the beginning of said patient expiration
- deactuator means adapted to sense the beginning of patient inspiration and rapidly terminate operation of said gas supplying means in response thereto
- said actuator means and deactuator means cooperat ing to operate said gas supplying means for substantially the full interval between the end of said delay period and the beginning of patient inspiration, and to inhibit operation of said gas supplying means during substantially the full remainder of the time the analysis apparatus is in use.
- End-tidal gas analysis apparatus suitable for use with a respirator of the type having an air source actuated in response to patient demand and a conduit system which includes inspiratory and expiratory conduits for respectively delivering air to and receiving air from a patient, said apparatus comprising:
- a pump means for pumping gas from said conduit system to said analysis device
- first and second gas flow sensors disposable respectively in said expiratory and inspiratory conduits, said first and second sensors being respectively connected to said signal processing circuit means to provide input signals when the sensed gas flows exceed predetermined threshold rates;
- said signal processing circuit means including means to actuate said pump means after a predetermined period of time following receipt of an input signal from said first sensor, and further including rapid response means to deactuate said pump means in response to an input signal from said second sensor.
- End-tidal gas analysis apparatus suitable for use with the air supply of a respirator, comprising:
- conduit system including inspiratory and expiratory conduits for respectively delivering air from said air supply to and receiving air from a patient
- means for supplying gas from said conduit system to said analyzing means including means for extracting a gas sample from the portion of said conduit system between said flow control valves,
- actuator means adapted to sense the beginning of patient expiration and to initiate operation of said extracting means after a predetermined delay period following the beginning of said patient expiration
- deactuator means adapted to sense the beginning of patient inspiration and rapidly terminate operation of said analyzing means in response thereto.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Obesity (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Physiology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US478429A US3910261A (en) | 1974-06-11 | 1974-06-11 | End-tidal gas analysis apparatus for respirators |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US478429A US3910261A (en) | 1974-06-11 | 1974-06-11 | End-tidal gas analysis apparatus for respirators |
Publications (1)
Publication Number | Publication Date |
---|---|
US3910261A true US3910261A (en) | 1975-10-07 |
Family
ID=23899896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US478429A Expired - Lifetime US3910261A (en) | 1974-06-11 | 1974-06-11 | End-tidal gas analysis apparatus for respirators |
Country Status (1)
Country | Link |
---|---|
US (1) | US3910261A (en) |
Cited By (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4090078A (en) * | 1976-03-13 | 1978-05-16 | Dragerwerk Aktiengesellschaft | Method and arrangement for determining alcohol content in the breath |
US4169465A (en) * | 1977-05-04 | 1979-10-02 | James A. Walls | Method and apparatus for obtaining non-invasive cardio-pulmonary measurements |
US4220162A (en) * | 1978-11-24 | 1980-09-02 | Intermountain Health Care | Alveolar gas sampling system and method |
US4221224A (en) * | 1978-06-29 | 1980-09-09 | Intermountain Health Care | Non-airtight pulmonary measuring device |
US4346584A (en) * | 1980-10-20 | 1982-08-31 | Boehringer John R | Gas analyzer |
US4558708A (en) * | 1984-10-24 | 1985-12-17 | Tri-Med, Inc. | Patient's airway adapter to withdraw a patient's gas samples for testing free of sputum mucus and/or condensed water, by utilizing a hollow cylindrical hydrophobic liquid baffle |
US4579826A (en) * | 1983-09-30 | 1986-04-01 | Bolton Craig E | Method and device for analyzing human breath |
