US20150157815A1 - Substance source - Google Patents
Substance source Download PDFInfo
- Publication number
- US20150157815A1 US20150157815A1 US14/624,901 US201514624901A US2015157815A1 US 20150157815 A1 US20150157815 A1 US 20150157815A1 US 201514624901 A US201514624901 A US 201514624901A US 2015157815 A1 US2015157815 A1 US 2015157815A1
- Authority
- US
- United States
- Prior art keywords
- spout
- dispenser
- outer enclosure
- container
- counter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0076—Mechanical counters having a display or indicator on a drum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0075—Mechanical counters having a display or indicator on a disc
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
- G06M1/00—Design features of general application
- G06M1/04—Design features of general application for driving the stage of lowest order
- G06M1/041—Design features of general application for driving the stage of lowest order for drum-type indicating means
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
- G06M1/00—Design features of general application
- G06M1/04—Design features of general application for driving the stage of lowest order
- G06M1/045—Design features of general application for driving the stage of lowest order for dial, pointer, or similar type indicating means
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
- G06M1/00—Design features of general application
- G06M1/08—Design features of general application for actuating the drive
- G06M1/083—Design features of general application for actuating the drive by mechanical means
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06M—COUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
- G06M1/00—Design features of general application
- G06M1/22—Design features of general application for visual indication of the result of count on counting mechanisms, e.g. by window with magnifying lens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/123—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated reservoirs
Abstract
A source of gaseous, gas borne or droplet substance having: an inner pressurised container (1), a substance-release valve (2) device sealed across an end of the container (1), a spout (4) displaceable inwards of the container (1) against a spring of the valve (2) device for substance release; the source also includes: an outer enclosure enclosing the inner container along its length (12), at least partially its end (14) remote from the spout (4) and partially at its spout end (19), the outer enclosure ADN the inner container (1) being arranged to react force for displacement of the spout (4) on substance release; a counter (20) accommodated within the outer enclosure for counting substance release displacements of the spout (4); and a window (22) in the outer enclosure for viewing the count of the counter (20).
Description
- This application is a divisional of U.S. application Ser. No. 11/667,957 (published as U.S. 2008-0135576A1), filed May 17, 2007 (pending), which is a U.S. national phase of International Application PCT/GB2005/004430, filed 17 Nov. 2005, which designated the U.S. and claims priority of GB 0425518.8, filed 19 Nov. 2004, the entire contents of each of which are hereby incorporated by reference.
- The present invention relates to provided a source of a gaseous, gas borne or droplet substance.
- Such sources are used for dispensing medicaments in metered doses via a dispenser. There is an increasing desire for the number of doses dispensed and/or left in the source to be counted, so that a user can know the number of doses remaining before a fresh source (and dispenser) is required.
- The object of the present invention is to provide a substance source with an integral counter.
- According to a first aspect of the invention there is provided a source of a gaseous, gas borne or droplet substance having:
-
- an inner pressurised container,
- a substance-release valve device sealed across an end of the container,
- a spout displaceable inwards of the container against a spring of the valve device for substance release,
the source also including: - an outer enclosure enclosing the inner container along its length, at least partially across its end remote from the spout and partially at its spout end,
- the outer enclosure and the inner container being arranged to react force for displacement of the spout on substance release;
- a counter accommodated within the outer enclosure for counting substance release displacements of the spout; and
- a window in the outer enclosure for viewing the count of the counter.
- In certain embodiments, the counter is arranged at the end of the outer enclosure, for reacting and counting occurrences of spout-displacement force from the inner container to the outer enclosure. In particular where the substance is a high value medicament, the counter can be a single use electronic counter. However, since an electronic counter is a relatively expensive component of a medicament source, in the preferred embodiment with such a counter, it can be a multi-use electronic counter, with the outer enclosure being provided with a frangible enclosure for the counter, whereby the counter can be removed from the medicament source by breaking the enclosure when it is has reached its normal dose count limit, reset and installed on a fresh source using its fresh frangible closure. In this case, the counter provides the sole abutment for the inner container as regards spout-displacement force, whereby residual medicament cannot be used once the counter has been removed.
- Again, the counter can be a removable or an irremovable mechanical counter. The mechanical counter can include a dual set of ratchet teeth and pawls, with angular incrementation determined by the ratchet teeth and can be housed within the outer enclosure and gearing is provided between an incremented ratchet disc and an indicator disc viewable through the window in the outer enclosure. This avoids unreliable dosing with the container being nearly empty.
- In other embodiments, the counter is arranged to be incremented by displacement of the spout. Normally such a counter will be a mechanical counter including a rotatable member indexed by one increment on each displacement of the spout.
