US3625353A - Package for sterilized articles - Google Patents

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US3625353A
US3625353A US828305A US3625353DA US3625353A US 3625353 A US3625353 A US 3625353A US 828305 A US828305 A US 828305A US 3625353D A US3625353D A US 3625353DA US 3625353 A US3625353 A US 3625353A
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package
resin
adhesive agent
group
opening
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US828305A
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Ichiro Ishii
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Jintan Terumo Co Ltd
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Jintan Terumo Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2577/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks, bags
    • B65D2577/10—Container closures formed after filling
    • B65D2577/20—Container closures formed after filling by applying separate lids or covers
    • B65D2577/2041—Pull tabs
    • B65D2577/205—Pull tabs integral with the closure

Definitions

  • Weiner ABSTRACT A package particularly adapted for use in sterilizing and storing medical implements, which comprises a plastics vessel having an opening for receiving or taking out the article. and a sealing sheet made of plastics-impregnated, gas-permeable moistureproof and germproof paper, and having a hot-melt-type adhesive agent coated on the back for sealing the opening.
  • FIG. 1 A first figure.
  • FIG.2 FIG. 3
  • the present invention relates to a package particularly adapted for use in the sterilizing and storing medical implements such as an injection needle or syringe.
  • the present invention has been accomplished in view of the aforementioned circumstances and is intended to provide a package for sterilized articles which permits easy gas sterilization after sealing with a sealing sheet, is capable of effectively preventing the intrusion of germs and moisture and further enables the sealing sheet to be easily removed in a perfect and medically satisfactory condition.
  • a package for sterilized articles which comprises a plastics vessel having an opening through which a sterilized article is received or taken out, and a sealing sheet made of plastics impregnated, moistureproof and germproof paper and coated on the back with a hot-melt-type adhesive agent for sealing the opening.
  • FIG. 1 is a longitudinal view of a sealed needle package according to an embodiment of the present invention
  • FIG. 2 is a bottom view of a sealing sheet showing a lattice pattern of an adhesive agent
  • FIG. 3 is a bottom view of a sealing sheet showing an alternate pattern of an adhesive agent
  • FIG. 4 is a side elevational view of a sealed package of a syrrnge.
  • Numeral 11 represents a hypodermic needle capsule open at the top and prepared from polyethylene integrally formed into such a shape as is capable of fixing a hypodermic needle a to the inner circumferential wall surface.
  • a sealing sheet 12 To the lip of the opening of the capsule II is lightly attached a sealing sheet 12 as shown in FIG. 1. Further, the sealing sheet 12 has a peeling tab 12a extending outward as illustrated in FIG. 2 or 3, which acts as a finger grip in removing the sealing sheet 12.
  • the sealing sheet 12 is prepared from Kraft paper, high quality paper or Japanese paper impregnated with synthetic resin in suitable concentration. However, most preferable is the type particularly consisting of long fibers and having good breatheability. It is further preferred that the sealing sheet be 100 i IL in thickness from the necessity of keeping the interior of the capsule free from the intrusion of germs as well as in view of sterilizing or sealing treatment of the capsule.
  • Preferable types of synthetic resin to be impregnated in the aforementioned paper are polyacrylic ester resin, polyvinyl alcohol resin. Before impregnated in the aforesaid paper, these synthetic resins are diluted with an organic solvent such as ethyl acetate.
  • the degree of concentration in which these synthetic resins are to be impregnated is determined in consideration of the required breatheability and moistureproofness of the resultant paper, i.e. lack of the synthetic resins impregnated in the paper will result in poor moistureproofness of the resultant paper, and overimpregnation of the synthetic resins will naturally result in poor gas permeability.
  • Kraft paper 98 microns in thickness impregnated with about 7 to 15 weight percent of polyacrylic ester resin based on the Kraft paper is suitably employed.