DE3706559A1 (en) * | 1987-02-28 | 1988-09-15 | Buettner Wolfgang Dr | Method and device for measuring and monitoring the parameters in a semi-closed system which are to be complied with in the case of anaesthesia and relate to the spontaneous breathing or the respiration of the anaesthetised person |
EP0328415A1 (en) * | 1988-02-10 | 1989-08-16 | Sherwood Medical Company | Pulmonary function tester |
WO1990009572A1 (en) * | 1989-02-02 | 1990-08-23 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Breath sampler |
US5050615A (en) * | 1988-09-02 | 1991-09-24 | Instrumentarium Corp. | Method for the determination of a gas component content in the respiratory gas of a patient |
US5058601A (en) * | 1988-02-10 | 1991-10-22 | Sherwood Medical Company | Pulmonary function tester |
US5069220A (en) * | 1989-05-26 | 1991-12-03 | Bear Medical Systems, Inc. | Measurement of gas concentration in exhaled breath |
US5081871A (en) * | 1989-02-02 | 1992-01-21 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Breath sampler |
US5170798A (en) * | 1988-02-10 | 1992-12-15 | Sherwood Medical Company | Pulmonary function tester |
JPH05503182A (en) * | 1989-12-15 | 1993-05-27 | ベーリンガー マンハイム コーポレーション | Regulated branch power supply |
US5320093A (en) * | 1990-12-21 | 1994-06-14 | Brigham And Women's Hospital | Rapid anesthesia emergence system using closed-loop PCO2 control |
US5361771A (en) * | 1993-03-05 | 1994-11-08 | Western Research Company, Inc. | Portable pulmonary function testing device and method |
US5383469A (en) * | 1992-01-31 | 1995-01-24 | Board Of Trustees Of The Leland Stanford Junior University | Neonatal hemolysis detection using end-tidal breath sampler and analyzer apparatus |
US5533512A (en) * | 1994-03-18 | 1996-07-09 | Ohmeda Inc. | Method and apparatus for detection of venous air emboli |
US5676132A (en) * | 1995-12-05 | 1997-10-14 | Pulmonary Interface, Inc. | Pulmonary interface system |
WO1997043952A1 (en) * | 1996-05-17 | 1997-11-27 | KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITäT FREIBURG | Process and device for collecting volatile substances in an exhaled respiratory gas |
WO1998026710A1 (en) * | 1996-12-19 | 1998-06-25 | Novametrix Medical Systems, Inc. | Apparatus and method for non-invasively measuring cardiac output |
WO1999020177A1 (en) * | 1997-10-22 | 1999-04-29 | Ids Intelligent Detection Systems, Inc. | A sample collection and detection system used for breath analysis |
US5957128A (en) * | 1996-02-21 | 1999-09-28 | Hecker; Karl-Heinz | Method and device for determination of the functional residual capacity (FRC) |
US6067983A (en) * | 1997-09-19 | 2000-05-30 | Sensormedics Corporation | Method and apparatus for controlled flow sampling from the airway |
US6098622A (en) * | 1998-10-15 | 2000-08-08 | Ntc Technology Inc. | Airway valve to facilitate re-breathing, method of operation, and ventilator circuit so equipped |
US6123674A (en) * | 1998-10-15 | 2000-09-26 | Ntc Technology Inc. | Airway valve to facilitate re-breathing, method of operation, and ventilator circuit so equipped |
US6125848A (en) * | 1997-09-26 | 2000-10-03 | Datex-Ohmeda, Inc. | Distal volume monitoring |
US6129680A (en) * | 1995-06-19 | 2000-10-10 | Btg International Limited | Animal exhalation monitoring |
US6290713B1 (en) | 1999-08-24 | 2001-09-18 | Thomas A. Russell | Flexible illuminators for phototherapy |
EP1083427A3 (en) * | 1999-09-09 | 2001-11-14 | Siemens-Elema AB | Method and apparatus for determining gas content |
US6488635B1 (en) | 1995-06-19 | 2002-12-03 | Btg International Limited | Animal exhalation monitoring |
US6631717B1 (en) | 1999-10-21 | 2003-10-14 | Ntc Technology Inc. | Re-breathing apparatus for non-invasive cardiac output, method of operation, and ventilator circuit so equipped |
US20050149121A1 (en) * | 2003-12-22 | 2005-07-07 | John Crombie | Suture anchoring device |
US20060027236A1 (en) * | 1999-05-12 | 2006-02-09 | Respironics, Inc. | Nasal mask and system using same |
US20060241507A1 (en) * | 2003-06-19 | 2006-10-26 | Carlson Lee R | Breath end- tidal gas monitor |
US20090165785A1 (en) * | 2007-12-29 | 2009-07-02 | Beijing Aeonmed Co., Ltd. | Anesthetic absorbing circle |
US20090320844A1 (en) * | 2006-08-04 | 2009-12-31 | Nielsen Joergen Groenlund | Method to compensate for the effect of recirculation of inert blood soluble gas on the determination of pulmonary blood flow in repeated inert gas rebreathing tests |
