|Publication number||US3861391 A|
|Publication date||21 Jan 1975|
|Filing date||20 Mar 1974|
|Priority date||2 Jul 1972|
|Publication number||US 3861391 A, US 3861391A, US-A-3861391, US3861391 A, US3861391A|
|Inventors||Antonevich John N, Goodfriend Roger|
|Original Assignee||Blackstone Corp|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (5), Referenced by (106), Classifications (9), Legal Events (4)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent Antonevich et al.
1451 Jan. 21, 1975 APPARATUS FOR DISINTEGRATION OF URINARY CALCULI Inventors: John N. Antonevich, Jamestown,
N.Y.; Roger Goodfriend, San Jose,
Assignee: Blackstone Corporation, Jamestown,
Filed: Mar. 20, 1974 Appl. No.: 453,063
Related US. Application Data Division of Ser. No. 273,985, July 2, 1972, Pat. No. 3,830,240.
US. Cl. 128/328, 128/24 A Int. Cl A6111 17/22 Field of Search 128/24 A, 328
 References Cited UNITED STATES PATENTS 2,227,727 1/1941 Leggiadro 1211/3211 x 3,413,976 12/1968 ROze 123/3211 3,543,757 12/1970 Balaev et al. Q8/3212 3,584,327 6/1971 Murry 128/24 A X 3,735,764 5/1973 Balaev et :11. .1 128/328 Primary ExaminerCh-anning L. Pace Attorney, Agent, or FirmBuell, Blenko and Ziesenheim  ABSTRACT A method and apparatus are provided for disintegrating urinary calculi by subjecting the urinary calculi to ultrasonic forces transmitted transversely of a wave guide in a catheter.
6 Claims, 13 Drawing Figures APPARATUS FOR DISINTEGRATION OF URINARY CALCULI This is a division of application Ser. No. 273,985, filed July 21, 1972, now US. Pat. No. 3,830,240 dated Aug. 20, 1974.
This invention relates to methods and apparatus for disintegration of urinary calculi and particularly to an ultrasonic method and apparatus for fragmenting or drilling through urinary calculi.
It is well known that the average number of hospital admissions for removal of urinary calculi or stones is about 1 per 1000 of population per year. This means that there are in excess of 200,000 cases of urinary calculi requiring hospital care. Stones which are quite small may in some cases be passed without hospitalization. However, all stones and particularly larger stones, especially if associated with obstruction or infection, must be removed from the urinary tract to prevent renal damage. Stones which are lodged low in the ureter may often be removed by manipulation using devices which are passed through the ureter up to the stone where they engage the stone for mechanical extraction. When the stone is high in the ureter or remains in the kidney, then it must be removed with open surgery in present practices.
The present invention eliminates the need for surgical removal of urinary calculi and reduces the hazards of mechanical manipulation in removing stones from the urinary tract.
The idea of vibratory impact machining of urinary calculi is not new. At least as early as 1946 proposals for vibratory impact machining of stones obstructing urinary tracts were made. Thereafter many investigators worked on techniques for ultrasonic disintegration of such urinary calculi. Focused beam techniques on distal stones were difficult to control and results were questionable. Impact machining techniques by transmitting longitudinal vibrations through wire wave guides were found to be effective to some degree but much too slow to be practical. Moreover, such methods were difficult to control and greatly restricted in utility because of excessive heat generation along the wave guide and the very large size of the wire used in order to provide longitudinal vibration.
We have found that urinary calculi can be quickly fragmented or drilled through if a wave guide is passed through the lumen of a catheter in the ureter so that both catheter and wave guide touch the calculi to be fragmented and the relative size of the wave guide with respect to the catheter in such that lateral motion of the wave guide within the catheter at the stone is possible. We have found that with such an arrangement large urinary calculi can be quickly fragmented and removed, usually in 2 to 60 seconds.
