US20080103565A1 - Method and apparatus for treatment of cutaneous and subcutaneous conditions - Google Patents
Method and apparatus for treatment of cutaneous and subcutaneous conditions Download PDFInfo
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- US20080103565A1 US20080103565A1 US11/865,367 US86536707A US2008103565A1 US 20080103565 A1 US20080103565 A1 US 20080103565A1 US 86536707 A US86536707 A US 86536707A US 2008103565 A1 US2008103565 A1 US 2008103565A1
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Definitions
- This invention relates to methods and apparatus for the photothermal treatment of tissue and, more particularly, to methods and apparatus for treating cutaneous and subcutaneous conditions at depth.
- heated pads or plates or various forms of electromagnetic radiation including visible, infrared and microwave radiation, electricity, and ultrasound have previously been used for heating subdermal muscles, ligaments, bones and the like to, for example, increase blood flow, to otherwise promote the healing of various injuries and other damage, and for various therapeutic purposes, such as frostbite or hyperthermia treatment, treatment of poor blood circulation, physical therapy, stimulation of collagen, cellulite treatment, adrenergic stimulation, wound healing, psoriasis treatment, body reshaping, non-invasive wrinkle removal, etc.
- the heating of tissues has also been utilized as a potential treatment for removing cancers or other undesired growths, infections and the like. Heating may be applied over a small localized area, over a larger area, for example to the hands or feet, or over larger regions of tissue, including the entire body.
- optical radiation While optical and near infrared (NIR) radiation (collectively referred to hereinafter as “optical radiation” is generally both less expensive and, being non-mutagenic, safer than microwaves radiation, the use of optical radiation has heretofore not been considered suitable for most applications involving heating of tissue at depth, the term “tissue at depth” as used herein meaning tissue at the border zone of the dermis and hypodermis or subcutaneous region, some of which tissue may be in the lower dermis, mostly at a depth deeper than 1 mm, and tissue below this border zone to a depth of up to about 50 mm.
- tissue at depth as used herein meaning tissue at the border zone of the dermis and hypodermis or subcutaneous region, some of which tissue may be in the lower dermis, mostly at a depth deeper than 1 mm, and tissue below this border zone to a depth of up to about 50 mm
- tissue at depth as used herein meaning tissue at the border zone of the dermis and hypodermis or subcutaneous region, some of which
- this invention provides a method and apparatus for treating at least a selected target region at depth, as this term has previously been defined, of a patient's body, while protecting non-targeted tissue by utilizing a suitable mechanism to cool the patient's skin surface to a temperature below normal body temperature for a selected duration; utilizing a suitable mechanism to selectively apply radiation to the patient's skin above said region before, during and/or after cooling; and repeating the cooling and radiation application for a selected number of cycles, the temperature to which the patient's skin is cooled and the duration of cooling being sufficient to cool the treatment region to a selected temperature below normal body temperature during at least cooling portions of cycles.
- the cooling duration should be at least about 10 seconds, normally being between approximately 10 seconds and 20 minutes.
- the radiation may be applied for approximately one second to 4 minutes.
- the cooling may be performed continuously while the radiation is applied at intervals during the cooling.
- the selected temperature should be low enough to result in at least a selective phase change of at least a portion of the fat.
- the radiation should be of sufficient power and duration and of appropriate wavelength to heat the treatment region to at least a temperature where the phase of the fat cells is altered.
- the radiation may be of sufficient power and duration and of appropriate wavelength to heat the treatment region to a temperature where at least one of the biophysical and biochemical characteristics of cells in the region is altered.
- the radiation should be of sufficient power and duration and of appropriate wavelength to heat tissue above the treatment region to protect the tissue, but not to significantly heat the treatment region.
- the treatment involves cycling cooling and heating of the treatment region, radiation being applied after cooling and the radiation being of sufficient power and duration and of appropriate wavelength to heat the region to an appropriate temperature to effect the treatment.
- a selected condition of the patient is detected and utilized to control at least a portion of the operation. Stimulation of the selected region may also be utilized before, during and/or after at least one of the operations, such stimulation being generally at least one of mechanical, acoustic and electrical.
- the period and/or phase of the treatment cycles may be correlated with a sub-circadian rhythm of the patient.
- the radiation is from a continuous wave source and cooling is also performed from a substantially continuously operating source.
- cooling and radiation application are each performed by passing an applicator outputting the appropriate source over the patient's overlying the treatment region at a selected rate.
- the same applicator may be used to perform both cooling ad radiation application for these embodiments and the applicator my perform both operations during the same pass or separate passes.
- radiation is selectively delivered to the patients body above the selected region to heat the region; patient tissue above the selected region is concurrently cooled to a temperature below that of the selected region; and the region is cooled to a temperature below normal body temperature before and/or after the heating of the region.
- treatment is performed by cyclically applying radiation and cooling to the surface of the patient's skin above the selected region through at least one applicator providing substantially continuous cooling/radiation output, which applicator is passed over the patient's skin over the region multiple times for each cooling/radiation cycle.
- FIG. 1 is a diagram illustrating the temperature/depth profile of the skin and subcutis at various times after the onset of surface cooling
- FIG. 2 is a diagram illustrating temperature in the human body as a function of cooling time for various depths
- FIG. 3 is a diagram illustrating the onset time of patient discomfort and of patient pain as a function of skin surface temperature
- FIG. 4 is a schematic diagram of apparatus suitable for practicing the teachings of this invention.
- FIGS. 5 a - 5 d are diagrams illustrating cooling temperature (T cooling), heating temperature (T heating), temperature in an upper layer of the skin (T upper) and target temperature at depth (T target) relative to normal core body temperature (T core normal) for successive cooling/heating cycles in a protective mode;
- FIG. 6 a - 6 d are diagrams illustrating cooling temperature (T cooling), heating temperature (T heating), temperature in an upper layer of the skin (T upper) and target temperature at depth (T target) relative to normal core body temperature (T core normal) for successive cooling/heating cycles in a therapeutic mode;
- FIG. 7 is a diagram illustrating the hysterisis of optical transmittance in fat
- FIG. 8 a is a cut-away side view of an optical head suitable use in practicing the teachings of the invention.
- FIG. 8 b is an enlarged cut-away side view of a portion of the head shown in FIG. 8 a;
- FIG. 9 is a diagram illustrating temperature dynamics at different depth in the skin when in multi-scan mode using non-selective heating with the applicator shown in FIG. 8 ;
- FIG. 10 is a diagram illustrating temperature dynamics in blood vessels at different depths in the skin in multi-scan mode using non-selective heating with the applicator shown in FIG. 8 .
- inventions include the treatment of various pathological and cosmetic conditions, particularly skin rejuvenation, wrinkle removal, skin tightening and lifting, reduction of odor production, hair growth control, acne treatment, cellulite and subcutaneous fat treatment, physical therapy, muscle and skeletal treatments, including treatment of spinal cord problems, and treatment of cumulative trauma disorders (CTD's) such as carpel tunnel syndrome (CTS), tendonitis and bursitis, fibromyalgia, lymphedema and cancer therapy.
- CTD's cumulative trauma disorders
- CTS carpel tunnel syndrome
- tendonitis and bursitis fibromyalgia
- lymphedema lymphedema
- cancer therapy cumulative trauma disorders
- thermal energy either heating or cooling
- tissue may also be used, for example, in physical therapy treatments, such as to enhance or accelerate wound healing or relieve pain.
- Beneficial effects may include a decrease in joint stiffness, an increase in joint extensibility of collagenous structures such as tendons and scar tissue, pain relief, blood-flow changes, or a decrease in muscle spasm and increase in muscle tone.
- large protein molecules may have high absorption coefficients, and the heating of protein-rich collagenous tissues may contribute to healing.
- a wide variety of conditions may be treated using this invention, for example, but not limited to, strained tendons, tenosynovitis, torn ligaments, tendonitis, bursitis, torn joint capsules, or torn muscles.
- Thermal treatment can be effective on highly metabolic organs such as sebaceous gland, sweat glands and hair follicles. Other processes may be activated or deactivated within tissue during cooling or heating. Mechanical or electrical stimulation, such as massage, may also be used in conjunction with cooling or heating to achieve benefits greater then can be achieved by either alone. Positive and negative pressure may also be applied to the skin surface above the treatment region to facilitate the treatment.
- the present invention may be used for non-invasive or non-destructive reduction of localized fat deposits.
- the invention may be used to heat fat or adipose cells past their damage temperature, causing cell damage and/or necrosis.
- the treated cells may undergo apoptosis, resulting in cell death.
- the dead cells may then be removed or resorbed into the body, for example, by the body's phagocytic or lymphatic systems.
- Fat reduction may also be achieved by heating fat or adipose cells to an elevated temperature, but below the damage temperature.
- the fat cells may be heated to a temperature of between about 41° C. and about 45° C.
- lipolysis or the process of breaking down fat in the body, may be regulated by enzymes sensitive to temperature, such as HSL (“hormone-sensitive lipase”).
- HSL hormone-sensitive lipase
- elevating the temperature of the adipose cells may increase the lipolysis rate, and thus contribute to a reduction in subdermal fat in the area being treated. This temperature can be below the temperature for vascular/lymph damage so damaged fatty cells and fatty acids can be easily removed from the treatment region.
- application of the present invention may be used in combination with other fat-reduction techniques, such as medication, exercise, or adrenergic stimulation
- the invention also includes cooling of the fat tissue to a temperature below normal body temperature, and preferably below the phase transition temperature of at least some fraction of the lipid content of fatty cells, which temperature is substantially higher then the freezing temperature of water-containing tissue, preceded or preferably followed by heating the fat to a temperature below its damage threshold.
- Triglycerides which constitute the largest fraction of lipids in human fatty tissue
- ⁇ , ⁇ ′, and ⁇ can exist. These forms are (in the order of increasing stability): ⁇ , ⁇ ′, and ⁇ .
- the latter crystals are also significantly larger in size (as needle of a dozen microns length).
- Crystal formation can be the reason for fatty cell dysfunction and shrinkage resulting from mechanical stress on cell structure and/or destruction of cell metabolism.
- ⁇ crystal formation can the primer mechanism for fatty cell treatment.
- triglycerides are cooled from normal body temperature, formation of ⁇ -crystals takes place.
- ⁇ ′ first and ⁇ second reverse heating of the crystallized triglycerides is required. Further heating leads to complete melting of all crystalline forms.
- the following process is suggested to initiate formation of ⁇ -crystals in adipose cells.
- the fatty tissue is cooled to a lower-than-normal temperature T ⁇ (in the range between 0 and 37 C). This results in ⁇ -crystals being formed.
- the tissue is heated back to a temperature T ⁇ >T ⁇ but below 37 C, causing formation of ⁇ ′- and ⁇ -crystals.
- the tissue can be heated to even higher temperature in order to melt the crystals, and the process can be repeated for a selected number of cycles.
- the expected final result is dystrophy and decrease in volume of fatty tissue. This process takes place for all temperature range 0-37 but for lower T ⁇ this process is more effective.
- Thermal activation of lymph systems in subcutaneous fat can also be used to treat cellulite by removing proteins from extra cell spaces.
- FIG. 1 Application of a cooling panel (agent or device) to the skin surface causes the temperature of skin and the subcutaneous region or subcutis to drop gradually, as illustrated by FIG. 1 .
- curve ( 1 ) is after one minute
- curve ( 2 ) after five minutes
- curve ( 3 ) after ten minutes
- curve ( 4 ) after thirty minutes of application of a cooling panel to the skin surface.
- the depth of the skin/fat or dermis/subcutaneous boundary shown at 3 mm in FIG. 1 , will vary depending on a number of factors including the patient and the portion of the patient's body being treated.
- the rate of cooling and the final temperature depend on the depth of the target and the temperature of the skin surface.
- Substantial cooling of targets in the skin can be achieved in the time range between 10 s and 300 s. Deeper targets in subcutaneous fat need cooling times in the range between 2 min and 30 min. Cooling time can be shortened by simultaneously coupling into the skin pressure or acoustic waves or by intensive massage of cooled skin. The acoustic waves or mechanical massage can increase the heat conductivity of the skin and subcutaneous fat by forced convection of inter-cellular water.
- fatty and other tissues including, but not limited to:
- FIG. 3 illustrates the dependence of these onset times on the temperature at the skin surface. As a result, the practical application time may be insufficient to achieve a desired therapeutic effect.
- Thermal cycling comprised of cooling and heating phases, may be used to eliminate both the pain/discomfort and unwanted tissue damage outside the target region. It should be emphasized that, although methods and devices alternating skin surface temperature between hot and cold have previously been proposed, the thermal inertia of tissue prevents rapid propagation of a heat front from the skin surface to a desired treatment depth (or vice versa).
- This invention therefore uses deep-penetrating electromagnetic or acoustic radiation to create distributed heat sources within tissue. This allows increasing the treatment time substantially and achieving acceptable therapeutic effect, while maintaining both complete non-invasiveness of the procedure and patient comfort.
- Thermal cycling initiates a number of biophysical and biochemical responses at molecular, cellular, tissue, and organ levels, including (but not limited to):
- thermal cycling can be used for treatment of a wide range of conditions, involving skin, subcutaneous fat, connective tissues, blood and lymph vasculature, muscles, bones, and other internal organs.
- the cooling unit can be a thermoelectric element, an enclosure with cooling agent, a stream of cold gas (or liquid) or other cooling unit known in the art.
- Phase-changing materials can also be used for cooling.
- skin surface temperature during the cooling phase should be maintained within the range between 0 C and 25 C.
- tissue temperature on the heating phase is in the range between 25 C and 45 C.
- optical radiation is used on the heating phase of the cycle.
- the energy source can be a laser, an LED, a lamp (discharge, halogen or other), or a combination or an array thereof.
- the spectral composition of the source can be either narrow- or broad-band, with the range of wavelengths between 400 nm and 2000 nm. Spectral filtration can be used for further modifying spectral composition of the beam in order to achieve optimal penetration. The wavelengths used for a particular application will depend on the target tissue, the depth of the tissue and other factors.
- the light source is operated preferably in the continuous wave (CW) mode, with a preferred irradiance at the skin surface in the range between 0.1 and 100 W/cm2.
- the thermal cycle is organized in such a way as to maximize efficacy of treatment.
- duration of the cooling phase can be between 10 sec and 30 min, whereas duration of the heating phase can be between 1 sec and 4 min.
- the apparatus of FIG. 4 also includes a power supply for the energy source, a suitable control unit, an optional sensor, the function of which will be discussed later, and other components normally used in such apparatus.
- the invention can be practiced in two distinctive modes (See FIGS. 5 and 6 ): in the protective mode, thermal cycling is used to protect adjacent (typically, upper) tissue from unwanted damage; whereas in the therapeutic mode thermal cycling is used substantially as a treatment modality.
- the invention can be practiced in at least two distinct modes (See FIGS. 5 and 6 ).
- initially applied cooling rapidly lowers the temperature at the skin surface, the target region and all tissue therebetween.
- a heating phase is initiated.
- the radiation from the energy source is sufficient to raise the temperature at the skin surface and below to a depth above the treatment region to a temperature above a discomfort or damage temperature, but has little effect on the treatment region at depth. This results in the temperature of the treatment region continuing to drop slightly with successive cooling cycles.
- This mode of thermal cycling is thus used to protect adjacent (typically, upper) tissue from unwanted damage.
- thermal cycling is used substantially as a treatment modality.
- the cooling and radiation parameters are selected so that, during heating cycles, the temperature at both the surface and the treatment region rise above normal body temperature, the treatment region thus being cycled between cold therapy and heat therapy. While in FIG. 6 , the target region is heated above normal body temperature during heating portions of each cycle, this is not a limitation on the invention, and cyclically heating the target region to a selected temperature below normal body temperature may also have therapeutic effect for some conditions. Cycling may also be practiced by heating the target region to a temperature sufficient to cause hyperthermia, for example 42 to 47° C., either with or without simultaneous cooling to protect overlying tissue, and then either reducing or removing the radiation or increasing cooling to cool the treatment region below normal body temperature, this being done cyclically.
- hyperthermia for example 42 to 47° C.
- Thermal cycling offers another advantage when optical radiation is used as the deep-penetrating energy. Specifically, it has been demonstrated with optical measurements, that the rate of increase in optical transmittance when fresh human fatty tissue is heated exceeds the rate of decrease in optical transmittance when the same tissue is cooled (See FIG. 7 ). There is an indication of accumulated irreversible structural change in the fatty tissue caused by thermal cycling in relatively narrow temperature ranges between 25 and 30 C. As a consequence, the penetration depth of the optical radiation (and the efficiency of the heating phase) can be augmented by multiple cycling.
- the applicator (handpiece) of the apparatus can be realized as a stationary implement, which is placed on the treatment area prior to initiating thermal cycling.
- the handpiece can be manually or mechanically scanned along the skin surface (See FIG. 8 ).
- Thermal cycling can be performed concurrently with scanning.
- thermal cycling can be implemented by performing at least one (preferably, several) passes on the cooling phase, followed by at least one (preferably, several) passes on the heating phase, and repeating the cycle until desired treatment effect is achieved.
- FIG. 8 a an exemplary scanning handpiece is shown which includes a handle 1 and an applicator 2 . Referring to FIG.
- the applicator 2 includes a mount 3 , a reflector cooling fan 4 , an optional pressure or acoustic generator, vibrator or massaging implement 5 , a reflector 6 , a radiation source (an arc or halogen lamp for the embodiment shown) 7 , a cooling plate 8 , an optional wheel 9 functioning as a mechanical velocity sensor, a cooling agent 10 and an optical filter 11 .
- the apparatus of FIG. 8 can be used, in particular, in a multi-scan mode.
- the multi-scan mode results in non-uniform cycling of temperature at different depths.
- FIG. 9 shows temperature at the epidermis/dermis junction (0.1 mm depth), dermis/hypodermis junction (2.5 mm depth) and subcutaneous fat (7.5 mm depth) as a function of time for multi-scan operation. Calculations have been done for the following conditions: wavelength 800-1800 nm (filtered spectrum of halogen lamp), power density 80 W/cm2, width of optical beam across scanning direction is 1 cm, speed of scan is 10 cm/s, length of scan is 50 cm, temperature of cold sapphire window in contact with the skin is ⁇ 10° C.
- the temperature of the contact plate can be significantly lower than the skin freezing temperature and at fast scanning speeds (about 10 cm/s), can be as low as ⁇ 50° C. without risk of cold injury.
- FIG. 9 shows that the amplitude of thermal oscillations decreases with depth in skin.
- the time of stabilization of the temperature for deep targets can be long: 0.1 mm-100 s or 10 scans, 2.5 mm-5 min or 30 scans, 7.5 mm-15 min or 90 scans.
- FIG. 10 shows temperatures at the blood vessels in first plexus (0.015 mm diameter, 0.1 mm depth), second plexus (0.2 mm diameter, 2.5 mm depth), and subcutaneous fat (0.1 mm diameter, 7.5 mm depth) as a function of time for multi-scan operation. Calculations have been done for the following conditions: wavelength 400-1800 nm (filtered spectrum of halogen lamp), power density 65 W/cm2, width of optical beam across scanning direction is 1 cm, speed of scan is 10 cm/s, length of scan is 50 cm, temperature of cold sapphire window in contact with the skin is ⁇ 10° C.
- FIG. 10 shows that the amplitude of thermal oscillations in blood vessels is significant in the skin and negligible in the subcutaneous fat.
- the apparatus or device for various of the embodiments may be slid or scanned over the surface of the patient's skin to overlie successive treatment regions, the dwell time, and thus the treatment duration, for each such region being a function of the rate at which the device is moved.
- the device may be moved over each treatment region multiple times during a single treatment. Since the device will typically also include a skin cooling mechanism, concurrent heating and cooling is effected for each region as the device passes thereover.
- the device may also include a cooling mechanism ahead of the portion of the device under the energy source to pre-cool skin above the treatment region (see for example issued U.S. Pat. Nos. 6,273,884 and 6,511,475, which are incorporated herein by reference).
- V speed of sliding
- d is spot or aperture size in the direction of scanning
- T is interval between two consecutive passes through same spot.
- T 0 is the stationary mode treatment time for the organ/region being treated
- T should be less than the thermal relaxation time of the tissue being treated in the region at depth.
- the treatment time can be greater than the thermal relaxation time of the tissue being treated.
- any of the embodiments can include a contact sensor to assure good optical and thermal coupling, and systems operating in the sliding mode may also include one or more motion sensors to control radiation delivery, cooling and other functions dependent on scanning speed, to enhance system safety and for other reasons.
- the applicator may also include a massager, vibrator or other mechanical stimulation device, an ultrasonic or other acoustic stimulator or a DC or other suitable electrical stimulation source. It has been found that such mechanical or electrical stimulation is more effective when tissue temperature deviates from normal body temperature (i.e., for hot or cold tissue). Similarly, the effect of deep heating may be enhanced by massage or other stimulation because both heat and cold generally penetrates better in compressed skin and subdermal tissue. Thus, the combination of deep heating and mechanical or electrical stimulation may provide significantly better results then either one alone. Heating may also be enhanced by supplementing the optical heating with, for example electro-stimulation by AC/DC, or additional heating by RF, etc. Tensioning or pressure applied to the skin overlying the treatment region may also enhance treatment effect and decrease patient discomfort/pain sensation.
- While an optical radiation source has been utilized for preferred embodiments, other forms of electromagnetic radiation such as microwave or radio frequency radiation can be used on the heating phase of the cycle. Alternatively, acoustic energy can be used. Unless otherwise indicated, the term radiation, as used herein, shall refer to the output from all such sources. The power of the source utilized should be selected in order to maintain the temperature of the targeted tissue within the preferred range.
- the effectiveness of the invention may also be further increased by practicing a thermotolerance regimen.
- the magnitude of temperature deviations from normal skin surface temperature which a patient can tolerate increases gradually from cycle to cycle, permitting treatment temperatures, and thus treatment effectiveness to also be gradually increased from cycle to cycle.
- This mode allows further increasing protection of cutaneous tissues from unwanted damage.
- the period and phase of the thermal cycle may also be possible to correlate the period and phase of the thermal cycle with sub-circadian biological rhythms of the patient. Such combination can further optimize treatment results by using naturally occurring oscillations of biochemical activity in cutaneous and subcutaneous tissues. Furthermore, the temporal structure of the thermal cycling can deviate from simple harmonic oscillations and be comprised, for example, of several, or even an infinite number of harmonics.
- the cooling implement can be realized as a layer (film, wrap) placed over the treatment region and the irradiating applicator can be realized as a head scanned on top of the cooling implement. Thermal cycling is achieved as a result of multiple passes of the irradiating applicator.
- Some embodiments of the invention can incorporate a feedback loop between the applicator and the control unit.
- the feedback loop can incorporate a single or multiple sensors registering the state of the apparatus and the treatment area.
- a thermal sensor can be used to initiate the heating phase of the cycle when tissue temperature drops below a certain threshold, and initiate the cooling phase of the cycle when the temperature exceeds another threshold.
- Other sensor types include, but are not limited to, scanning speed sensors, contact sensors, pressure sensors, skin detectors, and skin response sensors.
- an additional stimulating implement can be integrated into the applicator (see FIG. 8 b ).
- the purpose of the implement is to optimize tissue structure and facilitate thermal cycling.
- the implement can be, for example, mechanical (knitting, rolling, or pulling action) or vacuum (negative/positive pressure in the treatment area).
- Other forms of tissue stimulation may also be utilized, for example, ultrasonic or other acoustic stimulation, or electrical stimulation.
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Abstract
Description
- This application is a continuation of U.S. patent application Ser. No. 10/465,757 now U.S. Pat. No. 7,276,058, filed Jun. 19, 2003 which claims priority to U.S. Patent Application Ser. No. 60/389,871, filed Jun. 19, 2002 entitled “Method And Apparatus For Treatment Of Cutaneous And Subcutaneous Conditions”, all of which are incorporated herein by reference in their entirety.
- 1. Field of the Invention
- This invention relates to methods and apparatus for the photothermal treatment of tissue and, more particularly, to methods and apparatus for treating cutaneous and subcutaneous conditions at depth.
- 2. Description of the Related Art
- The benefits of being able to raise and/or lower the temperature in a selected region of tissue for various therapeutic and cosmetic purposes has been known for some time. For instance, heated pads or plates or various forms of electromagnetic radiation, including visible, infrared and microwave radiation, electricity, and ultrasound have previously been used for heating subdermal muscles, ligaments, bones and the like to, for example, increase blood flow, to otherwise promote the healing of various injuries and other damage, and for various therapeutic purposes, such as frostbite or hyperthermia treatment, treatment of poor blood circulation, physical therapy, stimulation of collagen, cellulite treatment, adrenergic stimulation, wound healing, psoriasis treatment, body reshaping, non-invasive wrinkle removal, etc. The heating of tissues has also been utilized as a potential treatment for removing cancers or other undesired growths, infections and the like. Heating may be applied over a small localized area, over a larger area, for example to the hands or feet, or over larger regions of tissue, including the entire body.
- Since most of the techniques described above involve applying energy to tissue at depth through the patient's skin surface, peak temperature generally occurs at or near the patient's skin surface and decrease, sometimes significantly, with depth. Further, while microwaves or ultrasonic and other acoustic radiation have been used in the past, such radiation has had limited use because, particularly for microwaves, they may be potentially mutagenic, may potentially otherwise result in cell or systemic damage and, particularly for acoustic sources, are relatively expensive. They may also not be practical for large-area treatment.
- While optical and near infrared (NIR) radiation (collectively referred to hereinafter as “optical radiation” is generally both less expensive and, being non-mutagenic, safer than microwaves radiation, the use of optical radiation has heretofore not been considered suitable for most applications involving heating of tissue at depth, the term “tissue at depth” as used herein meaning tissue at the border zone of the dermis and hypodermis or subcutaneous region, some of which tissue may be in the lower dermis, mostly at a depth deeper than 1 mm, and tissue below this border zone to a depth of up to about 50 mm The reason why this radiation has not been considered suitable is because such radiation is both highly scattered and highly absorbed in surface layers of tissue, precluding significant portions of such radiation from reaching the tissue regions at depth to cause heating thereof. In view of the energy losses due to scattering and absorption, substantial optical (including NIR) energy must be applied in order for enough such energy to reach a region of tissues at depth to have a desired effect. However, such high energy can cause damage to the surface layers of tissue and pain/discomfort to the patient, making it difficult to achieve desired photothermal treatments in tissue regions at depth. For these reasons, optical radiation has heretofore had at most limited value for therapeutic and cosmetic treatments on tissue at depth.
- While heating or cooling of tissue at depth alone has proved useful for many treatments, the combination of heating and cooling applied intermittently to the skin surface (known as contrast therapy) is also known and has been suggested for skin improvement, pain relief, inflammation reduction, and healing of injury. Of particular importance is the application of these techniques for reducing subcutaneous fat deposits and treating cellulite (gynoid lipodystrophy). However, use of cooling or heating, either alone or in combination for treatment of conditions at depth, for example for skin improvement, cellulite improvement, fat reduction, and treatment of other conditions has been limited by the body's pain/discomfort tolerance and by the damage limits of treated organs and adjacent, especially cutaneous, tissue that need to be kept intact.
- A need therefore exists for improved method and apparatus for photothermal treatment of tissue regions at depth, and in particular for treatment of deep dermis and subcutaneous regions of tissue, which treatments provide improved treatment results, while both reducing patient pain and discomfort and protecting adjacent and other non-treatment tissue from damage.
- In accordance with the above, this invention provides a method and apparatus for treating at least a selected target region at depth, as this term has previously been defined, of a patient's body, while protecting non-targeted tissue by utilizing a suitable mechanism to cool the patient's skin surface to a temperature below normal body temperature for a selected duration; utilizing a suitable mechanism to selectively apply radiation to the patient's skin above said region before, during and/or after cooling; and repeating the cooling and radiation application for a selected number of cycles, the temperature to which the patient's skin is cooled and the duration of cooling being sufficient to cool the treatment region to a selected temperature below normal body temperature during at least cooling portions of cycles. The cooling duration should be at least about 10 seconds, normally being between approximately 10 seconds and 20 minutes. Where radiation is applied after cooling, the radiation may be applied for approximately one second to 4 minutes. The cooling may be performed continuously while the radiation is applied at intervals during the cooling. Where the selected region is subcutaneous fat, the selected temperature should be low enough to result in at least a selective phase change of at least a portion of the fat. In this case, the radiation should be of sufficient power and duration and of appropriate wavelength to heat the treatment region to at least a temperature where the phase of the fat cells is altered. Alternatively, the radiation may be of sufficient power and duration and of appropriate wavelength to heat the treatment region to a temperature where at least one of the biophysical and biochemical characteristics of cells in the region is altered. Alternatively, the radiation should be of sufficient power and duration and of appropriate wavelength to heat tissue above the treatment region to protect the tissue, but not to significantly heat the treatment region. For another embodiment, the treatment involves cycling cooling and heating of the treatment region, radiation being applied after cooling and the radiation being of sufficient power and duration and of appropriate wavelength to heat the region to an appropriate temperature to effect the treatment. For some embodiments, a selected condition of the patient is detected and utilized to control at least a portion of the operation. Stimulation of the selected region may also be utilized before, during and/or after at least one of the operations, such stimulation being generally at least one of mechanical, acoustic and electrical. The period and/or phase of the treatment cycles may be correlated with a sub-circadian rhythm of the patient.
- For some embodiments, the radiation is from a continuous wave source and cooling is also performed from a substantially continuously operating source. For these embodiments, cooling and radiation application are each performed by passing an applicator outputting the appropriate source over the patient's overlying the treatment region at a selected rate. The same applicator may be used to perform both cooling ad radiation application for these embodiments and the applicator my perform both operations during the same pass or separate passes.
- In accordance with another aspect of the invention, radiation is selectively delivered to the patients body above the selected region to heat the region; patient tissue above the selected region is concurrently cooled to a temperature below that of the selected region; and the region is cooled to a temperature below normal body temperature before and/or after the heating of the region.
- In accordance with still another aspect of the invention, treatment is performed by cyclically applying radiation and cooling to the surface of the patient's skin above the selected region through at least one applicator providing substantially continuous cooling/radiation output, which applicator is passed over the patient's skin over the region multiple times for each cooling/radiation cycle.
- Other advantages, novel features, and objects of the invention will become apparent from the following detailed description of the invention when considered in conjunction with the accompanying drawings, which are schematic and which are not intended to be drawn to scale. In the figures, each identical, or substantially similar component that is illustrated in various figures is represented by a single numeral or notation. For purposes of clarity, not every component is labeled in every figure, nor is every component of each embodiment of the invention shown where illustration is not necessary to allow those of ordinary skill in the art to understand the invention.
- Non-limiting embodiments of the present invention will be described by way of example with reference to the accompanying drawings in which:
-
FIG. 1 is a diagram illustrating the temperature/depth profile of the skin and subcutis at various times after the onset of surface cooling; -
FIG. 2 is a diagram illustrating temperature in the human body as a function of cooling time for various depths; -
FIG. 3 is a diagram illustrating the onset time of patient discomfort and of patient pain as a function of skin surface temperature; -
FIG. 4 is a schematic diagram of apparatus suitable for practicing the teachings of this invention; -
FIGS. 5 a-5 d are diagrams illustrating cooling temperature (T cooling), heating temperature (T heating), temperature in an upper layer of the skin (T upper) and target temperature at depth (T target) relative to normal core body temperature (T core normal) for successive cooling/heating cycles in a protective mode; -
FIG. 6 a-6 d are diagrams illustrating cooling temperature (T cooling), heating temperature (T heating), temperature in an upper layer of the skin (T upper) and target temperature at depth (T target) relative to normal core body temperature (T core normal) for successive cooling/heating cycles in a therapeutic mode; -
FIG. 7 is a diagram illustrating the hysterisis of optical transmittance in fat; -
FIG. 8 a is a cut-away side view of an optical head suitable use in practicing the teachings of the invention; -
FIG. 8 b is an enlarged cut-away side view of a portion of the head shown inFIG. 8 a; -
FIG. 9 is a diagram illustrating temperature dynamics at different depth in the skin when in multi-scan mode using non-selective heating with the applicator shown inFIG. 8 ; and -
FIG. 10 is a diagram illustrating temperature dynamics in blood vessels at different depths in the skin in multi-scan mode using non-selective heating with the applicator shown inFIG. 8 . - Applications in which the invention may be useful include the treatment of various pathological and cosmetic conditions, particularly skin rejuvenation, wrinkle removal, skin tightening and lifting, reduction of odor production, hair growth control, acne treatment, cellulite and subcutaneous fat treatment, physical therapy, muscle and skeletal treatments, including treatment of spinal cord problems, and treatment of cumulative trauma disorders (CTD's) such as carpel tunnel syndrome (CTS), tendonitis and bursitis, fibromyalgia, lymphedema and cancer therapy.
- The application of thermal energy, either heating or cooling, to tissue may also be used, for example, in physical therapy treatments, such as to enhance or accelerate wound healing or relieve pain. Beneficial effects may include a decrease in joint stiffness, an increase in joint extensibility of collagenous structures such as tendons and scar tissue, pain relief, blood-flow changes, or a decrease in muscle spasm and increase in muscle tone. As another example, large protein molecules may have high absorption coefficients, and the heating of protein-rich collagenous tissues may contribute to healing. A wide variety of conditions may be treated using this invention, for example, but not limited to, strained tendons, tenosynovitis, torn ligaments, tendonitis, bursitis, torn joint capsules, or torn muscles. Thermal treatment can be effective on highly metabolic organs such as sebaceous gland, sweat glands and hair follicles. Other processes may be activated or deactivated within tissue during cooling or heating. Mechanical or electrical stimulation, such as massage, may also be used in conjunction with cooling or heating to achieve benefits greater then can be achieved by either alone. Positive and negative pressure may also be applied to the skin surface above the treatment region to facilitate the treatment.