US20100212666A1 (en) * | 2006-06-21 | 2010-08-26 | Universitat Bern | System for Controlling Administration of Anaesthesia |
US20100310425A1 (en) * | 2009-06-05 | 2010-12-09 | Piper Medical, Inc. | Real-time indicator detector |
US20110077545A1 (en) * | 2008-06-05 | 2011-03-31 | Filt Lungen- Und Thoraxdiagnostik Gmbh | Portable pneumotachograph for measuring components of an expiration volume |
US20110124115A1 (en) * | 2009-11-24 | 2011-05-26 | Piper Medical Inc | Indication enhanced colorimetric detector |
WO2012059768A1 (en) * | 2010-11-05 | 2012-05-10 | The University Of Manchester | Apparatus and methods for breath sampling |
US8485192B2 (en) | 2005-01-12 | 2013-07-16 | Resmed Limited | Cushion for patient interface |
US8517023B2 (en) | 2007-01-30 | 2013-08-27 | Resmed Limited | Mask system with interchangeable headgear connectors |
US8522784B2 (en) | 2008-03-04 | 2013-09-03 | Resmed Limited | Mask system |
US8844526B2 (en) | 2012-03-30 | 2014-09-30 | Covidien Lp | Methods and systems for triggering with unknown base flow |
US8869797B2 (en) | 2007-04-19 | 2014-10-28 | Resmed Limited | Cushion and cushion to frame assembly mechanism for patient interface |
US8944061B2 (en) | 2005-10-14 | 2015-02-03 | Resmed Limited | Cushion to frame assembly mechanism |
US20150126887A1 (en) * | 2005-02-07 | 2015-05-07 | Aerocrine Ab | Controlling flow of exhaled breath during analysis |
US20150238716A1 (en) * | 2012-09-14 | 2015-08-27 | Fisher & Paykel Healthcare Limited | External sensor arrangement for patient interface |
WO2015031848A3 (en) * | 2013-08-30 | 2015-10-29 | Capnia, Inc. | Universal breath analysis sampling device |
US9364624B2 (en) | 2011-12-07 | 2016-06-14 | Covidien Lp | Methods and systems for adaptive base flow |
US9381316B2 (en) | 2005-10-25 | 2016-07-05 | Resmed Limited | Interchangeable mask assembly |
US9498589B2 (en) | 2011-12-31 | 2016-11-22 | Covidien Lp | Methods and systems for adaptive base flow and leak compensation |
US9649458B2 (en) | 2008-09-30 | 2017-05-16 | Covidien Lp | Breathing assistance system with multiple pressure sensors |
US9808591B2 (en) | 2014-08-15 | 2017-11-07 | Covidien Lp | Methods and systems for breath delivery synchronization |
US9925346B2 (en) | 2015-01-20 | 2018-03-27 | Covidien Lp | Systems and methods for ventilation with unknown exhalation flow |
US9950129B2 (en) | 2014-10-27 | 2018-04-24 | Covidien Lp | Ventilation triggering using change-point detection |
US20180120245A1 (en) * | 2016-10-29 | 2018-05-03 | Sendsor Gmbh | Sensor and Method for Measuring Respiratory Gas Properties |
US9981096B2 (en) | 2013-03-13 | 2018-05-29 | Covidien Lp | Methods and systems for triggering with unknown inspiratory flow |
US10034621B2 (en) | 2011-12-21 | 2018-07-31 | Capnia, Inc. | Collection and analysis of a volume of exhaled gas with compensation for the frequency of a breathing parameter |
US10499819B2 (en) | 2013-01-08 | 2019-12-10 | Capnia, Inc. | Breath selection for analysis |
US10568568B2 (en) | 2014-08-27 | 2020-02-25 | Capnia, Inc. | Methods for immune globulin administration |
US11191449B2 (en) | 2013-08-30 | 2021-12-07 | Capnia, Inc. | Neonatal carbon dioxide measurement system |
US11324954B2 (en) | 2019-06-28 | 2022-05-10 | Covidien Lp | Achieving smooth breathing by modified bilateral phrenic nerve pacing |
US11331004B2 (en) | 2013-02-12 | 2022-05-17 | Capnia, Inc. | Sampling and storage registry device for breath gas analysis |
US11331447B2 (en) | 2008-03-04 | 2022-05-17 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US11340182B2 (en) | 2016-10-29 | 2022-05-24 | Idiag Ag | Breathing apparatus |
US11969552B2 (en) | 2022-06-28 | 2024-04-30 | ResMed Pty Ltd | Mask system with radially positioned vent holes |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3306283A (en) * | 1964-02-27 | 1967-02-28 | Univ Iowa State Res Found Inc | Oxygen utilization analyzer |
US3395701A (en) * | 1965-10-29 | 1968-08-06 | Navy Usa | End tidal sampler for an oxygen breathing mask |
US3401683A (en) * | 1964-11-20 | 1968-09-17 | Webb Associates Inc | Apparatus and method for metabolism measurment |
US3613665A (en) * | 1969-08-08 | 1971-10-19 | Reynolds G Gorsuch | Sampling means for exhaled air |