In the practice of our invention a catheter is passed cystoscopically to the side of the stone in the urinary tract, a wave guide is passed through the lumen of the catheter and both are made to contact the stone, the wave guide being of such size as to provide lateral motion of the guide within the catheter, an ultrasonic transducer is attached to the wave guide and energized setting the guide into longitudinal and transverse vibration thereby causing an impaction and scraping action of the free end of the guide on the stone resulting in fragmentation or drilling of the stone. Preferably the wave guide is a wire. The cutting area may be irrigated or cooled by passing flushing fluid through the catheter around the wave guide. Preferably the apparatus consists of hollow catheter means adapted to enter the ureter and contact the stone, wave guide means having a diameter smaller than the hollow portion of the catheter means ana adapted to pass through said hollow catheter means to contact the stone, and transducer means engaging the wave guide at the end opposite the stone and imparting both lateral and transverse motion to the wave guide at the end contacting the stone.
In the foregoing general description of our invention we have set out certain objects, purposes and advantages. Other objects, purposes and advantages will be apparent from a consideration of the following description and the accompanying drawings in which:
FIG. I illustrates the apparatus of this invention, partly in section in place in a human urinary system for removing a stone;
FIGS. 2 (a) through 2 (f) illustrates fragmentarily several embodiments of coupling between transducer and wave guide;
FIG. 3 is a side elevational view of an apparatus for controlled fragmentation of stones;
FIG. 4 is a section through a connector for a catheter and wave guide for introducing flush solution into the catheter; and
FIGS. 5 (a) through 5 (d) illustrates in side elevation several embodiments of wave guide cutting and fragmentary ends.
Referring to the drawings we have illustrated a cystoscope I0 inserted through a urethra 11 into a bladder 12. A catheter I3 is inserted through the cystoscope 10, the bladder 12 and into a ureter 14 until its end contacts stone 15. At this point a wave guide in the form ofwire 16 is inserted through the catheter until its end contacts the stone 15. The wire I6 must be of substantially smaller diameter than the lumen diameter of the catheter, preferably less than two-thirds of the lumen diameter. The free end 16a of the wire I6 is attached to a transducer 17 by a set screw 18 or it may simply be abutted against the transducer with the transducer being urged toward the stone to put pressure on the wave guide.
With the catheter and wave guide in fixed position against the stone, the cystoscope is moved to the position which provides the least amount of curvature in the catheter and wave guide. An X-ray picture of the urinary tract is preferably taken at this point to assure contact of the catheter and wave guide with the stone. At this point with contact assured the transducer is energized and the catheter and wave guide are both pushed gently toward the stone until the wave guide has moved a distance equal to the estimated thickness of the stone.
We have found that coupling of the transducer 17 with the wire 16 can take various forms. The transducer can be directly mechanically connected as shown in FIG. 2(a) using a set screw or similar means. This is in general our preferred connection. Due to the high slenderness ration of the guide (wire), this coupling will, above a threshold ultrasonic displacement velocity lead to instability resulting in conversion of longitudi nal motion into transverse motion of the guide, which is desired in the practice of this invention. The same is true of the embodiment of FIG. 2(b) where there is no mechanical attachment between the transducer and wire and coupling is achieved by the force pushing against the wire end to force the wire into contact with the stone. The connections shown in FIGS. 2(6), 2(d) and 2(e) provide indirect conversion of the transducer motion into combined longitudinal and transverse, longitudinal and transverse torsional and longitudinal and transverse ellipsoidal motion respectively at the free end of the wire when it contacts the stone. The connection shown at 2(j) converts the longitudinal motion of the transducer into transverse motion.
