DE69826834D1 - Thermozyklierapparat mit einem automatisch positionierbaren Deckel - Google Patents

Thermozyklierapparat mit einem automatisch positionierbaren Deckel

Info

Publication number
DE69826834D1
DE69826834D1 DE69826834T DE69826834T DE69826834D1 DE 69826834 D1 DE69826834 D1 DE 69826834D1 DE 69826834 T DE69826834 T DE 69826834T DE 69826834 T DE69826834 T DE 69826834T DE 69826834 D1 DE69826834 D1 DE 69826834D1
Authority
DE
Germany
Prior art keywords
cover
thermal block
thermocycler
chambers
stopper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69826834T
Other languages
English (en)
Other versions
DE69826834T2 (de
Inventor
Rolf Schneebeli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE69826834D1 publication Critical patent/DE69826834D1/de
Application granted granted Critical
Publication of DE69826834T2 publication Critical patent/DE69826834T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00376—Conductive heating, e.g. heated plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Closing Of Containers (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
DE69826834T 1998-05-04 1998-05-04 Thermozyklierapparat mit einem automatisch positionierbaren Deckel Expired - Lifetime DE69826834T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98810400A EP0955097B1 (de) 1998-05-04 1998-05-04 Thermozyklierapparat mit einem automatisch positionierbaren Deckel

Publications (2)

Publication Number Publication Date
DE69826834D1 true DE69826834D1 (de) 2004-11-11
DE69826834T2 DE69826834T2 (de) 2005-12-08

Family

ID=8236072

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69826834T Expired - Lifetime DE69826834T2 (de) 1998-05-04 1998-05-04 Thermozyklierapparat mit einem automatisch positionierbaren Deckel

Country Status (8)