- Such a mechanical counter can include a dual set of ratchet teeth and pawls, one of either of the teeth and the pawls being displaced with the spout the other being fast with the outer enclosure and the rotatable member being incremented partially by one of the dual set of teeth on inwards displacement of the spout and partially by the other of the dual set of teeth on return outwards displacement of the spout.
- Alternatively, the mechanical counter can include a single set of ratchet teeth and at least one pawl and a frictional member restraining the rotatable member, one of either of the teeth and the pawls being displaced with the spout the other being fast with the outer enclosure and the rotatable member being incremented by the pawl and teeth on inwards displacement of the spout and held by the frictional member on return outwards displacement of the spout.
- In one of these embodiments:
-
- the rotatable member is a portion of the inner pressurised container or a sleeve fast with the container, the container or the sleeve being adapted to be indexed by one increment on each displacement of the spout,
- the said portion or sleeve has a helical track,
- the window extends axially and/or circumferentially of the outer enclosure and
- the source includes an indicator adapted to co-operate with the helical track for indicating movement along the extent of the window.
- Alternatively:
-
- the rotatable member is a member internal of the outer enclosure, extending around the inner container and having a helical track,
- the window extends axially and/or circumferentially of the outer enclosure and
- the source includes an indicator adapted to co-operate with the helical track for indicating movement along the extent of the window.
- In this alternative, the indicator can have:
-
- a curved inner face engaging the rotatable member, both at the track for movement of the indicator and laterally for location of the indicator and
- a flat outer face engaging the window with lateral extent for locating the indicator in the window circumferentially of the outer enclosure.
- Again the indicator can have:
-
- a plain inner face engaging the helical track,
- a sprung outer face engaging the window and
- sides for locating the indicator in the window circumferentially of outer enclosure and
the window is provided at a groove with sides co-operating with the sides of the indicator in locating the indicator circumferentially of the outer enclosure.
- Thirdly, the indicator and the outer enclosure can have a complementary non-circular cross-section for locating the indicator in the window circumferentially of the outer enclosure.
- It is possible for one of the sets of teeth and pawl(s) or the frictional member, whichever is provided, is arranged at the end of the inner member having the helical track remote from the spout and co-operates with the end of the outer enclosure on incrementing of the inner member. However, usually, both sets of teeth and pawls are provided at the spout end of the outer enclosure.
- The member having the helical track can essentially comprise the helical track along the extent of the track and around the inner container and is resilient for movement of its spout end with the spout. However, usually, the member having the helical track comprises a circular cylindrical member around the inner container. The helical track itself can be a channel or groove in the cylindrical member. Alternatively, the helical track can be a rib or ridge on the cylindrical member.
- In another feature, the member having the helical track, the indicator and the window are all adapted for plunging movement of the member and the indicator with the spout, a return spring being provided for return movement on outwards movement of the member and indicator after inwards, dispensing movement. Alternatively, the member having the helical track is axially located with respect to the outer enclosure and a separate member plungeable with respect to the outer enclosure is provided, the plungeable member being adapted for driving the helical track member in rotation.
- Preferably, wherein the plungeable member is provided with:
-
- means for irrotationally locating it with respect to the outer enclosure and
- ones of the pawls or the teeth for rotationally driving the helical track member, the others of the teeth or the pawls being provided on the helical track member.
In this case, the pawls can be resilient axially of the helical track member for return of the plungeable member.
- Alternatively the plungeable member can be provided with:
-
- the ones of the pawls or the teeth for rotationally driving the plungeable member, the outer enclosure being provided with the others of the teeth or the pawls,
- a plungeable connection with the helical track member for rotation thereof and
- a return spring for return movement of the plungeable member on outwards movement of the spout after inwards, dispensing movement.
- Again, the helix of the helical track can be regular. Alternatively the helix of the helical track can be less steep in its portion occupied by the indicator on initial use of the source and steeper in its portion indicating imminent exhaustion of the source.
- In accordance with an importance feature, the source includes an end cap of the outer enclosure at its end remote from the spout, the end cap being connected to an outer sleeve of the enclosure, at a position such that dispensing operation of the spout and incrementing operation of the counter are synchronised.