In order to better control the position of the catheter and wave guide at the distal point which may be 40 cm. from the transducer we provide a control apparatus shown in the modification of FIG. 3. In this embodiment those elements which are identical with elements of FIG. I bear like reference numerals with the addition of a prime sign. Referring to FIG. 3, the catheter 13' and wave guide 16' are positioned at the stone as described in connection with FIG. 1 above. The exposed ends of the catheter and wire guide are fixed in a T-connector 20 provided with an O-ring 21 to seal around the catheter 13 without collapsing the catheter end. A puncturable rubber diaphragm 22 is placed at the opposite end of the T and the wire 16 is passed therethrough. A viscous grease such as silicon vacuum grease seals the puncture in the diaphragm through which the wire passes so that gasses or liquids may be pumped through the side arm of the T to cool or flush the stone area. The T member 20 is fixed in a clamp 24 mounted on a tilting base 25 which carries a slide 26 on which is mounted transducer assembly 17'. The slide 26 is controlled by micrometer feed 27 to apply pressure through the transducer 17', the wire 16' to the stone 15'. The micrometer 27 allows a fixed controlled feed of wire against the stone and reduces the chance of the wire going through the stone and accidentally penetrating the ureter.
In order to obtain the maximum efficiency while reducing the likelihood of accidental penetration of the ureter. the wire end illustrated in FIG. 5 have been used by us with success. These ends are designed to center the wire end in the catheter to prevent by-passing the stone. In addition, some of these ends by rotation after drilling through the stone can be used to reverse drill and thus create a better chance of breaking the stone or they may be used to pull the stone out of the ureter.
We have also found that an expandable catheter aids in centering the wire and in preventing accidental penetration of the ureter. Such a catheter can be provided with a double wall construction, the outer wall being relatively thin and elastic and enlarged by introducing air or gas between the two walls after the catheter is placed in contact with the stone.
In the foregoing specification we have set out certain preferred practices and embodiments of our invention, however the invention may be otherwise practiced within the scope of the following claims.
I. An apparatus for fragmenting and drilling urinary calculi comprising a catheter adapted to be inserted into a ureter to abut the calculi to be removed, a coupling member extending lengthwise of the lumen of said catheter and having a diameter less than the diameter of said lumen whereby said coupling member may vibrate transversely within the catheter, ultrasonic means acting on the coupling member to cause trans verse vibration of the end thereof adjacent the calculi, and means engaging the end of the catheter remote from the calculi whereby said end is immobilized relatively to the ultrasonic means and the ultrasonic means is mounted on a slide movable at a controlled rate to and from said catheter.
2. An apparatus as claimed in claim I wherein the ultrasonic means is mounted on a slide and micrometer feed means act on the slide to provide a controlled rate of movement of the ultrasonic means toward and away from the end of the catheter.
3. An apparatus as claimed in claim 2 wherein the end of the said end of the catheter is mounted in a clamp on a tilting base carrying the slide and ultrasonic means mounted thereon.