Country Link
US (1) US6197572B1 (de)
EP (1) EP0955097B1 (de)
JP (1) JP4390905B2 (de)
AT (1) ATE278471T1 (de)
CA (1) CA2267708C (de)
DE (1) DE69826834T2 (de)
DK (1) DK0955097T3 (de)
ES (1) ES2229465T3 (de)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799521B2 (en) 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
AU4957699A (en) 1998-06-24 2000-01-10 Chen & Chen, Llc Fluid sample testing system
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
CA2255850C (en) * 1998-12-07 2000-10-17 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Rotary thermocycling apparatus
DE19859586C1 (de) * 1998-12-22 2000-07-13 Mwg Biotech Ag Thermocyclervorrichtung
DE50001774D1 (de) 1999-09-29 2003-05-22 Tecan Trading Ag Maennedorf Thermocycler sowie Hebeelement für Mikrotiterplatte
US6272939B1 (en) 1999-10-15 2001-08-14 Applera Corporation System and method for filling a substrate with a liquid sample
US6365367B1 (en) 1999-12-06 2002-04-02 Cellomics, Inc. Environmental chamber for the analysis of live cells
EP1456642A1 (de) * 1999-12-22 2004-09-15 Applera Corporation Deckelmechanismus
US7169355B1 (en) * 2000-02-02 2007-01-30 Applera Corporation Apparatus and method for ejecting sample well trays
US6719949B1 (en) 2000-06-29 2004-04-13 Applera Corporation Apparatus and method for transporting sample well trays
US6939516B2 (en) 2000-09-29 2005-09-06 Becton, Dickinson And Company Multi-well plate cover and assembly adapted for mechanical manipulation
DE10115848A1 (de) * 2001-03-30 2002-10-10 Biometra Biomedizinische Analy Vorrichtung zur thermischen Beeinflussung von in einem Behältnis enthaltenem, vorzugsweise flüssigem Probenmaterial
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
EP1427531B1 (de) 2001-09-11 2016-10-19 Iquum, Inc. Probenbehälter
US20030072685A1 (en) * 2001-10-11 2003-04-17 Goldman Jeffrey A. Heat conducting sample block
US6942836B2 (en) 2001-10-16 2005-09-13 Applera Corporation System for filling substrate chambers with liquid
DE20117661U1 (de) * 2001-10-29 2003-03-13 Mwg Biotech Ag Thermocyclervorrichtung
US6677151B2 (en) 2002-01-30 2004-01-13 Applera Corporation Device and method for thermal cycling
US7452712B2 (en) * 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US6730883B2 (en) * 2002-10-02 2004-05-04 Stratagene Flexible heating cover assembly for thermal cycling of samples of biological material
AU2004220626B2 (en) 2003-02-05 2010-07-29 Iquum Inc. Sample processing tubule
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
US20040258563A1 (en) 2003-06-23 2004-12-23 Applera Corporation Caps for sample wells and microcards for biological materials
US20050225751A1 (en) * 2003-09-19 2005-10-13 Donald Sandell Two-piece high density plate
US20050226779A1 (en) 2003-09-19 2005-10-13 Oldham Mark F Vacuum assist for a microplate
US20050221358A1 (en) * 2003-09-19 2005-10-06 Carrillo Albert L Pressure chamber clamp mechanism
US7570443B2 (en) * 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US7460223B2 (en) * 2003-09-19 2008-12-02 Applied Biosystems Inc. Inverted orientation for a microplate
US20050237528A1 (en) * 2003-09-19 2005-10-27 Oldham Mark F Transparent heater for thermocycling
US7788039B2 (en) 2003-09-25 2010-08-31 Roche Molecular Systems, Inc. Quantitation of nucleic acids using growth curves
US20080118955A1 (en) * 2004-04-28 2008-05-22 International Business Machines Corporation Method for precise temperature cycling in chemical / biochemical processes
US20050244933A1 (en) * 2004-04-28 2005-11-03 International Business Machines Corporation Method and apparatus for precise temperature cycling in chemical/biochemical processes
US20060030037A1 (en) * 2004-05-28 2006-02-09 Victor Joseph Thermo-controllable high-density chips for multiplex analyses
US20050282270A1 (en) * 2004-06-21 2005-12-22 Applera Corporation System for thermally cycling biological samples with heated lid and pneumatic actuator
EP1869158B1 (de) * 2005-03-22 2013-05-29 Life Technologies Corporation Druckkammer-klemmverfahren
JP4682008B2 (ja) * 2005-10-04 2011-05-11 キヤノン株式会社 生化学処理装置、これに用いる容器および検査装置
WO2008002563A2 (en) * 2006-06-26 2008-01-03 Applera Corporation Heated cover methods and technology
JP2010516281A (ja) 2007-01-22 2010-05-20 ウェハージェン，インコーポレイテッド 高スループット化学反応用装置
EP1964609B1 (de) * 2007-02-13 2018-07-18 Eppendorf Ag Verfahren zum Abdecken von Proben mit probengrößenunabhängiger Höhenregulierung
US20080318280A1 (en) * 2007-02-13 2008-12-25 Eppendorf Ag Cover for an array of reaction vessels for one-step operation modus
EP1961484B1 (de) 2007-02-13 2016-07-20 Eppendorf Ag Deckel für Proben mit homogener Druckanwendung
WO2009046227A1 (en) 2007-10-02 2009-04-09 Theranos, Inc. Modular point-of-care devices and uses thereof
US8460621B2 (en) * 2007-10-15 2013-06-11 Biocision, Llc Temperature transfer stand
JP5395098B2 (ja) * 2008-02-15 2014-01-22 バイオ−ラッド ラボラトリーズ，インコーポレイティド 自動調整する蓋を有するサーマルサイクラー
US20110156090A1 (en) * 2008-03-25 2011-06-30 Lin Charles W C Semiconductor chip assembly with post/base/post heat spreader and asymmetric posts
DE202008009556U1 (de) * 2008-07-16 2009-12-03 Eppendorf Ag Vorrichtung zum Temperieren wenigstens einer Probe
