DE69736300D1 - Detektionsvorrichtung zur Messung des Sauerstoffgehaltes im Gewebe - Google Patents

Detektionsvorrichtung zur Messung des Sauerstoffgehaltes im Gewebe

Info

Publication number
DE69736300D1
DE69736300D1 DE69736300T DE69736300T DE69736300D1 DE 69736300 D1 DE69736300 D1 DE 69736300D1 DE 69736300 T DE69736300 T DE 69736300T DE 69736300 T DE69736300 T DE 69736300T DE 69736300 D1 DE69736300 D1 DE 69736300D1
Authority
DE
Germany
Prior art keywords
tissue
measuring
detection device
oxygen content
fluorphor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69736300T
Other languages
English (en)
Other versions
DE69736300T2 (de
Inventor
F Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxygen Enterprises Ltd
Original Assignee
Oxygen Enterprises Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxygen Enterprises Ltd filed Critical Oxygen Enterprises Ltd
Publication of DE69736300D1 publication Critical patent/DE69736300D1/de
Application granted granted Critical
Publication of DE69736300T2 publication Critical patent/DE69736300T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
DE69736300T 1996-12-16 1997-12-12 Detektionsvorrichtung zur Messung des Sauerstoffgehaltes im Gewebe Expired - Fee Related DE69736300T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US767305 1991-09-27
US08/767,305 US5830138A (en) 1996-12-16 1996-12-16 Intravascular catheter probe for clinical oxygen, pH and CO2 measurement
PCT/US1997/023605 WO1998026709A1 (en) 1996-12-16 1997-12-12 INTRAVASCULAR CATHETER PROBE FOR CLINICAL OXYGEN, pH AND CO2 MEASUREMENT

Publications (2)

Publication Number Publication Date
DE69736300D1 true DE69736300D1 (de) 2006-08-17
DE69736300T2 DE69736300T2 (de) 2007-07-05

Family

ID=25079084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69736300T Expired - Fee Related DE69736300T2 (de) 1996-12-16 1997-12-12 Detektionsvorrichtung zur Messung des Sauerstoffgehaltes im Gewebe

Country Status (8)

Country Link
US (1) US5830138A (de)
EP (1) EP0971623B1 (de)
JP (1) JP2001509888A (de)
AT (1) ATE332101T1 (de)
AU (1) AU719524B2 (de)
CA (1) CA2275231C (de)
DE (1) DE69736300T2 (de)
WO (1) WO1998026709A1 (de)