- In certain embodiments, the present invention may be used for non-invasive or non-destructive reduction of localized fat deposits. For example, the invention may be used to heat fat or adipose cells past their damage temperature, causing cell damage and/or necrosis. Alternatively, the treated cells may undergo apoptosis, resulting in cell death. The dead cells may then be removed or resorbed into the body, for example, by the body's phagocytic or lymphatic systems. Fat reduction may also be achieved by heating fat or adipose cells to an elevated temperature, but below the damage temperature. For example, the fat cells may be heated to a temperature of between about 41° C. and about 45° C. Under these conditions, applying heat to subcutaneous fat may activate lipases or metabolize lipids contained within the adipose tissue found within the subcutaneous fat layer, or blood flow may increase to the heated area. Additionally, “lipolysis,” or the process of breaking down fat in the body, may be regulated by enzymes sensitive to temperature, such as HSL (“hormone-sensitive lipase”). Thus, elevating the temperature of the adipose cells may increase the lipolysis rate, and thus contribute to a reduction in subdermal fat in the area being treated. This temperature can be below the temperature for vascular/lymph damage so damaged fatty cells and fatty acids can be easily removed from the treatment region. Additionally, application of the present invention may be used in combination with other fat-reduction techniques, such as medication, exercise, or adrenergic stimulation
- The invention also includes cooling of the fat tissue to a temperature below normal body temperature, and preferably below the phase transition temperature of at least some fraction of the lipid content of fatty cells, which temperature is substantially higher then the freezing temperature of water-containing tissue, preceded or preferably followed by heating the fat to a temperature below its damage threshold. Triglycerides (which constitute the largest fraction of lipids in human fatty tissue) undergo a series of phase transitions when their temperature changes from normal body temperature to either a lower or higher temperature. Specifically, several crystalline forms can exist. These forms are (in the order of increasing stability): α, β′, and β. The latter crystals are also significantly larger in size (as needle of a dozen microns length). Crystal formation can be the reason for fatty cell dysfunction and shrinkage resulting from mechanical stress on cell structure and/or destruction of cell metabolism. β crystal formation can the primer mechanism for fatty cell treatment. When triglycerides are cooled from normal body temperature, formation of α-crystals takes place. In order to produce more stable forms, β′ first and β second, reverse heating of the crystallized triglycerides is required. Further heating leads to complete melting of all crystalline forms.
- Therefore, the following process is suggested to initiate formation of β-crystals in adipose cells. First, the fatty tissue is cooled to a lower-than-normal temperature Tα (in the range between 0 and 37 C). This results in α-crystals being formed. Then, the tissue is heated back to a temperature Tβ>Tα but below 37 C, causing formation of β′- and β-crystals. Finally, the tissue can be heated to even higher temperature in order to melt the crystals, and the process can be repeated for a selected number of cycles. The expected final result is dystrophy and decrease in volume of fatty tissue. This process takes place for all temperature range 0-37 but for lower Tα this process is more effective. Thermal activation of lymph systems in subcutaneous fat can also be used to treat cellulite by removing proteins from extra cell spaces.
- Application of a cooling panel (agent or device) to the skin surface causes the temperature of skin and the subcutaneous region or subcutis to drop gradually, as illustrated by
FIG. 1 . InFIG. 1 , curve (1) is after one minute, curve (2) after five minutes, curve (3) after ten minutes, and curve (4) after thirty minutes of application of a cooling panel to the skin surface. The depth of the skin/fat or dermis/subcutaneous boundary, shown at 3 mm inFIG. 1 , will vary depending on a number of factors including the patient and the portion of the patient's body being treated. The rate of cooling and the final temperature depend on the depth of the target and the temperature of the skin surface.FIG. 2 shows the calculated temperature dynamics of the dermis-subcutis junction at 2.5 mm depth and in subcutaneous fat at 7.5 mm depth resulting from a constant surface temperature of 0° C. Substantial cooling of targets in the skin can be achieved in the time range between 10 s and 300 s. Deeper targets in subcutaneous fat need cooling times in the range between 2 min and 30 min. Cooling time can be shortened by simultaneously coupling into the skin pressure or acoustic waves or by intensive massage of cooled skin. The acoustic waves or mechanical massage can increase the heat conductivity of the skin and subcutaneous fat by forced convection of inter-cellular water. - Depending on the surface temperature and the duration of application, a number of processes can be initiated in the fatty and other tissues, including, but not limited to:
-
- Phase transitions in lipids;
- Changes in regulatory functions of the adipocyte. In particular, lower temperatures may suppress activity of Alpha2 receptors, which inhibit adenylate cyclase and cyclic AMP through Gi protein and thus decrease lypolisis rate. This can lead to long-term atrophy of fatty cells after cold exposure;
- Increase of ion concentration in intracellular water. Such an increase is caused by partial binding of free water in the course of fat crystallization. Transition of water into bound state has been demonstrated spectroscopically. As a result, concentration of ions in the remaining free water increases. Once the ion concentration exceeds a critical level, irreversible damage to the vital mechanisms of the cell can occur;
- Water crystallization in tissues;
- Induction of apoptosis;
- Tissue necrosis;
- Stimulation of thermogenesis
- Remodeling of vascular and lymph vessels;
- Temporal or permanent dysfunction of follicles, sebaceous and sweat glands.
- In practical use, cold exposure time is limited by the onset of unpleasant and, subsequently, painful sensations.
FIG. 3 illustrates the dependence of these onset times on the temperature at the skin surface. As a result, the practical application time may be insufficient to achieve a desired therapeutic effect. - Thermal cycling, comprised of cooling and heating phases, may be used to eliminate both the pain/discomfort and unwanted tissue damage outside the target region. It should be emphasized that, although methods and devices alternating skin surface temperature between hot and cold have previously been proposed, the thermal inertia of tissue prevents rapid propagation of a heat front from the skin surface to a desired treatment depth (or vice versa).
- This invention therefore uses deep-penetrating electromagnetic or acoustic radiation to create distributed heat sources within tissue. This allows increasing the treatment time substantially and achieving acceptable therapeutic effect, while maintaining both complete non-invasiveness of the procedure and patient comfort.
- Beneficial effects of thermal cycling are not limited to treatment of fatty tissue. Thermal cycling initiates a number of biophysical and biochemical responses at molecular, cellular, tissue, and organ levels, including (but not limited to):
-
- modulation of cell membrane's permeability and, therefore, inter-membrane transport and exchange between intra- and interstitial compartments;
- induction of thermo-mechanical stress in the target (for example, malignant) cells, leading to cell death through either necrosis or apoptosis;
- changes in elasticity and permeability of vessel walls;
- changes in blood rheology;
- stimulation of tissue regeneration, including new collagen generation in skin and subcutis;
- changes of toxin structure in the interstitial fluid making them amenable for easy removal by lymphatic systems.
- As a result, thermal cycling can be used for treatment of a wide range of conditions, involving skin, subcutaneous fat, connective tissues, blood and lymph vasculature, muscles, bones, and other internal organs.
- Apparatus for implementing the technical concept is illustrated by
FIG. 4 . This implementation is exemplary, and a suitable configuration can be easily derived by those skilled in the art for particular applications. The cooling unit can be a thermoelectric element, an enclosure with cooling agent, a stream of cold gas (or liquid) or other cooling unit known in the art. Phase-changing materials can also be used for cooling. Preferably, skin surface temperature during the cooling phase should be maintained within the range between 0 C and 25 C. Preferable tissue temperature on the heating phase is in the range between 25 C and 45 C. In one embodiment of the invention, optical radiation is used on the heating phase of the cycle. In this embodiment, the energy source can be a laser, an LED, a lamp (discharge, halogen or other), or a combination or an array thereof. The spectral composition of the source can be either narrow- or broad-band, with the range of wavelengths between 400 nm and 2000 nm. Spectral filtration can be used for further modifying spectral composition of the beam in order to achieve optimal penetration. The wavelengths used for a particular application will depend on the target tissue, the depth of the tissue and other factors. The light source is operated preferably in the continuous wave (CW) mode, with a preferred irradiance at the skin surface in the range between 0.1 and 100 W/cm2. The thermal cycle is organized in such a way as to maximize efficacy of treatment. Typically, duration of the cooling phase can be between 10 sec and 30 min, whereas duration of the heating phase can be between 1 sec and 4 min. The apparatus ofFIG. 4 also includes a power supply for the energy source, a suitable control unit, an optional sensor, the function of which will be discussed later, and other components normally used in such apparatus. - The invention can be practiced in two distinctive modes (See
FIGS. 5 and 6 ): in the protective mode, thermal cycling is used to protect adjacent (typically, upper) tissue from unwanted damage; whereas in the therapeutic mode thermal cycling is used substantially as a treatment modality. - The invention can be practiced in at least two distinct modes (See
FIGS. 5 and 6 ). In the protective mode ofFIG. 5 , initially applied cooling rapidly lowers the temperature at the skin surface, the target region and all tissue therebetween. Before the patient experiences pain or discomfort, and before thermal damage occurs outside the target region, a heating phase is initiated. The radiation from the energy source is sufficient to raise the temperature at the skin surface and below to a depth above the treatment region to a temperature above a discomfort or damage temperature, but has little effect on the treatment region at depth. This results in the temperature of the treatment region continuing to drop slightly with successive cooling cycles. This mode of thermal cycling is thus used to protect adjacent (typically, upper) tissue from unwanted damage. In the therapeutic mode shown inFIG. 6 , thermal cycling is used substantially as a treatment modality. Here, the cooling and radiation parameters are selected so that, during heating cycles, the temperature at both the surface and the treatment region rise above normal body temperature, the treatment region thus being cycled between cold therapy and heat therapy. While inFIG. 6 , the target region is heated above normal body temperature during heating portions of each cycle, this is not a limitation on the invention, and cyclically heating the target region to a selected temperature below normal body temperature may also have therapeutic effect for some conditions. Cycling may also be practiced by heating the target region to a temperature sufficient to cause hyperthermia, for example 42 to 47° C., either with or without simultaneous cooling to protect overlying tissue, and then either reducing or removing the radiation or increasing cooling to cool the treatment region below normal body temperature, this being done cyclically. - Thermal cycling offers another advantage when optical radiation is used as the deep-penetrating energy. Specifically, it has been demonstrated with optical measurements, that the rate of increase in optical transmittance when fresh human fatty tissue is heated exceeds the rate of decrease in optical transmittance when the same tissue is cooled (See
FIG. 7 ). There is an indication of accumulated irreversible structural change in the fatty tissue caused by thermal cycling in relatively narrow temperature ranges between 25 and 30 C. As a consequence, the penetration depth of the optical radiation (and the efficiency of the heating phase) can be augmented by multiple cycling. - In some embodiments, the applicator (handpiece) of the apparatus can be realized as a stationary implement, which is placed on the treatment area prior to initiating thermal cycling.
- In other embodiments, the handpiece can be manually or mechanically scanned along the skin surface (See
FIG. 8 ). Thermal cycling can be performed concurrently with scanning. Alternatively, thermal cycling can be implemented by performing at least one (preferably, several) passes on the cooling phase, followed by at least one (preferably, several) passes on the heating phase, and repeating the cycle until desired treatment effect is achieved. Referring toFIG. 8 a, an exemplary scanning handpiece is shown which includes ahandle 1 and anapplicator 2. Referring toFIG. 8 b, theapplicator 2 includes amount 3, areflector cooling fan 4, an optional pressure or acoustic generator, vibrator or massaging implement 5, areflector 6, a radiation source (an arc or halogen lamp for the embodiment shown) 7, acooling plate 8, anoptional wheel 9 functioning as a mechanical velocity sensor, acooling agent 10 and anoptical filter 11. - The apparatus of
FIG. 8 can be used, in particular, in a multi-scan mode. The multi-scan mode results in non-uniform cycling of temperature at different depths.FIG. 9 shows temperature at the epidermis/dermis junction (0.1 mm depth), dermis/hypodermis junction (2.5 mm depth) and subcutaneous fat (7.5 mm depth) as a function of time for multi-scan operation. Calculations have been done for the following conditions: wavelength 800-1800 nm (filtered spectrum of halogen lamp), power density 80 W/cm2, width of optical beam across scanning direction is 1 cm, speed of scan is 10 cm/s, length of scan is 50 cm, temperature of cold sapphire window in contact with the skin is −10° C. For scanning mode, the temperature of the contact plate can be significantly lower than the skin freezing temperature and at fast scanning speeds (about 10 cm/s), can be as low as −50° C. without risk of cold injury.FIG. 9 shows that the amplitude of thermal oscillations decreases with depth in skin. However, the time of stabilization of the temperature for deep targets can be long: 0.1 mm-100 s or 10 scans, 2.5 mm-5 min or 30 scans, 7.5 mm-15 min or 90 scans. -
FIG. 10 shows temperatures at the blood vessels in first plexus (0.015 mm diameter, 0.1 mm depth), second plexus (0.2 mm diameter, 2.5 mm depth), and subcutaneous fat (0.1 mm diameter, 7.5 mm depth) as a function of time for multi-scan operation. Calculations have been done for the following conditions: wavelength 400-1800 nm (filtered spectrum of halogen lamp), power density 65 W/cm2, width of optical beam across scanning direction is 1 cm, speed of scan is 10 cm/s, length of scan is 50 cm, temperature of cold sapphire window in contact with the skin is −10° C.FIG. 10 shows that the amplitude of thermal oscillations in blood vessels is significant in the skin and negligible in the subcutaneous fat. Large temperature oscillations at the vessels in the second plexus (up to 10° C.) can be effective for treatment of various conditions at the deep dermis and dermis/hypodermis junction and for improvement of cosmetic appearance of cellulite. Since the temperature of vessels in the subcutaneous fat is continuously rising, this treatment can be effective for increasing the rate of lypolysis. - Where energy source is a continuous wave (CW) or other long duration source, the apparatus or device for various of the embodiments may be slid or scanned over the surface of the patient's skin to overlie successive treatment regions, the dwell time, and thus the treatment duration, for each such region being a function of the rate at which the device is moved. The device may be moved over each treatment region multiple times during a single treatment. Since the device will typically also include a skin cooling mechanism, concurrent heating and cooling is effected for each region as the device passes thereover. The device may also include a cooling mechanism ahead of the portion of the device under the energy source to pre-cool skin above the treatment region (see for example issued U.S. Pat. Nos. 6,273,884 and 6,511,475, which are incorporated herein by reference). The power density Ps for this sliding mode of operation is:
P S =P 0 Tv/d, - Were P0 is power density for the organ/region being treated in a stationary mode
- V is speed of sliding,
- d is spot or aperture size in the direction of scanning,
- T is interval between two consecutive passes through same spot.
- Treatment time is
T S =T 0 Tv/d, - where T0 is the stationary mode treatment time for the organ/region being treated In order for the multiple passes to be beneficial, T should be less than the thermal relaxation time of the tissue being treated in the region at depth. However, when in either stationary mode or sliding mode, the treatment time can be greater than the thermal relaxation time of the tissue being treated.
- Any of the embodiments can include a contact sensor to assure good optical and thermal coupling, and systems operating in the sliding mode may also include one or more motion sensors to control radiation delivery, cooling and other functions dependent on scanning speed, to enhance system safety and for other reasons.
- In addition to coupling the deep heating treatment of this invention with deep cooling to enhance treatment of fat, bone, muscle, etc., the applicator may also include a massager, vibrator or other mechanical stimulation device, an ultrasonic or other acoustic stimulator or a DC or other suitable electrical stimulation source. It has been found that such mechanical or electrical stimulation is more effective when tissue temperature deviates from normal body temperature (i.e., for hot or cold tissue). Similarly, the effect of deep heating may be enhanced by massage or other stimulation because both heat and cold generally penetrates better in compressed skin and subdermal tissue. Thus, the combination of deep heating and mechanical or electrical stimulation may provide significantly better results then either one alone. Heating may also be enhanced by supplementing the optical heating with, for example electro-stimulation by AC/DC, or additional heating by RF, etc. Tensioning or pressure applied to the skin overlying the treatment region may also enhance treatment effect and decrease patient discomfort/pain sensation.
- While an optical radiation source has been utilized for preferred embodiments, other forms of electromagnetic radiation such as microwave or radio frequency radiation can be used on the heating phase of the cycle. Alternatively, acoustic energy can be used. Unless otherwise indicated, the term radiation, as used herein, shall refer to the output from all such sources. The power of the source utilized should be selected in order to maintain the temperature of the targeted tissue within the preferred range.
- The effectiveness of the invention may also be further increased by practicing a thermotolerance regimen. In this mode, the magnitude of temperature deviations from normal skin surface temperature which a patient can tolerate increases gradually from cycle to cycle, permitting treatment temperatures, and thus treatment effectiveness to also be gradually increased from cycle to cycle. This mode allows further increasing protection of cutaneous tissues from unwanted damage.
- It may also be possible to correlate the period and phase of the thermal cycle with sub-circadian biological rhythms of the patient. Such combination can further optimize treatment results by using naturally occurring oscillations of biochemical activity in cutaneous and subcutaneous tissues. Furthermore, the temporal structure of the thermal cycling can deviate from simple harmonic oscillations and be comprised, for example, of several, or even an infinite number of harmonics.
- In certain embodiments, the cooling implement can be realized as a layer (film, wrap) placed over the treatment region and the irradiating applicator can be realized as a head scanned on top of the cooling implement. Thermal cycling is achieved as a result of multiple passes of the irradiating applicator.
- Some embodiments of the invention can incorporate a feedback loop between the applicator and the control unit. The feedback loop can incorporate a single or multiple sensors registering the state of the apparatus and the treatment area. For example, a thermal sensor can be used to initiate the heating phase of the cycle when tissue temperature drops below a certain threshold, and initiate the cooling phase of the cycle when the temperature exceeds another threshold. Other sensor types include, but are not limited to, scanning speed sensors, contact sensors, pressure sensors, skin detectors, and skin response sensors.
- In some embodiments of the invention, an additional stimulating implement can be integrated into the applicator (see
FIG. 8 b). The purpose of the implement is to optimize tissue structure and facilitate thermal cycling. The implement can be, for example, mechanical (knitting, rolling, or pulling action) or vacuum (negative/positive pressure in the treatment area). Other forms of tissue stimulation may also be utilized, for example, ultrasonic or other acoustic stimulation, or electrical stimulation. - While several embodiments of the invention have been described and illustrated herein, those of ordinary skill in the art will readily envision a variety of other means and structures for performing the functions and/or obtaining the results and/or advantages described herein, and each of such variations or modifications is deemed to be within the scope of the present invention. More generally, those skilled in the art would readily appreciate that all parameters, dimensions, materials, and configurations described herein are meant to be exemplary and that actual parameters, dimensions, materials, and configurations will depend upon specific applications for which the teachings of the present invention are used. Those skilled in the art will recognize, or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments of the invention described herein. It is, therefore, to be understood that the foregoing embodiments are presented by way of example only and that, within the scope of the appended claims and equivalents thereto, the invention may be practiced otherwise than as specifically described. The present invention is directed to each individual feature, system, material and/or method described herein. In addition, any combination of two or more such features, systems, materials and/or methods, if such features, systems, materials and/or methods are not mutually inconsistent, is included within the scope of the present invention. In the claims, all transitional phrases or phrases of inclusion, such as “comprising,” “including,” “carrying,” “having,” “containing,” and the like are to be understood to be open-ended, i.e. to mean “including but not limited to.” Only the transitional phrases or phrases of inclusion “consisting of” and “consisting essentially of” are to be interpreted as closed or semi-closed phrases, respectively.
Claims (48)
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---|---|---|---|---|
US8182473B2 (en) | 1999-01-08 | 2012-05-22 | Palomar Medical Technologies | Cooling system for a photocosmetic device |
US6273884B1 (en) | 1997-05-15 | 2001-08-14 | Palomar Medical Technologies, Inc. | Method and apparatus for dermatology treatment |
US20060149343A1 (en) * | 1996-12-02 | 2006-07-06 | Palomar Medical Technologies, Inc. | Cooling system for a photocosmetic device |
US6104959A (en) | 1997-07-31 | 2000-08-15 | Microwave Medical Corp. | Method and apparatus for treating subcutaneous histological features |
US6050943A (en) | 1997-10-14 | 2000-04-18 | Guided Therapy Systems, Inc. | Imaging, therapy, and temperature monitoring ultrasonic system |
AU3450799A (en) | 1998-03-12 | 1999-09-27 | Palomar Medical Technologies, Inc. | System for electromagnetic radiation of the skin |
US7351252B2 (en) * | 2002-06-19 | 2008-04-01 | Palomar Medical Technologies, Inc. | Method and apparatus for photothermal treatment of tissue at depth |
EP1347711B1 (en) * | 2000-12-28 | 2006-11-15 | Palomar Medical Technologies, Inc. | Apparatus for therapeutic emr treatment of the skin |
US7914453B2 (en) | 2000-12-28 | 2011-03-29 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US6648904B2 (en) * | 2001-11-29 | 2003-11-18 | Palomar Medical Technologies, Inc. | Method and apparatus for controlling the temperature of a surface |
AU2002367397A1 (en) * | 2001-12-27 | 2003-07-24 | Palomar Medical Technologies, Inc. | Method and apparatus for improved vascular related treatment |
EP1917935B1 (en) * | 2002-03-15 | 2011-01-12 | The General Hospital Corporation | Method for selective disruption of fatty tissue by controlled cooling |
US8840608B2 (en) | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
EP1558339A1 (en) * | 2002-10-07 | 2005-08-03 | Palomar Medical Technologies, Inc. | Apparatus for performing photobiostimulation |
US20070219604A1 (en) * | 2006-03-20 | 2007-09-20 | Palomar Medical Technologies, Inc. | Treatment of tissue with radiant energy |
US20070213792A1 (en) * | 2002-10-07 | 2007-09-13 | Palomar Medical Technologies, Inc. | Treatment Of Tissue Volume With Radiant Energy |
EP2522294A2 (en) | 2002-10-23 | 2012-11-14 | Palomar Medical Technologies, Inc. | Phototreatment device for use with coolants and topical substances |
AU2003301111A1 (en) * | 2002-12-20 | 2004-07-22 | Palomar Medical Technologies, Inc. | Apparatus for light treatment of acne and other disorders of follicles |
WO2004075681A2 (en) * | 2003-02-25 | 2004-09-10 | Spectragenics, Inc. | Self-contained, eye-safe hair-regrowth-inhibition apparatus and method |
EP1596745B1 (en) * | 2003-02-25 | 2016-02-17 | Tria Beauty, Inc. | Self-contained, diode-laser-based dermatologic treatment apparatus |
ES2570989T3 (en) * | 2003-02-25 | 2016-05-23 | Tria Beauty Inc | Safe dermatological treatment device for the eye |
JP2006518614A (en) * | 2003-02-25 | 2006-08-17 | スペクトラジェニクス インコーポレイテッド | Acne treatment apparatus and method |
US7981111B2 (en) | 2003-02-25 | 2011-07-19 | Tria Beauty, Inc. | Method and apparatus for the treatment of benign pigmented lesions |
EP2604216B1 (en) * | 2003-02-25 | 2018-08-22 | Tria Beauty, Inc. | Self-contained, diode-laser-based dermatologic treatment apparatus |
US7413567B2 (en) * | 2003-02-25 | 2008-08-19 | Spectragenics, Inc. | Optical sensor and method for identifying the presence of skin |
JP4435149B2 (en) * | 2003-03-06 | 2010-03-17 | トリア ビューティ インコーポレイテッド | Skin contact sensing device |
WO2005065565A1 (en) * | 2003-12-31 | 2005-07-21 | Palomar Medical Technologies, Inc. | Dermatological treatment with vusualization |
US8777935B2 (en) | 2004-02-25 | 2014-07-15 | Tria Beauty, Inc. | Optical sensor and method for identifying the presence of skin |
AU2005231443B2 (en) | 2004-04-01 | 2012-02-23 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
EP1748740A4 (en) * | 2004-04-09 | 2008-12-31 | Palomar Medical Tech Inc | Methods and products for producing lattices of emr-treated islets in tissues, and uses therefor |
US20080132886A1 (en) * | 2004-04-09 | 2008-06-05 | Palomar Medical Technologies, Inc. | Use of fractional emr technology on incisions and internal tissues |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
US7393325B2 (en) | 2004-09-16 | 2008-07-01 | Guided Therapy Systems, L.L.C. | Method and system for ultrasound treatment with a multi-directional transducer |
US7824348B2 (en) | 2004-09-16 | 2010-11-02 | Guided Therapy Systems, L.L.C. | System and method for variable depth ultrasound treatment |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US20120165668A1 (en) | 2010-08-02 | 2012-06-28 | Guided Therapy Systems, Llc | Systems and methods for treating acute and/or chronic injuries in soft tissue |
KR101328103B1 (en) | 2004-10-06 | 2013-11-13 | 가이디드 테라피 시스템스, 엘.엘.씨. | Method and system for noninvasive cosmetic enhancement |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
KR20130080477A (en) * | 2004-10-06 | 2013-07-12 | 가이디드 테라피 시스템스, 엘.엘.씨. | System of ultrasound treatment |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US20060111744A1 (en) | 2004-10-13 | 2006-05-25 | Guided Therapy Systems, L.L.C. | Method and system for treatment of sweat glands |
US8663112B2 (en) | 2004-10-06 | 2014-03-04 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
US7758524B2 (en) | 2004-10-06 | 2010-07-20 | Guided Therapy Systems, L.L.C. | Method and system for ultra-high frequency ultrasound treatment |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US7780656B2 (en) * | 2004-12-10 | 2010-08-24 | Reliant Technologies, Inc. | Patterned thermal treatment using patterned cryogen spray and irradiation by light |
US8277495B2 (en) * | 2005-01-13 | 2012-10-02 | Candela Corporation | Method and apparatus for treating a diseased nail |
US8244369B2 (en) * | 2005-01-28 | 2012-08-14 | Syneron Medical Ltd. | Device and method for treating skin with temperature control |
CN101115438B (en) * | 2005-02-07 | 2010-06-16 | 皇家飞利浦电子股份有限公司 | Device for determining a stress level of a person and providing feedback on the basis of the stress level as determined |
JP4695188B2 (en) | 2005-04-25 | 2011-06-08 | アーデント サウンド, インコーポレイテッド | Method and apparatus for improving the safety of computer peripherals |
US7217265B2 (en) * | 2005-05-18 | 2007-05-15 | Cooltouch Incorporated | Treatment of cellulite with mid-infrared radiation |
US7713266B2 (en) * | 2005-05-20 | 2010-05-11 | Myoscience, Inc. | Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat) |
US20070176262A1 (en) * | 2005-08-11 | 2007-08-02 | Ernest Sirkin | Series connection of a diode laser bar |
US20070173799A1 (en) * | 2005-09-01 | 2007-07-26 | Hsia James C | Treatment of fatty tissue adjacent an eye |
US9028469B2 (en) * | 2005-09-28 | 2015-05-12 | Candela Corporation | Method of treating cellulite |
US20070078502A1 (en) * | 2005-10-05 | 2007-04-05 | Thermage, Inc. | Method and apparatus for estimating a local impedance factor |
