|Publication number||US3270745 A|
|Publication date||6 Sep 1966|
|Filing date||11 Jun 1963|
|Priority date||11 Jun 1963|
|Publication number||US 3270745 A, US 3270745A, US-A-3270745, US3270745 A, US3270745A|
|Inventors||Charle Wood Ernest|
|Original Assignee||Peter B Samuels, Rene G Le Vaux|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (7), Referenced by (97), Classifications (14)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Sept. 6, 1966 E. c. WOOD HEMQSTATIC CLIP CONSTRUCTION'S 5 Sheets-Sheet 1 Filed June 11, 1963 INVENTOR. firnest 6'. wood ZZZ) (Z/MM W "7 @9195 Sept. 6, 1966 E. c. WOOD HEMOSTATIC CLIP CONSTRUCTIONS Filed June 11, 1963 I5 Sheets-Sheet 2.
INVENTOR. rnest C, 00001 fi LQu MMM 01.4 95
Sept. 6, 1966 E. c. WOOD 3,270,745
HEMOSTATIC CLIP CONSTRUCTIONS Fild June 11, 1963 3 Sheets-Sheet 5 FIG, 16
0 1 A\ 78 [Ceig W INVENTOR.
(fr-1165i 6 wood Wdbm aZ/MM ai'ys I r 1 mnnni United States Patent 3,270,745 HEMOSTATIC CLIP CONSTRUCTIONS Ernest Charla Wood, Los Angeles, Calif., assignor of onethird to Rene G. Le Vaux and one-third to Peter B.
Samuels Filed June 11, 1963, Ser. No. 287,133 4 Claims. (Cl. 128325) This invention relates to mechanisms for use in the strangulation of tubular members. The invention is specifically directed to mechanisms including hemostatic clips for use in the strangulation of blood vessels, especially at their open ends.
The particular application of this invention to the strangulation or closure of blood vessels will serve as an example of the illustration of the inventive concepts disclosed herein. It will be appreciated, however, that the mechanisms of this invention can be adapted for the closure of other tubular members near their open ends or at various intermediate points.
In the undertaking of a surgical operation, it is often necessary for the surgeon to sever one or more blood vessels. Since the flow of blood will interfere with the subsequent operation and since excessive loss of blood will endanger the patient, it is desirable to provide means for closing oif the severed ends of the blood vessels until the operation is completed.
Conventional techniques provide for the separate clamping of blood vessels after an incision has been made during the undertaking of an operation. After clamping of the vessels, they are each separately tied with a ligature or the like to strangula-te the vessel and to permit removal of the applied clamps. In some instances, an extremely large number of clamps must be applied, and one or two hours may be required to provide for proper closure of all the vessels whereby the operation can proceed. It will be apparent that a considerable expenditure in time from the standpoint of the surgeon and his assistants is necessary in such instances, and it will also be obvious that the delay will increase the danger to the patient undergoing the operation.
It is an object of this invention to provide improved mechanisms for use in the strangulation of blood vessels whereby the time required to close 01f the vessels is materially reduced and whereby the bleeding can be terminated without the use of an excessive combination of clamping and tieing operations.
It is a more particular object of this invention to provide improved mechanisms for the strangulation of blood vessels and the like whereby the blood vessels can be permanently sealed in a highly efficient manner to prevent bleeding during an operation and whereby the operation can proceed with a minimum loss of time and with a minimum loss of blood to thereby maintain conditions most favorable to the patient as well as to the surgeon and his assistants.
It is a specific object of this invention to provide an improved design for a hemostatic clip which is adapted to achieve the foregoing objects.
