Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberUS20060270895 A1
Publication typeApplication
Application numberUS 11/418,499
Publication date30 Nov 2006
Filing date3 May 2006
Priority date6 Jun 2001
Also published asCA2449689A1, DE60134790D1, EP1395324A2, EP1395324B1, US7048680, US20020188166, US20040138519, US20060270891, WO2002098499A2, WO2002098499A3
Publication number11418499, 418499, US 2006/0270895 A1, US 2006/270895 A1, US 20060270895 A1, US 20060270895A1, US 2006270895 A1, US 2006270895A1, US-A1-20060270895, US-A1-2006270895, US2006/0270895A1, US2006/270895A1, US20060270895 A1, US20060270895A1, US2006270895 A1, US2006270895A1
InventorsAnthony Viole, Laksen Sirimanne, Steven Bolling, Shawn O'Leary, Wolfgang Werner
Original AssigneeAnthony Viole, Laksen Sirimanne, Bolling Steven F, O'leary Shawn, Wolfgang Werner
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Multilumen catheter for minimizing limb ischemia
US 20060270895 A1
Abstract
A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.
Images(5)
Previous page
Next page
Claims(7)
1. A method of treating a patient, comprising:
inserting a multilumen cannula having a first lumen and a second lumen into the patient at a first blood vessel;
advancing the multilumen cannula within the vasculature until the first lumen is in fluid communication with a first vascular location and the second lumen is in fluid communication with a second vascular location remote from the first vascular location;
providing fluid communication between the first lumen and an inflow portion of a pump and between the second lumen and an outflow portion of the pump;
withdrawing blood through the second lumen from the second vascular location;
delivering blood through the first lumen to the first vascular location; and
redirecting blood flow at a distal end of the first lumen so that blood exiting the lumen is directed into the first vascular location in substantially the same direction of the flow at the first vascular location.
2. The method of claim 1, wherein redirecting further comprises forming said first lumen with a curved at said first distal end such that blood exiting the lumen is directed back along the multilumen catheter.
3. The method of claim 1, wherein the multilumen cannula is advanced until the first lumen is in fluid communication with a first blood vessel and the second lumen is in fluid communication with a second vessel blood, a branch blood vessel being located between the first and second blood vessels.
4. The method of claim 1, wherein the multilumen cannula is advanced until the second lumen is in fluid communication with a femoral artery.
5. The method of claim 3, wherein the multilumen cannula is advanced until the first lumen is in fluid communication with the aorta.
6. The method of claim 1, wherein the multilumen cannula is advanced until the first lumen is in fluid communication with the aorta.
7. The method of claim 1, wherein the multilumen further comprises at least one aperture extending from at least one of the first lumen and the second lumen, the method further comprising delivering blood through the at least one aperture to lessen the effects of ischemia in the vasculature due to the presence of the multilumen cannula.
Description
    RELATED APPLICATIONS
  • [0001]
    This application is a division of U.S. application Ser. No. 09/876,281, filed Jun. 6, 2001, which is hereby incorporated by reference herein in its entirety.
  • BACKGROUND OF THE INVENTION
  • [0002]
    1. Field of the Invention
  • [0003]
    The present invention relates to a multilumen catheter and, in particular, to multilumen catheters designed to prevent ischemia in patients when the catheter is positioned within the body.
  • [0004]
    2. Description of the Related Art
  • [0005]
    It is often necessary to divert the flow of blood from a patient's blood vessel back to the same or a different blood vessel as part of treating a patient suffering from one or more of numerous health impairments, including cardiovascular disease, such as congestive heart failure. Although surgical cut-down procedures can achieve this, percutaneous insertion of catheters has made this procedure less invasive and therefore less traumatic to the patient. Still, insertion of a cannula into the circulatory system can cause complex, and sometimes adverse, reactions within the body.
