US3034509A - Surgical tubing - Google Patents
Surgical tubing Download PDFInfo
- Publication number
- US3034509A US3034509A US53890A US5389060A US3034509A US 3034509 A US3034509 A US 3034509A US 53890 A US53890 A US 53890A US 5389060 A US5389060 A US 5389060A US 3034509 A US3034509 A US 3034509A
- Authority
- US
- United States
- Prior art keywords
- tubing
- surgical
- polyethylene
- blood
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 polyethylene Polymers 0.000 description 19
- 239000004698 Polyethylene Substances 0.000 description 11
- 229920000573 polyethylene Polymers 0.000 description 11
- 239000008280 blood Substances 0.000 description 10
- 210000004369 blood Anatomy 0.000 description 10
- 229920002545 silicone oil Polymers 0.000 description 9
- 239000007788 liquid Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229920013716 polyethylene resin Polymers 0.000 description 4
- 230000023555 blood coagulation Effects 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002642 intravenous therapy Methods 0.000 description 1
- 229920001558 organosilicon polymer Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- SRVJKTDHMYAMHA-WUXMJOGZSA-N thioacetazone Chemical compound CC(=O)NC1=CC=C(\C=N\NC(N)=S)C=C1 SRVJKTDHMYAMHA-WUXMJOGZSA-N 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/08—Tubes; Storage means specially adapted therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
- Y10T428/1393—Multilayer [continuous layer]
Definitions
- This invention relates to surgical or medical tubing, and more particularly, concerns tubing or cannula formed of polyethylene.
- polyethylene tubing has been extensively used for surgical and medical purposes, it has been found that such tubin may be modified by specific formulation of the polyethylene to effect substantial improvement in a number of its properties particularly pertinent to its surgical or medical usage.
- one object of this invention is to provide an improved tubing or cannula formed of a modified polyethylene resin, which in use retards blood coagulation over extended periods of time, thereby minimizing the formation of obstructions in the tubing due to coagulated blood.
- Another object of this invention is to provide an improved polyethylene tubing for surgical or medical usage, which when in contact with tissue over extended periods of time, does not give rise to toxic reactions or irritation of the tissue.
- a further object of this invention is to provide an improved cannula formed of modified polyethylene resin, which displays increased inertness with respect to blood, thereby materially decreasing deleterious effects on the blood as an incident to the surgical or medical usage of such cannula.
- Still another object of this invention is to provide an improved surgical or medical tubing or cannula which permits a maximum rate of liquid flow therethrough, thereby facilitating the transmission of nutrient solutions, blood or other liquid media being transported by way of such tubing or cannula.
- polyethylene resin has admixed therewith a suitable amount of organosilicon polymers, particularly, polymers in the form of silicone oils or liquids.
- organosilicon polymers particularly, polymers in the form of silicone oils or liquids.
- the mixture is extruded through suitable extruding means to form tubing of a selected inner and outer diameter.
- the silicone polymer is well distributed through the Walls of the tubing and such tubing when used in connection with surgical or medical procedures, has been found to be of uniform character in respect to a number of enhanced properties which make the same particularly suitable for intravenous therapy, transfusions, as well as a variety of other surgical or medical procedures.
- the polyethylene is admixed with from about 0.15 to about 1.00% by weight of a silicone oil sold under the designation of 200 Fluids by Dow Corning Corp. or G E Silicone Oils by General Electric Company.
- a silicone oil sold under the designation of 200 Fluids by Dow Corning Corp. or G E Silicone Oils by General Electric Company.
- Such silicone derivatives are essentially dimethyl derivatives of the polysiloxanes and may have viscosities ranging from 0.65 to over 1,000,000 centistokes at 25 C. However, for the particular purpose herein, oils having viscosities of from about 250 to about 450 centistokes at 25 C. are preferred.
- Tubing was formed from polyethylene resin havmg a content of 0.5% by weight of silicone oil, by extrusion of the resin-oil mixture.