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CA2387492C (en) * 1999-10-14 2012-07-10 The Trustees Of The University Of Pennsylvania Apparatus for measuring an oxygen concentration gradient and method of use thereof
US6395555B1 (en) * 1999-10-14 2002-05-28 David F. Wilson Method and apparatus for determining the effect of a drug on cells
US6701168B1 (en) 1999-10-14 2004-03-02 Trustees Of The University Of Pennsylvania Apparatus for measuring an oxygen concentration gradient and method of use thereof
US20010034479A1 (en) * 2000-04-19 2001-10-25 Ring Lawrence S. Optically based transcutaneous blood gas sensor
US6839375B1 (en) * 2001-09-06 2005-01-04 Lambda Physik Ag On-line quality control of the key optical components in lithography lasers using laser induced fluorescence
US6970492B2 (en) * 2002-05-17 2005-11-29 Lambda Physik Ag DUV and VUV laser with on-line pulse energy monitor
EP1526801A2 (de) * 2002-08-05 2005-05-04 Miravant Medical Technologies Inc. Katheter für diagnose und zur behandlung von erkrankten blutgefässe
US20040107986A1 (en) * 2002-12-06 2004-06-10 Neilson Andy C. High throughput microcalorimeter systems and methods
WO2004065618A2 (en) * 2003-01-16 2004-08-05 Thermogenic Imaging Methods and devices for monitoring cellular metabolism in microfluidic cell-retaining chambers
US6999807B2 (en) * 2003-01-23 2006-02-14 Scimed Life Systems, Inc. pH measuring balloon
US7276351B2 (en) 2003-09-10 2007-10-02 Seahorse Bioscience Method and device for measuring multiple physiological properties of cells
US20070087401A1 (en) * 2003-10-17 2007-04-19 Andy Neilson Analysis of metabolic activity in cells using extracellular flux rate measurements
US8658349B2 (en) 2006-07-13 2014-02-25 Seahorse Bioscience Cell analysis apparatus and method
DE102004033303A1 (de) * 2004-04-16 2005-11-03 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Vorrichtung zur Bestimmung und/oder Überwachung eines in einem fluiden Prozessmedium enthaltenen Analyten
SE0401632D0 (sv) * 2004-06-24 2004-06-24 Innovation Team Ab Medel och sätt att detektera blodläckage från sår
US9044179B2 (en) * 2006-01-04 2015-06-02 The Trustees Of The University Of Pennslyvania Oxygen sensor for internal monitoring of tissue oxygen in vivo
US8126554B2 (en) 2006-05-17 2012-02-28 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
US8801652B2 (en) 2006-07-27 2014-08-12 Fresenius Medical Care Holding, Inc. Early stage peritonitis detection apparatus and methods
US8728023B2 (en) 2006-07-27 2014-05-20 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection including self-cleaning effluent chamber
US8777891B2 (en) 2006-07-27 2014-07-15 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection and for in vivo testing of bodily fluid
WO2008118042A1 (en) * 2007-03-23 2008-10-02 St. Jude Medical Ab Implantable medical device
JP5596558B2 (ja) * 2008-01-25 2014-09-24 フレセニウス メディカル ケア ホールディングス インコーポレーテッド 早期の腹膜炎検出及び体液の生体内検査のための装置
US8202702B2 (en) * 2008-10-14 2012-06-19 Seahorse Bioscience Method and device for measuring extracellular acidification and oxygen consumption rate with higher precision
US8694069B1 (en) 2009-12-21 2014-04-08 Kosense, LLC Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring
US20120129268A1 (en) * 2010-11-19 2012-05-24 Mayer Daniel W Photoluminescent oxygen probe with reduced cross-sensitivity to humidity
WO2013011955A1 (ja) 2011-07-15 2013-01-24 国立大学法人九州大学 遅延蛍光材料およびそれを用いた有機エレクトロルミネッセンス素子
KR102006506B1 (ko) 2011-07-15 2019-08-01 가부시키가이샤 큐럭스 유기 일렉트로 루미네선스 소자 및 그것에 사용하는 화합물
JP5590573B2 (ja) * 2011-07-15 2014-09-17 国立大学法人九州大学 酸素センサー
US9494577B2 (en) 2012-11-13 2016-11-15 Seahorse Biosciences Apparatus and methods for three-dimensional tissue measurements based on controlled media flow
US9175944B2 (en) * 2012-12-10 2015-11-03 The Johns Hopkins University Durable single mode fiber probe with optimized reference reflectivity
EP3148700B1 (de) 2014-06-02 2020-03-18 Agilent Technologies, Inc. Einspaltiges mikroplattensystem und träger zur analyse biologischer proben
RU2579149C1 (ru) * 2015-04-03 2016-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ивановский государственный химико-технологический университет" (ИГХТУ) Способ получения комплексов лютеция и гадолиния с тетрабензопорфирином
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
RU2622292C1 (ru) * 2016-06-21 2017-06-14 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ивановский государственный химико-технологический университет" (ИГХТУ) Способ получения комплексов лантаноидов с 5, 15-дифенилтетрабензопорфином
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
CN109864746B (zh) 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
CN111117600A (zh) * 2019-12-27 2020-05-08 复旦大学 一种氧气纳米探针及其制备方法与应用
DE102020123031A1 (de) * 2020-09-03 2022-03-03 Karl Storz Se & Co. Kg Beleuchtungsvorrichtung mit Lichtleitererkennung

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US3814081A (en) * 1971-04-02 1974-06-04 Olympus Optical Co Optical measuring catheter
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US4200110A (en) * 1977-11-28 1980-04-29 United States Of America Fiber optic pH probe
US4476870A (en) * 1982-03-30 1984-10-16 The United States Of America As Represented By The Department Of Health And Human Services Fiber optic PO.sbsb.2 probe
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US5012809A (en) * 1986-10-10 1991-05-07 Shulze John E Fiber optic catheter system with fluorometric sensor and integral flexure compensation
US4785814A (en) * 1987-08-11 1988-11-22 Cordis Corporation Optical probe for measuring pH and oxygen in blood and employing a composite membrane
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US5127405A (en) * 1990-02-16 1992-07-07 The Boc Group, Inc. Biomedical fiber optic probe with frequency domain signal processing
US6362175B1 (en) * 1991-09-20 2002-03-26 The Trustees Of The University Of Pennsylvania Porphyrin compounds for imaging tissue oxygen
GB9127390D0 (en) * 1991-12-24 1992-02-19 Medicina Ltd Gastric probe
AT397458B (de) * 1992-09-25 1994-04-25 Avl Verbrennungskraft Messtech Sensoranordnung
WO1994010553A1 (en) * 1992-10-23 1994-05-11 Optex Biomedical, Inc. Fibre-optic probe for the measurement of fluid parameters
US5515864A (en) * 1994-04-21 1996-05-14 Zuckerman; Ralph Method and apparatus for the in vivo measurement of oxygen concentration levels by the indirect determination of fluoescence lifetime

Also Published As

Publication number Publication date
ATE332101T1 (de) 2006-07-15
EP0971623A4 (de) 2001-08-29
AU5614698A (en) 1998-07-15
EP0971623A1 (de) 2000-01-19
WO1998026709A1 (en) 1998-06-25
DE69736300T2 (de) 2007-07-05
US5830138A (en) 1998-11-03
AU719524B2 (en) 2000-05-11
CA2275231C (en) 2010-11-09
JP2001509888A (ja) 2001-07-24
CA2275231A1 (en) 1998-06-25
EP0971623B1 (de) 2006-07-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee