|Publication number||US3841308 A|
|Publication date||15 Oct 1974|
|Filing date||15 Oct 1973|
|Priority date||15 Oct 1973|
|Publication number||US 3841308 A, US 3841308A, US-A-3841308, US3841308 A, US3841308A|
|Original Assignee||Medical Evaluation Devices & I|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (7), Referenced by (168), Classifications (7), Legal Events (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
[451 Oct. 15, 1974 DISTALLY VALVED CATHETER DEVICE  Inventor: Thomas E. Tate, New Hyde Park,
 Assignee: Medical Evaluation Devices &
' Instruments Corp., Gloversville,
221 Filed: o1.15,1973
 US. Cl..... 128/2 M, 128/250 R, 128/348, 128/D1G. 9  Int. Cl A6lm 25/00  Field of Search 128/2 R, 2 M, 2.05 R, 348, 128/349 R, 350 R, 351, DIG. 9; 251/D1G. 3
[5 6] References Cited UNITED STATES PATENTS 342,275 5/1886 Walters l37/505.22 396,754 H1899 Mayfield 128/349 R 399,540 3/1889 Lee 128/349 R I'IQIV'I'JID. lxiil til 623,022 4/1899 Johnson 128/349 R X 812,020 2/1906 Crippen 27/24 A 2,189,129 2/1940 251/D1G. 3 3,757,768 9/1973 Kline 128/2 M Primary ExaminerDalton L. Truluck Attorney, Agent, or FirmThomas E. Tate  ABSTRACT The disclosure is that of an invention directed to spring guides, catheters, combined guide-catheters or intra-venous feeding tubes in which the distal end is provided with a normally-open proximally-controlled flow shut off valve. The valve is formed as a helically wound spring distal extension with the coils normally separated to define passages for fluid flow therebetween and a proximally operated wire stylette is used to axially contract the spring extension so that the coils thereof are brought into mutual contact, thus closing the passages therebetween.
8 Claims, 14 Drawing Figures I II "a I PATENTEUBBT 1 Sim 3.841.308 SHEH 10? 2 DISTALLY VALVE!) CATHETER DEVICE THE INVENTION This invention relates generally to new and useful improvements in spring guides, catheters, combined guide-catheters or intravenous feeding tubes of the types frequently used for relatively long time retention within a vein or other vessel of an animate being and particularly seeks to provide a novel such device in which the distal end thereof includes a normally-open proximally-controlled flow shut off valve.
Heretofore, in many types of diagnostic tests or subsequent chemo-therapy treatments or intra-venous feedings it has been, and still is, customaryto employ percutaneous techniques for the insertion of spring guides, catheters, combined guide-catherters or intravenous feeding tubes and to withdraw same from the vessel involved after each test or treatment stage has been completed, because none of such devices have been provided with valves for preventing back flow of fluids whenever the use thereof is to be temporarily suspended or for permitting the internal cleaning of such devices between test or treatment stages, even though through the use of external inert coatings, such as those provided by the group of polyfluroethylene compounds, they could otherwise be permitted to remain in place during the interim periods without damaging effects to the vessels involved.
However, in accordance with this invention such devices may be provided with distal end shut off valves so constructed that the initial insertion, retention and ultimate retraction of such devices is not adversely affected, while still permitting the valves to be operated at any desired time.
Therefore, an object of this invention is to provide a novel lumen-containing catheter-like device for insertion into and retention within a blood or other vessel of an animate being and which is provided with a shut off valve at its distal end.
Another object of this invention is to provide a device of the character stated in which the'distal end thereof includes a helically coiled spring of which the helices at the tip thereof are normally separated whereby to permit fluid to flow either into or out of the lumen therof and in which proximally actuated means are provided for axially compacting the normally separated helical coils into contact with each other whereby to shut off fluid flow to or from the lumen.
Another object of this invention is to provide a device of the character stated in which the distal end of the spring is permanently closed and the closure thereof is affixed to the distal end of an internal wire stylette, the proximal end of which extends proximally beyond the proximal end of the entire device whereby to permit proximal movement of the stylette to close the normally open valve.
Another object of this invention is to provide a device of the character stated in which at least the distally valved end thereof is provided with a thin flexible inert sheathing surrounding and bonded to the separated helices of the spring and having a plurality of radial perforations or apertures aligned with the spaces between the normally separated helices to permit free flow of fluid into or out of the spring lumen and to be compactable when the spring tip is proximally retracted into its 1 closed valve status.
Another object of this invention is to provide a device of the character stated in which the inert sheathing thereof is sufficiently thick as to be relatively nonaxially compactable and in which the distal end portion of the sheathing is not bonded to the normally separated distal helices of the spring whereby to permit the separated distal helices of the spring to partake of axial movement relative to the sheath.
Another object of this invention is to provide a device of the character stated in which the closure for the distal end of the spring is axially movable relative thereto and is affixed to the distal end of the wire stylette whereby to permit the closure itself to serve as a valve supplementary to that provided by the normally separated distal helices of the spring.
