|Publication number||US3749086 A|
|Publication date||31 Jul 1973|
|Filing date||24 Jul 1972|
|Priority date||24 Jul 1972|
|Publication number||US 3749086 A, US 3749086A, US-A-3749086, US3749086 A, US3749086A|
|Inventors||Kline W, Roach C|
|Original Assignee||Medical Evaluation Devices & I|
|Export Citation||BiBTeX, EndNote, RefMan|
|Referenced by (117), Classifications (8), Legal Events (1)|
|External Links: USPTO, USPTO Assignment, Espacenet|
1451 July 31,1973
United States Patent 1 Kline et al.
[ SPRING GUIDE WITH FLEXIBLE DISTAL 3,552,384 1/1971 Pierie et 128/2 05 R TIP 3,547,103 12 1970 12812.05 R
Inventors: William M. Kline; Charles C. Roach,
Primary Examiner-Dalton L. Truluck Attorney-Thomas E. Tate  Assignee:
Instruments Corp., Gloversville, NY.
 ABSTRACT This invention is directed to a spring guide having an  Filed:
July 24, 1972 1 1 elongated hehcally wound sprmg body and a composite Appl. No.: 274,273
internal core constructed to enable the distal tip portion of the spring guide to flex readily without kinking while retaining its ability to return to its normally un-  US. 128/2 M, 128/205 R, 128/348,
flexed condition after having been flexed. The compos- 128/DIG. 9 A6lm 25/00 128/2 M  Int. he core comprises, proximal and distal portions in which the distal portion may be relatively more flexible than the proximal portion and corresponds in length to the distal portion of the body spring. Preferably, the distal end portion of the composite core is formed as a  Field of Search 2.05 R, DIG. 9, 4-7, 341
References Cited UNITED STATES PATENTS helical spring coiled counter to that of the body spring.
3,612,058 Ackerman...................... 128/205 R 10 Claims, 3 Drawing Figures PROXIMAL PORTION DISTAL TlP PORTION PATENIED JUL3 1 I975 FIG. 3
1 SPRING GUIDE WITH FLEXIBLE DISTAL TIP THE INVENTION This invention relates generally to new and useful improvements in spring guides of the types currently used in cardiac and vascular surgery for the proper guidance and positioning of complementing types of catheters when advanced thereover, and particularly seeks to provide a novel spring guide having a reinforced but still flexible distal tip.
Although spring guides and their complementary catheters of various constructions and various materials broadly have been known and used for some time, it has been only relatively recently recognized that, in the techniques involved, the distal tip of a spring guide must be so constructed as to remain adequately flexible while at the same time be able to avoid becoming kinked or otherwise more or less permanently deformed as the result of any unforeseen resistance to its advance through a vein or artery.
It is believed that the importance of this problem will be better understood following a brief description of the techniques involved.
Currently, such techniques involve the percutaneous insertion of a sharpened cannula into the lumen of a vein or other vessel, after which the distal end of the spring guide is inserted therethrough and the cannula withdrawn. The advance of the spring guide is controlled through fluoroscopic observation until the guide has reached the desired ultimate position of advance, and thereafter a catheter of the required type is inserted thereover and the spring guide is retracted. Obviously the distal end of the spring guide must be sufficiently flexible to follow the curvatures and branches of the vessels being catheterized without becoming subject to resistance-caused kinking while the entire less flexible proximal length of the spring guide must be sufficiently stiff as to permit its advance solely through manipulative forces applied from the proximal end. Generally, the stiffness of the spring guide for manipulative purposes has been attained through the use of a full length core wire which, unfortunately, has also added undesirable stiffness to the distal tip. Furthermore, since these types of spring guides are constructed as coil springs, the wire of the helices thereof may become broken due to inadvertent over stressings or distortions, thus requiring the presence of a so-called safety wire that extends the full length of the guide and whose only function is to prevent the separation of parts in the event of coil breakage.