GB0909420D0 (en) * 2009-06-02 2009-07-15 Biochip Devises Pte Ltd Device for nucleic acid amplification
GB2512764B (en) * 2009-08-08 2014-12-24 Bibby Scient Ltd An apparatus for treating a test sample
GB2511692A (en) * 2009-08-08 2014-09-10 Bibby Scient Ltd An apparatus for treating a test sample
EP2749887A3 (de) * 2010-07-23 2014-10-01 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
EP2615462B1 (de) * 2010-11-15 2016-12-14 F. Hoffmann-La Roche AG Instrument und Verfahren zur automatisierten Wärmebehandlung von Flüssigkeitsproben
US9446410B2 (en) 2010-12-03 2016-09-20 Biofire Defense, Llc Thermal cycler apparatus with elastomeric adhesive
CA3097861A1 (en) 2011-01-21 2012-07-26 Labrador Diagnostics Llc Systems and methods for sample use maximization
DE102011011912B4 (de) 2011-02-21 2020-09-03 Eppendorf Ag Laborgerät mit Deckel und Pressanordnung und Verfahren zum Anpressen
TW201239088A (en) * 2011-03-22 2012-10-01 Genereach Biotechnology Corp Convective polymerase chain reaction device
EP2525211B1 (de) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument und verfahren zum detektieren von analyten
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US20140308661A1 (en) * 2011-09-25 2014-10-16 Theranos, Inc. Systems and methods for multi-analysis
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
AU2013202793B2 (en) 2012-07-31 2014-09-18 Gen-Probe Incorporated System, method and apparatus for automated incubation
AU2014277774C1 (en) * 2012-07-31 2019-09-19 Gen-Probe Incorporated System, Method and Apparatus for Automated Incubation
DE102013200193A1 (de) * 2013-01-09 2014-07-10 Hamilton Bonaduz Ag Probenverarbeitungssystem mit Dosiervorrichtung und Thermocycler
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
US20140273181A1 (en) 2013-03-15 2014-09-18 Biofire Diagnostics, Inc. Compact optical system for substantially simultaneous monitoring of samples in a sample array
KR102091303B1 (ko) 2013-03-19 2020-03-19 라이프 테크놀로지스 코포레이션 열 순환기 커버
CN105324698B (zh) 2013-05-01 2019-07-02 生物辐射实验室股份有限公司 可调节的数字显微镜显示
WO2014179483A2 (en) * 2013-05-02 2014-11-06 Bio-Rad Laboratories, Inc. Drawer handle mechanism
US10422806B1 (en) 2013-07-25 2019-09-24 Theranos Ip Company, Llc Methods for improving assays of biological samples
GB201319759D0 (en) * 2013-11-08 2013-12-25 Thomsen Lars Device and method for heating a fluid chamber
GB2591198B (en) * 2014-04-04 2021-10-27 It Is Int Ltd Biochemical reaction system
CN106459871A (zh) * 2014-05-21 2017-02-22 卡尤迪生物科技（北京）有限公司 热循环仪盖子配置及其用途
EP3169601A4 (de) 2014-07-16 2018-01-17 Synthetic Genomics, Inc. Deckelmechanismus
EP3253492B1 (de) * 2015-02-06 2024-04-03 Life Technologies Corporation Systeme zur biologischen analyse
CN107407685B (zh) 2015-02-20 2021-08-03 宝生物工程（美国)有限公司 快速精确分配、可视化和分析单个细胞的方法
CN106680250B (zh) * 2015-11-10 2023-06-30 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
SG11201805140VA (en) * 2015-12-22 2018-07-30 Life Technologies Corp Systems and methods for a thermal cycler heated cover
JP7075394B2 (ja) 2016-07-21 2022-05-25 タカラ バイオ ユーエスエー， インコーポレイテッド マルチウェルデバイスを用いたマルチｚ撮像及び分注
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
CN111372650A (zh) * 2017-09-30 2020-07-03 因思科瑞普特公司 流通式电穿孔仪器
US11708551B2 (en) * 2017-10-06 2023-07-25 Wyatt Technology Corporation Temperature uniformity and suppressing well plate warping in high throughput measurements
WO2019200004A1 (en) * 2018-04-13 2019-10-17 Inscripta, Inc. Automated cell processing instruments comprising reagent cartridges
DE102018124408A1 (de) * 2018-10-02 2020-04-02 Biometra GmbH Vorrichtung zur thermischen Behandlung von Proben
DE102018124412A1 (de) * 2018-10-02 2020-04-02 Biometra GmbH Temperierblockmodul und Vorrichtung zur thermischen Behandlung von Proben
DE102018131127A1 (de) 2018-12-06 2020-06-10 Analytik Jena Ag Automatisierbare Temperiervorrichtung
CN113811596A (zh) * 2019-01-30 2021-12-17 生命技术控股私人有限公司 生物分析系统和方法
CN112881719B (zh) * 2019-11-30 2024-01-16 深圳市帝迈生物技术有限公司 血液分析仪、检测装置
EP4146398A1 (de) * 2020-05-08 2023-03-15 Life Technologies Holdings Pte Limited Biologische analysesysteme und -verfahren
EP4188605A1 (de) * 2020-07-31 2023-06-07 Seegene, Inc. Thermocycler mit dämpfungsmodul
JPWO2022091583A1 (de) * 2020-10-26 2022-05-05
TW202338077A (zh) * 2022-03-22 2023-10-01 列特博生技股份有限公司 多功能聚合酶連鎖反應裝置及其操作方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311440B1 (de) * 1987-10-09 1992-06-24 Seiko Instruments Inc. Gerät zum Durchführen einer Flüssigkeitsreaktion
US5556958A (en) * 1989-10-26 1996-09-17 Steritech, Inc. Inactivation of pathogens in clinical samples
CA2031912A1 (en) * 1989-12-22 1991-06-23 Robert Fred Pfost Heated cover device
KR100236506B1 (ko) * 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 폴리머라제 연쇄 반응 수행 장치
US5282543A (en) * 1990-11-29 1994-02-01 The Perkin Elmer Corporation Cover for array of reaction tubes
EP0542422A1 (de) * 1991-11-12 1993-05-19 General Atomics Mikrotiterplatte mit mehreren Vertiefungen
WO1994012885A1 (en) * 1992-11-20 1994-06-09 Dainabot Co., Ltd. Multi-channel automatic immunoassay system
CA2130013C (en) * 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
JP3051626B2 (ja) * 1993-12-09 2000-06-12 富士写真フイルム株式会社 インキュベータ