A further object of this invention is to provide a device of the character stated in which the valve-forming helices of the distal tip may be of progressively reduced radii whereby to form a distally tapering tip.
A further object of this invention is to provide a device of the character stated that is simple in design, rugged in contruction and sufficiently economical to manufacture as to be disposable after a single use, if desired.
With these and other objects, the nature of which will become apparent, the invention will be more fully understood by reference to the drawings, the accompanying detailed description and the appended claims.
In the drawings:
FIG. 1 is a somewhat schematic longitudinal section of the distal end of a valved device constructed in accordance with this invention and shows the valve thereof in its normally open position;
FIG. 2 is a view similar to FIG. 1 but showing the valve in its closed position;
FIG. 3 and 4 are similar to FIGS. 1 and 2- but showing a tapered distal tip;
FIG. 5 is a schematic longitudinal section of a typical completed device showing a fitting at the proximal end for control of the stylette and for connection with an external fluid supply or receiver.
FIGS. 6-8 show a modified construction that may be used when the inert sheath of the spring is relatively thick and imperforate;
FIGS. 9 and 10 are comparable to FIGS. 6-8 but show a further modification that may be used when the relatively thick inert sheath of the spring is radially perforated or apertured; I
FIGS. 11-13 show a further modification in which the closure for the distal end of the spring is rigidly affixed to the distal end of the wire stylette while being unattached to the distal end of the spring; and
FIG. 14 is a further modification, based primarily upon FIGS. llI-13,'and showing one manner of necking downthe sheathing to limit the distal elongation of the spring and to provide a distal stop or abutment for the closure.
Referring to the drawings in detail the invention, as
illustrated, may be embodied in any diagnostic, surgical or treating device that includes (see FIGS. 1 and 2) an elongated body generally indicated 5 preferably formed from a helically wound spring having its proximal coils 6 in contact with each other and having its distal coils 7 normally separated to function as a valveforming compression spring distal extension of the body.
The distal tip of the separated coils 7 is sealed by a solid closure 8 welded or otherwise permanently affixed thereto and a flexible wire sytlette 9 extends through the lumen of the spring body and has its distal end affixed to the closure 8 and is sufficiently long that its proximal end projects proximally beyond the proximal end of the spring body 5 so that tension can be applied thereto when desired in. order to axially compact the coils 7 into mutual contact, thus shutting off any fluid flow therebetween into or out of the body lumen. Obviously, release of tension on the stylette 9 will permit the coils 7 to again separate for resumption of fluid flow therebetween.
Recongnizing that such devices generally require the use of an inert smooth outer coating or sheathing such as that provided by a polyfluoroethylene compound, a thin flexible coating or sheathing 10 is applied to the full length of the device and is provided at its distal end with a plurality of radial slots or apertures 11 (see FIG. 1) aligned with the spaces between the normally separated coils 7. When tension is applied to the stylette 9 to close the valve tip, the coating 10 simply compacts into bellows-folds or pleats without preventing the spring coils 7 from being brought into mutual contact for valve closing purposes.
FIGS. 3 and 4 show a modification by which the principles of this invention may be applied to tapered distal tip if desired. Here, the normally separated coils 7 are of progressively decreasing radii in order to provide the desired taper and preferably the varying radii should be such as to permit the successive coils to become seated one upon another when the valve is in its closed position as indicated in FIG. 4.
However, if for any reason it should be desired to have the valve substantially flat in its closed position, the progressively decreasing radii of the coils 7 can be reduced further so that the coils can become nested in radial contact within a single plane, rather than becoming seated one upon another as in FIG. 4.
FIG. 5 shows a typical complete device in which the proximal end is provided with a fitting 12 having an angled fluid connector 13 and a proximal end 14 through which the proximal end of the stylette 9 passes for adjustable positioning as by a clamp 15.
Although it is believed that the nature of this invention will have become fully understood from the foregoing description, certain modifications thereof may be employed in the event that the sheathing or coating 10 should be too thick to permit its axial compaction by manipulation of the stylette 9.
For example, FIGS. 6-8 show a modification in which an imperforate relatively thick sheathing or coating 16 is bonded to the proximal coils 6 but is not bonded to the normally separated distal coils 7 so that the distal coils may partake of axial sliding movement within the distal end portion of the sheathing 16. FIG. 6 shows the normally open status of the distal end parts; FIG. 7 shows the distal end valve as it would be closed during insertion into a vessel; and FIG. 8 shows the distal end valve in a wider open position that may be achieved during retention in the vessel by pushing the stylette in a distal direction beyond the position normally achieved solely by the natural spring expansion of the distal coils 7. The distal end valve may of course be closed at any time to the condition shown in FIG. 7 by proximal manipulation of the stylette 9. In this modification fluid flows into or out of the lumen of the device through the passages between the distal coils 7 whenever those coils are in their separated condition and project beyond the distal end of the sheathing.