  • [0006]
    Some of the percutaneous procedures involve removing blood from the body and subsequently returning it to the body. For example, dialysis treatment involves first removing blood from the patient's circulatory system, treating the blood outside of the body, and then returning the blood to the patient's circulatory system to perfuse the various tissues and organs. Depending on the volume of blood flow, cannulae with large carrying capacity may be necessary. By maximizing the cross-sectional area of the cannula, the volume of blood that may be removed and/or returned to the patient's vascular system via the cannula is maximized. One approach to maximize the cross-sectional area of the cannula involves using either two single lumen catheters or a multi-lumen catheter. In a recirculation application, one lumen would function to withdraw blood and one would function to return blood to the patient. One problem with using two single lumen catheters is that it subjects the patient to multiple percutaneous insertion procedures, which complicates the procedure and increases the potential for infection and other complications. Therefore, it would be desirable to have a catheter assembly which could be inserted into the patient through a single insertion site.
  • [0007]
    Multilumen catheters in various forms have been employed for this purpose. For example, multilumen catheters have been made with two, three or more lumens to serve various aspiration and infusion functions, including extracting and returning blood to vessels, taking blood samples for testing and providing medications to the patient's vascular system. Simple multilumen catheters have been made by providing two round catheters of equal or nearly equal length joined by a web, or thin strip. This approach is described in U.S. Pat. No. 5,776,111 to Tesio. Other multilumen catheter designs have a unitary body with at least one septum dividing the lumens which extend from a proximal to a distal end.
  • [0008]
    While multilumen catheters require only a single puncture of the epidermis, their performance is limited in at least two ways. For one, the outer perimeter of the multilumen catheter cannot exceed the inner diameter of the vessel into which it is inserted. Furthermore, the already limited cross-sectional area must be divided into at least two lumens, one for withdrawal and one for return. Thus the carrying capacity of each lumen is further reduced. To supply the same amount of blood, the velocity and pressure of the blood in the lumens must increase over what it would be in the vessel itself. This has the potential to cause damage to the vessel as blood comes jetting out of the return lumen. Also, it may put further stress upon blood cells, even causing hemolysis. Thus, multilumen catheters must be made as large as possible to carry enough blood at satisfactory conditions.
  • [0009]
    Where the size of a catheter approaches the interior size of a vessel, less and less blood can flow around the catheter. As a result, limited blood supply reaches tissues and organs located downstream of the catheter in the vascular system. With insufficient perfusion, the tissues downstream of the lumen insertion site suffer from ischemia and become oxygen deprived. Prolonged oxygen deprivation can lead to tissue damage, as is well known in the art. Therefore, it would be desirable to have a multilumen catheter that can maximize cross-sectional area of withdrawal and return lumens while at the same time providing for acceptable levels of blood perfusion of tissue downstream of the catheter insertion site in the vascular system. It would also be advantageous to have a multilumen catheter that can also remove blood from one peripheral vessel and return blood to a second peripheral vessel.
  • SUMMARY OF THE INVENTION
  • [0010]
    Overcoming many if not all of the limitations of the prior art, the present invention comprises a multilumen catheter for directing the flow of blood to and from a patient through a single cannulation site. The catheter comprises a proximal end, a first distal end and a second distal end. The first distal end extends further from the proximal end than the second distal end. A first lumen extends between the first distal end and the proximal end and a second lumen extends between the second distal end and the proximal end. At least one aperture, but preferably a plurality of apertures may be formed in one of the first or second lumens positioned near the proximal end so that the aperture permits active maintenance or enhancement of perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. In an alternative embodiment, the multilumen catheter further comprises a third lumen with distal and proximal ends configured to be positioned entirely within the patient's vascular system. This third lumen is configured to permit the passive flow of blood downstream of the catheter site to maintain or enhance perfusion.
  • [0011]
    In one embodiment, a connector formed in the shape of a Y (“Y-connector”) is positioned at the proximal end of the multilumen catheter. One leg of the Y-connector is in fluid communication with the first lumen and the other leg of the Y-connector is in fluid communication with the second lumen.