4. An apparatus as claimed in claim 3 wherein the ultrasonic means is a transducer.
5. An apparatus as claimed in claim I wherein the coupling member is less than two-thirds the diameter of the lumen.
6. An apparatus as claimed in claim 1 wherein the coupling member is a wire.
k i I =0
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US2227727 *||11 Apr 1938||7 Jan 1941||Leggiadro Vincent||Lithotrite|
|US3413976 *||29 Jul 1963||3 Dec 1968||G Elektrotekhnichesky Zd Vef||Arrangement for removal of concretions from urinary tract|
|US3543757 *||6 Apr 1965||1 Dec 1970||Ediny Jury Grigorievich||Instrument for crushing concretions in the urinary bladder|
|US3584327 *||4 Apr 1969||15 Jun 1971||Fibra Sonics||Ultrasonic transmission system|
|US3735764 *||23 Nov 1970||29 May 1973||Balev O||Instrument for crushing stones in urinary bladder|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US4192294 *||11 Oct 1977||11 Mar 1980||Gekhman Boris S||Method of removing concretions from the ureter|
|US4474180 *||13 May 1982||2 Oct 1984||The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration||Apparatus for disintegrating kidney stones|
|US4589415 *||31 Aug 1984||20 May 1986||Haaga John R||Method and system for fragmenting kidney stones|
|US4684369 *||19 Aug 1985||4 Aug 1987||Wildemeersch Dirk A A||Instrument for suprapubic drainage of the bladder, inserted through the urethra|
|US4870953 *||13 Nov 1987||3 Oct 1989||Donmicheal T Anthony||Intravascular ultrasonic catheter/probe and method for treating intravascular blockage|
|US4920954 *||5 Aug 1988||1 May 1990||Sonic Needle Corporation||Ultrasonic device for applying cavitation forces|
|US4989588 *||27 Feb 1987||5 Feb 1991||Olympus Optical Co., Ltd.||Medical treatment device utilizing ultrasonic wave|
|US5047043 *||7 Dec 1989||10 Sep 1991||Olympus Optical Co., Ltd.||Resecting device for living organism tissue utilizing ultrasonic vibrations|
|US5103556 *||14 Sep 1990||14 Apr 1992||Circon Corporation||Method of manufacturing an electrohydraulic probe|
|US5154722 *||14 Sep 1990||13 Oct 1992||Circon Corporation||Electrohydraulic probe having a controlled discharge path|
|US5163421 *||12 Dec 1989||17 Nov 1992||Angiosonics, Inc.||In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging|
|US5248296 *||24 Dec 1990||28 Sep 1993||Sonic Needle Corporation||Ultrasonic device having wire sheath|
|US5267954 *||5 May 1992||7 Dec 1993||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5304115 *||11 Jan 1991||19 Apr 1994||Baxter International Inc.||Ultrasonic angioplasty device incorporating improved transmission member and ablation probe|
|US5312328 *||9 Jul 1992||17 May 1994||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5324255 *||10 Jul 1992||28 Jun 1994||Baxter International Inc.||Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm|
|US5342292 *||24 May 1993||30 Aug 1994||Baxter International Inc.||Ultrasonic ablation device adapted for guidewire passage|
|US5344395 *||24 Jan 1992||6 Sep 1994||Scimed Life Systems, Inc.||Apparatus for intravascular cavitation or delivery of low frequency mechanical energy|
|US5368557 *||5 May 1993||29 Nov 1994||Baxter International Inc.||Ultrasonic ablation catheter device having multiple ultrasound transmission members|
|US5368558 *||3 Jun 1993||29 Nov 1994||Baxter International Inc.||Ultrasonic ablation catheter device having endoscopic component and method of using same|
|US5380273 *||19 May 1993||10 Jan 1995||Dubrul; Will R.||Vibrating catheter|
|US5380274 *||12 Oct 1993||10 Jan 1995||Baxter International Inc.||Ultrasound transmission member having improved longitudinal transmission properties|