US3661528A (en) * | 1970-04-02 | 1972-05-09 | Instrumentation Associates Inc | Breath sampler |
-
1974
- 1974-06-11 US US478429A patent/US3910261A/en not_active Expired - Lifetime
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3306283A (en) * | 1964-02-27 | 1967-02-28 | Univ Iowa State Res Found Inc | Oxygen utilization analyzer |
US3401683A (en) * | 1964-11-20 | 1968-09-17 | Webb Associates Inc | Apparatus and method for metabolism measurment |
US3395701A (en) * | 1965-10-29 | 1968-08-06 | Navy Usa | End tidal sampler for an oxygen breathing mask |
US3613665A (en) * | 1969-08-08 | 1971-10-19 | Reynolds G Gorsuch | Sampling means for exhaled air |
US3661528A (en) * | 1970-04-02 | 1972-05-09 | Instrumentation Associates Inc | Breath sampler |
Cited By (149)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4090078A (en) * | 1976-03-13 | 1978-05-16 | Dragerwerk Aktiengesellschaft | Method and arrangement for determining alcohol content in the breath |
US4169465A (en) * | 1977-05-04 | 1979-10-02 | James A. Walls | Method and apparatus for obtaining non-invasive cardio-pulmonary measurements |
US4221224A (en) * | 1978-06-29 | 1980-09-09 | Intermountain Health Care | Non-airtight pulmonary measuring device |
US4220162A (en) * | 1978-11-24 | 1980-09-02 | Intermountain Health Care | Alveolar gas sampling system and method |
US4346584A (en) * | 1980-10-20 | 1982-08-31 | Boehringer John R | Gas analyzer |
US4579826A (en) * | 1983-09-30 | 1986-04-01 | Bolton Craig E | Method and device for analyzing human breath |
US4558708A (en) * | 1984-10-24 | 1985-12-17 | Tri-Med, Inc. | Patient's airway adapter to withdraw a patient's gas samples for testing free of sputum mucus and/or condensed water, by utilizing a hollow cylindrical hydrophobic liquid baffle |
DE3706559A1 (en) * | 1987-02-28 | 1988-09-15 | Buettner Wolfgang Dr | Method and device for measuring and monitoring the parameters in a semi-closed system which are to be complied with in the case of anaesthesia and relate to the spontaneous breathing or the respiration of the anaesthetised person |
US5058601A (en) * | 1988-02-10 | 1991-10-22 | Sherwood Medical Company | Pulmonary function tester |
AU615982B2 (en) * | 1988-02-10 | 1991-10-17 | Sherwood Medical Company | Pulmonary function tester |
EP0328415A1 (en) * | 1988-02-10 | 1989-08-16 | Sherwood Medical Company | Pulmonary function tester |
US5170798A (en) * | 1988-02-10 | 1992-12-15 | Sherwood Medical Company | Pulmonary function tester |
US5050615A (en) * | 1988-09-02 | 1991-09-24 | Instrumentarium Corp. | Method for the determination of a gas component content in the respiratory gas of a patient |
WO1990009572A1 (en) * | 1989-02-02 | 1990-08-23 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Breath sampler |
US5081871A (en) * | 1989-02-02 | 1992-01-21 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Breath sampler |
AU631854B2 (en) * | 1989-02-02 | 1992-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Breath sampler |
US5069220A (en) * | 1989-05-26 | 1991-12-03 | Bear Medical Systems, Inc. | Measurement of gas concentration in exhaled breath |
JPH05503182A (en) * | 1989-12-15 | 1993-05-27 | ベーリンガー マンハイム コーポレーション | Regulated branch power supply |
US5320093A (en) * | 1990-12-21 | 1994-06-14 | Brigham And Women's Hospital | Rapid anesthesia emergence system using closed-loop PCO2 control |
US5383469A (en) * | 1992-01-31 | 1995-01-24 | Board Of Trustees Of The Leland Stanford Junior University | Neonatal hemolysis detection using end-tidal breath sampler and analyzer apparatus |
US5361771A (en) * | 1993-03-05 | 1994-11-08 | Western Research Company, Inc. | Portable pulmonary function testing device and method |
US5533512A (en) * | 1994-03-18 | 1996-07-09 | Ohmeda Inc. | Method and apparatus for detection of venous air emboli |
US6129680A (en) * | 1995-06-19 | 2000-10-10 | Btg International Limited | Animal exhalation monitoring |
US6488635B1 (en) | 1995-06-19 | 2002-12-03 | Btg International Limited | Animal exhalation monitoring |
US5676132A (en) * | 1995-12-05 | 1997-10-14 | Pulmonary Interface, Inc. | Pulmonary interface system |
US5957128A (en) * | 1996-02-21 | 1999-09-28 | Hecker; Karl-Heinz | Method and device for determination of the functional residual capacity (FRC) |