  • said degree of concentration be such that 100 ml. of air takes an average time of from 10 to 30 seconds in passing through an area of 645.16 mm. at a pressure of 87.9 g./cm. for obtaining sufficient moistureproofness of the paper and carrying out an efficient sterilization treatment of the package.
  • the underside of the sealing sheet 12 is coated with a hotmelt-type adhesive agent 13 in a latticed form as illustrated in FIG. 2 or by wavelike lines in FIG. 3.
  • the hot-melt adhesive agent generally comprises a base resin such as polyethylene or a copolymer of polyethylene and vinyl acetate, a viscosity-imparting agent such as rosin, its derivatives, or phenolic resin, and additionally waxes and antioxidants.
  • the hot-melt-type adhesive agent having the aforesaid composition which is free from a solvent is not in the danger of a solvent being evaporated as occurring in other solvent-bearing adhesive agents, and in consequence sterilized articles are not contaminated by such solvent and no reduction in volume of the adhesive agent coated occurs, thus preventing an uneven coating of the adhesive agent.
  • the hot-melt-type adhesive agent according to the present invention has further advantage that said radiation promotes the cross-linking of the synthetic resins used to increase the bonding strength.
  • the lattice-form application, as shown in FIG. 2, or wavelike pattern as shown in FIG. 3 of the aforesaid adhesive agent ensures good breatheability of the sealing sheet I2 and the complete seal of a bonded surface and also enables the sealing sheet to be cleanly removed.
  • the surface of the sealing sheet 12 which is coated with an adhesive agent 13 is brought face to face with the open portion of the capsule l I, after the needle a is inserted into said capsule to be securely supported therein, and thereafter said open portion is sealed by thermally melting the adhesive agent 13.
  • the heating temperature generally ranges from about to about 200 C., though it is somewhat dependent on the magnitude of pressure applied on the sealing sheet 12, as well as on the length of the heating time.
  • the interior of the package thus sealed is sterilized, as in the prior art package, with a sterilizing gas, for example, a gas mixture consisting of 20 percent by volume of ethylene oxide and 80 percent by volume of carbon dioxide or by means of radiation.
  • a sterilizing gas for example, a gas mixture consisting of 20 percent by volume of ethylene oxide and 80 percent by volume of carbon dioxide or by means of radiation.
  • FIG. 4 illustrates another embodiment of the invention, wherein a hypodermic syringe is housed in a vessel 21 vacuum moulded in conformity with the shape of the syringe b and having a lengthy opening.
  • the sealing sheet 23 impregnated of a suitable amount of polyvinyl alcohol resin, and coated of a hot-melttype adhesive agent in the same manner shown in FIG. 2 or 3.
  • gas-permeable area of the sealing sheet 23 is relatively large in comparison with the volume of the vessel 21, so that sterilizing gas treatment can be conducted effectively.
  • the package according to the present invention comprises a sealing sheet formed by impregnating its base material with synthetic resin-in suitable concentration, so that it not only enables gas sterilization and seals against the intrusion of germs and moisture to be unfailingly carried out but also allows the sealing sheet to be cleanly removed with ease. Further, when the received medical implement is unsealed there is no danger of the paper fiber of the sealing sheet being scattered perchange to be attached to the syringe. This is extremely favorable from the hygienic standpoint.
  • the package of the present invention displays many other advantageous practical effects, for example, that at the time of radiation sterilization which said package also permits, the radiation promotes a cross-linking reaction among the synthetic resins involved in the adhesive agent with the resultant increase in the bonding strength.
  • a package for a sterilized article which comprises:
  • a plastic vessel having an opening through which the article is introduced or removed and a marginal flange around the periphery of the opening;
  • hot-melt type adhesive agent comprises:
  • a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate;
  • a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin, and phenolic resin.
  • a package for a sterilized article which comprises:
  • a plastic vessel having an opening through which the article is received or taken out and a marginal flange around the periphery of the opening;
  • said hot-melt type adhesive agent including a. a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate, and b. a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin and phenolic resin.