As a further example of such maodifications, FIGS. 9 and 10 illustrate a different structure in which, as in the case of FIGS. 6-18, the sheathing or coating 16 is relatively thick but entirely surrounds the full length of the normally separated distal coils 7. Here, the sheathing 16 is provided with a plurality of radial slots or apertures 17 through which fluid flow into or out of the lumen of the device may occur, depending upon the open or closed condition of the distal end valve.
The normal condition of the distal end elements is shown in FIG. 9 in which the valve-forming portions thereof are open and the closure 8 forms a sliding seal at the distal end of the sheath 16. FIG. 10 illustrates the relative positions of the parts when the distal end valve is closed.
A further modification of that illustrated in FIGS. 9 and 10 is shown in FIGS. 11-13. Here, the closure element 8, while still being affixed to the distal end of the stylette 9, is free from attachment to the distal end of the coils 7 so that it may partake of relative motion with respect thereto and serve as a valve supplemental to that defined by the normally separated distal coils 7.
Thus, FIG. 11 shows the normal condition of the device with the normally separated valve-forming distal coils 7 retained within the distal end portion of the sheathing 16 and the closure 8 seated on the coils at the distal end of the sheathing. In this condition fluid flow may occur into or out of the lumen of the device through the sheath apertures 17 and the passages between the coils 7. Additional flow capacity may be provided, as shown in FIG. 12, by distally advancing the closure 8. FIG. 13 shows the valve of this modification in its closed position, which essentially is the same as in FIG. 10.
It also should be mentioned that the supplemental valve function of the closure 8 as shown in FIGS. 11-13 can readily be adapted to a sole direct or primary valve function simply by eliminating the valve-forming distal end spring coils 7 and having the closure seatable upon the distal end of the proximal coils 6. In such event the sheathing would be imperforate and the normal configuration would be somewhat similar to that shown in FIG. 7 and the open valve configuration would be somewaht similar to that shown in FIG. 12.
FIG. 14 shows a further modification, similar to that shown in FIGS. 11-13, in which the sheathing 16 may be necked down as at 18 to provide an abutment for preventing abnormal axial elongation of the distal coils 7 and in which the sheathing 16 may be extended beyond the distal end of the coils 7 to define a generally spherical retention cage 19 for the closure 8 which thus still can perform its supplemental valve function while still being restrained from axial movement beyond the distal tip of the sheathing extension.
A further modification (not shown) could be a variation of that shown in FIGS. 9 and 10. Here, the normally separated coils 7 would be interposed between the mutually contacting body coils 6 and a similarly coiled body distal tip, so that the similarly coiled distal tip, in effect, could serve as a sliding plug within the sheathing 16. Of course, in such a further modification the radial apertures 17 would be relatively relocated in order still to register with the spaces between the separated coils 7.
The principles of this invention are equally applicable to those currently used types of intravenous feeding tubes or catheters formed from plastic tubing, in which event it is only necessary to fit the distal end thereof with a normally open coiled spring valve as heretofore described and to include a proximally controlled sytlette within the lumen.
It is of course to be understood that variations in arrangements and proportions of parts may be made within the scope of the appended claims.
1. A flexible catheter-like device, including a flexible inner lumen-defining body having proximal and distal ends, a helically would spring defining an open end distal extension of said inner body and having proximal and distal ends, said distal extension being formed with the coils thereof normally separated whereby to provide normally open passages therebetween for fluid flow into or out of the lumen of said inner body, said inner body being enclosed within an outer smooth flexible sheathing, firmly bonded thereto and formed from an inert plastic material, said sheathing extending distally beyond the distal end of said inner body to define a hollow tip for containing said spring-defined distal extension, means for closing the distal end of said distal extension, and a stylette passing through the lumen of said inner body and having its distal end affixed to said distal end closing means and having its proximal end extending proximally beyond the proximal end of said inner body for proximally contracting said distal extension to move the coils thereof into mutual contact, whereby to close the normally open passages therebetween.
2. The device of claim 1 in which said inner body is formed from a helically wound spring with the helices thereof in contact with each other and in which said distal end extension is formed as a continuation of said body spring.
3. The device of claim 1 in which the distally extending portion of said outer sheathing is coextensive in length with the said distal extension of said inner body and is firmly bonded to the separated coils thereof, said distally extending portion of said outer sheathing being provided with a plurality of radial apertures in register with corresponding passages between said normally separated coils.
4. The device of claim 1 in which the distally extending portion of said outer sheathing has a length sufficient to define a cavity for retaining said spring-defined distal extension when said distal extension is proximally contracted to its mutual coil-contacting condition, said distally extending portion of said outer sheathing being unbonded to said spring-defined distal extension whereby to permit the coils of said distal extension to partake of axial movement relative thereto, said distal end closing means being sealed to the distal coil of said distal end extension.
5. The device of claim 1 in which the distally extending portion of said outer sheathing is coextensive in length with the said distal extension of said inner body but is unbonded thereto whereby to permit the coils of said distal extension to partake of axial movement relative thereto, said distally extending portion of said outer sheathing being provided with a plurality of radial apertures in register with corresponding passages between said normally separated coils, said distal end closing means being sealed to the distal coil of said distal end extension.
