DE69832167D1 - Identifizierung von gegenständen mittels mehrfacher bilderfassungen - Google Patents

Identifizierung von gegenständen mittels mehrfacher bilderfassungen

Info

Publication number
DE69832167D1
DE69832167D1 DE69832167T DE69832167T DE69832167D1 DE 69832167 D1 DE69832167 D1 DE 69832167D1 DE 69832167 T DE69832167 T DE 69832167T DE 69832167 T DE69832167 T DE 69832167T DE 69832167 D1 DE69832167 D1 DE 69832167D1
Authority
DE
Germany
Prior art keywords
brightfield
excitation
stained
fetal
fluorescence images
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832167T
Other languages
English (en)
Other versions
DE69832167T2 (de
Inventor
Ilya Ravkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Microsystems San Jose Corp
Original Assignee
Applied Imaging Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Imaging Corp filed Critical Applied Imaging Corp
Publication of DE69832167D1 publication Critical patent/DE69832167D1/de
Application granted granted Critical
Publication of DE69832167T2 publication Critical patent/DE69832167T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G01N15/1433
    • G01N2015/012
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology

Landscapes

  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Testing Of Coins (AREA)
  • Table Devices Or Equipment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE69832167T 1997-05-14 1998-05-12 Identifizierung von gegenständen mittels mehrfacher bilderfassungen Expired - Lifetime DE69832167T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4647097P 1997-05-14 1997-05-14
US46470P 1997-05-14
US72502 1998-05-04
US09/072,502 US6169816B1 (en) 1997-05-14 1998-05-04 Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
PCT/US1998/009689 WO1998052018A1 (en) 1997-05-14 1998-05-12 Identification of objects by means of multiple imaging

Publications (2)

Publication Number Publication Date
DE69832167D1 true DE69832167D1 (de) 2005-12-08
DE69832167T2 DE69832167T2 (de) 2006-07-20

Family

ID=26723956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832167T Expired - Lifetime DE69832167T2 (de) 1997-05-14 1998-05-12 Identifizierung von gegenständen mittels mehrfacher bilderfassungen

Country Status (11)

