US2888923A - New ampoule-syringe - Google Patents

New ampoule-syringe Download PDF

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US2888923A
US2888923A US548496A US54849655A US2888923A US 2888923 A US2888923 A US 2888923A US 548496 A US548496 A US 548496A US 54849655 A US54849655 A US 54849655A US 2888923 A US2888923 A US 2888923A
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syringe
piston
casing
hollow
needle
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US548496A
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Reis Antonio Da Cunha
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing

Definitions

  • this permits a saving of the material to be dispensed since frequently much of this material is left in its original container.
  • the invention contemplates the provision of a cylinder body wherein is disposed a piston comprising first and second concentric hollow tubes having means thereon for fixing the relative positions of the tubes.
  • the hollow tubes are displaced in a predetermined manner which will be described below so that the piston operates firstly, to prepare a material in the syringe for injection, and secondly, as a simple piston to eject the material from the syringe.
  • FIG. 1 is an elevational view of a syringe provided in accordance with the invention with the components thereof assuming relative positions for effecting a movement of the syringe piston in the body of the syringe;
  • Fig. 2 is an elevational view of the syringe of Fig. 1 with the parts of the syringe in position for storage;
  • Fig. 3 is an axial section of the syringe with certain of the parts disengaged so as to facilitate an understanding of the construction
  • Fig. 4 illustrates the outer body of the syringe
  • Fig. 5 illustrates a nozzle cover employed by the syringe
  • Fig. 6 illustrates one of the members of the piston of the syringe
  • Fig. 7 illustrates a plug employed in the syringe for confining the material to be dispensed
  • Fig. 8 illustrates a washer employed in connection with the piston of the syringe
  • Fig. 9 illustrates a further member of the piston of the syringe
  • Fig. 10 illustrates a head which is connected to the piston of the syringe for manipulation thereof
  • Fig. 11 illustrates a capsule in which material may be stored within the syringe.
  • Figs. 1-3 The complete collection of elements necessary for providing a syringe in accordance with the invention is illustrated in each of Figs. 1-3, the separate components of the syringe being illustrated in Figs. 4-11.
  • the illustrated syringe provides for accommodating, within its interi'or, one or more materials to be dispensed, these materials being hermetically sealed within the syringe and the syringe requiring an injection needle to be affixed to its end for purposes of dispensing the stored material.
  • the syringe includes an outer cylindrical body 1 hav ing a smooth internal bore and terminating in a conical nipple or nozzle 2 the interior of which is hollow so that the bore of the casing 1 can communicate to the outside.
  • the cylindrical outer body or casing 1 is shown more particularly in, Fig. 4 wherein it can be seen that the nipple 2: is afiixed in conventional manner at 7 to the main body of this component. It can also be seen that the nipple 2 is provided with an external thread 3.
  • the casing 1 accommodates a piston which includes an inner hollow tube 13 externally threaded along the greater part of its length and a second hollow tube 8 which is internally threaded in such a manner that it is capablev of threadably engaging the first hollow tube 13.
  • the hollow body 8 defines, at one end, an annular groove 10 capable of accommodating a ring or rubber washer 11 (see Fig. 8) so that an air tight seal is provided between the piston and the internal bore of the casing I.
  • the washer 11 permits a sl'idable movement between the piston and the casing.
  • the hollow body 8 defines an opening 9 in which is accommodateda plug 18 (see Fig. 7) which itself defines a blind bore.
  • the blind bore is adapted for accommodating the lower extremity of a hollow needle 15 which is connected with an ampoule or capsule 17 in which may be storeda material which is to be dispensed.
  • This capsule is normally stored in the interior of the piston in a manner which will hereinafter be made apparent.
  • a head or knob 14 capable of being afiixed to the hollow body 13 in conventional manner such as by welding or by a set screw.
  • a conical cap (see Fig. 5) having a rim 6 adapted for tightly abutting the lower extremity of the casing 1, the cap being hollow and having an internal thread 5 capable of engaging the thread 3 of the nipple 2. It is to be noted that the cap can be provided with a pin. 4 capable of penetrating the opening of the nipple 2 so as to block the same.
  • the hollow tubes 8 and 13 are engaged in such a manner that the needle 15 of the capsule 17 rests in the blind bore or well of the plug 18 with the head 14 resting against the upper extremity of the casing 1.
  • the respective threads of the tubes 8 and 13 are not fully engaged so that upon a turning of the tube 13 in the tube 8 in a direction so as to cause a further engagement between these tubes, the needle 15 will be caused to penetrate the plug 18 whereupon the material from the capsule 17 will be emptied into that portion of the casing which is confined between the lower extremity of the casing and the lower end of the piston.
  • material can be stored in the space 16 and this material can be re-positioned in a manner similar to that indicated above.
  • the cap With the material adjacent the nipple 2 it is possible to unscrew the inner hollow tube 13 substantially but not completely from the hollow tube 8 so as to increase the effective length of the piston. With the piston so extended, the cap can be removed from the nipple 2 and an injection needle threaded thereupon. The syringe can then be used in conventional manner.
  • the invention provides a syringe in which the material to be dispensed can be stored.
  • the invention morer 3 over, provides for conveniently releasing the material for injection and in achieving this objective provides for accomplishing its purpose with a minimum effort and with no exposure of any of the elements or materials which will be used for medical purposes to the possibility of contamination.
  • a syringe for use with a sterile needle comprising a casing adapted for communicably engaging said sterile needle and a piston slidably engaged within said casing for ejecting material through said sterile needle, said piston comprising a first hollow tube engaging said casing, a second hollow tube within and threadably engaging said first hollow tube, said second hollow tube being axially adjustable with respect to said first hollow tube and adapted for substantially complete insertion therein whereby the piston length may be controlled, and means on said first and second hollow tubes for fixing the relative positions thereof.
  • a syringe as claimed in claim 2 comprising a stud, said first hollow tube being provided with an end aperture for engaging said stud, a capsule positioned in said second hollow tube, and a needle afiixed to said capsule, said second hollow tube being provided with an end aperture for the passage of said needle, said plug being provided with a well for accommodating the end of said needle with said first and sepond hollow tubes at a predetermined axial adjustment;
  • a syringe as claimed in claim 4 comprising a threaded nipple on said casing communicating with said space and adapted for engaging said sterile needle, and a threaded cap for engaging and sealing off said nipple.
  • a syringe as claimed in claim 5 comprising a head member engaging said second hollow tube for the manipulation of said piston.
  • a syringe as claimed in claim 6 comprising a mounting on said casing for detachably supporting said sterile needle whereby said sterile needle is conveniently accessible for attachment to said nipple.

