|
| US3995635 | 4 Nov 1974 | 7 Dec 1976 | Alza Corporation | Ocular insert |
| US4136173 | 31 Jan 1977 | 23 Jan 1979 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
| US4136177 | 31 Jan 1977 | 23 Jan 1979 | American Home Products Corp. | Xanthan gum therapeutic compositions |
| US4136178 | 31 Jan 1977 | 23 Jan 1979 | American Home Products Corp. | Locust bean gum therapeutic compositions |
| US4201210 | 28 Nov 1977 | 6 May 1980 | The United States of America as represented by the Secretary of Agriculture | Veterinary ocular ring device for sustained drug release |
| US4304226 | 3 Mar 1980 | 8 Dec 1981 | The Procter & Gamble Company | Vaginal contraceptive |
| US4959217 | 22 May 1986 | 25 Sep 1990 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| US5270051 | 15 Oct 1991 | 14 Dec 1993 | | Enzyme-orthokeratology |
| US5378475 | 21 Feb 1991 | 3 Jan 1995 | University of Kentucky Research Foundation | Sustained release drug delivery devices |
| US5472436 | 26 Jul 1994 | 5 Dec 1995 | | Ocular appliance for delivering medication |
| US5626865 | 18 Jul 1994 | 6 May 1997 | Advanced Corneal Systems, Inc. | Enzyme-orthokeratology |
| US5773019 | 27 Sep 1995 | 30 Jun 1998 | The University of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5788957 | 12 Sep 1996 | 4 Aug 1998 | Advanced Corneal Systems, Inc. | Enzyme-orthokeratology |
| US5876438 | 3 May 1996 | 2 Mar 1999 | Houston Biotechnology Incorporated | Polymeric device for the delivery of immunotoxins for the prevention of secondary cataract |
| US5902598 | 28 Aug 1997 | 11 May 1999 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
| US6063116 | 27 Jun 1997 | 16 May 2000 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US6132735 | 18 Sep 1997 | 17 Oct 2000 | ISTA Pharmaceutical, Inc. | Enzyme-orthokeratology |
| US6161544 | 28 Jan 1998 | 19 Dec 2000 | Keratoform, Inc. | Methods for accelerated orthokeratology |
| US6264971 | 4 Nov 1999 | 24 Jul 2001 | BTG International Limited | Ocular insert |
| US6303102 | 7 Sep 2000 | 16 Oct 2001 | | Cutaneously applied biodegradable tell-tale having controllable clearing time |
| US6331313 | 22 Oct 1999 | 18 Dec 2001 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| US6375972 | 26 Apr 2000 | 23 Apr 2002 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| US6413245 | 4 Oct 2000 | 2 Jul 2002 | Alcon Universal Ltd. | Sub-tenon drug delivery |
| US6413540 | 12 Sep 2000 | 2 Jul 2002 | Alcon Universal Ltd. | Drug delivery device |
| US6416777 | 19 Sep 2000 | 9 Jul 2002 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
| US6669950 | 1 Jul 2002 | 30 Dec 2003 | Alcon, Inc. | Ophthalmic drug delivery device |
| US6699493 | 28 Nov 2001 | 2 Mar 2004 | Oculex Pharmaceuticals, Inc. | Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US6756049 | 17 Dec 2001 | 29 Jun 2004 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
| US6756058 | 27 Dec 2001 | 29 Jun 2004 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with multiple agents |
| US6808719 | 1 Jul 2002 | 26 Oct 2004 | Alcon, Inc. | Drug delivery device |
| US6964781 | 27 Dec 2001 | 15 Nov 2005 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
| US6986900 | 5 Nov 2003 | 17 Jan 2006 | Alcon, Inc. | Ophthalmic drug delivery device |
| US6991808 | 23 Jan 2002 | 31 Jan 2006 | Bausch & Lomb Inc. | Process for the production of sustained release drug delivery devices |
| US7033605 | 22 Dec 2003 | 25 Apr 2006 | Allergan, Inc. | Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US7094226 | 12 Nov 2003 | 22 Aug 2006 | Alcon, Inc. | Ophthalmic drug delivery device |
| US7181287 | 24 Jul 2002 | 20 Feb 2007 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US7527621 | 16 Aug 2006 | 5 May 2009 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US7563255 | 2 May 2002 | 21 Jul 2009 | Massachusetts Eye and Ear Infirmary The Charles Stark Draper Laboratory Inc. | Implantable drug delivery device and use thereof |
| US7585517 | 20 Sep 2004 | 8 Sep 2009 | Macusight, Inc. | Transscleral delivery |
| US7621907 | 11 Mar 2003 | 24 Nov 2009 | Alcon, Inc. | Implantable drug delivery system |
| US7625582 | 20 Apr 2007 | 1 Dec 2009 | Allergan, Inc. | Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US7708711 | 12 Nov 2003 | 4 May 2010 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
| US7767223 | 11 Jul 2005 | 3 Aug 2010 | Allergan, Inc. | Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use |
| US7824704 | 15 Aug 2005 | 2 Nov 2010 | Surmodics, Inc. | Controlled release bioactive agent delivery device |
| US7846468 | 3 Nov 2008 | 7 Dec 2010 | Allergan, Inc. | Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US7943162 | 7 Dec 2006 | 17 May 2011 | Alcon, Inc. | Drug delivery device |
| US7976862 | 15 Aug 2005 | 12 Jul 2011 | Surmodics, Inc. | Controlled release bioactive agent delivery device |
| US8021680 | 29 Apr 2004 | 20 Sep 2011 | Surmodics, Inc. | Controlled release bioactive agent delivery device |
| US8034366 | 31 Oct 2007 | 11 Oct 2011 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| US8034369 | 12 Sep 2005 | 11 Oct 2011 | Surmodics, Inc. | Controlled release bioactive agent delivery device |
| US8034370 | 31 Oct 2007 | 11 Oct 2011 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| US8043628 | 31 Oct 2007 | 25 Oct 2011 | Allergan, Inc. | Methods for reducing edema |
| US8071120 | 30 Mar 2006 | 6 Dec 2011 | Allergan, Inc. | Methods for treating neovascularization and intravitreal implants |
| US8088407 | 7 Sep 2007 | 3 Jan 2012 | Allergan, Inc. | Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US8096972 | 19 Dec 2003 | 17 Jan 2012 | Johns Hopkins University | Devices for intraocular drug delivery |
| US8167855 | 25 Aug 2004 | 1 May 2012 | Vista Scientific LLC | Ocular drug delivery device |
| US8177747 | 30 Nov 2010 | 15 May 2012 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| US8222271 | 23 Mar 2007 | 17 Jul 2012 | Santen Pharmaceutical Co., Ltd. | Formulations and methods for vascular permeability-related diseases or conditions |
| US8242099 | 12 Oct 2011 | 14 Aug 2012 | Allergan, Inc. | Implants and methods for treating inflammation-mediated conditions of the eye |