Abstract

A package particularly adapted for use in sterilizing and storing medical implements, which comprises a plastics vessel having an opening for receiving or taking out the article, and a sealing sheet made of plastics-impregnated, gas-permeable moistureproof and germproof paper, and having a hot-melt-type adhesive agent coated on the back for sealing the opening.

Description

llnited States Patent Inventor lchiro lshii Tokyo, Japan Appl. No. 828,305 1 Filed May 27, 1969 Patented Dec. 7, 1971 Assignee Jintan Terumo Co., Ltd.
Tokyo, Japan Priority Feb. 19, 1969 Japan 44/1 1778 PACKAGE FOR STERILIZED ARTICLES 4 Claims, 4 Drawing Figs.
US. Cl 206/632 R lnt.Cl B65d8l/l8 Field of Search 206/632,
[56] References Cited UNITED STATES PATENTS 3,061,087 10/1962 Scrivens et a1 206/631 3,123,210 3/1964 Hermanson et al. 206/632 3,229,813 1/1966 Crowe, Jr. et a1. 206/632 3,247,957 4/1966 Kemble 206/632 3,410,395 11/1968 Sellers 206/632 3,435,948 4/1969 Kaganov et a1. 206/632 3,485,239 12/1969 Vanderbeck 206/43 Primary ExaminerWilliam T. Dixson, .lr, Attorney-Irving M. Weiner ABSTRACT: A package particularly adapted for use in sterilizing and storing medical implements, which comprises a plastics vessel having an opening for receiving or taking out the article. and a sealing sheet made of plastics-impregnated, gas-permeable moistureproof and germproof paper, and having a hot-melt-type adhesive agent coated on the back for sealing the opening.
PATENYTED um 7:92!
FIG.
FIG.2 FIG. 3
FIG. 4
PACKAGE FOR STERILIZED ARTICLES The present invention relates to a package particularly adapted for use in the sterilizing and storing medical implements such as an injection needle or syringe.
I-Ieretofore, there has been known a handy package for a medical implement wherein said implement received in a plastics capsule assuming a suitable size to match itsshape is sterilized before or after the capsuled implement is hermetically sealed with a sealing sheet similarly made of plastics material, so as to save the trouble of performing any extra sterilizing treatment at the time of use or to render it immediately available in an emergency. With the prior art package, however, a sealing sheet for heat sealing a vessel containing an implement is made of the same plastics material as the vessel, and liable to adhere to the vessel so strongly that when the vessel is to be unsealed, the sealing sheet is easily broken and fails to be satisfactorily opened. Further, it is difficult to carry out gas sterilization once the vessel has been sealed with the sealing sheet. Accordingly, the prior art package is accompanied with various inconveniences as described above.
The present invention has been accomplished in view of the aforementioned circumstances and is intended to provide a package for sterilized articles which permits easy gas sterilization after sealing with a sealing sheet, is capable of effectively preventing the intrusion of germs and moisture and further enables the sealing sheet to be easily removed in a perfect and medically satisfactory condition.
According to the present invention, there is provided a package for sterilized articles which comprises a plastics vessel having an opening through which a sterilized article is received or taken out, and a sealing sheet made of plastics impregnated, moistureproof and germproof paper and coated on the back with a hot-melt-type adhesive agent for sealing the opening.
The present invention can be more fully understood from the following detailed description when taken in connection with reference to the accompanying drawing, in which:
FIG. 1 is a longitudinal view of a sealed needle package according to an embodiment of the present invention;
FIG. 2 is a bottom view of a sealing sheet showing a lattice pattern of an adhesive agent;
FIG. 3 is a bottom view of a sealing sheet showing an alternate pattern of an adhesive agent; and
FIG. 4 is a side elevational view of a sealed package of a syrrnge.
There will now be described an illustrated embodiment of the present invention. Numeral 11 represents a hypodermic needle capsule open at the top and prepared from polyethylene integrally formed into such a shape as is capable of fixing a hypodermic needle a to the inner circumferential wall surface. To the lip of the opening of the capsule II is lightly attached a sealing sheet 12 as shown in FIG. 1. Further, the sealing sheet 12 has a peeling tab 12a extending outward as illustrated in FIG. 2 or 3, which acts as a finger grip in removing the sealing sheet 12.
The sealing sheet 12 is prepared from Kraft paper, high quality paper or Japanese paper impregnated with synthetic resin in suitable concentration. However, most preferable is the type particularly consisting of long fibers and having good breatheability. It is further preferred that the sealing sheet be 100 i IL in thickness from the necessity of keeping the interior of the capsule free from the intrusion of germs as well as in view of sterilizing or sealing treatment of the capsule. Preferable types of synthetic resin to be impregnated in the aforementioned paper are polyacrylic ester resin, polyvinyl alcohol resin. Before impregnated in the aforesaid paper, these synthetic resins are diluted with an organic solvent such as ethyl acetate. The degree of concentration in which these synthetic resins are to be impregnated is determined in consideration of the required breatheability and moistureproofness of the resultant paper, i.e. lack of the synthetic resins impregnated in the paper will result in poor moistureproofness of the resultant paper, and overimpregnation of the synthetic resins will naturally result in poor gas permeability. For example, Kraft paper 98 microns in thickness impregnated with about 7 to 15 weight percent of polyacrylic ester resin based on the Kraft paper is suitably employed. In terms of breatheability, it is desired that said degree of concentration be such that 100 ml. of air takes an average time of from 10 to 30 seconds in passing through an area of 645.16 mm. at a pressure of 87.9 g./cm. for obtaining sufficient moistureproofness of the paper and carrying out an efficient sterilization treatment of the package.