US20070083190A1 (en) * | 2005-10-11 | 2007-04-12 | Yacov Domankevitz | Compression device for a laser handpiece |
US7957815B2 (en) * | 2005-10-11 | 2011-06-07 | Thermage, Inc. | Electrode assembly and handpiece with adjustable system impedance, and methods of operating an energy-based medical system to treat tissue |
JPWO2007046346A1 (en) * | 2005-10-18 | 2009-04-23 | テルモ株式会社 | Light irradiation device |
US8702691B2 (en) * | 2005-10-19 | 2014-04-22 | Thermage, Inc. | Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue |
US7891362B2 (en) * | 2005-12-23 | 2011-02-22 | Candela Corporation | Methods for treating pigmentary and vascular abnormalities in a dermal region |
WO2007093941A1 (en) * | 2006-02-17 | 2007-08-23 | Koninklijke Philips Electronics N.V. | Orthosis and treatment method |
US7854754B2 (en) | 2006-02-22 | 2010-12-21 | Zeltiq Aesthetics, Inc. | Cooling device for removing heat from subcutaneous lipid-rich cells |
EP1837050A1 (en) * | 2006-03-24 | 2007-09-26 | WaveLight AG | Device for the irradiation of the skin |
US20070239144A1 (en) * | 2006-04-06 | 2007-10-11 | Lite Touch Ltd. | Methods of photothermolysis |
JP4703724B2 (en) * | 2006-04-28 | 2011-06-15 | ゼルティック エステティックス インコーポレイテッド | Antifreeze for use in therapeutic devices with improved cooling of subcutaneous lipid-rich cells |
US20070282318A1 (en) * | 2006-05-16 | 2007-12-06 | Spooner Gregory J | Subcutaneous thermolipolysis using radiofrequency energy |
US20070270925A1 (en) * | 2006-05-17 | 2007-11-22 | Juniper Medical, Inc. | Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature |
US20070268955A1 (en) * | 2006-05-17 | 2007-11-22 | Pohl Hermann K | Thermal fluid device with remote temperature indicator |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
US9132031B2 (en) * | 2006-09-26 | 2015-09-15 | Zeltiq Aesthetics, Inc. | Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile |
US8192474B2 (en) * | 2006-09-26 | 2012-06-05 | Zeltiq Aesthetics, Inc. | Tissue treatment methods |
US20080077201A1 (en) * | 2006-09-26 | 2008-03-27 | Juniper Medical, Inc. | Cooling devices with flexible sensors |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US8641660B2 (en) * | 2006-10-04 | 2014-02-04 | P Tech, Llc | Methods and devices for controlling biologic microenvironments |
US9101524B2 (en) * | 2006-11-09 | 2015-08-11 | Lumenis Ltd. | Apparatus and method for treating tissue |
WO2008074005A1 (en) * | 2006-12-13 | 2008-06-19 | Palomar Medical Technologies, Inc. | Cosmetic and biomedical applications of ultrasonic energy and methods of generation thereof |
WO2008091983A2 (en) * | 2007-01-25 | 2008-07-31 | Thermage, Inc. | Treatment apparatus and methods for inducing microburn patterns in tissue |
US20080188914A1 (en) * | 2007-02-01 | 2008-08-07 | Candela Corporation | Detachable handpiece |
US20080221649A1 (en) * | 2007-03-09 | 2008-09-11 | Agustina Echague | Method of sequentially treating tissue |
CN101711134B (en) | 2007-04-19 | 2016-08-17 | 米勒玛尔实验室公司 | Tissue is applied the system of microwave energy and in organized layer, produces the system of tissue effect |
US9241763B2 (en) | 2007-04-19 | 2016-01-26 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
EP3391844A1 (en) | 2007-04-19 | 2018-10-24 | Miramar Labs, Inc. | Apparatus for reducing sweat production |
US8688228B2 (en) | 2007-04-19 | 2014-04-01 | Miramar Labs, Inc. | Systems, apparatus, methods and procedures for the noninvasive treatment of tissue using microwave energy |
WO2008131306A1 (en) | 2007-04-19 | 2008-10-30 | The Foundry, Inc. | Systems and methods for creating an effect using microwave energy to specified tissue |
EP2767308B1 (en) | 2007-04-19 | 2016-04-13 | Miramar Labs, Inc. | Devices, and systems for non-invasive delivery of microwave therapy |
TWI526233B (en) | 2007-05-07 | 2016-03-21 | 指導治療系統股份有限公司 | Methods and systems for modulating medicants using acoustic energy |
ES2699477T3 (en) | 2007-05-07 | 2019-02-11 | Guided Therapy Systems Llc | Methods and systems for coupling and focusing acoustic energy using a coupling member |
US20150174388A1 (en) | 2007-05-07 | 2015-06-25 | Guided Therapy Systems, Llc | Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue |
AU2012244313B2 (en) * | 2007-05-18 | 2014-11-27 | Zeltiq Aesthetics, Inc. | Device for enhanced removal of heat from subcutaneous lipid-rich cells having an actuator |
US20080287839A1 (en) * | 2007-05-18 | 2008-11-20 | Juniper Medical, Inc. | Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator |
WO2008154000A1 (en) * | 2007-06-08 | 2008-12-18 | Cynosure, Inc. | Thermal surgery safety suite |
US20090018522A1 (en) * | 2007-07-10 | 2009-01-15 | Anima Ventures Ltd. | Tissue modification by targeted delivery of heat |
WO2009009661A1 (en) * | 2007-07-10 | 2009-01-15 | Thermage, Inc. | Treatment apparatus and methods for delivering high frequency energy across large tissue areas |
US20090018625A1 (en) * | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Managing system temperature to remove heat from lipid-rich regions |
US8523927B2 (en) | 2007-07-13 | 2013-09-03 | Zeltiq Aesthetics, Inc. | System for treating lipid-rich regions |
US20090018626A1 (en) * | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | User interfaces for a system that removes heat from lipid-rich regions |
US20090018624A1 (en) * | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Limiting use of disposable system patient protection devices |
EP2194899A4 (en) * | 2007-08-08 | 2012-11-28 | Tria Beauty Inc | Capacitive sensing method and device for detecting skin |
US8285390B2 (en) * | 2007-08-21 | 2012-10-09 | Zeltiq Aesthetics, Inc. | Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue |
US20090149796A1 (en) * | 2007-12-06 | 2009-06-11 | Jones Dennis R | Use of Iontophoresis and Ultrasound to Deliver Melanin or Other Chromophores for Laser Hair Removal |
ES2471971T3 (en) | 2007-12-12 | 2014-06-27 | Miramar Labs, Inc. | System and apparatus for non-invasive treatment of tissue using microwave energy |
US20090254005A1 (en) * | 2008-04-03 | 2009-10-08 | Eilaz Babaev | Ultrasound assisted tissue welding device |
ITMI20080628A1 (en) * | 2008-04-09 | 2009-10-10 | Novavision Group S R L | ULTRASONIC DEVICE PERFECTED, PARTICULARLY FOR THE TREATMENT OF ADIPOSE FABRIC. |
EP2268198A4 (en) * | 2008-04-25 | 2014-10-15 | Tria Beauty Inc | Optical sensor and method for identifying the presence of skin and the pigmentation of skin |
CA3206234A1 (en) | 2008-06-06 | 2009-12-10 | Ulthera, Inc. | A system and method for cosmetic treatment and imaging |
WO2010003106A2 (en) * | 2008-07-02 | 2010-01-07 | Niveus Medical Inc. | Systems and methods for automated muscle stimulation |
US8892210B2 (en) | 2008-07-02 | 2014-11-18 | Niveus Medical, Inc. | Devices, systems, and methods for automated optimization of energy delivery |
US20100036368A1 (en) * | 2008-08-11 | 2010-02-11 | Laura England | Method of selectively heating adipose tissue |
US9149386B2 (en) | 2008-08-19 | 2015-10-06 | Niveus Medical, Inc. | Devices and systems for stimulation of tissues |
WO2010027874A2 (en) * | 2008-08-26 | 2010-03-11 | Niveus Medical, Inc. | Device, system, and method to improve powered muscle stimulation performance in the presence of tissue edema |
EP2346428B1 (en) * | 2008-09-25 | 2019-11-06 | Zeltiq Aesthetics, Inc. | Treatment planning systems and methods for body contouring applications |
US9532717B2 (en) * | 2008-10-28 | 2017-01-03 | The Procter & Gamble Company | Method for diagnosing vulvovaginal disorders |
US8603073B2 (en) * | 2008-12-17 | 2013-12-10 | Zeltiq Aesthetics, Inc. | Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells |
CA2751527C (en) * | 2009-02-20 | 2020-05-05 | Niveus Medical, Inc. | Systems and methods of powered muscle stimulation using an energy guidance field |
US20100234737A1 (en) * | 2009-03-12 | 2010-09-16 | Miranda Aref Farage | Method for assessing skin irritation using infrared light |
EP2421609B1 (en) * | 2009-04-22 | 2013-02-13 | Radiancy Inc. | Skin treatment device utilizing light and temperature |
ES2916830T3 (en) | 2009-04-30 | 2022-07-06 | Zeltiq Aesthetics Inc | Device for removing heat from lipid-rich subcutaneous cells |
AU2010319602B2 (en) * | 2009-11-11 | 2015-09-24 | Sage Products, Llc | Synergistic muscle activation device |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US20110190745A1 (en) * | 2009-12-04 | 2011-08-04 | Uebelhoer Nathan S | Treatment of sweat glands |
US9314368B2 (en) * | 2010-01-25 | 2016-04-19 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associates devices, systems and methods |
US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
EP2595704A1 (en) * | 2010-07-24 | 2013-05-29 | LipoSonix, Inc. | Apparatus and methods for non-invasive body contouring |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9636522B2 (en) * | 2010-08-11 | 2017-05-02 | Koninklijke Philips N.V. | Phototherapy method and device |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US10722395B2 (en) | 2011-01-25 | 2020-07-28 | Zeltiq Aesthetics, Inc. | Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells |
JPWO2012144504A1 (en) * | 2011-04-19 | 2014-07-28 | 博基 島 | Cell activation device |
WO2013009784A2 (en) | 2011-07-10 | 2013-01-17 | Guided Therapy Systems, Llc | Systems and method for accelerating healing of implanted material and/or native tissue |
WO2013012641A1 (en) | 2011-07-11 | 2013-01-24 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9314301B2 (en) | 2011-08-01 | 2016-04-19 | Miramar Labs, Inc. | Applicator and tissue interface module for dermatological device |
US9700245B2 (en) | 2011-09-23 | 2017-07-11 | Itrace Biomedical Inc. | Transdermal analyte extraction and detection system and the method thereof |
US20130123765A1 (en) * | 2011-11-16 | 2013-05-16 | Btl Holdings Limited | Methods and systems for subcutaneous treatments |
US8548599B2 (en) * | 2011-11-16 | 2013-10-01 | Btl Holdings Limited | Methods and systems for subcutaneous treatments |
US9867996B2 (en) | 2011-11-16 | 2018-01-16 | Btl Holdings Limited | Methods and systems for skin treatment |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
BR112014027514A2 (en) * | 2012-05-07 | 2017-06-27 | Koninklijke Philips Nv | method of treating a raised aspect of skin tissue in mammalian skin tissue; system for treating radiofrequency energy skin tissue; and roll for a system |
US9522289B2 (en) | 2012-05-08 | 2016-12-20 | The Regents Of The University Of California | Selective fat removal using photothermal heating |
WO2014004526A1 (en) * | 2012-06-25 | 2014-01-03 | Niveus Medical, Inc. | Devices and systems for stimulation of tissues |
CN110251839A (en) | 2012-09-10 | 2019-09-20 | 真皮光子公司 | The medical device of dermatology |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US10179239B2 (en) | 2013-01-15 | 2019-01-15 | Itrace Biomedical Inc. | Personalized pain management treatments |
US9710607B2 (en) * | 2013-01-15 | 2017-07-18 | Itrace Biomedical Inc. | Portable electronic therapy device and the method thereof |
RU2514107C1 (en) * | 2013-03-06 | 2014-04-27 | Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") | Method for photodynamic therapy of patients with metastatic tumoural pleuritis |
CN204017181U (en) | 2013-03-08 | 2014-12-17 | 奥赛拉公司 | Aesthstic imaging and processing system, multifocal processing system and perform the system of aesthetic procedure |
US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
WO2014153149A1 (en) | 2013-03-14 | 2014-09-25 | Ellman International, Inc. | Electrosurgical systems and methods |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
WO2014146022A2 (en) | 2013-03-15 | 2014-09-18 | Guided Therapy Systems Llc | Ultrasound treatment device and methods of use |
WO2014145148A2 (en) | 2013-03-15 | 2014-09-18 | Ellman International, Inc. | Surgical instruments and systems with multimodes of treatments and electrosurgical operation |
US10779885B2 (en) | 2013-07-24 | 2020-09-22 | Miradry. Inc. | Apparatus and methods for the treatment of tissue using microwave energy |
KR102364395B1 (en) * | 2013-08-09 | 2022-02-17 | 더 제너럴 하스피탈 코포레이션 | Method and apparatus for treating dermal melasma |
USD747800S1 (en) | 2013-09-10 | 2016-01-19 | Dermal Photonics Corporation | Dermatological medical device |
US10064940B2 (en) | 2013-12-11 | 2018-09-04 | Siva Therapeutics Inc. | Multifunctional radiation delivery apparatus and method |
US10575890B2 (en) | 2014-01-31 | 2020-03-03 | Zeltiq Aesthetics, Inc. | Treatment systems and methods for affecting glands and other targeted structures |
WO2015117005A1 (en) * | 2014-01-31 | 2015-08-06 | The General Hospital Corporation | Cooling device to disrupt function sebaceous glands |
US10675176B1 (en) | 2014-03-19 | 2020-06-09 | Zeltiq Aesthetics, Inc. | Treatment systems, devices, and methods for cooling targeted tissue |
USD777338S1 (en) | 2014-03-20 | 2017-01-24 | Zeltiq Aesthetics, Inc. | Cryotherapy applicator for cooling tissue |
WO2015160708A1 (en) | 2014-04-18 | 2015-10-22 | Ulthera, Inc. | Band transducer ultrasound therapy |
US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
US9820801B2 (en) * | 2014-06-03 | 2017-11-21 | Suzanne Anderer | Epilation by thermolysis |
US10935174B2 (en) | 2014-08-19 | 2021-03-02 | Zeltiq Aesthetics, Inc. | Stress relief couplings for cryotherapy apparatuses |
US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US20170281965A1 (en) * | 2014-09-04 | 2017-10-05 | Tom Kerber | Assembly for photodynamic therapy |
WO2016044058A1 (en) | 2014-09-15 | 2016-03-24 | Sung Oh | Cooling system for localized and non-invasive cooling treatment |
CA2974517A1 (en) * | 2015-01-23 | 2016-07-28 | Marcio Marc Abreu | Apparatus and method for skin treatment |
WO2016126806A1 (en) * | 2015-02-03 | 2016-08-11 | Ino Beauty Inc. | Anti-aging device for stimulating scalp and hair health |
US10039600B2 (en) * | 2015-02-03 | 2018-08-07 | L'oreal | Apparatus and method for skin treatment using pulsed light |
US9962553B2 (en) | 2015-03-04 | 2018-05-08 | Btl Holdings Limited | Device and method for contactless skin treatment |
US10737109B2 (en) | 2015-04-23 | 2020-08-11 | Cynosure, Llc | Systems and methods of unattended treatment of a subject's head or neck |
US10518104B2 (en) | 2015-04-23 | 2019-12-31 | Cynosure, Llc | Systems and methods of unattended treatment |
US10737112B2 (en) * | 2015-05-13 | 2020-08-11 | Sauna Works Inc. | Water-filtered near infrared sauna |
WO2016209834A1 (en) | 2015-06-22 | 2016-12-29 | Quantum Dynamics L.L.C. | Device for providing body temperature regulation and/or therapeutic light directed to vasculature |
US10569094B2 (en) | 2015-07-01 | 2020-02-25 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US10569095B1 (en) | 2015-07-01 | 2020-02-25 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US9937358B2 (en) | 2015-07-01 | 2018-04-10 | Btl Holdings Limited | Aesthetic methods of biological structure treatment by magnetic field |
US10478634B2 (en) | 2015-07-01 | 2019-11-19 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
CN108136199B (en) | 2015-07-28 | 2022-03-01 | 诺欧生物有限责任公司 | Phototherapy device for dermatological treatment of the scalp |
CN108136196B (en) | 2015-07-28 | 2020-07-17 | 诺欧生物有限责任公司 | System and method for phototherapy modulation of nitric oxide |
US10080906B2 (en) * | 2015-09-30 | 2018-09-25 | Btl Holdings Limited | Methods and devices for tissue treatment using mechanical stimulation and electromagnetic field |
US11484724B2 (en) * | 2015-09-30 | 2022-11-01 | Btl Medical Solutions A.S. | Methods and devices for tissue treatment using mechanical stimulation and electromagnetic field |
US9636516B2 (en) * | 2015-09-30 | 2017-05-02 | Btl Holdings Limited | Methods and devices for tissue treatment using shock waves and electromagnetic field |
WO2017070112A1 (en) * | 2015-10-19 | 2017-04-27 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
FR3046545B1 (en) * | 2016-01-07 | 2021-05-28 | Urgo Rech Innovation Et Developpement | DERMATOLOGICAL TREATMENT DEVICE EQUIPPED WITH A FAN MONITORING MEANS |
CA3009414A1 (en) | 2016-01-07 | 2017-07-13 | Zeltiq Aesthetics, Inc. | Temperature-dependent adhesion between applicator and skin during cooling of tissue |
PL3405294T3 (en) | 2016-01-18 | 2023-05-08 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board |
US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
EP3207957A1 (en) * | 2016-02-22 | 2017-08-23 | Koninklijke Philips N.V. | Hair care device |
US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
IL293809B2 (en) | 2016-08-16 | 2023-09-01 | Ulthera Inc | Systems and methods for cosmetic ultrasound treatment of skin |
KR20230154105A (en) | 2016-11-22 | 2023-11-07 | 도미니언 에스테틱 테크놀로지스, 인크. | Systems and methods for aesthetic treatment |
US10293148B2 (en) * | 2017-01-06 | 2019-05-21 | Paul Dabney | System, retainer and method of preventing and treating nosocomial infections including methicillin-resistant Staphylococcus aureus infections |
US10744337B2 (en) * | 2017-04-13 | 2020-08-18 | Multi Radiance Medical | Photobiomodulation therapy to reduce the effects of fibromyalgia |
US11076879B2 (en) | 2017-04-26 | 2021-08-03 | Zeltiq Aesthetics, Inc. | Shallow surface cryotherapy applicators and related technology |
US20190099616A1 (en) * | 2017-10-03 | 2019-04-04 | General Electric Company | Omniblanket for infant warming and increased efficiency phototherapy |
US11400308B2 (en) | 2017-11-21 | 2022-08-02 | Cutera, Inc. | Dermatological picosecond laser treatment systems and methods using optical parametric oscillator |
US11819259B2 (en) | 2018-02-07 | 2023-11-21 | Cynosure, Inc. | Methods and apparatus for controlled RF treatments and RF generator system |
WO2019164836A1 (en) | 2018-02-20 | 2019-08-29 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
WO2020028472A1 (en) | 2018-07-31 | 2020-02-06 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
US10677866B1 (en) * | 2018-11-28 | 2020-06-09 | Insightec, Ltd. | Systems and methods for correcting measurement artifacts in MR thermometry |
USD1005484S1 (en) | 2019-07-19 | 2023-11-21 | Cynosure, Llc | Handheld medical instrument and docking base |
US10864380B1 (en) | 2020-02-29 | 2020-12-15 | Cutera, Inc. | Systems and methods for controlling therapeutic laser pulse duration |
US11253720B2 (en) | 2020-02-29 | 2022-02-22 | Cutera, Inc. | Dermatological systems and methods with handpiece for coaxial pulse delivery and temperature sensing |
US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
GB202005820D0 (en) * | 2020-04-21 | 2020-06-03 | Michelson Diagnostics Ltd | Treatment apparatus |
CA3177950A1 (en) * | 2020-05-05 | 2021-11-11 | Lumeda Inc. | Time mulitplexed dosimetry system and method |
US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
Citations (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2068721A (en) * | 1932-11-18 | 1937-01-26 | Wappler Frederick Charles | Method for electrosurgical severance of adhesions |
US2669771A (en) * | 1949-11-17 | 1954-02-23 | Gen Motors Corp | Armature coil lead staker |
US3794028A (en) * | 1973-02-27 | 1974-02-26 | A Griffin | Method for injecting chemicals into the papilla for depilation |
US3793723A (en) * | 1971-12-03 | 1974-02-26 | Ultrasonic Systems | Ultrasonic replaceable shaving head and razor |
US3858577A (en) * | 1974-04-05 | 1975-01-07 | Univ Southern California | Fiber optic laser light delivery system |
US3939560A (en) * | 1973-01-31 | 1976-02-24 | Wilkinson Sword Ltd. | Shaving equipment |
US4133503A (en) * | 1975-08-29 | 1979-01-09 | Bliss John H | Entry, display and use of data employed to overcome aircraft control problems due to wind shear |
US4139342A (en) * | 1977-07-18 | 1979-02-13 | Hughes Aircraft Company | Dye impregnated plastics for laser applications |
US4188927A (en) * | 1978-01-12 | 1980-02-19 | Valleylab, Inc. | Multiple source electrosurgical generator |
US4313431A (en) * | 1978-12-06 | 1982-02-02 | Messerschmitt-Boelkow-Blohm Gesellschaft Mit Beschraenkter Haftung | Endoscopic apparatus with a laser light conductor |
US4428368A (en) * | 1980-09-29 | 1984-01-31 | Masakatsu Torii | Massage device |
US4492601A (en) * | 1982-10-15 | 1985-01-08 | Daiichi Seito Kabushiki Kaisha | Process for clarifying and desalinating sugar cane syrup or molasses |
US4566271A (en) * | 1982-12-01 | 1986-01-28 | Lucas Industries Public Limited Company | Engine systems |
US4638800A (en) * | 1985-02-08 | 1987-01-27 | Research Physics, Inc | Laser beam surgical system |
US4718416A (en) * | 1984-01-13 | 1988-01-12 | Kabushiki Kaisha Toshiba | Laser treatment apparatus |
US4741338A (en) * | 1986-10-06 | 1988-05-03 | Toshiaki Miyamae | Thermoelectric physical remedy apparatus |
US4799479A (en) * | 1984-10-24 | 1989-01-24 | The Beth Israel Hospital Association | Method and apparatus for angioplasty |
US4891817A (en) * | 1988-06-13 | 1990-01-02 | Eastman Kodak Company | Pulsed dye laser apparatus for high PRF operation |
US4890989A (en) * | 1987-02-12 | 1990-01-02 | Bernard Zimmern | Positive displacement machine with a plastic gate pinton |
US4896329A (en) * | 1989-06-01 | 1990-01-23 | Exciton Incorporated | Laser dye liquids, laser dye instruments and methods |
US5080660A (en) * | 1990-05-11 | 1992-01-14 | Applied Urology, Inc. | Electrosurgical electrode |
US5178617A (en) * | 1991-07-09 | 1993-01-12 | Laserscope | System for controlled distribution of laser dosage |
US5180378A (en) * | 1989-04-24 | 1993-01-19 | Abiomed, Inc. | Laser surgery system |
US5182557A (en) * | 1989-09-20 | 1993-01-26 | Semborg Recrob, Corp. | Motorized joystick |
US5281216A (en) * | 1992-03-31 | 1994-01-25 | Valleylab, Inc. | Electrosurgical bipolar treating apparatus |
US5281211A (en) * | 1989-06-07 | 1994-01-25 | University Of Miami, School Of Medicine, Dept. Of Ophthalmology | Noncontact laser microsurgical apparatus |
US5380317A (en) * | 1988-06-10 | 1995-01-10 | Trimedyne Laser Systems, Inc. | Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium |
US5383876A (en) * | 1992-11-13 | 1995-01-24 | American Cardiac Ablation Co., Inc. | Fluid cooled electrosurgical probe for cutting and cauterizing tissue |
US5386427A (en) * | 1994-02-10 | 1995-01-31 | Massachusetts Institute Of Technology | Thermally controlled lenses for lasers |
US5484436A (en) * | 1991-06-07 | 1996-01-16 | Hemostatic Surgery Corporation | Bi-polar electrosurgical instruments and methods of making |
US5486170A (en) * | 1992-10-26 | 1996-01-23 | Ultrasonic Sensing And Monitoring Systems | Medical catheter using optical fibers that transmit both laser energy and ultrasonic imaging signals |
US5486172A (en) * | 1989-05-30 | 1996-01-23 | Chess; Cyrus | Apparatus for treating cutaneous vascular lesions |
US5488626A (en) * | 1991-01-14 | 1996-01-30 | Light Age, Inc. | Method of and apparatus for pumping of transition metal ion containing solid state lasers using diode laser sources |
US5595568A (en) * | 1995-02-01 | 1997-01-21 | The General Hospital Corporation | Permanent hair removal using optical pulses |
US5598426A (en) * | 1995-02-03 | 1997-01-28 | Candela Laser Corporation | Method and dye laser apparatus for producing long pulses of laser radiation |
US5707403A (en) * | 1993-02-24 | 1998-01-13 | Star Medical Technologies, Inc. | Method for the laser treatment of subsurface blood vessels |
US5707401A (en) * | 1994-03-10 | 1998-01-13 | Esc Medical Systems, Ltd. | Apparatus for an efficient photodynamic treatment |
US5707369A (en) * | 1995-04-24 | 1998-01-13 | Ethicon Endo-Surgery, Inc. | Temperature feedback monitor for hemostatic surgical instrument |
US5830208A (en) * | 1997-01-31 | 1998-11-03 | Laserlite, Llc | Peltier cooled apparatus and methods for dermatological treatment |
US5860967A (en) * | 1993-07-21 | 1999-01-19 | Lucid, Inc. | Dermatological laser treatment system with electronic visualization of the area being treated |
US6015404A (en) * | 1996-12-02 | 2000-01-18 | Palomar Medical Technologies, Inc. | Laser dermatology with feedback control |
US6104959A (en) * | 1997-07-31 | 2000-08-15 | Microwave Medical Corp. | Method and apparatus for treating subcutaneous histological features |
US6171300B1 (en) * | 1997-09-04 | 2001-01-09 | Linvatec Corporation | Tubing cassette and method for cooling a surgical handpiece |
US6171332B1 (en) * | 1992-10-23 | 2001-01-09 | Photo Therapeutics Limited | Light source |
US6171301B1 (en) * | 1994-04-05 | 2001-01-09 | The Regents Of The University Of California | Apparatus and method for dynamic cooling of biological tissues for thermal mediated surgery |
US6171302B1 (en) * | 1997-03-19 | 2001-01-09 | Gerard Talpalriu | Apparatus and method including a handpiece for synchronizing the pulsing of a light source |
US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
US6174325B1 (en) * | 1992-10-20 | 2001-01-16 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US6176854B1 (en) * | 1997-10-08 | 2001-01-23 | Robert Roy Cone | Percutaneous laser treatment |
US20020002367A1 (en) * | 2000-06-30 | 2002-01-03 | Nikolai Tankovich | Twin light laser |
US20020004066A1 (en) * | 2000-02-29 | 2002-01-10 | Theodore Stanley | Transdermal drug patch with attached pocket for controlled heating device |
US6338855B1 (en) * | 1996-10-25 | 2002-01-15 | The Procter & Gamble Company | Cleansing articles for skin and/or hair which also deposit skin care actives |
US20020005475A1 (en) * | 2000-04-28 | 2002-01-17 | Zenzie Henry H. | Contact detecting method and apparatus for an optical radiation handpiece |
US6340495B1 (en) * | 1997-12-16 | 2002-01-22 | Galderma Research & Development | Device including a chromophoric composition to be applied to the skin, a method of fabricating such a device, and uses therefor |
US20020013572A1 (en) * | 2000-05-19 | 2002-01-31 | Berlin Michael S. | Delivery system and method of use for the eye |
US6350276B1 (en) * | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US20030004499A1 (en) * | 2000-01-13 | 2003-01-02 | Mcdaniel David H. | Method and apparatus for the photomodulation of living cells |
US6503486B2 (en) * | 2001-03-12 | 2003-01-07 | Colgate Palmolive Company | Strip for whitening tooth surfaces |
US6503269B2 (en) * | 2000-06-12 | 2003-01-07 | Scott A. Nield | Method of treating intervertebral discs using optical energy and optical temperature feedback |
US20030009205A1 (en) * | 1997-08-25 | 2003-01-09 | Biel Merrill A. | Treatment device for topical photodynamic therapy and method of using same |
US20030009158A1 (en) * | 2001-07-09 | 2003-01-09 | Perricone Nicholas V. | Skin treatments using blue and violet light |
US6508813B1 (en) * | 1996-12-02 | 2003-01-21 | Palomar Medical Technologies, Inc. | System for electromagnetic radiation dermatology and head for use therewith |
US20030018373A1 (en) * | 2001-06-15 | 2003-01-23 | Uv-Solutions, Llc | Method and apparatus for sterilizing or disinfecting a region on a patient |
US6511475B1 (en) * | 1997-05-15 | 2003-01-28 | The General Hospital Corporation | Heads for dermatology treatment |
US20030023283A1 (en) * | 1998-11-30 | 2003-01-30 | Mcdaniel David H. | Method and apparatus for the stimulation of hair growth |
US20030023235A1 (en) * | 2001-07-27 | 2003-01-30 | Cense Abraham Josephus | Skin treating device comprising a processor for determination of the radiation pulse dose |
US20030023284A1 (en) * | 2001-02-20 | 2003-01-30 | Vladimir Gartstein | Method and apparatus for the in-vivo treatment of pathogens |
US6605080B1 (en) * | 1998-03-27 | 2003-08-12 | The General Hospital Corporation | Method and apparatus for the selective targeting of lipid-rich tissues |
US20040006332A1 (en) * | 2003-07-08 | 2004-01-08 | Michael Black | Hygienic treatments of body structures |
US6675425B1 (en) * | 1996-03-21 | 2004-01-13 | Keiji Iimura | Photocatalytic apparatus and method for activating photocatalytic material |
US6676654B1 (en) * | 1997-08-29 | 2004-01-13 | Asah Medico A/S | Apparatus for tissue treatment and having a monitor for display of tissue features |
US20040010298A1 (en) * | 2001-12-27 | 2004-01-15 | Gregory Altshuler | Method and apparatus for improved vascular related treatment |
US6679837B2 (en) * | 2001-06-01 | 2004-01-20 | Intlas Ltd. | Laser light irradiation apparatus |
US20040015156A1 (en) * | 1998-12-03 | 2004-01-22 | Vasily David B. | Method and apparatus for laser removal of hair |
US20040015158A1 (en) * | 2002-07-19 | 2004-01-22 | To-Mu Chen | Transilluminator device |
US6682524B1 (en) * | 1998-11-12 | 2004-01-27 | Asclepion Laser Technologies Gmbh | Dermatological hand piece |
US6682523B2 (en) * | 2001-02-21 | 2004-01-27 | John H. Shadduck | Devices and techniques for treating trabecular meshwork |
US20040019120A1 (en) * | 2002-03-12 | 2004-01-29 | Gracie Vargas | Laser treatment of cutaneous vascular lesions |
WO2004033040A1 (en) * | 2002-10-07 | 2004-04-22 | Palomar Medical Technologies, Inc. | Apparatus for performing photobiostimulation |
US20050015077A1 (en) * | 2003-07-14 | 2005-01-20 | Yevgeniy Kuklin | Method and apparatus for skin treatment using near infrared laser radiation |
US20060004306A1 (en) * | 2004-04-09 | 2006-01-05 | Palomar Medical Technologies, Inc. | Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor |
US20060009750A1 (en) * | 2001-03-02 | 2006-01-12 | Palomar Medical Technologies, Inc. | Apparatus and method for treatment using a patterned mask |
US20060007965A1 (en) * | 2004-07-12 | 2006-01-12 | Nikolai Tankovich | Passive Q-switch modulated fiber laser |
US6986903B2 (en) * | 2001-07-13 | 2006-01-17 | Mibelle Ag Cosmetics | Methods for treatment of human skin damaged by laser treatment or chemical peelings and compositions useful in such methods |
US20060013533A1 (en) * | 2001-12-10 | 2006-01-19 | Inolase 2002 Ltd. | Method and apparatus for improving safety during exposure to a monochromatic light source |
US6989007B2 (en) * | 2001-02-21 | 2006-01-24 | Solx, Inc. | Devices and techniques for treating glaucoma |
US6991644B2 (en) * | 2002-12-12 | 2006-01-31 | Cutera, Inc. | Method and system for controlled spatially-selective epidermal pigmentation phototherapy with UVA LEDs |
US6997923B2 (en) * | 2000-12-28 | 2006-02-14 | Palomar Medical Technologies, Inc. | Method and apparatus for EMR treatment |
US7097656B1 (en) * | 1999-03-18 | 2006-08-29 | Ls Private Joint-Stock Company | Device for the therapeutic and cosmetic photo-processing of biological tissue and method for using the same |
US7160289B2 (en) * | 2003-03-28 | 2007-01-09 | Vandolay, Inc. | Vascular occlusion systems and methods |
US7170034B2 (en) * | 2002-02-05 | 2007-01-30 | Radiancy Inc. | Pulsed electric shaver |
US20080003536A1 (en) * | 2002-04-09 | 2008-01-03 | Altshuler Gregory B | Method and apparatus for processing hard material |
US20080004608A1 (en) * | 2006-06-30 | 2008-01-03 | Alcon, Inc. | Multifunction surgical probe |
US20080004611A1 (en) * | 2004-10-05 | 2008-01-03 | Koninklijke Philips Electronics N.V. | Skin Treatment Device with Radiation Emission Protection |
US7322972B2 (en) * | 2002-04-10 | 2008-01-29 | The Regents Of The University Of California | In vivo port wine stain, burn and melanin depth determination using a photoacoustic probe |
US7351252B2 (en) * | 2002-06-19 | 2008-04-01 | Palomar Medical Technologies, Inc. | Method and apparatus for photothermal treatment of tissue at depth |
US7367341B2 (en) * | 2002-03-15 | 2008-05-06 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
US20090018624A1 (en) * | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Limiting use of disposable system patient protection devices |
