US3769490A - Transparent storage container for tc-99m eluate - Google Patents
Transparent storage container for tc-99m eluate Download PDFInfo
- Publication number
- US3769490A US3769490A US00238140A US3769490DA US3769490A US 3769490 A US3769490 A US 3769490A US 00238140 A US00238140 A US 00238140A US 3769490D A US3769490D A US 3769490DA US 3769490 A US3769490 A US 3769490A
- Authority
- US
- United States
- Prior art keywords
- container
- eluate
- transparent
- percent
- outer shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011521 glass Substances 0.000 claims abstract description 12
- XOYUVEPYBYHIFZ-UHFFFAOYSA-L diperchloryloxylead Chemical compound [Pb+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O XOYUVEPYBYHIFZ-UHFFFAOYSA-L 0.000 claims abstract description 6
- 230000002285 radioactive effect Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 5
- 229920003023 plastic Polymers 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 2
- 239000012047 saturated solution Substances 0.000 abstract description 2
- 206010073306 Exposure to radiation Diseases 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000012857 radioactive material Substances 0.000 description 2
- 238000009007 Diagnostic Kit Methods 0.000 description 1
- 230000002844 continuous effect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/015—Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers
Definitions
- a storage vessel for a reaction vial containing Tc-99m 1 1 pp N05 8,140 eluate comprises either a transparent leaded glass vessel having a thickness of from about 0.3 cm to about [52] U5.
- an object of the present invention to provide a storage vessel for a reaction vial containing radioactive material, which storage vessel, while transparent, nevertheless provides protection against exposure to radiation. Another object is to provide a syringe which, while transparent, nevertheless provides protection against exposure to radiation.
- FIG. 1 is an elevational view of one embodiment of a storage vessel, partially in section;
- FIG. 2 is an elevational view of another embodiment of a storage vessel, partially in section.
- FIG. 3 is a plan view of a syringe.
- FIG. 1 shows a storage container formed of an inner, substantially beakershaped container which is formed of glass or transparent plastic, and an outer substantially beakershaped container 11 also formed of glass or transparent plastic.
- the inner and outer containers are spaced apart a distance of from about 0.6 cm to about 2.5 cm and the intervening space is filled with a substantially saturated solution of lead perchlorate 12.
- Inner container 10 has top flange 13 which rests on the rim 14 of outer container 11.
- the reaction vial (not shown) is placed in inner container 10 and a lead cap 15 placed on the top.
- Cap 15 and lead perchlorate solu tion 12 provide protection against radiation.
- FIG. 2 shows another substantially beaker-shaped storage container 20 formed of solid, transparent leaded glass having a wall thickness of from about 0.3 cm to about 2.5 cm, preferably from about 0.6 cm to about l.2 cm, and a lead content of from about 30 percent to about 65 percent by weight. Generally, a higher lead content will be associated with a thinner wall.
- the cap in either of the above storage containers may be formed of leaded glass in which event the entire container including the cap is transparent.
- FIG. 3 is a plan view of a syringe which is otherwise conventional but which is formed of transparent leaded glass barrel 40 having a wall thickness of from about 0.6 cm to about 1.2 cm, and a lead content of from about 30 percent to about 65 percent. Generally, a higher lead content is employed with a thinner wall syringe.
- a storage container for a vessel housing radioactive eluate comprising an entirely transparent outer container shell including side and bottom walls, an entirely transparent cover memberrseated on the rim of the outer container side walls, said cover member including a central depression defining a radioactive material receiving cavity, said cavity being spaced from the interior walls of the outer shell defining a continu ous compartment therebetween, said compartment being filled with transparent radioactive shielding material.
- the container recited in claim 1 including a cap member sealing the tops of said depression and said outer shell which cap member extends across the rim of said outer shell and across said depression, said cap member being crimped about the exterior side walls of said outer shell, and said cap member is fabricated from radioactive shielding material.
- radioactive shielding material is a solution of substantially saturated lead perchlorate.