These and other objects of this invention will appear hereinafter, and for purposes of illustration but not of limitation, specific embodiments of this invention are shown in the accompanying drawings in which:
FIGURE 1 is a plan view of a hemostatic clip applicator construction;
FIGURE 2 is an enlarged fragmentary view of the jaw portion of the applicator;
FIGURE 3 is a view of one jaw portion taken about the line 33 of FIGURE 2 FIGURE 4 is an enlarged cross-sectional view taken about the line 4-4 of FIGURE 2;
FIGURE 5 is an enlarged fragmentary view taken about the line 55 of FIGURE 1 and illustrating stop means associated with the handle portions of the applicator;
FIGURE 6 is a side elevation of the applicator shown in FIGURE 1;
FIGURE 7 is an elevational view of a holding means for hemostatic clips utilized in accordance with this invention;
FIGURE 8 is an end elevation of the holding means shown in FIGURE 7;
FIGURE 9 is a view of the holding means taken about the line 9-9 of FIGURE 8;
FIGURE 10 comprises a cross-sectional illustration of the clip holding means and also illustrates a hemostatic clip construction of this invention;
FIGURE 11 comprises a cross-sectional illustration of a clip holding means and also illustrates the cooperating features of the clip applicator and hemostatic clip constructions;
FIGURE 12 is an enlarged fragmentary view illustrating the manner in which the jaw portions of the clip applicator provide for clamping of a clip;
FIGURE 13 is a perspective view of a hemostatic clip designed in accordance with the concepts of this invention;
FIGURE 14 illustrates a blood vessel having a clip clamped thereon;
FIGURE 15 illustrates a magazine holding construction adapted to hold a plurality of the clips of this invention;
FIGURE 16 is a perspective view of an alternative clip construction;
FIGURE 17 is a perspective view of the clip construction of FIGURE 16 partially closed about a tubular member;
FIGURE 18 is a perspective view of the same clip construction in the completely closed position;
FIGURE 19 is a fragmentary plan view, partly in section, of the clip construction of FIGURE 16 associated with a holder;
FIGURE 20 is a sectional elevation of the clip and holder assembly of FIGURE 19;
FIGURES 21 through 24 are detail views illustrating the clamping sequence which takes place in the use of the clip construction of FIGURE 16.
The hemostatic clip of this invention is adapted to be formed from a strip of nontoxic material whereby it can be safely .applied during an operation. The strip is formed whereby it defines a pair of arm portions with the interfaces of the arm portions being situated in an opposed relationship. These interfaces, when clamped by means to be described, engage the outer surfaces of a blood vessel for strangulating this vessel.
Protuberances are formed on the outer surfaces of the arm portions defined between clips. These protuberances serve to permit firm gripping of the clips by a clip applicator whereby the clips can be efficiently clamped by the applicator around the blood vessel. The applicator of this invent-ion includes jaw portions which define recesses for receiving the protuberances on the clip. When these protuberances are received by the jaw portions, the clip will be firmly held so that there is little tendency for the clip to be dislodged from the applicator before being applied to a blood vessel.
In order to further increase the efficiency during an oper-ation, novel holding means have been devised for the clip constructions. These holding means define slots into which the clips can be inserted. The holding means and associated clips can then be sterilized and packaged in sterile containers whereby they will be ready for use at any time. The slots defined in the holding :means are such that the jaws of the clip applicator can be received therein. Accordingly, the clips can be removed from the holding means by the clip applicator without the necessity of ever touching the clips after they have been sterilized.
The accompanying drawings will provide an illustration of examples of various mechanism characterized by the features of this invention. In FIGURES 1 through 6, there are illustrated an applicator'lt) and details of various portions thereof. A pivot 12 of the applicator divides the applicator into jaw portions 14 and handle portions 16. A leaf spring 18 is fastened to one jaw portion 16 at 19 and is movably connected to the other jaw portion.
As best shown in FIGURE 5, the end 20 of the spring 18 defines a slot 21 which is adapted to receive a hook 22 fixed to the handle portion 16. It will be apparent that when the handle portions are pressed together by means of the finger holes 23, the end 20 of the spring 18 will slide relative to its associated handle portion. When finger pressure is released, the end of the slot 21 will engage the hook 22 as illustrated in FIGURE and jaws 14.
Each of the jaws 14 define grooves 24 extending from the outer ends thereof. Recesses 26 extend downwardly from these grooves. As will appear hereinafter, the recesses and grooves provide for insertion of clips 28 into the jaws I4 and also provide for gripping of these clips when they are held by the jaws.
FIGURE 13 provides an illustration of the preferred construction of the clip 28. This clip includes a fold 30 having arm portions 32 extending angularly therefrom. Portions 34 extend from these angular portions and these portions are situated in a generally parallel relationship in respect to each other. Protuberances 36 are formed in the outer surface of these parallel portions while the opposed innerfaces 38 of these portions serve as the engaging means of the clip. These innerfaces can be serrated to provide a more desirable gripping action.