- In accordance with a second aspect of the invention there is provided a source of a gaseous, gas borne or droplet substance an inner subassembly and an outer subassembly,
-
- the inner subassembly having:
- an inner pressurised container,
- a substance-release valve device sealed across an end of the container,
- a spout displaceable inwards of the container against a spring of the valve device for substance release,
- the inner subassembly having an overall length from the distal end of the spout to the remote end of the container, which length decreases on substance release and having at least:
- a first quiescent length and
- a second length at which the valve is opened for substance release;
- the inner subassembly having an overall length from the distal end of the spout to the remote end of the container, which length decreases on substance release and having at least:
- the outer subassembly having:
- an outer enclosure at least partially enclosing the inner container along its length,
- an enclosure cap across the end of the enclosure remote from the spout and at least partially at its spout end,
- the enclosure cap and the inner container being arranged to react force for displacement of the spout on substance release;
- a counter accommodated within the outer enclosure for counting substance release displacements of the spout; and
- a counter actuation member arranged beside the spout for displacement inwards to increment the counter
- the outer subassembly having an overall length from the actuation member at the spout to a pressurised-container reaction surface, which length decreases on substance release and having at least:
- a first quiescent length and
- a second length at which counter incrementation is initiated,
- the outer subassembly having an overall length from the actuation member at the spout to a pressurised-container reaction surface, which length decreases on substance release and having at least:
- the subassembly also having:
- a tolerance adjusted connection of the cap to the outer enclosure set with respect to a use installation of the source, whereby the stroke between the first and second lengths of the respective assemblies is compensated for synchronisation of substance release and count incrementation.
- the inner subassembly having:
- According to a third aspect of the invention, there is provided a dispenser for a gaseous, gas borne or droplet substance, the dispenser comprising:
-
- a source of the first or second aspect;
- a mouth piece in connected to the outer enclosure;
- a junction member receiving the spout of the source;
- a nozzle connected to the junction member and arranged to direct a dose of the substance out through the mouth piece; and
- means for actuating the dispenser to dispense the dose and increment the counter.
- Normally the valve mechanism will be a metered dose valve mechanism.
- To help understanding of the invention, a specific embodiment thereof will now be described by way of example and with reference to the accompanying drawings, in which:
-
FIG. 1 is a partially sectioned side view of a first medicament source according to the invention; -
FIG. 2 is a top end view of the source ofFIG. 1 ; -
FIG. 3 is a view similar toFIG. 1 of a second source of the invention; -
FIG. 4 is a top view of the source ofFIG. 3 ; -
FIG. 5 is a side view of a third source of the invention; -
FIG. 6 is a top view of the source ofFIG. 4 ; -
FIG. 7 is a more detailed view of the mechanical counter of the third source; -
FIG. 8 is a s sectional view on the line VII-VII inFIG. 7 of the epicyclic gearbox of the counter ofFIG. 7 ; -
FIG. 9 is side partially sectioned side view of a fourth source of the invention; -
FIG. 10 is a plain side view of the fourth source; -
FIG. 11 is a partially sectioned side view of a first variant of the fourth source; -
FIG. 12 is a similar view of a second variant of the fourth source; -
FIG. 13 is a side view of a fifth source of the invention; -
FIG. 14 is a cross-sectional side view of the fifth source; -
FIG. 15 is a cross-sectional plan view of the fifth source; -
FIG. 16 is a scrap view of the teeth and pawls of the fifth source; -
FIG. 17 is a cross-sectional side view of a sixth source; -
FIG. 18 is a scrap view of a plunging connection the sixth source; -
FIG. 19 is a side view of the sixth source; -
FIG. 20 is a cross-sectional side view of a dispenser of the invention incorporating a source of the disclosure; and -
FIG. 21 is a cross-sectional plan view of the dispenser ofFIG. 20 . - In the first embodiment, the medicament source shown in
FIGS. 1 & 2 has: -
- an inner pressurised
container 1 of stamped aluminium, - a substance-
release valve device 2 sealed across an end of the container by means of acrimp cap 3, - a
spout 4 displaceable inwards of the container against aspring 23 of the valve device for release substance.
These features are conventional.