Country Link
US (1) US6169816B1 (de)
EP (1) EP0981732B1 (de)
JP (1) JP2002514304A (de)
AT (1) ATE308747T1 (de)
AU (1) AU739834B2 (de)
CA (1) CA2289930C (de)
DE (1) DE69832167T2 (de)
HK (1) HK1029170A1 (de)
IL (1) IL132747A (de)
NO (1) NO995542L (de)
WO (1) WO1998052018A1 (de)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6320697B2 (en) * 1931-08-07 2001-11-20 Nikon Corporation Illuminating light selection device for a microscope
US6215892B1 (en) * 1995-11-30 2001-04-10 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
US6718053B1 (en) * 1996-11-27 2004-04-06 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
US6259807B1 (en) 1997-05-14 2001-07-10 Applied Imaging Corp. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
KR100303608B1 (ko) * 1997-05-22 2001-11-22 박호군 혈구세포자동인식방법및장치
AU754722B2 (en) * 1998-05-09 2002-11-21 Ikonisys Inc. Method and apparatus for computer controlled rare cell, including fetal cell, based diagnosis
JP2002529704A (ja) * 1998-10-29 2002-09-10 セル ワークス インコーポレイテッド 単一細胞の複数マーカー特徴付け
US6539106B1 (en) * 1999-01-08 2003-03-25 Applied Materials, Inc. Feature-based defect detection
JP4624513B2 (ja) * 1999-01-19 2011-02-02 オリンパス株式会社 顕微鏡用撮像装置
WO2000047998A1 (en) 1999-02-10 2000-08-17 Cell Works Inc. Class characterization of circulating cancer cells isolated from body fluids and methods of use
DE19911988C2 (de) * 1999-03-17 2003-07-31 Siemens Ag Medizinische Magnetresonanzanlage
US6876760B1 (en) 2000-12-04 2005-04-05 Cytokinetics, Inc. Classifying cells based on information contained in cell images
US7151847B2 (en) * 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
DE19932870A1 (de) * 1999-07-09 2001-04-05 Friedrich Schiller Uni Jena Bu Vorrichtung zur optischen Partikel- und Partikelströmungsanalyse
EP1227686B1 (de) * 1999-09-01 2005-06-22 Hamamatsu Photonics K.K. Farbbildaufnahmegerät für schwaches licht
WO2001033196A2 (en) * 1999-10-29 2001-05-10 Veracel Inc. Controlled review of medical sample
US6692952B1 (en) * 1999-11-10 2004-02-17 Massachusetts Institute Of Technology Cell analysis and sorting apparatus for manipulation of cells
US20060073509A1 (en) * 1999-11-18 2006-04-06 Michael Kilpatrick Method for detecting and quantitating multiple subcellular components
US6542180B1 (en) * 2000-01-07 2003-04-01 Mitutoyo Corporation Systems and methods for adjusting lighting of a part based on a plurality of selected regions of an image of the part
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7518652B2 (en) 2000-05-03 2009-04-14 Aperio Technologies, Inc. Method and apparatus for pre-focus in a linear array based slide scanner
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
EP1322788A2 (de) * 2000-06-23 2003-07-02 Cytokinetics, Inc. Bildanalyse zur bestimmung des phenotyps von mutantenzellen-gruppen
US7218764B2 (en) * 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US6956961B2 (en) * 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
US7016787B2 (en) * 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
SE517626C3 (sv) * 2001-04-12 2002-09-04 Cellavision Ab Förfarande vid mikroskopering för att söka av och positionera ett objekt, där bilder tas och sammanfogas i samma bildkoordinatsystem för att noggrant kunna ställa in mikroskopbordet
US20040157211A1 (en) * 2001-06-08 2004-08-12 Ole Skyggebjerg Method and a system for counting cells from a plurality of species
US7133543B2 (en) * 2001-06-12 2006-11-07 Applied Imaging Corporation Automated scanning method for pathology samples
EP1406081A4 (de) * 2001-07-03 2011-10-05 Hitachi Ltd Verfahren und vorrichtung zur optischen messung biologischer proben
US7336988B2 (en) * 2001-08-08 2008-02-26 Lucent Technologies Inc. Multi-photon endoscopy
WO2003042788A2 (en) * 2001-11-13 2003-05-22 Chromavision Medical Systems, Inc. A system for tracking biological samples
US7272252B2 (en) * 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
US20050037406A1 (en) * 2002-06-12 2005-02-17 De La Torre-Bueno Jose Methods and apparatus for analysis of a biological specimen
JP2004163413A (ja) * 2002-08-28 2004-06-10 Carl-Zeiss-Stiftung Trading As Carl Zeiss 顕微鏡システムおよび顕微鏡検査方法
ES2375724T3 (es) 2002-09-27 2012-03-05 The General Hospital Corporation Dispositivo microflu�?dico para seperación de células y sus usos.
US9487823B2 (en) * 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US8043834B2 (en) * 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
US20040202357A1 (en) 2003-04-11 2004-10-14 Perz Cynthia B. Silhouette image acquisition
US20070160503A1 (en) * 2003-06-13 2007-07-12 Palaniappan Sethu Microfluidic systems for size based removal of red blood cells and platelets from blood
US20050009032A1 (en) * 2003-07-07 2005-01-13 Cytokinetics, Inc. Methods and apparatus for characterising cells and treatments
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
WO2005010677A2 (en) * 2003-07-18 2005-02-03 Cytokinetics, Inc. Characterizing biological stimuli by response curves
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US7251363B2 (en) * 2003-07-29 2007-07-31 Ventana Medical Systems, Inc. Method and system for creating an image mask
US7440101B2 (en) * 2004-01-23 2008-10-21 Beckman Coulter, Inc. System and method for multiple laser triggering
JP4271054B2 (ja) * 2004-02-12 2009-06-03 オリンパス株式会社 細胞画像解析装置
US20050273271A1 (en) * 2004-04-05 2005-12-08 Aibing Rao Method of characterizing cell shape
JP5134365B2 (ja) 2004-05-27 2013-01-30 アペリオ・テクノロジーズ・インコーポレイテッド 三次元仮想スライドを生成しかつ可視化するためのシステム及び方法
US7653260B2 (en) * 2004-06-17 2010-01-26 Carl Zeis MicroImaging GmbH System and method of registering field of view
US8582924B2 (en) * 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US20070031818A1 (en) * 2004-07-15 2007-02-08 Cytokinetics, Inc., A Delaware Corporation Assay for distinguishing live and dead cells
US7323318B2 (en) * 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