FIGURES 7 through illustrate individual holders 40 suitable for use in combination with the clips 28. These holders define slots 42 which comprise a narrow central portion 44 corresponding approximately to the thickness of the clips 28. Enlarged portions 46 of these slots are dimensioned whereby the jaws 14 of the applicator 10 can be received therein.
FIGURE illustrates a magazine construction adapted to hold a plurality of clips 28. As previously indicated, the holders for the clips are adapted to be sterilized along with the clips and then sealed in sterile packages whereby they can be held indefinitely until they are ready for use. It is preferred that the clips 28 be manufactured whereby they will firmly engage the walls of the slots 42 so that they will not become dislodged from the holders during handling.
In the use of the construction of this invention for the strangulation of a blood vessel such as shown at 56, the holders 40 or a magazine 43 is first made available. The jaws 14 of the applicator 10 are then inserted in the slots 42 as best shown in FIGURE 11. It will be noted that the grooves 24 are dimensioned approximately equal to the thickness of the clips 28. With this feature, the jaws of the applicator will be centered as they move into the slots 42, and, therefore, the protuberances 36 will naturally snap into the recesses 26. The applicator jaws can :then be withdrawn from the clip holders and the clips will remain firmly held thereby. It will be apparent that there is little tendency for the clips to fall away from the jaws .and, in this connection, there is no necessity for pressing the jaws together to hold the clips. Thus, the limited position which defines the spacing of the jaws 14 will normally be such that the jaw spacing will not greatly exceed the normal spread of the clip construction. With the provision of the protuberances 36, the clips will automatically be held by the spaced-apart jaws.
The open end of the clips can. be placed around the .severed end of a blOOd Yel 50 and when pressure is applied through the finger holes and handle portions of the applicator, the clip held by the jaws will be clamped as shown in FIGURE 14. The clips are adapted to tightly seal the blood vessel when clamped in the manner shown, and, therefore, the use of ligatures in an operation can be eliminated.
The design of the clip construction 28, which represents the preferred design, is particularly important. Thus, the provision of the parallel portions 34 serves to insure a firm gripping action by the applicator 10. These straight sections of the clip will easily slide into the grooves 24 in the jaws 14 to thereby insure receipt of the protuberances 36 into the recesses 26. When so received, the clips will remain stationary relative to the jaws since the protuberances prevent sliding movement while the grooves prevent rotary movement.
FIGURES 16 through 24 illustrate an alternative clip construction 60 and the manner in which this construction is utilized. In considering the following description, it will be noted that the applicator 10 illustrated in FIGURE 1 is also utilized in combination with this clip construction. Thus, the construction is provided with protuberanccs 62 which are adapted to be received in the recesses 26 formed in each of the jaws 14 of the applicator.
The clip construction 60 is of a generally V-shaped configuration and includes a fold 64 having arm portions 66 extending angularly therefrom. A first portion 68 extends outward-ly from one of the arms 66 and this portion terminates in an inwardly directed member 70. The member 70 forms a recess 72 in combination with the portion 68, which recess cooperates to provide a locking feature.
The other arm 66 of the clip 60 is integrally connected with the portion 74 which terminates in an outwardly extending end member 76. It will be noted that the portion 74 is substantially shorter in length than the portion 68 whereby the end member 76 is adapted to be received in the recess 72 when the clip 60 is bent about the fold 64.
FIGURES 19 and 20 illustrate a holder 78 which includes portions 80 designed in corresponding shape with the clips 60. Indentations 82 and 84 are defined in the portions 80 whereby the members 76 and 70, respectively, of each clip 60 can be held in position on the holder 78. The jaws 14 pick up the clips from the holder by engaging the protrusions 62 in the manner described with reference to the clips 28.
FIGURES 16 through 18 and 21 through 24 provide illustrations as to the configuration of the clip 60 during various stages of the clamping operation. As noted in FIGURES 17 and 22, the member 76 first clears the end of the member 70 and engages the inner surface of the portion 68. The member 76 is then adapted to be bent relative to the portion 74 as shown in FIGURE 23. A reduction in thickness of the clip at the junctures of the member 76 and the portion 74 may be provided as at 86 in order to facilitate this bending operation.
