US3819081A - Mailer for biological samples - Google Patents

Mailer for biological samples Download PDF

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US3819081A
US3819081A US00233164A US23316472A US3819081A US 3819081 A US3819081 A US 3819081A US 00233164 A US00233164 A US 00233164A US 23316472 A US23316472 A US 23316472A US 3819081 A US3819081 A US 3819081A
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Prior art keywords
tube
cap
strip
open end
region
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US00233164A
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H Runte
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Harre & Co A
Harre A & Co dt
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Harre & Co A
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
    • B65D41/02—Caps or cap-like covers without lines of weakness, tearing strips, tags, or like opening or removal devices
    • B65D41/04—Threaded or like caps or cap-like covers secured by rotation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D55/00—Accessories for container closures not otherwise provided for
    • B65D55/02—Locking devices; Means for discouraging or indicating unauthorised opening or removal of closure
    • B65D55/06—Deformable or tearable wires, strings, or strips; Use of seals, e.g. destructible locking pins
    • B65D55/08—Annular elements encircling container necks
    • B65D55/0818—Destructible or permanently removable bands, e.g. adhesive
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
    • B65D77/048—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical
    • B65D77/0486—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical the inner container being coaxially disposed within the outer container
    • B65D77/0493—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical the inner container being coaxially disposed within the outer container and retained at a distance of the inner side-wall of the outer container, e.g. within a bottle neck
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D13/00—Friction clutches
    • F16D13/22—Friction clutches with axially-movable clutching members
    • F16D13/38—Friction clutches with axially-movable clutching members with flat clutching surfaces, e.g. discs
    • F16D13/46—Friction clutches with axially-movable clutching members with flat clutching surfaces, e.g. discs in which two axially-movable members, of which one is attached to the driving side and the other to the driven side, are pressed from one side towards an axially-located member
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/18—Transport of container or devices
    • B01L2200/185—Long distance transport, e.g. mailing

