DE69733605D1 - In vivo gentransfermethoden zur wundheilung - Google Patents
In vivo gentransfermethoden zur wundheilungInfo
- Publication number
- DE69733605D1 DE69733605D1 DE69733605T DE69733605T DE69733605D1 DE 69733605 D1 DE69733605 D1 DE 69733605D1 DE 69733605 T DE69733605 T DE 69733605T DE 69733605 T DE69733605 T DE 69733605T DE 69733605 D1 DE69733605 D1 DE 69733605D1
- Authority
- DE
- Germany
- Prior art keywords
- dna
- interest
- vivo
- gentransfer
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6953—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a fibre, a textile, a slab or a sheet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/631,334 US5962427A (en) | 1994-02-18 | 1996-04-12 | In vivo gene transfer methods for wound healing |
US631334 | 1996-04-12 | ||
PCT/US1997/007301 WO1997038729A1 (en) | 1996-04-12 | 1997-04-11 | In vivo gene transfer methods for wound healing |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69733605D1 true DE69733605D1 (de) | 2005-07-28 |
DE69733605T2 DE69733605T2 (de) | 2006-05-11 |
Family
ID=24530760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69733605T Expired - Lifetime DE69733605T2 (de) | 1996-04-12 | 1997-04-11 | In vivo gentransfermethoden zur wundheilung |
Country Status (12)
Country | Link |
---|---|
US (1) | US5962427A (de) |
EP (2) | EP1510224A1 (de) |
JP (1) | JP4114952B2 (de) |
CN (2) | CN102274522A (de) |
AT (1) | ATE298253T1 (de) |
AU (1) | AU710386B2 (de) |
CA (1) | CA2251655C (de) |
DE (1) | DE69733605T2 (de) |
NO (1) | NO323843B1 (de) |
PL (1) | PL189174B1 (de) |
RU (1) | RU2170104C2 (de) |
WO (1) | WO1997038729A1 (de) |
Families Citing this family (119)
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US6551618B2 (en) * | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
US6528483B2 (en) | 1995-06-07 | 2003-03-04 | André Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
DK1486565T3 (da) * | 1995-10-11 | 2008-03-10 | Novartis Vaccines & Diagnostic | Kombination af PDGF, KGF, IGF og IGFBP til sårheling |
US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
US6387700B1 (en) | 1996-11-04 | 2002-05-14 | The Reagents Of The University Of Michigan | Cationic peptides, Cys-Trp-(LYS)n, for gene delivery |
AU6691098A (en) * | 1997-03-07 | 1998-09-22 | Wistar Institute Of Anatomy & Biology, The | Method and compositions for healing tissue defects and inducing hypervascularityin mammalian tissue |
US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US20050186283A1 (en) | 1997-10-10 | 2005-08-25 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material, and method |
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US6475994B2 (en) * | 1998-01-07 | 2002-11-05 | Donald A. Tomalia | Method and articles for transfection of genetic material |
US6395253B2 (en) | 1998-04-23 | 2002-05-28 | The Regents Of The University Of Michigan | Microspheres containing condensed polyanionic bioactive agents and methods for their production |
US20030039694A1 (en) * | 1998-04-28 | 2003-02-27 | Martin John Francis | Periadventitial delivery device |
WO1999058656A2 (en) * | 1998-05-13 | 1999-11-18 | The Regents Of The University Of Michigan | Sustained dna delivery from structural matrices |
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US6767928B1 (en) | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
AU4173000A (en) * | 1999-03-19 | 2000-10-09 | Regents Of The University Of Michigan, The | Mineralization and cellular patterning on biomaterial surfaces |
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US6770740B1 (en) | 1999-07-13 | 2004-08-03 | The Regents Of The University Of Michigan | Crosslinked DNA condensate compositions and gene delivery methods |
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CA2236807A1 (en) * | 1995-11-06 | 1997-05-15 | Rita Kandel | Reconstituted mineralized cartilage tissue |
-
1996
- 1996-04-12 US US08/631,334 patent/US5962427A/en not_active Expired - Lifetime
-
1997
- 1997-04-11 DE DE69733605T patent/DE69733605T2/de not_active Expired - Lifetime
- 1997-04-11 AT AT97922578T patent/ATE298253T1/de active
- 1997-04-11 EP EP04027225A patent/EP1510224A1/de not_active Ceased
- 1997-04-11 CA CA2251655A patent/CA2251655C/en not_active Expired - Fee Related
- 1997-04-11 AU AU28212/97A patent/AU710386B2/en not_active Ceased
- 1997-04-11 WO PCT/US1997/007301 patent/WO1997038729A1/en active IP Right Grant
- 1997-04-11 PL PL97343864A patent/PL189174B1/pl not_active IP Right Cessation
- 1997-04-11 JP JP53746397A patent/JP4114952B2/ja not_active Expired - Fee Related
- 1997-04-11 CN CN2011102033716A patent/CN102274522A/zh active Pending
- 1997-04-11 CN CN97195326A patent/CN1226835A/zh active Pending
- 1997-04-11 EP EP97922578A patent/EP0892644B1/de not_active Expired - Lifetime
- 1997-04-11 RU RU98120477/14A patent/RU2170104C2/ru not_active IP Right Cessation
-
1998
- 1998-10-09 NO NO19984729A patent/NO323843B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69733605T2 (de) | 2006-05-11 |
EP0892644A1 (de) | 1999-01-27 |
NO984729L (no) | 1998-12-14 |
NO323843B1 (no) | 2007-07-09 |
JP2001519767A (ja) | 2001-10-23 |
EP0892644B1 (de) | 2005-06-22 |
CN102274522A (zh) | 2011-12-14 |
ATE298253T1 (de) | 2005-07-15 |
WO1997038729A8 (en) | 1999-04-22 |
JP4114952B2 (ja) | 2008-07-09 |
RU2170104C2 (ru) | 2001-07-10 |
CN1226835A (zh) | 1999-08-25 |
PL189174B1 (pl) | 2005-06-30 |
WO1997038729A1 (en) | 1997-10-23 |
AU710386B2 (en) | 1999-09-16 |
EP1510224A1 (de) | 2005-03-02 |
AU2821297A (en) | 1997-11-07 |
US5962427A (en) | 1999-10-05 |
CA2251655A1 (en) | 1997-10-23 |
PL343864A1 (en) | 2001-09-10 |
CA2251655C (en) | 2010-09-21 |
EP0892644A4 (de) | 1999-07-14 |
NO984729D0 (no) | 1998-10-09 |
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