FIGURES 18 and 24 illustrate the clip after completion of the clamping operation. It will be noted that the upper jaw 14 will engage the member 70 and will bend this member down over the member 76. Accordingly, the two ends of the clip are locked together and this arrangement provides substantial insurance against the possibility of the clip sections spreading apart after application.
The clip of this invention is preferably formed of surgical metals which are nontoxic and which therefore can be tolerated within the body for indefinite periods of time. Representative of such metals are stainless steel, tantalum, and platinum. It is also contemplated that the clips be formed of less expensive materials such as plastic or of materials which are slowly absorbable in the body fluids such as collagen, gelatin, albumin, dried blood, synthetic materials and the like.
It will be understood that various changes and modifications can be made in the above described hemostatic clip construction which provides the characteristics of this invention without departing from the spirit thereof particularly as defined in the following claims.
That which is claimed is:
1. A hemost-atic clip comprising a strip of nontoxic material, said strip defining arm portions having opposed faces, a single protuberance formed on the outer surface of each of said arm portions at intermediate points along the lengths of the respective arm portions, one arm portion being longer than the other arm portion, said strip defining a V-shaped configuration which includes a central fold, said arm portions extending angularly from said fold and then bending into an approximately para1- lel relationship with said protuberances being formed on the parallel portions of said arms, an end member formed on each of said arm portions, said end members being bent toward each other and being parallel to each other, one of said end members formed on said one arm portion being directed inwardly toward the central fold of said V-shaped portion thereby defining a recess with said one arm portion, and the other end member comprising an outwardly directed end member formed on the other of said arm portions adapted to be received in said recess when said arm portions are clamped together, and wherein said end members are bent when said arm portions are clamped together with the end members being thereby pressed against each other.
2. A clip construction in accordance with claim 1 including serrations defined in the opposed faces of said parallel portions.
3. A clip construction in accordance with claim 1 in which said strip is formed of a surgical metal.
4. A clip construction in accordance with claim 1 in which said strip is formed of a material which is solely absorbable in the body fluids.
References Cited by the Examiner UNITED STATES PATENTS D. 190,787 6/ 1961 Schneider 128-346 X 1,066,025 7/1913 Lieberknecht 1349 2,123,890 7/1938 Gossrau 128325 2,123,891 7/1938 Gossrau 1349 2,758,302 8/1956 White 156 3,056,408 10/ 1962 Brown 128-325 3,086,208 4/ 196 3 Eby 1-56 RICHARD A. GAUDET, Primary Examiner.
G. MCNEILL, Assistant Examiner.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1066025 *||27 Jun 1912||1 Jul 1913||Ludwig Lieberknecht||Surgical instrument.|
|US2123890 *||28 Nov 1936||19 Jul 1938||Magnesium Dev Corp||Surgical clasp|
|US2123891 *||28 Nov 1936||19 Jul 1938||Magnesium Dev Corp||Surgical tongs|
|US2758302 *||13 Oct 1952||14 Aug 1956||Technical Oil Tool Corp||Wound clip loader package|
|US3056408 *||22 Apr 1959||2 Oct 1962||Brown Adolph M||Ligature clip|
|US3086208 *||6 Oct 1960||23 Apr 1963||Ethicon Inc||Surgical clip assembly|