Definitions

  • ABSTRACT A sample-receiving inner tube is threaded into an [21] Appl. No.: 233,164
  • the outer cap is UNITED STATES PATENTS stepped so that the sealing strip does not project above its surface and to form a shoulder spaced from the junction or parting line by the width of a portion of the tape as measured to the perforations to ensure proper positioning of the strip.
  • the present invention relates to a hermetically sealable package which may be sent through the mail. More particularly this invention concerns a mailable vial which is suitable for sending bacteria-sensitive materials.
  • BACKGROUND OF THE INVENTION It is often necessary to send a hermetically sealed container through the mail. To this end it is important that the container or mailer, which may be a vial, a centrifuge tube, or the like, remain tightly sealed in order to prevent the entry of any bacteria into it or even to prevent the escape of'any of its contents.
  • the container or mailer which may be a vial, a centrifuge tube, or the like, remain tightly sealed in order to prevent the entry of any bacteria into it or even to prevent the escape of'any of its contents.
  • Such a package is often used by doctors to mail samples requiring laboratory investigation to a laboratory, for patients to transmit fluid or solid specimens of body waste or sputum to a doctor or for transmission of specimens between laboratories.
  • a mailable package comprising a pair of coaxial tubes, one within the other.
  • the inner tube is open at one end and screwed into a seat formed in the base of the outer tube.
  • This outer tube is sealed by 'a cap screwed over it and formed with a seat for the closed end of the inner tube.
  • a paper strip formed with a central weakened region, advantageously a perforation line, is bonded to the outer tube and to the cap with the perforations overlying the joint line between cap and outer tube.
  • This strip is advantageously made of paper and is provided with the necessary address and postage (via a postage meter) prior to gluing over the closed container.
  • a water-insoluble glue such as chrome glue or DeKhotinsky cement, is used to prevent reuse of the container by permanently bonding the sealing strip to the package.
  • the cement is of such nature as to prevent pulling the strip from the package without a trace and thereby allowing reuse.
  • the cap has a lip threadedly engaging the outer tube.
  • Both tubes and the cap are basically cylindrical and coaxial with the cap having a small-diameter portion adjacent its rim. This small-diameter portion is of the same diameter as the outer tube and is smaller than the remainder of the cap by a radial distance equal to the thickness of the sealing strip.
  • the cap has a shoulder against which an edge of the strip can be seated for positioning the perforations at the parting line.
  • Such a tube is extremely rugged and can be quickly and easily prepared for mailing.
  • the user need merely apply the self-addressed label/sealing-strip and postage frank and drop the package in the mail. If the package has been opened in transit, this will be immediately visible on receipt since the perforations will be ruptured.
  • Such a package can be distributed to the public. for example. for tuberculosis sputum tests with preaddressed and postage paid sealing strips that only need the return address of the sender.
  • FIG. Us a longitudinal section through a tube according to the present invention.
  • FIG. '2 is a top view of a mailing-label/sealing strip usable on the tube shown in FIG. 1;
  • FIG. 3 is a section taken along line III-lll of FIG. 1.
  • the package shown in FIGS. 13 comprises an aluminum inner tube 3 of cylindrical shape with a diameter d and with a round closed end 3a and a threaded end 3b.
  • This tube 3 may be a conventional centrifuge tube.
  • An aluminum outer tube 1 of a diameter D equal to slightly less than 20' is coaxial with and surrounds'the tube 3.
  • This outer tube has a closed end la formed with a circular recess lb on the inside of which is provided a hard-rubber internally threaded cap 4.
  • the end 1b of the tube 3 is screwed into the cap 4 which itself is formed with a central nipple 40 adapted to receive a probe or the like.
  • This cap 4 is vulcanized to the interior of the tube 1 and forms a seat that makes an airtight seal with the tube 3.
  • the tube 1 has a threaded open end 1c which is formed as a threaded neck having a diameter D equal to around l.'5d.
  • This end 10 is threaded into a hardrubber cap 2 formed with a pair of coaxial cylindrical projections 2a and 2b.
  • the inner projection 2a snugly receives the closed end 3a of the tube 3 to cushion and hold this tube securely.
  • the projection 2b is internally threaded to receive the threaded end 1c of the tube 1, and is formed on its outside with a step 20 subdividing it into a cylindrical region 10 having a diameter equal to diameter D and a region of slightly greater diameter D.
  • This cap 2 can serve as a stand for the tube 3 when the tube 1 is unscrewed and removed.
  • Step 2c forms an abutment for one longitudinal edge, positioning the perforations at the separation line.
  • a sealing-strip/address label 5 is provided which is made of paper and coated with an adhesive 11 that joins with a similar adhesive coating on the reduced diameter region of projection 2b and on the portion of tube 1 immediately adjacent the threaded neck 1c.
  • This rectangular strip of paper is provided with a longitudinally weakened region in the form of perforations 6 that line up with the rim 9 of the collar 10 when the tape 5 is applied to the closed package with one of its longitudinal edges lying along the shoulder 2c.
  • This label 5 is provided with a pair of boxes 8 and 8 for the senders and receivers addresses, respectively, and with a printed-postage or franked region 7.
  • the strip 5 may also be prepared by an automatic postage meter and addressing machine. The label 5 may be so provided by the distributor.
  • this label will lie flush with the cap 2 to make a very neat package
  • the user need merely deposit the required sample in the inner tube 3, then screw this tube 3 into the cap 4, then screw the tube 1 into the cap 2 and apply the label 5.
  • the package so made may be simply dropped in the mail without the need of placing it in a mailing pouch.
  • a mailer comprising:
  • a second tube coaxially received within said firstmentioned tube and having an open end and a closed end, both of said tubes being cylindrical;
  • a second cap provided within said first tube and threadedly receiving said open end of said second tube, said first-mentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube.
  • a mailer comprising:
  • a strip adhesively secured to said tube and said cap around said joint line and provided with a region of reduced strength juxtaposed with said line.
  • said strip being provided with address and postage;
  • a second tube coaxially received within said firstmentioned tube and having an open end and a closed end, both of said tubes being cylindrical;
  • a second cap provided within said first tube and threadedly receiving said open end of said second tube, said first-mentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube, said one projection being formed with a shoulder subdividing it axially into a portion of reduced diameter adjacent said joint line and covered by said strip and a region of greater diameter, the difference between said diameters being substantially equal to twice the thickness of said strip.