US20090018531A1 (en) * | 2007-06-08 | 2009-01-15 | Cynosure, Inc. | Coaxial suction system for laser lipolysis |
US20090024193A1 (en) * | 2002-06-19 | 2009-01-22 | Palomar Medical Technologies, Inc. | Method And Apparatus For Photothermal Treatment Of Tissue At Depth |
US20090024192A1 (en) * | 2007-07-16 | 2009-01-22 | Spamedica International Srl | Method and device for minimally invasive skin and fat treatment |
US7647092B2 (en) * | 2002-04-05 | 2010-01-12 | Massachusetts Institute Of Technology | Systems and methods for spectroscopy of biological tissue |
US20100015576A1 (en) * | 2007-01-16 | 2010-01-21 | Rejuvedent Llc | Method and apparatus for diagnostic and treatment using hard tissue or material microperforation |
US20100021867A1 (en) * | 2006-11-27 | 2010-01-28 | Rejuvedent Llc | Method and apparatus for hard tissue treatment and modification |
Family Cites Families (1145)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US853033A (en) | 1906-07-11 | 1907-05-07 | Harvey H Roberts | Portable electric-light cabinet. |
US1590283A (en) | 1924-10-20 | 1926-06-29 | De Forest B Catlin | Therapeutic device |
BE346723A (en) | 1926-11-13 | |||
US1676183A (en) | 1927-05-03 | 1928-07-03 | Jacob N Garfunkle | Attachment for razors |
US2472385A (en) | 1946-07-18 | 1949-06-07 | Michael A Rollman | Massage device |
US3327712A (en) * | 1961-09-15 | 1967-06-27 | Ira H Kaufman | Photocoagulation type fiber optical surgical device |
US3261978A (en) | 1963-05-27 | 1966-07-19 | Henry S Brenman | Dental cleaning apparatus |
US3243650A (en) * | 1964-01-15 | 1966-03-29 | Ralph W Hawkins | Continuous ionization of flash lamps |
US3284665A (en) | 1964-01-29 | 1966-11-08 | Edgerton Germeshausen & Grier | Multiple electrode flashlamp circuit with a gas holdoff tube in circuit with a trigger electrode adjacent the anode |
US3651425A (en) * | 1964-12-22 | 1972-03-21 | Us Army | Multiple unit laser system |
US3524144A (en) | 1965-07-13 | 1970-08-11 | Us Army | Laser generator having a shock-induced narrow band illuminator |
US3465203A (en) | 1966-06-02 | 1969-09-02 | Xerox Corp | Flashlamp for electroscopic toner |
US3538919A (en) | 1967-04-07 | 1970-11-10 | Gregory System Inc | Depilation by means of laser energy |
US3527932A (en) * | 1967-11-16 | 1970-09-08 | James J Thomas | Transilluminating flashlight |
US3486070A (en) | 1968-04-29 | 1969-12-23 | Westinghouse Electric Corp | Solid-state constant power ballast for electric discharge device |
US3597652A (en) | 1969-01-14 | 1971-08-03 | Eg & G Inc | Apparatus for maintaining the temperature and operating a calibrated lamp in a constant resistance mode |
GB1251424A (en) | 1969-03-21 | 1971-10-27 | ||
US3622743A (en) | 1969-04-28 | 1971-11-23 | Hrand M Muncheryan | Laser eraser and microwelder |
US4456872A (en) | 1969-10-27 | 1984-06-26 | Bose Corporation | Current controlled two-state modulation |
US4038984A (en) | 1970-02-04 | 1977-08-02 | Electro Medical Systems, Inc. | Method and apparatus for high frequency electric surgery |
US3653778A (en) | 1970-04-16 | 1972-04-04 | John Robert Freiling | Applicator device for toothpaste dispensers or the like |
US3667454A (en) | 1970-06-12 | 1972-06-06 | Larry W Prince | Toothbrush with ultraviolet emitter |
US3693623A (en) * | 1970-12-25 | 1972-09-26 | Gregory System Inc | Photocoagulation means and method for depilation |
US3725733A (en) | 1971-04-19 | 1973-04-03 | Us Navy | Ultrafast multiple flashlamp |
US3699967A (en) | 1971-04-30 | 1972-10-24 | Valleylab Inc | Electrosurgical generator |
US3766488A (en) | 1971-06-17 | 1973-10-16 | Bell Telephone Labor Inc | Dye laser with pump cavity mode matched to laser resonator |
DE2145921C2 (en) | 1971-09-14 | 1982-05-06 | Günther Dr. 8022 Grünwald Nath | Device for material processing by means of a laser beam with a flexible light guide |
US3766393A (en) | 1971-11-22 | 1973-10-16 | Rca Corp | Optical data transmission system employing polarization-shift, multiple-cavity laser |
US3846811A (en) | 1972-03-29 | 1974-11-05 | Canon Kk | Flash unit for use with camera |
US3769963A (en) | 1972-03-31 | 1973-11-06 | L Goldman | Instrument for performing laser micro-surgery and diagnostic transillumination of living human tissue |
US3818914A (en) * | 1972-04-17 | 1974-06-25 | Spectroderm Inc | Apparatus and method for treatment of skin disorders |
FR2199453B1 (en) | 1972-05-12 | 1974-10-25 | Busser Francis | |
US3857015A (en) | 1972-11-08 | 1974-12-24 | O Richardson | Electrically heated heat sealing implement |
US3885569A (en) | 1972-11-21 | 1975-05-27 | Birtcher Corp | Electrosurgical unit |
US3818373A (en) | 1973-01-08 | 1974-06-18 | Gen Electric | Single pockels cell double pulsing scheme |
US3834391A (en) * | 1973-01-19 | 1974-09-10 | Block Carol Ltd | Method and apparatus for photoepilation |
US3815046A (en) | 1973-02-07 | 1974-06-04 | Atomic Energy Commission | Synchronously driven q-switched or q-switched-mode-locked laser oscillator |
US3821510A (en) | 1973-02-22 | 1974-06-28 | H Muncheryan | Hand held laser instrumentation device |
US3980861A (en) | 1973-03-26 | 1976-09-14 | Akio Fukunaga | Electrically heated miniature thermal implement |
US3909649A (en) | 1973-04-05 | 1975-09-30 | Gen Electric | Electric lamp with light-diffusing coating |
US3914709A (en) | 1973-05-14 | 1975-10-21 | Jersey Nuclear Avco Isotopes | Apparatus for lengthening laser output pulse duration |
US3890537A (en) | 1974-01-02 | 1975-06-17 | Gen Electric | Solid state chopper ballast for gaseous discharge lamps |
US3977083A (en) | 1974-02-05 | 1976-08-31 | Norman Leslie | Dental instrument |
US3900034A (en) * | 1974-04-10 | 1975-08-19 | Us Energy | Photochemical stimulation of nerves |
GB1485908A (en) | 1974-05-21 | 1977-09-14 | Nath G | Apparatus for applying light radiation |
DE2444893B2 (en) | 1974-09-19 | 1976-07-22 | Heimann Gmbh, 6200 Wiesbaden-Dotzheim | CIRCUIT ARRANGEMENT FOR IGNITING AT LEAST ONE GAS DISCHARGE FLASHING LAMP |
CA1086172A (en) | 1975-03-14 | 1980-09-23 | Robert F. Shaw | Surgical instrument having self-regulating radiant heating of its cutting edge and method of using the same |
US4065370A (en) | 1975-11-18 | 1977-12-27 | The United States Of America As Represented By The Secretary Of The Army | Method of ion plating a thin metallic strip for flashlamp starting |
US4019156A (en) | 1975-12-02 | 1977-04-19 | The United States Of America As Represented By The United States Energy Research And Development Administration | Active/passive mode-locked laser oscillator |
DE2609273A1 (en) | 1976-03-05 | 1977-09-08 | Mutzhas Maximilian F | IRRADIATION DEVICE WITH ULTRAVIOLET RADIATION SOURCE |
US4047106A (en) | 1976-06-01 | 1977-09-06 | Charles Elbert Robinson | Motor speed sensor |
US4273109A (en) * | 1976-07-06 | 1981-06-16 | Cavitron Corporation | Fiber optic light delivery apparatus and medical instrument utilizing same |
US4176324A (en) | 1976-09-20 | 1979-11-27 | Jersey Nuclear-Avco Isotopes, Inc. | High performance dye laser and flow channel therefor |
JPS5389293A (en) | 1977-01-14 | 1978-08-05 | Olympus Optical Co | High frequency cauterization power supply |
US4122853A (en) | 1977-03-14 | 1978-10-31 | Spectra-Med | Infrared laser photocautery device |
US4327729A (en) | 1977-06-27 | 1982-05-04 | The Procter & Gamble Company | Low-density disposable absorbent bandage having low stretch, wet strength center ply to provide improved pad integrity in use |
US4292601A (en) | 1977-06-29 | 1981-09-29 | Jersey Nuclear-Avco Isotopes, Inc. | Flashlamp excited fluid laser amplifier |
US6603988B2 (en) | 2001-04-13 | 2003-08-05 | Kelsey, Inc. | Apparatus and method for delivering ablative laser energy and determining the volume of tumor mass destroyed |
JPS6043134B2 (en) | 1977-08-25 | 1985-09-26 | 信紘 佐藤 | Device for measuring reflection characteristics of biological organs and tissues |
FR2402320A1 (en) | 1977-09-02 | 1979-03-30 | Anvar | LASER MODE SELECTOR |
US4294263A (en) | 1977-12-07 | 1981-10-13 | Air Shields, Inc. | System for detecting probe dislodgement |
US4228800A (en) | 1978-04-04 | 1980-10-21 | Concept, Inc. | Bipolar electrosurgical knife |
US4254333A (en) | 1978-05-31 | 1981-03-03 | Bergstroem Arne | Optoelectronic circuit element |
DE2826383A1 (en) | 1978-06-16 | 1979-12-20 | Eichler Juergen | Probe for laser surgery - is tubular and placed against or inserted in tissue, with or without heated end |
JPS6058982B2 (en) | 1978-10-13 | 1985-12-23 | 富士写真光機株式会社 | Photostimulation therapy device |
JPS5577187A (en) | 1978-12-05 | 1980-06-10 | Toshiba Corp | Laser oscillating device |
DE7906381U1 (en) | 1979-03-08 | 1979-07-12 | Richard Wolf Gmbh, 7134 Knittlingen | LIGHTING FOR OPERATIONAL AND EXAMINATION AREAS |
JPS55129327A (en) | 1979-03-28 | 1980-10-07 | Minolta Camera Co Ltd | Constant intensity light emitting strobe device |
US4269067A (en) | 1979-05-18 | 1981-05-26 | International Business Machines Corporation | Method and apparatus for focusing elastic waves converted from thermal energy |
US4302730A (en) | 1979-06-04 | 1981-11-24 | The United States Of America As Represented By The Secretary Of The Navy | Cavity dumper |
FR2465213A1 (en) | 1979-09-13 | 1981-03-20 | Oreal | APPARATUS FOR DIGITAL COLORING OR COLOR MODIFICATION OF AN OBJECT |
US4293827A (en) | 1979-09-14 | 1981-10-06 | Jersey Nuclear-Avco Isotopes, Inc. | Multiwavelength dye laser |
JPS56156150A (en) * | 1980-02-27 | 1981-12-02 | Nato Giyuntaa | Photocoagulator |
US4336809A (en) | 1980-03-17 | 1982-06-29 | Burleigh Instruments, Inc. | Human and animal tissue photoradiation system and method |
US4333197A (en) | 1980-06-02 | 1982-06-08 | Arthur Kuris | Ultrasonic toothbrush |
JPS574007A (en) | 1980-06-07 | 1982-01-09 | Takumi Tomijima | Multiple wavelength light communication system |
US4316467A (en) * | 1980-06-23 | 1982-02-23 | Lorenzo P. Maun | Control for laser hemangioma treatment system |
US4335726A (en) | 1980-07-11 | 1982-06-22 | The Kendall Company | Therapeutic device with temperature and pressure control |
US4375684A (en) * | 1980-07-28 | 1983-03-01 | Jersey Nuclear-Avco Isotopes, Inc. | Laser mode locking, Q-switching and dumping system |
US4435808A (en) | 1981-01-22 | 1984-03-06 | Ali Javan | Production of radiation at frequencies of preselected absorbing resonances and methods using same |
FR2498927A1 (en) | 1981-02-05 | 1982-08-06 | Javelle Edmond | APPARATUS FOR HANDLING THE ENERGY CIRCULATING IN THE MERIDIENS OF THE HUMAN BODY |
US4364015A (en) | 1981-03-12 | 1982-12-14 | Jersey Nuclear-Avco Isotopes, Inc. | Compact reservoir system for dye lasers |
US4388924A (en) * | 1981-05-21 | 1983-06-21 | Weissman Howard R | Method for laser depilation |
HU186081B (en) | 1981-09-02 | 1985-05-28 | Fenyo Marta | Process and apparatus for stimulating healing of pathologic points on the surface of the body first of all of wounds, ulcera and other epithelial lesions |
US4559943A (en) | 1981-09-03 | 1985-12-24 | C. R. Bard, Inc. | Electrosurgical generator |
US4445217A (en) | 1981-11-09 | 1984-04-24 | International Laser Systems, Inc. | Laser apparatus and method |
JPS5884482A (en) | 1981-11-13 | 1983-05-20 | Toshiba Corp | Pulse laser device |
JPS5886178A (en) | 1981-11-18 | 1983-05-23 | 松下電器産業株式会社 | Laser medical apparatus |
US4409479A (en) | 1981-12-03 | 1983-10-11 | Xerox Corporation | Optical cursor control device |
US4461294A (en) * | 1982-01-20 | 1984-07-24 | Baron Neville A | Apparatus and process for recurving the cornea of an eye |
US4555786A (en) | 1982-06-24 | 1985-11-26 | Board Of Trustees Of Leland Stanford, Jr. University | High power solid state laser |
GB2123287B (en) | 1982-07-09 | 1986-03-05 | Anna Gunilla Sutton | Depilaton device |
US4489415A (en) | 1982-07-12 | 1984-12-18 | General Electric Company | Pulse pumping an optically pumped laser |
US5363463A (en) | 1982-08-06 | 1994-11-08 | Kleinerman Marcos Y | Remote sensing of physical variables with fiber optic systems |
US5928222A (en) | 1982-08-06 | 1999-07-27 | Kleinerman; Marcos Y. | Fiber optic sensing techniques in laser medicine |
US4889525A (en) | 1982-08-17 | 1989-12-26 | Adamantech, Inc. | Sensitization of hypoxic tumor cells and control of growth thereof |
AU553836B2 (en) | 1982-08-27 | 1986-07-31 | Alistair Joseph Blake | Lamp for irradiating tumours |
US4452081A (en) | 1982-09-30 | 1984-06-05 | Varian Associates, Inc. | Measurement of velocity and tissue temperature by ultrasound |
US4784135A (en) | 1982-12-09 | 1988-11-15 | International Business Machines Corporation | Far ultraviolet surgical and dental procedures |
US4813412A (en) | 1982-12-28 | 1989-03-21 | Ya-Man Ltd. | Automatic system for an epilator device |
US4504727A (en) | 1982-12-30 | 1985-03-12 | International Business Machines Corporation | Laser drilling system utilizing photoacoustic feedback |
GB8302997D0 (en) | 1983-02-03 | 1983-03-09 | Bergstrom A | Electromagnetic radiation circuit element |
DE3304230A1 (en) | 1983-02-08 | 1984-08-16 | ams Automatische Meß- und Steuerungstechnik GmbH, 8572 Auerbach | RADIATION DEVICE |
US4576177A (en) | 1983-02-18 | 1986-03-18 | Webster Wilton W Jr | Catheter for removing arteriosclerotic plaque |
US5527368C1 (en) | 1983-03-11 | 2001-05-08 | Norton Co | Coated abrasives with rapidly curable adhesives |
US4524289A (en) | 1983-04-11 | 1985-06-18 | Xerox Corporation | Flash lamp power supply with reduced capacitance requirements |
US4601753A (en) | 1983-05-05 | 1986-07-22 | General Electric Company | Powdered iron core magnetic devices |
US4591762A (en) | 1983-05-31 | 1986-05-27 | Olympus Optical, Co. | Electronic flash |
US4662368A (en) | 1983-06-13 | 1987-05-05 | Trimedyne Laser Systems, Inc. | Localized heat applying medical device |
US4773413A (en) | 1983-06-13 | 1988-09-27 | Trimedyne Laser Systems, Inc. | Localized heat applying medical device |
US4503854A (en) | 1983-06-16 | 1985-03-12 | Jako Geza J | Laser surgery |
GB8320639D0 (en) | 1983-07-30 | 1983-09-01 | Emi Plc Thorn | Incandescent lamps |
JPS60123818A (en) * | 1983-12-08 | 1985-07-02 | Olympus Optical Co Ltd | Optical transmitter |
US4512197A (en) | 1983-09-01 | 1985-04-23 | The United States Of America As Represented By The Secretary Of The Navy | Apparatus for generating a focusable and scannable ultrasonic beam for non-destructive examination |
US4608978A (en) | 1983-09-26 | 1986-09-02 | Carol Block Limited | Method and apparatus for photoepiltion |
US5140984A (en) * | 1983-10-06 | 1992-08-25 | Proclosure, Inc. | Laser healing method and apparatus |
US5409479A (en) | 1983-10-06 | 1995-04-25 | Premier Laser Systems, Inc. | Method for closing tissue wounds using radiative energy beams |
US4862888A (en) | 1983-10-28 | 1989-09-05 | Bausch & Lomb Incorporated | Laser system |
US5108388B1 (en) * | 1983-12-15 | 2000-09-19 | Visx Inc | Laser surgery method |
JPS60148566A (en) | 1984-01-13 | 1985-08-05 | 株式会社東芝 | Laser treatment apparatus |
US4608979A (en) | 1984-02-22 | 1986-09-02 | Washington Research Foundation | Apparatus for the noninvasive shock fragmentation of renal calculi |
US4569345A (en) * | 1984-02-29 | 1986-02-11 | Aspen Laboratories, Inc. | High output electrosurgical unit |
US4724835A (en) * | 1984-03-06 | 1988-02-16 | Pain Suppression Labs, Inc. | Laser therapeutic device |
US4587968A (en) | 1984-03-19 | 1986-05-13 | Price David R | Electric emasculator and method for castrating |
US4592353A (en) | 1984-05-22 | 1986-06-03 | Surgical Laser Technologies Ohio, Inc. | Medical and surgical laser probe |
US4693244A (en) | 1984-05-22 | 1987-09-15 | Surgical Laser Technologies, Inc. | Medical and surgical laser probe I |
US4601037A (en) | 1984-06-13 | 1986-07-15 | Britt Corporation | Pulsed laser system |
IL75998A0 (en) | 1984-08-07 | 1985-12-31 | Medical Laser Research & Dev C | Laser system for providing target tissue specific energy deposition |
US4848339A (en) | 1984-09-17 | 1989-07-18 | Xintec Corporation | Laser heated intravascular cautery cap assembly |
US4994060A (en) * | 1984-09-17 | 1991-02-19 | Xintec Corporation | Laser heated cautery cap with transparent substrate |
US4566438A (en) * | 1984-10-05 | 1986-01-28 | Liese Grover J | Fiber-optic stylet for needle tip localization |
JPS62500626A (en) | 1984-10-25 | 1987-03-12 | キャンデラ・レ−ザ−・コ−ポレ−ション | Method and apparatus for amplifying light to generate a pulsed output beam of light |
US4677347A (en) | 1984-10-26 | 1987-06-30 | Olympus Optical, Co., Ltd. | Electronic flash |
US4656641A (en) | 1985-02-04 | 1987-04-07 | Xerox Corporation | Laser cavity optical system for stabilizing the beam from a phase locked multi-emitter broad emitter laser |
US4913142A (en) | 1985-03-22 | 1990-04-03 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
US5192278A (en) | 1985-03-22 | 1993-03-09 | Massachusetts Institute Of Technology | Multi-fiber plug for a laser catheter |
US5104392A (en) | 1985-03-22 | 1992-04-14 | Massachusetts Institute Of Technology | Laser spectro-optic imaging for diagnosis and treatment of diseased tissue |
US5318024A (en) | 1985-03-22 | 1994-06-07 | Massachusetts Institute Of Technology | Laser endoscope for spectroscopic imaging |
JP2615006B2 (en) | 1985-03-26 | 1997-05-28 | 富士写真光機 株式会社 | Laser beam side fiber |
US4819669A (en) * | 1985-03-29 | 1989-04-11 | Politzer Eugene J | Method and apparatus for shaving the beard |
US5346488A (en) | 1985-04-08 | 1994-09-13 | The General Hospital Corporation | Laser-induced ablation of atherosclerotic plaque |
US4887600A (en) | 1986-04-22 | 1989-12-19 | The General Hospital Corporation | Use of lasers to break down objects |
US4623929A (en) | 1985-05-03 | 1986-11-18 | Eastman Kodak Company | Flash tube simmer circuitry for a film video player electronic strobe light |
US4862886A (en) | 1985-05-08 | 1989-09-05 | Summit Technology Inc. | Laser angioplasty |
US4693556A (en) | 1985-06-04 | 1987-09-15 | Laser Therapeutics, Inc. | Apparatus for producing a spherical pattern of light and method of manufacture |
US4917084A (en) | 1985-07-31 | 1990-04-17 | C. R. Bard, Inc. | Infrared laser catheter system |
DE3686621T2 (en) | 1985-07-31 | 1993-02-25 | Bard Inc C R | INFRARED LASER CATHETER DEVICE. |
US5196004A (en) * | 1985-07-31 | 1993-03-23 | C. R. Bard, Inc. | Infrared laser catheter system |
US5484432A (en) | 1985-09-27 | 1996-01-16 | Laser Biotech, Inc. | Collagen treatment apparatus |
US5137530A (en) * | 1985-09-27 | 1992-08-11 | Sand Bruce J | Collagen treatment apparatus |
US4976709A (en) | 1988-12-15 | 1990-12-11 | Sand Bruce J | Method for collagen treatment |
GB2184021A (en) * | 1985-12-13 | 1987-06-17 | Micra Ltd | Laser treatment apparatus for port wine stains |
US4695697A (en) | 1985-12-13 | 1987-09-22 | Gv Medical, Inc. | Fiber tip monitoring and protection assembly |
US4910438A (en) | 1985-12-17 | 1990-03-20 | Hughes Aircraft Company | Wide band, high efficiency simmer power supply for a laser flashlamp |
FR2591902B1 (en) | 1985-12-23 | 1989-06-30 | Collin Yvon | EXTERNAL LASER THERAPY APPARATUS HAVING ONE OR MORE LASER DIODES IN SUCTION CUPS |
US4791927A (en) | 1985-12-26 | 1988-12-20 | Allied Corporation | Dual-wavelength laser scalpel background of the invention |
JPS62165985A (en) | 1986-01-17 | 1987-07-22 | Nec Corp | Laser oscillator stabilized at diverging angle of laser beam |
US4735201A (en) | 1986-01-30 | 1988-04-05 | The Beth Israel Hospital Association | Optical fiber with detachable metallic tip for intravascular laser coagulation of arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
US4759349A (en) | 1986-02-24 | 1988-07-26 | Vitalmetrics, Inc. | Surgical instrument having a heat sink for irrigation, aspiration, and illumination |
US4871479A (en) | 1986-03-25 | 1989-10-03 | Comurhex Societe Pour La Conversion De L'uranium En Metal Et Hexafluorure | Process for producing sintered mixed oxides which are soluble in nitric acid from solutions of nitrates |
US4775361A (en) | 1986-04-10 | 1988-10-04 | The General Hospital Corporation | Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport |
US5336217A (en) | 1986-04-24 | 1994-08-09 | Institut National De La Sante Et De La Recherche Medicale (Insepm) | Process for treatment by irradiating an area of a body, and treatment apparatus usable in dermatology for the treatment of cutaneous angio dysplasias |
CS258312B1 (en) | 1986-04-28 | 1988-08-16 | Karel Hamal | Laser's resonator with radiation frequency change |
FR2597744A1 (en) * | 1986-04-29 | 1987-10-30 | Boussignac Georges | CARDIO-VASCULAR CATHETER FOR LASER SHOOTING |
US4736743A (en) | 1986-05-12 | 1988-04-12 | Surgical Laser Technology, Inc. | Vaporization contact laser probe |
JPS6397175A (en) | 1986-10-15 | 1988-04-27 | 森 敬 | Light irradiation apparatus for emitting tooth germ treating light |
DE3719561C2 (en) | 1986-06-12 | 1998-12-10 | Morita Mfg | Medical light irradiation handpiece |
US4736745A (en) | 1986-06-27 | 1988-04-12 | University Of Cincinnati | Laser treatment of cancerization of the oral cavity and apparatus for use therewith |
KR900005856B1 (en) | 1986-06-30 | 1990-08-13 | 가부시끼가이샤 니혼 이요 레이저 겡뀨쇼 | Semiconductor laser therapeutic apparatus |
JPS6323648A (en) | 1986-07-17 | 1988-01-30 | 工業技術院長 | Light source device for cancer diagnostic or remedy apparatus |
US4926227A (en) * | 1986-08-01 | 1990-05-15 | Nanometrics Inc. | Sensor devices with internal packaged coolers |
JPH0744141B2 (en) | 1987-09-22 | 1995-05-15 | 株式会社ニコン | Lighting optics |
US4860743A (en) | 1986-10-27 | 1989-08-29 | University Of Florida | Laser method and apparatus for the recanalization of vessels and the treatment of other cardiac conditions |
US5041109A (en) | 1986-10-27 | 1991-08-20 | University Of Florida | Laser apparatus for the recanalization of vessels and the treatment of other cardiac conditions |
EP0268019A1 (en) | 1986-11-13 | 1988-05-25 | Messerschmitt-Bölkow-Blohm Gesellschaft mit beschränkter Haftung | Apparatus for disintegrating a fluid-suspended solid body |
DE3643284A1 (en) | 1986-12-18 | 1988-06-30 | Aesculap Ag | METHOD AND DEVICE FOR CUTTING A MATERIAL BY MEANS OF A LASER BEAM |
US4779173A (en) | 1986-12-24 | 1988-10-18 | Carr Charlie O | Illuminated brush device |
US4840563A (en) | 1987-02-26 | 1989-06-20 | Siemens Aktiengesellschaft | Dental equipment having means for delivering RF and LF energy to a dental handpiece |
US5057099A (en) | 1987-02-27 | 1991-10-15 | Xintec Corporation | Method for laser surgery |
US5092865A (en) | 1987-02-27 | 1992-03-03 | Xintec Corporation | Optical fiber fault detector |
JPS63216579A (en) | 1987-03-05 | 1988-09-08 | 大工園 則雄 | Laser beam irradiation apparatus for hyperthermia |
JPS63249577A (en) | 1987-04-06 | 1988-10-17 | 浜理薬品工業株式会社 | Permanent hair removing method, preparation and device |
DE8705296U1 (en) | 1987-04-09 | 1988-08-04 | Heimann Gmbh, 6200 Wiesbaden, De | |
US4749913A (en) | 1987-04-17 | 1988-06-07 | General Electric Company | Operating circuit for a direct current discharge lamp |
US4901323A (en) * | 1987-05-01 | 1990-02-13 | Universities Research Association, Inc. | Laser pulse stretcher method and apparatus |
US4745909A (en) | 1987-05-15 | 1988-05-24 | Pelton Robert J | Cold massage tool and method of use thereof |
JPS6427554A (en) | 1987-07-22 | 1989-01-30 | Morita Mfg | Medical laser irradiation apparatus |
JPH01178256A (en) | 1988-01-05 | 1989-07-14 | Hideo Suyama | Electronic toothbrush |
EP0311295A3 (en) | 1987-10-07 | 1990-02-28 | University College London | Improvements in surgical apparatus |
US4862903A (en) | 1987-10-09 | 1989-09-05 | U.S. Divers Company, Inc. | Breathing mouthpiece for contacting upper palate and lower jaw of user's mouth |
JPH0199574A (en) | 1987-10-13 | 1989-04-18 | Matsushita Electric Ind Co Ltd | Medical equipment with semiconductor laser |
US4860744A (en) * | 1987-11-02 | 1989-08-29 | Raj K. Anand | Thermoelectrically controlled heat medical catheter |
IL84367A (en) | 1987-11-04 | 1994-02-27 | Amcor Ltd | Apparatus for use in radiation therapy |
US4930504A (en) | 1987-11-13 | 1990-06-05 | Diamantopoulos Costas A | Device for biostimulation of tissue and method for treatment of tissue |
US4845608A (en) | 1987-12-21 | 1989-07-04 | General Electric Company | Digital speed controller using a single-chip microcontroller |
JPH01181877A (en) | 1988-01-14 | 1989-07-19 | Matsushita Electric Ind Co Ltd | Laser medical treatment device |
US4860172A (en) * | 1988-01-19 | 1989-08-22 | Biotronics Associates, Inc. | Lamp-based laser simulator |
US5112328A (en) | 1988-01-25 | 1992-05-12 | Refractive Laser Research & Development Program, Ltd. | Method and apparatus for laser surgery |
US4931053A (en) | 1988-01-27 | 1990-06-05 | L'esperance Medical Technologies, Inc. | Method and apparatus for enhanced vascular or other growth |
US4898439A (en) * | 1988-02-10 | 1990-02-06 | Kei Mori | Light radiation device for use in medical treatment |
US4813762A (en) | 1988-02-11 | 1989-03-21 | Massachusetts Institute Of Technology | Coherent beam combining of lasers using microlenses and diffractive coupling |
US4977571A (en) | 1988-03-29 | 1990-12-11 | Candela Laser Corporation | Dye laser solution circulation system |
US5201731A (en) | 1988-03-30 | 1993-04-13 | Hakky Said I | Laser resectoscope with ultransonic imaging means |
US4955882A (en) | 1988-03-30 | 1990-09-11 | Hakky Said I | Laser resectoscope with mechanical and laser cutting means |
US5061266A (en) | 1988-03-30 | 1991-10-29 | Hakky Said I | Laser resectoscope and method |
EP0413025A4 (en) | 1988-06-04 | 1991-05-22 | Sumitomo Electric Industries, Ltd | Laser-aided intravascular operation equipment |
JPH022199A (en) | 1988-06-14 | 1990-01-08 | Toshiba Corp | Dye circulator of dye laser |
DE8807746U1 (en) | 1988-06-15 | 1988-09-29 | Messerschmitt-Boelkow-Blohm Gmbh, 8012 Ottobrunn, De | |
JPH0734542B2 (en) | 1988-06-29 | 1995-04-12 | 日本電気株式会社 | D-A conversion circuit |
JPH0213479A (en) * | 1988-07-01 | 1990-01-17 | Takashi Mori | Light radiation device for medical therapy |
US4884560A (en) | 1988-07-11 | 1989-12-05 | Kuracina Thomas C | Thermal massage device |
GB8816648D0 (en) | 1988-07-13 | 1988-08-17 | Rowland A C | Light delivery system |
US4890898A (en) * | 1988-08-18 | 1990-01-02 | Hgm Medical Laser Systems, Inc. | Composite microsize optical fiber-electric lead cable |
US5037421A (en) | 1989-10-06 | 1991-08-06 | Coherent, Inc., Medical Group | Mid-infrared laser arthroscopic procedure |
US4878224A (en) | 1988-09-16 | 1989-10-31 | Hoechst Celanese Corporation | Dye lasers |
US4928038A (en) | 1988-09-26 | 1990-05-22 | General Electric Company | Power control circuit for discharge lamp and method of operating same |
JPH0288080A (en) | 1988-09-26 | 1990-03-28 | Takashi Mori | Light irradiation medical curing tool |
US5191883A (en) | 1988-10-28 | 1993-03-09 | Prutech Research And Development Partnership Ii | Device for heating tissue in a patient's body |
DE3837248A1 (en) | 1988-10-28 | 1990-05-03 | Teichmann Heinrich Otto Dr Phy | Device for treating skin lesions |
EP0368512A3 (en) | 1988-11-10 | 1990-08-08 | Premier Laser Systems, Inc. | Multiwavelength medical laser system |
DE3841503A1 (en) | 1988-12-09 | 1990-06-28 | Wrobel Walter G Dr | Method and device for removing dental tissue |
JP2683565B2 (en) | 1988-12-12 | 1997-12-03 | 則雄 大工園 | Laser light transmitting body and method of manufacturing the same |
JPH02174804A (en) | 1988-12-27 | 1990-07-06 | Hiroshi Fukuba | Toothbrush device of mouth lightening type |
US4860303A (en) | 1989-01-17 | 1989-08-22 | The United States Of America As Represented By The Secretary Of The Army | Double-sided co-axial laser |
JP2592791B2 (en) | 1989-01-31 | 1997-03-19 | 株式会社サンギ | Electronic toothbrush |
US5006293A (en) | 1989-02-02 | 1991-04-09 | Owens-Corning Fiberglas Corporation | Process for forming flat plate ballistic resistant materials |
JP2779825B2 (en) | 1989-02-15 | 1998-07-23 | 則雄 大工園 | Laser light emitting device |
US5425735A (en) | 1989-02-22 | 1995-06-20 | Psi Medical Products, Inc. | Shielded tip catheter for lithotripsy |
EP0387754A1 (en) | 1989-03-17 | 1990-09-19 | Schott Glaswerke | Catheter system to introduce laserbeams into bloodvessels of the human body |
US4945239A (en) * | 1989-03-29 | 1990-07-31 | Center For Innovative Technology | Early detection of breast cancer using transillumination |
US5207576A (en) | 1989-04-07 | 1993-05-04 | American Dental Laser, Inc. | Dental laser assembly with dual lasers |
US5009658A (en) | 1989-04-14 | 1991-04-23 | Karl Storz Endoscopy-America, Inc. | Dual frequency laser lithotripter |
US5421337A (en) | 1989-04-14 | 1995-06-06 | Massachusetts Institute Of Technology | Spectral diagnosis of diseased tissue |
US5263951A (en) | 1989-04-21 | 1993-11-23 | Kerus Medical Systems | Correction of the optical focusing system of the eye using laser thermal keratoplasty |
JPH02285694A (en) | 1989-04-26 | 1990-11-22 | Toshiba Corp | Dye laser |
DE69027678T2 (en) | 1989-05-03 | 1997-02-20 | Medical Technologies Inc Enter | INSTRUMENT FOR INTRALUMINAL RELIEF OF STENOSES |
CN2053926U (en) | 1989-05-06 | 1990-03-07 | 李杰生 | Radiation treatment apparatus |
US5057104A (en) * | 1989-05-30 | 1991-10-15 | Cyrus Chess | Method and apparatus for treating cutaneous vascular lesions |
US5207673A (en) | 1989-06-09 | 1993-05-04 | Premier Laser Systems, Inc. | Fiber optic apparatus for use with medical lasers |
JPH0319385A (en) | 1989-06-16 | 1991-01-28 | Mitsubishi Electric Corp | Dye laser device |
JP2752439B2 (en) | 1989-06-20 | 1998-05-18 | 株式会社リコー | Image output method |
US5011483A (en) | 1989-06-26 | 1991-04-30 | Dennis Sleister | Combined electrosurgery and laser beam delivery device |
JPH0627172Y2 (en) | 1989-07-04 | 1994-07-27 | 東京医研株式会社 | Infrared treatment device for physical examination |
FR2650196B1 (en) | 1989-07-06 | 1991-12-06 | Technomed Internat | METHOD AND APPARATUS FOR REGENERATING A DYE SOLUTION IN A DILUENT, IN PARTICULAR A DYE SOLUTION FOR A DYE LASER |
US4973848A (en) | 1989-07-28 | 1990-11-27 | J. Mccaughan | Laser apparatus for concurrent analysis and treatment |
US5955490A (en) | 1989-07-28 | 1999-09-21 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
JP2854027B2 (en) | 1989-08-03 | 1999-02-03 | ヤーマン株式会社 | Light hair removal device |
JPH0373106A (en) | 1989-08-14 | 1991-03-28 | Omron Corp | Optical medical toothbrush |
WO1991002562A1 (en) | 1989-08-17 | 1991-03-07 | Surgical Laser Products, Inc. | Integral end structure for medical laser waveguide |
JP2882814B2 (en) | 1989-08-24 | 1999-04-12 | 株式会社エス・エル・ティ・ジャパン | Laser irradiation equipment |
JP3069108B2 (en) | 1989-09-01 | 2000-07-24 | 株式会社エス・エル・ティ・ジャパン | Laser light emitting device |
JP3046315B2 (en) | 1989-09-05 | 2000-05-29 | 株式会社エス・エル・ティ・ジャパン | Laser irradiation equipment |
US4972427A (en) | 1989-09-14 | 1990-11-20 | Spectra Diode Laboratories, Inc. | Talbot cavity diode laser with uniform single-mode output |
US4992256A (en) | 1989-09-27 | 1991-02-12 | Colgate-Palmolive Company | Plaque disclosing compositions |
US5404001A (en) | 1992-10-08 | 1995-04-04 | Bard; Simon | Fiber optic barcode reader |
US5027359A (en) | 1989-10-30 | 1991-06-25 | Massachusetts Institute Of Technology | Miniature Talbot cavity for lateral mode control of laser array |
DE3936367A1 (en) * | 1989-11-02 | 1991-05-08 | Simon Pal | SHAVER |
US5369496A (en) | 1989-11-13 | 1994-11-29 | Research Foundation Of City College Of New York | Noninvasive method and apparatus for characterizing biological materials |
US5129896A (en) | 1989-11-13 | 1992-07-14 | Hasson Harrith M | Holder to facilitate use of a laser in surgical procedures |
US4979180A (en) | 1989-11-24 | 1990-12-18 | Muncheryan Arthur M | Modular interchangeable laser system |