|USD190787 *||1 Dec 1960||27 Jun 1961||Umbilical cord clamp|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3388369 *||18 Mar 1966||11 Jun 1968||Bell Telephone Labor Inc||Electrical connector for sheet conductors|
|US3463156 *||27 May 1965||26 Aug 1969||Rackear Bernard||Hemostatic clip and applicator|
|US3631707 *||13 Jun 1969||4 Jan 1972||Weck & Co Inc Edward||Hemostatic clip applicator|
|US3908234 *||2 Jan 1974||30 Sep 1975||Niedecker Herbert||Closure clip|
|US3926195 *||23 Apr 1973||16 Dec 1975||Bleier Waldemar||Clip, clamping jaw and assembly for the interruption of the urogenital system|
|US3954108 *||27 Aug 1974||4 May 1976||Davis Hugh J||Occlusion clip and instrument for applying same|
|US4076120 *||10 Dec 1976||28 Feb 1978||American Hospital Supply Corporation||Cartridge for holding hemostatic clips|
|US4146022 *||16 Nov 1977||27 Mar 1979||Ronald A. Johnson||Fracture fixation by cerclage utilizing cortical bone tack and pull-out tension device|
|US4166466 *||8 Oct 1976||4 Sep 1979||Jarvik Robert K||Repeating hemostatic clip applying instruments and multi-clip cartridges therefor|
|US4187712 *||4 Dec 1978||12 Feb 1980||Samuels Peter B||Hemostatic clip applicator|
|US4188953 *||5 Aug 1977||19 Feb 1980||Charles H. Klieman, M.D.||Hemostatic clip|
|US4281656 *||15 Oct 1979||4 Aug 1981||Rocket Of London Limited||Hulka-type clip applicator|
|US4380238 *||21 Aug 1981||19 Apr 1983||Institute Straunann||Disposable applicator for mini-laparotomy using a clip method|
|US4394864 *||15 Apr 1981||26 Jul 1983||Jeffrey Sandhaus||Apparatus and method for effecting occlusion of the vas deferens|
|US4412539 *||11 May 1981||1 Nov 1983||United States Surgical Corporation||Repeating hemostatic clip applying instruments and multi-clip cartridges therefor|
|US4414721 *||7 Nov 1980||15 Nov 1983||Hufnagel Charles A||Occlusive clip and applicator for constricting flexible tubular members|
|US4449531 *||27 Aug 1981||22 May 1984||Ethicon, Inc.||Non-metallic, bio-compatible hemostatic clips with interlocking latch means|
|US4467803 *||1 Apr 1982||28 Aug 1984||Ngo Tuyen N||Oral temporary total hemostatic clamps|
|US4480641 *||5 Feb 1982||6 Nov 1984||Ethicon, Inc.||Tip configuration for a ligating clip applier|
|US4534351 *||20 Oct 1982||13 Aug 1985||Senmed, Inc.||Ligator|
|US4549544 *||31 Oct 1983||29 Oct 1985||Senmed, Inc.||Clip stop for a surgical ligating instrument|
|US4550729 *||5 Mar 1984||5 Nov 1985||Ethicon, Inc.||Non-metallic, bio-compatible hemostatic clips with interlocking latch means|
|US4570633 *||15 Apr 1985||18 Feb 1986||Ethicon, Inc.||Surgical clip applier instrument adapter jaws|
|US4616651 *||22 Aug 1985||14 Oct 1986||Ethicon, Inc.||Surgical clip applier instrument adapter jaws|
|US4638804 *||14 Jun 1985||27 Jan 1987||Ethicon, Inc.||Double-latched non-metallic, bio-compatible hemostatic clip|
|US4667671 *||15 Nov 1985||26 May 1987||Danzig Fred G||Apparatus for ligating blood vessels, nerves and other anatomical structures|
|US4671282 *||4 Oct 1985||9 Jun 1987||Tretbar Lawrence L||Clip apparatus|
|US4696396 *||9 Mar 1987||29 Sep 1987||Samuels Peter B||Hemostatic clip cartridge|
|US4708140 *||8 May 1986||24 Nov 1987||Baron Howard C||Atraumatic vascular balloon clamp|
|US4799481 *||8 Apr 1987||24 Jan 1989||Ethicon, Inc.||Surgical hemostatic clips|
|US4924864 *||27 Apr 1987||15 May 1990||Danzig Fred G||Apparatus and article for ligating blood vessels, nerves and other anatomical structures|
|US4961499 *||4 Jan 1990||9 Oct 1990||Pilling Co.||Hemostatic clip cartridge|
|US4979950 *||23 Jan 1989||25 Dec 1990||Ethicon, Inc.||Surgical hemostatic clips|
|US5163945 *||18 Oct 1991||17 Nov 1992||Ethicon, Inc.||Surgical clip applier|
