EP1904653A4 - Microfluidic methods and apparatuses for sample preparation and analysis - Google Patents

Microfluidic methods and apparatuses for sample preparation and analysis

Info

Publication number
EP1904653A4
EP1904653A4 EP06787065A EP06787065A EP1904653A4 EP 1904653 A4 EP1904653 A4 EP 1904653A4 EP 06787065 A EP06787065 A EP 06787065A EP 06787065 A EP06787065 A EP 06787065A EP 1904653 A4 EP1904653 A4 EP 1904653A4
Authority
EP
European Patent Office
Prior art keywords
apparatuses
analysis
sample preparation
microfluidic methods
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06787065A
Other languages
German (de)
French (fr)
Other versions
EP1904653A2 (en
Inventor
Gregory R Yantz
Jonathan W Larson
Rudolf Gilmanshin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Genomics Inc
Original Assignee
US Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Genomics Inc filed Critical US Genomics Inc
Publication of EP1904653A2 publication Critical patent/EP1904653A2/en
Publication of EP1904653A4 publication Critical patent/EP1904653A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
EP06787065A 2005-07-18 2006-07-13 Microfluidic methods and apparatuses for sample preparation and analysis Withdrawn EP1904653A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70048005P 2005-07-18 2005-07-18
US70068905P 2005-07-18 2005-07-18
US70049005P 2005-07-18 2005-07-18
PCT/US2006/027111 WO2007011622A2 (en) 2005-07-18 2006-07-13 Microfluidic methods and apparatuses for sample preparation and analysis

Publications (2)

Publication Number Publication Date
EP1904653A2 EP1904653A2 (en) 2008-04-02
EP1904653A4 true EP1904653A4 (en) 2010-04-14

Family

ID=37669351

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06787065A Withdrawn EP1904653A4 (en) 2005-07-18 2006-07-13 Microfluidic methods and apparatuses for sample preparation and analysis

Country Status (3)

Country Link
EP (1) EP1904653A4 (en)
JP (1) JP2009501938A (en)
WO (1) WO2007011622A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2580589C (en) 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
EP3628729A3 (en) * 2007-07-16 2020-05-06 California Institute of Technology Arrays, devices, methods and systems for detecting target molecules
US8551763B2 (en) 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
WO2009155704A1 (en) 2008-06-25 2009-12-30 Fio Corporation Bio-threat alert system
WO2010022519A1 (en) 2008-08-29 2010-03-04 Fio Corporation A single-use handheld diagnostic test device, and an associated system and method for testing biological and environmental test samples
EP2387721A4 (en) 2009-01-13 2014-05-14 Fio Corp A handheld diagnostic test device and method for use with an electronic device and a test cartridge in a rapid diagnostic test
US8202486B2 (en) * 2009-08-12 2012-06-19 Caliper Life Sciences, Inc. Pinching channels for fractionation of fragmented samples
US9139426B2 (en) 2010-09-21 2015-09-22 The University Of North Carolina At Chapel Hill Methods, systems and devices for forming nanochannels
WO2013039778A2 (en) 2011-09-12 2013-03-21 The University Of North Carolina At Chapel Hill Devices with a fluid transport nanochannel intersected by a fluid sensing nanochannel and related methods
WO2013119765A1 (en) * 2012-02-10 2013-08-15 The University Of North Carolina At Chapel Hill Devices with fluidic nanofunnels, associated methods, fabrication and analysis systems
KR20150132125A (en) 2013-02-28 2015-11-25 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis
NZ711033A (en) 2013-03-13 2020-03-27 Univ North Carolina Chapel Hill Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis
EP3295148A4 (en) 2015-05-11 2018-11-07 The University of North Carolina at Chapel Hill Fluidic devices with nanoscale manifolds for molecular transport, related systems and methods of analysis
US11499183B2 (en) 2017-06-28 2022-11-15 Bio-Rad Laboratories, Inc. System and method for droplet detection
US11045805B2 (en) 2017-11-01 2021-06-29 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
US10898895B2 (en) 2018-09-13 2021-01-26 Talis Biomedical Corporation Vented converging capillary biological sample port and reservoir
CN113498362B (en) * 2019-02-27 2023-01-20 京瓷株式会社 Particle separation measuring device and particle separation measuring apparatus

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000416A2 (en) * 2001-06-20 2003-01-03 Teragenics, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US6506609B1 (en) * 1999-05-17 2003-01-14 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US20030159999A1 (en) * 2002-02-04 2003-08-28 John Oakey Laminar Flow-Based Separations of Colloidal and Cellular Particles
EP1380337A2 (en) * 2002-07-12 2004-01-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
US6770182B1 (en) * 2000-11-14 2004-08-03 Sandia National Laboratories Method for producing a thin sample band in a microchannel device
US20050112606A1 (en) * 2003-04-10 2005-05-26 Martin Fuchs Advanced microfluidics

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793705A (en) * 1987-10-07 1988-12-27 The United States Of America As Represented By The United States Department Of Energy Single molecule tracking
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
JP3123249B2 (en) * 1991-09-10 2001-01-09 株式会社日立製作所 DNA molecule length measuring method and measuring device
EP0682671A4 (en) * 1993-02-01 1998-01-14 Seq Ltd Methods and apparatus for dna sequencing.
DE69825601T2 (en) * 1997-02-12 2005-04-28 Chan, Eugene Y, Brookline METHOD FOR THE ANALYSIS OF POLYMERS
US6790671B1 (en) * 1998-08-13 2004-09-14 Princeton University Optically characterizing polymers
US6818395B1 (en) * 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
WO2003048295A1 (en) * 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506609B1 (en) * 1999-05-17 2003-01-14 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6770182B1 (en) * 2000-11-14 2004-08-03 Sandia National Laboratories Method for producing a thin sample band in a microchannel device
WO2003000416A2 (en) * 2001-06-20 2003-01-03 Teragenics, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US20030159999A1 (en) * 2002-02-04 2003-08-28 John Oakey Laminar Flow-Based Separations of Colloidal and Cellular Particles
EP1380337A2 (en) * 2002-07-12 2004-01-14 Tosoh Corporation Fine channel device and a chemically operating method for fluid using the device
US20050112606A1 (en) * 2003-04-10 2005-05-26 Martin Fuchs Advanced microfluidics

Also Published As

Publication number Publication date
JP2009501938A (en) 2009-01-22
WO2007011622A3 (en) 2007-05-24
EP1904653A2 (en) 2008-04-02
WO2007011622A2 (en) 2007-01-25

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20080206

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DAX Request for extension of the european patent (deleted)
RBV Designated contracting states (corrected)

Designated state(s): DE FR GB

RIN1 Information on inventor provided before grant (corrected)

Inventor name: LARSON, JONATHAN, W.

Inventor name: GILMANSHIN, RUDOLF

Inventor name: YANTZ, GREGORY, R.

A4 Supplementary search report drawn up and despatched

Effective date: 20100316

17Q First examination report despatched

Effective date: 20100715

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Effective date: 20101126