- an inner pressurised
- In accordance with the invention, the source also includes an
outer sleeve 11 enclosing the inner container along itslength 12, across itsend 14 remote from the spout and at least partially at itsspout end 15. Inthis embodiment, the sleeve also is of stamped aluminium, with a circularlycylindrical body 16, aclosed end 17 and anopen end 18 at which it has a turned-inrim 19, captivating the imler container in the outer sleeve by engagement under the crimp cap. Only thespout 4 extends from the outer sleeve. - Between the
end 14 of the inner container opposite from thespout 4 and theend 17 of the outer sleeve is accommodated anelectronic counter 20, of the type which increments or more precisely decrements each time a compressive force is applied across it. The counter per se is of a known type. It has adisplay 21 aligned with awindow 22 in theend 17 of the outer sleeve. - In use, with the spout received in the junction member of an inhaler body (not shown), pressure on the
end 17 of the outer sleeve urges it and the inner container down, with the spout being pushed inwards and causing the valve to release a dose through the junction member. - The force to actuate the valve is transmitted from the outer sleeve to the inner container via the counter, which decrements its display. Thus the user can monitor how many doses remain in the source by viewing the display through the
window 22. - Turning now to a second embodiment shown in
FIGS. 3 & 4 , whilst the previous embodiment is suitable for high value medicaments, it is not suitable for low value medicaments where the counter may be the most expensive component including the medicament. In this embodiment, thecounter 101 is removable and equipped with aswitch 102 which turns on the counter only when pressed in and resets the counter in doing so. - Whereas the
outer sleeve 103 of the first embodiment is of aluminium, that of the second embodiment is a two part plastics material moulding, suitably of polypropylene. It comprises asleeve component 104 and anend cap component 105. They havecomplementary formations lower rim 108 andinternal formations 109 for clipping into thecrimp neck 6 of the inner container, which is identical to that of the first embodiment—hence use of the same reference numerals in this respect. The formations discourage removal of the sleeve, but are provided with clearance from the crimp neck, whereby actuation for medicament dispensing always results in dispensing force application to the sleeve via thecounter 101. The sleeve is of sufficient length to discourage use of the source without thecap 105 fitted, in that theend 14 of the inner container is not readily accessible through the open end of the sleeve. - With a
counter 101 fitted in the open end and thecap 105 fitted, theend 14 of the inner container abuts against the counter and the counter abuts against the cap, at least on pressure on the cap for use of the source. Fitting of the counter and cap has switched on the counter, whose display is visible through awindow 110 in the cap. Pressing on thecap 105 or indeed the counter via its window results in (1) force being transmitted to the inner container for valve actuation and dose dispensing and (2) the dispensing act being counted. - The
sleeve formation 106 has a groove on the outer surface of the sleeve and thecap formation 107 has an inwards-facing rim on tear-off,annular strip 111. When the source is exhausted, the strip is torn off, the counter removed for use with a new source and the rest of the source is discarded. - Turning now a third embodiment, shown in
FIGS. 5 to 8 , theouter sleeve 203 is also a two part component, comprising asleeve part 204 and a cap which is longer to accommodate amechanical counter 201, which is deeper than its electronic counterpart. It has an inner-container engagement member 2011, with arecess 2012 for tightly receiving thecontainer end 14 and threeresilient pawl members 2013 which curve shallowly curve around and away from the spout. They engage arotary ratchet member 2014 with oppositely directedratchet teeth teeth 2015 are complementary to thepawl members 2013, whilst theteeth 2016 are complementary torigid pawl teeth 2017 on thecap 205. It is anticipate that that themember 2011 will be held against rotation by thespout 4 of thecontainer 1; however, if need be it can be splined to thesleeve part 204. Dispensing of a dose causes the pawl members to drive the ratchet member around with theteeth teeth - To allow a count of 200 doses requires a circle of 200 ratchet teeth. This is difficult to achieve with an inner container of 23 mm, a typical size, since the pitch of the teeth is:
-
23×3.14/200=0.36 mm. - In this embodiment the teeth are set at a greater pitch, but there are less of them. Their effect is modified by an
epicyclic gearbox 2020. This comprises asun wheel 2021 integral with theratchet member 2014. It is arranged within anannular gear 2022 moulded integrally with thecap 205, with its teeth set inwards from theupper ratchet teeth 2016. Threeplanet wheels 2023 havingcentral bores 2024 are arranged between the sun wheel and the annular wheel. As the ratchet member and with it the sun wheel is ratcheted around, the planet wheels roll around with it. With a comparatively small sun wheel, several turns of it are required for complete traverse of the planet wheels around the gearbox. Acarrier 2025 haspins 2026 which extend down into the bores of the planet wheels. On its top surface, the carrier has graduations visible through awindow 2027 in the end cap. Thus the number of doses used/remaining can be determined by viewing the graduations, which successively pass the window. - Turning on now to the fourth embodiment of