Abstract

A sample-receiving inner tube is threaded into an inner cap provided in the base of an outer tube of a mailer for biological samples and the like. Another cap is screwed over the mouth of this outer tube, with this latter cap being provided with a seat for the closed end of the inner tube. An addressed and stamped (postage previously applied) sealing strip with a longitudinal perforation is applied over the joint line between the outer tube and its cap with the perforations in line with this joint line. The outer cap is stepped so that the sealing strip does not project above its surface and to form a shoulder spaced from the junction or parting line by the width of a portion of the tape as measured to the perforations to ensure proper positioning of the strip.

Description

[ 1 June 25, 1974 ,164 6/1970 Andelin et a1. 220/17 X 1 MAILER FOR BIOLOGICAL SAMPLES Inventor: Herbert Runte, Hannover, Germany [73] Assignee: Aug. Harre & Co.,
Primary Examiner-George E. Lowrance Assistant ExaminerStephen Marcus Attorney, Agent, or Firm-l(ar1 F. Ross; Herbert Dubno l-lannover-Linden, Germany Mar. 9, 1972 [22] Filed:
[57] ABSTRACT A sample-receiving inner tube is threaded into an [21] Appl. No.: 233,164
[30] Foreign Application Priority Data Mar. 12, 1971 inner cap provided in the base of an outer tube of a mailer for biological samples and the like. Another Germany................-.......;.... 7109321 cap is screwed over the mouth of this outer tube, with [52] US. 220/17, 220/8, 220/53, this latter cap being provided with a Seat for the closed end of the inner tube An addressed and stamped (postage previously applied) sealing strip 55 w ,2 M8 9 3 5 $7 B .0 2 m2 mh c .r a e S m 1 mm te hF UN 55 with a longitudinal perforation is applied over the joint 229/93; 215/95 6 line between the outer tube and its cap with the perfo- References Cited rations in line w1th this oint line. The outer cap is UNITED STATES PATENTS stepped so that the sealing strip does not project above its surface and to form a shoulder spaced from the junction or parting line by the width of a portion of the tape as measured to the perforations to ensure proper positioning of the strip.
5 Claims, 3 Drawing Figures Bozek 525751 AS x PAIENIEBJ ii .HARD RUBBER IIIIIII i FIG.
MAILER FOR BIOLOGICAL SAMPLES FIELD OF THE INVENTION The present invention relates to a hermetically sealable package which may be sent through the mail. More particularly this invention concerns a mailable vial which is suitable for sending bacteria-sensitive materials.
BACKGROUND OF THE INVENTION It is often necessary to send a hermetically sealed container through the mail. To this end it is important that the container or mailer, which may be a vial, a centrifuge tube, or the like, remain tightly sealed in order to prevent the entry of any bacteria into it or even to prevent the escape of'any of its contents. Such a package is often used by doctors to mail samples requiring laboratory investigation to a laboratory, for patients to transmit fluid or solid specimens of body waste or sputum to a doctor or for transmission of specimens between laboratories.
The customary method has been to screw the cap on the vial, and then place it in a pouch bearing the neces sary stamps and address label. In spite of the fact that such vials are not intended to be reused, disposal is never assured. In general such packages have not met with success acceptance.
OBJECTS OF THE INVENTION SUMMARY OF THE INVENTION These objects are attained according to the present invention in a mailable package comprising a pair of coaxial tubes, one within the other. The inner tube is open at one end and screwed into a seat formed in the base of the outer tube. This outer tube is sealed by 'a cap screwed over it and formed with a seat for the closed end of the inner tube. A paper strip formed with a central weakened region, advantageously a perforation line, is bonded to the outer tube and to the cap with the perforations overlying the joint line between cap and outer tube. This strip is advantageously made of paper and is provided with the necessary address and postage (via a postage meter) prior to gluing over the closed container. A water-insoluble glue, such as chrome glue or DeKhotinsky cement, is used to prevent reuse of the container by permanently bonding the sealing strip to the package. The cement is of such nature as to prevent pulling the strip from the package without a trace and thereby allowing reuse.
According to another feature of the invention the cap has a lip threadedly engaging the outer tube. Both tubes and the cap are basically cylindrical and coaxial with the cap having a small-diameter portion adjacent its rim. This small-diameter portion is of the same diameter as the outer tube and is smaller than the remainder of the cap by a radial distance equal to the thickness of the sealing strip. Thus the caphas a shoulder against which an edge of the strip can be seated for positioning the perforations at the parting line.
Such a tube is extremely rugged and can be quickly and easily prepared for mailing. The user need merely apply the self-addressed label/sealing-strip and postage frank and drop the package in the mail. If the package has been opened in transit, this will be immediately visible on receipt since the perforations will be ruptured. Such a package can be distributed to the public. for example. for tuberculosis sputum tests with preaddressed and postage paid sealing strips that only need the return address of the sender.