The underside of the sealing sheet 12 is coated with a hotmelt-type adhesive agent 13 in a latticed form as illustrated in FIG. 2 or by wavelike lines in FIG. 3. The hot-melt adhesive agent generally comprises a base resin such as polyethylene or a copolymer of polyethylene and vinyl acetate, a viscosity-imparting agent such as rosin, its derivatives, or phenolic resin, and additionally waxes and antioxidants. The hot-melt-type adhesive agent having the aforesaid composition which is free from a solvent is not in the danger of a solvent being evaporated as occurring in other solvent-bearing adhesive agents, and in consequence sterilized articles are not contaminated by such solvent and no reduction in volume of the adhesive agent coated occurs, thus preventing an uneven coating of the adhesive agent. Where sterilimtion is carried out by radiation, the hot-melt-type adhesive agent according to the present invention, has further advantage that said radiation promotes the cross-linking of the synthetic resins used to increase the bonding strength. The lattice-form application, as shown in FIG. 2, or wavelike pattern as shown in FIG. 3 of the aforesaid adhesive agent ensures good breatheability of the sealing sheet I2 and the complete seal of a bonded surface and also enables the sealing sheet to be cleanly removed.
In the package of the aforementioned arrangement, the surface of the sealing sheet 12 which is coated with an adhesive agent 13 is brought face to face with the open portion of the capsule l I, after the needle a is inserted into said capsule to be securely supported therein, and thereafter said open portion is sealed by thermally melting the adhesive agent 13. The heating temperature generally ranges from about to about 200 C., though it is somewhat dependent on the magnitude of pressure applied on the sealing sheet 12, as well as on the length of the heating time. The interior of the package thus sealed is sterilized, as in the prior art package, with a sterilizing gas, for example, a gas mixture consisting of 20 percent by volume of ethylene oxide and 80 percent by volume of carbon dioxide or by means of radiation. When the needle a is taken out for use, all the sealing sheet 12 can be cleanly peeled off with great ease by pulling the peeling tab 12a.
For example, when paper I00 microns in thickness impregnated with 10 percent solution of polyacrylic ester resin and coated in the same pattern as shown in FIG. 3 with abovementioned hot-melt-type adhesive agent was employed as a sealing sheet and heat sealed to the capsule II, the sealing sheet could not be peeled off without leaving the adhesive agent on the capsule ll, breaking no part of it and dispersing out a single piece of its filament.
FIG. 4 illustrates another embodiment of the invention, wherein a hypodermic syringe is housed in a vessel 21 vacuum moulded in conformity with the shape of the syringe b and having a lengthy opening. On the margin 22 of the opening is heat sealed the sealing sheet 23 impregnated of a suitable amount of polyvinyl alcohol resin, and coated of a hot-melttype adhesive agent in the same manner shown in FIG. 2 or 3. In this embodiment, gas-permeable area of the sealing sheet 23 is relatively large in comparison with the volume of the vessel 21, so that sterilizing gas treatment can be conducted effectively.
As mentioned above, the package according to the present invention comprises a sealing sheet formed by impregnating its base material with synthetic resin-in suitable concentration, so that it not only enables gas sterilization and seals against the intrusion of germs and moisture to be unfailingly carried out but also allows the sealing sheet to be cleanly removed with ease. Further, when the received medical implement is unsealed there is no danger of the paper fiber of the sealing sheet being scattered perchange to be attached to the syringe. This is extremely favorable from the hygienic standpoint.
The package of the present invention displays many other advantageous practical effects, for example, that at the time of radiation sterilization which said package also permits, the radiation promotes a cross-linking reaction among the synthetic resins involved in the adhesive agent with the resultant increase in the bonding strength.
What is claimed is:
1. A package for a sterilized article which comprises:
a plastic vessel having an opening through which the article is introduced or removed and a marginal flange around the periphery of the opening; and
a sealing paper sheet impregnated with a resin selected from the group consisting of polyacrylic ester resin and polyvinyl alcohol resin, so as to be moistureproof and germproof, and to have the breatheability for permitting the passage of sterilizing gas, and sparsely coated on the back with a hot-melt type adhesive agent which includes no solvent and is free from substantial reduction in volume as coated.
2. A package for a sterilized article according to claim 1, wherein said paper sheet has a breatheability such that 100 ml. of air takes from to 30 seconds in passing through an area of 645.16 mm. at a pressure of 87.9 g./cm.
3. A package for a sterilized article according to claim 1,
wherein the hot-melt type adhesive agent comprises:
a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate; and
a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin, and phenolic resin.
4. A package for a sterilized article which comprises:
a plastic vessel having an opening through which the article is received or taken out and a marginal flange around the periphery of the opening; and
a sealing paper sheet of 1001:10 microns in thickness impregnated with a resin selected from the group consisting of polyacrylic ester resin and polyvinyl alcohol resin, so as to be moistureproof and germproof, and to have a breatheability so that ml. of air takes from 10 to 30 seconds in passing through an area of 645.16 mm? at a pressure of 87.9 g./cm., and sparsely coated on the back with a hot-melt type adhesive agent;
said hot-melt type adhesive agent including a. a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate, and b. a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin and phenolic resin.
l l i