|US5207691 *||1 Nov 1991||4 May 1993||Medical Scientific, Inc.||Electrosurgical clip applicator|
|US5279416 *||5 Jun 1992||18 Jan 1994||Edward Weck Incorporated||Ligating device cartridge with separable retainer|
|US5282812 *||10 Jul 1991||1 Feb 1994||Suarez Jr Luis||Clamp for use in vascular surgery|
|US5431675 *||13 Oct 1994||11 Jul 1995||United States Surgical Corporation||Locking mechanism for endoscopic or laparoscopic surgical instruments|
|US5487746 *||23 Nov 1994||30 Jan 1996||Yu; George W.||Surgical clip having a longitudinal opening through which clamped tissue protrudes|
|US5800452 *||4 Mar 1997||1 Sep 1998||Hastings; John A.||Body piercing instrument holder|
|US6044971 *||27 Jan 1998||4 Apr 2000||United States Surgical Corporation||Clip cartridge|
|US6086586 *||14 Sep 1998||11 Jul 2000||Enable Medical Corporation||Bipolar tissue grasping apparatus and tissue welding method|
|US6290575||1 Mar 1999||18 Sep 2001||John I. Shipp||Surgical ligation clip with increased ligating force|
|US6863675||20 Sep 2002||8 Mar 2005||Pilling Weck Incorporated||Ligating clip with integral penetrating hook|
|US6880699||27 Aug 2002||19 Apr 2005||Pilling Weck Incorporated||Cartridge for holding asymmetric surgical clips|
|US7052504||19 Nov 2002||30 May 2006||Teleflex Incorporated||Automated-feed surgical clip applier and related methods|
|US7131977||27 Aug 2002||7 Nov 2006||Pilling Weck Incorporated||Apparatus and method for removing a clip|
|US7211091||27 Aug 2002||1 May 2007||Pilling Weck Incorporated||Fingertip-actuated surgical clip applier and related methods|
|US7211092||19 Nov 2002||1 May 2007||Pilling Weck Incorporated||Automated-feed surgical clip applier and related methods|
|US7556499 *||7 Apr 2006||7 Jul 2009||Helmut Zepf Medizintechnik Gmbh||Dental forceps|
|US7572266||20 Oct 2004||11 Aug 2009||Young Wayne P||Clip applier tool having a discharge configuration|
|US7582095||12 Jun 2003||1 Sep 2009||Apollo Camera, L.L.C.||Surgical ligation clip and method for use thereof|
|US7678125||12 Nov 2003||16 Mar 2010||Apollo Camera, L.L.C.||Surgical ligation clip|
|US7928338||2 Feb 2007||19 Apr 2011||Plasma Surgical Investments Ltd.||Plasma spraying device and method|
|US8030849||11 Sep 2009||4 Oct 2011||Plasma Surgical Investments Limited||Pulsed plasma device and method for generating pulsed plasma|
|US8100926||14 Jul 2000||24 Jan 2012||Femcare Limited||Surgical clip|
|US8105325||7 Jul 2006||31 Jan 2012||Plasma Surgical Investments Limited||Plasma-generating device, plasma surgical device, use of a plasma-generating device and method of generating a plasma|
|US8109928||7 Jul 2006||7 Feb 2012||Plasma Surgical Investments Limited||Plasma-generating device, plasma surgical device and use of plasma surgical device|
|US8172870||9 Jun 2004||8 May 2012||Microline Surgical, Inc.||Ligation clip applier|
|US8337494||26 Jan 2012||25 Dec 2012||Plasma Surgical Investments Limited||Plasma-generating device having a plasma chamber|
|US8465487||25 Jan 2012||18 Jun 2013||Plasma Surgical Investments Limited||Plasma-generating device having a throttling portion|
|US8518063||2 Jul 2008||27 Aug 2013||Russell A. Houser||Arteriotomy closure devices and techniques|
|US8568430||16 Mar 2010||29 Oct 2013||Microline Surgical, Inc.||Surgical ligation clip|
|US8613742||29 Jan 2010||24 Dec 2013||Plasma Surgical Investments Limited||Methods of sealing vessels using plasma|
|US8735766||6 Aug 2007||27 May 2014||Plasma Surgical Investments Limited||Cathode assembly and method for pulsed plasma generation|
|US8900253 *||11 Mar 2004||2 Dec 2014||Covidien Lp||Clip applying apparatus with angled jaw|
|US8961541||31 Oct 2008||24 Feb 2015||Cardio Vascular Technologies Inc.||Vascular closure devices, systems, and methods of use|