FIGS. 9 and 10 , the source there shown has anouter sleeve 303 of aluminium, with aslot 330 extending along the greater part of its length. Immediately within the sleeve is asecondary sleeve 331 with ahelical groove 332. Anindicator 333 in the form of a disc with studs on either side engages with its studs in the slot and the groove. Thus as the secondary sleeve is turned, the indicator is moved along the slot. The helix is uneven, being steeper at the spout end of the outer sleeve, where initial doses show only small movement of the indicator, whereas dispensing of the final doses causes faster movement of the indicator. - The secondary sleeve is moved in a manner akin to the ratchet member of the preceding embodiment. At the spout end of the outer sleeve, it is crimped onto a
guide member 334 having three shortlongitudinal grooves 335, which guide ayoke 336, havingfingers 337 extending into the grooves. The ends of the grooves are closed 338 to captivate the yoke. The upper ends of the grooves are closed byprojections 339 that extend to the crimp cap of the inner container, locating it within the outer sleeve. The yoke has acentral bore 340 for thespout 4 and threeresilient pawl members 341, which are spaced between theprojections 339. The pawl members extend up to engage withteeth 342 provided on the bottom edge of the secondary sleeve. The top edge of this sleeve also hasteeth 343, which co-operate with fixedpawl teeth 344 on acap 345 crimped to the outer sleeve. - In use, the source is mounted in a dispenser body (not shown except for a junction J), with the spout engaged in a junction member. Depression of the source towards the junction member pushes the spout into the valve and the yoke also towards the valve. The
flexible pawls 341 are permanently engaged with thelower teeth 342, whatever the position of the yoke, and as the yoke is urged in towards the inner container, the pawls foreshorten, rotating the secondary sleeve. The upper teeth are indexed across the fixed pawl teeth. As the source is allowed to return after dispensing its dose, the resilient pawls continue to urge the secondary sleeve up against the fixed pawls, with the result that the sleeve is held against rotation. The resilient pawls ride over the lower teeth, setting themselves for the next dispensing action. On successive actions, the secondary sleeve moves progressively round, driving the indicator down theslot 330 as described above. - A first variant of the fourth embodiment, as shown in
FIG. 11 has distinct similarities to the previous embodiments, save that the function of the helical groove in the secondary sleeve is performed by ahelical groove 432 impressed in the wall of the inner container. The function of the upper teeth and the fixed pawls is performed by anelastomeric ring 444 pushed into an outer-sleeve cap 445. Then the function of the lower ratchet teeth is performed byteeth 442 impressed into thecrimp cap 3 of the inner container. Theresilient pawls 441 act on theteeth 442, progressively rotating the inner container with respect to the outer sleeve and driving anindicator 433 along aslot 430 in the outer sleeve. - The second variant, shown in
FIG. 12 , differs in that theyoke 546 is rotatably carried on the spout. The yoke is fast with ahelical member 550, which is formed as a progressively tighter winding. It carries anindicator 533, co-operating with aslot 530 in an outer sleeve. The helical member abuts against the closed end of the outer sleeve, to urge the yoke permanently downwards. The outer sleeve is crimped to a two partyoke drive member 534. The twoparts ratchet teeth fingers 537 which are arranged between these teeth. - As the source is depressed and the spout is driven inwards, the yoke is urged inwards against the resilience of the helical member. The
fingers 537 slide along the faces of theupper teeth 5341 and rotate the helical member. As the spout is released, the fingers move back and engage thelower teeth 5342, further rotating the helical member. The result is that the fingers come to rest indexed one by one pitch of the upper teeth—and indeed one pitch of the lower teeth—ready for the next depression of the spout. - In a non-illustrated embodiment, the moulded plastics material helix of
FIG. 12 can be replaced by a spring wire helix. - Turning now to the fifth embodiment, shown in
FIGS. 13 to 16 , the source there shown has a pressurisedcontainer 1, with aspout 4. As shown, the upper part of the container is visible through anouter sleeve 611 of transparent plastics material. This has aflat window 612, through which anindicator 613 can be viewed. The indicator has a flatfront face 614, which abuts the flat inside of the window. Rear face 615 of the indicator is curved to match the curvature of a helically groovedinner member 616. The indicator has arear protrusion 617 into thegroove 618. This arrangement not only connects the indicator to the groove, but also prevents the indicator from turning about the protrusion due to the curvature of the rear face. Further, the indicator is restrained from moving along the groove. Such movement would involve thefront face 614 moving out of alignment with the window. However, again the curved rear face restrains such movement. - The pitch of the
groove 618 is small at the end of the inner member remote from the spout, but increases at the spout end to alert the user that a new source will shortly be required. The arrangement for indexing theinner member 616 is a series oftriangular teeth 619 moulded on the inside of the outer sleeve and a pair of oppositely directedflexible pawl arms 620 withpawl elements 621 at their distal end moulded in a cut out 622 in the inner member. Arigid pawl member 623 and a rigid locator notch 624 are provided. In use, the pawl element on the spout side of theteeth 619 makes initial contact with a tooth, followed by contact by thepawl 623 with the neighbouring tooth. Continued movement of the inner brings a parallel portion of the rigid pawl between these two teeth. One return movement, the other flexible pawl continues the indexing movement which is completed by the next tooth coming to rest in the notch 624. This movement is initiated by a junction member, not shown, in which thespout 4 is received, abutting an in-turnedrim 625 of the inner member, whereby depression of thecontainer 1 and with it theouter sleeve 611 and itsteeth 619 releases a dose from the spout and performs the first part of the indexing as described. Areturn spring 626 is provided between therim 625 and thecrimp cap 3 of the container. - Other details of the source are that outer sleeve has a clipped on