Description

June 2, 1959 A. DA CUNHA REIS NEW AMPOULE-SYRINGE 2 Sheets-Sheet 1 Filed Nov. 22, 1955 J1me 1959 A. DA CUNHA REES 2,888,923
NEW AMPOULE-SYRINGE Filed Nov. 22, 1955 2 Sheets-Sheet 2 United States Patent NEW AMPOULE-SYRINGE Antonio da Cunha Reis, Lisbon, Portugal Application November 22, 1955, Serial N 0. 548,496
7 Claims. (Cl. 128-218) This invention relates to syringes.
It is an object of the invention to provide an improved syringe which enables preparation for injections in a period of time.
It is a further object of the invention to provide an improved syringe capable of working equally Well with oil and aqueous solutions and with substances provided in the form of a powder or crystal which are to be dissolved in a fluid carrier.
It is still a further object of the invention to provide an improved syringe with which it is not necessary to draw the material to be dispensed into the same through an injection needle. Advantageously this permits a saving of the material to be dispensed since frequently much of this material is left in its original container.
In achieving the above and other of its objectives, the invention contemplates the provision of a cylinder body wherein is disposed a piston comprising first and second concentric hollow tubes having means thereon for fixing the relative positions of the tubes. The hollow tubes are displaced in a predetermined manner which will be described below so that the piston operates firstly, to prepare a material in the syringe for injection, and secondly, as a simple piston to eject the material from the syringe.
To facilitate an understanding of the invention, a preferred embodiment thereof will next be explained, in detail, with reference to the accompanying drawing in which:
Fig. 1 is an elevational view of a syringe provided in accordance With the invention with the components thereof assuming relative positions for effecting a movement of the syringe piston in the body of the syringe;
Fig. 2 is an elevational view of the syringe of Fig. 1 with the parts of the syringe in position for storage;
Fig. 3 is an axial section of the syringe with certain of the parts disengaged so as to facilitate an understanding of the construction;
Fig. 4 illustrates the outer body of the syringe;
Fig. 5 illustrates a nozzle cover employed by the syringe;
Fig. 6 illustrates one of the members of the piston of the syringe;
Fig. 7 illustrates a plug employed in the syringe for confining the material to be dispensed;
Fig. 8 illustrates a washer employed in connection with the piston of the syringe;
Fig. 9 illustrates a further member of the piston of the syringe;
Fig. 10 illustrates a head which is connected to the piston of the syringe for manipulation thereof; and
Fig. 11 illustrates a capsule in which material may be stored within the syringe.
The complete collection of elements necessary for providing a syringe in accordance with the invention is illustrated in each of Figs. 1-3, the separate components of the syringe being illustrated in Figs. 4-11. The illustrated syringe provides for accommodating, within its interi'or, one or more materials to be dispensed, these materials being hermetically sealed within the syringe and the syringe requiring an injection needle to be affixed to its end for purposes of dispensing the stored material.
The syringe includes an outer cylindrical body 1 hav ing a smooth internal bore and terminating in a conical nipple or nozzle 2 the interior of which is hollow so that the bore of the casing 1 can communicate to the outside.
The cylindrical outer body or casing 1 is shown more particularly in, Fig. 4 wherein it can be seen that the nipple 2: is afiixed in conventional manner at 7 to the main body of this component. It can also be seen that the nipple 2 is provided with an external thread 3.
The casing 1 accommodates a piston which includes an inner hollow tube 13 externally threaded along the greater part of its length and a second hollow tube 8 which is internally threaded in such a manner that it is capablev of threadably engaging the first hollow tube 13. The hollow body 8 defines, at one end, an annular groove 10 capable of accommodating a ring or rubber washer 11 (see Fig. 8) so that an air tight seal is provided between the piston and the internal bore of the casing I. The washer 11, of course, permits a sl'idable movement between the piston and the casing.
The hollow body 8 defines an opening 9 in which is accommodateda plug 18 (see Fig. 7) which itself defines a blind bore. The blind bore is adapted for accommodating the lower extremity of a hollow needle 15 which is connected with an ampoule or capsule 17 in which may be storeda material which is to be dispensed. This capsule is normally stored in the interior of the piston in a manner which will hereinafter be made apparent.
To enable a manipulation of the piston which consists of the hollow members 8 and 13 there is provided a head or knob 14 capable of being afiixed to the hollow body 13 in conventional manner such as by welding or by a set screw.