WO1997043952A1 (en) * | 1996-05-17 | 1997-11-27 | KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITäT FREIBURG | Process and device for collecting volatile substances in an exhaled respiratory gas |
US20040049113A1 (en) * | 1996-12-19 | 2004-03-11 | Orr Joseph A. | Apparatus and method for non-invasively measuring cardiac output |
US8096297B2 (en) | 1996-12-19 | 2012-01-17 | Ric Investments, Llc | Apparatus and method for non-invasively measuring caridac output |
US7018340B2 (en) | 1996-12-19 | 2006-03-28 | Ntc Technology Inc. | Apparatus and method for non-invasively measuring cardiac output |
US20050203432A1 (en) * | 1996-12-19 | 2005-09-15 | Orr Joseph A. | Apparatus and method for non-invasively measuring cardiac output |
US20100132710A1 (en) * | 1996-12-19 | 2010-06-03 | Ric Investments, Llc | Apparatus and method for non-invasively measuring caridac output |
US6227196B1 (en) | 1996-12-19 | 2001-05-08 | Ntc Technology Inc. | Apparatus and method for non-invasively measuring cardiac output |
US6908438B2 (en) | 1996-12-19 | 2005-06-21 | Respironics Novametrix, Inc. | Apparatus and method for non-invasively measuring cardiac output |
US20040059239A1 (en) * | 1996-12-19 | 2004-03-25 | Jaffe Michael B. | Apparatus and method for non-invasively measuring cardiac output |
WO1998026710A1 (en) * | 1996-12-19 | 1998-06-25 | Novametrix Medical Systems, Inc. | Apparatus and method for non-invasively measuring cardiac output |
US7686012B2 (en) | 1996-12-19 | 2010-03-30 | Ric Investments, Llc | Apparatus for non-invasively measuring cardiac output |
US6648831B2 (en) | 1996-12-19 | 2003-11-18 | Novametrix Medical Systems, Inc. | Apparatus and method for non-invasively measuring cardiac output |
US6648832B2 (en) | 1996-12-19 | 2003-11-18 | Ntc Technology Inc. | Apparatus and method for non-invasively measuring cardiac output |
US6067983A (en) * | 1997-09-19 | 2000-05-30 | Sensormedics Corporation | Method and apparatus for controlled flow sampling from the airway |
US6125848A (en) * | 1997-09-26 | 2000-10-03 | Datex-Ohmeda, Inc. | Distal volume monitoring |
WO1999020177A1 (en) * | 1997-10-22 | 1999-04-29 | Ids Intelligent Detection Systems, Inc. | A sample collection and detection system used for breath analysis |
US6098622A (en) * | 1998-10-15 | 2000-08-08 | Ntc Technology Inc. | Airway valve to facilitate re-breathing, method of operation, and ventilator circuit so equipped |
US6123674A (en) * | 1998-10-15 | 2000-09-26 | Ntc Technology Inc. | Airway valve to facilitate re-breathing, method of operation, and ventilator circuit so equipped |
US20060027236A1 (en) * | 1999-05-12 | 2006-02-09 | Respironics, Inc. | Nasal mask and system using same |
US7703457B2 (en) | 1999-05-12 | 2010-04-27 | Respironics, Inc | Nasal mask and system using same |
US6290713B1 (en) | 1999-08-24 | 2001-09-18 | Thomas A. Russell | Flexible illuminators for phototherapy |
EP1083427A3 (en) * | 1999-09-09 | 2001-11-14 | Siemens-Elema AB | Method and apparatus for determining gas content |
US6631717B1 (en) | 1999-10-21 | 2003-10-14 | Ntc Technology Inc. | Re-breathing apparatus for non-invasive cardiac output, method of operation, and ventilator circuit so equipped |
US9095276B2 (en) | 2003-06-19 | 2015-08-04 | Capnia, Inc. | Breath end-tidal gas monitor |
US9936897B2 (en) | 2003-06-19 | 2018-04-10 | Capnia, Inc. | Breath end-tidal gas monitor |
US20060241507A1 (en) * | 2003-06-19 | 2006-10-26 | Carlson Lee R | Breath end- tidal gas monitor |
US8021308B2 (en) | 2003-06-19 | 2011-09-20 | Capnia, Inc. | Breath end-tidal gas monitor |
US20050149121A1 (en) * | 2003-12-22 | 2005-07-07 | John Crombie | Suture anchoring device |
US8578935B2 (en) | 2005-01-12 | 2013-11-12 | Resmed Limited | Cushion for patient interface |
US8567404B2 (en) | 2005-01-12 | 2013-10-29 | Resmed Limited | Cushion for patient interface |
US9295800B2 (en) | 2005-01-12 | 2016-03-29 | Resmed Limited | Cushion for patient interface |
US10456544B2 (en) | 2005-01-12 | 2019-10-29 | ResMed Pty Ltd | Cushion for patient interface |
US8616211B2 (en) | 2005-01-12 | 2013-12-31 | Resmed Limited | Cushion for patient interface |
US11607515B2 (en) | 2005-01-12 | 2023-03-21 | ResMed Pty Ltd | Cushion for patient interface |
US8613280B2 (en) | 2005-01-12 | 2013-12-24 | Resmed Limited | Cushion for patient interface |