rim 627 outside theinner rim 625 at the spout end. Further the sleeve has an end cap 628 welded on at 629 to close the other end of the sleeve and locate the container axially with respect to the sleeve. The relative position of the container and the sleeve are important, because the spout co-operates with elastomeric parts, the tolerance of whose position with respect to thecap 3 and the body of thecontainer 1 is not tight. The result is the possibility of the release of the dose not being synchronised with the incrementing of the counter. In other words either may occur without the other. This can be avoided by arranging the relative quiescent position of the spout and the rim such that on inwards movement of the stem to its release position, the inner member is stroked to its indexing position. This is achieved by (1) measuring the overall length of the container and spout in quiescent state from the spout's distal end to the container's remote end and (2) welding the end cap 628 to the sleeve with a consequently determined length between the outer face of therim 625 and outer face of the end cap with the rim not yet fitted. The result is that with thespring 626 holding thecontainer 1 against the end cap 628 and the inner member against theteeth 619, both at the notch 624 and other corresponding abutments 630 around themember 616, the spout protrudes with a determined amount from therim 625. Synchronisation of dose release and indexing are thus achieved. - The sixth embodiment of
FIGS. 17 to 19 differs in a few but significant details. Itsinner member 716 is axially located with respect to theouter sleeve 711 by means of abead 751 on the inner member engaging in agroove 752 in the outer sleeve. A plungingextension 753 of the inner member, having itsrim 725 with thespout 4 passing through it and the inner members pawls (not shown), hasfingers 754 in plunging mesh withfingers 755 on theinner member 716. Thus dispensing action plunges theextension 753 only with respect to theouter sleeve 711 without plunging of the marker as occurs in the fifth embodiment. - The
marker 756 is guided in ahelical channel 757 extending both along and around the outer sleeve, providing enhanced opportunity of accurate graduation (not shown). It has a pip (not shown) on its back side and twofingers 758, which are resilient a extend outwards when free, which urge the marker into engagement with the helical channel. It has acentral mark 759 - The seventh embodiment of
FIGS. 20 & 21 differs in that the source integrally includes amouthpiece 801 and anactuation button 802, including ajunction 803 receiving thespout 4 and having anozzle 804 directed out of the mouth piece.FIG. 20 is a cross-sectional side view of a dispenser of the invention, includingelements - The mouthpiece is moulded in a
piece 805 fitted in place of the clipped onrim 627 of the fifth embodiment. Themoulding 805 has anaperture 806 in which thebutton 802 is received. - A further difference is that whilst the
inner member 816 is circularly cylindrical, theouter sleeve 811 is non-circular. Themarker 856 is formed as a stirrup around the inner member and is restrained from moving around it by having a shape complementary to the outer sleeve.
Claims (17)
1. A dispenser for a gaseous, gas borne or droplet substance, the dispenser comprising:
a container of a gaseous, gas borne or droplet substance having:
an inner pressurised container for the substance,
a substance-release valve device sealed across an end of the inner pressurized container and having a spring,
a spout at a spout end of the inner pressurized container, which is displaceable inwards of the inner pressurized container against the spring of the valve device for substance release,
the container also including:
an outer enclosure enclosing the inner pressurized container along its length, at least partially across its end remote from the spout and partially at its spout end, the outer enclosure and the inner pressurized container being arranged to be capable of reacting to cause displacement of the spout inwards of the inner pressurized container for substance release;
a counter accommodated within the outer enclosure for counting substance release displacements of the spout;
a window in the outer enclosure for viewing the count of the counter;
a mouth piece;
a junction member receiving the spout of the source;
a nozzle connected to the junction member and arranged to direct a dose of the substance out through the mouth piece; and
means for actuating the dispenser to dispense the dose and increment the counter.
2. A dispenser as claimed in claim 1 , wherein the counter is arranged at an end of the outer enclosure, for transmitting spout-displacement force between the inner container and the outer enclosure and counting occurrences of such force.
3. A dispenser as claimed in claim 2 , wherein the counter is a single-use or multi-use electronic counter.
4. A dispenser as claimed in claim 2 , wherein the counter is a removable or irremovable mechanical counter.
5. A dispenser as claimed in claim 4 , wherein the mechanical counter includes a dual set of ratchet teeth and pawls, with angular incrementation determined by the ratchet teeth.