  • [0012]
    Preferably, in an application of the present invention, an outflow conduit of a pumping system is fluidly engaged to one lumen of the multilumen catheter and an inflow conduit of the same system is fluidly engaged to the other lumen. The inflow and outflow conduits are fluidly coupled to a pump so that, when connected to the patient, the pump circulates blood from one distal end of the multilumen catheter to the other distal end, and also through at least one aperture in one of the first or second lumens positioned near the proximal end. In one application, the multilumen catheter of the present invention is incorporated into an extracardiac pumping system for supplementing blood circulation in a patient without any component thereof being connected to the patient's heart. Such a system is described in U.S. Pat. No. 6,200,260, which is incorporated herein by reference. The system includes, in addition to the multilumen catheter, a pump configured to pump blood through the patient at subcardiac rates, an inflow conduit fluidly coupled to the pump to divert blood to the pump from a first blood vessel, and an outflow conduit fluidly coupled to the pump to direct blood from the pump to a second blood vessel.
  • [0013]
    The present invention also provides a method for treating a patient using the multilumen catheter of the present invention. The method comprises the step of inserting the multilumen catheter described above into the patient at a single cannulation site of a first blood vessel, locating the catheter such that a first lumen may be in fluid communication with a second blood vessel and a second lumen may be in fluid communication with the first blood vessel, withdrawing blood from one of said blood vessels through one of the first or said second lumens, and delivering blood through the other of said first or second lumens so that blood is delivered upstream and downstream of the cannulation site.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0014]
    These and other features and advantages of the invention will now be described with reference to the drawings, which are intended to illustrate and not to limit the invention.
  • [0015]
    FIG. 1 is a schematic of one embodiment of the present invention multilumen catheter.
  • [0016]
    FIG. 2 is a schematic of an alternative embodiment of the present invention multilumen catheter.
  • [0017]
    FIG. 3 is a schematic of an alternative embodiment of the present invention multilumen catheter with a distal end comprising a J-tip configuration.
  • [0018]
    FIG. 4 is a schematic of an alternative embodiment of the present invention multilumen catheter comprising a Y-connector.
  • [0019]
    FIG. 5 is a schematic of one application of one embodiment of the multilumen catheter to a patient.
  • [0020]
    FIG. 6 is an enlarged view of a portion the proximal end of the embodiment shown in FIG. 1 applied to a patient.
  • [0021]
    FIG. 7 is an enlarged view of a portion the proximal end of the embodiment shown in FIG. 2 applied to a patient.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
  • [0022]
    Turning now to the drawings provided herein, a more detailed description of the embodiments of the present invention is provided below.
  • [0023]
    With reference to FIG. 1, one embodiment of the present invention comprises a multilumen catheter 10 designed to lessen ischemia that can occur when a large diameter catheter is inserted into a patient's blood vessel. The multilumen catheter preferably is of unitary construction and requires only one entry point into the patient's body. The multilumen catheter 10 comprises at least two lumens: a first lumen 12 and a second lumen 14. The first lumen 12 extends from a proximal end 16 of the multilumen catheter 10 to a first distal end 18. The second lumen 14 extends from the proximal end 16 of the multilumen catheter 10 to a second distal end 20. The lumens 12, 14 of the multilumen catheter 10 may be arranged one of many different ways. For example, the two lumens may be joined in a side-by-side manner, forming a “figure-8” when viewed from the proximal end 16. Alternately, a single cylindrical catheter housing may contain within it two or more side-by-side lumens. A cylindrical catheter housing could be formed with a diametral septum, i.e. a wall, extending across the cylinder at a diameter. A cylindrical housing with concentrically positioned lumens is also contemplated.
  • [0024]
    The first distal end 18 may be formed with one or more distal apertures 22, although such apertures may also be located in the second distal end 20. The distal apertures 22 may be positioned close together or spaced circumferentially around the distal end. The apertures 22 serve to decrease the pressure drop across the cannula tip, thereby minimizing damage to vessel walls from jetting effects. It may also be appropriate to practice methods for directing blood flow so as to minimize damage to vessel walls from jetting effects and from the recoil effect on the catheter of blood exiting a catheter. The present invention may further comprise a tapered tip 24 at the first distal end 18, which facilitates insertion and threading of the catheter into the patient. The present invention may also further comprise a tapered tip 26 at the second distal end 20.