However, the spring guide constructed in accordance with this invention overcomes such problems and includes the desirably flexible distal tip while retaining all of the safety and other physical characteristics now deemed to be necessary.
Therefore, an object of this invention is to provide a spring guide having a body formed as a continuous coiled spring with the helices thereof in contact with each other and including a flexible distal tip portion so constructed as to minimize the possibility of kinking when undergoing either axially applied compression loads or sharply applied angular loads.
Another object of this invention is to provide a spring guide of the character stated that includes a composite core extending the full length thereof and having a proximal portion extending from the proximal end of the spring guide to the proximal end of the distal tip portion and terminating in an inner continuous coiled spring extending along the full length of the distal tip portion.
Another object of this invention is to provide a spring guide of the character stated in which the coils of the inner spring are formed in a direction opposite to those of the spring body.
Another object of this invention is to provide a spring guide of the character stated in which the distal end of the proximal portion of the composite core is generally ball-shaped and in which the proximal end of the inner spring is affixed to the distal end of the proximal portion proximally of its ball-shaped end.
Another object of this invention is to provide a spring guide of the character stated that includes an internal safety wire extending the full length thereof and having its ends rigidly affixed to the respective ends of the body thereof.
A further object of this invention is to provide a modified form of spring guide of the character stated in which the core is formed from a capillary tube extending from the proximal end of the body to the proximal end of the distal tip portion and in which the safety wire passes through the capillary tube.
A further object of this invention is to provide a further modified form of spring guide of thecharacter stated in which the distal end of the capillary tube is provided with a coil spring extending along the full length of the distal tip portion of the body.
A further object of this invention is to provide a spring guide of the character stated that is simple in design, rugged in construction and economical to manufacture.
With these and other objects, the nature of which will become apparent, the invention will be more fully understood by reference to the drawings, the accompanying detailed description and the appended claims.
In the drawings:
FIG. 1 is an enlarged longitudinal section of a spring guide constructed in accordance with this invention;
FIG. 2 is a view similar to FIG. 1 but showing a modification of the core and distal end construction thereof; and
FIG. 3 is a view similar to FIG. 2 but showing a further modification of the core and distal end construction thereof.
Referring to the drawings in detail the invention, as illustrated, is embodied in a spring guide generally indicated 5 (see FIG. 1) that includes an elongated tubular body 6 formed from stainless wire wound as a continuous coil with the helices thereof in contact with each other. The body 6 includes a relatively long proximal portion and a relatively short distal tip portion.
A composite core is carried within the body 6 and includes a proximal wire portion 7 coextensive in length with the proximal portion of the body 6 and a distal portion 8 coextensive in length with the distal tip portion of the body. The distal end per se of the proximal core wire is hemispherically shaped (or even ball shaped) as at 9 to provide a smooth fulcrum for the distal portion 8 which comprises a continuous helical spring of opposite rotation to that of the body 6 and having an inside diameter such as to fit smoothly over the ball end of the proximal wire 7 to which it is welded or otherwise securely affixed as at 10, 10.
A safety wire 11 extends the full length of the body 6 and has its proximal portion disposed alongside the proximal wire 7 and its distal portion passing through the inner coil spring distal portion 8 of the composite core.
A smooth generally hemispherical head 12, formed by welding, brazing or soldering, closes each of the proximal and distal ends of the body 6 and also secures the proximal and distal ends of the safety wire 11 in place as well as the proximal end of the core wire 7 and the distal end of the inner extension spring 8.
A sheathing or coating 13, formed from a suitable flexible inert plastic may be, and generally is, firmly bonded to the exterior of the body 6 and extends the full length thereofin order to complete the spring guide for use.