GB2239675A (en) | 1989-12-05 | 1991-07-10 | Man Fai Shiu | Pump for pumping liquid |
JPH03183184A (en) | 1989-12-13 | 1991-08-09 | Toshiba Corp | Monitor for dye deterioration of ring dye laser oscillator |
FR2655849B1 (en) | 1989-12-19 | 1997-10-31 | Raymond Bontemps | LOCAL CRYOGENIC DEVICE FOR MASSAGE OF THE SKIN. |
JP3148216B2 (en) | 1990-01-22 | 2001-03-19 | 株式会社エス・エル・ティ・ジャパン | Treatment equipment by laser beam irradiation |
US5261904A (en) | 1990-01-30 | 1993-11-16 | C. R. Bard, Inc. | Laser catheter having diffraction grating for beam shaping |
US5032178A (en) | 1990-02-02 | 1991-07-16 | Demetron Research Corporation | Dental composition system and method for bleaching teeth |
GB2242307B (en) | 1990-02-09 | 1994-09-07 | Omega Universal Tech Ltd | Laser probe for biomodulation of tissue nerve and immune systems |
US4976308A (en) | 1990-02-21 | 1990-12-11 | Wright State University | Thermal energy storage heat exchanger |
US5102410A (en) | 1990-02-26 | 1992-04-07 | Dressel Thomas D | Soft tissue cutting aspiration device and method |
AU7463991A (en) | 1990-03-14 | 1991-10-10 | Candela Laser Corporation | Apparatus and method of treating pigmented lesions using pulsed irradiation |
US5147353A (en) | 1990-03-23 | 1992-09-15 | Myriadlase, Inc. | Medical method for applying high energy light and heat for gynecological sterilization procedures |
SE465953B (en) * | 1990-04-09 | 1991-11-25 | Morgan Gustafsson | DEVICE FOR TREATMENT OF UNDESECTED EXTERNAL ACCOMMODATIONS |
US5059192A (en) | 1990-04-24 | 1991-10-22 | Nardo Zaias | Method of hair depilation |
US5071416A (en) | 1990-05-02 | 1991-12-10 | Metalaser Technologies, Inc. | Method of and apparatus for laser-assisted therapy |
JP2917413B2 (en) | 1990-05-23 | 1999-07-12 | ソニー株式会社 | Solid state laser oscillator |
US5060243A (en) | 1990-05-29 | 1991-10-22 | Motorola, Inc. | Ripple counter with reverse-propagated zero detection |
GB9011998D0 (en) | 1990-05-30 | 1990-07-18 | Omega Universal Tech Ltd | A device and method for laser photothermotherapy |
US5725522A (en) | 1990-06-15 | 1998-03-10 | Rare Earth Medical, Inc. | Laser suturing of biological materials |
US5071417A (en) | 1990-06-15 | 1991-12-10 | Rare Earth Medical Lasers, Inc. | Laser fusion of biological materials |
AU642266B2 (en) | 1990-06-25 | 1993-10-14 | Kevin John Bourke | Method and apparatus for dental treatment |
US5197470A (en) | 1990-07-16 | 1993-03-30 | Eastman Kodak Company | Near infrared diagnostic method and instrument |
US5046494A (en) | 1990-08-27 | 1991-09-10 | John Searfoss | Phototherapy method |
US5312396A (en) | 1990-09-06 | 1994-05-17 | Massachusetts Institute Of Technology | Pulsed laser system for the surgical removal of tissue |
DE4032860A1 (en) | 1990-10-12 | 1992-04-16 | Zeiss Carl Fa | POWER-CONTROLLED CONTACT APPLICATOR FOR LASER RADIATION |
DE4032471C2 (en) | 1990-10-12 | 1997-02-06 | Delma Elektro Med App | Electrosurgical device |
US5472748A (en) | 1990-10-15 | 1995-12-05 | The United States Of America As Represented By The United States Department Of Energy | Permanent laser conditioning of thin film optical materials |
US5190541A (en) | 1990-10-17 | 1993-03-02 | Boston Scientific Corporation | Surgical instrument and method |
US5354324A (en) | 1990-10-18 | 1994-10-11 | The General Hospital Corporation | Laser induced platelet inhibition |
US5269777A (en) | 1990-11-01 | 1993-12-14 | Pdt Systems, Inc. | Diffusion tip for optical fibers |
US5257991A (en) | 1990-11-15 | 1993-11-02 | Laserscope | Instrumentation for directing light at an angle |
US5549660A (en) | 1990-11-15 | 1996-08-27 | Amron, Ltd. | Method of treating acne |
US5109387A (en) | 1990-12-26 | 1992-04-28 | Garden Jerome M | Dye laser system and method |
US5056515A (en) | 1991-01-04 | 1991-10-15 | Abel Elaine R | Tracheostomy tube assembly |
DE4100442C2 (en) | 1991-01-09 | 1994-02-10 | Texas Instruments Deutschland | Arrangement for monitoring operating parameters of pneumatic tires of a vehicle mounted on wheel rims |
US5090019A (en) * | 1991-01-10 | 1992-02-18 | The United States Of America As Represented By The Secretary Of The Navy | Laser diode-pumped tunable solid state laser |
US5065515A (en) | 1991-01-24 | 1991-11-19 | Warner-Lambert Company | Thermally assisted shaving system |
US6405072B1 (en) | 1991-01-28 | 2002-06-11 | Sherwood Services Ag | Apparatus and method for determining a location of an anatomical target with reference to a medical apparatus |
US5300097A (en) * | 1991-02-13 | 1994-04-05 | Lerner Ethan A | Fiber optic psoriasis treatment device |
US5132980A (en) | 1991-02-13 | 1992-07-21 | Coherent, Inc. | Method and device for preconditioning a laser having a solid state gain medium |
US5163935A (en) | 1991-02-20 | 1992-11-17 | Reliant Laser Corporation | Surgical laser endoscopic focusing guide with an optical fiber link |
DE9102407U1 (en) | 1991-02-28 | 1991-07-11 | Mink, Mathias, 7570 Baden-Baden, De | |
IL97531A (en) | 1991-03-12 | 1995-12-31 | Kelman Elliot | Hair cutting apparatus |
US5492894A (en) * | 1991-03-21 | 1996-02-20 | The Procter & Gamble Company | Compositions for treating wrinkles comprising a peptide |
US5369831A (en) | 1991-03-25 | 1994-12-06 | Sonex International Corporation | Therapeutic ultrasonic toothbrush |
US5207671A (en) * | 1991-04-02 | 1993-05-04 | Franken Peter A | Laser debridement of wounds |
US5147356A (en) | 1991-04-16 | 1992-09-15 | Microsurge, Inc. | Surgical instrument |
US5242438A (en) | 1991-04-22 | 1993-09-07 | Trimedyne, Inc. | Method and apparatus for treating a body site with laterally directed laser radiation |
GB9108777D0 (en) | 1991-04-24 | 1991-06-12 | Vuman Ltd | A dermatological laser |
US6485413B1 (en) | 1991-04-29 | 2002-11-26 | The General Hospital Corporation | Methods and apparatus for forward-directed optical scanning instruments |
US5300063A (en) | 1991-05-11 | 1994-04-05 | Nidek Co., Ltd. | Ophthalmic laser apparatus |
US5140608A (en) | 1991-05-29 | 1992-08-18 | Optrotech Ltd, Israel Company | Optical system for focusing a light beam on to an image plane |
DE4118610A1 (en) | 1991-06-06 | 1992-12-10 | Siemens Ag | Coupling device for introducing acoustic waves into the body of a living being |
JP3274691B2 (en) | 1991-06-14 | 2002-04-15 | 並木精密宝石株式会社 | Manufacturing method of optical fiber terminal with micro lens |
RU2122848C1 (en) | 1991-06-24 | 1998-12-10 | Учебно-научно-производственный лазерный центр Санкт-Петербургского института точной механики и оптики | Reflexotherapy device |
US5249192A (en) | 1991-06-27 | 1993-09-28 | Laserscope | Multiple frequency medical laser |
US5320620A (en) | 1991-07-01 | 1994-06-14 | Laser Centers Of America | Laser surgical device with blunt flat-sided energy-delivery element |
DE4122219A1 (en) | 1991-07-04 | 1993-01-07 | Delma Elektro Med App | ELECTRO-SURGICAL TREATMENT INSTRUMENT |
US5474549A (en) | 1991-07-09 | 1995-12-12 | Laserscope | Method and system for scanning a laser beam for controlled distribution of laser dosage |
US5331649A (en) | 1991-07-10 | 1994-07-19 | Alson Surgical, Inc. | Multiple wavelength laser system |
US5159601A (en) | 1991-07-17 | 1992-10-27 | General Instrument Corporation | Method for producing a tunable erbium fiber laser |
US5217455A (en) | 1991-08-12 | 1993-06-08 | Tan Oon T | Laser treatment method for removing pigmentations, lesions, and abnormalities from the skin of a living human |
JP2754964B2 (en) | 1991-08-13 | 1998-05-20 | 日本電気株式会社 | Multi-pole connector mating structure |
US5254114A (en) | 1991-08-14 | 1993-10-19 | Coherent, Inc. | Medical laser delivery system with internally reflecting probe and method |
US5370649A (en) | 1991-08-16 | 1994-12-06 | Myriadlase, Inc. | Laterally reflecting tip for laser transmitting fiber |
US5225926A (en) * | 1991-09-04 | 1993-07-06 | International Business Machines Corporation | Durable optical elements fabricated from free standing polycrystalline diamond and non-hydrogenated amorphous diamond like carbon (dlc) thin films |
US5267399A (en) | 1991-09-09 | 1993-12-07 | Johnston William A | Implement for simultaneous skin chilling and chilled gel application |
US5171564A (en) | 1991-09-13 | 1992-12-15 | Colgate-Palmolive | Aqueous tooth whitening dentifrice |
US5370642A (en) | 1991-09-25 | 1994-12-06 | Keller; Gregory S. | Method of laser cosmetic surgery |
AU2414392A (en) | 1991-09-26 | 1993-04-27 | Warner-Lambert Company | Hair ablation system by optical irradiation |
US5255277A (en) | 1991-09-30 | 1993-10-19 | Whittaker Ordnance, Inc. | Electronic pulse width controller for flashlamp pumped lasers |
US5293880A (en) | 1991-10-02 | 1994-03-15 | Levitt Steven J | Athletic mouthguard |
US5222953A (en) | 1991-10-02 | 1993-06-29 | Kambiz Dowlatshahi | Apparatus for interstitial laser therapy having an improved temperature sensor for tissue being treated |
US5439954A (en) | 1991-10-11 | 1995-08-08 | The Procter & Gamble Company | Substituted phenyl-1,3-diketones as protectants against skin damage |
US6461296B1 (en) | 1998-06-26 | 2002-10-08 | 2000 Injectx, Inc. | Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells |
US5425728A (en) * | 1991-10-29 | 1995-06-20 | Tankovich; Nicolai I. | Hair removal device and method |
US5871480A (en) | 1991-10-29 | 1999-02-16 | Thermolase Corporation | Hair removal using photosensitizer and laser |
US5817089A (en) | 1991-10-29 | 1998-10-06 | Thermolase Corporation | Skin treatment process using laser |
US5226907A (en) * | 1991-10-29 | 1993-07-13 | Tankovich Nikolai I | Hair removal device and method |
US5423803A (en) | 1991-10-29 | 1995-06-13 | Thermotrex Corporation | Skin surface peeling process using laser |
US5213092A (en) | 1991-10-31 | 1993-05-25 | Martin Uram | Aspirating endoscope |
US5303585A (en) | 1991-10-31 | 1994-04-19 | Jtl Medical Corporation | Fluid volume sensor |
CA2106410C (en) | 1991-11-08 | 2004-07-06 | Stuart D. Edwards | Ablation electrode with insulated temperature sensing elements |
US7198046B1 (en) | 1991-11-14 | 2007-04-03 | Wake Forest University Health Sciences | Wound treatment employing reduced pressure |
DE4138116A1 (en) | 1991-11-19 | 1993-06-03 | Delma Elektro Med App | MEDICAL HIGH-FREQUENCY COAGULATION CUTTER |
US5344418A (en) * | 1991-12-12 | 1994-09-06 | Shahriar Ghaffari | Optical system for treatment of vascular lesions |
US5246436A (en) | 1991-12-18 | 1993-09-21 | Alcon Surgical, Inc. | Midinfrared laser tissue ablater |
US5275596A (en) * | 1991-12-23 | 1994-01-04 | Laser Centers Of America | Laser energy delivery tip element with throughflow of vaporized materials |
US5219347A (en) | 1991-12-24 | 1993-06-15 | Laser Engineering, Inc. | Decoupled dual-beam control system |
CN1073607A (en) | 1991-12-28 | 1993-06-30 | 王文辉 | Electrotherapeutic toothbrush |
IL100545A (en) | 1991-12-29 | 1995-03-15 | Dimotech Ltd | Apparatus for photodynamic therapy treatment |
US5501680A (en) | 1992-01-15 | 1996-03-26 | The University Of Pittsburgh | Boundary and proximity sensor apparatus for a laser |
US5353790A (en) | 1992-01-17 | 1994-10-11 | Board Of Regents, The University Of Texas System | Method and apparatus for optical measurement of bilirubin in tissue |
US5830209A (en) | 1992-02-05 | 1998-11-03 | Angeion Corporation | Multi-fiber laser catheter |
WO1993015676A1 (en) | 1992-02-05 | 1993-08-19 | Angelase, Inc. | Laser catheter with movable integral fixation wire |
US5160194A (en) | 1992-02-27 | 1992-11-03 | Feldman Melvin D | Toothbrush with externally illuminated bristles |
US5591219A (en) | 1992-03-06 | 1997-01-07 | Dungan; Thomas E. | Frequency modulator |
DE4207463C2 (en) | 1992-03-10 | 1996-03-28 | Siemens Ag | Arrangement for the therapy of tissue with ultrasound |
GB2270159A (en) | 1992-03-13 | 1994-03-02 | Scient Generics Ltd | Optically controlled ultrasound array |
CA2158739C (en) | 1992-03-20 | 2004-09-21 | R. Rox Anderson | Laser illuminator |
DE9204621U1 (en) | 1992-04-03 | 1992-07-30 | Oralia Dentalprodukte Gmbh, 7750 Konstanz, De | |
US5257970A (en) | 1992-04-09 | 1993-11-02 | Health Research, Inc. | In situ photodynamic therapy |
CA2093055C (en) | 1992-04-09 | 2002-02-19 | Shimon Eckhouse | Method and apparatus for therapeutic electromagnetic treatment |
US5540681A (en) | 1992-04-10 | 1996-07-30 | Medtronic Cardiorhythm | Method and system for radiofrequency ablation of tissue |
US5349590A (en) | 1992-04-10 | 1994-09-20 | Premier Laser Systems, Inc. | Medical laser apparatus for delivering high power infrared light |
US5284153A (en) * | 1992-04-14 | 1994-02-08 | Brigham And Women's Hospital | Method for locating a nerve and for protecting nerves from injury during surgery |
US5287372A (en) | 1992-04-24 | 1994-02-15 | Hughes Aircraft Company | Quasi-resonant diode drive current source |
US5755752A (en) | 1992-04-24 | 1998-05-26 | Segal; Kim Robin | Diode laser irradiation system for biological tissue stimulation |
CA2134479C (en) | 1992-04-30 | 2007-09-04 | Michael Wilson | Laser treatment |
US5308311A (en) | 1992-05-01 | 1994-05-03 | Robert F. Shaw | Electrically heated surgical blade and methods of making |
WO1993021843A1 (en) | 1992-05-05 | 1993-11-11 | Coherent, Inc. | Device and method for variably blending multiple laser beams for medical purposes |
ATE155933T1 (en) | 1992-05-06 | 1997-08-15 | Electrox Ltd | SYSTEM FOR COMBINING LASER BEAMS |
US5334191A (en) * | 1992-05-21 | 1994-08-02 | Dix Phillip Poppas | Laser tissue welding control system |
US5507739A (en) | 1992-06-15 | 1996-04-16 | American Dental Technologies, Inc. | Dental laser |
US5290274A (en) | 1992-06-16 | 1994-03-01 | Laser Medical Technology, Inc. | Laser apparatus for medical and dental treatments |
JPH0622871A (en) | 1992-07-03 | 1994-02-01 | Hideyo Niida | Toothbrush case with sterilamp |
US5292320A (en) | 1992-07-06 | 1994-03-08 | Ceramoptec, Inc. | Radial medical laser delivery device |
EP0920840A3 (en) | 1992-07-31 | 2000-03-29 | Molten Corporation | Small-sized light irradiator for dental use |
US5596619A (en) | 1992-08-21 | 1997-01-21 | Nomos Corporation | Method and apparatus for conformal radiation therapy |
CA2143639C (en) * | 1992-09-01 | 2004-07-20 | Edwin L. Adair | Sterilizable endoscope with separable disposable tube assembly |
US5267995A (en) | 1992-09-01 | 1993-12-07 | Pdt Systems | Optical waveguide with flexible tip |
DE69311478T2 (en) | 1992-09-07 | 1998-01-02 | Philips Electronics Nv | Method for producing a block-shaped carrier body for a semiconductor component |
DE4232915A1 (en) | 1992-10-01 | 1994-04-07 | Hohla Kristian | Device for shaping the cornea by removing tissue |
US5336221A (en) | 1992-10-14 | 1994-08-09 | Premier Laser Systems, Inc. | Method and apparatus for applying thermal energy to tissue using a clamp |
US5306143A (en) | 1992-10-15 | 1994-04-26 | Laser Medical Technology, Inc. | Dental hygiene appliance |
US5423800A (en) | 1992-10-19 | 1995-06-13 | The University Of Miami | Laser scleral buckling method and instruments therefor |
US5620478A (en) * | 1992-10-20 | 1997-04-15 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5683380A (en) | 1995-03-29 | 1997-11-04 | Esc Medical Systems Ltd. | Method and apparatus for depilation using pulsed electromagnetic radiation |
US6280438B1 (en) | 1992-10-20 | 2001-08-28 | Esc Medical Systems Ltd. | Method and apparatus for electromagnetic treatment of the skin, including hair depilation |
US5626631A (en) * | 1992-10-20 | 1997-05-06 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US5720772A (en) * | 1992-10-20 | 1998-02-24 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
WO1994009694A1 (en) | 1992-10-28 | 1994-05-11 | Arsenault, Dennis, J. | Electronic endoscope |
US5300065A (en) | 1992-11-06 | 1994-04-05 | Proclosure Inc. | Method and apparatus for simultaneously holding and sealing tissue |
US5334193A (en) * | 1992-11-13 | 1994-08-02 | American Cardiac Ablation Co., Inc. | Fluid cooled ablation catheter |
US5540678A (en) | 1992-12-31 | 1996-07-30 | Laser Centers Of America | Apparatus and method for efficiently transmitting optic energy from a reuseable optic element to a disposable optic element |
US5342358A (en) | 1993-01-12 | 1994-08-30 | S.L.T. Japan Co., Ltd. | Apparatus for operation by laser energy |
US5354294A (en) | 1993-05-26 | 1994-10-11 | Xintec Corporation | Combination reflectance fiber optic laser beam angle delivery |
US5366456A (en) | 1993-02-08 | 1994-11-22 | Xintec Corporation | Angle firing fiber optic laser scalpel and method of use |
US5287380A (en) | 1993-02-19 | 1994-02-15 | Candela Laser Corporation | Method and apparatus for generating long output pulses from flashlamp-excited lasers |
US5356081A (en) | 1993-02-24 | 1994-10-18 | Electric Power Research Institute, Inc. | Apparatus and process for employing synergistic destructive powers of a water stream and a laser beam |
US5527350A (en) | 1993-02-24 | 1996-06-18 | Star Medical Technologies, Inc. | Pulsed infrared laser treatment of psoriasis |
US5368038A (en) | 1993-03-08 | 1994-11-29 | Thermoscan Inc. | Optical system for an infrared thermometer |
DE9303352U1 (en) | 1993-03-08 | 1993-07-22 | Elfo Ag Sachseln, Sachseln, Ch | |
US5387211B1 (en) | 1993-03-10 | 1996-12-31 | Trimedyne Inc | Multi-head laser assembly |
US5304170A (en) * | 1993-03-12 | 1994-04-19 | Green Howard A | Method of laser-induced tissue necrosis in carotenoid-containing skin structures |
US5350376A (en) | 1993-04-16 | 1994-09-27 | Ceramoptec, Inc. | Optical controller device |
GB9309397D0 (en) | 1993-05-07 | 1993-06-23 | Patel Bipin C M | Laser treatment |
US5421339A (en) | 1993-05-12 | 1995-06-06 | Board Of Regents, The University Of Texas System | Diagnosis of dysplasia using laser induced fluoroescence |
US5628771A (en) | 1993-05-12 | 1997-05-13 | Olympus Optical Co., Ltd. | Electromagnetic-wave thermatological device |
US5454807A (en) | 1993-05-14 | 1995-10-03 | Boston Scientific Corporation | Medical treatment of deeply seated tissue using optical radiation |
US5395356A (en) | 1993-06-04 | 1995-03-07 | Summit Technology, Inc. | Correction of presbyopia by photorefractive keratectomy |
US5403306A (en) * | 1993-06-22 | 1995-04-04 | Vanderbilt University | Laser surgery method |
DE4323585A1 (en) | 1993-07-14 | 1995-01-19 | Delma Elektro Med App | Bipolar high-frequency surgical instrument |
US5668824A (en) | 1993-07-28 | 1997-09-16 | Cynosure, Inc. | Method and apparatus for replenishing dye solution in a dye laser |
US5445608A (en) | 1993-08-16 | 1995-08-29 | James C. Chen | Method and apparatus for providing light-activated therapy |
US5368031A (en) | 1993-08-29 | 1994-11-29 | General Electric Company | Magnetic resonance surgery using heat waves produced with a laser fiber |
JP2616668B2 (en) | 1993-08-30 | 1997-06-04 | 日本電気株式会社 | Hermetically sealed structure of optical fiber introduction section |
FR2709763B1 (en) | 1993-09-08 | 1995-10-13 | Commissariat Energie Atomique | Device for processing a material, with miniaturized photo-ion head. |
US5496307A (en) | 1993-09-10 | 1996-03-05 | S.L.T. Japan Co., Ltd. | Laser light irradiation apparatus for medical treatment |
US5420768A (en) | 1993-09-13 | 1995-05-30 | Kennedy; John | Portable led photocuring device |
US6056738A (en) * | 1997-01-31 | 2000-05-02 | Transmedica International, Inc. | Interstitial fluid monitoring |
US6635075B2 (en) | 1993-10-04 | 2003-10-21 | Huan-Chen Li | Method and apparatus for treatment of skin itch and disease |
US6245093B1 (en) | 1993-10-04 | 2001-06-12 | Huan-Chen Li | Method and apparatus for treatment of skin itch and disease |
US5415654A (en) * | 1993-10-05 | 1995-05-16 | S.L.T. Japan Co., Ltd. | Laser balloon catheter apparatus |
IL107248A0 (en) | 1993-10-11 | 1994-01-25 | Amcor Ltd | Apparatus for treatment of the oral cavity |
US5647866A (en) | 1993-11-09 | 1997-07-15 | Zaias; Nardo | Method of hair depilation |
US5498935A (en) | 1993-11-12 | 1996-03-12 | William H. McMahan | Laser flash lamp control system |
US5885211A (en) | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
US5458140A (en) | 1993-11-15 | 1995-10-17 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers |
US5445611A (en) | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
US5394492A (en) | 1993-11-19 | 1995-02-28 | Applied Optronics Corporation | High power semiconductor laser system |
US5413587A (en) * | 1993-11-22 | 1995-05-09 | Hochstein; Peter A. | Infrared heating apparatus and methods |
US20020019624A1 (en) | 1993-12-08 | 2002-02-14 | Clement Robert Marc | Depilation |
GB9325109D0 (en) | 1993-12-08 | 1994-02-09 | Sls Wales Ltd | Depilation |
US5628744A (en) | 1993-12-21 | 1997-05-13 | Laserscope | Treatment beam handpiece |
WO1995017924A1 (en) | 1993-12-30 | 1995-07-06 | The General Hospital Corporation | Apparatus and methods for laser-induced superficial alteration of a substrate |
US5558666A (en) | 1994-01-14 | 1996-09-24 | Coherent, Inc. | Handpiece for producing highly collimated laser beam for dermatological procedures |
US5358503A (en) | 1994-01-25 | 1994-10-25 | Bertwell Dale E | Photo-thermal therapeutic device and method |
AT400305B (en) | 1994-03-07 | 1995-12-27 | Divida Ges M B H Methoden Und | Instrument for the treatment of skin zones |
JPH07249798A (en) | 1994-03-09 | 1995-09-26 | Fujitsu Ltd | Optical device securing apparatus and its manufacture |
US5616140A (en) * | 1994-03-21 | 1997-04-01 | Prescott; Marvin | Method and apparatus for therapeutic laser treatment |
US5505726A (en) * | 1994-03-21 | 1996-04-09 | Dusa Pharmaceuticals, Inc. | Article of manufacture for the photodynamic therapy of dermal lesion |
US5561881A (en) | 1994-03-22 | 1996-10-08 | U.S. Philips Corporation | Electric toothbrush |
JP3530954B2 (en) * | 1994-03-24 | 2004-05-24 | 清之 竹迫 | Far-infrared sterilizer |
US5979454A (en) * | 1995-05-15 | 1999-11-09 | The Regents Of The University Of California | Method and apparatus for causing rapid and deep spatially selective coagulation during thermally mediated therapeutic procedures |
US6248103B1 (en) | 1994-04-05 | 2001-06-19 | The Regents Of The University Of California | Apparatus and method for dynamic cooling of biological tissues for thermal mediated surgery using long laser pulses |
RU2089126C1 (en) | 1994-04-11 | 1997-09-10 | Учебно-научно-производственный "Лазерный центр" Института точной механики и оптики | Method of treatment of tooth hard tissues by laser radiation and device for its realization |
US5464436A (en) | 1994-04-28 | 1995-11-07 | Lasermedics, Inc. | Method of performing laser therapy |
WO1995029737A1 (en) | 1994-05-03 | 1995-11-09 | Board Of Regents, The University Of Texas System | Apparatus and method for noninvasive doppler ultrasound-guided real-time control of tissue damage in thermal therapy |
FR2719470B1 (en) | 1994-05-04 | 1996-06-28 | Oreal | Method for bleaching hair by laser irradiation with cooling, and device for implementing it. |
US5519534A (en) * | 1994-05-25 | 1996-05-21 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Irradiance attachment for an optical fiber to provide a uniform level of illumination across a plane |
JP3596029B2 (en) | 1994-06-06 | 2004-12-02 | 住友電気工業株式会社 | Semiconductor laser module |
US5422112A (en) | 1994-06-09 | 1995-06-06 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Thickened cosmetic compositions |
US5652481A (en) | 1994-06-10 | 1997-07-29 | Beacon Light Products, Inc. | Automatic state tranition controller for a fluorescent lamp |
JPH07328025A (en) | 1994-06-14 | 1995-12-19 | Toshiba Corp | Medical laser device |
US6405732B1 (en) | 1994-06-24 | 2002-06-18 | Curon Medical, Inc. | Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors |
JPH0815539A (en) | 1994-06-30 | 1996-01-19 | Hoya Corp | Optical coupler |
US5586132A (en) | 1994-07-27 | 1996-12-17 | Laser Industries Ltd. | Method and apparatus for generating bright light sources |
US5810802A (en) | 1994-08-08 | 1998-09-22 | E.P. Technologies, Inc. | Systems and methods for controlling tissue ablation using multiple temperature sensing elements |
JPH0866781A (en) | 1994-08-30 | 1996-03-12 | Mitsubishi Electric Corp | Excimer laser beam irradiating device |
US5530711A (en) | 1994-09-01 | 1996-06-25 | The United States Of America As Represented By The Secretary Of The Navy | Low threshold diode-pumped tunable dye laser |
US5502582A (en) | 1994-09-02 | 1996-03-26 | Aavid Laboratories, Inc. | Light source cooler for LCD monitor |
US5531740A (en) | 1994-09-06 | 1996-07-02 | Rapistan Demag Corporation | Automatic color-activated scanning treatment of dermatological conditions by laser |
US5698866A (en) | 1994-09-19 | 1997-12-16 | Pdt Systems, Inc. | Uniform illuminator for phototherapy |
US5531739A (en) | 1994-09-23 | 1996-07-02 | Coherent, Inc. | Method of treating veins |
US5522813A (en) * | 1994-09-23 | 1996-06-04 | Coherent, Inc. | Method of treating veins |
US5669916A (en) | 1994-09-28 | 1997-09-23 | The General Hospital Corporation | Method of hair removal |
US5662643A (en) | 1994-09-28 | 1997-09-02 | Abiomed R & D, Inc. | Laser welding system |
US5608210A (en) | 1994-09-29 | 1997-03-04 | Esparza; Joel | Infrared aided method and apparatus for venous examination |
US5595178A (en) | 1994-10-02 | 1997-01-21 | Hmt High Medical Technologies Gmbh | System, method and apparatus for treatment of degenerative bone |
US5735884A (en) * | 1994-10-04 | 1998-04-07 | Medtronic, Inc. | Filtered feedthrough assembly for implantable medical device |
US5746735A (en) | 1994-10-26 | 1998-05-05 | Cynosure, Inc. | Ultra long pulsed dye laser device for treatment of ectatic vessels and method therefor |
US5571098A (en) | 1994-11-01 | 1996-11-05 | The General Hospital Corporation | Laser surgical devices |
RU2089127C1 (en) | 1994-11-02 | 1997-09-10 | Григорий Борисович Альтшулер | Method of treatment of tooth hard tissues by laser radiation and device for its realization |
US5541948A (en) | 1994-11-28 | 1996-07-30 | The Regents Of The University Of California | Transition-metal doped sulfide, selenide, and telluride laser crystal and lasers |
AT403654B (en) | 1994-12-01 | 1998-04-27 | Binder Michael Dr | DEVICE FOR THE OPTICAL EXAMINATION OF HUMAN SKIN AND THE SAME ASSIGNMENT EVALUATION DEVICE |
WO1996017656A1 (en) | 1994-12-09 | 1996-06-13 | Cynosure, Inc. | Near-infrared selective photothermolysis for vascular targets |
US5558667A (en) | 1994-12-14 | 1996-09-24 | Coherent, Inc. | Method and apparatus for treating vascular lesions |
GB9514872D0 (en) | 1994-12-14 | 1995-09-20 | Brine Lee | Optical fibre laser delivery probe and use thereof |
US5557625A (en) | 1995-01-05 | 1996-09-17 | Cynosure, Inc. | Coupled-cavity resonator to improve the intensity profile of a laser beam |
AT401342B (en) | 1995-01-17 | 1996-08-26 | Myles Handels Gmbh | SOFTLASER WITH INTEGRATED POINT DETECTOR FOR ACUPUNCTURE POINTS |
US5632741A (en) | 1995-01-20 | 1997-05-27 | Lucid Technologies, Inc. | Epilation system |
US5743902A (en) | 1995-01-23 | 1998-04-28 | Coherent, Inc. | Hand-held laser scanner |
US5599342A (en) | 1995-01-27 | 1997-02-04 | Candela Laser Corporation | Method for treating pigmentation abnormalities using pulsed laser radiation with an elongated cross-section and apparatus for providing same |
US5735844A (en) | 1995-02-01 | 1998-04-07 | The General Hospital Corporation | Hair removal using optical pulses |
US5611795A (en) | 1995-02-03 | 1997-03-18 | Laser Industries, Ltd. | Laser facial rejuvenation |
US5643334A (en) | 1995-02-07 | 1997-07-01 | Esc Medical Systems Ltd. | Method and apparatus for the diagnostic and composite pulsed heating and photodynamic therapy treatment |
US5728090A (en) | 1995-02-09 | 1998-03-17 | Quantum Devices, Inc. | Apparatus for irradiating living cells |
US6409722B1 (en) | 1998-07-07 | 2002-06-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
RU2096051C1 (en) | 1995-02-24 | 1997-11-20 | Григорий Борисович Альтшулер | Apparatus for laser treatment of biological tissues (alternative embodiments) |
WO1996028212A1 (en) | 1995-03-09 | 1996-09-19 | Innotech Usa, Inc. | Laser surgical device and method of its use |
US5868731A (en) | 1996-03-04 | 1999-02-09 | Innotech Usa, Inc. | Laser surgical device and method of its use |
US5885273A (en) * | 1995-03-29 | 1999-03-23 | Esc Medical Systems, Ltd. | Method for depilation using pulsed electromagnetic radiation |
CN1090022C (en) | 1995-04-04 | 2002-09-04 | 俄克拉荷马创伤治疗所 | Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant |
RU2082337C1 (en) | 1995-04-10 | 1997-06-27 | Григорий Борисович Альтшулер | Tip piece of laser system for treating biological tissue |
US6135994A (en) | 1995-04-17 | 2000-10-24 | Chernoff; W. Gregory | Surgical method |
US6056548A (en) | 1995-04-26 | 2000-05-02 | Ceramoptec Industries, Inc. | Hygienic dental laser photo treatment method |
US5658148A (en) | 1995-04-26 | 1997-08-19 | Ceramoptec Industries, Inc. | Dental laser brushing or cleaning device |
US5688267A (en) | 1995-05-01 | 1997-11-18 | Ep Technologies, Inc. | Systems and methods for sensing multiple temperature conditions during tissue ablation |
JPH08299310A (en) | 1995-05-02 | 1996-11-19 | Toa Medical Electronics Co Ltd | Non-invasive blood analysis device and method therefor |
US6425912B1 (en) | 1995-05-05 | 2002-07-30 | Thermage, Inc. | Method and apparatus for modifying skin surface and soft tissue structure |
US6430446B1 (en) | 1995-05-05 | 2002-08-06 | Thermage, Inc. | Apparatus for tissue remodeling |
US6241753B1 (en) * | 1995-05-05 | 2001-06-05 | Thermage, Inc. | Method for scar collagen formation and contraction |
US5660836A (en) | 1995-05-05 | 1997-08-26 | Knowlton; Edward W. | Method and apparatus for controlled contraction of collagen tissue |
DE29508077U1 (en) | 1995-05-16 | 1995-08-10 | Wilden Lutz Dr Med | Oral care device |
US5624435A (en) | 1995-06-05 | 1997-04-29 | Cynosure, Inc. | Ultra-long flashlamp-excited pulse dye laser for therapy and method therefor |
US6022346A (en) * | 1995-06-07 | 2000-02-08 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using self-heated electrodes |
DE19521003C1 (en) | 1995-06-08 | 1996-08-14 | Baasel Carl Lasertech | Pulsed light source for removing biological tissue |
JP3507204B2 (en) | 1995-06-29 | 2004-03-15 | キヤノン株式会社 | Ophthalmic equipment |
FR2736390B1 (en) * | 1995-07-05 | 1997-08-08 | Hispano Suiza Sa | PUSH INVERTER OF A SHELL TURBOREACTOR |
US5673451A (en) | 1995-07-06 | 1997-10-07 | Moore; James R. | Instructional toothbrush |
JP3592406B2 (en) | 1995-07-10 | 2004-11-24 | 富士通株式会社 | Optical module and method for manufacturing optical module |
US5658323A (en) * | 1995-07-12 | 1997-08-19 | Miller; Iain D. | Method and apparatus for dermatology treatment |
US5879376A (en) * | 1995-07-12 | 1999-03-09 | Luxar Corporation | Method and apparatus for dermatology treatment |
US6263233B1 (en) | 1995-07-13 | 2001-07-17 | Lucid, Inc. | Handheld imaging microscope |
US6240306B1 (en) | 1995-08-09 | 2001-05-29 | Rio Grande Medical Technologies, Inc. | Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration |
US6669685B1 (en) | 1997-11-06 | 2003-12-30 | Biolase Technology, Inc. | Tissue remover and method |
US7620290B2 (en) | 1995-08-31 | 2009-11-17 | Biolase Technology, Inc. | Modified-output fiber optic tips |
US5849029A (en) | 1995-12-26 | 1998-12-15 | Esc Medical Systems, Ltd. | Method for controlling the thermal profile of the skin |
US5546214A (en) | 1995-09-13 | 1996-08-13 | Reliant Technologies, Inc. | Method and apparatus for treating a surface with a scanning laser beam having an improved intensity cross-section |
US5964749A (en) | 1995-09-15 | 1999-10-12 | Esc Medical Systems Ltd. | Method and apparatus for skin rejuvenation and wrinkle smoothing |