US7612769B2 (en) * 2004-09-14 2009-11-03 E.I. Du Pont De Nemours And Company Computer-implemented methods for organizing image data produced by resonant Mie scattering of light from microparticles and resulting data structures
EP1791979A4 (de) * 2004-09-22 2009-07-29 Ikonisys Inc Verfahren zum nachweis und zur quantifizierung mehrerer subzellulärer komponenten
EP1863908B1 (de) * 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8164622B2 (en) 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070031043A1 (en) * 2005-08-02 2007-02-08 Perz Cynthia B System for and method of intelligently directed segmentation analysis for automated microscope systems
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
WO2007080583A2 (en) * 2006-01-10 2007-07-19 Applied Spectral Imaging Ltd. Methods and systems for analyzing biological samples
DE102006020885A1 (de) * 2006-05-05 2007-11-08 Qiagen Gmbh Einführung von Sequenzelementen in Nukleinsäuren
JP5157901B2 (ja) 2006-06-08 2013-03-06 株式会社ニコン 観察装置
JP4678601B2 (ja) * 2006-08-15 2011-04-27 横河電機株式会社 創薬スクリーニング装置
EP2614832B1 (de) * 2007-02-12 2016-07-13 A1M Pharma AB Diagnose und Behandlung von Präeklampsie
EP2156370B1 (de) 2007-05-14 2011-10-12 Historx, Inc. Abteilungsauftrennung durch pixelcharakterisierung unter verwendung von bilddatenclusterung
ES2599902T3 (es) * 2007-06-15 2017-02-06 Novartis Ag Sistema y método de microscopio para obtener datos de muestra normalizados
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
US7936913B2 (en) * 2007-08-07 2011-05-03 Nextslide Imaging Llc Network image review in clinical hematology
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
US7978258B2 (en) * 2007-08-31 2011-07-12 Historx, Inc. Automatic exposure time selection for imaging tissue
DE102007062067A1 (de) * 2007-12-21 2009-07-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optisches Verfahren und Vorrichtung zur Klassifizierung von Partikeln
WO2009106081A1 (en) 2008-02-29 2009-09-03 Dako Denmark A/S Systems and methods for tracking and providing workflow information
CA2719020C (en) * 2008-03-21 2014-07-08 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
WO2009124997A1 (en) 2008-04-11 2009-10-15 Universität Leipzig Method and kit for the ex vivo evaluation of the response of a tumor to conditions to be tested
JP5407015B2 (ja) * 2008-07-10 2014-02-05 国立大学法人徳島大学 画像処理装置、画像処理方法、コンピュータ実行可能な画像処理プログラム、及び顕微鏡システム
WO2010012002A1 (en) * 2008-07-25 2010-01-28 Saryna Medical Corporation Methods and systems for genetic analysis of fetal nucleated red blood cells
US9240043B2 (en) * 2008-09-16 2016-01-19 Novartis Ag Reproducible quantification of biomarker expression
EP3764085A3 (de) 2008-10-24 2021-03-24 Leica Biosystems Imaging Inc. Fluoreszenz-scanner mit komplettobjektträger
JP4997255B2 (ja) * 2009-01-05 2012-08-08 オリンパス株式会社 細胞画像解析装置
FR2942899B1 (fr) * 2009-03-03 2011-09-23 Jose Balbuena Dispositif et procede d'analyse optique de documents
US8187979B2 (en) * 2009-12-23 2012-05-29 Varian Semiconductor Equipment Associates, Inc. Workpiece patterning with plasma sheath modulation
CN102762712A (zh) 2010-01-21 2012-10-31 百赛普有限公司 稀有细胞的磁性分离
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
JP5495934B2 (ja) * 2010-05-18 2014-05-21 キヤノン株式会社 画像処理装置、その処理方法及びプログラム
CA2807228C (en) * 2010-08-05 2016-02-16 Abbott Point Of Care, Inc. Method and apparatus for automated whole blood sample analyses from microscopy images
JP5668436B2 (ja) * 2010-12-01 2015-02-12 ソニー株式会社 検体領域検出方法、検体領域検出装置及び検体領域検出プログラム
US8339586B2 (en) 2011-04-15 2012-12-25 Constitution Medical, Inc. Measuring volume and constituents of cells
JP5413408B2 (ja) 2011-06-09 2014-02-12 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
EP2725341A4 (de) * 2011-06-27 2015-02-25 Sysmex Corp Zellanalysator
WO2013157319A1 (ja) * 2012-04-18 2013-10-24 オリンパス株式会社 光分析を用いた単一粒子検出装置、単一粒子検出方法及び単一粒子検出用コンピュータプログラム
JP6343660B2 (ja) * 2013-03-11 2018-06-13 ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド 血球の撮像
JP6128998B2 (ja) * 2013-07-09 2017-05-17 富士フイルム株式会社 遺伝毒性又は骨髄毒性評価方法及び遺伝毒性又は骨髄毒性評価キット
US20150030215A1 (en) * 2013-07-26 2015-01-29 Abbott Point Of Care, Inc. Method and apparatus for producing an image of undiluted whole blood sample having wright stain coloration
EP3178942A4 (de) * 2014-08-05 2017-08-23 Fujifilm Corporation Verfahren zum testen fötaler chromosomen
WO2016138064A1 (en) * 2015-02-24 2016-09-01 Nanoscopia (Cayman), Inc. Off-axis dark field and fluorescence illumination
DE102016109945A1 (de) * 2015-11-05 2017-05-11 Leica Microsystems Cms Gmbh Mikroskop für die Durchlicht- und Fluoreszenzmikroskopie
US10255511B2 (en) * 2016-01-04 2019-04-09 Texas Instruments Incorporated Real time traffic sign recognition
US10324041B2 (en) 2016-12-21 2019-06-18 Abbott Japan Co., Ltd. Optical imaging system using lateral illumination for digital assays
US11047854B2 (en) 2017-02-06 2021-06-29 Abbott Japan Llc Methods for reducing noise in signal-generating digital assays
DE102017107348B4 (de) * 2017-04-05 2019-03-14 Olympus Soft Imaging Solutions Gmbh Verfahren zur zytometrischen Analyse von Zellproben
JP7095075B2 (ja) * 2017-04-28 2022-07-04 マイクロワイズ アンパーツゼルスカブ 生きた有機体を定量化するための方法および装置、ならびに装置の使用
JP2021529951A (ja) * 2018-06-28 2021-11-04 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California 画像データを組み合わせることによる染色組織試料の合成画像の作成
CN112601950B (zh) * 2018-08-22 2023-07-28 仪景通株式会社 图像处理装置、摄像系统、图像处理装置的工作方法以及图像处理装置的工作程序
EP3644044B1 (de) 2018-10-24 2020-12-23 Leica Biosystems Imaging, Inc. Kamerabelichtungssteuerung bei der erfassung von fluoreszenz-in-situ-hybridisierungs-bildern
EP3948221A4 (de) * 2019-03-27 2022-12-21 Becton, Dickinson and Company Systeme zur zellsortierung auf basis von frequenzcodierten bildern und verfahren zur verwendung davon
JP2022551846A (ja) * 2019-10-03 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 蛍光模倣明視野イメージング