To close off the nipple 2 there is provided a conical cap (see Fig. 5) having a rim 6 adapted for tightly abutting the lower extremity of the casing 1, the cap being hollow and having an internal thread 5 capable of engaging the thread 3 of the nipple 2. It is to be noted that the cap can be provided with a pin. 4 capable of penetrating the opening of the nipple 2 so as to block the same.
With the syringe in storage position as indicated in Fig. 2, the hollow tubes 8 and 13 are engaged in such a manner that the needle 15 of the capsule 17 rests in the blind bore or well of the plug 18 with the head 14 resting against the upper extremity of the casing 1. In this position the respective threads of the tubes 8 and 13 are not fully engaged so that upon a turning of the tube 13 in the tube 8 in a direction so as to cause a further engagement between these tubes, the needle 15 will be caused to penetrate the plug 18 whereupon the material from the capsule 17 will be emptied into that portion of the casing which is confined between the lower extremity of the casing and the lower end of the piston. Alternatively material can be stored in the space 16 and this material can be re-positioned in a manner similar to that indicated above.
With the material adjacent the nipple 2 it is possible to unscrew the inner hollow tube 13 substantially but not completely from the hollow tube 8 so as to increase the effective length of the piston. With the piston so extended, the cap can be removed from the nipple 2 and an injection needle threaded thereupon. The syringe can then be used in conventional manner.
From what has been stated above it will be appreciated that the invention provides a syringe in which the material to be dispensed can be stored. The invention, morer 3 over, provides for conveniently releasing the material for injection and in achieving this objective provides for accomplishing its purpose with a minimum effort and with no exposure of any of the elements or materials which will be used for medical purposes to the possibility of contamination.
There will now be obvious to those skilled in the art many modifications and variations of the structure set forth which do not depart essentially from the spirit of the invention as defined in the following claims.
What is claimed is:
l. A syringe for use with a sterile needle comprising a casing adapted for communicably engaging said sterile needle and a piston slidably engaged within said casing for ejecting material through said sterile needle, said piston comprising a first hollow tube engaging said casing, a second hollow tube within and threadably engaging said first hollow tube, said second hollow tube being axially adjustable with respect to said first hollow tube and adapted for substantially complete insertion therein whereby the piston length may be controlled, and means on said first and second hollow tubes for fixing the relative positions thereof.
2. A syringe as claimed in claim 1 wherein said first hollow tube is provided with an annular groove and further comprising a ring engaging said groove for slidably sealing said piston with said casing.
3. A syringe as claimed in claim 2 comprising a stud, said first hollow tube being provided with an end aperture for engaging said stud, a capsule positioned in said second hollow tube, and a needle afiixed to said capsule, said second hollow tube being provided with an end aperture for the passage of said needle, said plug being provided with a well for accommodating the end of said needle with said first and sepond hollow tubes at a predetermined axial adjustment;
4. A syringe as claimed in claim 3 wherein said first and second hollow tubes are axially adjustable to permit the forcing of said needle through said plug whereby said capsule empties intothe space defined between said piston and said casing.
5. A syringe as claimed in claim 4 comprising a threaded nipple on said casing communicating with said space and adapted for engaging said sterile needle, and a threaded cap for engaging and sealing off said nipple.
6. A syringe as claimed in claim 5 comprising a head member engaging said second hollow tube for the manipulation of said piston.
7. A syringe as claimed in claim 6 comprising a mounting on said casing for detachably supporting said sterile needle whereby said sterile needle is conveniently accessible for attachment to said nipple.
References Cited the file of this patent UNITED STATES PATENTS 743,743 McCulloch Nov. 10, 1903 1,144,343 Benmosche et a1 June 29, 1915 1,234,582 Trueblood July 24, 1917 1,799,463 Hein Apr. 7, 1931 2,244,969 Smith June 10, 1941 2,684,068 Orens July 20, 1954 FOREIGN PATENTS 357,803 France Nov. 24, 1905 950,588 France Mar. 28, 1949
US548496A 1955-10-18 1955-11-22 New ampoule-syringe Expired - Lifetime US2888923A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US548496A US2888923A (en) 1955-10-18 1955-11-22 New ampoule-syringe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB29645/55A GB815749A (en) 1955-10-18 1955-10-18 Improvements in or relating to syringes
US548496A US2888923A (en) 1955-10-18 1955-11-22 New ampoule-syringe