JPH0984803A (en) | 1995-09-27 | 1997-03-31 | Terumo Corp | Laser treatment apparatus |
US5836999A (en) | 1995-09-28 | 1998-11-17 | Esc Medical Systems Ltd. | Method and apparatus for treating psoriasis using pulsed electromagnetic radiation |
US5776175A (en) | 1995-09-29 | 1998-07-07 | Esc Medical Systems Ltd. | Method and apparatus for treatment of cancer using pulsed electromagnetic radiation |
GB9520564D0 (en) | 1995-10-07 | 1995-12-13 | Philips Electronics Nv | Apparatus for treating a patient |
US5824023A (en) | 1995-10-12 | 1998-10-20 | The General Hospital Corporation | Radiation-delivery device |
US5916211A (en) | 1995-11-03 | 1999-06-29 | Quon; Hew W. | Permanent hair removal using visible red wavelength spectrum lasers |
US5921981A (en) | 1995-11-09 | 1999-07-13 | Alcon Laboratories, Inc. | Multi-spot laser surgery |
JPH09141869A (en) | 1995-11-24 | 1997-06-03 | Seiko Epson Corp | Ink-jet type recording apparatus |
US6083217A (en) | 1995-11-29 | 2000-07-04 | Lumedics, Ltd. | Destruction for unwanted tissue by deep laser heating of water |
US5897549A (en) | 1995-11-29 | 1999-04-27 | Lumedics, Ltd. | Transformation of unwanted tissue by deep laser heating of water |
US5837001A (en) | 1995-12-08 | 1998-11-17 | C. R. Bard | Radio frequency energy delivery system for multipolar electrode catheters |
US5713738A (en) | 1995-12-12 | 1998-02-03 | Britesmile, Inc. | Method for whitening teeth |
IL118229A0 (en) | 1996-05-12 | 1997-03-18 | Laser Ind Ltd | Apparatus and method for cutaneous treatment employing a laser |
US5879346A (en) | 1995-12-18 | 1999-03-09 | Esc Medical Systems, Ltd. | Hair removal by selective photothermolysis with an alexandrite laser |
US5651783A (en) | 1995-12-20 | 1997-07-29 | Reynard; Michael | Fiber optic sleeve for surgical instruments |
CA2166034A1 (en) | 1995-12-22 | 1997-06-23 | Chia-Yu Cheng | Skin brush massage method |
KR0155936B1 (en) | 1995-12-26 | 1998-12-15 | 손욱 | Fluorescent lamp ballast circuit |
US7006874B2 (en) | 1996-01-05 | 2006-02-28 | Thermage, Inc. | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory |
GB9602375D0 (en) | 1996-02-06 | 1996-04-03 | Jones Gary L | Laser depilation apparatus and method |
US20070185552A1 (en) | 1996-02-13 | 2007-08-09 | Leonardo Masotti | Device and method for biological tissue stimulation by high intensity laser therapy |
IT1286551B1 (en) | 1996-02-13 | 1998-07-15 | El En S R L | DEVICE AND METHOD FOR THE ELIMINATION OF ADIPOSE LAYERS THROUGH LASER ENERGY |
JPH09218325A (en) | 1996-02-13 | 1997-08-19 | Mitsubishi Electric Corp | Semiconductor laser module |
JPH09220292A (en) | 1996-02-20 | 1997-08-26 | Minolta Co Ltd | Phototherapy equipment |
US5971976A (en) | 1996-02-20 | 1999-10-26 | Computer Motion, Inc. | Motion minimization and compensation system for use in surgical procedures |
US5835648A (en) | 1996-03-07 | 1998-11-10 | Miravant Systems, Inc. | Surface illuminator for photodynamic therapy |
US5818580A (en) | 1996-03-12 | 1998-10-06 | Rutgers, The State University | Simultaneous multisample analysis and apparatus therefor |
US6239442B1 (en) | 1996-03-21 | 2001-05-29 | Keiji Iimura | Cleaning apparatus using ultraviolet rays |
US5630811A (en) | 1996-03-25 | 1997-05-20 | Miller; Iain D. | Method and apparatus for hair removal |
US5843072A (en) | 1996-11-07 | 1998-12-01 | Cynosure, Inc. | Method for treatment of unwanted veins and device therefor |
KR100376650B1 (en) * | 1996-04-09 | 2003-08-25 | 싸이노슈어, 인코포레이티드 | Alexander laser system for the treatment of skin pathological specimens |
US5871479A (en) * | 1996-11-07 | 1999-02-16 | Cynosure, Inc. | Alexandrite laser system for hair removal and method therefor |
WO1997037723A1 (en) | 1996-04-10 | 1997-10-16 | New Star Lasers, Inc. | Improved method and device for laser induced shrinking of collagen |
US5742392A (en) | 1996-04-16 | 1998-04-21 | Seymour Light, Inc. | Polarized material inspection apparatus |
US5944687A (en) | 1996-04-24 | 1999-08-31 | The Regents Of The University Of California | Opto-acoustic transducer for medical applications |
US5893828A (en) | 1996-05-02 | 1999-04-13 | Uram; Martin | Contact laser surgical endoscope and associated myringotomy procedure |
US5662644A (en) | 1996-05-14 | 1997-09-02 | Mdlt, Inc. | Dermatological laser apparatus and method |
TW414035U (en) | 1996-05-14 | 2000-12-01 | Kao Corp | Toothbrush |
US5743901A (en) * | 1996-05-15 | 1998-04-28 | Star Medical Technologies, Inc. | High fluence diode laser device and method for the fabrication and use thereof |
US5655547A (en) * | 1996-05-15 | 1997-08-12 | Esc Medical Systems Ltd. | Method for laser surgery |
US6013053A (en) | 1996-05-17 | 2000-01-11 | Qlt Photo Therapeutics Inc. | Balloon catheter for photodynamic therapy |
GB9611170D0 (en) | 1996-05-29 | 1996-07-31 | Sls Wales Ltd | Reduction of vascular blemishes by selective thermolysis |
GB9611180D0 (en) | 1996-05-29 | 1996-07-31 | Sls Wales Ltd | Treatment of vascular lesions |
US5776129A (en) | 1996-06-12 | 1998-07-07 | Ethicon Endo-Surgery, Inc. | Endometrial ablation apparatus and method |
DE69722414T2 (en) | 1996-07-03 | 2004-05-19 | Altea Therapeutics Corp. | MULTIPLE MECHANICAL MICROPERFORATION OF SKIN OR MUCOSA |
JPH1014661A (en) | 1996-07-09 | 1998-01-20 | Kinue Mogami | Electric toothbrush set |
KR100205052B1 (en) | 1996-07-12 | 1999-06-15 | 정선종 | Mode locking optical fiber laser of wavelength tunable type |
AU3813897A (en) * | 1996-07-25 | 1998-02-20 | Light Medicine, Inc. | Photodynamic therapy apparatus and methods |
US6443974B1 (en) | 1996-07-28 | 2002-09-03 | Biosense, Inc. | Electromagnetic cardiac biostimulation |
US5814008A (en) | 1996-07-29 | 1998-09-29 | Light Sciences Limited Partnership | Method and device for applying hyperthermia to enhance drug perfusion and efficacy of subsequent light therapy |
US5976123A (en) * | 1996-07-30 | 1999-11-02 | Laser Aesthetics, Inc. | Heart stabilization |
US5820626A (en) | 1996-07-30 | 1998-10-13 | Laser Aesthetics, Inc. | Cooling laser handpiece with refillable coolant reservoir |
US5913883A (en) | 1996-08-06 | 1999-06-22 | Alexander; Dane | Therapeutic facial mask |
WO1998005380A1 (en) | 1996-08-06 | 1998-02-12 | Knowlton Edward W | Method for tightening skin |
AU3578497A (en) | 1996-08-08 | 1998-03-06 | Light Sciences Limited Partnership | Method and apparatus to treat gingival and periodontal disease |
US6096029A (en) * | 1997-02-24 | 2000-08-01 | Laser Skin Toner, Inc. | Laser method for subsurface cutaneous treatment |
NO963546D0 (en) | 1996-08-23 | 1996-08-23 | Eric Larsen | Method of permanent hair removal using light |
GB9618051D0 (en) | 1996-08-29 | 1996-10-09 | Sls Wales Ltd | Wrinkle removal |
US5851181A (en) | 1996-08-30 | 1998-12-22 | Esc Medical Systems Ltd. | Apparatus for simultaneously viewing and spectrally analyzing a portion of skin |
US6214034B1 (en) * | 1996-09-04 | 2001-04-10 | Radiancy, Inc. | Method of selective photothermolysis |
US5759200A (en) * | 1996-09-04 | 1998-06-02 | Azar; Zion | Method of selective photothermolysis |
US6364888B1 (en) | 1996-09-09 | 2002-04-02 | Intuitive Surgical, Inc. | Alignment of master and slave in a minimally invasive surgical apparatus |
ES2191786T3 (en) | 1996-09-10 | 2003-09-16 | Grigory Borisovich Altshuler | TOOTHBRUSH. |
US5908418A (en) | 1996-09-13 | 1999-06-01 | Dority; Douglas B. | Hand held coagulating device |
JP3036232U (en) | 1996-09-26 | 1997-04-15 | ヤーマン株式会社 | Optical hair removal device |
US5782249A (en) * | 1996-09-30 | 1998-07-21 | Weber; Paul J. | Laser manicure process |
US6424852B1 (en) | 1996-10-18 | 2002-07-23 | Lucid, Inc. | System for confocal imaging within dermal tissue |
JP3365227B2 (en) | 1996-10-25 | 2003-01-08 | 花王株式会社 | Method and apparatus for measuring optical properties of skin surface condition |
US7036516B1 (en) | 1996-10-30 | 2006-05-02 | Xantech Pharmaceuticals, Inc. | Treatment of pigmented tissues using optical energy |
US5893885A (en) | 1996-11-01 | 1999-04-13 | Cordis Webster, Inc. | Multi-electrode ablation catheter |
US6228075B1 (en) | 1996-11-07 | 2001-05-08 | Cynosure, Inc. | Alexandrite laser system for hair removal |
GB9623627D0 (en) | 1996-11-13 | 1997-01-08 | Meditech International Inc | Method and apparatus for photon therapy |
CN1073607C (en) | 1996-11-20 | 2001-10-24 | 中国科学院近代物理研究所 | Electronic radiation solidifying paint for building material surface |
US20060149343A1 (en) | 1996-12-02 | 2006-07-06 | Palomar Medical Technologies, Inc. | Cooling system for a photocosmetic device |
US8182473B2 (en) | 1999-01-08 | 2012-05-22 | Palomar Medical Technologies | Cooling system for a photocosmetic device |
US7204832B2 (en) | 1996-12-02 | 2007-04-17 | Pálomar Medical Technologies, Inc. | Cooling system for a photo cosmetic device |
US20080294152A1 (en) | 1996-12-02 | 2008-11-27 | Palomar Medical Technologies, Inc. | Cooling System For A Photocosmetic Device |
US6517532B1 (en) | 1997-05-15 | 2003-02-11 | Palomar Medical Technologies, Inc. | Light energy delivery head |
FR2756741B1 (en) | 1996-12-05 | 1999-01-08 | Cird Galderma | USE OF A CHROMOPHORE IN A COMPOSITION INTENDED TO BE APPLIED TO THE SKIN BEFORE LASER TREATMENT |
US6162211A (en) * | 1996-12-05 | 2000-12-19 | Thermolase Corporation | Skin enhancement using laser light |
DE19654108C2 (en) | 1996-12-23 | 2001-10-04 | Massholder Karl F | Cleaning system and method for cleaning a surface |
US5879159A (en) | 1996-12-24 | 1999-03-09 | Ion Laser Technology, Inc. | Portable high power arc lamp system and applications therefor |
US5991697A (en) | 1996-12-31 | 1999-11-23 | The Regents Of The University Of California | Method and apparatus for optical Doppler tomographic imaging of fluid flow velocity in highly scattering media |
US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
DK1314400T3 (en) | 1996-12-31 | 2007-10-15 | Altea Therapeutics Corp | Microporation of tissues for delivery of bioactive agents |
US6063108A (en) | 1997-01-06 | 2000-05-16 | Salansky; Norman | Method and apparatus for localized low energy photon therapy (LEPT) |
US6391283B1 (en) | 1997-01-10 | 2002-05-21 | Ultradent Products, Inc. | Methods and apparatus for activating dental compositions |
US5810801A (en) | 1997-02-05 | 1998-09-22 | Candela Corporation | Method and apparatus for treating wrinkles in skin using radiation |
US5906609A (en) | 1997-02-05 | 1999-05-25 | Sahar Technologies | Method for delivering energy within continuous outline |
US5913833A (en) | 1997-02-07 | 1999-06-22 | Abbott Laboratories | Method and apparatus for obtaining biological fluids |
US6200309B1 (en) | 1997-02-13 | 2001-03-13 | Mcdonnell Douglas Corporation | Photodynamic therapy system and method using a phased array raman laser amplifier |
US5836877A (en) | 1997-02-24 | 1998-11-17 | Lucid Inc | System for facilitating pathological examination of a lesion in tissue |
US5974059A (en) | 1997-03-04 | 1999-10-26 | 3M Innovative Properties Company | Frequency doubled fiber laser |
DE19710676C2 (en) | 1997-03-16 | 1999-06-02 | Aesculap Meditec Gmbh | Arrangement for photoablation |
JP4383545B2 (en) | 1997-03-19 | 2009-12-16 | ルーシド インコーポレーテッド | Cell surgery using confocal microscopy |
US5891063A (en) * | 1997-04-03 | 1999-04-06 | Vigil; Arlene | Skin rejuvinating system |
DE29705934U1 (en) | 1997-04-03 | 1997-06-05 | Kaltenbach & Voigt | Diagnostic and treatment device for teeth |
DE19714475C1 (en) * | 1997-04-08 | 1998-12-17 | Wavelight Laser Technologie Gm | Unit for the removal of glass components from the eye |
FR2762504B1 (en) | 1997-04-29 | 1999-09-10 | Cird Galderma | HAIR REMOVAL PROCESS |
US6317624B1 (en) | 1997-05-05 | 2001-11-13 | The General Hospital Corporation | Apparatus and method for demarcating tumors |
US6235015B1 (en) | 1997-05-14 | 2001-05-22 | Applied Optronics Corporation | Method and apparatus for selective hair depilation using a scanned beam of light at 600 to 1000 nm |
WO1998053646A1 (en) * | 1997-05-22 | 1998-11-26 | Schmidt Gregory W | An illumination device using pulse width modulation of a led |
GB9710562D0 (en) | 1997-05-23 | 1997-07-16 | Medical Laser Technologies Lim | Light delivery |
US6117129A (en) | 1997-05-30 | 2000-09-12 | Nidek Co., Ltd. | Laser treatment apparatus |
DE69812725T2 (en) | 1997-05-30 | 2003-10-09 | Nidek Kk | Laser treatment apparatus |
US6030399A (en) | 1997-06-04 | 2000-02-29 | Spectrx, Inc. | Fluid jet blood sampling device and methods |
US20020018754A1 (en) | 1999-03-15 | 2002-02-14 | Paul Albert Sagel | Shapes for tooth whitening strips |
DE19724299C2 (en) | 1997-06-09 | 2003-03-27 | Sli Lichtsysteme Gmbh | Method and device for the cosmetic treatment of acne vulgaris |
EP0885629A3 (en) | 1997-06-16 | 1999-07-21 | Danish Dermatologic Development A/S | Light pulse generating apparatus and cosmetic and therapeutic phototreatment |
AU8149198A (en) * | 1997-06-17 | 1999-01-04 | Cool Laser Optics, Inc. | Method and apparatus for temperature control of biologic tissue with simultaneous irradiation |
ES2316166T3 (en) | 1997-06-20 | 2009-04-01 | Biolase Technology, Inc. | DENTRIFICO SYSTEM AND DENTAL BRUSH ELECTROMAGNETIC RADIATION ISSUER. |
US5883471A (en) | 1997-06-20 | 1999-03-16 | Polycom, Inc. | Flashlamp pulse shaper and method |
US5885274A (en) * | 1997-06-24 | 1999-03-23 | New Star Lasers, Inc. | Filament lamp for dermatological treatment |
US5968034A (en) | 1997-06-24 | 1999-10-19 | Laser Aesthetics, Inc. | Pulsed filament lamp for dermatological treatment |
US5951543A (en) | 1997-06-30 | 1999-09-14 | Clinicon Corporation | Delivery system and method for surgical laser |
US6142650A (en) | 1997-07-10 | 2000-11-07 | Brown; David C. | Laser flashlight |
US6097741A (en) | 1998-02-17 | 2000-08-01 | Calmar Optcom, Inc. | Passively mode-locked fiber lasers |
US6058937A (en) | 1997-07-18 | 2000-05-09 | Miravant Systems, Inc. | Photodynamic Therapy of highly vascularized tissue |
US5921926A (en) | 1997-07-28 | 1999-07-13 | University Of Central Florida | Three dimensional optical imaging colposcopy |
JP4014255B2 (en) | 1997-07-31 | 2007-11-28 | 有限会社開発顧問室 | Laser irradiation device for skin treatment |
US6273885B1 (en) * | 1997-08-16 | 2001-08-14 | Cooltouch Corporation | Handheld photoepilation device and method |
US6251127B1 (en) | 1997-08-25 | 2001-06-26 | Advanced Photodynamic Technologies, Inc. | Dye treatment solution and photodynamic therapy and method of using same |
US6459919B1 (en) | 1997-08-26 | 2002-10-01 | Color Kinetics, Incorporated | Precision illumination methods and systems |
US6074382A (en) * | 1997-08-29 | 2000-06-13 | Asah Medico A/S | Apparatus for tissue treatment |
US6233584B1 (en) | 1997-09-09 | 2001-05-15 | International Business Machines Corporation | Technique for providing a universal query for multiple different databases |
JP3019207B2 (en) | 1997-09-11 | 2000-03-13 | 川崎重工業株式会社 | Excavation equipment for shield machine |
US5813855A (en) | 1997-09-23 | 1998-09-29 | Crisio, Jr.; Raymond A. | Illuminated toothbrush |
ATE328642T1 (en) | 1997-10-08 | 2006-06-15 | Gen Hospital Corp | PHOTOTHERAPEUTIC SYSTEMS |
US5984915A (en) | 1997-10-08 | 1999-11-16 | Trimedyne, Inc. | Percutaneous laser treatment |
US6071239A (en) | 1997-10-27 | 2000-06-06 | Cribbs; Robert W. | Method and apparatus for lipolytic therapy using ultrasound energy |
DE19841217B4 (en) | 1997-10-27 | 2005-06-16 | Applied Photonics Worldwide, Inc., Reno | Apparatus and method for the spectroscopic analysis of human or animal tissue or body fluids |
US20010048077A1 (en) | 1997-10-27 | 2001-12-06 | Afanassieva Natalia I. | Apparatus and method for spectroscopic analysis of human or animal tissue or body fluids |
WO1999022656A1 (en) | 1997-10-30 | 1999-05-14 | Sonique Surgical Systems, Inc. | Laser-assisted liposuction method and apparatus |
US5968033A (en) * | 1997-11-03 | 1999-10-19 | Fuller Research Corporation | Optical delivery system and method for subsurface tissue irradiation |
DE19751867A1 (en) | 1997-11-22 | 1999-05-27 | Bosch Gmbh Robert | Tilt tendency detection in vehicle |
WO1999027997A1 (en) | 1997-12-01 | 1999-06-10 | Esc Medical Systems Ltd. | Improved depilatory method and device |
US5935124A (en) | 1997-12-02 | 1999-08-10 | Cordis Webster, Inc. | Tip electrode with multiple temperature sensors |
WO1999027863A1 (en) * | 1997-12-04 | 1999-06-10 | Thermolase Corporation | Skin cooling apparatus and method for laser assisted skin treatments |
GB2335603B (en) | 1997-12-05 | 2002-12-04 | Thermolase Corp | Skin enhancement using laser light |
US5949222A (en) | 1997-12-08 | 1999-09-07 | Buono; Robert N. | Self-oscillating switch mode DC to DC conversion with current switching threshold hystersis |
US6229831B1 (en) | 1997-12-08 | 2001-05-08 | Coherent, Inc. | Bright diode-laser light-source |
US6007219A (en) | 1997-12-17 | 1999-12-28 | O'meara; James C. | Laser lighting system |
US6113559A (en) | 1997-12-29 | 2000-09-05 | Klopotek; Peter J. | Method and apparatus for therapeutic treatment of skin with ultrasound |
US6325769B1 (en) | 1998-12-29 | 2001-12-04 | Collapeutics, Llc | Method and apparatus for therapeutic treatment of skin |
IL122840A (en) | 1997-12-31 | 2002-04-21 | Radiancy Inc | Apparatus and methods for removing hair |
AU1934699A (en) | 1998-01-07 | 1999-07-26 | Kim Robin Segal | Diode laser irradiation and electrotherapy system for biological tissue stimulation |
US6221068B1 (en) | 1998-01-15 | 2001-04-24 | Northwestern University | Method for welding tissue |
US6200134B1 (en) | 1998-01-20 | 2001-03-13 | Kerr Corporation | Apparatus and method for curing materials with radiation |
US7048731B2 (en) | 1998-01-23 | 2006-05-23 | Laser Abrasive Technologies, Llc | Methods and apparatus for light induced processing of biological tissues and of dental materials |
RU2175873C2 (en) | 1998-01-23 | 2001-11-20 | Альтшулер Григорий Борисович | Method and device for carrying out light-induced treatment of materials, mainly biological tissues |
US6724958B1 (en) | 1998-01-23 | 2004-04-20 | Science & Engineering Associates, Inc. | Handheld laser system emitting visible non-visible radiation |
CN1058905C (en) | 1998-01-25 | 2000-11-29 | 重庆海扶(Hifu)技术有限公司 | High-intensity focus supersonic tumor scanning therapy system |
EP1051781B1 (en) | 1998-01-29 | 2005-03-23 | Visx Incorporated | Laser delivery system with diffractive optic beam integration |
US6165170A (en) | 1998-01-29 | 2000-12-26 | International Business Machines Corporation | Laser dermablator and dermablation |
DE19803460C1 (en) | 1998-01-30 | 1999-08-12 | Dornier Medizintechnik | Application device for the treatment of biological tissue with laser radiation |
US6074385A (en) | 1998-02-03 | 2000-06-13 | Kiefer Corp. | Hair follicle devitalization by induced heating of magnetically susceptible particles |
US20010016732A1 (en) | 1998-02-03 | 2001-08-23 | James L. Hobart | Dual mode laser delivery system providing controllable depth of tissue ablation and corresponding controllable depth of coagulation |
US6416319B1 (en) | 1998-02-13 | 2002-07-09 | Britesmile, Inc. | Tooth whitening device and method of using same |
JP2908407B1 (en) | 1998-02-13 | 1999-06-21 | 甲府日本電気株式会社 | Multiprocessor device |
US6162055A (en) | 1998-02-13 | 2000-12-19 | Britesmile, Inc. | Light activated tooth whitening composition and method of using same |
US6149644A (en) | 1998-02-17 | 2000-11-21 | Altralight, Inc. | Method and apparatus for epidermal treatment with computer controlled moving focused infrared light |
US6149895A (en) | 1998-02-17 | 2000-11-21 | Kreativ, Inc | Dental bleaching compositions, kits & methods |
IL123437A0 (en) | 1998-02-24 | 1998-09-24 | Shalev Pinchas | Apparatus and method for photothermal destruction of oral bacteria |
US6080146A (en) * | 1998-02-24 | 2000-06-27 | Altshuler; Gregory | Method and apparatus for hair removal |
US6029303A (en) | 1998-03-04 | 2000-02-29 | Dewan; Raman N. | Electronic toothbrush |
US6530915B1 (en) | 1998-03-06 | 2003-03-11 | Spectrx, Inc. | Photothermal structure for biomedical applications, and method therefor |
US6022316A (en) | 1998-03-06 | 2000-02-08 | Spectrx, Inc. | Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications |
ATE375752T1 (en) | 1998-03-06 | 2007-11-15 | Spectrx Inc | INTEGRATED TISSUE PORATION, FLUID COLLECTION AND ANALYSIS DEVICE |
US5920374A (en) | 1998-03-24 | 1999-07-06 | Board Of Trustees Of The University Of Arkansas | Computerized screening device utilizing the Pulfrich effect |
EP0947173A1 (en) | 1998-03-30 | 1999-10-06 | Gabriel Bernaz | Probe for high frequency treatment of the skin |
WO1999051157A1 (en) | 1998-04-07 | 1999-10-14 | The General Hospital Corporation | Apparatus and methods for removing blood vessels |
US6264649B1 (en) | 1998-04-09 | 2001-07-24 | Ian Andrew Whitcroft | Laser treatment cooling head |
US6024095A (en) * | 1998-04-10 | 2000-02-15 | Proteus Therapeutics, Inc. | Corneal heat and stretch method and apparatus |
RU2145247C1 (en) | 1998-04-10 | 2000-02-10 | Жаров Владимир Павлович | Photomatrix therapeutic device for treatment of extended pathologies |
AU754594B2 (en) | 1998-04-24 | 2002-11-21 | Indigo Medical, Incorporated | Energy application system with ancillary information exchange capability, energy applicator, and methods associated therewith |
US6511492B1 (en) * | 1998-05-01 | 2003-01-28 | Microvention, Inc. | Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders |
US6223071B1 (en) | 1998-05-01 | 2001-04-24 | Dusa Pharmaceuticals Inc. | Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light |
US5974616A (en) | 1998-05-26 | 1999-11-02 | Dreyfus; Edward | Sound producing toothbrush |
US6099521A (en) | 1998-05-26 | 2000-08-08 | Shadduck; John H. | Semiconductor contact lens cooling system and technique for light-mediated eye therapies |
US6030378A (en) | 1998-05-26 | 2000-02-29 | Stewart; Bob W. | Method of hair removal by transcutaneous application of laser light |
US6203540B1 (en) | 1998-05-28 | 2001-03-20 | Pearl I, Llc | Ultrasound and laser face-lift and bulbous lysing device |
US6110195A (en) | 1998-06-01 | 2000-08-29 | Altralight, Inc. | Method and apparatus for surgical and dermatological treatment by multi-wavelength laser light |
AU4545899A (en) | 1998-06-03 | 1999-12-20 | Robert O. Wolf | System for whitening teeth surfaces |
US7216055B1 (en) | 1998-06-05 | 2007-05-08 | Crossbow Technology, Inc. | Dynamic attitude measurement method and apparatus |
US6029304A (en) | 1998-06-09 | 2000-02-29 | Colgate-Palmolive Company | Light interactive toothbrush |
US6080147A (en) | 1998-06-10 | 2000-06-27 | Tobinick; Edward L. | Method of employing a flashlamp for removal of hair, veins and capillaries |
US6077294A (en) | 1998-06-11 | 2000-06-20 | Cynosure, Inc. | Method for non-invasive wrinkle removal and skin treatment |
DE19827417B4 (en) | 1998-06-19 | 2004-10-28 | Hahn, Rainer, Dr.Med.Dent. | Material for different modification of the optical properties of different cells |
US6319274B1 (en) | 1998-06-22 | 2001-11-20 | John H. Shadduck | Devices and techniques for light-mediated stimulation of trabecular meshwork in glaucoma therapy |
US6416531B2 (en) | 1998-06-24 | 2002-07-09 | Light Sciences Corporation | Application of light at plural treatment sites within a tumor to increase the efficacy of light therapy |
US6447504B1 (en) | 1998-07-02 | 2002-09-10 | Biosense, Inc. | System for treatment of heart tissue using viability map |
DE69940738D1 (en) | 1998-07-09 | 2009-05-28 | Curelight Medical Ltd | DEVICE AND METHOD FOR EFFICIENT HIGHERGETIC PHOTODYNAMIC THERAPY OF ACNE VULGARIS AND SEBORRHOE |
AU5210699A (en) | 1998-07-13 | 2000-02-01 | Sigma Systems Corporation | Thermal platform and method |
US5941701A (en) | 1998-07-14 | 1999-08-24 | Ceramoptec Ind Inc | Device and method to treat oral disease in felines |
JP2000037400A (en) | 1998-07-23 | 2000-02-08 | Nippon Sekigaisen Kogyo Kk | Front surface cooling method at the time of laser irradiation |
US6112123A (en) | 1998-07-28 | 2000-08-29 | Endonetics, Inc. | Device and method for ablation of tissue |
US6322584B2 (en) | 1998-07-31 | 2001-11-27 | Surx, Inc. | Temperature sensing devices and methods to shrink tissues |
US6236891B1 (en) | 1998-07-31 | 2001-05-22 | Surx, Inc. | Limited heat transfer devices and methods to shrink tissues |
GB9816914D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Gmbh | Novel device |
US6126655A (en) | 1998-08-11 | 2000-10-03 | The General Hospital Corporation | Apparatus and method for selective laser-induced heating of biological tissue |
DE19836649C2 (en) | 1998-08-13 | 2002-12-19 | Zeiss Carl Meditec Ag | Medical handpiece |
US6440155B1 (en) | 1998-08-19 | 2002-08-27 | Tokai University Educational System | Device for heating a biotissue employing a strong light |
US8267982B2 (en) | 1998-08-25 | 2012-09-18 | Advanced Photodynamic Technologies, Inc. | Photodynamic cellular and acellular organism eradication utilizing a photosensitive material and surfactant |
US6101207A (en) | 1998-08-25 | 2000-08-08 | Ilorinne; Toni | Dye laser |
US6525819B1 (en) | 1998-09-02 | 2003-02-25 | Pocketspec Technologies Inc. | Colorimeter for dental applications |
US6282442B1 (en) | 1998-09-11 | 2001-08-28 | Surgical Laser Technologies, Inc. | Multi-fit suction irrigation hand piece |
JP3390755B2 (en) | 1998-09-29 | 2003-03-31 | 科学技術振興事業団 | Wavelength tunable short pulse light generating apparatus and method |
WO2000019926A1 (en) | 1998-10-05 | 2000-04-13 | Scimed Life Systems, Inc. | Large area thermal ablation |
US6595986B2 (en) | 1998-10-15 | 2003-07-22 | Stephen Almeida | Multiple pulse photo-dermatological device |
US6228074B1 (en) | 1998-10-15 | 2001-05-08 | Stephen Almeida | Multiple pulse photo-epilator |
US6059820A (en) * | 1998-10-16 | 2000-05-09 | Paradigm Medical Corporation | Tissue cooling rod for laser surgery |
US6438396B1 (en) | 1998-11-05 | 2002-08-20 | Cytometrics, Inc. | Method and apparatus for providing high contrast imaging |
KR100280821B1 (en) | 1998-11-18 | 2001-03-02 | 정선종 | Tunable Fiber Laser |
WO2000030592A1 (en) | 1998-11-20 | 2000-06-02 | The General Hospital Corporation | Permanent, removable tissue markings |
CZ287832B6 (en) | 1998-11-24 | 2001-02-14 | I.B.C., A. S. | Device for light therapy |
JP2000153003A (en) | 1998-11-24 | 2000-06-06 | Ya Man Ltd | Cooling probe for laser beauty culture instrument |
US6096209A (en) * | 1998-11-25 | 2000-08-01 | Aws Industries, L.L.C. | Three media silver recovery apparatus |
US6570893B1 (en) | 1998-11-25 | 2003-05-27 | Science & Technology Corporation @ Unm | Precisely wavelength-tunable and wavelength-switchable narrow linewidth lasers |
US6283956B1 (en) | 1998-11-30 | 2001-09-04 | David H. McDaniels | Reduction, elimination, or stimulation of hair growth |
US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
US6183500B1 (en) | 1998-12-03 | 2001-02-06 | Sli Lichtsysteme Gmbh | Process and apparatus for the cosmetic treatment of acne vulgaris |
US6106293A (en) | 1998-12-04 | 2000-08-22 | Wiesel; Peter E. | Methods for whitening teeth |
US6402739B1 (en) * | 1998-12-08 | 2002-06-11 | Y-Beam Technologies, Inc. | Energy application with cooling |
US6493608B1 (en) | 1999-04-07 | 2002-12-10 | Intuitive Surgical, Inc. | Aspects of a control system of a minimally invasive surgical apparatus |
US6162215A (en) | 1998-12-23 | 2000-12-19 | Feng; Yuan Feng | Cauterization treatment by infrared rays |
US6164837A (en) | 1998-12-30 | 2000-12-26 | Mcdonnell Douglas Corporation | Integrated microelectromechanical alignment and locking apparatus and method for fiber optic module manufacturing |
US6183773B1 (en) | 1999-01-04 | 2001-02-06 | The General Hospital Corporation | Targeting of sebaceous follicles as a treatment of sebaceous gland disorders |
US6370180B2 (en) | 1999-01-08 | 2002-04-09 | Corning Incorporated | Semiconductor-solid state laser optical waveguide pump |
SE522249C2 (en) | 1999-01-13 | 2004-01-27 | Biolight Patent Holding Ab | Control device for controlling external processing by light |
US6220772B1 (en) | 1999-01-13 | 2001-04-24 | Optiva Corporation | Fluid-dispensing and refilling system for a power toothbrush |
US6402410B1 (en) | 1999-01-13 | 2002-06-11 | Philips Oral Healthcare | Fluid-dispensing and refilling system for a power toothbrush |
US6692517B2 (en) * | 1999-01-15 | 2004-02-17 | Cynosure, Inc. | Optical radiation treatment for enhancement of wound healing |
US6210426B1 (en) | 1999-01-15 | 2001-04-03 | Cynosure Inc | Optical radiation treatment for prevention of surgical scars |
SE515992C2 (en) | 1999-01-20 | 2001-11-05 | Biolight Patent Holding Ab | Light emitting organs for medical treatment are externalized by light |
WO2000043070A1 (en) | 1999-01-25 | 2000-07-27 | Jilin Zhu | The optical quantum medical technology and the instrument thereof |
US6159236A (en) | 1999-01-28 | 2000-12-12 | Advanced Photodynamic Technologies, Inc. | Expandable treatment device for photodynamic therapy and method of using same |
WO2000044294A1 (en) | 1999-01-29 | 2000-08-03 | Welch Allyn, Inc. | Apparatus and method of photo-specific tissue treatment |
US6202242B1 (en) | 1999-01-29 | 2001-03-20 | Zephyr Design, Inc. | Light emitting electric toothbrush |
USD424197S (en) | 1999-02-12 | 2000-05-02 | Thermolase Corporation | Laser handpiece housing |
US6332891B1 (en) | 1999-02-16 | 2001-12-25 | Stryker Corporation | System and method for performing image guided surgery |
JP4310049B2 (en) | 1999-02-19 | 2009-08-05 | ボストン サイエンティフィック リミテッド | Laser lithotripsy device using suction |
US20020090725A1 (en) | 2000-11-17 | 2002-07-11 | Simpson David G. | Electroprocessed collagen |
US6187029B1 (en) | 1999-03-02 | 2001-02-13 | Physician's Technology, Llc | Photo-thermal treatment device |
US6491685B2 (en) | 1999-03-04 | 2002-12-10 | The Regents Of The University Of California | Laser and acoustic lens for lithotripsy |
GB9905173D0 (en) | 1999-03-05 | 1999-04-28 | Sls Biophile Limited | Wrinkle reduction |
JP4102031B2 (en) | 1999-03-09 | 2008-06-18 | サーメイジ インコーポレイテッド | Apparatus and method for treating tissue |
JP3188426B2 (en) | 1999-03-12 | 2001-07-16 | ヤーマン株式会社 | Laser irradiation probe |
US6569155B1 (en) | 1999-03-15 | 2003-05-27 | Altus Medical, Inc. | Radiation delivery module and dermal tissue treatment method |
US6383176B1 (en) | 1999-03-15 | 2002-05-07 | Altus Medical, Inc. | Hair removal device and method |
US7041094B2 (en) | 1999-03-15 | 2006-05-09 | Cutera, Inc. | Tissue treatment device and method |
US6106294A (en) | 1999-03-15 | 2000-08-22 | Daniel; Martin K. | Lighting toothbrush and method of use |
US6235016B1 (en) * | 1999-03-16 | 2001-05-22 | Bob W. Stewart | Method of reducing sebum production by application of pulsed light |
US6312451B1 (en) * | 1999-03-23 | 2001-11-06 | Jackson Streeter | Low level laser therapy apparatus |
DE19914108A1 (en) | 1999-03-23 | 2000-10-05 | Plasmaphotonics Gmbh | Irradiation arrangement, in particular for optical thermolysis |
US6240925B1 (en) | 1999-03-23 | 2001-06-05 | Cynosure, Inc. | Photothermal vascular targeting with bioreductive agents |
US6267779B1 (en) | 1999-03-29 | 2001-07-31 | Medelaser, Llc | Method and apparatus for therapeutic laser treatment |
US6484052B1 (en) | 1999-03-30 | 2002-11-19 | The Regents Of The University Of California | Optically generated ultrasound for enhanced drug delivery |
US6409723B1 (en) | 1999-04-02 | 2002-06-25 | Stuart D. Edwards | Treating body tissue by applying energy and substances |
JP4183916B2 (en) | 1999-04-14 | 2008-11-19 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Hair removal apparatus with controllable laser source |