  • [0025]
    One preferred embodiment of the multilumen catheter further comprises a set of apertures 28 positioned on the catheter 10 near the proximal end 16. The apertures 28 are formed on at least one lumen of the catheter to provide for fluid communication between one of the lumens 12, or 14 of the multilumen catheter 10 and the blood vessel in which it resides. A radiopaque marker 30 may be positioned at the distal end 18 of the multilumen catheter 10. The multilumen catheter could further comprise markings 32 near the proximal end of the multilumen catheter which are a known distance from one or more of the distal ends. These markings 32, as well as the marker 30 can be used to accurately position the catheter when applied to the patient.
  • [0026]
    In another embodiment of the present multilumen catheter shown in FIG. 2, the multilumen catheter 110 comprises a third lumen 134 extending between a proximal end 136 and a distal end 138. The lumen 134 is positioned and sized such that when the multilumen catheter 110 is applied to the patient (described below), the lumen resides entirely within the patient's body. As described above, the lumen 134 may be connected to the catheter 110 in a variety of ways. The purpose of the third lumen 134 is configured to permit the passive flow of blood downstream to the catheter to enhance perfusion. The embodiment shown in FIG. 2 also may have apertures 128 disposed near the proximal end 116 of the multilumen catheter 110. As described above, this embodiment may further comprise a tapered tip 140 at the distal end of the third lumen 134 and a tapered tip 142 at the proximal end of the third lumen 134 to facilitate application of the catheter to the patient.
  • [0027]
    In one variation of the three lumen embodiment the third lumen 134 may be made of collapsible material. In the collapsed state, the third lumen 134 would conform to at least a portion of the outside surface of the multilumen catheter 110. Once applied to the patient, as described in more detail below, the lumen 134 would be expanded to the deployed state shown in FIG. 2. This collapsible lumen could comprise a stone basket, or a frame similar to a stent. A stone basket is a structure that can be deployed within a patient's body and is used to capture objects. Here, the basket is used primarily to create a space between the catheter 110 and the vessel wall to permit the passive flow of blood downstream of the catheter site to enhance perfusion.
  • [0028]
    In an alternate embodiment of the multilumen catheter 210, shown in FIG. 3, the first distal end 218 is formed in the shape of a J-tip. That is, the opening at the distal end 218 may be curved such that blood exiting the lumen 212 is directed back along the multilumen catheter 210. Distal aperture(s) 222 may be formed at the bend of the J-tip so that blood also exits the lumen 212 and flows distal of the catheter 210. The “J” shape of the multi-lumen catheter tip may be formed and/or maintained by pre-loading it with a coil or with wire reinforcement, or by using a shape-memory material to create and maintain this shape. If the catheter is inserted so that the tip is straight and the “J” shape is deployed after the catheter inserted into the patient, the catheter may comprise a tapered tip at the first distal end 218, as described above.
  • [0029]
    Referring to FIG. 4, yet another alternative embodiment of the present invention multilumen catheter 310 comprises a Y-connector 334 formed at the proximal end of the multilumen catheter 310. As described above, the lumens are separated in any suitable way such that fluid communication is provided between the distal end 318 of the lumen 312 of the multilumen catheter 310 and the proximal end 336 of one leg of the Y-connector 334, and fluid communication is provided between the distal end 320 of the lumen 314 of the catheter 310 and the proximal end 338 of one leg of the Y-connector 334.
  • [0030]
    Any of the multilumen catheters described herein may be made from various materials to improve their viability in long-term treatment applications. For example, it is preferred that the biocompatibility of the catheter be improved compared to uncoated catheters to prevent adverse reactions such as compliment activation and the like. To prevent such side effects, the interior lumens of the catheters can be coated with biocompatible materials. Also known in the art are anti-bacterial coatings. Such coatings may be very useful on the outer surface of the catheter. This is especially true at or about where the catheter enters the patient's skin. At such a location, the patient is vulnerable to introduction of bacteria into the body cavity. Anti-bacterial coatings can reduce the likelihood of infection and thus improve the viability of long-term treatments.