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US2888923A true US2888923A (en) 1959-06-02

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US (1) US2888923A (en)
BE (1) BE541390A (en)
CH (1) CH340314A (en)
FR (1) FR1137565A (en)
GB (1) GB815749A (en)

Cited By (35)

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US3931815A (en) * 1973-08-29 1976-01-13 Jintan Terumo Company, Ltd. Assembly having an adapter and a holder with a double ended needle
US4507117A (en) * 1983-07-11 1985-03-26 Vining Herbert C Syringe apparatus with retractable needle
US4592744A (en) * 1985-08-14 1986-06-03 The University Of Virginia Alumni Patents Foundation Self-resheathing needle assembly
US4650468A (en) * 1986-02-26 1987-03-17 Jennings Jr Baldwin P Medical syringe
US4732302A (en) * 1985-07-25 1988-03-22 Muehlbauer Ernst Device for the metered discharge of dental material
US4846811A (en) * 1987-01-29 1989-07-11 International Medical Innovators, Inc. Sliding sheath for medical needles
US4874384A (en) * 1987-07-13 1989-10-17 International Medical Innovators, Inc. Needle safety guard
US4915699A (en) * 1988-10-19 1990-04-10 Elliot Kornberg Syringe
US4935015A (en) * 1988-12-14 1990-06-19 Hall John E Syringe apparatus with retractable needle
US4969877A (en) * 1988-10-19 1990-11-13 The Pascall Medical Corporation Syringe
US5019043A (en) * 1988-08-05 1991-05-28 Vincent Miguel Segui Pastor Syringe with needle retraction capability
US5154699A (en) * 1988-03-01 1992-10-13 Ryan Medical, Inc. Safety winged needle device for use with fistulas
US5188601A (en) * 1991-11-06 1993-02-23 King Richard J Disposable safety syringe
US5263933A (en) * 1988-12-14 1993-11-23 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5324272A (en) * 1990-07-27 1994-06-28 Sterling Winthrop Inc. Multiple-celled safety package, needle guard and safe disposal module for prefilled medication cartridge
US5338311A (en) * 1993-08-23 1994-08-16 Mahurkar Sakharam D Hypodermic needle assembly
US5346474A (en) * 1991-11-06 1994-09-13 Design & Engineering Associates Disposable safety syringe
US5372590A (en) * 1990-07-27 1994-12-13 Habley Medical Technology Corporation Multi-celled safety package, needle guard and safety disposal module with sleeve for prefilled medication cartridges
US5415638A (en) * 1988-12-14 1995-05-16 Inviro Medical Devices, Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5462531A (en) * 1988-12-14 1995-10-31 Inviro Medical Devices Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5484421A (en) * 1993-08-30 1996-01-16 Smocer; Anthony V. Safety syringe
US5836921A (en) * 1993-08-23 1998-11-17 Mahurkar; Sakharam D. Hypodermic needle assembly
US6033386A (en) * 1988-12-14 2000-03-07 Inviro Medical Devices, Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US6117112A (en) * 1997-11-18 2000-09-12 Mahurkar; Sakharam D. Single-use safety syringe
US6183464B1 (en) 1998-06-01 2001-02-06 Inviro Medical Devices Ltd. Safety syringe with retractable needle and universal luer coupling
WO2001052923A1 (en) * 2000-01-19 2001-07-26 Scimed Life Systems, Inc. Shear-sensitive injectable delivery system
US6280401B1 (en) 1993-08-23 2001-08-28 Sakharam D. Mahurkar Hypodermic needle assembly
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
WO2002017801A2 (en) * 2000-07-14 2002-03-07 Kyphon Inc. Systems and methods for treating vertebral bodies
MD3048C2 (en) * 2004-03-01 2006-12-31 Анатол БАТЫР Syringe-ampoule
US7481797B2 (en) 2001-11-28 2009-01-27 Mahurkar Sakharam D Retractable needle single use safety syringe
US7918821B2 (en) 2009-05-05 2011-04-05 Mahurkar Sakharam D Universal safety syringe
JP2013507216A (en) * 2009-10-16 2013-03-04 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Arrangement for use in a drug delivery device
WO2015134307A1 (en) * 2014-03-04 2015-09-11 Merck Sharp & Dohme Corp. Prefilled disposable injection device
US11439768B2 (en) * 2019-07-17 2022-09-13 Wagner Florexil Compartmentalized syringe for combined medicine and flush solution