Through the above described construction, a spring guide is provided with a distal end portion that is sufficiently flexible to permit it readily to follow the curvatures of a vessel through which it is to be inserted, without being subject to kinking, while at the same time having the capability of returning to its normally straight configuration during passage through a straight portion of the vessel. in this connection it should be noted that the ball-shaped end 9 of the proximal wire 7 of the composite core permits the extension coil spring 8 thereof to flex about its proximal end without bending around a sharp corner; and that since the coil direction of the inner spring 8 is opposite to that of the body 6, the two spring portions are complementarily opposed and tend to cause the distal tip portion of the spring guide to more naturally return to its normal straight alignment.
Comparable results may be obtained through the modifications shown in FIGS. 2 and 3 of the drawings.
In the modification shown in FIG. 2 the outer spring body 6, the end closures l2 and the outer sheath or coating are the same as previously described. However, in this modification the composite core consists of a metallic capillary or hypodermic needle type tube 14 that extends along and within the proximal portion of the body 6 and a sefety wire 15 that passes through the tube 14 and extends along the full length of the body 6. Here the safety wire 15 not only has it proximal and distal ends securely affixed to the closure beads 12, but also is welded or otherwise securely affixed to the distal end of the tube 14 as at 16.
The modification shown in FIG. 3 is similar to that of FIG. 2 except that the capillary tube 14 is provided with a helical spring distal extension 17 that has its proximal end securely affixed thereto as at 18 and its distal end securely affixed to the distal bead 12.
It will be understood from the foregoing description that, for the purposes of the mechanical or physical constructions of the spring guides of this invention, the dimensions, wire gages and relative proportions of parts need be only those necessary to properly effect such constructions. However, keeping in mind that these spring guides primarily are intended for use in the previously described surgical procedures, it also will be understood that their external diameters, regardless of overall length, must be small enough to permit the desired sizes of catheters to be advanced thereover.
1. A spring guide including an elongated body formed as a continuously wound helical spring, the helices of which are in contact with each other, and having a relatively long proximal portion and a relatively short distal tip portion; a composite core extending the full length of said body and comprising a proximal portion formed from a straight wire and a distal extension formed as a continuously wound helical spring substantially coextensive in length with the distal tip portion of said body, and means for closing the proximal and distal ends of said body and for securing the proximal and distal ends of said composite core.
2. The spring guide of claim I in which the distal end of said proximal core wire is rounded.
3. The spring guide of claim 2 additionally including a safety wire extending through the full length of said body and having its proximal and distal ends secured to the said proximal and distal end closures of said body.
4. The spring guide of claim 3 in which said safety wire passes exteriorly of said proximal core wire and interiorly of the distal extension thereof.
5. The spring guide of claim 2 in which the proximal end of said distal extension fits over the distal end of said proximal core wire and is affixed thereto proximally of the said rounded distal end thereof.
6. The spring guide of claim 1 in which the straight wire comprising the proximal portion of said composite core is replaced by a capillary tube.
7. The spring guide of claim 6 additionally including a safety wire extending along the axis of said composite core and having its proximal and distal ends secured to the said proximal and distal end closures of said body.
8. The spring guide of claim 7 in which the proximal end of said distal extension spring is affixed to the distal end of said capillary tube.
9. The spring guide of claim 1 in which said body is externally covered by an inert flexible plastic material firmly bonded thereto.
10. The spring guide of claim 6 in which said body is externally coated by an inert flexible plastic material firmly bonded thereto.