6. The device of claim 1 in which the distally extending portion of said outer sheathing is coextensive in length with the said distal extension of said inner body, but is unbonded thereto whereby to permit the coils of said distal extension to partake of axial movement relative thereto, said distally extending portion of said outer sheathing being provided with a plurality of radial apertures in register with corresponding passages between said normally separated coils, said distal end closing means being located distally of the distal end of said distal end extension and being axially movable relative thereto, whereby to serve as a valve supplementary to that defined by the coils of said distal end extension.
7. The device of claim 6 in which the distally extending portion of said outer sheathing additionally if provided with a distal extension having a proximal end and a distal end portion, the proximal end of said sheathing distal extension being necked down to restrain said distal end spring extension against abnormal axial elongation, said distal end portion of said sheathing extension being configured to define a generally spherical cage for freely retaining said distal end closing means therein.
8. The device of claim 1 additionally including means operably associated with the proximal end thereof for releasably retaining said stylette in a proximally retracted position such as to maintain said distal spring extension in its proximally contracted condition.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US342275 *||16 Feb 1880||18 May 1886||Governor-valve|
|US396754 *||5 Oct 1888||29 Jan 1889||Catheter|
|US399540 *||2 Aug 1888||12 Mar 1889||John ellwood lee|
|US623022 *||30 Mar 1898||11 Apr 1899||johnson|
|US812020 *||4 Nov 1905||6 Feb 1906||Max Huncke Chemical Co||Embalming-catheter.|
|US2189129 *||9 Mar 1937||6 Feb 1940||Chalon E Bridwell||Valve|
|US3757768 *||7 Apr 1972||11 Sep 1973||Medical Evaluation Devices And||Manipulable spring guide-catheter and tube for intravenous feeding|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3973556 *||20 Jun 1975||10 Aug 1976||Lake Region Manufacturing Company, Inc.||Smoothened coil spring wire guide|
|US4368730 *||12 Feb 1981||18 Jan 1983||Nigel Sharrock||Intravenous catheter|
|US4456017 *||22 Nov 1982||26 Jun 1984||Cordis Corporation||Coil spring guide with deflectable tip|
|US4548206 *||21 Jul 1983||22 Oct 1985||Cook, Incorporated||Catheter wire guide with movable mandril|
|US4634432 *||13 May 1985||6 Jan 1987||Nuri Kocak||Introducer sheath assembly|
|US4757827 *||17 Feb 1987||19 Jul 1988||Versaflex Delivery Systems Inc.||Steerable guidewire with deflectable tip|
|US4773432 *||9 Feb 1987||27 Sep 1988||Schneider-Shiley (Usa) Inc.||Bail-out catheter|
|US4787399 *||1 Jul 1987||29 Nov 1988||Sarcem S.A.||Remote controlled catheter guide|
|US4813434 *||31 Mar 1988||21 Mar 1989||Medtronic Versaflex, Inc.||Steerable guidewire with deflectable tip|
|US4815478 *||31 Mar 1988||28 Mar 1989||Medtronic Versaflex, Inc.||Steerable guidewire with deflectable tip|
|US4830013 *||30 Jan 1987||16 May 1989||Minnesota Mining And Manufacturing Co.||Intravascular blood parameter measurement system|
|US4834709 *||19 Jan 1988||30 May 1989||Sherwood Medical Company||Preformable catheter|
|US4841976 *||17 Dec 1987||27 Jun 1989||Schneider-Shiley (Usa) Inc.||Steerable catheter guide|
|US4895168 *||21 Jan 1988||23 Jan 1990||Schneider (Usa) Inc., A Pfizer Company||Guidewire with movable core and external tubular safety cover|
|US4932419 *||21 Mar 1988||12 Jun 1990||Boston Scientific Corporation||Multi-filar, cross-wound coil for medical devices|
|US4934369 *||23 Mar 1989||19 Jun 1990||Minnesota Mining And Manufacturing Company||Intravascular blood parameter measurement system|
|US4943289 *||9 Jun 1989||24 Jul 1990||Cook Pacemaker Corporation||Apparatus for removing an elongated structure implanted in biological tissue|
|US4951669 *||8 Aug 1988||28 Aug 1990||Minnesota Mining And Manufacturing Company||Blood parameter measurement system|
|US4984581 *||12 Oct 1988||15 Jan 1991||Flexmedics Corporation||Flexible guide having two-way shape memory alloy|
|US4988347 *||9 Nov 1988||29 Jan 1991||Cook Pacemaker Corporation||Method and apparatus for separating a coiled structure from biological tissue|