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US3489147A (en) * 1964-07-21 1970-01-13 Joseph Denman Shaw Combination mixing and injecting medical syringe
US5059179A (en) * 1989-05-15 1991-10-22 David Quatrochi Non-reusable syringe assembly
JP3108077B2 (en) * 1989-06-08 2000-11-13 住友製薬株式会社 Formulation dosing device
CA2591420A1 (en) * 2004-12-09 2006-06-15 West Pharmaceutical Services, Inc. Breech loaded fixed needle syringe and automatic injection device having the same

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US743743A (en) * 1903-06-13 1903-11-10 John Howard Mcculloch Hypodermic syringe.
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US1144343A (en) * 1913-08-22 1915-06-29 Moses Benmosche Hypodermic syringe.
US1234582A (en) * 1916-12-14 1917-07-24 Barclay T Trueblood Hypodermic syringe.
US1799463A (en) * 1926-03-19 1931-04-07 George N Hein Hypodermic syringe
US2244969A (en) * 1940-05-20 1941-06-10 Arthur E Smith Ampoule syringe
FR950588A (en) * 1947-07-23 1949-09-30 Improvements to devices allowing to achieve or interrupt communication between two speakers
US2684068A (en) * 1951-02-21 1954-07-20 Sindey R Orens Syringe

Cited By (54)