US8485192B2 (en) | 2005-01-12 | 2013-07-16 | Resmed Limited | Cushion for patient interface |
US8613281B2 (en) | 2005-01-12 | 2013-12-24 | Resmed Limited | Cushion for patient interface |
US8573213B2 (en) | 2005-01-12 | 2013-11-05 | Resmed Limited | Cushion for patient interface |
US8573215B2 (en) | 2005-01-12 | 2013-11-05 | Resmed Limited | Cushion for patient interface |
US8550081B2 (en) | 2005-01-12 | 2013-10-08 | Resmed Limited | Cushion for patient interface |
US8550083B2 (en) | 2005-01-12 | 2013-10-08 | Resmed Limited | Cushion for patient interface |
US8573214B2 (en) | 2005-01-12 | 2013-11-05 | Resmed Limited | Cushion for patient interface |
US8550082B2 (en) | 2005-01-12 | 2013-10-08 | Resmed Limited | Cushion for patient interface |
US8555885B2 (en) | 2005-01-12 | 2013-10-15 | Resmed Limited | Cushion for patient interface |
US20150126887A1 (en) * | 2005-02-07 | 2015-05-07 | Aerocrine Ab | Controlling flow of exhaled breath during analysis |
US9919123B2 (en) * | 2005-02-07 | 2018-03-20 | Circassia Ab | Controlling flow of exhaled breath during analysis |
US20180243523A1 (en) * | 2005-02-07 | 2018-08-30 | Circassia Ab | Controlling flow of exhaled breath during analysis |
US8944061B2 (en) | 2005-10-14 | 2015-02-03 | Resmed Limited | Cushion to frame assembly mechanism |
US11529487B2 (en) | 2005-10-14 | 2022-12-20 | ResMed Pty Ltd | Cushion to frame assembly mechanism |
US10434273B2 (en) | 2005-10-14 | 2019-10-08 | ResMed Pty Ltd | Cushion to frame assembly mechanism |
US11833305B2 (en) | 2005-10-14 | 2023-12-05 | ResMed Pty Ltd | Cushion/frame assembly for a patient interface |
US10137270B2 (en) | 2005-10-14 | 2018-11-27 | Resmed Limited | Cushion to frame assembly mechanism |
US11369765B2 (en) | 2005-10-14 | 2022-06-28 | ResMed Pty Ltd | Cushion to frame assembly mechanism |
US11633564B2 (en) | 2005-10-14 | 2023-04-25 | ResMed Pty Ltd | Cushion to frame assembly mechanism |
US9962510B2 (en) | 2005-10-25 | 2018-05-08 | Resmed Limited | Respiratory mask assembly |
US9381316B2 (en) | 2005-10-25 | 2016-07-05 | Resmed Limited | Interchangeable mask assembly |
US11052211B2 (en) | 2005-10-25 | 2021-07-06 | ResMed Pty Ltd | Interchangeable mask assembly |
US11890418B2 (en) | 2005-10-25 | 2024-02-06 | ResMed Pty Ltd | Interchangeable mask assembly |
US11596757B2 (en) | 2005-10-25 | 2023-03-07 | ResMed Pty Ltd | Interchangeable mask assembly |
US10183138B2 (en) | 2005-10-25 | 2019-01-22 | Resmed Limited | Interchangeable mask assembly |
US20100212666A1 (en) * | 2006-06-21 | 2010-08-26 | Universitat Bern | System for Controlling Administration of Anaesthesia |
US8201557B2 (en) * | 2006-08-04 | 2012-06-19 | Innovision A/S | Method to compensate for the effect of recirculation of inert blood soluble gas on the determination of pulmonary blood flow in repeated inert gas rebreathing tests |
US20090320844A1 (en) * | 2006-08-04 | 2009-12-31 | Nielsen Joergen Groenlund | Method to compensate for the effect of recirculation of inert blood soluble gas on the determination of pulmonary blood flow in repeated inert gas rebreathing tests |
US8960196B2 (en) | 2007-01-30 | 2015-02-24 | Resmed Limited | Mask system with interchangeable headgear connectors |
US10864342B2 (en) | 2007-01-30 | 2020-12-15 | ResMed Pty Ltd | Mask with removable headgear connector |
US8517023B2 (en) | 2007-01-30 | 2013-08-27 | Resmed Limited | Mask system with interchangeable headgear connectors |
US9937315B2 (en) | 2007-01-30 | 2018-04-10 | Resmed Limited | Mask with removable headgear connector |
US8869797B2 (en) | 2007-04-19 | 2014-10-28 | Resmed Limited | Cushion and cushion to frame assembly mechanism for patient interface |
US10195384B2 (en) | 2007-04-19 | 2019-02-05 | Resmed Limited | Cushion and cushion to frame assembly mechanism for patient interface |
US20090165785A1 (en) * | 2007-12-29 | 2009-07-02 | Beijing Aeonmed Co., Ltd. | Anesthetic absorbing circle |
US8176914B2 (en) * | 2007-12-29 | 2012-05-15 | Beijing Aeonmed Co., Ltd. | Anesthetic absorbing circle |
US8522784B2 (en) | 2008-03-04 | 2013-09-03 | Resmed Limited | Mask system |
US9757533B2 (en) | 2008-03-04 | 2017-09-12 | Resmed Limited | Mask system with snap-fit shroud |
US8550084B2 (en) | 2008-03-04 | 2013-10-08 | Resmed Limited | Mask system |