DESCRIPTION OF THE DRAWING The above and other objects, features, and advantages will become more readily apparent from the following description, reference being made to the accompanying drawing in which:
FIG. Us a longitudinal section through a tube according to the present invention;
FIG. '2 is a top view of a mailing-label/sealing strip usable on the tube shown in FIG. 1; and
FIG. 3 is a section taken along line III-lll of FIG. 1.
SPECIFIC DESCRIPTION The package shown in FIGS. 13 comprises an aluminum inner tube 3 of cylindrical shape with a diameter d and with a round closed end 3a and a threaded end 3b. This tube 3 may be a conventional centrifuge tube. An aluminum outer tube 1 of a diameter D equal to slightly less than 20' is coaxial with and surrounds'the tube 3. This outer tube has a closed end la formed with a circular recess lb on the inside of which is provided a hard-rubber internally threaded cap 4. The end 1b of the tube 3 is screwed into the cap 4 which itself is formed with a central nipple 40 adapted to receive a probe or the like. This cap 4 is vulcanized to the interior of the tube 1 and forms a seat that makes an airtight seal with the tube 3.
The tube 1 has a threaded open end 1c which is formed as a threaded neck having a diameter D equal to around l.'5d. This end 10 is threaded into a hardrubber cap 2 formed with a pair of coaxial cylindrical projections 2a and 2b. The inner projection 2a snugly receives the closed end 3a of the tube 3 to cushion and hold this tube securely. The projection 2b is internally threaded to receive the threaded end 1c of the tube 1, and is formed on its outside with a step 20 subdividing it into a cylindrical region 10 having a diameter equal to diameter D and a region of slightly greater diameter D. This cap 2 can serve as a stand for the tube 3 when the tube 1 is unscrewed and removed. Step 2c forms an abutment for one longitudinal edge, positioning the perforations at the separation line.
A sealing-strip/address label 5 is provided which is made of paper and coated with an adhesive 11 that joins with a similar adhesive coating on the reduced diameter region of projection 2b and on the portion of tube 1 immediately adjacent the threaded neck 1c. This rectangular strip of paper is provided with a longitudinally weakened region in the form of perforations 6 that line up with the rim 9 of the collar 10 when the tape 5 is applied to the closed package with one of its longitudinal edges lying along the shoulder 2c. This label 5 is provided with a pair of boxes 8 and 8 for the senders and receivers addresses, respectively, and with a printed-postage or franked region 7. The strip 5 may also be prepared by an automatic postage meter and addressing machine. The label 5 may be so provided by the distributor. Since the difference between diameters D and D" is equal to twice the thickness t of the label 5, this label will lie flush with the cap 2 to make a very neat package The user need merely deposit the required sample in the inner tube 3, then screw this tube 3 into the cap 4, then screw the tube 1 into the cap 2 and apply the label 5. The package so made may be simply dropped in the mail without the need of placing it in a mailing pouch.
I claim:
1. A mailer comprising:
a tube having an open end;
a cap threadable over said end and defining a joint line with said tube;
a strip adhesively secured to said tube and said cap around said joint line and provided with a region of reduced strength juxtaposed with said line, said strip being provided with address and postage;
a second tube coaxially received within said firstmentioned tube and having an open end and a closed end, both of said tubes being cylindrical; and
a second cap provided within said first tube and threadedly receiving said open end of said second tube, said first-mentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube.
2. The package defined in claim 1 wherein said strip is permanently bonded to said tube and tosaid cap.
3. The package defined in claim 2 whereinsaid cap is generally cylindrical and formed with a shoulder de fining a region of reduced diameter adjacent said joint line and a region of greater diameter.
4. The package defined in claim 3 wherein said weakened region is perforated.
5. A mailer comprising:
a tube having an open end;
a cap threadable over said end and defining a joint line with said tube;
a strip adhesively secured to said tube and said cap around said joint line and provided with a region of reduced strength juxtaposed with said line. said strip being provided with address and postage;
a second tube coaxially received within said firstmentioned tube and having an open end and a closed end, both of said tubes being cylindrical; and
a second cap provided within said first tube and threadedly receiving said open end of said second tube, said first-mentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube, said one projection being formed with a shoulder subdividing it axially into a portion of reduced diameter adjacent said joint line and covered by said strip and a region of greater diameter, the difference between said diameters being substantially equal to twice the thickness of said strip.