- the result-ant tubing was found to have a high degree of inertness with respect to blood and after implant over extended periods of time, the tissues were found to be free of toxic effects or irritation. Also, the tubing had excellent flow characteristics for blood and nutrient solutions and retarded blood coagulation over long periods of usage.
- Tubing formed from the mixture of polyethylene and silicone oil was produced in a wide range of sizes vary ing from .011 ID. x .024" OD. to .500" ID. x .560 OD.
- the silicone oil content may be of the order of from about 0.35 to about 0.40% by weight.
- the silicone oil content may be increased to from about 0.5 to about 0.6% by weight.
- a surgical tubing for contact with human tissue or blood comprising polyethylene and a polyorganosiloxane distributed homogeneously and uniformly throughout the thickness of the tubing wall in amounts of from about 0.15 to about 1.00% by weight, wherein said polyorganosiloxane tends to migrate to the surfaces of said tubing.
- a surgical tubing for contact with human tissue or blood comprising an extruded body of polyethylene and polymethylsiloxane, said polymet-hylsiloxane being present in amounts of from about 0.4 to about 0.5% by weight and homogeneously and uniformly distributed throughout the thickness of the tubing wall.
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Description
nited rates 'Patent @fihce 3,034,509 Patented May 15, 1962 3,034,509 SURGICAL TUBING Richard K. Bernstein, Bronx, and George Gods, New York, N.Y., assignors to Clay-Adams, Inc., New York, N.Y., a corporation of New York No Drawing. Filed Sept. 6, 1960, Ser. No. 53,890 6 Claims. (Cl. 128348) This invention relates to surgical or medical tubing, and more particularly, concerns tubing or cannula formed of polyethylene.
While polyethylene tubing has been extensively used for surgical and medical purposes, it has been found that such tubin may be modified by specific formulation of the polyethylene to effect substantial improvement in a number of its properties particularly pertinent to its surgical or medical usage.
Accordingly, one object of this invention is to provide an improved tubing or cannula formed of a modified polyethylene resin, which in use retards blood coagulation over extended periods of time, thereby minimizing the formation of obstructions in the tubing due to coagulated blood.
Another object of this invention is to provide an improved polyethylene tubing for surgical or medical usage, which when in contact with tissue over extended periods of time, does not give rise to toxic reactions or irritation of the tissue.
A further object of this invention is to provide an improved cannula formed of modified polyethylene resin, which displays increased inertness with respect to blood, thereby materially decreasing deleterious effects on the blood as an incident to the surgical or medical usage of such cannula.
Still another object of this invention is to provide an improved surgical or medical tubing or cannula which permits a maximum rate of liquid flow therethrough, thereby facilitating the transmission of nutrient solutions, blood or other liquid media being transported by way of such tubing or cannula.
Other objects of this invention will in part be obvious and in part hereinafter pointed out.
In accordance with the instant invention, polyethylene resin has admixed therewith a suitable amount of organosilicon polymers, particularly, polymers in the form of silicone oils or liquids. The mixture is extruded through suitable extruding means to form tubing of a selected inner and outer diameter.
The silicone polymer is well distributed through the Walls of the tubing and such tubing when used in connection with surgical or medical procedures, has been found to be of uniform character in respect to a number of enhanced properties which make the same particularly suitable for intravenous therapy, transfusions, as well as a variety of other surgical or medical procedures.
Thus, the polyethylene is admixed with from about 0.15 to about 1.00% by weight of a silicone oil sold under the designation of 200 Fluids by Dow Corning Corp. or G E Silicone Oils by General Electric Company. Such silicone derivatives are essentially dimethyl derivatives of the polysiloxanes and may have viscosities ranging from 0.65 to over 1,000,000 centistokes at 25 C. However, for the particular purpose herein, oils having viscosities of from about 250 to about 450 centistokes at 25 C. are preferred.
Tubing was formed from polyethylene resin havmg a content of 0.5% by weight of silicone oil, by extrusion of the resin-oil mixture. The result-ant tubing was found to have a high degree of inertness with respect to blood and after implant over extended periods of time, the tissues were found to be free of toxic effects or irritation. Also, the tubing had excellent flow characteristics for blood and nutrient solutions and retarded blood coagulation over long periods of usage.