  • [0031]
    In one application, the multilumen catheter of the present invention may be integrated into a pumping system, such as the one described in more detail in U.S. Pat. No. 6,200,260. Referring to FIG. 5, such a system comprises the multilumen catheter 10, an inflow conduit 38, an outflow conduit 40 and a pump 42. One end of the outflow conduit 40 may be connected to the proximal end of the lumen 12, while the other end is connected to the inlet of the pump 42. One end of the inflow conduit 38 may be connected to the proximal end of the lumen 14, while the other end is connected to the outlet of the pump 42. This results in a flow from the first distal end 18 to the second distal end 20. Of course, the flow direction may be reversed using the same multilumen catheter, resulting in a flow from distal end 20 to distal end 18. In that case, the outflow conduit 40 is connected to the proximal end of lumen 14 and the inflow conduit 38 is connected to the proximal end of lumen 12. Referring to FIG. 5, the present multilumen catheter 10 when incorporated into a pumping system may be applied to a patient in an arterial-arterial fashion. Where the multilumen catheter 10 is inserted into the femoral artery 44 of the patient 46. The radiopaque marker 30 which may be incorporated into the distal end 18 of the multilumen catheter is used to track the insertion of the catheter so that to catheter may be positioned at a desired site within the patient's vascular system. As mentioned above, markings 32 on the proximal end could also be used to locate the distal end or ends.
  • [0032]
    In one example, the distal end 18 may be located in the aortic arch 48. The pump draws blood from the patient's vascular system in the area near the distal end 18 and into the lumen 12. This blood is further drawn into the lumen of the conduit 40 and into the pump 42. The pump 42 then expels the blood into the lumen of the outflow conduit 38. This lumen carries the blood into the lumen 14 of the multilumen catheter 10 and back into the patient's vascular system in the area near the distal end 20. As described in greater detail below regarding FIGS. 6 and 7, the apertures 28 and/or the third lumen 134 provide blood flow to the patient's vasculature downstream of where the multilumen catheter resides in the vasculature to maintain or enhance perfusion of blood. The blood flow in the multilumen catheter may be reversed. In that case, blood is drawn from the patient through distal end 20 and returned to the patient through distal end 18.
  • [0033]
    Referring to FIG. 6, the multilumen catheter 10 comprises features that will maintain or increase the blood flow to downstream tissue when the catheter is inserted into the patient. The apertures 28 provide for fluid communication between at least one lumen 12 or 14 and the patient's blood vessel. The apertures 28, thus, provides active perfusion of the downstream tissues.
  • [0034]
    Referring to FIG. 7, the lumen 134 of the embodiment shown in FIG. 2 is located entirely within the vessel when the catheter 110 is inserted into the patient. The lumen provides a pathway for blood flow to tissue downstream of the catheter so that the catheter 110 may maintain or increase the flow of blood to downstream tissue. The lumen 134, thus, provides passive perfusion. If desired, apertures may be included in one of the other two lumens to supplement passive perfusion with active perfusion.