|US4989606 *||8 Aug 1988||5 Feb 1991||Minnesota Mining And Manufactoring Company||Intravascular blood gas sensing system|
|US5013310 *||17 Jan 1989||7 May 1991||Cook Pacemaker Corporation||Method and apparatus for removing an implanted pacemaker lead|
|US5048525 *||18 Jun 1990||17 Sep 1991||Minnesota Mining And Manufacturing Company||Blood parameter measurement system with compliant element|
|US5065769 *||18 Jan 1991||19 Nov 1991||Boston Scientific Corporation||Small diameter guidewires of multi-filar, cross-wound coils|
|US5067489 *||26 Oct 1990||26 Nov 1991||Flexmedics Corporation||Flexible guide with safety tip|
|US5107852 *||2 Apr 1990||28 Apr 1992||W. L. Gore & Associates, Inc.||Catheter guidewire device having a covering of fluoropolymer tape|
|US5114342 *||1 Nov 1990||19 May 1992||Rily Young||Saliva ejector tip with integral valve|
|US5147317 *||4 Jun 1990||15 Sep 1992||C.R. Bard, Inc.||Low friction varied radiopacity guidewire|
|US5175016 *||20 Mar 1990||29 Dec 1992||Minnesota Mining And Manufacturing Company||Method for making gas sensing element|
|US5207683 *||26 Apr 1991||4 May 1993||Cook Pacemaker Corporation||Apparatus for removing an elongated structure implanted in biological tissue|
|US5250034 *||7 Aug 1991||5 Oct 1993||E-Z-Em, Inc.||Pressure responsive valve catheter|
|US5267979 *||21 Jul 1992||7 Dec 1993||E-Z-Em, Inc.||Pressure responsive valve catheter|
|US5284775 *||21 Sep 1992||8 Feb 1994||Minnesota Mining And Manufacturing Company||Gas sensing element and method for making same|
|US5304198 *||13 Nov 1992||19 Apr 1994||Target Therapeutics||Single-lumen balloon catheter having a directional valve|
|US5333620 *||8 Sep 1993||2 Aug 1994||C. R. Bard, Inc.||High performance plastic coated medical guidewire|
|US5335658 *||29 Jun 1992||9 Aug 1994||Minnesota Mining And Manufacturing Company||Intravascular blood parameter sensing system|
|US5356388 *||22 Sep 1992||18 Oct 1994||Target Therapeutics, Inc.||Perfusion catheter system|
|US5396902 *||28 May 1993||14 Mar 1995||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5421328 *||20 May 1994||6 Jun 1995||Minnesota Mining And Manufacturing Company||Intravascular blood parameter sensing system|
|US5462052 *||27 Apr 1993||31 Oct 1995||Minnesota Mining And Manufacturing Co.||Apparatus and method for use in measuring a compositional parameter of blood|
|US5507751 *||8 Jun 1994||16 Apr 1996||Cook Pacemaker Corporation||Locally flexible dilator sheath|
|US5562722 *||14 Mar 1994||8 Oct 1996||Medical Evaluation Devices & Instruments Corp.||Multiple electrode catheter|
|US5606979 *||28 May 1993||4 Mar 1997||The Microspring Company Inc.||Guide wire|
|US5607407 *||14 Aug 1995||4 Mar 1997||Tolkoff; Marc J.||Catheter assembly|
|US5632749 *||2 Apr 1993||27 May 1997||Cook Pacemaker Corporation||Apparatus for removing an elongated structure implanted in biological tissue|
|US5662119 *||21 Apr 1995||2 Sep 1997||Medtronic Inc.||Steerable stylet and manipulative handle assembly|
|US5683410 *||4 Nov 1993||4 Nov 1997||Target Therapeutics, Inc.||Single-lumen balloon catheter having a directional valve|
|US5697936 *||4 May 1995||16 Dec 1997||Cook Pacemaker Corporation||Device for removing an elongated structure implanted in biological tissue|
|US5782811 *||30 May 1996||21 Jul 1998||Target Therapeutics, Inc.||Kink-resistant braided catheter with distal side holes|
|US5853394 *||31 Dec 1996||29 Dec 1998||Tolkoff; Marc Joshua||Catheter|
|US5873842 *||26 Jun 1997||23 Feb 1999||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5997487 *||24 Jul 1997||7 Dec 1999||Micro Therapeutics, Inc.||Infusion wire having fixed core wire|
|US6004279 *||16 Jan 1996||21 Dec 1999||Boston Scientific Corporation||Medical guidewire|
|US6027461 *||11 Oct 1995||22 Feb 2000||Micro Therapeutics, Inc.||Infusion guidewire having fixed core wire and flexible radiopaque marker|
|US6063069 *||15 May 1998||16 May 2000||Micro Therapeutics Inc.||Method and apparatus for power lysis of a thrombus|
|US6096055 *||18 Jun 1997||1 Aug 2000||Target Therapuetics, Inc.||Single-lumen balloon catheter having a directional valve|
|US6102903 *||14 Dec 1995||15 Aug 2000||Medtronics, Inc.||Device and method for selectively delivering fluid into an anatomical lumen|