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US3931815A (en) * 1973-08-29 1976-01-13 Jintan Terumo Company, Ltd. Assembly having an adapter and a holder with a double ended needle
US4507117A (en) * 1983-07-11 1985-03-26 Vining Herbert C Syringe apparatus with retractable needle
US4732302A (en) * 1985-07-25 1988-03-22 Muehlbauer Ernst Device for the metered discharge of dental material
US4592744A (en) * 1985-08-14 1986-06-03 The University Of Virginia Alumni Patents Foundation Self-resheathing needle assembly
US4650468A (en) * 1986-02-26 1987-03-17 Jennings Jr Baldwin P Medical syringe
US4846811A (en) * 1987-01-29 1989-07-11 International Medical Innovators, Inc. Sliding sheath for medical needles
US4874384A (en) * 1987-07-13 1989-10-17 International Medical Innovators, Inc. Needle safety guard
US5154699A (en) * 1988-03-01 1992-10-13 Ryan Medical, Inc. Safety winged needle device for use with fistulas
US5019043A (en) * 1988-08-05 1991-05-28 Vincent Miguel Segui Pastor Syringe with needle retraction capability
US4969877A (en) * 1988-10-19 1990-11-13 The Pascall Medical Corporation Syringe
US4915699A (en) * 1988-10-19 1990-04-10 Elliot Kornberg Syringe
US6878131B2 (en) 1988-12-14 2005-04-12 Inviro Medical Devices, Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US4935015A (en) * 1988-12-14 1990-06-19 Hall John E Syringe apparatus with retractable needle
US6033386A (en) * 1988-12-14 2000-03-07 Inviro Medical Devices, Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5263933A (en) * 1988-12-14 1993-11-23 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US6117113A (en) * 1988-12-14 2000-09-12 Inviro Medical Devices Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US20050192541A1 (en) * 1988-12-14 2005-09-01 Inviro Medical Devices Limited Safety syringe needle device with interchangeable and retractable needle platform
US5520649A (en) * 1988-12-14 1996-05-28 Inviro Medical Devices Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5415638A (en) * 1988-12-14 1995-05-16 Inviro Medical Devices, Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5462531A (en) * 1988-12-14 1995-10-31 Inviro Medical Devices Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5380296A (en) * 1990-07-27 1995-01-10 Sterling Winthrop Inc. Multi-celled safety package, needle guard and safe disposal module for pre-filled medication cartridges
US5372590A (en) * 1990-07-27 1994-12-13 Habley Medical Technology Corporation Multi-celled safety package, needle guard and safety disposal module with sleeve for prefilled medication cartridges
US5324272A (en) * 1990-07-27 1994-06-28 Sterling Winthrop Inc. Multiple-celled safety package, needle guard and safe disposal module for prefilled medication cartridge
US5346474A (en) * 1991-11-06 1994-09-13 Design & Engineering Associates Disposable safety syringe
US5188601A (en) * 1991-11-06 1993-02-23 King Richard J Disposable safety syringe
US5879338A (en) * 1993-08-23 1999-03-09 Mahurkar; Sakharam D. Needle-syringe assembly for guidewire insertion