  • [0035]
    The invention may be embodied in other specific forms without departing from its spirit or essential characteristics. The described embodiment is to be considered in all respects only as illustrative and not restrictive and the scope of the invention is, therefore, indicated by the appended claims rather than by the foregoing description. All changes which come within the meaning and range of equivalency of the claims are to be embraced within their scope.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US1902418 *2 Nov 193121 Mar 1933Jensen Salsbery Lab IncSurgical instrument
US2876769 *11 Oct 195510 Mar 1959Cordova Jose JuanApparatus for oxygenating, centrifuging and changing the temperature of blood
US2935068 *4 Aug 19553 May 1960Donaldson John ShearmanSurgical procedure and apparatus for use in carrying out the same
US3017885 *30 Mar 195923 Jan 1962Robicsek FrancisBlood flow meter
US3410263 *13 May 196512 Nov 1968Westinghouse Electric CorpBlood-pumping apparatus provided with heart synchronizing means
US3938530 *15 Nov 197417 Feb 1976Santomieri LouisCatheter
US4080958 *27 Feb 197628 Mar 1978Datascope CorporationApparatus for aiding and improving the blood flow in patients
US4134402 *5 Jul 197716 Jan 1979Mahurkar Sakharam DDouble lumen hemodialysis catheter
US4149535 *6 May 197717 Apr 1979Gist-Brocades N.V.Catheter holding device
US4375941 *8 Sep 19808 Mar 1983Child Frank WMethod and apparatus for pumping blood
US4405313 *29 Jan 198220 Sep 1983Sisley James RFigure-eight, dual-lumen catheter and method of using
US4459977 *19 Feb 198217 Jul 1984Veronique PizonCoronary sinus retroperfusion apparatus for the treatment of myocardial ischemia
US4464164 *24 Sep 19827 Aug 1984Extracorporeal Medical Specialties, Inc.Flowrate control for a blood flow system
US4540402 *20 Apr 198310 Sep 1985Karl AignerDouble perfusion catheter
US4543087 *14 Nov 198324 Sep 1985Quinton Instrument CompanyDouble lumen catheter tip
US4692141 *29 Jan 19868 Sep 1987Mahurkar Sakharam DDouble lumen catheter
US4897077 *23 Nov 198830 Jan 1990Kontron Inc.Method of inserting an IAB device into the body
US4902272 *17 Jun 198720 Feb 1990Abiomed Cardiovascular, Inc.Intra-arterial cardiac support system
US4944745 *29 Feb 198831 Jul 1990Scimed Life Systems, Inc.Perfusion balloon catheter
US4957504 *2 Dec 198818 Sep 1990Chardack William MImplantable blood pump
US4960411 *30 Jun 19882 Oct 1990Medtronic Versaflex, Inc.Low profile sterrable soft-tip catheter
US4985014 *11 Jul 198915 Jan 1991Orejola Wilmo CVentricular venting loop
US4995857 *7 Apr 198926 Feb 1991Arnold John RLeft ventricular assist device and method for temporary and permanent procedures
US5000734 *26 Jan 198919 Mar 1991Georges BoussignacProbe intended to be introduced within a living body
US5014715 *22 Nov 198814 May 1991Chapolini Robert JDevice for measuring the impedance to flow of a natural or prosthetic vessel in a living body
US5059167 *14 May 199022 Oct 1991Retroperfusion Systems, Inc.Retroperfusion and retroinfusion control apparatus, system and method
US5087247 *28 Aug 199011 Feb 1992Cardiovascular Designs, Inc.Balloon perfusion catheter
US5129883 *26 Jul 199114 Jul 1992Michael BlackCatheter
US5147281 *23 Apr 199015 Sep 1992Advanced Medical Systems, Inc.Biological fluid pumping means and method
US5186713 *1 Nov 199016 Feb 1993Baxter International Inc.Extracorporeal blood oxygenation system and method for providing hemoperfusion during transluminal balloon angioplasty procedures
US5318518 *7 Aug 19927 Jun 1994Hp Medica Gesellschaft Mbh Fur Medizintechnische SystemeIrrigating catheter
US5378230 *1 Nov 19933 Jan 1995Mahurkar; Sakharam D.Triple-lumen critical care catheter
US5403291 *2 Aug 19934 Apr 1995Quinton Instrument CompanyCatheter with elongated side holes