JP4084903B2 (en) | 1999-04-14 | 2008-04-30 | 株式会社オプトン | Far infrared heating device |
US6709269B1 (en) | 2000-04-14 | 2004-03-23 | Gregory B. Altshuler | Apparatus and method for the processing of solid materials, including hard tissues |
US6162212A (en) | 1999-04-19 | 2000-12-19 | Esc Medical Systems, Ltd. | Optimal procedure for performing a hair removal |
JP2000300684A (en) | 1999-04-20 | 2000-10-31 | Nidek Co Ltd | Laser therapeutic equipment |
CA2369792A1 (en) | 1999-04-27 | 2000-11-02 | The General Hospital Corporation | Phototherapy method for treatment of acne |
US6497701B2 (en) | 1999-04-30 | 2002-12-24 | Visx, Incorporated | Method and system for ablating surfaces with partially overlapping craters having consistent curvature |
US6439888B1 (en) | 1999-05-03 | 2002-08-27 | Pls Liquidating Llc | Optical source and method |
RU2182025C2 (en) | 1999-05-05 | 2002-05-10 | Миржалил Хамитович Усманов | Fire-proofing device |
US20050279949A1 (en) | 1999-05-17 | 2005-12-22 | Applera Corporation | Temperature control for light-emitting diode stabilization |
DE19923427A1 (en) | 1999-05-21 | 2000-11-23 | Lohmann Therapie Syst Lts | Device for improved delivery of active agents to skin, useful e.g. for administering opiates, contains agent that increases local skin temperature or blood flow |
US6606755B1 (en) | 1999-05-24 | 2003-08-19 | American Applied Technology | Electronically timed toothbrush system |
WO2000071045A1 (en) | 1999-05-25 | 2000-11-30 | International Technologies (Lasers), Ltd. | Laser for skin treatment |
US7363071B2 (en) | 1999-05-26 | 2008-04-22 | Endocare, Inc. | Computer guided ablation of tissue using integrated ablative/temperature sensing devices |
US6733492B2 (en) | 1999-05-31 | 2004-05-11 | Nidek Co., Ltd. | Laser treatment apparatus |
EP1057454A3 (en) | 1999-05-31 | 2003-11-12 | Nidek Co., Ltd. | Laser skin treatment apparatus |
CA2310550A1 (en) | 1999-06-04 | 2000-12-04 | Eclipse Surgical Technologies, Inc. | Enhanced surgical device tracking system |
GB9912998D0 (en) | 1999-06-04 | 1999-08-04 | Sls Biophile Limited | Depilation |
US7371408B1 (en) | 1999-06-07 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
US6692456B1 (en) | 1999-06-08 | 2004-02-17 | Altea Therapeutics Corporation | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor |
AU5469900A (en) | 1999-06-09 | 2000-12-28 | Altea Technologies, Inc. | Self-removing energy absorbing structure for thermal tissue ablation |
US6685699B1 (en) | 1999-06-09 | 2004-02-03 | Spectrx, Inc. | Self-removing energy absorbing structure for thermal tissue ablation |
CA2377331A1 (en) | 1999-06-18 | 2000-12-28 | Altea Technologies, Inc. | Light beam generation and focusing device |
JP2001000560A (en) | 1999-06-23 | 2001-01-09 | Ya Man Ltd | Laser beam radiation probe |
US7500956B1 (en) | 1999-06-29 | 2009-03-10 | Wilk Peter J | Apparatus and method for resonant destruction of tumors |
WO2001003050A1 (en) | 1999-07-02 | 2001-01-11 | Hypermed Imaging, Inc. | Imaging apparatus with means for fusing thermal and hyperspectral images |
ATE238619T1 (en) | 1999-07-02 | 2003-05-15 | Asah Medico As | LASER CRYSTAL DEVICE |
US20030216795A1 (en) | 1999-07-07 | 2003-11-20 | Yoram Harth | Apparatus and method for high energy photodynamic therapy of acne vulgaris, seborrhea and other skin disorders |
US20020128695A1 (en) | 1999-07-07 | 2002-09-12 | Yoram Harth | Apparatus and method for high energy photodynamic therapy of acne vulgaris and seborrhea |
US20040122492A1 (en) | 1999-07-07 | 2004-06-24 | Yoram Harth | Phototherapeutic treatment of skin conditions |
US6210425B1 (en) | 1999-07-08 | 2001-04-03 | Light Sciences Corporation | Combined imaging and PDT delivery system |
JP3340090B2 (en) | 1999-07-19 | 2002-10-28 | ヤーマン株式会社 | Laser hair removal probe |
US20040111031A1 (en) | 1999-07-22 | 2004-06-10 | Alfano Robert R. | Spectral polarizing tomographic dermatoscope |
US6451007B1 (en) * | 1999-07-29 | 2002-09-17 | Dale E. Koop | Thermal quenching of tissue |
US6413267B1 (en) | 1999-08-09 | 2002-07-02 | Theralase, Inc. | Therapeutic laser device and method including noninvasive subsurface monitoring and controlling means |
US20030078499A1 (en) | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
US6290713B1 (en) | 1999-08-24 | 2001-09-18 | Thomas A. Russell | Flexible illuminators for phototherapy |
DE19944401A1 (en) | 1999-09-16 | 2001-03-22 | Laser & Med Tech Gmbh | Depth/structure-selective biological tissue treatment method and device e.g. for body hair removal, uses simultaneous application of pressure and irradiation with light |
US6529540B1 (en) | 1999-09-22 | 2003-03-04 | Photonics Research Ontario | Variable output coupling laser |
DE19945416C1 (en) | 1999-09-22 | 2001-04-26 | Siemens Ag | Cooling arrangement for X-ray emitter for computer tomograph enables the X-ray source to be operated over longer periods |
US6331111B1 (en) | 1999-09-24 | 2001-12-18 | Cao Group, Inc. | Curing light system useful for curing light activated composite materials |
GB2356570A (en) | 1999-09-30 | 2001-05-30 | Oe Lys Ltd | Acne treating apparatus based on the emission of light in three different ranges of wavelength |
US6406474B1 (en) | 1999-09-30 | 2002-06-18 | Ceramoptec Ind Inc | Device and method for application of radiation |
US7280866B1 (en) | 1999-10-06 | 2007-10-09 | National Research Council Of Canada | Non-invasive screening of skin diseases by visible/near-infrared spectroscopy |
US6758845B1 (en) | 1999-10-08 | 2004-07-06 | Lumenis Inc. | Automatic firing apparatus and methods for laser skin treatment over large areas |
US6355054B1 (en) | 1999-11-05 | 2002-03-12 | Ceramoptec Industries, Inc. | Laser system for improved transbarrier therapeutic radiation delivery |
US6358242B1 (en) | 1999-11-12 | 2002-03-19 | Ceramoptec Industries, Inc. | Post laser treatment for permanent hair removal |
US6530916B1 (en) | 1999-11-15 | 2003-03-11 | Visx, Incorporated | Uniform large area ablation system and method |
AU780278B2 (en) | 1999-11-16 | 2005-03-10 | Covidien Lp | System and method of treating abnormal tissue in the human esophagus |
DE19954710C1 (en) | 1999-11-17 | 2001-03-15 | Pulsion Medical Sys Ag | Apparatus for treatment of blood vessels especially in eye, comprises laser to deliver structured beam and monitor system to measure concentration of chromophoric agents for system control |
JP2001145520A (en) | 1999-11-19 | 2001-05-29 | Sharion Kk | Far infrared rays mask |
US6527764B1 (en) | 1999-12-02 | 2003-03-04 | Ceramoptec Industries, Inc. | Device and method for laser biomodulation in PDT/surgery |
US6364872B1 (en) | 1999-12-06 | 2002-04-02 | Candela Corporation | Multipulse dye laser |
JP3188437B2 (en) | 1999-12-08 | 2001-07-16 | ヤーマン株式会社 | Laser irradiation probe |
US6638238B1 (en) | 1999-12-09 | 2003-10-28 | The Regents Of The University Of California | Liposuction cannula device and method |
US6743222B2 (en) | 1999-12-10 | 2004-06-01 | Candela Corporation | Method of treating disorders associated with sebaceous follicles |
DE19959508A1 (en) | 1999-12-10 | 2001-06-13 | Schaeffler Waelzlager Ohg | Guide rail for a linear bearing |
US6354370B1 (en) * | 1999-12-16 | 2002-03-12 | The United States Of America As Represented By The Secretary Of The Air Force | Liquid spray phase-change cooling of laser devices |
EP1244390B1 (en) | 1999-12-30 | 2006-08-16 | Pearl Technology Holdings, LLC | Face-lifting device |
CO5271709A1 (en) | 2000-01-12 | 2003-04-30 | Pfizer Prod Inc | COMPOSITIONS AND PROCEDURES FOR THE AND TREATMENT OF AFFECTIONS RESPONDING TO STROGENS |
JP2001196665A (en) | 2000-01-13 | 2001-07-19 | Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai | Two wavelength laser machining optical apparatus and laser machining method |
US6595934B1 (en) | 2000-01-19 | 2003-07-22 | Medtronic Xomed, Inc. | Methods of skin rejuvenation using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
US20020091377A1 (en) | 2000-01-25 | 2002-07-11 | Anderson R. Rox | Method and apparatus for medical treatment utilizing long duration electromagnetic radiation |
US6669688B2 (en) * | 2000-01-25 | 2003-12-30 | The Regents Of The University Of California | Method and apparatus for measuring the heat transfer coefficient during cryogen spray cooling of tissue |
WO2001054580A1 (en) | 2000-01-27 | 2001-08-02 | National Research Council Of Canada | Visible-near infrared spectroscopy in burn injury assessment |
JP2001238968A (en) | 2000-03-01 | 2001-09-04 | Ya Man Ltd | Laser beam irradiation probe |
US6464693B1 (en) | 2000-03-06 | 2002-10-15 | Plc Medical Systems, Inc. | Myocardial revascularization |
US7320593B2 (en) | 2000-03-08 | 2008-01-22 | Tir Systems Ltd. | Light emitting diode light source for curing dental composites |
US6436094B1 (en) | 2000-03-16 | 2002-08-20 | Laserscope, Inc. | Electromagnetic and laser treatment and cooling device |
GB2370992B (en) | 2000-03-23 | 2002-11-20 | Photo Therapeutics Ltd | Therapeutic light source and method |
US6749623B1 (en) | 2000-03-31 | 2004-06-15 | Richard A Hsi | Method and apparatus for catheter phototherapy with dose sensing |
GB2360946B (en) | 2000-04-08 | 2002-06-12 | Lynton Lasers Ltd | Dermatological treatment apparatus |
WO2001078830A2 (en) | 2000-04-17 | 2001-10-25 | Medelaser, Llc | Photostimulaton treatment apparatus and methods for use |
GB2361430A (en) | 2000-04-17 | 2001-10-24 | Photo Therapeutics Ltd | Therapeutic discharge lamps |
EP1278471B1 (en) | 2000-04-27 | 2005-06-15 | Medtronic, Inc. | Vibration sensitive ablation apparatus |
US6554439B1 (en) | 2000-05-15 | 2003-04-29 | The Mclean Hospital | Illumination apparatus for simulating dynamic light conditions |
US6551346B2 (en) | 2000-05-17 | 2003-04-22 | Kent Crossley | Method and apparatus to prevent infections |
JP2001343560A (en) | 2000-05-30 | 2001-12-14 | Kyocera Corp | Optical module |
US6409665B1 (en) | 2000-06-01 | 2002-06-25 | Corey D. Scott | Apparatus for applying impedence matching fluid for ultrasonic imaging |
US6652459B2 (en) | 2000-06-28 | 2003-11-25 | Peter Alfred Payne | Ophthalmic uses of lasers |
JP2002011106A (en) | 2000-06-28 | 2002-01-15 | Nidek Co Ltd | Laser therapeutic apparatus |
US6544257B2 (en) | 2000-07-03 | 2003-04-08 | Olympus Optical Co., Ltd. | Thermal treatment apparatus |
GB2364376A (en) | 2000-07-05 | 2002-01-23 | Astron Clinica Ltd | Skin illumination and examination apparatus |
DE10033256A1 (en) | 2000-07-10 | 2002-01-24 | Coronet Werke Gmbh | Method and device for producing bristle goods and bristle goods |
US6471716B1 (en) | 2000-07-11 | 2002-10-29 | Joseph P. Pecukonis | Low level light therapy method and apparatus with improved wavelength, temperature and voltage control |
JP3868724B2 (en) * | 2000-07-18 | 2007-01-17 | 独立行政法人科学技術振興機構 | Ultrasound angioscope system |
EP1341464A4 (en) * | 2000-07-21 | 2009-07-22 | Ceramoptec Gmbh | Treatment for epithelial diseases |
US6454790B1 (en) | 2000-07-21 | 2002-09-24 | Ceramoptec Industries, Inc. | Treatment for Barrett's syndrome |
WO2002009813A1 (en) | 2000-07-31 | 2002-02-07 | El. En. S.P.A. | Method and device for epilation by ultrasound |
US6905492B2 (en) | 2000-07-31 | 2005-06-14 | Galil Medical Ltd. | Planning and facilitation systems and methods for cryosurgery |
IT1316597B1 (en) * | 2000-08-02 | 2003-04-24 | Actis S R L | OPTOACOUSTIC ULTRASONIC GENERATOR FROM LASER ENERGY POWERED THROUGH OPTICAL FIBER. |
US8565860B2 (en) | 2000-08-21 | 2013-10-22 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system |
DE20014735U1 (en) | 2000-08-25 | 2000-10-12 | B & P Ag Roschacherberg | Light therapy device |
US6602275B1 (en) | 2000-09-18 | 2003-08-05 | Jana Sullivan | Device and method for therapeutic treatment of living organisms |
US6702808B1 (en) | 2000-09-28 | 2004-03-09 | Syneron Medical Ltd. | Device and method for treating skin |
US6471712B2 (en) | 2000-10-05 | 2002-10-29 | Steven A. Burres | Dermabrasion and skin care apparatus |
US6435873B1 (en) | 2000-10-10 | 2002-08-20 | 3M Innovative Properties Company | Medication delivery devices |
GB2368020A (en) | 2000-10-18 | 2002-04-24 | Icn Photonics Ltd | Treatment of acne vulgaris skin condition by irradiation with light of specific wavelengths to target specific chromophores & stimulate collagen production |
DE10052296C1 (en) | 2000-10-20 | 2002-04-04 | Braun Gmbh | Electrically-operated hair removal device has pulsed stroboscopic light signal provided by illumination device for illumination of relatively moving working elements |
JP2002200181A (en) * | 2000-10-31 | 2002-07-16 | Shigehiro Kubota | Laser treatment instrument |
US6506053B2 (en) | 2000-11-13 | 2003-01-14 | Peter E. Wiesel | Systems for treating teeth |
US6616447B1 (en) | 2000-11-15 | 2003-09-09 | Biolase Technology, Inc. | Device for dental care and whitening |
US20020071287A1 (en) | 2000-12-13 | 2002-06-13 | 3M Innovative Properties Company | Laser pointer with multiple color beams |
US6808532B2 (en) | 2000-12-15 | 2004-10-26 | Dan E. Andersen | Laser treatment for reducing wrinkles |
US6746444B2 (en) | 2000-12-18 | 2004-06-08 | Douglas J. Key | Method of amplifying a beneficial selective skin response to light energy |
US20080306471A1 (en) | 2000-12-28 | 2008-12-11 | Palomar Medical Technologies, Inc. | Methods and devices for fractional ablation of tissue |
WO2002089750A2 (en) | 2001-01-19 | 2002-11-14 | Advanced Photodynamic Technologies, Inc. | Apparatus and method of photodynamic eradication of organisms utilizing pyrrolnitrin |
CA2444891A1 (en) | 2001-01-22 | 2002-08-15 | Eric Larsen | Photodynamic stimulation device and methods |
ITMO20010008A1 (en) | 2001-01-29 | 2002-07-29 | Laserwave Srl | DEVICE FOR SKIN TREATMENTS |
JP2004518485A (en) | 2001-02-12 | 2004-06-24 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Sonic toothbrush with multiple containers |
US6673095B2 (en) | 2001-02-12 | 2004-01-06 | Wound Healing Of Oklahoma, Inc. | Apparatus and method for delivery of laser light |
US20020110328A1 (en) | 2001-02-14 | 2002-08-15 | Bischel William K. | Multi-channel laser pump source for optical amplifiers |
US8106038B2 (en) | 2001-02-15 | 2012-01-31 | Qlt Inc. | Method for reducing or preventing PDT related inflammation |
JP4034941B2 (en) | 2001-02-28 | 2008-01-16 | 株式会社ニデック | Laser therapy device |
US20020149326A1 (en) | 2001-03-01 | 2002-10-17 | Mikhail Inochkin | Flashlamp drive circuit |
US6888319B2 (en) | 2001-03-01 | 2005-05-03 | Palomar Medical Technologies, Inc. | Flashlamp drive circuit |
US20020127224A1 (en) | 2001-03-02 | 2002-09-12 | James Chen | Use of photoluminescent nanoparticles for photodynamic therapy |
US6497719B2 (en) | 2001-03-06 | 2002-12-24 | Henry Pearl | Apparatus and method for stimulating hair growth |
DE10112289A1 (en) | 2001-03-08 | 2002-09-26 | Optomed Optomedical Systems Gmbh | Irradiating device used for treating acne comprises a radiation source emitting a broad band spectrum in a specified region and operating in the pulse manner |
DE10123926A1 (en) | 2001-03-08 | 2002-09-19 | Optomed Optomedical Systems Gmbh | irradiation device |
JP2002272861A (en) | 2001-03-16 | 2002-09-24 | Terabyt:Kk | Light energy athletes' foot medical treatment machine |
GB0107853D0 (en) | 2001-03-29 | 2001-05-23 | Asclepion Meditec Ltd | Hand apparatus for light delivery |
JP4141260B2 (en) | 2001-03-30 | 2008-08-27 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Skin treatment device with protected radiation output opening |
US20020173777A1 (en) | 2001-03-30 | 2002-11-21 | Sand Bruce J. | Treatment of collagen |
US6697408B2 (en) | 2001-04-04 | 2004-02-24 | Coherent, Inc. | Q-switched cavity dumped CO2 laser for material processing |
US7033348B2 (en) | 2001-04-10 | 2006-04-25 | The Research Foundation Of The City University Of New York | Gelatin based on Power-gel™ as solders for Cr4+laser tissue welding and sealing of lung air leak and fistulas in organs |
US7107996B2 (en) | 2001-04-10 | 2006-09-19 | Ganz Robert A | Apparatus and method for treating atherosclerotic vascular disease through light sterilization |
US6635052B2 (en) | 2001-04-11 | 2003-10-21 | Trimedyne, Inc. | Multi-fiber laser device for shrinking tissue |
US6733490B1 (en) | 2001-04-12 | 2004-05-11 | Iridex Corporation | Method and apparatus for controlling sub-clinical laser procedures with intra-operative monitoring of electrophysiological changes |
ATE308363T1 (en) | 2001-04-18 | 2005-11-15 | Susann Edel | RADIATION DEVICE PARTICULARLY FOR PHOTODYNAMIC DIAGNOSIS OR THERAPY |
DE10120787A1 (en) | 2001-04-25 | 2003-01-09 | Foerderung Von Medizin Bio Und | Remission-controlled device with laser handpiece for sensor-controlled selective laser therapy of blood vessels and skin tissues has multiple-sensor system e.g. using near infrared or visible radiation |
US6755647B2 (en) | 2001-04-26 | 2004-06-29 | New Photonics, Llc | Photocuring device with axial array of light emitting diodes and method of curing |
AU2002305313A1 (en) | 2001-04-30 | 2002-11-11 | Medtronic, Inc. | Implantable medical device and patch system |
US8840918B2 (en) | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
JP4046612B2 (en) | 2001-05-04 | 2008-02-13 | ニトン・コーポレーション | X-ray fluorescence analyzer combined with laser-induced fluorescence quantum analyzer |
US6572634B2 (en) | 2001-05-07 | 2003-06-03 | Myung H. Koo | Nose end adjusting device |
GB0111271D0 (en) | 2001-05-09 | 2001-06-27 | Asclepion Meditec Ltd | A method of stimulating collagen formation |
IL158982A0 (en) | 2001-05-23 | 2004-05-12 | Palomar Medical Tech Inc | Cooling system for a photocosmetic device |
DE10125772C2 (en) | 2001-05-26 | 2003-06-18 | Duerr Dental Gmbh Co Kg | Dental or endoscopic camera |
US6770069B1 (en) | 2001-06-22 | 2004-08-03 | Sciton, Inc. | Laser applicator |
US7150710B2 (en) | 2001-06-26 | 2006-12-19 | Photomed Technologies, Inc. | Therapeutic methods using electromagnetic radiation |
DE10130278B4 (en) | 2001-06-26 | 2005-11-03 | Carl Zeiss Meditec Ag | Method and device for representing an operating area during laser operations |
WO2003003903A2 (en) | 2001-07-02 | 2003-01-16 | Palomar Medical Technologies, Inc. | Laser device for medical/cosmetic procedures |
ITPD20010187A1 (en) | 2001-07-23 | 2003-01-23 | Cutech Srl | POLYPHERIC FOLLICLE TREATMENT, IN PARTICULAR AGAINST HAIR LOSS |
US6607525B2 (en) | 2001-08-01 | 2003-08-19 | Nicolas Franco | Apparatus and method for treating urinary stress incontinence |
US6939344B2 (en) * | 2001-08-02 | 2005-09-06 | Syneron Medical Ltd. | Method for controlling skin temperature during thermal treatment |
US7018396B2 (en) | 2001-08-07 | 2006-03-28 | New England Medical Center Hospitals, Inc. | Method of treating acne |
US20030032900A1 (en) | 2001-08-08 | 2003-02-13 | Engii (2001) Ltd. | System and method for facial treatment |
JP2003052843A (en) | 2001-08-08 | 2003-02-25 | Terabyt:Kk | Wrinkle removing laser treatment device |
US20040260210A1 (en) | 2003-06-23 | 2004-12-23 | Engii (2001) Ltd. | System and method for face and body treatment |
JP2005500108A (en) | 2001-08-15 | 2005-01-06 | リライアント テクノロジーズ,インコーポレイティド | Apparatus and method for thermal excision of biological tissue |
US7094252B2 (en) | 2001-08-21 | 2006-08-22 | Cooltouch Incorporated | Enhanced noninvasive collagen remodeling |
US7384419B2 (en) | 2002-08-26 | 2008-06-10 | Biolase Technology, Inc. | Tapered fused waveguide for delivering treatment electromagnetic radiation toward a target surfaced |
US6942658B1 (en) | 2001-08-24 | 2005-09-13 | Boilase Technology, Inc. | Radiation emitting apparatus with spatially controllable output energy distributions |
US6561808B2 (en) | 2001-09-27 | 2003-05-13 | Ceramoptec Industries, Inc. | Method and tools for oral hygiene |
WO2003026476A2 (en) | 2001-09-27 | 2003-04-03 | Galil Medical Ltd. | Apparatus and method for cryosurgical treatment of tumors of the breast |
US6629989B2 (en) | 2001-10-18 | 2003-10-07 | Shimadzu Corporation | Phototherapy device for pressure pain point therapy and trigger point therapy |
US7144248B2 (en) | 2001-10-18 | 2006-12-05 | Irwin Dean S | Device for oral UV photo-therapy |
US6952856B2 (en) | 2001-11-06 | 2005-10-11 | Create Co., Ltd. | Ionic toothbrush |
US7354448B2 (en) | 2001-11-29 | 2008-04-08 | Palomar Medical Technologies, Inc. | Dental phototherapy methods and compositions |
US20040147984A1 (en) | 2001-11-29 | 2004-07-29 | Palomar Medical Technologies, Inc. | Methods and apparatus for delivering low power optical treatments |
US6648904B2 (en) | 2001-11-29 | 2003-11-18 | Palomar Medical Technologies, Inc. | Method and apparatus for controlling the temperature of a surface |
US6623272B2 (en) | 2001-11-30 | 2003-09-23 | Kathleen Clemans | Light-emitting toothbrush and method of whitening teeth |
EP1627662B1 (en) | 2004-06-10 | 2011-03-02 | Candela Corporation | Apparatus for vacuum-assisted light-based treatments of the skin |
US20040082940A1 (en) | 2002-10-22 | 2004-04-29 | Michael Black | Dermatological apparatus and method |
US20030109860A1 (en) | 2001-12-12 | 2003-06-12 | Michael Black | Multiple laser treatment |
US20030109787A1 (en) | 2001-12-12 | 2003-06-12 | Michael Black | Multiple laser diagnostics |
US20030216719A1 (en) | 2001-12-12 | 2003-11-20 | Len Debenedictis | Method and apparatus for treating skin using patterns of optical energy |
MXPA04005792A (en) | 2001-12-14 | 2005-03-31 | Monteris Medical Inc | Hyperthermia treatment and probe therefor. |
US6692252B2 (en) | 2001-12-17 | 2004-02-17 | Ultradent Products, Inc. | Heat sink with geometric arrangement of LED surfaces |
JP2003192809A (en) | 2001-12-28 | 2003-07-09 | Mitsubishi Paper Mills Ltd | Heat resistant insulation sheet |
US6863781B2 (en) * | 2002-02-26 | 2005-03-08 | Massachusetts Institute Of Technology | Process for photocatalysis and two-electron mixed-valence complexes |
US7086861B2 (en) | 2002-03-01 | 2006-08-08 | Pitz Richard J | System for dispensing viscous materials |
EP1340486A1 (en) | 2002-03-01 | 2003-09-03 | Cognis France S.A. | Use of sugar esters |
US7081128B2 (en) | 2002-03-04 | 2006-07-25 | Hart Barry M | Phototherapy device and method of use |
US6927857B2 (en) | 2002-03-09 | 2005-08-09 | Kimberly-Clark Worldwide, Inc. | Process for the detection of marked components of a composite article using infrared blockers |
EP1482848A4 (en) | 2002-03-12 | 2007-08-15 | Palomar Medical Tech Inc | Method and apparatus for hair growth management |
US8840608B2 (en) | 2002-03-15 | 2014-09-23 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
US20030187319A1 (en) | 2002-03-29 | 2003-10-02 | Olympus Optical Co., Ltd. | Sentinel lymph node detecting apparatus, and method thereof |
US6955684B2 (en) | 2002-03-29 | 2005-10-18 | Savage Jr Henry C | Portable light delivery apparatus and methods |
US7336989B2 (en) | 2002-04-03 | 2008-02-26 | The Regents Of The University Of California | System and method for quantitative or qualitative measurement of exogenous substances in tissue and other materials using laser-induced fluorescence spectroscopy |
AU2003226326A1 (en) | 2002-04-09 | 2003-10-27 | Altshuler, Gregory | Method and apparatus for processing hard material |
AU2003223613A1 (en) | 2002-04-16 | 2003-11-03 | Lumerx, Inc | Chemiluminescent light source using visible light for biotherapy |
US6917715B2 (en) | 2002-04-19 | 2005-07-12 | International Business Machines Corporation | Foveal priority in stereoscopic remote viewing system |
US20060293727A1 (en) | 2002-05-09 | 2006-12-28 | Greg Spooner | System and method for treating exposed tissue with light emitting diodes |
GB2390021A (en) | 2002-05-17 | 2003-12-31 | Ian Charlesworth | Hand-held led apparatus for treating acne |
US20070213698A1 (en) | 2006-03-10 | 2007-09-13 | Palomar Medical Technologies, Inc. | Photocosmetic device |
US7479137B2 (en) | 2002-05-31 | 2009-01-20 | Ya-Man Ltd. | Laser depilator |
DE10225749C5 (en) | 2002-06-10 | 2009-09-10 | Elexxion Gmbh | Medical equipment for treatments in the dental field by means of a laser |
US20030233138A1 (en) | 2002-06-12 | 2003-12-18 | Altus Medical, Inc. | Concentration of divergent light from light emitting diodes into therapeutic light energy |
US7001413B2 (en) | 2002-07-03 | 2006-02-21 | Life Support Technologies, Inc. | Methods and apparatus for light therapy |
US7201766B2 (en) | 2002-07-03 | 2007-04-10 | Life Support Technologies, Inc. | Methods and apparatus for light therapy |
US7282723B2 (en) | 2002-07-09 | 2007-10-16 | Medispectra, Inc. | Methods and apparatus for processing spectral data for use in tissue characterization |
FR2842088B1 (en) | 2002-07-10 | 2004-12-10 | Seb Sa | ELECTRIC KETTLE |
KR101047246B1 (en) | 2002-07-25 | 2011-07-06 | 조나단 에스. 담 | Method and apparatus for using curing LED |
US6902397B2 (en) | 2002-08-01 | 2005-06-07 | Sunstar Americas, Inc. | Enhanced dental hygiene system with direct UVA photoexcitation |
US6780177B2 (en) | 2002-08-27 | 2004-08-24 | Board Of Trustees Of The University Of Arkansas | Conductive interstitial thermal therapy device |
US6860896B2 (en) | 2002-09-03 | 2005-03-01 | Jeffrey T. Samson | Therapeutic method and apparatus |
WO2004026099A2 (en) | 2002-09-20 | 2004-04-01 | Iridex Corporation | Apparatus for real time measure/control of intra-operative effects during laser thermal treatments using light scattering |
US20070219604A1 (en) | 2006-03-20 | 2007-09-20 | Palomar Medical Technologies, Inc. | Treatment of tissue with radiant energy |
US20070213792A1 (en) | 2002-10-07 | 2007-09-13 | Palomar Medical Technologies, Inc. | Treatment Of Tissue Volume With Radiant Energy |
EP2522294A2 (en) | 2002-10-23 | 2012-11-14 | Palomar Medical Technologies, Inc. | Phototreatment device for use with coolants and topical substances |
US7524316B2 (en) | 2002-10-31 | 2009-04-28 | Cooltouch, Inc. | Endovenous closure of varicose veins with mid infrared laser |
US7699058B1 (en) | 2002-11-08 | 2010-04-20 | Jay Harvey H | Hair treatment method |
US7931028B2 (en) | 2003-08-26 | 2011-04-26 | Jay Harvey H | Skin injury or damage prevention method using optical radiation |
US6824542B2 (en) * | 2002-11-08 | 2004-11-30 | Harvey H. Jay | Temporary hair removal method |
US6916316B2 (en) | 2002-11-08 | 2005-07-12 | Harvey H. Jay | Hair treatment method |
WO2004043543A1 (en) | 2002-11-12 | 2004-05-27 | Palomar Medical Technologies, Inc. | Apparatus for performing optical dermatology |
US7377917B2 (en) | 2002-12-09 | 2008-05-27 | The Trustees Of Dartmouth College | Feedback control of thermokeratoplasty treatments |
US6866678B2 (en) | 2002-12-10 | 2005-03-15 | Interbational Technology Center | Phototherapeutic treatment methods and apparatus |
AU2003301111A1 (en) | 2002-12-20 | 2004-07-22 | Palomar Medical Technologies, Inc. | Apparatus for light treatment of acne and other disorders of follicles |
IL154101A0 (en) | 2003-01-23 | 2003-07-31 | Univ Ramot | Minimally invasive controlled surgical system with feedback |
GB2397528B (en) | 2003-01-24 | 2005-07-13 | Enfis Ltd | Method and device for treatment of skin conditions |
US20040143920A1 (en) | 2003-01-24 | 2004-07-29 | Dr. Fresh, Inc. | Illuminated flashing toothbrush and method of use |
US7704247B2 (en) | 2003-02-13 | 2010-04-27 | Barbara Ann Soltz | Dual fiber-optic surgical apparatus |
US20040161213A1 (en) | 2003-02-15 | 2004-08-19 | Tsung-Ting Lee | Fiber optic display device |
AU2004213047A1 (en) | 2003-02-19 | 2004-09-02 | Palomar Medical Technologies, Inc. | Method and apparatus for treating pseudofolliculitis barbae |
EP1596745B1 (en) | 2003-02-25 | 2016-02-17 | Tria Beauty, Inc. | Self-contained, diode-laser-based dermatologic treatment apparatus |
US7413567B2 (en) | 2003-02-25 | 2008-08-19 | Spectragenics, Inc. | Optical sensor and method for identifying the presence of skin |
US20040176764A1 (en) | 2003-03-03 | 2004-09-09 | Centerpulse Spine-Tech, Inc. | Apparatus and method for spinal distraction using a flip-up portal |
US7104985B2 (en) | 2003-03-06 | 2006-09-12 | Martinelli Michael A | Apparatus and method for causing selective necrosis of abnormal cells |
JP4435149B2 (en) | 2003-03-06 | 2010-03-17 | トリア ビューティ インコーポレイテッド | Skin contact sensing device |
US7006223B2 (en) | 2003-03-07 | 2006-02-28 | 3Gen, Llc. | Dermoscopy epiluminescence device employing cross and parallel polarization |
CN1668225A (en) | 2003-03-13 | 2005-09-14 | 雷蒂安西公司 | Electric shaver with vibrating head |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
ES2546658T3 (en) | 2003-03-27 | 2015-09-25 | The General Hospital Corporation | Method for cosmetic dermatological treatment and fractional skin renewal |
US20040199151A1 (en) | 2003-04-03 | 2004-10-07 | Ceramoptec Industries, Inc. | Power regulated medical underskin irradiation treament system |
US20050116673A1 (en) | 2003-04-18 | 2005-06-02 | Rensselaer Polytechnic Institute | Methods and systems for controlling the operation of a tool |
US7144247B2 (en) | 2003-04-25 | 2006-12-05 | Oralum, Llc | Hygienic treatments of structures in body cavities |
US6953341B2 (en) | 2003-08-20 | 2005-10-11 | Oralum, Llc | Toothpick for light treatment of body structures |
US20040234460A1 (en) | 2003-05-21 | 2004-11-25 | Tarver Jeanna Gail | Tooth whitening compositions and methods for using the same |
JP3896097B2 (en) | 2003-06-27 | 2007-03-22 | 日本オプネクスト株式会社 | Receptacle type optical module |
JP2005027702A (en) | 2003-07-07 | 2005-02-03 | Ya Man Ltd | Face treatment mask |
JP2007531544A (en) | 2003-07-11 | 2007-11-08 | リライアント・テクノロジーズ・インコーポレイテッド | Method and apparatus for fractionated light treatment of skin |
US7291140B2 (en) | 2003-07-18 | 2007-11-06 | Cutera, Inc. | System and method for low average power dermatologic light treatment device |
US7145108B2 (en) | 2003-07-22 | 2006-12-05 | Kaz, Incorporated | Configurable heating pad controller |
US8623002B2 (en) | 2003-07-29 | 2014-01-07 | Koninklijke Philips N.V. | Electromagnetic radiation delivery apparatus |
US7208007B2 (en) | 2003-08-07 | 2007-04-24 | Cutera, Inc. | System and method utilizing guided fluorescence for high intensity applications |
US20050065502A1 (en) | 2003-08-11 | 2005-03-24 | Richard Stoltz | Enabling or blocking the emission of an ablation beam based on color of target |
US8083784B2 (en) | 2003-08-19 | 2011-12-27 | Photonx Health Corporation | Photon therapy method and apparatus |
US8870856B2 (en) | 2003-08-25 | 2014-10-28 | Cutera, Inc. | Method for heating skin using light to provide tissue treatment |
US7722600B2 (en) | 2003-08-25 | 2010-05-25 | Cutera, Inc. | System and method for heating skin using light to provide tissue treatment |
US20050049467A1 (en) | 2003-08-28 | 2005-03-03 | Georgios Stamatas | Method for assessing pigmented skin |
US7356053B2 (en) | 2003-10-06 | 2008-04-08 | Continuum Electro-Optics, Inc. | Mode-locked laser with variable pulse duration |
US20050102213A1 (en) | 2003-11-07 | 2005-05-12 | Serkan Savasoglu | Systems and methods for accreting remarketable convertible securities |
US20050113890A1 (en) | 2003-11-25 | 2005-05-26 | Ritchie Paul G. | Energy delivery device with self-heat calibration |
US7118564B2 (en) | 2003-11-26 | 2006-10-10 | Ethicon Endo-Surgery, Inc. | Medical treatment system with energy delivery device for limiting reuse |
ITBO20030717A1 (en) | 2003-11-27 | 2005-05-28 | Espansione Marketing S P A | LIGHT IRRADIATION UNIT. |
US7282060B2 (en) | 2003-12-23 | 2007-10-16 | Reliant Technologies, Inc. | Method and apparatus for monitoring and controlling laser-induced tissue treatment |
US7766903B2 (en) | 2003-12-24 | 2010-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Patterned laser treatment of the retina |