Tubing formed from the mixture of polyethylene and silicone oil, was produced in a wide range of sizes vary ing from .011 ID. x .024" OD. to .500" ID. x .560 OD. For the smaller sizes of tubing, the silicone oil content may be of the order of from about 0.35 to about 0.40% by weight. For the larger sizes of tubing, the silicone oil content may be increased to from about 0.5 to about 0.6% by weight.
It has been found that the substantially uniform distribution of the polymethylsiloxane through the polyethylene forming the tubing Wall is responsible for the optimum properties exhibited in surgical and medical usage, including inertness, freedom from toxic reactions and irritation, retarding blood coagulation and the like. Furthermore such properties are maintained through the normal life of the tubing, apparently by reason of the slight migration of the polymethylsiloxane through the tubing wall to the inner and outer surfaces thereof.
As various changes might be made in the embodiments of the invention disclosed herein without departing from the spirit thereof, it is understood that all matter herein described shall be deemed illustrative and not limiting except as set forth in the appended claims.
What is claimed is:
1. A surgical tubing for contact with human tissue or blood comprising polyethylene and a polyorganosiloxane distributed homogeneously and uniformly throughout the thickness of the tubing wall in amounts of from about 0.15 to about 1.00% by weight, wherein said polyorganosiloxane tends to migrate to the surfaces of said tubing.
2. A surgical tubing for contact with human tissue or blood comprising an extruded body of polyethylene and polymethylsiloxane, said polymet-hylsiloxane being present in amounts of from about 0.4 to about 0.5% by weight and homogeneously and uniformly distributed throughout the thickness of the tubing wall.
3. A surgical tubing for contact with human tissue or blood comprising polyethylene and about 0.5 by weight of a silicone oil distributed homogeneously and uniformly through the wall of the tubing for migration to the wall surfaces of said tubing.
4. A surgical tubing as in claim 3 wherein said silicone oil is polymethylsiloxane.
5. A surgical tubing as in claim 4 wherein said polymethylsilox-ane has a viscosity of from about 250 to about 450 centistokes at 25 C.
6. A surgical tubing for contact with human tissue or blood, comprising a tubing of extruded polyethylene and about 0.5 by weight of liquid polydimethylsiloxane having a viscosity of about 350 centistokes at 25 C., said polydimethylsiloxane being homogeneously and uniformly distributed through the wall of said tubing.
References Cited in the file of this patent McGregor: Silicones in Medicine aed Surgery, received in R0. Lib., June 20, 1957, pages 19-20 required, 167$ilicone.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53890A US3034509A (en) | 1960-09-06 | 1960-09-06 | Surgical tubing |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53890A US3034509A (en) | 1960-09-06 | 1960-09-06 | Surgical tubing |
Publications (1)
Publication Number | Publication Date |
---|---|
US3034509A true US3034509A (en) | 1962-05-15 |
Family
ID=21987247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US53890A Expired - Lifetime US3034509A (en) | 1960-09-06 | 1960-09-06 | Surgical tubing |
Country Status (1)
Country | Link |
---|---|
US (1) | US3034509A (en) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3962519A (en) * | 1968-04-26 | 1976-06-08 | Messrs. Willy Rusch, K.G. | Rubber article or instrument and method of producing the same |
US4177182A (en) * | 1974-10-28 | 1979-12-04 | Terumo Corp. | Polyvinyl chloride series resin medical product implements and method of manufacturing the same using siloxane oil additive |
US4299256A (en) * | 1980-10-06 | 1981-11-10 | Baxter Travenol Laboratories, Inc. | Coextruded silicone-containing tubing having long term frictional lubrication properties |