Abstract
A storage vessel for a reaction vial containing Tc-99m eluate comprises either a transparent leaded glass vessel having a thickness of from about 0.3 cm to about 2.5 cm and a lead content of from about 30 percent to about 65 percent by weight or an inner transparent receptacle which fits into an outer transparent container, the space between the inner and outer containers being filled with an aqueous, substantially saturated solution of lead perchlorate. A syringe for injecting Tc-99m eluate into a patient is formed of leaded glass as above.
Description
zifraii btie i rim v 7 V, r Umted Stat; [111 3,769,490 Czaplinski Oct. 30, 1973 [54] TRANSPARENT STORAGE CONTAINER 2,223,118 11/1940 Miller 250/108 WS FOR 99 ELUATE 3,655,985 4/1972 Brown et al 250/108 WS X [75] Inventor: Thomas V. Czaplinski, North Brunswick, NJ
[73] Assignee: E. R. Squibb & Sons, Inc.,
Princeton, NJ.
Primary Examiner-Archie R. Borchelt AttorneyLawrence S. Levinson et al.
57 ABSTRACT [22] Filed: Mar. 27, 1972 A storage vessel for a reaction vial containing Tc-99m 1 1 pp N05 8,140 eluate comprises either a transparent leaded glass vessel having a thickness of from about 0.3 cm to about [52] U5. CL. 250/108 ws 250/106 R 250/108 R 2.5 cm and a lead content of from about 30 percent to 51 int. Cl. .3 621i 5/00 65 Percent by weight inner "amparem [58] Field of Search 250/108 R, 108 ws; ceptacle which fits into an Outer transparent on- 252 m R 106 S 108 R 108 ws tainer, the space between the inner and outer containers being filled with an aqueous, substantially satu- [56] References Cited rated solution of lead perchlorate. A syringe for inject- UNITED STATES PATENTS ing Tc-99m eluate into a patient is formed of leaded glass as above. 3,673,411 6/1972 Glasser... 250/108 R 3,286,095 11/1966 Lane 250/108 WS 5 Claims, 3 Drawing Figures TRANSPARENT STORAGE CONTAINER FOR TC-99M ELUATE BACKGROUND OF THE INVENTION The present day use of the field of medicine of radioactive diagnostic kits requires that the vessel containing the radioactive substance be shielded to reduce radiation exposure to personnel administering the radioactive diagnostic test to the patient. For example, an aliquot of an eluate from a Tc-99m generator that contains from about 1 to about 100 millicuries of Tc-99m is used to prepare a radioactive formulation in a reaction vial from which it is withdrawn into a syringe for injection into the patient. While it is desirable to be able to observe the product during preparation, it has not been possible heretofore to permit this due to the necessity of providing lead shielding around both the reaction vial and the syringe. The eluate remaining in the reaction vial is then stored in' a lead container which does not permit visual observation of the amount of eluate remaining. Even when the syringe shielding and the lead container are provided (at great cost) with glass windows, it is still not possible to observe the eluate clearly.
OBJECTS OF THE INVENTION It is,'accordingly, an object of the present invention to provide a storage vessel for a reaction vial containing radioactive material, which storage vessel, while transparent, nevertheless provides protection against exposure to radiation. Another object is to provide a syringe which, while transparent, nevertheless provides protection against exposure to radiation. These and other objects of the present invention will be apparent from the following description.
BRIEF DESCRIPTION OF THE DRAWING FIG. 1 is an elevational view of one embodiment of a storage vessel, partially in section; and
FIG. 2 is an elevational view of another embodiment of a storage vessel, partially in section; and
FIG. 3 is a plan view of a syringe.
DETAILED DESCRIPTION Referring to the drawings, FIG. 1 shows a storage container formed of an inner, substantially beakershaped container which is formed of glass or transparent plastic, and an outer substantially beakershaped container 11 also formed of glass or transparent plastic. The inner and outer containers are spaced apart a distance of from about 0.6 cm to about 2.5 cm and the intervening space is filled with a substantially saturated solution of lead perchlorate 12. Inner container 10 has top flange 13 which rests on the rim 14 of outer container 11. In use the reaction vial (not shown) is placed in inner container 10 and a lead cap 15 placed on the top. Cap 15 and lead perchlorate solu tion 12 provide protection against radiation.