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3884230 *||27 Sep 1973||20 May 1975||Goldwyn L Wulff||Flexible needle and guard device for a hypodermic syringe|
|US3922378 *||19 Aug 1974||25 Nov 1975||Medical Evaluation Devices & I||Fluorinated hydrocarbon coating method|
|US4080706 *||4 Nov 1976||28 Mar 1978||Medrad, Inc.||Method of manufacturing catheter guidewire|
|US4368730 *||12 Feb 1981||18 Jan 1983||Nigel Sharrock||Intravenous catheter|
|US4456017 *||22 Nov 1982||26 Jun 1984||Cordis Corporation||Coil spring guide with deflectable tip|
|US4548206 *||21 Jul 1983||22 Oct 1985||Cook, Incorporated||Catheter wire guide with movable mandril|
|US4719924 *||9 Sep 1986||19 Jan 1988||C. R. Bard, Inc.||Small diameter steerable guidewire with adjustable tip|
|US4729384 *||7 Jul 1986||8 Mar 1988||Jacques Chevallier||Balloon assembly for esophageal probe|
|US4763647 *||6 Jan 1987||16 Aug 1988||C. R. Bard, Inc.||Dual coil steerable guidewire|
|US4779628 *||12 Jun 1987||25 Oct 1988||Medrad, Inc.||Guidewire assembly having moveable core and low profile safety wire|
|US4819634 *||27 Jul 1987||11 Apr 1989||Surgical Systems & Instruments||Rotary-catheter for atherectomy system|
|US4830023 *||27 Nov 1987||16 May 1989||Medi-Tech, Incorporated||Medical guidewire|
|US4886067 *||3 Jan 1989||12 Dec 1989||C. R. Bard, Inc.||Steerable guidewire with soft adjustable tip|
|US4917102 *||14 Sep 1988||17 Apr 1990||Advanced Cardiovascular Systems, Inc.||Guidewire assembly with steerable adjustable tip|
|US4922924 *||27 Apr 1989||8 May 1990||C. R. Bard, Inc.||Catheter guidewire with varying radiopacity|
|US4932419 *||21 Mar 1988||12 Jun 1990||Boston Scientific Corporation||Multi-filar, cross-wound coil for medical devices|
|US4940062 *||26 May 1988||10 Jul 1990||Advanced Cardiovascular Systems, Inc.||Guiding member with deflectable tip|
|US4951677 *||21 Mar 1988||28 Aug 1990||Prutech Research And Development Partnership Ii||Acoustic imaging catheter and the like|
|US4976680 *||7 Oct 1988||11 Dec 1990||Hayman Michael H||Apparatus for in situ radiotherapy|
|US4984581 *||12 Oct 1988||15 Jan 1991||Flexmedics Corporation||Flexible guide having two-way shape memory alloy|
|US5002041 *||7 May 1990||26 Mar 1991||Kabushiki Kaisha Machida Seisakusho||Bending device and flexible tube structure|
|US5063935 *||18 Jan 1991||12 Nov 1991||C. R. Bard, Inc.||Catheter guidewire with varying radiopacity|
|US5065769 *||18 Jan 1991||19 Nov 1991||Boston Scientific Corporation||Small diameter guidewires of multi-filar, cross-wound coils|
|US5067489 *||26 Oct 1990||26 Nov 1991||Flexmedics Corporation||Flexible guide with safety tip|
|US5084002 *||4 Aug 1988||28 Jan 1992||Omnitron International, Inc.||Ultra-thin high dose iridium source for remote afterloader|
|US5092834 *||12 Oct 1990||3 Mar 1992||Omnitron International, Inc.||Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer|
|US5125896 *||10 Oct 1990||30 Jun 1992||C. R. Bard, Inc.||Steerable electrode catheter|
|US5131406 *||19 Sep 1990||21 Jul 1992||Martin Kaltenbach||Guide for introduction of catheters into blood vessels and the like|
|US5144959 *||15 Aug 1989||8 Sep 1992||C. R. Bard, Inc.||Catheter guidewire with varying radiopacity|