US11833277B2 (en) | 2008-03-04 | 2023-12-05 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US11077274B2 (en) | 2008-03-04 | 2021-08-03 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US9950131B2 (en) | 2008-03-04 | 2018-04-24 | Resmed Limited | Mask system with snap-fit shroud |
US10751496B2 (en) | 2008-03-04 | 2020-08-25 | ResMed Pty Ltd | Mask system with shroud |
US9962511B2 (en) | 2008-03-04 | 2018-05-08 | Resmed Limited | Mask system with snap-fit shroud |
US11395893B2 (en) | 2008-03-04 | 2022-07-26 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US11331447B2 (en) | 2008-03-04 | 2022-05-17 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US8528561B2 (en) | 2008-03-04 | 2013-09-10 | Resmed Limited | Mask system |
US9027556B2 (en) | 2008-03-04 | 2015-05-12 | Resmed Limited | Mask system |
US11305085B2 (en) | 2008-03-04 | 2022-04-19 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US11529486B2 (en) | 2008-03-04 | 2022-12-20 | ResMed Pty Ltd | Mask system with shroud having extended headgear connector arms |
US11529488B2 (en) | 2008-03-04 | 2022-12-20 | ResMed Pty Ltd | Mask system with snap-fit shroud |
US9119931B2 (en) | 2008-03-04 | 2015-09-01 | Resmed Limited | Mask system |
US9770568B2 (en) | 2008-03-04 | 2017-09-26 | Resmed Limited | Mask system with snap-fit shroud |
US20110077545A1 (en) * | 2008-06-05 | 2011-03-31 | Filt Lungen- Und Thoraxdiagnostik Gmbh | Portable pneumotachograph for measuring components of an expiration volume |
US20160256072A1 (en) * | 2008-06-05 | 2016-09-08 | Aerocrine Ab | Portable pneumotachograph for measuring components of an expiration volume |
US9649458B2 (en) | 2008-09-30 | 2017-05-16 | Covidien Lp | Breathing assistance system with multiple pressure sensors |
US20100310425A1 (en) * | 2009-06-05 | 2010-12-09 | Piper Medical, Inc. | Real-time indicator detector |
US20110124115A1 (en) * | 2009-11-24 | 2011-05-26 | Piper Medical Inc | Indication enhanced colorimetric detector |
WO2012059768A1 (en) * | 2010-11-05 | 2012-05-10 | The University Of Manchester | Apparatus and methods for breath sampling |
US10543327B2 (en) | 2011-12-07 | 2020-01-28 | Covidien Lp | Methods and systems for adaptive base flow |
US11497869B2 (en) | 2011-12-07 | 2022-11-15 | Covidien Lp | Methods and systems for adaptive base flow |
US9364624B2 (en) | 2011-12-07 | 2016-06-14 | Covidien Lp | Methods and systems for adaptive base flow |
US10034621B2 (en) | 2011-12-21 | 2018-07-31 | Capnia, Inc. | Collection and analysis of a volume of exhaled gas with compensation for the frequency of a breathing parameter |
US10709854B2 (en) | 2011-12-31 | 2020-07-14 | Covidien Lp | Methods and systems for adaptive base flow and leak compensation |
US11833297B2 (en) | 2011-12-31 | 2023-12-05 | Covidien Lp | Methods and systems for adaptive base flow and leak compensation |
US9498589B2 (en) | 2011-12-31 | 2016-11-22 | Covidien Lp | Methods and systems for adaptive base flow and leak compensation |
US10029057B2 (en) | 2012-03-30 | 2018-07-24 | Covidien Lp | Methods and systems for triggering with unknown base flow |
US8844526B2 (en) | 2012-03-30 | 2014-09-30 | Covidien Lp | Methods and systems for triggering with unknown base flow |
US11135381B2 (en) | 2012-09-14 | 2021-10-05 | Fisher & Paykel Healthcare Limited | External sensor arrangement for patient interface |
US10124134B2 (en) * | 2012-09-14 | 2018-11-13 | Fisher & Paykel Healthcare Limited | External sensor arrangement for patient interface |
US20150238716A1 (en) * | 2012-09-14 | 2015-08-27 | Fisher & Paykel Healthcare Limited | External sensor arrangement for patient interface |
US10499819B2 (en) | 2013-01-08 | 2019-12-10 | Capnia, Inc. | Breath selection for analysis |
US11331004B2 (en) | 2013-02-12 | 2022-05-17 | Capnia, Inc. | Sampling and storage registry device for breath gas analysis |
US9981096B2 (en) | 2013-03-13 | 2018-05-29 | Covidien Lp | Methods and systems for triggering with unknown inspiratory flow |
WO2015031848A3 (en) * | 2013-08-30 | 2015-10-29 | Capnia, Inc. | Universal breath analysis sampling device |
US11191449B2 (en) | 2013-08-30 | 2021-12-07 | Capnia, Inc. | Neonatal carbon dioxide measurement system |
US9808591B2 (en) | 2014-08-15 | 2017-11-07 | Covidien Lp | Methods and systems for breath delivery synchronization |