|US5382228 *||28 Sep 1993||17 Jan 1995||Baxter International Inc.||Method and device for connecting ultrasound transmission member (S) to an ultrasound generating device|
|US5390678 *||12 Oct 1993||21 Feb 1995||Baxter International Inc.||Method and device for measuring ultrasonic activity in an ultrasound delivery system|
|US5397301 *||19 Jul 1993||14 Mar 1995||Baxter International Inc.||Ultrasonic angioplasty device incorporating an ultrasound transmission member made at least partially from a superelastic metal alloy|
|US5405318 *||28 Sep 1993||11 Apr 1995||Baxter International Inc.||Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels|
|US5417672 *||4 Oct 1993||23 May 1995||Baxter International Inc.||Connector for coupling an ultrasound transducer to an ultrasound catheter|
|US5427118 *||4 Oct 1993||27 Jun 1995||Baxter International Inc.||Ultrasonic guidewire|
|US5447509 *||4 Oct 1993||5 Sep 1995||Baxter International Inc.||Ultrasound catheter system having modulated output with feedback control|
|US5474530 *||8 Jun 1994||12 Dec 1995||Baxter International Inc.||Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasospasm|
|US5725570 *||29 Feb 1996||10 Mar 1998||Boston Scientific Corporation||Tubular medical endoprostheses|
|US6277084||5 May 1997||21 Aug 2001||Boston Scientific Corporation||Ultrasonic medical device|
|US6283981||6 Apr 2000||4 Sep 2001||Ethicon Endo-Surgery||Method of balancing asymmetric ultrasonic surgical blades|
|US6287271||9 Jan 1998||11 Sep 2001||Bacchus Vascular, Inc.||Motion catheter|
|US6287331||12 May 1998||11 Sep 2001||Boston Scientific Corporation||Tubular medical prosthesis|
|US6290721||21 Oct 1997||18 Sep 2001||Boston Scientific Corporation||Tubular medical endoprostheses|
|US6309400||29 Jun 1998||30 Oct 2001||Ethicon Endo-Surgery, Inc.||Curved ultrasonic blade having a trapezoidal cross section|
|US6328751||8 Feb 2000||11 Dec 2001||Ethicon Endo-Surgery, Inc.||Balanced ultrasonic blade including a plurality of balance asymmetries|
|US6436115||12 Sep 2000||20 Aug 2002||Jean M. Beaupre||Balanced ultrasonic blade including a plurality of balance asymmetries|
|US6497709||5 May 1997||24 Dec 2002||Boston Scientific Corporation||Metal medical device|
|US6508782||16 Aug 2000||21 Jan 2003||Bacchus Vascular, Inc.||Thrombolysis device|
|US6527802||23 Sep 1997||4 Mar 2003||Scimed Life Systems, Inc.||Clad composite stent|
|US6551337||19 Jul 2000||22 Apr 2003||Omnisonics Medical Technologies, Inc.||Ultrasonic medical device operating in a transverse mode|
|US6617760 *||3 Mar 2000||9 Sep 2003||Cybersonics, Inc.||Ultrasonic resonator|
|US6660013||5 Oct 2001||9 Dec 2003||Omnisonics Medical Technologies, Inc.||Apparatus for removing plaque from blood vessels using ultrasonic energy|
|US6660017||21 May 2001||9 Dec 2003||Ethicon Endo-Surgery, Inc.||Balanced ultrasonic blade including a singular balance asymmetry|
|US6689086||29 Jul 1999||10 Feb 2004||Advanced Cardiovascular Systems, Inc.||Method of using a catheter for delivery of ultrasonic energy and medicament|
|US6689087||28 Mar 2002||10 Feb 2004||Cybersonics, Inc.||Floating probe for ultrasonic transducers|
|US6695782||11 Oct 2001||24 Feb 2004||Omnisonics Medical Technologies, Inc.||Ultrasonic probe device with rapid attachment and detachment means|
|US6733451||25 Mar 2003||11 May 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic probe used with a pharmacological agent|
|US6866670||6 Aug 2003||15 Mar 2005||Omnisonics Medical Technologies, Inc.||Apparatus for removing plaque from blood vessels using ultrasonic energy|
|US6929632||27 Jun 2002||16 Aug 2005||Advanced Cardiovascular Systems, Inc.||Ultrasonic devices and methods for ablating and removing obstructive matter from anatomical passageways and blood vessels|