US5437601 *17 Feb 19941 Aug 1995Runge; Thomas M.Blood conduit and pulsatile cardiopulmonary bypass pump system
US5486159 *1 Oct 199323 Jan 1996Mahurkar; Sakharam D.Multiple-lumen catheter
US5522800 *16 Dec 19944 Jun 1996Cardiovascular Dynamics, Inc.Low profile perfusion catheter
US5533957 *18 May 19959 Jul 1996Trustees Of Boston UniversityMethod of tissue retroperfusion
US5536250 *13 Sep 199416 Jul 1996Localmed, Inc.Perfusion shunt device and method
US5542937 *24 Jun 19946 Aug 1996Target Therapeutics, Inc.Multilumen extruded catheter
US5554136 *27 Feb 199510 Sep 1996Luther Medical Products, Inc.Dual lumen infusion/aspiration catheter
US5556390 *7 Mar 199517 Sep 1996Quinton Instrument CompanyCatheter with oval or elliptical lumens
US5571093 *21 Sep 19945 Nov 1996Cruz; CosmeMultiple-lumen catheter
US5616137 *22 Feb 19951 Apr 1997Minnesota Mining And Manufacturing CompanyLow velocity aortic cannula
US5618267 *6 Oct 19958 Apr 1997Palestrant; Aubrey M.Method for establishing collapsible infusion conduit
US5722930 *7 Jun 19953 Mar 1998Electric Boat CorporationReciprocating pump circulatory assist arrangement
US5746709 *25 Apr 19965 May 1998Medtronic, Inc.Intravascular pump and bypass assembly and method for using the same
US5766151 *7 Jun 199516 Jun 1998Heartport, Inc.Endovascular system for arresting the heart
US5776111 *7 Nov 19967 Jul 1998Medical Components, Inc.Multiple catheter assembly
US5785686 *15 Jul 199728 Jul 1998Runge; Thomas M.Cannula system for a biventricular cardiac support system or a cardiopulmonary bypass system
US5795326 *29 Jan 199718 Aug 1998Baxter International Inc.Double lumen tubing design for catheter
US5807311 *29 Nov 199615 Sep 1998Palestrant; Aubrey M.Dialysis catheter having rigid and collapsible lumens and related method
US5868703 *6 Dec 19969 Feb 1999Endoscopic Technologies, Inc.Multichannel catheter
US5928181 *21 Nov 199727 Jul 1999Advanced International Technologies, Inc.Cardiac bypass catheter system and method of use
US5947953 *6 Aug 19977 Sep 1999Hemocleanse, Inc.Splittable multiple catheter assembly and methods of inserting the same
US5961486 *5 Nov 19985 Oct 1999Twardowski; Zbylut J.Clot resistant multiple lumen catheter
US5965089 *3 Oct 199712 Oct 1999United States Surgical CorporationCirculatory support system
US6044845 *3 Feb 19984 Apr 2000Salient Interventional Systems, Inc.Methods and systems for treating ischemia
US6053900 *7 Oct 199825 Apr 2000Brown; Joe E.Apparatus and method for delivering diagnostic and therapeutic agents intravascularly
US6059760 *23 Jan 19989 May 2000Medtronic, Inc.Cannula having reverse flow tip
US6083198 *25 Jun 19984 Jul 2000Cardiovention, Inc.Perfusion catheter providing segmented flow regions and methods of use
US6135981 *22 Oct 199724 Oct 2000Dyke; Charles C.Protective aortic occlusion catheter
US6167765 *25 Sep 19982 Jan 2001The Regents Of The University Of MichiganSystem and method for determining the flow rate of blood in a vessel using doppler frequency signals
US6200260 *2 Oct 199813 Mar 2001Fore Flow CorporationImplantable heart assist system
US6245045 *23 Apr 199912 Jun 2001Alexander Andrew StratienkoCombination sheath and catheter for cardiovascular use
US6287608 *11 Apr 200011 Sep 2001Intellicardia, Inc.Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney by infusion of a vasodilator
US6293958 *27 Jul 199825 Sep 2001Acist Medical Systems, Inc.Catheter having flow diffusing tip
US6299575 *25 Apr 20009 Oct 2001Orqis Medical CorporationImplantable heart assist system
US6371935 *20 Aug 199916 Apr 2002Cardeon CorporationAortic catheter with flow divider and methods for preventing cerebral embolization
US6383172 *2 Apr 19997 May 2002Coaxia, Inc.Retrograde venous perfusion with isolation of cerebral circulation