|US6136005 *||6 May 1997||24 Oct 2000||Cook Pacemaker Corporation||Apparatus for removing a coiled structure implanted in biological tissue, having expandable means including a laterally deflectable member|
|US6197014||11 Mar 1998||6 Mar 2001||Target Therapeutics, Inc.||Kink-resistant braided catheter with distal side holes|
|US6635027||26 Jan 2000||21 Oct 2003||Micro Therepeutics, Inc.||Method and apparatus for intramural delivery of a substance|
|US6673025||16 Nov 1999||6 Jan 2004||Advanced Cardiovascular Systems, Inc.||Polymer coated guidewire|
|US6712826||17 May 2001||30 Mar 2004||Cook Vascular Incorporated||Apparatus for removing an elongated structure implanted in biological tissue|
|US6755794||25 Apr 2001||29 Jun 2004||Synovis Life Technologies, Inc.||Adjustable stylet|
|US6926725||17 Mar 2003||9 Aug 2005||Rex Medical, L.P.||Thrombectomy device with multi-layered rotational wire|
|US7004923||21 Mar 2002||28 Feb 2006||I-Flow Corporation||Catheter for uniform delivery of medication|
|US7008535||4 Aug 2000||7 Mar 2006||Wayne State University||Apparatus for oxygenating wastewater|
|US7037316||1 Apr 2002||2 May 2006||Mcguckin Jr James F||Rotational thrombectomy device|
|US7048728 *||26 Apr 2002||23 May 2006||Witham Richard N||Noninvasive medical instrument|
|US7118539 *||26 Feb 2002||10 Oct 2006||Scimed Life Systems, Inc.||Articulating guide wire for embolic protection and methods of use|
|US7122050||4 Feb 2003||17 Oct 2006||Bard Peripheral Vascular, Inc.||Delivery mechanism for implantable stent|
|US7226441 *||23 Jun 2003||5 Jun 2007||Codman & Shurtleff, Inc.||Catheter with block-overriding system|
|US7294278||4 Nov 2005||13 Nov 2007||Wayne State University||Method for oxygenating wastewater|
|US7455646||26 Jun 2007||25 Nov 2008||Advanced Cardiovascular Systems, Inc.||Polymer coated guide wire|
|US7494474||31 Jul 2003||24 Feb 2009||Advanced Cardiovascular Systems, Inc.||Polymer coated guidewire|
|US7507246||21 Sep 2005||24 Mar 2009||Rex Medical, L.P.||Rotational thrombectomy device|
|US7540865||13 Jul 2005||2 Jun 2009||Boston Scientific Scimed, Inc.||Medical device|
|US7547302||31 Aug 2005||16 Jun 2009||I-Flow Corporation||Anti-microbial catheter|
|US7645261||12 Jan 2010||Rex Medical, L.P||Double balloon thrombectomy catheter|
|US7824345||2 Nov 2010||Boston Scientific Scimed, Inc.||Medical device with push force limiter|
|US7841994||2 Nov 2007||30 Nov 2010||Boston Scientific Scimed, Inc.||Medical device for crossing an occlusion in a vessel|
|US7850623||14 Dec 2010||Boston Scientific Scimed, Inc.||Elongate medical device with continuous reinforcement member|
|US7878984||1 Feb 2011||Boston Scientific Scimed, Inc.||Medical device for navigation through anatomy and method of making same|
|US7892186||22 Feb 2011||Heraeus Materials S.A.||Handle and articulator system and method|
|US7909801||22 Mar 2011||Rex Medical, L.P.||Double balloon thrombectomy catheter|
|US7914466||5 Aug 2003||29 Mar 2011||Precision Vascular Systems, Inc.||Medical device with collapse-resistant liner and method of making same|
|US7914467||8 Aug 2007||29 Mar 2011||Boston Scientific Scimed, Inc.||Tubular member having tapered transition for use in a medical device|
|US8022331||15 Jan 2007||20 Sep 2011||Boston Scientific Scimed, Inc.||Method of making elongated medical devices|
|US8029457 *||4 Oct 2011||Aat Catheter Technologies, Llc||Indwelling catheter with anti-clotting features|
|US8048004||1 Nov 2011||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US8048060||16 Aug 2006||1 Nov 2011||Boston Scientific Scimed, Inc.||Medical device|
|US8105246||31 Jan 2012||Boston Scientific Scimed, Inc.||Elongate medical device having enhanced torque and methods thereof|
|US8128636||9 Feb 2007||6 Mar 2012||Cook Medical Technologies Llc||Device and method for removing lumenless leads|
|US8137293||17 Nov 2009||20 Mar 2012||Boston Scientific Scimed, Inc.||Guidewires including a porous nickel-titanium alloy|
|US8182465||22 May 2012||Boston Scientific Scimed, Inc.||Medical device|
|US8231551||31 Jul 2012||Boston Scientific Scimed, Inc.||Elongate medical device with continuous reinforcement member|
|US8257279||31 Jul 2007||4 Sep 2012||Boston Scientific Scimed, Inc.||Medical device for navigation through anatomy and method of making same|