|US5154705 *||24 Jul 1989||13 Oct 1992||Lake Region Manufacturing Co., Inc.||Hollow lumen cable apparatus|
|US5178158 *||29 Oct 1990||12 Jan 1993||Boston Scientific Corporation||Convertible guidewire-catheter with soft tip|
|US5213111 *||10 Jul 1991||25 May 1993||Cook Incorporated||Composite wire guide construction|
|US5345945 *||25 Dec 1993||13 Sep 1994||Baxter International Inc.||Dual coil guidewire with radiopaque distal tip|
|US5368035 *||17 Sep 1992||29 Nov 1994||Boston Scientific Corporation||Ultrasound imaging guidewire|
|US5372138 *||9 Dec 1992||13 Dec 1994||Boston Scientific Corporation||Acousting imaging catheters and the like|
|US5373619 *||14 Sep 1992||20 Dec 1994||Lake Region Manufacturing Co., Inc.||Method of making a hollow lumen cable|
|US5377690 *||9 Feb 1993||3 Jan 1995||C. R. Bard, Inc.||Guidewire with round forming wire|
|US5386828 *||17 Aug 1993||7 Feb 1995||Sims Deltec, Inc.||Guide wire apparatus with location sensing member|
|US5396902 *||28 May 1993||14 Mar 1995||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5421338 *||3 Jun 1994||6 Jun 1995||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US5497783 *||18 May 1994||12 Mar 1996||Scimed Life Systems, Inc.||Guidewire having radioscopic tip|
|US5524630 *||17 May 1995||11 Jun 1996||Crowley; Robert J.||Acoustic imaging catheter and the like|
|US5546948 *||28 Nov 1994||20 Aug 1996||Boston Scientific Corporation||Ultrasound imaging guidewire|
|US5562619 *||19 Oct 1993||8 Oct 1996||Boston Scientific Corporation||Deflectable catheter|
|US5573522 *||14 Sep 1995||12 Nov 1996||Ep Technologies, Inc.||Spring assembly for catheter|
|US5575749 *||27 Sep 1990||19 Nov 1996||Omnitron International, Inc.||Ultra-thin high dose radioactive source wire|
|US5606980 *||14 Nov 1994||4 Mar 1997||Cordis Corporation||Magnetic device for use with medical catheters and method|
|US5645065 *||11 Apr 1995||8 Jul 1997||Navion Biomedical Corporation||Catheter depth, position and orientation location system|
|US5662119 *||21 Apr 1995||2 Sep 1997||Medtronic Inc.||Steerable stylet and manipulative handle assembly|
|US5715825 *||10 Jun 1996||10 Feb 1998||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US5725570 *||29 Feb 1996||10 Mar 1998||Boston Scientific Corporation||Tubular medical endoprostheses|
|US5865800 *||8 Oct 1996||2 Feb 1999||Boston Scientific Corporation||Deflectable catheter|
|US5873842 *||26 Jun 1997||23 Feb 1999||Medtronic, Inc.||Steerable stylet and manipulative handle assembly|
|US5902291 *||29 Sep 1997||11 May 1999||Ep Technologies, Inc.||Spring assembly for catheter|
|US6056702 *||2 Oct 1998||2 May 2000||Cordis Corporation||Guidewire with outer sheath|
|US6132388 *||16 Oct 1997||17 Oct 2000||Scimed Life Systems, Inc.||Guide wire tip|
|US6165127 *||26 Sep 1997||26 Dec 2000||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US6210395||20 Oct 1997||3 Apr 2001||Lake Region Mfg., Inc.||Hollow lumen cable apparatus|
|US6277084||5 May 1997||21 Aug 2001||Boston Scientific Corporation||Ultrasonic medical device|
|US6287331||12 May 1998||11 Sep 2001||Boston Scientific Corporation||Tubular medical prosthesis|
|US6290721||21 Oct 1997||18 Sep 2001||Boston Scientific Corporation||Tubular medical endoprostheses|