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125828A (en) * 1972-08-04 1978-11-14 Med-El Inc. Method and apparatus for automated classification and analysis of cells
US3999047A (en) * 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US5093866A (en) 1990-02-09 1992-03-03 Hamilton Equine Associates Limited Fluorescence and motility characterization system for cells, bacteria, and particles in fluids
US5162990A (en) 1990-06-15 1992-11-10 The United States Of America As Represented By The United States Navy System and method for quantifying macrophage phagocytosis by computer image analysis
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
GB9215710D0 (en) 1992-07-23 1992-09-09 Inst Of Cancer The Research Analysis of cells
US5294799A (en) 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5432054A (en) 1994-01-31 1995-07-11 Applied Imaging Method for separating rare cells from a population of cells
US5662813A (en) * 1994-10-21 1997-09-02 Bioseparations, Inc. Method for separation of nucleated fetal erythrocytes from maternal blood samples
US5863504A (en) 1995-03-16 1999-01-26 Bio-Rad Laboratories, Inc. Fluorescence imaging instrument utilizing fish
US5642433A (en) 1995-07-31 1997-06-24 Neopath, Inc. Method and apparatus for image contrast quality evaluation
US5764792A (en) * 1996-01-19 1998-06-09 Oncor, Inc. Method and apparatus for processing images
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening

Also Published As

Publication number Publication date
ATE308747T1 (de) 2005-11-15
NO995542D0 (no) 1999-11-12
JP2002514304A (ja) 2002-05-14
EP0981732A1 (de) 2000-03-01
IL132747A0 (en) 2001-03-19
EP0981732B1 (de) 2005-11-02
IL132747A (en) 2002-12-01
AU7482898A (en) 1998-12-08
NO995542L (no) 2000-01-14
WO1998052018A1 (en) 1998-11-19
US6169816B1 (en) 2001-01-02
CA2289930A1 (en) 1998-11-19
CA2289930C (en) 2007-08-07
DE69832167T2 (de) 2006-07-20
AU739834B2 (en) 2001-10-18
HK1029170A1 (en) 2001-03-23

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Owner name: GENETIX CORP., SANTA CLARA, CALIF., US