FIG. 2 shows another substantially beaker-shaped storage container 20 formed of solid, transparent leaded glass having a wall thickness of from about 0.3 cm to about 2.5 cm, preferably from about 0.6 cm to about l.2 cm, and a lead content of from about 30 percent to about 65 percent by weight. Generally, a higher lead content will be associated with a thinner wall. Once the reaction vial (not shown) is placed in container 20, a lead cap 21 is placed over the container.
If desired, the cap in either of the above storage containers may be formed of leaded glass in which event the entire container including the cap is transparent.
FIG. 3 is a plan view of a syringe which is otherwise conventional but which is formed of transparent leaded glass barrel 40 having a wall thickness of from about 0.6 cm to about 1.2 cm, and a lead content of from about 30 percent to about 65 percent. Generally, a higher lead content is employed with a thinner wall syringe.
What is claimed is:
1. A storage container for a vessel housing radioactive eluate comprising an entirely transparent outer container shell including side and bottom walls, an entirely transparent cover memberrseated on the rim of the outer container side walls, said cover member including a central depression defining a radioactive material receiving cavity, said cavity being spaced from the interior walls of the outer shell defining a continu ous compartment therebetween, said compartment being filled with transparent radioactive shielding material.
2. The container recited in claim 1 including a cap member sealing the tops of said depression and said outer shell which cap member extends across the rim of said outer shell and across said depression, said cap member being crimped about the exterior side walls of said outer shell, and said cap member is fabricated from radioactive shielding material.
3. The container of claim 1 wherein said radioactive shielding material is a solution of substantially saturated lead perchlorate.
4. The storage container of claim 1 wherein said cover and said outer shell are fabricated from glass having a wall thickness of 0.3 cm to 2.5 cm and a lead content of from 30 percent to 65 percent by weight.
5. The storage container of claim 1 wherein said cover and said outer shell are fabricated from a transparent plastic.
Claims (4)
- 2. The container recited in claim 1 including a cap member sealing the tops of said depression and said outer shell which cap member extends across the rim of said outer shell and across said depression, said cap member being crimped about the exterior side walls of said outer shell, and said cap member is fabricated from radioactive shielding material.
- 3. The container of claim 1 wherein said radioactive shielding material is a solution of substantially saturated lead perchlorate.
- 4. The storage container of claim 1 wherein said cover and said outer shell are fabricated from glass having a wall thickness of 0.3 cm to 2.5 cm and a lead content of from 30 percent to 65 percent by weight.
- 5. The storage container of claim 1 wherein said cover and said outer shell are fabricated from a transparent plastic.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23814072A | 1972-03-27 | 1972-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3769490A true US3769490A (en) | 1973-10-30 |
Family
ID=22896678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00238140A Expired - Lifetime US3769490A (en) | 1972-03-27 | 1972-03-27 | Transparent storage container for tc-99m eluate |
Country Status (1)
Country | Link |
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US (1) | US3769490A (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3973554A (en) * | 1975-04-24 | 1976-08-10 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Radiation safety shield for a syringe |
US4022317A (en) * | 1975-07-07 | 1977-05-10 | Kms Fusion, Inc. | Package for fragile objects |
US4122836A (en) * | 1976-09-13 | 1978-10-31 | Nuclear Pacific, Inc. | Shielding holder for radionuclid syringes |