|US6936025||1 Nov 2000||30 Aug 2005||Bacchus Vascular, Inc.||Thrombolysis device|
|US6958070||18 Oct 2001||25 Oct 2005||Witt David A||Curved clamp arm tissue pad attachment for use with ultrasonic surgical instruments|
|US6976969||14 Jan 2002||20 Dec 2005||Ethicon Endo-Surgery, Inc.||Blades with functional balance asymmetries for use with ultrasonic surgical instruments|
|US7101392||8 Aug 2001||5 Sep 2006||Boston Scientific Corporation||Tubular medical endoprostheses|
|US7300446||20 Jul 2001||27 Nov 2007||Ethicon Endo-Surgery, Inc.||Curved ultrasonic end effector|
|US7387612||4 Dec 2003||17 Jun 2008||Cybersonics, Inc.||Floating probe for ultrasonic transducers|
|US7479148||28 Oct 2005||20 Jan 2009||Crescendo Technologies, Llc||Ultrasonic shear with asymmetrical motion|
|US7494468||21 Feb 2003||24 Feb 2009||Omnisonics Medical Technologies, Inc.||Ultrasonic medical device operating in a transverse mode|
|US7503895||24 Feb 2003||17 Mar 2009||Omnisonics Medical Technologies, Inc.||Ultrasonic device for tissue ablation and sheath for use therewith|
|US7758600||18 Sep 2007||20 Jul 2010||Ethicon Endo-Surgery, Inc.||Balanced ultrasonic end effector|
|US7794414||9 Feb 2004||14 Sep 2010||Emigrant Bank, N.A.||Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes|
|US7803168||9 Dec 2005||28 Sep 2010||The Foundry, Llc||Aortic valve repair|
|US8002782||23 Sep 2005||23 Aug 2011||Ethicon Endo-Surgery, Inc.||Curved clamp arm tissue pad attachment for use with ultrasonic surgical instruments|
|US8021381||23 Jun 2010||20 Sep 2011||Ethicon Endo-Surgery, Inc.||Balanced ultrasonic end effector|
|US8241312||17 Aug 2005||14 Aug 2012||Ethicon Endo-Surgery, Inc.||Blades with functional balance asymmetries for use with ultrasonic surgical instruments|
|US8242398||11 Jun 2008||14 Aug 2012||Sra Developments Limited||Switch for ultrasonic surgical tool|
|US8469982||7 Apr 2011||25 Jun 2013||Ethicon Endo-Surgery, Inc.||Curved clamp arm for use with ultrasonic surgical instruments|
|US8617194||1 Sep 2011||31 Dec 2013||Ethicon Endo-Surgery, Inc.||Balanced ultrasonic end effector|
|US8623040||1 Jul 2009||7 Jan 2014||Alcon Research, Ltd.||Phacoemulsification hook tip|
|US8672959||21 Jun 2013||18 Mar 2014||Ethicon Endo-Surgery, Inc.||Curved clamp arm for use with ultrasonic surgical instruments|
|US8790359||18 May 2007||29 Jul 2014||Cybersonics, Inc.||Medical systems and related methods|
|US8814895||28 Jun 2012||26 Aug 2014||Ethicon Endo-Surgery, Inc.||Blades with functional balance asymmetries for use with ultrasonic surgical instruments|
|US9034032||19 Jul 2013||19 May 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9034033||19 Jul 2013||19 May 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9039757||15 Mar 2013||26 May 2015||Twelve, Inc.||Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods|
|US9044568||20 Jun 2008||2 Jun 2015||Ekos Corporation||Method and apparatus for treatment of intracranial hemorrhages|
|US20010025184 *||4 Apr 2001||27 Sep 2001||Messerly Jeffrey D.||Blades with functional balance asymmetries for use with ultrasonic surgical instruments|
|US20020004665 *||20 Jul 2001||10 Jan 2002||Beaupre Jean M.||Curved ultrasonic blade having a trapezoidal cross section|
|US20020143355 *||14 Jan 2002||3 Oct 2002||Messerly Jeffrey D.||Blades with functional balance asymmetries for use with ultrasonic surgical instruments|
|US20040073244 *||6 Aug 2003||15 Apr 2004||Omnisonics Medical Technologies, Inc.||Method and apparatus for removing plaque from blood vessels using ultrasonic energy|
|US20040082884 *||4 Dec 2003||29 Apr 2004||Dharmendra Pal||Floating probe for ultrasonic transducers|
|US20040097996 *||19 Sep 2003||20 May 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode|