|US6364840||27 Sep 2000||2 Apr 2002||Boston Scientific Corporation||Acoustic imaging catheter and the like|
|US6475167||7 Sep 2000||5 Nov 2002||Scimed Life Systems, Inc.||Guide wire tip|
|US6497709||5 May 1997||24 Dec 2002||Boston Scientific Corporation||Metal medical device|
|US6527802||23 Sep 1997||4 Mar 2003||Scimed Life Systems, Inc.||Clad composite stent|
|US6572553||4 Jan 2002||3 Jun 2003||Scimed Life Systems, Inc.||Medical imaging device|
|US6585655||31 May 2002||1 Jul 2003||Scimed Life Systems, Inc.||Medical imaging device|
|US6589227 *||26 Jan 2001||8 Jul 2003||William Cook Europe Aps||Endovascular medical device with plurality of wires|
|US6685696||9 Feb 2001||3 Feb 2004||Lake Region Manufacturing, Inc.||Hollow lumen cable apparatus|
|US7037271||27 May 2003||2 May 2006||Boston Scientific Corporation||Medical imaging device|
|US7101392||8 Aug 2001||5 Sep 2006||Boston Scientific Corporation||Tubular medical endoprostheses|
|US7946999||10 Nov 2008||24 May 2011||Scimed Life Systems, Inc.||High performance coil wire|
|US7955272||24 Sep 2001||7 Jun 2011||Boston Scientific Scimed, Inc.||High performance coil wire|
|US7976518||13 Jan 2005||12 Jul 2011||Corpak Medsystems, Inc.||Tubing assembly and signal generator placement control device and method for use with catheter guidance systems|
|US7993285||5 Nov 2002||9 Aug 2011||Boston Scientific Scimed, Inc.||Medical device having flexible distal tip|
|US8137292 *||27 Jun 2007||20 Mar 2012||Boston Scientific Scimed, Inc.||Elongated medical device for intracorporal use|
|US8187300||28 Apr 2006||29 May 2012||Tyco Healthcare Group Lp||Organopexy tool and organopexy kit|
|US8197494||8 Sep 2006||12 Jun 2012||Corpak Medsystems, Inc.||Medical device position guidance system with wireless connectivity between a noninvasive device and an invasive device|
|US8202246||4 Feb 2009||19 Jun 2012||Bridgepoint Medical, Inc.||Crossing occlusions in blood vessels|
|US8337425||5 Aug 2009||25 Dec 2012||Bridgepoint Medical, Inc.||Endovascular device with a tissue piercing distal probe and associated methods|
|US8523899 *||22 Aug 2012||3 Sep 2013||Olympus Medical Systems Corp.||Treatment device for endoscope|
|US8613713 *||28 May 2009||24 Dec 2013||Cook Medical Technologies Llc||Wire guide having variable flexibility and method of use thereof|
|US9028441||7 Sep 2012||12 May 2015||Corpak Medsystems, Inc.||Apparatus and method used with guidance system for feeding and suctioning|
|US9131956||2 Jun 2011||15 Sep 2015||Corpak Medsystems, Inc.||Tubing assembly and signal generator placement control device and method for use with catheter guidance systems|
|US20020019599 *||24 Sep 2001||14 Feb 2002||Maura Rooney||High performance coil wire|
|US20020099255 *||7 Nov 2001||25 Jul 2002||Liprie Sam F.||Afterloader apparatus|
|US20040006354 *||2 Jul 2002||8 Jan 2004||Dean Schaefer||Coaxial stretch-resistant vaso-occlusive device|
|US20040087876 *||5 Nov 2002||6 May 2004||Scimed Life Systems, Inc.||Medical device having flexible distal tip|
|US20080015471 *||27 Jun 2007||17 Jan 2008||Boston Scientific Scimed, Inc.||Elongated medical device for intracorporal use|
|US20090198256 *||28 Apr 2006||6 Aug 2009||Shigeaki Funamura||Organopexy tool and organopexy kit|