US4185619A (en) * | 1975-12-01 | 1980-01-29 | Atomic Products Corporation | Retractable shield for syringes |
US4270052A (en) * | 1977-11-21 | 1981-05-26 | King Russell W | Radioactive gas dose computer |
EP0091175A1 (en) * | 1982-04-05 | 1983-10-12 | Machiel Nicolaas Duivelaar | Method for the safe storage of dangerous materials endangering persons and/or the environment, and appropriate shielding casing |
US4466426A (en) * | 1981-06-29 | 1984-08-21 | Blackman Seymour N | Syringe with actinic ray blocking stripe |
US5552612A (en) * | 1993-12-29 | 1996-09-03 | Nihon Medi-Physics Co., Ltd. | Transport container for transporting radiation shield member |
US6166284A (en) * | 1998-11-25 | 2000-12-26 | Mds Nordion Inc. | Container for radioisotopes |
WO2003069632A2 (en) | 2002-02-11 | 2003-08-21 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2223118A (en) * | 1938-03-25 | 1940-11-26 | Pittsburgh Plate Glass Co | Absorptive glass |
US3286095A (en) * | 1963-09-30 | 1966-11-15 | William B Lane | Zinc bromide radiation-shielding window maintained under an inert gas atmosphere |
US3655985A (en) * | 1969-05-20 | 1972-04-11 | Mallinckrodt Chemical Works | Radiation-shielding receptacle for a bottle for receiving a radioactive eluate |
US3673411A (en) * | 1970-03-03 | 1972-06-27 | Nuclear Associates Inc | Holder for radioactive material |
-
1972
- 1972-03-27 US US00238140A patent/US3769490A/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2223118A (en) * | 1938-03-25 | 1940-11-26 | Pittsburgh Plate Glass Co | Absorptive glass |
US3286095A (en) * | 1963-09-30 | 1966-11-15 | William B Lane | Zinc bromide radiation-shielding window maintained under an inert gas atmosphere |
US3655985A (en) * | 1969-05-20 | 1972-04-11 | Mallinckrodt Chemical Works | Radiation-shielding receptacle for a bottle for receiving a radioactive eluate |
US3673411A (en) * | 1970-03-03 | 1972-06-27 | Nuclear Associates Inc | Holder for radioactive material |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3973554A (en) * | 1975-04-24 | 1976-08-10 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Radiation safety shield for a syringe |
US4022317A (en) * | 1975-07-07 | 1977-05-10 | Kms Fusion, Inc. | Package for fragile objects |
US4185619A (en) * | 1975-12-01 | 1980-01-29 | Atomic Products Corporation | Retractable shield for syringes |
US4122836A (en) * | 1976-09-13 | 1978-10-31 | Nuclear Pacific, Inc. | Shielding holder for radionuclid syringes |
US4270052A (en) * | 1977-11-21 | 1981-05-26 | King Russell W | Radioactive gas dose computer |
US4466426A (en) * | 1981-06-29 | 1984-08-21 | Blackman Seymour N | Syringe with actinic ray blocking stripe |
EP0091175A1 (en) * | 1982-04-05 | 1983-10-12 | Machiel Nicolaas Duivelaar | Method for the safe storage of dangerous materials endangering persons and/or the environment, and appropriate shielding casing |
US5552612A (en) * | 1993-12-29 | 1996-09-03 | Nihon Medi-Physics Co., Ltd. | Transport container for transporting radiation shield member |
US6166284A (en) * | 1998-11-25 | 2000-12-26 | Mds Nordion Inc. | Container for radioisotopes |
WO2003069632A2 (en) | 2002-02-11 | 2003-08-21 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
WO2003069632A3 (en) * | 2002-02-11 | 2003-12-11 | Sigma Tau Ind Farmaceuti | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
AU2003209692B2 (en) * | 2002-02-11 | 2008-06-12 | Alfasigma S.P.A. | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
US20100280302A1 (en) * | 2002-02-11 | 2010-11-04 | Sigma-Tau Industrie Farmaceutiche S.P.A. | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
US7842023B2 (en) | 2002-02-11 | 2010-11-30 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
US8292869B2 (en) | 2002-02-11 | 2012-10-23 | Sigma-Tau Industrie Farmaceutiche Riunite Spa | Container for vial of radiopharmaceutical and set for its infusion in a patient or for its transfer elsewhere |
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