|US8343135||1 Jan 2013||Kimberly-Clark Worldwide, Inc.||Anti-microbial catheter|
|US8376961||19 Feb 2013||Boston Scientific Scimed, Inc.||Micromachined composite guidewire structure with anisotropic bending properties|
|US8377035||17 Jan 2003||19 Feb 2013||Boston Scientific Scimed, Inc.||Unbalanced reinforcement members for medical device|
|US8409114||2 Apr 2013||Boston Scientific Scimed, Inc.||Composite elongate medical device including distal tubular member|
|US8414543||23 Aug 2010||9 Apr 2013||Rex Medical, L.P.||Rotational thrombectomy wire with blocking device|
|US8435218||9 Feb 2011||7 May 2013||Rex Medical, L.P.||Double balloon thrombectomy catheter|
|US8449526||6 Dec 2007||28 May 2013||Boston Scientific Scimed, Inc.||Torqueable soft tip medical device and method of usage|
|US8535243||10 Sep 2008||17 Sep 2013||Boston Scientific Scimed, Inc.||Medical devices and tapered tubular members for use in medical devices|
|US8551020||13 Sep 2007||8 Oct 2013||Boston Scientific Scimed, Inc.||Crossing guidewire|
|US8551021||31 Mar 2011||8 Oct 2013||Boston Scientific Scimed, Inc.||Guidewire with an improved flexural rigidity profile|
|US8556914||15 Dec 2006||15 Oct 2013||Boston Scientific Scimed, Inc.||Medical device including structure for crossing an occlusion in a vessel|
|US8636716||22 May 2012||28 Jan 2014||Boston Scientific Scimed, Inc.||Medical device|
|US8652193||5 May 2006||18 Feb 2014||Angiomed Gmbh & Co. Medizintechnik Kg||Implant delivery device|
|US8784337||8 Oct 2013||22 Jul 2014||Boston Scientific Scimed, Inc.||Catheter with an improved flexural rigidity profile|
|US8795202||3 Feb 2012||5 Aug 2014||Boston Scientific Scimed, Inc.||Guidewires and methods for making and using the same|
|US8795254||10 Dec 2009||5 Aug 2014||Boston Scientific Scimed, Inc.||Medical devices with a slotted tubular member having improved stress distribution|
|US8821477||6 Aug 2007||2 Sep 2014||Boston Scientific Scimed, Inc.||Alternative micromachined structures|
|US8852266||16 Oct 2006||7 Oct 2014||Bard Peripheral Vascular, Inc.||Delivery mechanism for implantable stent|
|US8870790||31 Jul 2007||28 Oct 2014||Boston Scientific Scimed, Inc.||Medical device for navigation through anatomy and method of making same|
|US8900163||31 Jul 2007||2 Dec 2014||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US8915865||31 Jul 2007||23 Dec 2014||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US8932235||31 Jul 2007||13 Jan 2015||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US8936558||31 Jul 2007||20 Jan 2015||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US8939916||31 Jul 2007||27 Jan 2015||Precision Vascular Systems, Inc.||Medical device for navigation through anatomy and method of making same|
|US9017294||9 Mar 2013||28 Apr 2015||Rex Medical, L.P.||Rotational thrombectomy wire with blocking device|
|US9072874||11 May 2012||7 Jul 2015||Boston Scientific Scimed, Inc.||Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices|
|US9126011 *||24 Mar 2006||8 Sep 2015||Merit Medical Systems, Inc.||Anti-clotting indwelling catheter|
|US9155860||26 Aug 2011||13 Oct 2015||Merit Medical Systems, Inc.||Indwelling catheter with anti-clotting features|
|US9286673||3 Oct 2013||15 Mar 2016||Volcano Corporation||Systems for correcting distortions in a medical image and methods of use thereof|
|US9292918||13 Mar 2014||22 Mar 2016||Volcano Corporation||Methods and systems for transforming luminal images|
|US9301687||12 Mar 2014||5 Apr 2016||Volcano Corporation||System and method for OCT depth calibration|
|US9307926||2 Oct 2013||12 Apr 2016||Volcano Corporation||Automatic stent detection|
|US9324141||2 Oct 2013||26 Apr 2016||Volcano Corporation||Removal of A-scan streaking artifact|
|US20030163064 *||26 Feb 2002||28 Aug 2003||Scimed Life Systems, Inc.||Articulating guide wire for embolic protection and methods of use|
|US20030181887 *||21 Mar 2002||25 Sep 2003||Jose Castillo Deniega||Catheter for uniform delivery of medication|
|US20030191453 *||3 Apr 2003||9 Oct 2003||Velez Omar E.||Catheter assembly|
|US20030204170 *||26 Apr 2002||30 Oct 2003||Witham Richard N.||Noninvasive medical instrument|