US6500129B1 (en) 1993-08-23 2002-12-31 Sakharam D. Mahurkar Hypodermic needle assembly
US5836921A (en) * 1993-08-23 1998-11-17 Mahurkar; Sakharam D. Hypodermic needle assembly
US5685862A (en) * 1993-08-23 1997-11-11 Mahurkar; Sakharam D. Hypodermic needle assembly
US5891105A (en) * 1993-08-23 1999-04-06 Mahurkar; Sakharam D. Hypodermic needle assembly
US6280401B1 (en) 1993-08-23 2001-08-28 Sakharam D. Mahurkar Hypodermic needle assembly
US5514100A (en) * 1993-08-23 1996-05-07 Mahurkar; Sakharam D. Hypodermic needle assembly
US5338311A (en) * 1993-08-23 1994-08-16 Mahurkar Sakharam D Hypodermic needle assembly
US5484421A (en) * 1993-08-30 1996-01-16 Smocer; Anthony V. Safety syringe
US6117112A (en) * 1997-11-18 2000-09-12 Mahurkar; Sakharam D. Single-use safety syringe
US6183464B1 (en) 1998-06-01 2001-02-06 Inviro Medical Devices Ltd. Safety syringe with retractable needle and universal luer coupling
US7252671B2 (en) * 1998-08-14 2007-08-07 Kyphon Inc. Systems and methods for treating vertebral bodies
US6641587B2 (en) 1998-08-14 2003-11-04 Kyphon Inc. Systems and methods for treating vertebral bodies
US20040049203A1 (en) * 1998-08-14 2004-03-11 Kyphon Inc. Systems and methods for treating vertebral bodies
US6699214B2 (en) 2000-01-19 2004-03-02 Scimed Life Systems, Inc. Shear-sensitive injectable delivery system
US20040147873A1 (en) * 2000-01-19 2004-07-29 Gellman Barry N Shear-sensitive injectable delivery system
US8845580B2 (en) 2000-01-19 2014-09-30 Boston Scientific Scimed, Inc. Shear-sensitive injectable delivery system
WO2001052923A1 (en) * 2000-01-19 2001-07-26 Scimed Life Systems, Inc. Shear-sensitive injectable delivery system
WO2002017801A3 (en) * 2000-07-14 2002-08-29 Kyphon Inc Systems and methods for treating vertebral bodies
WO2002017801A2 (en) * 2000-07-14 2002-03-07 Kyphon Inc. Systems and methods for treating vertebral bodies
US7481797B2 (en) 2001-11-28 2009-01-27 Mahurkar Sakharam D Retractable needle single use safety syringe
MD3048C2 (en) * 2004-03-01 2006-12-31 Анатол БАТЫР Syringe-ampoule
US7918821B2 (en) 2009-05-05 2011-04-05 Mahurkar Sakharam D Universal safety syringe
JP2013507216A (en) * 2009-10-16 2013-03-04 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Arrangement for use in a drug delivery device
WO2015134307A1 (en) * 2014-03-04 2015-09-11 Merck Sharp & Dohme Corp. Prefilled disposable injection device
US20170007766A1 (en) * 2014-03-04 2017-01-12 Merck Sharp & Dohme Corp. Prefilled disposable injection device
US10155088B2 (en) * 2014-03-04 2018-12-18 Merck Sharp & Dohme Corp. Prefilled disposable injection device
US11439768B2 (en) * 2019-07-17 2022-09-13 Wagner Florexil Compartmentalized syringe for combined medicine and flush solution

Also Published As

Publication number Publication date
FR1137565A (en) 1957-05-31
BE541390A (en)
GB815749A (en) 1959-07-01
CH340314A (en) 1959-08-15

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