DE3146827A1 (en) * | 1980-05-07 | 1983-06-01 | Sterling, Robert E., 33553 New Port Richey, Fla. | "SUBSTANCE COMPOSITION" |
US4389206A (en) * | 1980-10-09 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Centrifugal processing apparatus and rotatable processing bowl apparatus |
US4389207A (en) * | 1981-03-16 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system |
US5639810A (en) * | 1993-04-15 | 1997-06-17 | Cobe Laboratories, Inc. | Internally lubricated elastomers for use in biomedical applications |
US5912291A (en) * | 1992-02-28 | 1999-06-15 | Res Development Corporation | Thermoplastic polymers with polyfluoroalkylsiloxane modified surfaces |
US6431219B1 (en) | 2001-02-05 | 2002-08-13 | Alaris Medical Systems, Inc. | Coextruded tubing |
US6541558B1 (en) | 1996-10-09 | 2003-04-01 | Res Development Corporation | Thermoplastic polymers with dispersed fluorocarbon additives |
US6794438B2 (en) | 2000-10-17 | 2004-09-21 | Res Development Corporation | Thermoset polymers with dispersed fluorocarbon additives |
US6841602B2 (en) | 2000-10-17 | 2005-01-11 | Res Development Corporation | Thermoset polymers with polyfluoroalkylsiloxane modified surfaces |
US20060194911A1 (en) * | 2005-02-25 | 2006-08-31 | Sterling Robert E | Thermoset polymers with dispersed fluorocarbon additives |
US20070197702A1 (en) * | 2006-02-23 | 2007-08-23 | Victor Nasreddine | Rubber compositions having improved physical and low temperature properties |
WO2015025626A1 (en) * | 2013-08-20 | 2015-02-26 | オリンパス株式会社 | Material for medical tubes, and medical tube |
-
1960
- 1960-09-06 US US53890A patent/US3034509A/en not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
None * |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3962519A (en) * | 1968-04-26 | 1976-06-08 | Messrs. Willy Rusch, K.G. | Rubber article or instrument and method of producing the same |
US4177182A (en) * | 1974-10-28 | 1979-12-04 | Terumo Corp. | Polyvinyl chloride series resin medical product implements and method of manufacturing the same using siloxane oil additive |
DE3146827A1 (en) * | 1980-05-07 | 1983-06-01 | Sterling, Robert E., 33553 New Port Richey, Fla. | "SUBSTANCE COMPOSITION" |
US4299256A (en) * | 1980-10-06 | 1981-11-10 | Baxter Travenol Laboratories, Inc. | Coextruded silicone-containing tubing having long term frictional lubrication properties |
US4389206A (en) * | 1980-10-09 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Centrifugal processing apparatus and rotatable processing bowl apparatus |
US4389207A (en) * | 1981-03-16 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system |
US5912291A (en) * | 1992-02-28 | 1999-06-15 | Res Development Corporation | Thermoplastic polymers with polyfluoroalkylsiloxane modified surfaces |
US5639810A (en) * | 1993-04-15 | 1997-06-17 | Cobe Laboratories, Inc. | Internally lubricated elastomers for use in biomedical applications |
US6541558B1 (en) | 1996-10-09 | 2003-04-01 | Res Development Corporation | Thermoplastic polymers with dispersed fluorocarbon additives |
US6841602B2 (en) | 2000-10-17 | 2005-01-11 | Res Development Corporation | Thermoset polymers with polyfluoroalkylsiloxane modified surfaces |
US6794438B2 (en) | 2000-10-17 | 2004-09-21 | Res Development Corporation | Thermoset polymers with dispersed fluorocarbon additives |
US6431219B1 (en) | 2001-02-05 | 2002-08-13 | Alaris Medical Systems, Inc. | Coextruded tubing |
US20060194911A1 (en) * | 2005-02-25 | 2006-08-31 | Sterling Robert E | Thermoset polymers with dispersed fluorocarbon additives |
US20070197702A1 (en) * | 2006-02-23 | 2007-08-23 | Victor Nasreddine | Rubber compositions having improved physical and low temperature properties |
US7741392B2 (en) | 2006-02-23 | 2010-06-22 | Lanxess Inc. | Rubber compositions having improved physical and low temperature properties |
WO2015025626A1 (en) * | 2013-08-20 | 2015-02-26 | オリンパス株式会社 | Material for medical tubes, and medical tube |
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