|US20040082914 *||28 Oct 2002||29 Apr 2004||Hooper Sandra Marie||System and method for delivering medications|
|US20040260249 *||23 Jun 2003||23 Dec 2004||Codman & Shurtleff, Inc.||Catheter with block-overriding system|
|US20040260271 *||17 Jun 2004||23 Dec 2004||Huyser Richard F.||Extended fenestration catheter with internal coil and method of making the same|
|US20050192591 *||25 Feb 2005||1 Sep 2005||Lui Chun K.||Device for removing an elongated structure implanted in biological tissue|
|US20060089569 *||26 Oct 2004||27 Apr 2006||Soukup Thomas M||Articulator with adjustable stiffness distal portion|
|US20060135941 *||31 Aug 2005||22 Jun 2006||Porto James D||Anti-microbial catheter|
|US20060161119 *||15 Mar 2006||20 Jul 2006||Cathlogic, Inc.||Dysfunction resistant catheter systems and associated methods|
|US20060184105 *||15 Feb 2005||17 Aug 2006||Townsend Gregory L||Thin wall catheter and method of placing same|
|US20060258981 *||27 Apr 2005||16 Nov 2006||Tracee Eidenschink||Balloon catheter with perfusion lumen|
|US20070129682 *||2 Dec 2005||7 Jun 2007||Tracee Eidenschink||Guidewire with perfusion capability|
|US20070135733 *||9 Dec 2005||14 Jun 2007||Soukup Thomas M||Handle and articulator system and method|
|US20070191919 *||9 Feb 2007||16 Aug 2007||Cook Vascular Incorporated||Device and method for removing lumenless leads|
|US20070225661 *||27 Sep 2006||27 Sep 2007||Ash Access Technology, Inc.||Indwelling catheter with anti-clotting features|
|US20070225682 *||24 Mar 2006||27 Sep 2007||Ash Stephen R||Anti-clotting indwelling catheter|
|US20070249964 *||26 Jun 2007||25 Oct 2007||Advanced Cardiovascular Systems, Inc.||Polymer coated guide wire|
|US20080234796 *||5 May 2006||25 Sep 2008||Angiomed Gmbh & Co. Medizintechnik Kg||Implant Delivery Device|
|US20090187152 *||23 Jul 2009||L-Flow Corporation||Anti-microbial catheter|
|US20090227983 *||21 May 2009||10 Sep 2009||Boston Scientific Scimed, Inc.||Medical device|
|DE3528876A1 *||12 Aug 1985||19 Feb 1987||Schubert Werner||Guiding wire|
|DE4124606A1 *||25 Jul 1991||28 Jan 1993||Ruesch Willy Ag||Mandrel for medical instrument e.g. catheter - has external protective rubber coating contg. antithrombotic, microbicidal and fungicidal agents|
|DE4130042A1 *||10 Sep 1991||11 Mar 1993||Elky Ges Fuer Tech Entwicklung||Catheter guide wire for drainage or perfusion - has manipulatable spring coils to allow fluid passage|
|DE19934445A1 *||26 Jul 1999||1 Feb 2001||Oliver Weis||Valve control has helical spring with ends, coils and interior, two fluid chambers, thrust bearing, and passages|
|EP0145489A2 *||12 Dec 1984||19 Jun 1985||Advanced Cardiovascular Systems, Inc.||Floppy guide wire with opaque tip|
|EP0223003A2 *||11 Sep 1986||27 May 1987||B. Braun-SSC AG||Catheter|
|EP0300114A2 *||20 Jan 1988||25 Jan 1989||Hans Dr. Haindl||Catheter device|
|EP0303680A1 *||17 Feb 1988||22 Feb 1989||Versaflex Delivery Systems Inc||Steerable guidewire with deflectable tip.|
|EP0435518A1 *||13 Dec 1990||3 Jul 1991||Med Institute, Inc.||A flexible, kink-resistant catheter|
|EP0476796A1 *||13 Sep 1991||25 Mar 1992||E-Z-Em, Inc.||Pressure responsive valve catheter|
|EP0778042A2 *||2 Dec 1996||11 Jun 1997||Target Therapeutics, Inc.||Nickel-titanium, lubricious medical catheter wire|
|EP2037982A2 *||9 Jul 2007||25 Mar 2009||Ash Access Technology, Inc.||Indwelling catheter with anti-clotting features|
|WO1990005486A1 *||17 Nov 1989||31 May 1990||Boston Scientific Corporation||Small diameter guidewires|
|WO1991015251A1 *||15 Mar 1991||17 Oct 1991||W.L. Gore & Associates, Inc.||A catheter guidewire device having a covering of fluoropolymer tape|
|WO1994006500A1 *||14 Sep 1993||31 Mar 1994||Target Therapeutics, Inc.||Perfusion catheter system|
|WO1997021455A1 *||9 Dec 1996||19 Jun 1997||Medtronic, Inc.||Device and method for selectively delivering fluid into an anatomical lumen|
|WO2007064832A1 *||1 Dec 2006||7 Jun 2007||Boston Scientific Limited||Guidewire with perfusion capability|
|U.S. Classification||600/585, 604/528, 604/249|
|International Classification||A61M25/09, A61M25/00|
|11 Aug 1980||AS99||Other assignments|
Free format text: MEDICAL EVALUATION DEVICES & INSTRUMENTS CORP. 6 DIVISION ST., GLOVERSVILLE, NY * INTERNAL REVENUE SERVICE : 19800729 OTHER CASES: NONE; RELEASE OF LEVY BY IRS