DE69912983D1 - Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel - Google Patents

Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel

Info

Publication number
DE69912983D1
DE69912983D1 DE69912983T DE69912983T DE69912983D1 DE 69912983 D1 DE69912983 D1 DE 69912983D1 DE 69912983 T DE69912983 T DE 69912983T DE 69912983 T DE69912983 T DE 69912983T DE 69912983 D1 DE69912983 D1 DE 69912983D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
compositions containing
containing paclitaxel
water mixable
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69912983T
Other languages
English (en)
Inventor
Joseph Rubinfeld
Rajashree Joshi
Y Gore
Rajesh Shrotriya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astex Pharmaceuticals Inc
Original Assignee
Supergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supergen Inc filed Critical Supergen Inc
Application granted granted Critical
Publication of DE69912983D1 publication Critical patent/DE69912983D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69912983T 1998-10-30 1999-09-22 Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel Expired - Lifetime DE69912983D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/183,199 US6017948A (en) 1998-10-30 1998-10-30 Water-miscible pharmaceutical compositions
PCT/US1999/021990 WO2000025775A1 (en) 1998-10-30 1999-09-22 Water-miscible pharmaceutical compositions of paclitaxel

Publications (1)

Publication Number Publication Date
DE69912983D1 true DE69912983D1 (de) 2003-12-24

Family

ID=22671864

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69912983T Expired - Lifetime DE69912983D1 (de) 1998-10-30 1999-09-22 Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel

Country Status (11)

Country Link
US (1) US6017948A (de)
EP (1) EP1124549B1 (de)
JP (1) JP2002528494A (de)
CN (1) CN1178655C (de)
AT (1) ATE254455T1 (de)
AU (1) AU775158B2 (de)
CA (1) CA2345697A1 (de)
DE (1) DE69912983D1 (de)
IL (1) IL142720A (de)
MX (1) MXPA01004268A (de)
WO (1) WO2000025775A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US6040330A (en) * 1999-01-08 2000-03-21 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of taxanes
US6828346B2 (en) * 1999-10-25 2004-12-07 Supergen, Inc. Methods for administration of paclitaxel
US6136846A (en) 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
WO2002072150A2 (en) * 2001-03-13 2002-09-19 Angiotech Pharmaceuticals Inc. Micellar drug delivery vehicles and uses thereof
DE10115740A1 (de) * 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
DE60220519T2 (de) 2001-04-20 2007-09-27 The University Of British Columbia, Vancouver Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe
US20030126788A1 (en) * 2001-11-07 2003-07-10 Colloid Tech. Inc. Storage stable translucent flammable article
US6537985B1 (en) 2001-11-30 2003-03-25 Phoenix Scientific, Inc. Antibiotic formulation and a method of making this formulation
MXPA04005038A (es) * 2001-11-30 2004-08-11 Bristol Myers Squibb Co Solvatos de paclitaxel.
WO2004006889A1 (en) * 2002-07-15 2004-01-22 Alcon, Inc. Bioerodible film for ophthalmic drug delivery
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
ES2579235T3 (es) 2005-06-29 2016-08-08 Threshold Pharmaceuticals, Inc. Profármacos Alquilantes de Fosforamidato
US9943490B2 (en) * 2007-11-05 2018-04-17 The Trustees Of Princeton University Composite flash-precipitated nanoparticles
CN101909614B (zh) 2007-12-24 2015-04-15 太阳医药高级研发有限公司 纳米分散体
WO2010048330A1 (en) * 2008-10-21 2010-04-29 Threshold Pharmaceuticals, Inc. Treatment of cancer using hypoxia activated prodrugs
CA2765541A1 (en) 2009-06-19 2010-12-23 Sun Pharma Advanced Research Company Ltd. Nanodispersion of a drug and process for its preparation
SG185389A1 (en) 2010-05-03 2012-12-28 Teikoku Pharma Usa Inc Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
US20120172796A1 (en) 2010-12-30 2012-07-05 Chappa Ralph A Composition for intravascular delivery of therapeutic composition
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN112972419B (zh) * 2019-12-02 2024-03-08 四川科伦药物研究院有限公司 一种白蛋白纳米药物组合物的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5034397A (en) * 1985-12-12 1991-07-23 Bristol-Myers Squibb Co. Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone
US4772589A (en) * 1986-10-29 1988-09-20 Bristol-Myers Etoposide solution in NMP
WO1990014094A1 (en) * 1989-05-26 1990-11-29 Abbott Laboratories Injectable clarithromycin composition
US5082863A (en) * 1990-08-29 1992-01-21 Schering Corporation Pharmaceutical composition of florfenicol
CA2086874E (en) * 1992-08-03 2000-01-04 Renzo Mauro Canetta Methods for administration of taxol
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
NZ292690A (en) * 1994-09-01 1998-06-26 Upjohn Co Parenteral formulations comprising a lazaroid steroid, buffer, cosolvent and water
AU4652596A (en) * 1995-01-09 1996-07-31 Atrix Laboratories, Inc. Liquid polymer delivery system
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
CZ293747B6 (cs) * 1995-12-21 2004-07-14 Pfizer Inc. Vodný farmaceutický roztok vhodný pro injekční podávání hostiteli a jeho použití
US5773422A (en) * 1996-01-29 1998-06-30 Komer; Gene Avermectin formulation
US5877205A (en) * 1996-06-28 1999-03-02 Board Of Regents, The University Of Texas System Parenteral paclitaxel in a stable non-toxic formulation
CA2211949A1 (en) * 1997-07-21 1999-01-29 David Farley Johnson Nonaqueous compositions for parenteral administration
US5922754A (en) * 1998-10-02 1999-07-13 Abbott Laboratories Pharmaceutical compositions containing paclitaxel