|US8992567||21 Sep 2009||31 Mar 2015||Cardiovascular Technologies Inc.||Compressible, deformable, or deflectable tissue closure devices and method of manufacture|
|US9089319||22 Jul 2010||28 Jul 2015||Plasma Surgical Investments Limited||Volumetrically oscillating plasma flows|
|US9345460||9 Apr 2010||24 May 2016||Cardiovascular Technologies, Inc.||Tissue closure devices, device and systems for delivery, kits and methods therefor|
|US9468440||19 Jul 2013||18 Oct 2016||Aesculap Ag||Surgical clip applicator|
|US20040040875 *||27 Aug 2002||4 Mar 2004||Gallagher Richard J.||Cartridge for holding asymmetric surgical clips and method for loading surgical clips into a clip applier|
|US20040044352 *||27 Aug 2002||4 Mar 2004||Fowler David N.||Fingertip-actuated surgical clip applier and related methods|
|US20040044363 *||27 Aug 2002||4 Mar 2004||Fowler David N.||Apparatus and method for removing a clip|
|US20040059359 *||20 Sep 2002||25 Mar 2004||Wilson Donald F.||Ligating clip with integral penetrating hook|
|US20040167545 *||17 Aug 2001||26 Aug 2004||Sadler Kenneth George||Applicator for surgical clips|
|US20060124485 *||6 Oct 2005||15 Jun 2006||Kennedy Daniel L||Enhanced visibility cartridge with improved retainer|
|US20060184182 *||11 Mar 2004||17 Aug 2006||Ernest Aranyi||Clip applying apparatus with angled jaw|
|US20060228670 *||7 Apr 2006||12 Oct 2006||Helmut Zepf Medizintechnik Gmbh||Dental forceps|
|US20070021777 *||28 Sep 2006||25 Jan 2007||Fowler David N||Apparatus and method for removing a clip|
|US20070029292 *||7 Jul 2006||8 Feb 2007||Nikolay Suslov||Plasma-generating device, plasma surgical device and use of a plasma surgical device|
|US20140039524 *||7 Aug 2013||6 Feb 2014||Aesculap Ag||Surgical clip applicator|
|US20150032106 *||20 May 2014||29 Jan 2015||Covidien Lp||Vessel corset for use with electrosurgical forceps|
|US20150045816 *||28 Oct 2014||12 Feb 2015||Covidien Lp||Clip applying apparatus with angled jaw|
|DE3022087A1 *||12 Jun 1980||8 Jan 1981||Ethicon Inc||Haemostatische klammer, insbesondere aus kunststoff, und vorrichtung zum anbringen derselben|
|DE3106851A1 *||24 Feb 1981||25 Feb 1982||Ethicon Inc||Haemostatische klammer|
|DE3311830A1 *||31 Mar 1983||20 Oct 1983||Senco Products||Chirurgisches klammerinstrument und klammerntraeger|
|DE3419928A1 *||28 May 1984||4 Apr 1985||Noboru Funatsu||Chirurgische klammer und zange zur handhabung einer solchen klammer|
|DE19832739A1 *||21 Jul 1998||3 Feb 2000||Aesculap Ag & Co Kg||Surgical clip in U or V form for clamping hollow organs e.g. arteries|
|EP0077277A1 *||13 Oct 1982||20 Apr 1983||Nomel||Method and device for applying haemostatic clips, and haemostatic clips for use with this device|
|EP0201344A2||9 May 1986||12 Nov 1986||Ethicon Inc.||Ligating clip and clip applier|
|EP0357377A2 *||30 Aug 1989||7 Mar 1990||CODMAN & SHURTLEFF INC.||Toggle action aneurysm clip|
|EP0357377A3 *||30 Aug 1989||28 Nov 1990||Codman & Shurtleff Inc.||Toggle action aneurysm clip|
|EP0482861A1 *||21 Oct 1991||29 Apr 1992||Pilling Weck Incorporated||Hemostatic clip cartridge|
|EP1608272A4 *||11 Mar 2004||11 Mar 2015||Covidien Lp||Clip applying apparatus with angled jaw|
|WO1993008741A1 *||14 Oct 1992||13 May 1993||Medical Scientific, Inc.||Electrosurgical clip applicator|
|WO2001005309A1 *||14 Jul 2000||25 Jan 2001||Femcare Limited||Surgical clip|
|U.S. Classification||606/158, 606/207, 206/438, 24/115.00A, 606/142|
|International Classification||A61B17/12, A61B17/122, A61B17/28|
|Cooperative Classification||A61B17/2812, A61B17/1222, A61B17/122|
|European Classification||A61B17/28D, A61B17/122C, A61B17/122|