US7090670B2 (en) | 2003-12-31 | 2006-08-15 | Reliant Technologies, Inc. | Multi-spot laser surgical apparatus and method |
WO2005065565A1 (en) | 2003-12-31 | 2005-07-21 | Palomar Medical Technologies, Inc. | Dermatological treatment with vusualization |
US7041100B2 (en) | 2004-01-21 | 2006-05-09 | Syneron Medical Ltd. | Method and system for selective electro-thermolysis of skin targets |
US20050165315A1 (en) | 2004-01-27 | 2005-07-28 | Infraredx, Inc. | Side firing fiber optic array probe |
US7914523B2 (en) | 2004-02-06 | 2011-03-29 | Clinique Dr Daniel Barolet Inc. | Method for the treatment of mammalian tissues |
US7344494B2 (en) | 2004-02-09 | 2008-03-18 | Karl Storz Development Corp. | Endoscope with variable direction of view module |
DE102004008681A1 (en) | 2004-02-21 | 2005-09-08 | Eads Space Transportation Gmbh | Method for energy transmission by means of coherent electromagnetic radiation |
US6893259B1 (en) | 2004-03-08 | 2005-05-17 | Igor Reizenson | Oral hygiene device and method of use therefor |
US20050203497A1 (en) | 2004-03-12 | 2005-09-15 | Trevor Speeg | Medical apparatus and method useful for positioning energy delivery device |
US20050203496A1 (en) | 2004-03-12 | 2005-09-15 | Ritchie Paul G. | Medical apparatus and method useful for thermal treatment of a lumen |
WO2005092438A1 (en) | 2004-03-26 | 2005-10-06 | Ya-Man Ltd. | Treatment device |
JP4504718B2 (en) | 2004-03-31 | 2010-07-14 | テルモ株式会社 | Heat treatment device |
JP4971133B2 (en) | 2004-04-01 | 2012-07-11 | ザ ジェネラル ホスピタル コーポレイション | Equipment for dermatological treatment |
US20090069741A1 (en) | 2004-04-09 | 2009-03-12 | Palomar Medical Technologies, Inc. | Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery |
US20080132886A1 (en) | 2004-04-09 | 2008-06-05 | Palomar Medical Technologies, Inc. | Use of fractional emr technology on incisions and internal tissues |
US20070208252A1 (en) | 2004-04-21 | 2007-09-06 | Acclarent, Inc. | Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses |
AT500141B1 (en) | 2004-04-28 | 2008-03-15 | W & H Dentalwerk Buermoos Gmbh | DENTAL LASER TREATMENT DEVICE |
US20050251116A1 (en) | 2004-05-05 | 2005-11-10 | Minnow Medical, Llc | Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter |
US7842029B2 (en) | 2004-05-07 | 2010-11-30 | Aesthera | Apparatus and method having a cooling material and reduced pressure to treat biological external tissue |
US20050251117A1 (en) | 2004-05-07 | 2005-11-10 | Anderson Robert S | Apparatus and method for treating biological external tissue |
JP2007536963A (en) | 2004-05-13 | 2007-12-20 | ビジャカンパ,フランシスコ ハビエル アルクサ | Medical surgical handpiece |
US7537735B2 (en) | 2004-05-21 | 2009-05-26 | Biomerieux, Inc. | Aspirator systems having an aspirator tip optical level detector and methods for using the same |
US7529019B2 (en) | 2004-07-09 | 2009-05-05 | Koninklijke Philips Electronics N.V. | Light modulator |
AU2005333141A1 (en) * | 2004-07-16 | 2007-02-08 | Johnson & Johnson Consumer Companies, Inc. | Treatment of skin with light and benefit agent |
US7333698B2 (en) | 2004-08-05 | 2008-02-19 | Polyoptics Ltd | Optical scanning device |
US20060056589A1 (en) | 2004-08-31 | 2006-03-16 | Massachusetts Institute Of Technology | Radiation-induced cellular adaptive response |
US20060047281A1 (en) | 2004-09-01 | 2006-03-02 | Syneron Medical Ltd. | Method and system for invasive skin treatment |
US7519210B2 (en) | 2004-09-09 | 2009-04-14 | Raphael Hirsch | Method of assessing localized shape and temperature of the human body |
US20060079947A1 (en) | 2004-09-28 | 2006-04-13 | Tankovich Nikolai I | Methods and apparatus for modulation of the immune response using light-based fractional treatment |
KR20120088861A (en) | 2004-10-06 | 2012-08-08 | 가이디드 테라피 시스템스, 엘.엘.씨. | Method and system for controlled thermal treatment of human superficial tissue |
US20060122584A1 (en) | 2004-10-27 | 2006-06-08 | Bommannan D B | Apparatus and method to treat heart disease using lasers to form microchannels |
US20060094988A1 (en) | 2004-10-28 | 2006-05-04 | Tosaya Carol A | Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy |
US20060118127A1 (en) | 2004-12-06 | 2006-06-08 | Chinn Douglas O | Tissue protective system and method for thermoablative therapies |
AU2005314712A1 (en) | 2004-12-09 | 2006-06-15 | Palomar Medical Technologies, Inc. | Oral appliance with heat transfer mechanism |
JP2006192073A (en) | 2005-01-13 | 2006-07-27 | Matsushita Electric Ind Co Ltd | Phototherapy apparatus |
US8027710B1 (en) | 2005-01-28 | 2011-09-27 | Patrick Dannan | Imaging system for endoscopic surgery |
US20060173480A1 (en) | 2005-01-31 | 2006-08-03 | Yi Zhang | Safety penetrating method and apparatus into body cavities, organs, or potential spaces |
US7291141B2 (en) | 2005-02-02 | 2007-11-06 | Jay Harvey H | Method and apparatus for enhancing hair removal |
US7258695B2 (en) | 2005-02-08 | 2007-08-21 | Sonetics International | Hair restoration device and methods of using and manufacturing the same |
US20080183250A1 (en) | 2005-02-11 | 2008-07-31 | Hanafi Tanojo | Compositions and methods for treating or preventing skin inflammation via restoration of skin barrier function |
US20060253176A1 (en) | 2005-02-18 | 2006-11-09 | Palomar Medical Technologies, Inc. | Dermatological treatment device with deflector optic |
CN101132831A (en) | 2005-02-18 | 2008-02-27 | 帕洛玛医疗技术公司 | Dermatological treatment device |
US20060217787A1 (en) | 2005-03-23 | 2006-09-28 | Eastman Kodak Company | Light therapy device |
US20080294150A1 (en) | 2005-04-01 | 2008-11-27 | Palomar Medical Technologies, Inc. | Photoselective Islets In Skin And Other Tissues |
US7975702B2 (en) | 2005-04-05 | 2011-07-12 | El.En. S.P.A. | System and method for laser lipolysis |
US7856985B2 (en) | 2005-04-22 | 2010-12-28 | Cynosure, Inc. | Method of treatment body tissue using a non-uniform laser beam |
US8406858B2 (en) | 2005-04-29 | 2013-03-26 | The Regents Of The University Of Colorado, A Body Corporate | Multi-excitation diagnostic system and methods for classification of tissue |
US8127771B2 (en) | 2005-05-18 | 2012-03-06 | Cooltouch Incorporated | Treatment of cellulite and adipose tissue with mid-infrared radiation |
US7217265B2 (en) | 2005-05-18 | 2007-05-15 | Cooltouch Incorporated | Treatment of cellulite with mid-infrared radiation |
US7624640B2 (en) | 2005-06-03 | 2009-12-01 | Brown University | Opto-acoustic methods and apparatus for performing high resolution acoustic imaging and other sample probing and modification operations |
US20060293728A1 (en) | 2005-06-24 | 2006-12-28 | Roersma Michiel E | Device and method for low intensity optical hair growth control |
US7839972B2 (en) | 2005-07-22 | 2010-11-23 | Tomotherapy Incorporated | System and method of evaluating dose delivered by a radiation therapy system |
WO2007013008A1 (en) | 2005-07-26 | 2007-02-01 | Koninklijke Philips Electronics N.V. | Hair removing system |
CN101282692A (en) | 2005-08-08 | 2008-10-08 | 帕洛玛医疗技术公司 | Eye-safe photocosmetic device |
EP2656809A1 (en) | 2005-08-12 | 2013-10-30 | Board Of Regents, The University Of Texas System | Systems, devices, and methods for optically clearing tissue |
US20070093798A1 (en) | 2005-08-29 | 2007-04-26 | Reliant Technologies, Inc. | Method and Apparatus for Monitoring and Controlling Thermally Induced Tissue Treatment |
WO2007026382A1 (en) | 2005-08-30 | 2007-03-08 | Azienda Usl 4 Prato | Optical fiber laser device for ocular suturing |
WO2007030415A2 (en) | 2005-09-07 | 2007-03-15 | The Foundry, Inc. | Apparatus and method for disrupting subcutaneous structures |
US7967763B2 (en) | 2005-09-07 | 2011-06-28 | Cabochon Aesthetics, Inc. | Method for treating subcutaneous tissues |
CA2622560A1 (en) | 2005-09-15 | 2007-03-29 | Palomar Medical Technologies, Inc. | Skin optical characterization device |
US20070088206A1 (en) | 2005-10-14 | 2007-04-19 | Peyman Gholam A | Photoacoustic measurement of analyte concentration in the eye |
US20070121069A1 (en) | 2005-11-16 | 2007-05-31 | Andersen Dan E | Multiple spot photomedical treatment using a laser indirect ophthalmoscope |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
WO2007070881A2 (en) | 2005-12-15 | 2007-06-21 | Laser Abrasive Technologies, Llc | Method and apparatus for treatment of solid material including hard tissue |
DE102006001849A1 (en) | 2006-01-13 | 2007-07-19 | Siemens Ag | Mapping catheter for determining image data from the heart comprises a thermal sensor for determining temperature data on the tip of the catheter in the distal region of the catheter |
JP2007190566A (en) | 2006-01-17 | 2007-08-02 | Miyachi Technos Corp | Fiber laser beam machining apparatus |
CN101370460A (en) | 2006-01-20 | 2009-02-18 | 艾尔迈医疗公司 | Mechanical massage device |
US20070179470A1 (en) | 2006-02-01 | 2007-08-02 | Toombs Ella L | Disposable transparent liposuction cannula/handle |
US20070194717A1 (en) | 2006-02-17 | 2007-08-23 | Palomar Medical Technologies, Inc. | Lamp for use in a tissue treatment device |
US7727516B2 (en) | 2006-02-28 | 2010-06-01 | The Procter & Gamble Company | Reduction of hair growth |
JP4971373B2 (en) | 2006-03-06 | 2012-07-11 | ケアジェン シーオー エルティーディー | Peptide having insulin-like growth factor-1 activity and use thereof |
US7441224B2 (en) | 2006-03-09 | 2008-10-21 | Motorola, Inc. | Streaming kernel selection for reconfigurable processor |
US9675821B2 (en) | 2006-03-14 | 2017-06-13 | Boston Scientific Scimed, Inc. | Device for thermal treatment of tissue and for temperature measurement of tissue providing feedback |
EP1839705A1 (en) | 2006-03-27 | 2007-10-03 | Universidad de Alcala | Transcutaneous laser therapy patch |
US20070255355A1 (en) | 2006-04-06 | 2007-11-01 | Palomar Medical Technologies, Inc. | Apparatus and method for skin treatment with compression and decompression |
EP2008610A4 (en) | 2006-04-14 | 2012-03-07 | Sumitomo Electric Industries | Treatment device and treatment method |
WO2007122611A2 (en) | 2006-04-20 | 2007-11-01 | Nano Pass Technologies Ltd. | Device and methods combining vibrating micro-protrusions with phototherapy |
US20070260230A1 (en) | 2006-05-04 | 2007-11-08 | Reliant Technologies, Inc. | Opto-mechanical Apparatus and Method for Dermatological Treatment |
US8136531B2 (en) | 2006-05-08 | 2012-03-20 | Chariff Mark D | Device and method for treating musculo-skeletal injury and pain by application of laser light therapy |
US20070264625A1 (en) | 2006-05-11 | 2007-11-15 | Reliant Technologies, Inc. | Apparatus and Method for Ablation-Related Dermatological Treatment of Selected Targets |
DE102006023540A1 (en) | 2006-05-19 | 2007-11-22 | Francotyp-Postalia Gmbh | Process for the free spraying of the nozzles of an inkjet print head |
US8585707B2 (en) | 2006-06-07 | 2013-11-19 | Gary S. Rogers | Continuous low irradiance photodynamic therapy method |
CA2656042A1 (en) | 2006-06-27 | 2008-01-03 | Palomar Medical Technologies, Inc. | Handheld photocosmetic device |
US8786554B2 (en) | 2006-07-10 | 2014-07-22 | Atmel Corporation | Priority and combination suppression techniques (PST/CST) for a capacitive keyboard |
WO2008009005A2 (en) | 2006-07-13 | 2008-01-17 | Reliant Technologies, Inc. | Apparatus and method for adjustable fractional optical dermatological treatment |
US7586957B2 (en) | 2006-08-02 | 2009-09-08 | Cynosure, Inc | Picosecond laser apparatus and methods for its operation and use |
US20080058782A1 (en) | 2006-08-29 | 2008-03-06 | Reliant Technologies, Inc. | Method and apparatus for monitoring and controlling density of fractional tissue treatments |
US20080140164A1 (en) | 2006-12-06 | 2008-06-12 | Clrs Technology Corporation | Light emitting therapeutic devices and methods |
CA2674619A1 (en) | 2006-12-12 | 2008-06-19 | Brian D. Zelickson | Laser energy device for soft tissue removal |
WO2008074005A1 (en) | 2006-12-13 | 2008-06-19 | Palomar Medical Technologies, Inc. | Cosmetic and biomedical applications of ultrasonic energy and methods of generation thereof |
US20080154247A1 (en) | 2006-12-20 | 2008-06-26 | Reliant Technologies, Inc. | Apparatus and method for hair removal and follicle devitalization |
EP2106823A4 (en) | 2007-01-26 | 2010-10-27 | Panasonic Elec Works Co Ltd | Optical body hair growth regulating device |
US20080186591A1 (en) | 2007-02-01 | 2008-08-07 | Palomar Medical Technologies, Inc. | Dermatological device having a zoom lens system |
WO2008157782A1 (en) | 2007-06-21 | 2008-12-24 | Palomar Medical Technologies, Inc. | Eye-safe device for treatment of skin tissue |
EP2194899A4 (en) * | 2007-08-08 | 2012-11-28 | Tria Beauty Inc | Capacitive sensing method and device for detecting skin |
WO2009088550A2 (en) * | 2007-10-19 | 2009-07-16 | Lockheed Martin Corporation | System and method for conditioning animal tissue using laser light |
EP2561819B1 (en) | 2008-01-17 | 2015-01-07 | Syneron Medical Ltd. | Hair removal apparatus for personal use |
WO2009108933A2 (en) | 2008-02-28 | 2009-09-03 | Palomar Medical Technologies, Inc. | Systems and methods for treatment of soft tissue |
US20090222068A1 (en) | 2008-02-29 | 2009-09-03 | Clrs Technology Corporation | Rapid flash optical therapy |
WO2009117437A1 (en) | 2008-03-17 | 2009-09-24 | Palomar Medical Technologies, Inc. | Method and apparatus for fractional deformation and treatment of tissue |
WO2010017556A1 (en) | 2008-08-08 | 2010-02-11 | Palomar Medical Technologies, Inc | Method and apparatus for fractional deformation and treatment of cutaneous and subcutaneous tissue |
EP2331153A4 (en) | 2008-08-25 | 2014-01-15 | Laser Abrasive Technologies Llc | Method and apparatus for regeneration of oral cavity tissues |
US20100109041A1 (en) | 2008-11-06 | 2010-05-06 | Chun-Chiang Yin | High efficiency led structure |
US8410705B2 (en) | 2008-11-18 | 2013-04-02 | Ringdale, Inc. | LED lighting system with bypass circuit for failed LED |
US20130096546A1 (en) | 2009-03-05 | 2013-04-18 | Cynosure, Inc. | Non-uniform beam optical treatment methods and systems |
WO2010115209A2 (en) | 2009-04-03 | 2010-10-07 | Palomar Medical Technologies, Inc. | Method and apparatus for treatment of tissue |
US20100298744A1 (en) | 2009-04-30 | 2010-11-25 | Palomar Medical Technologies, Inc. | System and method of treating tissue with ultrasound energy |
JP5412979B2 (en) | 2009-06-19 | 2014-02-12 | コニカミノルタ株式会社 | Peripheral display device |
US20120116271A1 (en) | 2009-07-23 | 2012-05-10 | Palomar Medical Technologies, Inc. | Cellulite treatment |
US9919168B2 (en) | 2009-07-23 | 2018-03-20 | Palomar Medical Technologies, Inc. | Method for improvement of cellulite appearance |
US9014799B2 (en) | 2009-10-08 | 2015-04-21 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including electrically-actuated permeation enhancement |
JP2013516245A (en) | 2009-12-31 | 2013-05-13 | レーザー・アブレイシブ・テクノロジーズ・エルエルシー | Dental surgery laser with feedback mechanism |
CN102906497B (en) * | 2010-01-27 | 2016-08-17 | 熔合Uv系统公司 | The high heat load light-emitting device of microchannel cooling |
US20110257584A1 (en) | 2010-04-16 | 2011-10-20 | Palomar Medical Technologies, Inc. | Methods and devices for injection of a substance into tissue |
US20120099816A1 (en) | 2010-10-25 | 2012-04-26 | Palomar Medical Technologies, Inc. | Photonics module and method of manufacturing |
US20120277659A1 (en) | 2011-04-29 | 2012-11-01 | Palomar Medical Technologies, Inc. | Sensor-lotion system for use with body treatment devices |
KR102043476B1 (en) | 2011-10-17 | 2019-11-12 | 사운드 써지칼 테크놀로지 엘엘씨 | Ultrasonic probe for treating cellulite |
ES2842006T3 (en) | 2012-09-20 | 2021-07-12 | Vascomed Gmbh | Fiber optic force sensor, force measuring device and catheter |
-
2003
- 2003-06-19 KR KR1020047020627A patent/KR20050026404A/en not_active Application Discontinuation
- 2003-06-19 WO PCT/US2003/019280 patent/WO2004000098A2/en not_active Application Discontinuation
- 2003-06-19 CA CA002489506A patent/CA2489506A1/en not_active Abandoned
- 2003-06-19 EP EP03739201A patent/EP1539013A4/en not_active Withdrawn
- 2003-06-19 JP JP2004515915A patent/JP2005535370A/en active Pending
- 2003-06-19 BR BR0312430-4A patent/BR0312430A/en not_active Application Discontinuation
- 2003-06-19 AU AU2003245573A patent/AU2003245573A1/en not_active Abandoned
- 2003-06-19 CN CNB038198444A patent/CN1329008C/en not_active Expired - Fee Related
- 2003-06-19 US US10/465,757 patent/US7276058B2/en not_active Expired - Lifetime
-
2004
- 2004-12-12 IL IL16572404A patent/IL165724A0/en unknown
-
2007
- 2007-10-01 US US11/865,367 patent/US20080103565A1/en not_active Abandoned
-
2008
- 2008-02-15 US US12/032,004 patent/US8915948B2/en not_active Expired - Lifetime
-
2015
- 2015-01-02 US US14/588,746 patent/US20150165232A1/en not_active Abandoned
-
2017
- 2017-01-10 US US15/402,649 patent/US10556123B2/en not_active Expired - Fee Related
- 2017-01-10 US US15/402,693 patent/US10500413B2/en not_active Expired - Lifetime
Patent Citations (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2068721A (en) * | 1932-11-18 | 1937-01-26 | Wappler Frederick Charles | Method for electrosurgical severance of adhesions |
US2669771A (en) * | 1949-11-17 | 1954-02-23 | Gen Motors Corp | Armature coil lead staker |
US3793723A (en) * | 1971-12-03 | 1974-02-26 | Ultrasonic Systems | Ultrasonic replaceable shaving head and razor |
US3939560A (en) * | 1973-01-31 | 1976-02-24 | Wilkinson Sword Ltd. | Shaving equipment |
US3794028A (en) * | 1973-02-27 | 1974-02-26 | A Griffin | Method for injecting chemicals into the papilla for depilation |
US3858577A (en) * | 1974-04-05 | 1975-01-07 | Univ Southern California | Fiber optic laser light delivery system |
US4133503A (en) * | 1975-08-29 | 1979-01-09 | Bliss John H | Entry, display and use of data employed to overcome aircraft control problems due to wind shear |
US4139342A (en) * | 1977-07-18 | 1979-02-13 | Hughes Aircraft Company | Dye impregnated plastics for laser applications |
US4188927A (en) * | 1978-01-12 | 1980-02-19 | Valleylab, Inc. | Multiple source electrosurgical generator |
US4313431A (en) * | 1978-12-06 | 1982-02-02 | Messerschmitt-Boelkow-Blohm Gesellschaft Mit Beschraenkter Haftung | Endoscopic apparatus with a laser light conductor |
US4428368A (en) * | 1980-09-29 | 1984-01-31 | Masakatsu Torii | Massage device |
US4492601A (en) * | 1982-10-15 | 1985-01-08 | Daiichi Seito Kabushiki Kaisha | Process for clarifying and desalinating sugar cane syrup or molasses |
US4566271A (en) * | 1982-12-01 | 1986-01-28 | Lucas Industries Public Limited Company | Engine systems |
US4718416A (en) * | 1984-01-13 | 1988-01-12 | Kabushiki Kaisha Toshiba | Laser treatment apparatus |
US4799479A (en) * | 1984-10-24 | 1989-01-24 | The Beth Israel Hospital Association | Method and apparatus for angioplasty |
US4638800A (en) * | 1985-02-08 | 1987-01-27 | Research Physics, Inc | Laser beam surgical system |
US4741338A (en) * | 1986-10-06 | 1988-05-03 | Toshiaki Miyamae | Thermoelectric physical remedy apparatus |
US4890989A (en) * | 1987-02-12 | 1990-01-02 | Bernard Zimmern | Positive displacement machine with a plastic gate pinton |
US5380317A (en) * | 1988-06-10 | 1995-01-10 | Trimedyne Laser Systems, Inc. | Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium |
US4891817A (en) * | 1988-06-13 | 1990-01-02 | Eastman Kodak Company | Pulsed dye laser apparatus for high PRF operation |
US5180378A (en) * | 1989-04-24 | 1993-01-19 | Abiomed, Inc. | Laser surgery system |
US5486172A (en) * | 1989-05-30 | 1996-01-23 | Chess; Cyrus | Apparatus for treating cutaneous vascular lesions |
US4896329A (en) * | 1989-06-01 | 1990-01-23 | Exciton Incorporated | Laser dye liquids, laser dye instruments and methods |
US5281211A (en) * | 1989-06-07 | 1994-01-25 | University Of Miami, School Of Medicine, Dept. Of Ophthalmology | Noncontact laser microsurgical apparatus |
US5182557A (en) * | 1989-09-20 | 1993-01-26 | Semborg Recrob, Corp. | Motorized joystick |
US5080660A (en) * | 1990-05-11 | 1992-01-14 | Applied Urology, Inc. | Electrosurgical electrode |
US5488626A (en) * | 1991-01-14 | 1996-01-30 | Light Age, Inc. | Method of and apparatus for pumping of transition metal ion containing solid state lasers using diode laser sources |
US5484436A (en) * | 1991-06-07 | 1996-01-16 | Hemostatic Surgery Corporation | Bi-polar electrosurgical instruments and methods of making |
US5178617A (en) * | 1991-07-09 | 1993-01-12 | Laserscope | System for controlled distribution of laser dosage |
US5281216A (en) * | 1992-03-31 | 1994-01-25 | Valleylab, Inc. | Electrosurgical bipolar treating apparatus |
US6174325B1 (en) * | 1992-10-20 | 2001-01-16 | Esc Medical Systems Ltd. | Method and apparatus for therapeutic electromagnetic treatment |
US6171332B1 (en) * | 1992-10-23 | 2001-01-09 | Photo Therapeutics Limited | Light source |
US5486170A (en) * | 1992-10-26 | 1996-01-23 | Ultrasonic Sensing And Monitoring Systems | Medical catheter using optical fibers that transmit both laser energy and ultrasonic imaging signals |
US5383876A (en) * | 1992-11-13 | 1995-01-24 | American Cardiac Ablation Co., Inc. | Fluid cooled electrosurgical probe for cutting and cauterizing tissue |
US5707403A (en) * | 1993-02-24 | 1998-01-13 | Star Medical Technologies, Inc. | Method for the laser treatment of subsurface blood vessels |
US5860967A (en) * | 1993-07-21 | 1999-01-19 | Lucid, Inc. | Dermatological laser treatment system with electronic visualization of the area being treated |
US5386427A (en) * | 1994-02-10 | 1995-01-31 | Massachusetts Institute Of Technology | Thermally controlled lenses for lasers |
US5707401A (en) * | 1994-03-10 | 1998-01-13 | Esc Medical Systems, Ltd. | Apparatus for an efficient photodynamic treatment |
US6171301B1 (en) * | 1994-04-05 | 2001-01-09 | The Regents Of The University Of California | Apparatus and method for dynamic cooling of biological tissues for thermal mediated surgery |
US5595568A (en) * | 1995-02-01 | 1997-01-21 | The General Hospital Corporation | Permanent hair removal using optical pulses |
US5598426A (en) * | 1995-02-03 | 1997-01-28 | Candela Laser Corporation | Method and dye laser apparatus for producing long pulses of laser radiation |
US5707369A (en) * | 1995-04-24 | 1998-01-13 | Ethicon Endo-Surgery, Inc. | Temperature feedback monitor for hemostatic surgical instrument |
US6350276B1 (en) * | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US6675425B1 (en) * | 1996-03-21 | 2004-01-13 | Keiji Iimura | Photocatalytic apparatus and method for activating photocatalytic material |
US6338855B1 (en) * | 1996-10-25 | 2002-01-15 | The Procter & Gamble Company | Cleansing articles for skin and/or hair which also deposit skin care actives |
US6015404A (en) * | 1996-12-02 | 2000-01-18 | Palomar Medical Technologies, Inc. | Laser dermatology with feedback control |
US6508813B1 (en) * | 1996-12-02 | 2003-01-21 | Palomar Medical Technologies, Inc. | System for electromagnetic radiation dermatology and head for use therewith |
US5830208A (en) * | 1997-01-31 | 1998-11-03 | Laserlite, Llc | Peltier cooled apparatus and methods for dermatological treatment |
US6171302B1 (en) * | 1997-03-19 | 2001-01-09 | Gerard Talpalriu | Apparatus and method including a handpiece for synchronizing the pulsing of a light source |
US6511475B1 (en) * | 1997-05-15 | 2003-01-28 | The General Hospital Corporation | Heads for dermatology treatment |
US6104959A (en) * | 1997-07-31 | 2000-08-15 | Microwave Medical Corp. | Method and apparatus for treating subcutaneous histological features |
US20030009205A1 (en) * | 1997-08-25 | 2003-01-09 | Biel Merrill A. | Treatment device for topical photodynamic therapy and method of using same |
US6676654B1 (en) * | 1997-08-29 | 2004-01-13 | Asah Medico A/S | Apparatus for tissue treatment and having a monitor for display of tissue features |
US6171300B1 (en) * | 1997-09-04 | 2001-01-09 | Linvatec Corporation | Tubing cassette and method for cooling a surgical handpiece |
US6176854B1 (en) * | 1997-10-08 | 2001-01-23 | Robert Roy Cone | Percutaneous laser treatment |
US6340495B1 (en) * | 1997-12-16 | 2002-01-22 | Galderma Research & Development | Device including a chromophoric composition to be applied to the skin, a method of fabricating such a device, and uses therefor |
US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
US6508785B1 (en) * | 1998-03-06 | 2003-01-21 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
US6605080B1 (en) * | 1998-03-27 | 2003-08-12 | The General Hospital Corporation | Method and apparatus for the selective targeting of lipid-rich tissues |
US7060061B2 (en) * | 1998-03-27 | 2006-06-13 | Palomar Medical Technologies, Inc. | Method and apparatus for the selective targeting of lipid-rich tissues |
US6682524B1 (en) * | 1998-11-12 | 2004-01-27 | Asclepion Laser Technologies Gmbh | Dermatological hand piece |
US20030023283A1 (en) * | 1998-11-30 | 2003-01-30 | Mcdaniel David H. | Method and apparatus for the stimulation of hair growth |
US20040015156A1 (en) * | 1998-12-03 | 2004-01-22 | Vasily David B. | Method and apparatus for laser removal of hair |
US7097656B1 (en) * | 1999-03-18 | 2006-08-29 | Ls Private Joint-Stock Company | Device for the therapeutic and cosmetic photo-processing of biological tissue and method for using the same |
US20030004499A1 (en) * | 2000-01-13 | 2003-01-02 | Mcdaniel David H. | Method and apparatus for the photomodulation of living cells |
US20020004066A1 (en) * | 2000-02-29 | 2002-01-10 | Theodore Stanley | Transdermal drug patch with attached pocket for controlled heating device |
US20020005475A1 (en) * | 2000-04-28 | 2002-01-17 | Zenzie Henry H. | Contact detecting method and apparatus for an optical radiation handpiece |
US20020013572A1 (en) * | 2000-05-19 | 2002-01-31 | Berlin Michael S. | Delivery system and method of use for the eye |
US6503269B2 (en) * | 2000-06-12 | 2003-01-07 | Scott A. Nield | Method of treating intervertebral discs using optical energy and optical temperature feedback |
US20020002367A1 (en) * | 2000-06-30 | 2002-01-03 | Nikolai Tankovich | Twin light laser |
US6997923B2 (en) * | 2000-12-28 | 2006-02-14 | Palomar Medical Technologies, Inc. | Method and apparatus for EMR treatment |
US20060004347A1 (en) * | 2000-12-28 | 2006-01-05 | Palomar Medical Technologies, Inc. | Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor |
US20080009842A1 (en) * | 2000-12-28 | 2008-01-10 | The General Hospital Corporation | Method and apparatus for emr treatment |
US20030023284A1 (en) * | 2001-02-20 | 2003-01-30 | Vladimir Gartstein | Method and apparatus for the in-vivo treatment of pathogens |
US6989007B2 (en) * | 2001-02-21 | 2006-01-24 | Solx, Inc. | Devices and techniques for treating glaucoma |
US6682523B2 (en) * | 2001-02-21 | 2004-01-27 | John H. Shadduck | Devices and techniques for treating trabecular meshwork |
US20060009750A1 (en) * | 2001-03-02 | 2006-01-12 | Palomar Medical Technologies, Inc. | Apparatus and method for treatment using a patterned mask |
US6503486B2 (en) * | 2001-03-12 | 2003-01-07 | Colgate Palmolive Company | Strip for whitening tooth surfaces |
US6679837B2 (en) * | 2001-06-01 | 2004-01-20 | Intlas Ltd. | Laser light irradiation apparatus |
US20030018373A1 (en) * | 2001-06-15 | 2003-01-23 | Uv-Solutions, Llc | Method and apparatus for sterilizing or disinfecting a region on a patient |
US20030009158A1 (en) * | 2001-07-09 | 2003-01-09 | Perricone Nicholas V. | Skin treatments using blue and violet light |
US6986903B2 (en) * | 2001-07-13 | 2006-01-17 | Mibelle Ag Cosmetics | Methods for treatment of human skin damaged by laser treatment or chemical peelings and compositions useful in such methods |
US20030023235A1 (en) * | 2001-07-27 | 2003-01-30 | Cense Abraham Josephus | Skin treating device comprising a processor for determination of the radiation pulse dose |
US20060013533A1 (en) * | 2001-12-10 | 2006-01-19 | Inolase 2002 Ltd. | Method and apparatus for improving safety during exposure to a monochromatic light source |
US20040010298A1 (en) * | 2001-12-27 | 2004-01-15 | Gregory Altshuler | Method and apparatus for improved vascular related treatment |
US7170034B2 (en) * | 2002-02-05 | 2007-01-30 | Radiancy Inc. | Pulsed electric shaver |
US20040019120A1 (en) * | 2002-03-12 | 2004-01-29 | Gracie Vargas | Laser treatment of cutaneous vascular lesions |
US7367341B2 (en) * | 2002-03-15 | 2008-05-06 | The General Hospital Corporation | Methods and devices for selective disruption of fatty tissue by controlled cooling |
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US20040015158A1 (en) * | 2002-07-19 | 2004-01-22 | To-Mu Chen | Transilluminator device |
WO2004033040A1 (en) * | 2002-10-07 | 2004-04-22 | Palomar Medical Technologies, Inc. | Apparatus for performing photobiostimulation |
US6991644B2 (en) * | 2002-12-12 | 2006-01-31 | Cutera, Inc. | Method and system for controlled spatially-selective epidermal pigmentation phototherapy with UVA LEDs |
US7160289B2 (en) * | 2003-03-28 | 2007-01-09 | Vandolay, Inc. | Vascular occlusion systems and methods |
US6989023B2 (en) * | 2003-07-08 | 2006-01-24 | Oralum, Llc | Hygienic treatments of body structures |
US20040006332A1 (en) * | 2003-07-08 | 2004-01-08 | Michael Black | Hygienic treatments of body structures |
US20050015077A1 (en) * | 2003-07-14 | 2005-01-20 | Yevgeniy Kuklin | Method and apparatus for skin treatment using near infrared laser radiation |
US20060020309A1 (en) * | 2004-04-09 | 2006-01-26 | Palomar Medical Technologies, Inc. | Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor |
US20060004306A1 (en) * | 2004-04-09 | 2006-01-05 | Palomar Medical Technologies, Inc. | Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor |
US20060007965A1 (en) * | 2004-07-12 | 2006-01-12 | Nikolai Tankovich | Passive Q-switch modulated fiber laser |
US20080004611A1 (en) * | 2004-10-05 | 2008-01-03 | Koninklijke Philips Electronics N.V. | Skin Treatment Device with Radiation Emission Protection |
US20080004608A1 (en) * | 2006-06-30 | 2008-01-03 | Alcon, Inc. | Multifunction surgical probe |
US20100021867A1 (en) * | 2006-11-27 | 2010-01-28 | Rejuvedent Llc | Method and apparatus for hard tissue treatment and modification |
US20100015576A1 (en) * | 2007-01-16 | 2010-01-21 | Rejuvedent Llc | Method and apparatus for diagnostic and treatment using hard tissue or material microperforation |
US20090018531A1 (en) * | 2007-06-08 | 2009-01-15 | Cynosure, Inc. | Coaxial suction system for laser lipolysis |
US20090018624A1 (en) * | 2007-07-13 | 2009-01-15 | Juniper Medical, Inc. | Limiting use of disposable system patient protection devices |
US20090024192A1 (en) * | 2007-07-16 | 2009-01-22 | Spamedica International Srl | Method and device for minimally invasive skin and fat treatment |
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Also Published As
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US20150165232A1 (en) | 2015-06-18 |
US20170182334A1 (en) | 2017-06-29 |
US8915948B2 (en) | 2014-12-23 |
JP2005535370A (en) | 2005-11-24 |
CN1329008C (en) | 2007-08-01 |
BR0312430A (en) | 2005-04-26 |
IL165724A0 (en) | 2006-01-15 |
CN1674837A (en) | 2005-09-28 |
EP1539013A2 (en) | 2005-06-15 |
US10500413B2 (en) | 2019-12-10 |
US7276058B2 (en) | 2007-10-02 |
US20090024193A1 (en) | 2009-01-22 |
EP1539013A4 (en) | 2005-09-21 |
US10556123B2 (en) | 2020-02-11 |
US20170182335A1 (en) | 2017-06-29 |
US20040073079A1 (en) | 2004-04-15 |
WO2004000098A2 (en) | 2003-12-31 |
WO2004000098A3 (en) | 2004-05-13 |
KR20050026404A (en) | 2005-03-15 |
CA2489506A1 (en) | 2003-12-31 |
AU2003245573A1 (en) | 2004-01-06 |
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