Also Published As

Publication number Publication date
JP2000050867A (ja) 2000-02-22
ES2229465T3 (es) 2005-04-16
EP0955097B1 (de) 2004-10-06
DE69826834T2 (de) 2005-12-08
US6197572B1 (en) 2001-03-06
EP0955097A1 (de) 1999-11-10
CA2267708C (en) 2008-08-05
DK0955097T3 (da) 2005-02-14
CA2267708A1 (en) 1999-11-04
ATE278471T1 (de) 2004-10-15
JP4390905B2 (ja) 2009-12-24

Similar Documents

Publication Publication Date Title
DE69826834D1 (de) Thermozyklierapparat mit einem automatisch positionierbaren Deckel
DE59410020D1 (de) Vorrichtung zur automatischen Durchführung von Polymerase-Kettenreaktionen
DE69233471D1 (de) Informationsverarbeitungsapparat
ATE398022T1 (de) Abdeckmechanismus undtintenstrahlaufzeichnungsgerät das diesen abdeckmechanismus verwendet
BE894384A (fr) Revetements durcissables par infiltration de vapeur pour pieces moulees par injection avec reaction
FI930393A0 (fi) Telakone
DE69102878T2 (de) Gaskühler zur wärmeübertragung durch strahlung.
GR3005695T3 (de)
DK0845414T3 (da) Indretning til at overføre i det væsentlige runde, skrøbelige genstande såsom æg
KR930003289A (ko) 종형 열 처리장치
SE9302492L (sv) Anordning vid sidovarmgöt med bottenplatta
BR9107252A (pt) Dispositivo de insercao e de troca de tubo de vazamento
DE59100136D1 (de) Vorrichtung zum erwaermen von fluessigkeiten, insbesondere zum erwaermen von infusions- und/oder transfusionsfluessigkeiten.
DE69513627T2 (de) Vorrichtung zum Einsetzen einer Abdeckplatte in einer Zufuhr- und Austauschvorrichtung eines Tauchrohres
ES2023981B3 (es) Dispositivo de cierre
EP1136262A3 (de) Vorrichtung für den Antrieb eines Vorgreifers
ATE7403T1 (de) Naehrbodentraegersystem.
DE69102879D1 (de) Gaskühler zur wärmeübertragung durch konvektion.
KR900002440A (ko) 피가공물 가열이송장치
ES2153932T3 (es) Deposito y metodo para el tratamiento termico de envases de alimentos.
ATE86169T1 (de) Vorrichtung zum erwaermen einer keimfreien kunststoffbahn.
JPS6472875A (en) Serial-type printer
JPS5353222A (en) Print controlling system
FR2720101B1 (fr) Dispositif pour coulisser un portail bois ou PVC de forme supérieure autre que droite.
DE69203411D1 (de) Vorrichtung zum Transfer von Scheiben, insbesondere Silicon-Scheiben.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: DURM & PARTNER, 76133 KARLSRUHE