|US20040138740 *||5 Jan 2004||15 Jul 2004||Heath Kevin R||Tubular medical endoprostheses|
|US20040158150 *||2 Feb 2004||12 Aug 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device for tissue remodeling|
|US20040158151 *||4 Feb 2004||12 Aug 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic probe device with rapid attachment and detachment means|
|US20040162571 *||13 Feb 2004||19 Aug 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device to treat deep vein thrombosis|
|US20040249401 *||14 May 2004||9 Dec 2004||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device with a non-compliant balloon|
|US20050043629 *||6 Oct 2004||24 Feb 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device having a probe with a small proximal end|
|US20050043753 *||7 Oct 2004||24 Feb 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device to treat peripheral artery disease|
|US20050096669 *||28 Oct 2004||5 May 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device to treat coronary thrombus bearing lesions|
|US20050119679 *||28 Oct 2004||2 Jun 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device to treat chronic total occlusions|
|US20050143660 *||27 Jan 2005||30 Jun 2005||Omnisonics Medical Technologies, Inc.||Method for removing plaque from blood vessels using ultrasonic energy|
|US20050187513 *||9 Feb 2004||25 Aug 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes|
|US20050187514 *||9 Feb 2004||25 Aug 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic medical device operating in a torsional mode|
|US20050256410 *||14 May 2004||17 Nov 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for an ultrasonic probe capable of bending with aid of a balloon|
|US20050267488 *||13 May 2004||1 Dec 2005||Omnisonics Medical Technologies, Inc.||Apparatus and method for using an ultrasonic medical device to treat urolithiasis|
|US20060020262 *||23 Sep 2005||26 Jan 2006||Witt David A||Curved clamp arm tissue pad attachment for use with ultrasonic surgical instruments|
|EP0243458A1 *||14 Oct 1986||4 Nov 1987||Greenfeld Albert R||Ultrasonic self-cleaning catheter system.|
|EP1219249A1||31 Mar 1994||3 Jul 2002||Ethicon Endo-Surgery, Inc.||Ultrasonic surgical instrument|
|WO1990001300A1 *||27 Jul 1989||22 Feb 1990||Sonic Needle Corp||Ultrasonic device for applying cavitation forces|
|WO1994014382A1 *||22 Dec 1992||7 Jul 1994||Medsonic Inc||Ultrasonic device having wire sheath|
|WO1996039955A1 *||11 Oct 1995||19 Dec 1996||Will R Dubrul||Vibrating catheter|
|WO1999035982A1 *||19 Jan 1999||22 Jul 1999||Michael John Radley Young||Ultrasonic cutting tool|
|WO1999044515A1 *||2 Mar 1999||10 Sep 1999||Mentor Corp||Ultrasonic liposuction probe|
|U.S. Classification||606/128, 601/4|
|International Classification||A61B17/32, A61B18/00, A61B17/22|
|Cooperative Classification||A61B2018/00982, A61B17/22012, A61B2017/320072|
|23 Dec 1996||AS||Assignment|
Owner name: CYBERSONICS, INC., NEW YORK
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SONICSTAR INTERNATIONAL, LTD.;REEL/FRAME:008274/0453
Effective date: 19961216
|23 Dec 1996||AS02||Assignment of assignor's interest|
Owner name: CYBERSONICS, INC. 9 NORTH MAIN STREET JAMESTOWN, N
Effective date: 19961216
Owner name: SONICSTAR INTERNATIONAL, LTD.
|5 Sep 1989||AS||Assignment|
Owner name: BLACKSTONE CORPORATION
Free format text: SECURITY INTEREST;ASSIGNOR:BOND ACQUISITION CORPORATION;REEL/FRAME:005240/0605
Effective date: 19890828
Owner name: ULTRASONICS, INC., NEW YORK
Free format text: SECURITY INTEREST;ASSIGNOR:BLACKSTONE CORPORATION;REEL/FRAME:005240/0600
|5 Sep 1989||AS06||Security interest|
Owner name: BLACKSTONE CORPORATION
Owner name: BOND ACQUISITION CORPORATION
Effective date: 19890828