US6387037 *23 Dec 199914 May 2002Orqis Medical CorporationImplantable heart assist system and method of applying same
US6390969 *21 Apr 200021 May 2002Orqis Medical CorporationImplantable heart assist system and method of applying same
US6409700 *22 Mar 199925 Jun 2002Cfd Research CorporationDouble lumen catheter
US6428464 *9 Apr 19996 Aug 2002Orqis Medical CorporationImplantable heart assist system
US6508777 *6 May 199921 Jan 2003Cardeon CorporationCirculatory support system and method of use for isolated segmental perfusion
US6514226 *10 Feb 20004 Feb 2003Chf Solutions, Inc.Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney
US6558356 *25 Apr 20006 May 2003Coaxia, Inc.Medical device for flow augmentation in patients with occlusive cerebrovascular disease and methods of use
US6592567 *7 Dec 199915 Jul 2003Chf Solutions, Inc.Kidney perfusion catheter
US6610004 *15 Feb 200226 Aug 2003Orqis Medical CorporationImplantable heart assist system and method of applying same
US6685621 *11 Jun 20023 Feb 2004Orois Medical CorporationImplantable heart assist system and method of applying same
US6719749 *1 Jun 200013 Apr 2004Medical Components, Inc.Multilumen catheter assembly and methods for making and inserting the same
US6889082 *6 Nov 20023 May 2005Orqis Medical CorporationImplantable heart assist system and method of applying same
US7048680 *6 Jun 200123 May 2006Orqis Medical CorporationMultilumen catheter for minimizing limb ischemia
US7125376 *7 Apr 200324 Oct 2006Orqis Medical CorporationImplantable heart assist system and method of applying same
US20020111577 *9 Feb 200115 Aug 2002Laksen SirimanneExtra-corporeal vascular conduit
US20020169413 *21 May 200214 Nov 2002Libra Medical Systems, Inc.Apparatus and methods for treating congestive heart disease
US20030040736 *25 Jun 199927 Feb 2003John H. StevensEndovacular cardiac venting catheter and method
US20030083617 *8 Nov 20021 May 2003Coaxia, Inc.Partial aortic occlusion devices and methods for renal and coronary perfusion augmentation
US20030144628 *2 Dec 200231 Jul 2003Laksen SirimannePercutaneous catheter assembly
US20040116768 *5 Dec 200317 Jun 2004Bolling Steven F.Implantable heart assist system and method of applying same
US20040138519 *22 Dec 200315 Jul 2004Anthony VioleMultilumen catheter for minimizing limb ischemia
US20040236172 *28 Jun 200425 Nov 2004Bolling Steven F.Implantable heart assist system and method of applying same
US20050085683 *15 Oct 200321 Apr 2005Bolling Steven F.Implantable heart assist system and method of applying same
US20050113631 *12 Nov 200326 May 2005Bolling Steven F.Cannulae having a redirecting tip
US20050131385 *12 Dec 200316 Jun 2005Bolling Steven F.Cannulae for selectively enhancing blood flow
US20050256363 *3 May 200517 Nov 2005Bolling Steven FImplantable heart assist system and method of applying same
US20060264689 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
US20060264693 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
US20060264694 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
US20060264797 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US20020188167 *14 Feb 200212 Dec 2002Anthony VioleMultilumen catheter for minimizing limb ischemia
US20050113631 *12 Nov 200326 May 2005Bolling Steven F.Cannulae having a redirecting tip
US20060264693 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
US20060264694 *3 May 200623 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
US20060270891 *3 May 200630 Nov 2006Anthony VioleMultilumen catheter for minimizing limb ischemia
Classifications
U.S. Classification600/16
International ClassificationA61M25/16, A61M1/36, A61M25/00, A61M25/14, A61N1/362, A61M1/12
Cooperative ClassificationA61M1/10, A61M1/3653, A61M1/3613, A61M2025/0031, A61M2025/0037, A61M1/122, A61M1/3659
European ClassificationA61M1/36C7