Claims (4)

1. A package for a sterilized article which comprises: a plastic vessel having an opening through which the article is introduced or removed and a marginal flange around the periphery of the opening; and a sealing paper sheet impregnated with a resin selected from the group consisting of polyacrylic ester resin and polyvinyl alcohol resin, so as to be moistureproof and germproof, and to have the breatheability for permitting the passage of sterilizing gas, and sparsely coated on the back with a hotmelt type adhesive agent which includes no solvent and is free from substantial reduction in volume as coated.
2. A package for a sterilized article according to claim 1, wherein said paper sheet has a breatheability such that 100 ml. of air takes from 10 to 30 seconds in passing through an area of 645.16 mm.2 at a pressure of 87.9 g./cm.2.
3. A package for a sterilized article according to claim 1, wherein the hot-melt type adhesive agent comprises: a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate; and a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin, and phenolic resin.
4. A package for a sterilized article which comprises: a plastic vessel having an opening through which the article is received or taken out and a marginal flange around the periphery of the opening; and a sealing paper sheet of 100 + or - 10 microns in thickness impregnated with a resin selected from the group consisting of polyacrylic ester resin and polyvinyl alcohol resin, so as to be moistureproof and germproof, and to have a breatheability so that 100 ml. of air takEs from 10 to 30 seconds in passing through an area of 645.16 mm.2 at a pressure of 87.9 g./cm.2, and sparsely coated on the back with a hot-melt type adhesive agent; said hot-melt type adhesive agent including a. a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate, and b. a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin and phenolic resin.
US828305A 1969-02-19 1969-05-27 Package for sterilized articles Expired - Lifetime US3625353A (en)

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US3854484A (en) * 1971-10-22 1974-12-17 R Jackson Endotracheal tube with liquid fillable cuff
US3923154A (en) * 1973-04-05 1975-12-02 Litton Business Systems Inc Sterilant package
US3939971A (en) * 1973-02-13 1976-02-24 Becton, Dickinson And Company Sterilant package assembly
US4828797A (en) * 1986-06-24 1989-05-09 Edward Weck Incorporated EO biological test pack
US5133454A (en) * 1990-12-06 1992-07-28 Hammer Steven G Intravenous catheter biohazard prevention packaging device
US5758775A (en) * 1996-07-22 1998-06-02 Lowe; Kim H. Protective kit for medical sharps and method for using same
US5997811A (en) * 1997-07-02 1999-12-07 Cohesion Technologies, Inc. Method for sterile syringe packaging and handling
US6026959A (en) * 1996-07-22 2000-02-22 Protec Medical Corporation Protective kit for medical sharps and method for using same
US6306254B1 (en) * 1997-04-04 2001-10-23 Fuji Photo Film Co., Ltd. Interleaf paper for photosensitive printing plate material
US20020069616A1 (en) * 1998-03-13 2002-06-13 Odell Robert B. Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
US20030121812A1 (en) * 2001-12-28 2003-07-03 Sprieck Terry L. Medical needle assemblies
WO2004002848A1 (en) * 2002-06-26 2004-01-08 E. I. Du Pont De Nemours And Company Coated sheet materials and packages made therewith
US20060032768A1 (en) * 2001-08-10 2006-02-16 Seikagaku Corporation Prefilled injector package and sterilizing or disinfecting method therefor
US20080135443A1 (en) * 2006-11-22 2008-06-12 Becton, Dickinson And Company Extravascular system packaging systems
US20100159167A1 (en) * 2008-12-23 2010-06-24 Alkor Folien Gmbh Peelable sheet for fibrous substrates
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US20120152289A1 (en) * 2010-12-21 2012-06-21 Tara Denise Smith Sterilization Container With Disposable Liner
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US20150025473A1 (en) * 2012-02-13 2015-01-22 Becton, Dickinson And Company Medical cannula package
US20190001049A1 (en) * 2015-07-28 2019-01-03 Health Robotics S.R.L. Container for Closing Caps for Syringes
CN109239223A (en) * 2018-10-12 2019-01-18 江苏力凡胶囊有限公司 A kind of test method for Capsules acetic acid