Also Published As

Publication number Publication date
EP1124549B1 (de) 2003-11-19
US6017948A (en) 2000-01-25
ATE254455T1 (de) 2003-12-15
WO2000025775A1 (en) 2000-05-11
CN1178655C (zh) 2004-12-08
AU6397799A (en) 2000-05-22
AU775158B2 (en) 2004-07-22
IL142720A0 (en) 2002-03-10
CA2345697A1 (en) 2000-05-11
IL142720A (en) 2005-03-20
JP2002528494A (ja) 2002-09-03
EP1124549A1 (de) 2001-08-22
MXPA01004268A (es) 2002-06-04
CN1368880A (zh) 2002-09-11

Similar Documents

Publication Publication Date Title
DE69912983D1 (de) Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel
ATE253620T1 (de) Farbmittelzubereitungen
DE29806504U1 (de) Azidfreie, gaserzeugende Zusammensetzung
TR200100922T2 (tr) Aktif maddelerin akciğerler yolu ile tatbik edilmesi.
WO2001087824A3 (en) 7-substituted fused ring tetracycline compounds
NO20003930D0 (no) Sammensetninger som inneholder organiske forbindelser
EA199900749A1 (ru) Фармацевтическая композиция
AR028162A1 (es) Disponibilidad controlada de compuestos de formulacion, composiciones y metodos para el lavado que utilizan los mismos.
NO20031648L (no) Farmasöytiske lösninger av modafinilforbindelser
DE59902827D1 (de) Azidfreie, gaserzeugende Zusammensetzung
NO983530L (no) Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
AU2002225369A1 (en) Photobase generators, curable compositions prepared by using the same and process of curing
PA8577701A1 (es) Polipeptido t20 pegilado
NO20050019L (no) Polytylenglykolaldehyd-derivater
DE69902493D1 (de) Härtbare, photochromische Zusammensetzung
SE9903290D0 (sv) Novel compounds
DE50010265D1 (de) Azidfreie gaserzeugende Zusammensetzung
RS51534B (en) NEW COMPOUND OF SINUSOID IF CURRENT INHIBITORS AND CALCIUM INHIBITOR AND PHARMACEUTICAL MIXTURE CONTAINED BY IT
AU4714297A (en) Metalloproteinase inhibitors
ID21353A (id) Senyawa bi-aromatik yang terikat melalui radikal heteroetilena, serta komposisi farmasi dan kosmetik yang mengandungnya
EA200400670A1 (ru) Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи
EA200300128A1 (ru) Фармацевтические композиции, содержащие карбонат лития
AU2002230579A1 (en) Calcilytic compounds
DE29821544U1 (de) Azidfreie, gaserzeugende Zusammensetzung
AR022646A1 (es) MOLÉCULA POLINUCLEOTíDICA QUE COMPRENDE UNA SECUENCIA DE STREPTOMYCES AVERMITILES QUE DIRIGE LA RELACIoN DE AVERMICTINAS B2: B1, VECTOR RECOMBINANTE, CÉLULA HUÉSPED, PROCEDIMIENTO PARA OBTENER NUEVA CEPA DE S.AVERMITILIS, CÉLULA DE S.AVERMITILES Y COMPOSICIoN DE CICLOHEXIL B2: CICLOHEXIL B1 AVERMECT

Legal Events

Date Code Title Description
8332 No legal effect for de