|US20090312747 *||28 May 2009||17 Dec 2009||Cook Incorporated||Wire Guide Having Variable Flexibility and Method of Use Thereof|
|US20120253321 *||22 Mar 2012||4 Oct 2012||Asahi Intecc Co., Ltd.||Guidewire|
|US20120316543 *||22 Aug 2012||13 Dec 2012||Olympus Medical Systems Corp.||Treatment device for endoscope|
|US20130152541 *||20 Dec 2012||20 Jun 2013||Asahi Intecc Co., Ltd.||Wire rope|
|DE3528876A1 *||12 Aug 1985||19 Feb 1987||Schubert Werner||Guiding wire|
|DE4124606A1 *||25 Jul 1991||28 Jan 1993||Ruesch Willy Ag||Mandrel for medical instrument e.g. catheter - has external protective rubber coating contg. antithrombotic, microbicidal and fungicidal agents|
|EP0142330A2 *||8 Nov 1984||22 May 1985||Advanced Cardiovascular Systems, Inc.||Guide wire for catheters|
|EP0142330A3 *||8 Nov 1984||23 Jul 1986||Advanced Cardiovascular System||Guide wire for catheters|
|EP0145489A2 *||12 Dec 1984||19 Jun 1985||Advanced Cardiovascular Systems, Inc.||Floppy guide wire with opaque tip|
|EP0145489A3 *||12 Dec 1984||25 Jun 1986||Advanced Cardiovascular Systems, Inc.||Floppy guide wire with opaque tip|
|EP0200919A1 *||2 Apr 1986||12 Nov 1986||ANGIOMED Aktiengesellschaft||Guide wire|
|EP0214063A1 *||4 Jul 1986||11 Mar 1987||Bazenet, Jean Pierre||Intracorporal probe and device for mounting balloons on the same|
|EP0246836A2 *||18 May 1987||25 Nov 1987||Cook Incorporated||Visceral anchor|
|EP0246836A3 *||18 May 1987||1 Jun 1988||Cook Incorporated||Visceral anchor and method for visceral wall mobilization|
|EP0255234A1 *||26 Jun 1987||3 Feb 1988||Meadox Medicals, Inc.||Steerable guidewire|
|EP0259945A2 *||12 May 1987||16 Mar 1988||C.R. Bard, Inc.||Small diameter Steerable guidewire with adjustable tip|
|EP0259945A3 *||12 May 1987||31 Aug 1988||C.R. Bard, Inc.||Small diameter steerable guidewire with adjustable tip|
|EP0274412A2 *||5 Jan 1988||13 Jul 1988||C.R. Bard, Inc.||Dual coil steerable guidewire|
|EP0274412A3 *||5 Jan 1988||8 Mar 1989||C.R. Bard, Inc.||Dual coil steerable guidewire|
|EP0318046A2 *||26 Nov 1988||31 May 1989||Boston Scientific Corporation||Medical guidewire|
|EP0386921A2 *||27 Feb 1990||12 Sep 1990||Microspring Company, Inc.||Torque transmitter|
|EP0393834A2 *||15 Mar 1990||24 Oct 1990||Samuel Shiber||Rotary catheter for atherectomy system|
|EP0397489A1 *||10 May 1990||14 Nov 1990||Kabushiki Kaisha Machida Seisakusho||Bending device and flexible tube structure|
|EP0410602A1 *||10 Jul 1990||30 Jan 1991||Lake Region Manufacturing Co. Inc.||Hollow lumen cable apparatus|
|WO1990005486A1 *||17 Nov 1989||31 May 1990||Boston Scientific Corporation||Small diameter guidewires|
|WO1990005557A1 *||17 Nov 1989||31 May 1990||Boston Scientific Corporation||Medical guidewire|
|WO1992004072A1 *||27 Aug 1991||19 Mar 1992||Baxter International Inc.||Dual coil guidewire with radiopaque distal tip|
|U.S. Classification||600/585, 604/95.1|
|International Classification||A61M25/09, A61M25/00|
|Cooperative Classification||A61M2025/09091, A61M2025/09083, A61M25/09033|
|11 Aug 1980||AS99||Other assignments|
Free format text: MEDICAL EVALUATION DEVICES & INSTRUMENTS CORP., 6 DIVISION ST. GLOVERSVILLE, NY * INTERNAL REVENUE SERVICE : 19800729 OTHER CASES: NONE; RELEASE OF LEVY BY IRS