6. A dispenser as claimed in claim 1 , wherein the counter is arranged to be incremented on displacement of the spout, and the counter includes a rotatable member indexed by one increment on each displacement of the spout.
7. A dispenser as claimed in claim 6 , wherein the mechanical counter includes a dual set of ratchet teeth and pawls, one of either of the teeth and the pawls being displaced with the spout the other being fast with the outer enclosure and the rotatable member being incremented partially by one of the dual set of teeth on inwards displacement of the spout and partially by the other of the dual set of teeth on return outwards displacement of the spout, or
a single set of ratchet teeth and at least one pawl and a frictional member restraining the rotatable member, one of either of the teeth and the pawls being displaced with the spout the other being fast with the outer enclosure and the rotatable member being incremented by the pawl and teeth on inwards displacement of the spout and held by the frictional member on return outwards displacement of the spout.
8. A dispenser as claimed in claim 6 , wherein:
the rotatable member is a portion of the inner pressurised container or a sleeve fast with the container, the container or the sleeve being adapted to be indexed by one increment on each displacement of the spout, or the rotatable member is a member internal of the outer enclosure, extending around the inner pressurized container,
the rotatable member having a helical track,
the window extending axially and/or circumferentially of the outer enclosure, and
the container includes an indicator adapted to co-operate with the helical track which operates as an indicator by movement along the window.
9. A dispenser as claimed in claim 8 , wherein
the rotatable member has a curved surface; and
the indicator:
engages the helical track for movement of the indicator, and has
a curved inner face engaging the rotatable member at the helical track for location of the indicator circumferentially of the rotatable member, and
a flat outer face engaging the window for locating the indicator at the window circumferentially of the outer enclosure.
10. A dispenser as claimed in claim 8 , wherein the indicator and the outer enclosure have a complementary non-circular cross-section for locating the indicator in the window circumferentially of the outer enclosure.
11. A dispenser as claimed in claim 7 , wherein one of the sets of teeth and pawl(s) or the frictional member, whichever is provided, is arranged at the end of the rotatable member having the helical track remote from the spout and co-operates with the end of the outer enclosure on incrementing of the rotatable member.
12. A dispenser as claimed in claim 8 , wherein the rotatable member having the helical track comprises a circular cylindrical member around the inner pressurized container and the helical track is a channel or groove in the cylindrical member or a rib or ridge on the cylindrical member.
13. A dispenser as claimed in claim 12 , wherein the rotatable member having the helical track, the indicator and the window are all adapted for plunging movement of the member and the indicator with the spout, a return spring being provided for return movement on outwards movement of the member and indicator after inwards, dispensing movement.
14. A dispenser as claimed in claim 13 , wherein the rotatable member having the helical track is axially located with respect to the outer enclosure and a separate member plungeable with respect to the outer enclosure is provided, the plungeable member being adapted for driving the helical track member in rotation.
15. A dispenser as claimed in claim 12 , wherein the plungeable member is provided
with:
means for irrotationally locating it with respect to the outer enclosure; and
pawls or teeth for rotationally driving the rotatable member;
cooperating teeth or pawls respectively being provided on the rotatable member having the helical track.
16. A dispenser as claimed in claim 8 , wherein the helix of the helical track is regular, or the helix of the helical track is less steep in its portion occupied by the indicator on initial use of the source and steeper in its portion indicating imminent exhaustion of the container.
17. A dispenser as claimed in claim 1 , including an end cap of the outer enclosure at its end remote from the spout, the end cap being connected to an outer sleeve of the enclosure, at a position such that dispensing operation of the spout and incrementing operation of the counter are synchronised.