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US5197361A (en) * 1991-10-11 1993-03-30 General Electric Company Surface contouring tool
DE4428291A1 (en) * 1994-08-10 1996-02-15 Borries Horst Von Packaging for items to be sterilized
US5807343A (en) * 1996-09-30 1998-09-15 Becton Dickinson And Company Protective sealing barrier for a syringe
JP3831505B2 (en) * 1997-12-26 2006-10-11 生化学工業株式会社 Sterilization method in medical sterilization packaging
JP2000203675A (en) * 1999-01-05 2000-07-25 Terumo Corp Container for medical instrument and medical instrument
JP2006271461A (en) * 2005-03-28 2006-10-12 Terumo Corp Method of manufacturing medical instrument
JP3845110B2 (en) * 2006-01-06 2006-11-15 生化学工業株式会社 Sterilization method in medical sterilization packaging

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US3485239A (en) * 1967-11-02 1969-12-23 Becton Dickinson Co Self-contained sterile syringe

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US6026959A (en) * 1996-07-22 2000-02-22 Protec Medical Corporation Protective kit for medical sharps and method for using same
US6306254B1 (en) * 1997-04-04 2001-10-23 Fuji Photo Film Co., Ltd. Interleaf paper for photosensitive printing plate material
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US6792743B2 (en) * 1998-03-13 2004-09-21 Becton, Dickinson And Company Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
US20060032768A1 (en) * 2001-08-10 2006-02-16 Seikagaku Corporation Prefilled injector package and sterilizing or disinfecting method therefor
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US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US8444620B2 (en) 2005-02-21 2013-05-21 Biomet Biologics, Llc Method and apparatus for application of a fluid
US9028457B2 (en) 2005-02-21 2015-05-12 Biomet Biologics, Llc Method and apparatus for application of a fluid
US8042689B2 (en) 2006-11-22 2011-10-25 Becton, Dickinson And Company Extravascular system packaging systems
US20080135443A1 (en) * 2006-11-22 2008-06-12 Becton, Dickinson And Company Extravascular system packaging systems
US9211487B2 (en) 2008-04-04 2015-12-15 Biomet Biologics, Llc Sterile blood separating system
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
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US20150025473A1 (en) * 2012-02-13 2015-01-22 Becton, Dickinson And Company Medical cannula package
US9694129B2 (en) * 2012-02-13 2017-07-04 Becton, Dickinson And Company Medical cannula package
US20170266366A1 (en) * 2012-02-13 2017-09-21 Becton, Dickinson And Company Medical cannula package
US10583240B2 (en) * 2012-02-13 2020-03-10 Becton, Dickinson And Company Medical cannula package
US20190001049A1 (en) * 2015-07-28 2019-01-03 Health Robotics S.R.L. Container for Closing Caps for Syringes
US10632246B2 (en) * 2015-07-28 2020-04-28 Health Robotics S.R.L. Container for closing caps for syringes
CN109239223A (en) * 2018-10-12 2019-01-18 江苏力凡胶囊有限公司 A kind of test method for Capsules acetic acid

Also Published As

Publication number Publication date
GB1229127A (en) 1971-04-21
DE1927746A1 (en) 1970-09-03
FR2030530A5 (en) 1970-11-13
JPS4918196B1 (en) 1974-05-08
SE370867B (en) 1974-11-04

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