Claims (5)

1. A mailer comprising: a tube having an open end; a cap threadable over said end and defining a joint line with said tube; a strip adhesively secured to said tube and said cap around said joint line and provided with a region of reduced strength juxtaposed with said line, said strip being provided with address and postage; a second tube coaxially received within said first-mentioned tube and having an open end and a closed end, both of said tubes being cylindrical; and a second cap provided within said first tube and threadedly receiving said open end of said second tube, said firstmentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube.
2. The package defined in claim 1 wherein said strip is permanently bonded to said tube and to said cap.
3. The package defined in claim 2 wherein said cap is generally cylindrical and formed with a shoulder defining a region of reduced diameter adjacent said joint line and a region of greater diameter.
4. The package defined in claim 3 wherein said weakened region is perforated.
5. A mailer comprising: a tube having an open end; a cap threadable over said end and defining a joint line with said tube; a strip adhesively secured to said tube and said cap around said joint line and provided with a region of reduced strength juxtaposed with said line, said strip being provided with address and postage; a second tube coaxially received within said first-mentioned tube and having an open end and a closed end, both of said tubes being cylindrical; and a second cap provided within said first tube and threadedly receiving said open end of said second tube, said first-mentioned cap being formed with a pair of cylindrical coaxial projections, one of said projections threadedly receiving said open end of said first tube and the other of said projections snugly receiving the closed end of said second tube, said one projection being formed with a shoulder subdividing it axially into a portion of reduced diameter adjacent said joint line and covered by said strip and a region of greater diameter, the difference between said diameters being substantially equal to twice the thickness of said strip.
US00233164A 1971-03-12 1972-03-09 Mailer for biological samples Expired - Lifetime US3819081A (en)

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US20200299048A1 (en) * 2017-05-08 2020-09-24 Biomedical Regenerative Gf, Llc Device for Protecting an Inner Container
CN109313109A (en) * 2017-05-09 2019-02-05 广州非比科技有限公司 A kind of low-temperature biological preservation container
CN109313109B (en) * 2017-05-09 2021-07-06 广州非比科技有限公司 Low-temperature biological preservation container
US20210369945A1 (en) * 2018-06-25 2021-12-02 Sanofi Packaging for a medicament container
US11904132B2 (en) * 2018-06-25 2024-02-20 Sanofi Packaging for a medicament container
CN109264192A (en) * 2018-09-21 2019-01-25 泉州黄章智能科技有限公司 A kind of injection transportation and packing device
US20220097879A1 (en) * 2019-01-28 2022-03-31 Bausch + Ströbel Maschinenfabrik Ilshofen GmbH + Co. KG Method and device for sterilely enclosing a container
CN111569977A (en) * 2020-05-27 2020-08-25 衡阳师范学院 Combined centrifuge tube rack
CN111569976A (en) * 2020-05-27 2020-08-25 衡阳师范学院 Centrifuging tube strutting arrangement
CN111569977B (en) * 2020-05-27 2021-10-01 衡阳师范学院 Combined centrifuge tube rack

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Publication number Publication date
FR2128357A3 (en) 1972-10-20
FR2128357B3 (en) 1974-05-10

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