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GB2448112B (en) | 2007-01-16 | 2011-08-17 | Bespak Plc | Improvements in or relating to dispensing apparatus |
ES2416342T3 (en) | 2007-02-27 | 2013-07-31 | Ivax Pharmaceuticals Ireland | Measured dose inhaler |
GB0706999D0 (en) | 2007-04-11 | 2007-05-16 | Ivax Pharmaceuticals Ireland | Metered-dose inhaler |
GB2451225B (en) | 2007-05-15 | 2009-07-08 | Bespak Plc | Improvements in or relating to dispensing apparatus |
DE102007026560A1 (en) | 2007-06-08 | 2009-01-15 | Tecpharma Licensing Ag | Delivery device with axially movable indicator |
-
2004
- 2004-11-19 GB GBGB0425518.8A patent/GB0425518D0/en not_active Ceased
-
2005
- 2005-11-17 US US11/667,957 patent/US20080135576A1/en not_active Abandoned
- 2005-11-17 EP EP05812617.8A patent/EP1812895B1/en not_active Not-in-force
- 2005-11-17 PL PL05812617T patent/PL1812895T3/en unknown
- 2005-11-17 CN CN2005800469085A patent/CN101120366B/en not_active Expired - Fee Related
- 2005-11-17 BR BRPI0518349-9A patent/BRPI0518349A2/en not_active Application Discontinuation
- 2005-11-17 NZ NZ555252A patent/NZ555252A/en not_active IP Right Cessation
- 2005-11-17 WO PCT/GB2005/004430 patent/WO2006054083A1/en active Application Filing
- 2005-11-17 JP JP2007542093A patent/JP4975635B2/en active Active
- 2005-11-17 HU HUE05812617A patent/HUE032408T2/en unknown
- 2005-11-17 LT LTEP05812617.8T patent/LT1812895T/en unknown
- 2005-11-17 EP EP16187682.6A patent/EP3121766A1/en not_active Withdrawn
- 2005-11-17 CA CA2587640A patent/CA2587640C/en not_active Expired - Fee Related
- 2005-11-17 ES ES05812617.8T patent/ES2605042T3/en active Active
- 2005-11-17 DK DK05812617.8T patent/DK1812895T3/en active
- 2005-11-17 AU AU2005305701A patent/AU2005305701B2/en not_active Ceased
- 2005-11-17 PT PT58126178T patent/PT1812895T/en unknown
-
2007
- 2007-05-15 IL IL183231A patent/IL183231A/en not_active IP Right Cessation
- 2007-05-18 ZA ZA200704060A patent/ZA200704060B/en unknown
- 2007-12-13 HK HK07113607.1A patent/HK1108046A1/en not_active IP Right Cessation
-
2015
- 2015-02-18 US US14/624,901 patent/US20150157815A1/en not_active Abandoned
- 2015-02-18 US US14/624,927 patent/US9707360B2/en not_active Expired - Fee Related
-
2016
- 2016-12-06 CY CY20161101256T patent/CY1118358T1/en unknown
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11395888B2 (en) | 2017-02-14 | 2022-07-26 | Norton (Waterford) Limited | Inhalers and related methods |
US11559637B2 (en) | 2017-02-14 | 2023-01-24 | Norton (Waterford) Limited | Inhalers and related methods |
US11583643B2 (en) | 2017-02-14 | 2023-02-21 | Norton (Waterford) Limited | Inhalers and related methods |
US11793953B2 (en) | 2017-02-14 | 2023-10-24 | Norton (Waterford) Limited | Inhalers and related methods |
US11865247B2 (en) | 2017-02-14 | 2024-01-09 | Norton (Waterford) Limited | Inhalers and related methods |
US11896759B2 (en) | 2017-02-14 | 2024-02-13 | Norton (Waterford) Limited | Inhalers and related methods |
Also Published As
Publication number | Publication date |
---|---|
EP3121766A1 (en) | 2017-01-25 |
IL183231A (en) | 2013-07-31 |
US9707360B2 (en) | 2017-07-18 |
AU2005305701B2 (en) | 2010-09-23 |
JP4975635B2 (en) | 2012-07-11 |
AU2005305701A1 (en) | 2006-05-26 |
CA2587640A1 (en) | 2006-05-26 |
WO2006054083A1 (en) | 2006-05-26 |
CN101120366A (en) | 2008-02-06 |
HUE032408T2 (en) | 2017-09-28 |
NZ555252A (en) | 2010-11-26 |
CN101120366B (en) | 2013-08-14 |
LT1812895T (en) | 2016-11-25 |
CA2587640C (en) | 2014-05-13 |
JP2008520305A (en) | 2008-06-19 |
HK1108046A1 (en) | 2008-04-25 |
ES2605042T3 (en) | 2017-03-10 |
DK1812895T3 (en) | 2017-01-16 |
PT1812895T (en) | 2016-12-12 |
GB0425518D0 (en) | 2004-12-22 |
US20080135576A1 (en) | 2008-06-12 |
PL1812895T3 (en) | 2017-05-31 |
CY1118358T1 (en) | 2017-06-28 |
EP1812895B1 (en) | 2016-09-28 |
IL183231A0 (en) | 2007-08-19 |
ZA200704060B (en) | 2008-05-28 |
BRPI0518349A2 (en) | 2008-11-18 |
EP1812895A1 (en) | 2007-08-01 |
US20150157814A1 (en) | 2015-06-11 |
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