US10864336B2 (en) | 2014-08-15 | 2020-12-15 | Covidien Lp | Methods and systems for breath delivery synchronization |
US10568568B2 (en) | 2014-08-27 | 2020-02-25 | Capnia, Inc. | Methods for immune globulin administration |
US11712174B2 (en) | 2014-10-27 | 2023-08-01 | Covidien Lp | Ventilation triggering |
US10940281B2 (en) | 2014-10-27 | 2021-03-09 | Covidien Lp | Ventilation triggering |
US9950129B2 (en) | 2014-10-27 | 2018-04-24 | Covidien Lp | Ventilation triggering using change-point detection |
US9925346B2 (en) | 2015-01-20 | 2018-03-27 | Covidien Lp | Systems and methods for ventilation with unknown exhalation flow |
US20180120245A1 (en) * | 2016-10-29 | 2018-05-03 | Sendsor Gmbh | Sensor and Method for Measuring Respiratory Gas Properties |
US10852261B2 (en) * | 2016-10-29 | 2020-12-01 | Sendsor Gmbh | Sensor and method for measuring respiratory gas properties |
US11340182B2 (en) | 2016-10-29 | 2022-05-24 | Idiag Ag | Breathing apparatus |
US11324954B2 (en) | 2019-06-28 | 2022-05-10 | Covidien Lp | Achieving smooth breathing by modified bilateral phrenic nerve pacing |
US11969552B2 (en) | 2022-06-28 | 2024-04-30 | ResMed Pty Ltd | Mask system with radially positioned vent holes |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3910261A (en) | End-tidal gas analysis apparatus for respirators | |
US4106503A (en) | Metering system for stimulating bronchial spasm | |
US6510851B2 (en) | Method and arrangement for evaluating effective flow resistance of patient breathing circuit | |
US5069220A (en) | Measurement of gas concentration in exhaled breath | |
US4281651A (en) | Lung ventilator | |
US5307795A (en) | Medical ventilators | |
US5497767A (en) | Method and apparatus for supplying fresh gas to a patient during manual ventilation | |
US8371298B2 (en) | Method and apparatus for lung volume estimation | |
JP3781841B2 (en) | Ventilator for artificial respiration therapy | |
US8796034B2 (en) | Apparatus and method for diagnostic gas analysis | |
US6240920B1 (en) | Method for determining a parameter related to spontaneous breathing efforts by a subject, and breathing-assist apparatus operating in accordance with the method | |
US3621833A (en) | Method and apparatus for automatically determining physiological parameters related to human breathing airway resistance and functional residual capacity | |
US5303700A (en) | Method for detecting the respiratory phases of a patient during an assisted ventilating process | |
US5957128A (en) | Method and device for determination of the functional residual capacity (FRC) | |
EP0459647B1 (en) | Apparatus and method for flow triggering of breath supported ventilation | |
EP1083427A2 (en) | Method and apparatus for determining gas content | |
US7364552B2 (en) | Measuring system for the determination of the concentration of propofol (2,6-diisopropylphenol) in the respiratory flow | |
US3961624A (en) | Method of determining lung pressure of a patient using a positive pressure breathing system | |
US4535780A (en) | Apparatus for measuring xenon concentration in xenon cerebral blood-flow studies | |
CN104391107A (en) | Method for measuring nitric oxide in expired gas without need of controlling expiratory flow | |
GB2044451A (en) | Breath test device | |
DE2428352B2 (en) | ARRANGEMENT FOR DETERMINING THE ALCOHOL CONCENTRATION OF THE BLOOD BY MEASURING THE ALCOHOL CONCENTRATION OF THE BREATHING AIR | |
JP2740234B2 (en) | Lung function tester | |
EP3210534B1 (en) | Method for measuring energy expenditure using indirect calorimetry | |
KR20200077639A (en) | Apparatus for measuring gas concentration and Method for measuring gas concentration using the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: BOURNS MEDICAL SYSTEMS, INC., A CORP. OF CA. Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:BOURNS MEDICAL SYSTEMS, INC., A CORP. OF UTAH;REEL/FRAME:003860/0419 Effective date: 19810519 |
|
AS | Assignment |
Owner name: BEAR MEDICAL SYSTEMS, INC., Free format text: CHANGE OF NAME;ASSIGNOR:BOURNS MEDICAL SYSTEMS, INC.;REEL/FRAME:003915/0722 Effective date: 19810915 Owner name: BEAR MEDICAL SYSTEMS, INC.,, STATELESS Free format text: CHANGE OF NAME;ASSIGNOR:BOURNS MEDICAL SYSTEMS, INC.;REEL/FRAME:003915/0722 Effective date: 19810915 |